Page last updated: 2024-08-23

heme and zinc protoporphyrin ix

heme has been researched along with zinc protoporphyrin ix in 88 studies

Research

Studies (88)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (10.23)	18.7374
1990's	25 (28.41)	18.2507
2000's	28 (31.82)	29.6817
2010's	22 (25.00)	24.3611
2020's	4 (4.55)	2.80

Authors

Authors	Studies
Cornelius, CE; Freedland, RA; Rodgers, PA	1
Akatsuka, J; Kaneko, T; Kitajima, H	1
Labbe, RF	1
Labbé, RF; Rettmer, RL	1
Keyes, WR; Kretsch, MJ; Shah, AG; Smith, RG; Turnlund, JR	1
Rodgers, PA; Stevenson, DK; Vreman, HJ	2
Field, PH; Gunter, EW; Parsons, PJ; Stanton, NV	1
Hansen, G; Kremer, A; Kutter, D; Missenard, C	1
Daniel, RF; Kutty, RK; Levin, W; Maines, MD; Ryan, DE	1
Stevenson, DK; Vreman, HJ	1
Albani, J; Alpert, B	1
Bonkovsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR; Smith, EL	1
Corona, D; López-Karpovitch, X; Marín, A; Molina Recio, NY; Piedras, J; Sánchez-Anzaldo, J	1
Kappas, A; Sassa, S; Verger, C	1
Bloomer, JR; Morton, KO; Reuter, RJ; Wehner, JM	1
Luckhurst, CL; Simmonds, PL; Woods, JS	1
Ido, K; Kimura, K; Sato, H	1
Benson, D; Bolgiano, DC; Meyer, D; Price, T; Sayers, M; Slichter, SJ	1
Dailey, HA; Proulx, KL; Woodard, SI	1
Abraham, NG; Dunn, MW; Jiang, S; Kappas, A; Laniado-Schwartzman, M; Levere, RD; Neil, TK; Stoltz, RA	1
Cerami, A; Martiney, JA; Slater, AF	1
Detter, JC; Felgenhauer, J; Graham, EA; Labbe, RF	1
Carlson, TH; Detter, JC; Graham, EA; Labbe, RF; Sodergren, KK	1
Gorman, N; Jacobs, JM; Nichols, C; Sinclair, JF; Sinclair, PR; Walton, HS; Wood, SG	1
Allen, KR; Barth, JH; Nelson, JC; Newton, KE; Westwood, M	1
Burstyn, JN; Serfass, L	1
Argyris, EG; Kay, BK; Paterson, Y; Vanderkooi, JM; Venkateswaran, PS	1
dos Santos, EA; Heimann, JC; Yamaguishi, GA	1
Dewanji, A; Labbé, RF; McLaughlin, K	1
Carlson, TH; Jack, RM; Labb, RF; Origenes, ML; Rettmer, RL	1
Minagawa, H; Miyazaki, G; Morimoto, H; Nakagawa, A; Park, SY; Shibayama, N; Yun, KM	1
Labbé, RF; Stevenson, DK; Vreman, HJ	1
Bast, A; Haenen, GR; Stevenson, DK; Vreman, HJ	1
Kling, PJ; Winzerling, JJ	1
Huang, TJ; Maines, MD; McCoubrey, WK	1
Cooke, RJ; Griffin, IJ; McCormick, KP; Reid, MM	1
Buck, BL; Knopp, RH; Retzlaff, BM; Walden, CE; Wallick, S	1
Juul, SE; Strandjord, TP; Woodrum, DE; Zerzan, JC	1
Flora, SJ; Gupta, M; Kannan, GM; Mehta, A; Satsangi, K	1
Camadro, JM; Dancis, A; Knight, SA; Lesuisse, E; Matzanke, BF; Santos, R	1
Juul, SE	1
Kamiya, N; Nagamune, T; Takeda, S	1
Akins, R; Boyce, R; Gilmour, L; Gratton, K; McLaughlin, T	1
Falzone, CJ; Lecomte, JT; Vu, BC	1
Kling, PJ; Labbé, RF; Lott, DG; Widness, JA; Zimmerman, MB	1
Kling, PJ	1
Juul, SE; McPherson, RJ; Miller, SM	1
Chen, Q; Hirsch, RE	1
Kling, PJ; Lesser, KB; Schoel, SB	1
Berko, A; Cavicchi, M; Fritz, P; Horvath, K; Lamarque, D; Laszlo, F; Posa, A; Varga, C; Whittle, BJ	1
Ambekar, JG; Bhagwat, VR; Das, KK; Dongre, NN; Patil, AJ; Patil, JA	1
