Compounds > hepsulfam
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hepsulfam and busulfan

hepsulfam has been researched along with busulfan in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, DP; Dengler, WA; Fiebig, HH; Winterhalter, BR1
Cook, C; Gibson, NW; Hincks, JR; Pacheco, DY1
Adlakha, A; Cook, CA; Furmanski, P; Gibson, NW; Hincks, JR; Johnson, CS1
Gibson, NW; Pacheco, DY; Stratton, NK1
Degen, DR; Kuhn, JG; Marshall, MH; Marshall, MV; Roodman, GD; Ross, ME; Von Hoff, DD1
Je, KH; Lee, CS; O'Connor, TR; Son, JK1
Booth, JD; Fang, Q; McManus, FP; Noronha, AM; Pegg, AE; Wilds, CJ1

Other Studies

7 other study(ies) available for hepsulfam and busulfan

ArticleYear
Preclinical activity of hepsulfam and busulfan in solid human tumor xenografts and human bone marrow.
    Anti-cancer drugs, 1992, Volume: 3, Issue:5

    Topics: Animals; Antineoplastic Agents; Bone Marrow Diseases; Busulfan; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraperitoneal; Mice; Mice, Nude; Neoplasm Transplantation; Sulfonic Acids; Transplantation, Heterologous

1992
Mechanisms of toxicity of hepsulfam in human tumor cell lines.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Antineoplastic Agents; Busulfan; Cell Line; Colony-Forming Units Assay; DNA; DNA Damage; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukemia, Experimental; Sulfonic Acids

1990
In vitro studies on the mechanism of action of hepsulfam in chronic myelogenous leukemia patients.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Antineoplastic Agents; Busulfan; Cell Survival; Colony-Forming Units Assay; DNA Damage; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Sulfonic Acids

1990
Comparison of the mechanism of action of busulfan with hepsulfam, a new antileukemic agent, in the L1210 cell line.
    Cancer research, 1989, Sep-15, Volume: 49, Issue:18

    Topics: Animals; Antineoplastic Agents; Busulfan; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Leukemia L1210; Mice; Neoplasm Proteins; Sulfonic Acids; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
In vitro cytotoxicity of hepsulfam against human tumor cell lines and primary human tumor colony forming units.
    Stem cells (Dayton, Ohio), 1993, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Busulfan; Female; Humans; In Vitro Techniques; Male; Neoplastic Stem Cells; Sulfonic Acids; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Hepsulfam induced DNA adducts and its excision repair by bacterial and mammalian 3-methyladenine DNA glycosylases.
    Molecules and cells, 1998, Dec-31, Volume: 8, Issue:6

    Topics: Alkylation; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Binding Sites; Busulfan; Cross-Linking Reagents; DNA; DNA Adducts; DNA Glycosylases; DNA Repair; DNA, Bacterial; Escherichia coli; Humans; N-Glycosyl Hydrolases; Plasmids; Rats; Sulfonic Acids

1998
Synthesis and characterization of an O(6)-2'-deoxyguanosine-alkyl-O(6)-2'-deoxyguanosine interstrand cross-link in a 5'-GNC motif and repair by human O(6)-alkylguanine-DNA alkyltransferase.
    Organic & biomolecular chemistry, 2010, Oct-07, Volume: 8, Issue:19

    Topics: Alkylating Agents; Animals; Busulfan; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Deoxyguanosine; DNA; DNA Repair; Humans; Mutation; Nucleic Acid Denaturation; O(6)-Methylguanine-DNA Methyltransferase; Sulfonic Acids

2010