heptacaine has been researched along with piperidines in 62 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (58.06) | 18.7374 |
1990's | 13 (20.97) | 18.2507 |
2000's | 10 (16.13) | 29.6817 |
2010's | 3 (4.84) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Blesová, M; Borovanský, A; Cizmárik, J; Subert, J | 1 |
Borovanský, A; Cizmárik, J; Svec, P | 1 |
Borovanský, A; Cizmárik, J; Mazáñ, S; Svec, P | 1 |
Borovanský, A; Cizmárik, J; Kozlovský, J; Pesak, M | 1 |
Bachratá, M; Bezáková, Z; Blesová, M; Stankovicová, M | 1 |
Cizmárik, J; Medvecký, R; Minh, DN; Racanská, E | 1 |
Siekel, P | 1 |
Bezek, S; Durisová, M; Kállay, Z; Kukan, M; Laginová, V; Scasnár, V; Svoboda, V; Trnovec, T | 1 |
Drábiková, K; Jancinová, V; Nosál', R | 1 |
Cizmárik, J; Duncková, E; Springer, V | 1 |
Béderová, E; Pisková, L; Racanský, V | 1 |
Horváth, LI; Mazúr, M; Stolc, S | 1 |
Bachratá, A; Bezáková, Z; Blesová, M; Cizmárik, J | 1 |
Cizmárik, J; Ebringer, L; Lahitová, N | 2 |
Cizmárik, J; Trupl, J | 1 |
Bauer, V; Bezeková, M; Matusák, O | 1 |
Cizmárik, J; Duncková, E; Lehotay, J; Springer, V | 1 |
Bezek, S; Durisovă, M; Kállay, Z; Scasnár, V; Trnovec, T | 1 |
Bauer, V; Benes, L; Bezeková, M; Cílková, D | 1 |
Ebringer, L; Foltínová, P; Lahitová, N | 1 |
Kapeller, K; Murín, A; Nyitrayová, O | 1 |
Bózner, A; Cizmárik, J; Hricková-Pazin, E; Zelenay, R | 1 |
Hynie, S; Klenerová, V; Wenke, M | 1 |
Balgavý, P; Benes, L; Ondrias, K; Stolc, S | 1 |
Balgavý, P; Horváth, LI; Ondrias, K; Stolc, S | 1 |
Brechtlová, M; Cizmárik, J; Krizko, J; Líska, B; Uhlíková, E | 1 |
Bózner, A; Bukovský, M; Cizmárik, J; Zelenay, R | 1 |
Catár, G; Cizmárik, J; Karasová, M; Kieferová, L | 1 |
Cizmárik, J; Karasová, M; Kieferová, L; Lahitová, N | 1 |
Cizmárik, J; Pesák, M; Trupl, J | 1 |
Balgavý, P; Cizmárik, J; Gawrisch, K; Národa, J | 1 |
Cizmárik, J; Helia, O | 1 |
Dráberová, L; Nouza, K | 1 |
Borovanský, A; Cizmárik, J; Inczinger, F; Kozlovský, J; Pesák, M | 1 |
kucárová, M; Pesak, M; Stankovicová, M; Vavro, P | 1 |
Cizmárik, J; Faith, L; Svec, P | 1 |
Cizmárik, J; Svec, J; Svec, P | 1 |
Babul'ová, A; Bauer, V; Benes, L; Buran, L; Petkov, V; Todorov, S; Zamfirova, R | 1 |
Cizmárik, J; Michalov, J; Szücsová, S | 1 |
Brandsteterová, E; Cizmárik, J; Lehotay, J | 1 |
Balgavý, P; Cizmárik, J; Gallová, J | 1 |
Cizmárik, J; Gardavská, K; Vitková, Z | 2 |
Balgavý, P; Hammel, M; Uhríková, D | 2 |
Cizmárik, J; Gardavská, K; Rak, J; Vitková, Z | 1 |
Andriamainty, F; Balgavý, P; Gallová, J; Uhríkova, D | 1 |
Bánó, M; Pajdalová, O | 1 |
Andriamainty, F; Cizmárik, J | 3 |
Svehlová, E | 1 |
Bánó, M | 1 |
Bednáriková, A; Cizmárik, J; Lehotay, J | 1 |
Bukovsky, M; Vegh, V | 1 |
Cizmarik, J; Hahnenkamp, K; Vegh, V | 1 |
Andriamainty, F; Cizmárik, J; Malík, I; Sedlárová, E; Zúdorová, Z | 1 |
Andriamainty, F; Cizmárik, J; Horvat, S; Malík, I | 1 |
Cizmárik, J; Herdová, P; Vitková, Z | 1 |
Bezáková, Z; Cižmárik, J; Lašáková, A; Medlenová, V; Stankovičová, M | 1 |
Andriamainty, F; Čižmárik, J; Gališinová, J; Gálusová, A; Salanci, E; Stopková, L | 1 |
1 review(s) available for heptacaine and piperidines
Article | Year |
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Is there a place for local anesthetics structurally different from classical amid or ester local anesthetics?