Blohowiak, SE; Kleven, KJ; Kling, PJ	1
Buchanan, LH; Counter, SA; Ortega, F; Rifai, N; Shannon, MW	1
Buchanan, LH; Counter, SA; Ortega, F	2
Baumann-Blackmore, NL; Blohowiak, SE; Carlton, DP; Chen, ME; Crenshaw, TD; Georgieff, MK; Kling, PJ; Repyak, KS	1
Baumann-Blackmore, NL; Blohowiak, SE; Goetz, E; Kling, PJ; Zaka, O	1
Ashokan, K; Chottray, GP; Colah, RB; Ghosh, K; Italia, Y; Jain, D; Kaul, R; Mohanty, D; Mukherjee, MB; Muthuswamy, V; Shukla, DK; Wadia, M	1
Anstey, AV; Badminton, MN; Beaumont, C; Corrigall, AV; Deybach, JC; Ducamp, S; Elder, GH; Gouya, L; Grandchamp, B; Hift, RJ; Holme, SA; Ma, Y; Marsden, JT; Meissner, PN; Mieli-Vergani, G; Parker, M; Puy, H; Whatley, SD	1
Janousek, S; Janousek, SJ; Jirova, D; Kejlova, K; Rosa, L	1
Hoffmann, LS; Keim, Y; Schaefer, S; Schmidt, HH; Schmidt, PM; Stasch, JP	1
Arihara, K; Ishikawa, S; Itoh, M; Ohata, M; Tamaki, S	1
Hattori, A; Hayashi, N; Hioki, S; Nishimura, T; Odagiri, H; Okui, J; Uemura, J; Wakamatsu, J	1
Biesalski, HK; Breusing, N; Flaccus, A; Grimm, S; Grune, T; Mvondo, D	1
Brugna, M; Hederstedt, L; Tasse, L	1
Chau, TT; Ishigaki, M; Kataoka, T; Taketani, S	1
Alves-Filho, JC; Barja-Fidalgo, C; Cunha, FQ; Curti, C; Czaikoski, PG; Dal-Secco, D; Freitas, A; Nascimento, DC; Pestana, CR; Sônego, F; Spiller, F; Suavinha, MM; Trevelin, SC	1
Ibrahim, SM; Nakajima, H; Naruta, Y; Ohta, T; Ramanathan, K; Takatani, N; Watanabe, Y	1
Du, G; Fan, Y; Fukuda, Y; Lynch, J; Nachagari, D; Potter, PM; Rehg, JE; Schuetz, JD; Sun, D; Tsurkan, L; Ulrich, DL; Wang, Y	1
Cheng, CF; Johnson, DB; Juul, SE; Zerzan, JC	1
Miller, SM	1
Buchanan, LH; Collaguaso, MA; Coronel Parra, AM; Counter, SA; Hoover, PN; Jacobs, AB; Ortega, F; Rifai, N	1
Banerjee, S; Burris, TP; Hughes, TS; Kojetin, DJ; Matta-Camacho, E; Solt, LA; Wang, Y	1
Bacsik-Campbell, ME; Coe, CL; Dosch, NC; Guilbert, TW; Kling, PJ; Weigert, R	1
Armony-Sivan, R; Clark, KM; Ji, C; Kaciroti, N; Lozoff, B; Richards, B; Shao, J; Zhu, B	1
Chollet, S; De Maere, H; De Mey, E; Dewulf, L; Fraeye, I; Michiels, C; Paelinck, H	1
Abbink, M; Akkermans, MD; Boersma, B; Brus, F; de Waal, CG; Hudig, F; Rövekamp, WW; Uijterschout, L; van Goudoever, JB; Vos, P	1
Denton, C; German, K; Grelli, KN; Juul, SE; Lee, G; Vu, PT	1
Arnau, J; Bou, R; Fulladosa, E; Llauger, M	1
Ghadiri Khozroughi, A; Kroh, LW; Rawel, H; Schlüter, O	1
Hennig, G; Holdt, LM; Homann, C; Koletzko, B; Maier, F; Sroka, R; Stepp, H; Vogeser, M	1
Hayashi, T; Kajihara, R; Oohora, K	1
Bernad, S; Derrien, V; Lei, R; Miksovska, J; Santiago Estevez, MJ; Sebban, P; Tangar, A	1
Bangirana, P; Cusick, SE; Georgieff, MK; Hickson, M; John, CC; Kroupina, M; Nakasujja, N; Opoka, RO; Ssemata, AS; Ssenkusu, JM	1
Bahr, TM; Comstock, BA; German, KR; Heagerty, PJ; Juul, SE; Mayock, DE; Parikh, P; Whittington, D	1
Choi, KR; Lee, SY; Yu, HE	1
Abe, H; Hayakawa, T; Kumura, H; Wakamatsu, JI; Wang, HC; Zhai, Y	1

Reviews

1 review(s) available for heme and zinc protoporphyrin ix

Article	Year
Zinc protoporphyrin: A metabolite with a mission. Clinical chemistry, 1999, Volume: 45, Issue:12 Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Hyperbilirubinemia; Lead Poisoning; Metalloporphyrins; Protoporphyrins	1999

Trials

8 trial(s) available for heme and zinc protoporphyrin ix

Article	Year
Milk's effect on the bioavailability of iron from cereal-based diets in young women by use of in vitro and in vivo methods. The American journal of clinical nutrition, 1990, Volume: 52, Issue:2 Topics: Absorption; Adult; Animals; Biological Availability; Diet; Edible Grain; Feces; Female; Ferritins; Hematocrit; Heme; Hemoglobins; Humans; Iron; Milk; Protoporphyrins; Random Allocation	1990
Iron and zinc status of women and men who followed cholesterol-lowering diets. Journal of the American Dietetic Association, 1998, Volume: 98, Issue:2 Topics: Adult; Analysis of Variance; Cholesterol; Cholesterol, Dietary; Diet Records; Diet, Fat-Restricted; Female; Hematocrit; Heme; Humans; Iron; Longitudinal Studies; Male; Menopause; Prospective Studies; Protoporphyrins; Zinc	1998
Enterally dosed recombinant human erythropoietin does not stimulate erythropoiesis in neonates. The Journal of pediatrics, 2003, Volume: 143, Issue:3 Topics: Administration, Oral; Blood Transfusion; Enteral Nutrition; Enzyme Inhibitors; Erythropoiesis; Erythropoietin; Hematocrit; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Prospective Studies; Protoporphyrins; Recombinant Proteins; Reticulocyte Count; Time Factors	2003
Iron sulfate supplementation decreases zinc protoporphyrin to heme ratio in premature infants. The Journal of pediatrics, 2006, Volume: 148, Issue:1 Topics: Age Factors; Dietary Supplements; Dose-Response Relationship, Drug; Female; Ferritins; Ferrous Compounds; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Iron; Isoprostanes; Male; Pilot Projects; Prospective Studies; Protoporphyrins; Reticulocytes; Treatment Outcome	2006
Iron deficiency anaemia in sickle cell disorders in India. The Indian journal of medical research, 2008, Volume: 127, Issue:4 Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Anemia, Sickle Cell; Child; Female; Heme; Humans; India; Iron; Iron Deficiencies; Male; Prevalence; Protoporphyrins	2008
Iron supplementation in premature infants using the zinc protoporphyrin to heme ratio: short- and long-term outcomes. Journal of perinatology : official journal of the California Perinatal Association, 2013, Volume: 33, Issue:9 Topics: Anemia, Iron-Deficiency; Dietary Supplements; Female; Ferrous Compounds; Follow-Up Studies; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Prospective Studies; Protoporphyrins; Time Factors; Treatment Outcome	2013
Delayed iron does not alter cognition or behavior among children with severe malaria and iron deficiency. Pediatric research, 2020, Volume: 88, Issue:3 Topics: Anemia, Iron-Deficiency; Attention; Behavior; Child Behavior Disorders; Child, Preschool; Cognition; Drug Administration Schedule; Emotions; Female; Follow-Up Studies; Heme; Humans; Infant; Iron; Iron Deficiencies; Malaria, Cerebral; Male; Memory; Protoporphyrins; Uganda	2020
Do Extremely Low Gestational Age Neonates Regulate Iron Absorption via Hepcidin? The Journal of pediatrics, 2022, Volume: 241 Topics: Biomarkers; Creatinine; Erythropoietin; Ferritins; Heme; Hepcidins; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Iron; Protoporphyrins; Retrospective Studies	2022