Topics: Amides; Anesthetics, Local; Animals; Carbamates; Dose-Response Relationship, Drug; Esters; Humans; Hydrogen-Ion Concentration; Lethal Dose 50; Molecular Structure; Phenylcarbamates; Piperidines; Sciatic Nerve; Structure-Activity Relationship | 2006 |
61 other study(ies) available for heptacaine and piperidines
Article | Year |
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[Choice of the reaction component for the extraction photometric determination of heptacaine].
Topics: Anesthetics, Local; Azo Compounds; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Methods; Photometry; Piperidines | 1978 |
N-[2-(2-Heptyloxyphenylcarbomoyloxy)-ethyl]-piperidinium chloride, heptacaine, a new local anaesthetic.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Blood Pressure; Heart Rate; Lethal Dose 50; Mice; Motor Activity; Muscle Contraction; Mutagens; Piperidines; Rats; Sleep | 1978 |
Quaternary ammonium salts of heptacaine.
Topics: Anesthetics, Local; Chemical Phenomena; Chemistry; Piperidines; Quaternary Ammonium Compounds | 1978 |
[Studies on local anesthetics. LVIII. Comparison of the anti-arrhythmia effect of heptacaine and lidocaine].
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Guinea Pigs; Humans; Lidocaine; Male; Ouabain; Piperidines | 1976 |
Study of the relation between physico-chemical properties and the biological activity of basic heptacaine analogues.
Topics: Chemical Phenomena; Chemistry, Physical; Piperidines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1992 |
Study of local anaesthetics. Part 98(3): Preparation and local anaesthetic activity of 4-alkylpiperazinoethyl esters of o-heptyloxyphenylcarbamic acid.
Topics: Anesthetics, Local; Animals; Carbamates; Cocaine; Guinea Pigs; Lethal Dose 50; Mice; Piperazines; Piperidines; Procaine | 1992 |
A genotoxicological study of the new local anaesthetic carbamate derivatives carbisocaine, heptacaine and pentacaine.
Topics: Anesthetics, Local; Animals; Carbamates; DNA Repair; Drosophila melanogaster; Escherichia coli; Euglena; Genes, Lethal; Genes, Recessive; Mutagenicity Tests; Mutagens; Piperidines; Salmonella typhimurium | 1990 |
Irradiation of the head by 60Co opens the blood-brain barrier for drugs in rats.
Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Carbamates; Chloramphenicol; Cobalt Radioisotopes; Cranial Irradiation; Diazepam; Etimizol; Male; Piperidines; Rats; Rats, Inbred Strains; Regression Analysis | 1990 |
[Interaction of local anesthetics with secretory cells at the membrane level].
Topics: Anesthetics, Local; Animals; Blood Platelets; Carbamates; Histamine Release; In Vitro Techniques; Male; Mast Cells; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
[Determination of heptacaine hydrochloride and its metabolites in human urine and blood].
Topics: Anesthetics, Local; Humans; Piperidines; Spectrophotometry, Ultraviolet | 1989 |
The influence of local anesthetics on the gel-liquid crystal phase transition in model dipalmitoylphosphatidylcholine membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Cocaine; Dibucaine; Electron Spin Resonance Spectroscopy; Gels; Lidocaine; Lipid Bilayers; Microscopy, Polarization; Physical Phenomena; Physics; Piperidines; Tetracaine | 1988 |
A pH-dependent disordering efficacy of new local anaesthetics with carbanilate structure. A spin label study in model membranes.
Topics: Anesthetics, Local; Carbamates; Chemical Phenomena; Chemistry, Physical; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Membranes, Artificial; Models, Chemical; Piperidines; Spin Labels | 1986 |
Pentacaine hydrochloride, carbisocaine hydrochloride and heptacaine hydrochloride--long-time and short-time tests in study of stability.