Other Studies

79 other study(ies) available for heme and zinc protoporphyrin ix

Article	Year
Bilirubin production and conjugation from newly formed heme in isolated rat hepatocytes. The International journal of biochemistry, 1992, Volume: 24, Issue:9 Topics: Aminolevulinic Acid; Animals; Bile Pigments; Bilirubin; Cells, Cultured; Cobalt; Heme; Hemin; Kinetics; Liver; Male; Metalloporphyrins; Protoporphyrins; Rats; Rats, Sprague-Dawley	1992
[The measurement of erythrocyte zinc protoporphyrin/heme ratio in various anemias in childhood]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:9 Topics: Anemia; Anemia, Hypochromic; Child; Child, Preschool; Erythrocytes; Hematologic Diseases; Heme; Humans; Protoporphyrins	1992
Zinc protoporphyrin/heme ratio as an indicator of marrow iron stores. American journal of clinical pathology, 1991, Volume: 95, Issue:5 Topics: Bone Marrow; Heme; Humans; Iron; Protoporphyrins	1991
Measurement of zinc protoporphyrin with the ProtoFluor-Z System. Clinical chemistry, 1990, Volume: 36, Issue:4 Topics: Fluorometry; Heme; Humans; Porphyrins; Protoporphyrins; Spectrometry, Fluorescence	1990
Zinc protoporphyrin administration for suppression of increased bilirubin production by iatrogenic hemolysis in rhesus neonates. The Journal of pediatrics, 1990, Volume: 117, Issue:2 Pt 1 Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemolysis; Humans; Infant, Newborn; Jaundice, Neonatal; Macaca mulatta; Mixed Function Oxygenases; Porphyrins; Protoporphyrins	1990
Heme catabolism in rhesus neonates inhibited by zinc protoporphyrin. Developmental pharmacology and therapeutics, 1990, Volume: 14, Issue:4 Topics: Animals; Animals, Newborn; Bilirubin; Blood Gas Analysis; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Indicators and Reagents; Liver; Macaca mulatta; Porphyrins; Protoporphyrins	1990
Empirically determined lead-poisoning screening cutoff for the Protofluor-Z hematofluorometer. Clinical chemistry, 1989, Volume: 35, Issue:10 Topics: Erythrocytes; Fluorometry; Hematocrit; Heme; Humans; Lead Poisoning; Mass Screening; Mathematics; Pediatrics; Porphyrins; Protoporphyrins; Spectrometry, Fluorescence	1989
Vanadium induced impairment of haem synthesis. British journal of industrial medicine, 1989, Volume: 46, Issue:10 Topics: Heme; Humans; Lead; Luxembourg; Metallurgy; Occupational Diseases; Protoporphyrins; Vanadium	1989
Rat liver cytochrome P-450b, P-420b, and P-420c are degraded to biliverdin by heme oxygenase. Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2 Topics: Animals; Bilirubin; Biliverdine; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Heme Oxygenase (Decyclizing); Isoenzymes; Liver; Metalloporphyrins; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Protoporphyrins; Rats; Spectrophotometry	1988
Carbon monoxide generation from tin- and zinc-protoporphyrin by tissue homogenates. Biochemical and biophysical research communications, 1987, Oct-14, Volume: 148, Issue:1 Topics: Animals; Carbon Monoxide; Female; Heme; Intestinal Mucosa; Kidney; Kinetics; Liver; Metalloporphyrins; Organ Specificity; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spleen	1987
Fluctuation domains in myoglobin. Fluorescence quenching studies. European journal of biochemistry, 1987, Jan-02, Volume: 162, Issue:1 Topics: Heme; Myoglobin; Oxygen; Protoporphyrins; Spectrometry, Fluorescence	1987
Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide. The Biochemical journal, 1984, Sep-01, Volume: 222, Issue:2 Topics: Acetamides; Allylisopropylacetamide; Animals; Apoenzymes; Cytochrome P-450 Enzyme System; Heme; Immunoelectrophoresis; In Vitro Techniques; Liver; Male; Phenobarbital; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spectrophotometry	1984
[Chronic lead exposure. Its repercussion on indicators of heme synthesis and iron metabolism]. Sangre, 1983, Volume: 28, Issue:6 Topics: Adolescent; Adult; Aminolevulinic Acid; Child; Child, Preschool; Female; Food Handling; Heme; Humans; Iron; Lead; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Protoporphyrins	1983
Growth-promoting effects of iron- and cobalt- protoporphyrins on cultured embryonic cells. Journal of cellular physiology, 1983, Volume: 116, Issue:2 Topics: Animals; Cell Adhesion; Cell Division; Cells, Cultured; Chick Embryo; Fibroblasts; Heme; Hemin; Kinetics; Liver; Metalloporphyrins; Muscles; Porphyrins; Protoporphyrins	1983
Enzymatic formation of zinc-protoporphyrin by rat liver and its potential effect on hepatic heme metabolism. Gastroenterology, 1983, Volume: 85, Issue:3 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Depression, Chemical; Enzyme Induction; Feedback; Ferrochelatase; Heme; Liver; Lyases; Male; Mitochondria, Liver; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Stimulation, Chemical	1983
Quantitative evaluation of heme biosynthetic pathway parameters as biomarkers of low-level lead exposure in rats. Journal of toxicology and environmental health, 1995, Volume: 44, Issue:3 Topics: Analysis of Variance; Animals; Biomarkers; Coproporphyrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Erythrocytes; Heme; Lead; Lead Poisoning; Male; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Inbred F344; Spectrophotometry, Atomic; Water Pollutants, Chemical	1995
Simultaneous separation and quantification of free and metal-chelated protoporphyrins in blood by three-dimensional HPLC. Clinical chemistry, 1994, Volume: 40, Issue:7 Pt 1 Topics: Adult; Chromatography, High Pressure Liquid; Erythrocytes; Heme; Hemoglobins; Humans; Kinetics; Lead Poisoning; Male; Methanol; Propylamines; Protoporphyrins; Solvents; Spectrometry, Fluorescence; Water	1994
Red cell collection by apheresis technology. Transfusion, 1993, Volume: 33, Issue:10 Topics: Adolescent; Adult; Aged; Blood Component Removal; Blood Donors; Blood Transfusion; Erythrocyte Transfusion; Female; Ferritins; Heme; Humans; Iron; Male; Middle Aged; Protoporphyrins	1993
In situ conversion of coproporphyrinogen to heme by murine mitochondria: terminal steps of the heme biosynthetic pathway. Protein science : a publication of the Protein Society, 1993, Volume: 2, Issue:7 Topics: Animals; Coproporphyrinogen Oxidase; Coproporphyrinogens; Ferrochelatase; Flavoproteins; Heme; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Mitochondria, Liver; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Protoporphyrinogen Oxidase; Protoporphyrins; Zinc	1993
Modulation of corneal heme oxygenase expression by oxidative stress agents. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Fall, Volume: 11, Issue:3 Topics: Animals; Antioxidants; Blotting, Northern; Cell Line; Cells, Cultured; Cornea; Cytokines; Enzyme Induction; Enzyme Inhibitors; Epithelium; Glutathione; Glutathione Disulfide; Heme; Heme Oxygenase (Decyclizing); Metals; Oxidative Stress; Protoporphyrins; Rabbits; RNA, Messenger; Vitamin B 12	1995
Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait. Molecular medicine (Cambridge, Mass.), 1996, Volume: 2, Issue:2 Topics: Animals; beta-Thalassemia; Deuteroporphyrins; Enzyme Inhibitors; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Humans; Immunity, Innate; Kinetics; Malaria, Falciparum; Metalloporphyrins; Pigments, Biological; Plasmodium falciparum; Protoporphyrins	1996
Elevated zinc protoporphyrin associated with thalassemia trait and hemoglobin E. The Journal of pediatrics, 1996, Volume: 129, Issue:1 Topics: Adolescent; Adult; alpha-Thalassemia; beta-Thalassemia; Female; Heme; Hemoglobin E; Humans; Male; Middle Aged; Protoporphyrins	1996
Delayed bottle weaning and iron deficiency in southeast Asian toddlers. The Western journal of medicine, 1997, Volume: 167, Issue:1 Topics: Asia, Southeastern; Bottle Feeding; Child, Preschool; Cultural Characteristics; Female; Heme; Humans; Infant; Iron; Iron Deficiencies; Male; Metalloporphyrins; Poverty; Protoporphyrins; Statistics, Nonparametric; Washington	1997
Formation of zinc protoporphyrin in cultured hepatocytes: effects of ferrochelatase inhibition, iron chelation or lead. Toxicology, 1998, Feb-06, Volume: 125, Issue:2-3 Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Ferrochelatase; Heme; Iron Chelating Agents; Lead; Liver; Male; Protoporphyrins; Rats; Rats, Inbred F344	1998
The ratio of erythrocyte zinc-protoporphyrin to protoporphyrin IX in disease and its significance in the mechanism of lead toxicity on haem synthesis. Annals of clinical biochemistry, 1998, Volume: 35 ( Pt 3) Topics: Adult; Erythrocytes; Female; Heme; Humans; Lead Poisoning; Male; Protoporphyrins; Reproducibility of Results; Sensitivity and Specificity	1998
Effect of heme oxygenase inhibitors on soluble guanylyl cyclase activity. Archives of biochemistry and biophysics, 1998, Nov-01, Volume: 359, Issue:1 Topics: Animals; Cattle; Enzyme Activation; Enzyme Inhibitors; Guanosine Triphosphate; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Metalloporphyrins; Protein Binding; Protoporphyrins; Substrate Specificity	1998
The connection domain is implicated in metalloporphyrin binding and inhibition of HIV reverse transcriptase. The Journal of biological chemistry, 1999, Jan-15, Volume: 274, Issue:3 Topics: Amino Acid Sequence; Bacteriophage M13; Binding Sites; Dimerization; Drug Design; Enzyme Inhibitors; Heme; HIV Reverse Transcriptase; Humans; Metalloporphyrins; Models, Molecular; Molecular Sequence Data; Peptide Library; Protein Conformation; Protoporphyrins; RNA-Directed DNA Polymerase	1999
Effect of the heme/heme oxygenase pathway on the relationship between salt consumption and blood pressure. Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2 Topics: Animals; Blood Pressure; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Male; Protoporphyrins; Rats; Rats, Wistar; Sodium, Dietary	1998
Observations on the zinc protoporphyrin/heme ratio in whole blood. Clinical chemistry, 1999, Volume: 45, Issue:1 Topics: Blood Specimen Collection; Heme; Hemolysis; Humans; Metalloporphyrins; Protoporphyrins	1999
Zinc protoporphyrin/heme ratio for diagnosis of preanemic iron deficiency. Pediatrics, 1999, Volume: 104, Issue:3 Topics: Adolescent; Age Factors; Anemia, Iron-Deficiency; Child; Child, Preschool; Enzyme Inhibitors; Female; Ferritins; Hematologic Tests; Heme; Heme Oxygenase (Decyclizing); Humans; Infant; Iron; Iron Deficiencies; Male; Protoporphyrins; Regression Analysis; Sensitivity and Specificity; Sex Factors; Transferrin	1999