Topics: Carbamates; Chemical Phenomena; Chemistry; Drug Stability; Hydrogen-Ion Concentration; Piperidines; Temperature; Time Factors; Ultraviolet Rays | 1987 |
[Mutagenicity tests of the local anesthetic, heptacaine, and its alkoxy analogs].
Topics: Anesthetics, Local; Animals; Carbamates; Escherichia coli; Female; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Piperidines; Salmonella typhimurium | 1986 |
[Antimicrobial action of quaternary ammonium salts of heptacaine].
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry; Microbial Sensitivity Tests; Piperidines | 1987 |
The effect of local anaesthetics on noncholinergic-nonadrenergic (NCNA) responses of the gut.
Topics: Action Potentials; Anesthetics, Local; Animals; Carbamates; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Intestines; Male; Piperidines; Procaine; Pyrrolidines; Sympathetic Nervous System; Trimecaine | 1987 |
[Separation of heptacain hydrochloride metabolites with HPLC].
Topics: Anesthetics, Local; Biotransformation; Chromatography, High Pressure Liquid; Humans; Piperidines | 1987 |
Pharmacokinetics of the new local anaesthetic N-[2-(2-Heptyloxyphenylcarbamoyloxy)ethyl]piperidinium chloride in rats and mice.
Topics: Administration, Oral; Anesthetics, Local; Animals; Autoradiography; Brain; Feces; Injections, Intravenous; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1987 |
Carbamate-induced rhythmic activity in the guinea-pig ileum.
Topics: Anesthetics, Local; Animals; Carbamates; Cell Membrane; Colon; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Piperidines | 1986 |
[Study of the gentoxocity of pharmaceutic preparations using rapid methods].
Topics: Benzothiazoles; Escherichia coli; Euglena gracilis; Furazolidone; Mutagenicity Tests; Nitrofurantoin; Nitrofurazone; Piperidines; Salmonella typhimurium; Thiazoles | 1985 |
[Morphologic changes in L-fibroblasts induced by heptacaine and studied by scanning electron microscopy].
Topics: Cell Line; Fibroblasts; Microscopy, Electron, Scanning; Piperidines | 1986 |
[The effect of heptacaine hydrochloride and trimecaine hydrochloride on the ultrastructure of the myocardium].
Topics: Acetanilides; Animals; Heart; Myocardium; Myofibrils; Piperidines; Rats; Trimecaine | 1985 |
Inhibitory effects of pentacaine and some related local anaesthetics on rat hepatic adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Anesthetics, Local; Animals; Carbamates; Colforsin; Glucagon; Glucosides; Guanylyl Imidodiphosphate; Liver; Piperidines; Rats; Structure-Activity Relationship | 1985 |
Perturbation effect of local anaesthetics on synaptosomes: variation with depth of the spin label probe.
Topics: Anesthetics, Local; Animals; Brain; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Membrane Lipids; Phenylcarbamates; Piperidines; Rats; Spin Labels; Synaptosomes | 1984 |
A spin label study of the perturbation effect of tertiary amine anesthetics on brain lipid liposomes and synaptosomes.
Topics: Anesthetics, Local; Animals; Cerebral Cortex; Dibucaine; Electron Spin Resonance Spectroscopy; Intracellular Membranes; Lidocaine; Liposomes; Membrane Lipids; Piperidines; Rats; Spin Labels; Synaptosomes; Tetracaine | 1983 |
[Properties of 3',5' c-AMP phosphodiesterase in the cerebral cortex of guinea pigs and the effect of heptacaine].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anesthetics, Local; Animals; Cerebral Cortex; Guinea Pigs; Piperidines | 1984 |
[Antigenic effect of heptacaine hydrochloride and trimecaine hydrochloride on cells and isolated outer membranes of Escherichia coli 04].
Topics: Acetanilides; Antigens, Bacterial; Cell Membrane; Escherichia coli; Piperidines; Trimecaine | 1984 |
[The effect of intermediate products of synthesis and potential metabolites of heptacaine chloride on mammalian chromosomes].
Topics: Anesthetics, Local; Animals; Chromosome Aberrations; Chromosomes; Cricetinae; Cricetulus; Male; Piperidines | 1984 |
[Effect of heptacaine hydrochloride on mammalian chromosomes].
Topics: Anesthetics, Local; Animals; Cell Nucleus; Chromosomes; Cricetinae; Cricetulus; Piperidines | 1983 |
[Correlation between the antimicrobial activity of quaternary ammonium salts of heptacaine against Staphylococcus aureus and the extraction constant of ion pairs].
Topics: Chemical Phenomena; Chemistry, Physical; Piperidines; Quaternary Ammonium Compounds; Staphylococcus aureus; Structure-Activity Relationship | 1983 |
Effect of the local anesthetic heptacaine hydrochloride on the structured water in model phosphatidylcholine membrane: 2D-NMR and 31P-NMR study.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphorus Isotopes; Piperidines; Temperature; Water | 1983 |
[Biotransformation of heptacaine hydrochloride in vitro].
Topics: Animals; Biotransformation; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Piperidines; Rats; Rats, Inbred Strains | 1984 |
Effect of heptacaine and of some intermediary products obtained during its synthesis on Salmonella typhimurium and Escherichia coli.
Topics: Anesthetics, Local; Escherichia coli; Mutagenicity Tests; Mutagens; Piperidines; Salmonella typhimurium | 1982 |
Changes in lymphoid organs, peripheral blood and in homing of lymphocytes after administration of local anaesthetics.
Topics: Anesthetics, Local; Animals; Carbamates; Cell Movement; Female; Leukocyte Count; Lymphocytes; Lymphoid Tissue; Male; Mice; Organ Size; Piperidines; Trimecaine | 1983 |
Antiarrhythmic activity of heptacaine and some of its derivatives.
Topics: Animals; Anti-Arrhythmia Agents; Digoxin; Epinephrine; Female; Guinea Pigs; Male; Medigoxin; Ouabain; Piperidines; Rats; Structure-Activity Relationship | 1982 |
[Studies of local anesthetics. LXXII. Binding of local anesthetics to a model protein].
Topics: Anesthetics, Local; Animals; Carbamates; Piperidines; Protein Binding; Trimecaine; Wool | 1980 |
[Detection of heptacaine-N-oxide in urine by oscillography and pulse polarography].
Topics: Electrochemistry; Humans; Piperidines; Polarography | 1981 |
In vitro cytotoxicity in rabbit corneal cells of two new local anesthetics--pentacaine and heptacaine.
Topics: Anesthetics, Local; Animals; Carbamates; Cornea; In Vitro Techniques; Piperidines; Proline; Rabbits; Thymidine; Trimecaine | 1981 |
The effect of new local anaesthetics on tracheal and anococcygeal smooth muscle.
Topics: Anal Canal; Anesthetics, Local; Animals; Carbamates; Female; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Trachea | 1981 |
[Determination of the availability of drugs from selected ointment bases by means of in vitro experiments. Part 4: The release of the local anaesthetic heptacaine (author's transl)].
Topics: Anesthetics, Local; Biological Availability; Diffusion; Ointment Bases; Piperidines | 1980 |
Study of local anesthetics. Part 128. HPLC study of the degradation of heptacaine and carbisocaine in urine, human and rabbit serums.
Topics: Anesthetics, Local; Animals; Biodegradation, Environmental; Carbamates; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Piperidines; Rabbits | 1995 |
Biphasic effect of local anesthetic and beta-blocker heptacaine on fluidity of phosphatidylcholine bilayers as detected by ESR spin probe method.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Membrane Fluidity; Molecular Weight; Phosphatidylcholines; Piperidines | 1995 |
Study of local anaesthetics: Part 124. Influence of the ointment bases on the liberation of pentacaine chloride and heptacaine chloride.
Topics: Administration, Topical; Anesthetics, Local; Carbamates; Kinetics; Ointments; Piperidines | 1994 |
[Interactions of surfactants with model and biological membranes. XXII. Spectrophotometric determination of partition coefficient of heptacaine, a local anesthetic, between the phospholipid liposome and water phase].
Topics: Anesthetics, Local; Liposomes; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Piperidines; Scattering, Radiation; Spectrophotometry, Ultraviolet; Surface-Active Agents | 1996 |
Influence of auxiliary substances on the release of heptacaine from the drug form.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Cellulose; Cricetinae; Delayed-Action Preparations; Hypromellose Derivatives; Methylcellulose; Ophthalmic Solutions; Piperidines; Solutions; Time Factors | 1996 |
Interaction of local anesthetic heptacaine homologs with phosphatidylcholine bilayers: spin label ESR study.
Topics: Anesthetics, Local; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Phosphatidylcholines; Piperidines; Spin Labels | 1997 |
Study of local anaesthetics. Part 139. Preformulation study of N-[2-(2-heptyloxyphenylcarbamoyloxy)-ethyl] dimethylammonium chloride.
Topics: Anesthetics, Local; Biological Availability; Chemistry, Pharmaceutical; Glycerol; Piperidines; Propylene Glycol; Solutions; Sorbitol; Surface Tension; Viscosity | 1996 |
Interaction of the local anaesthetic heptacaine with dipalmitoylphosphatidylcholine liposomes: a densimetric study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Biophysical Phenomena; Biophysics; Chemical Phenomena; Chemistry, Physical; Liposomes; Piperidines; Thermodynamics; Water | 1999 |
Thermodynamic study of the local anaesthetic heptacaine. Study of local anaesthetics, Part: 149.
Topics: Algorithms; Anesthetics, Local; Micelles; Piperidines; Temperature; Thermodynamics | 1999 |
[Effect of macromolecular substances on pharmaceutical availability of a potential local anesthetic].
Topics: Anesthetics, Local; Cellulose; Dosage Forms; In Vitro Techniques; Macromolecular Substances; Pharmaceutic Aids; Piperidines; Viscosity | 2000 |
Determination of partition coefficient by the change of main phase transition.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Chemical Phenomena; Chemistry; Permeability; Piperidines; Solubility; Surface Properties; Temperature; Thermodynamics; Water | 2000 |
[Local anesthetics. Part 154: study of micellization of homologs of heptacain chloride].
Topics: Anesthetics, Local; Micelles; Piperidines; Spectrophotometry | 2001 |
[Study of local anesthetics. CLVII. Chromatographic properties of pentacaine, carbisocaine, heptacaine and its 3-, and 4-positional isomers in the RP HPLC system].
Topics: Anesthetics, Local; Carbamates; Chromatography, High Pressure Liquid; Isomerism; Piperidines | 2001 |
Partition of local anesthetic heptacaine homologs between phosphatidylcholine bilayers in unilamellar liposomes and aqueous phase: UV-VIS spectrophotometry study.
Topics: Algorithms; Anesthetics, Local; Chemical Phenomena; Chemistry, Physical; Light; Lipid Bilayers; Liposomes; Nonlinear Dynamics; Phosphatidylcholines; Piperidines; Scattering, Radiation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2002 |
Thermodynamic study of local anesthetics based on heptacainium chloride derivatives. Study of local anesthetics. Part 163.
Topics: Algorithms; Anesthetics, Local; Micelles; Piperidines; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics | 2003 |
Persistent suppression of phagocytosis after prolonged administration of local anesthetics carbisocaine and heptacaine in mouse leukocytes.
Topics: Anesthetics, Local; Animals; Body Weight; Carbamates; Female; Leukocyte Count; Liver; Macrophages; Mice; Mice, Inbred C57BL; Organ Size; Phagocytosis; Piperidines; Spleen | 2005 |
Influence of alcohols on the critical micelle concentration of heptacainium chloride. Study of local anesthetics, part 171.
Topics: Alcohols; Algorithms; Anesthetics, Local; Micelles; Piperidines; Solvents; Surface-Active Agents; Thermodynamics | 2007 |
[Studies on local anesthetics. Part 183: micellization and thermodynamic parameters of heptacainium chloride in the solution of potassium bromide].
Topics: Anesthetics, Local; Bromides; Chemistry, Pharmaceutical; Micelles; Piperidines; Potassium Compounds; Solutions; Thermodynamics | 2008 |
Study of local anaesthetics--Part 196 formulation of the local anaesthetic heptacaine into hydrogel on the basis of chitosan.
Topics: Anesthetics, Local; Chemistry, Pharmaceutical; Chitosan; Drug Compounding; Hydrogel, Polyethylene Glycol Dimethacrylate; Piperidines | 2012 |
[Studies of local anaesthetics: part 205* studies of stability of heptacainium chloride and carbisocainium chloride using an accelerated non-isothermal test].
Topics: Anesthetics, Local; Carbamates; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Piperidines; Sodium Hydroxide; Solutions; Water | 2014 |
[Study of local anaesthetics: Part 206* Micellization of selected of quaternary ammonium salt derived from heptacaine].
Topics: Anesthetics, Local; Hydrophobic and Hydrophilic Interactions; Micelles; Piperidines; Quaternary Ammonium Compounds; Temperature | 2015 |