Magnesium(II) and zinc(II)-protoporphyrin IX's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme. Journal of molecular biology, 1999, Oct-08, Volume: 292, Issue:5 Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Oxygen; Phytic Acid; Protein Structure, Quaternary; Protein Structure, Tertiary; Protons; Protoporphyrins; Spectrophotometry; Thermodynamics	1999
Reduction of the NO-mediated response in the rat aorta by metalloporphyrins. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:6 Topics: Animals; Aorta; Heme; Male; Metalloporphyrins; Methacholine Chloride; Muscarinic Agonists; Nitric Oxide; Phenylephrine; Protoporphyrins; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents	2000
Iron-deficient erythropoiesis in premature infants measured by blood zinc protoporphyrin/heme. The Journal of pediatrics, 2001, Volume: 139, Issue:1 Topics: Blood Cell Count; Enzyme Inhibitors; Erythropoiesis; Female; Ferritins; Heme; Humans; Infant, Newborn; Infant, Premature, Diseases; Iron Deficiencies; Male; Protoporphyrins	2001
Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs. Antioxidants & redox signaling, 2001, Volume: 3, Issue:4 Topics: Amino Acid Motifs; Amino Acid Substitution; Catalytic Domain; Circular Dichroism; Cysteine; Heme; Heme Oxygenase (Decyclizing); Humans; Hydrogen-Ion Concentration; Metalloporphyrins; Peptide Fragments; Proline; Protein Binding; Protoporphyrins; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents	2001
Zinc protoporphyrin/haem ratio and plasma ferritin in preterm infants. Archives of disease in childhood. Fetal and neonatal edition, 2002, Volume: 87, Issue:1 Topics: Female; Ferritins; Growth; Heme; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Prospective Studies; Protoporphyrins	2002
Zinc protoporphyrin/heme as an indicator of iron status in NICU patients. The Journal of pediatrics, 2003, Volume: 142, Issue:3 Topics: Biomarkers; Blood Cell Count; Erythrocyte Transfusion; Erythropoietin; Ferrous Compounds; Gestational Age; Heme; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Iron Deficiencies; Protoporphyrins; Recombinant Proteins; Reference Values; Risk Factors	2003
Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2003, Volume: 134, Issue:3 Topics: Aluminum; Animals; Brain; Chelating Agents; Citric Acid; Drug Synergism; Edetic Acid; Glutathione; Heme; Male; Oxidative Stress; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2003
Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1). Human molecular genetics, 2003, Apr-15, Volume: 12, Issue:8 Topics: Cytochromes; Ferrochelatase; Frataxin; Fungal Proteins; Gene Deletion; Genes, Fungal; Heme; Iron; Iron-Binding Proteins; Mitochondria; Protoporphyrins; Saccharomyces cerevisiae; Suppression, Genetic	2003
Rational design of a protein-based molecular device consisting of blue fluorescent protein and zinc protoporphyrin IX incorporated into a cytochrome b562 scaffold. Biotechnology letters, 2004, Volume: 26, Issue:2 Topics: Cytochrome b Group; Energy Transfer; Escherichia coli Proteins; Green Fluorescent Proteins; Luminescent Proteins; Models, Molecular; Protein Conformation; Protein Engineering; Protoporphyrins; Recombinant Fusion Proteins; Spectrometry, Fluorescence	2004
Exogenous metalloporphyrins alter the organization and function of cultured neonatal rat heart cells via modulation of heme oxygenase activity. Journal of cellular physiology, 2004, Volume: 201, Issue:1 Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Myocardial Contraction; Myocytes, Cardiac; Oligonucleotides; Protoporphyrins; Rats; Sarcomeres	2004
Structural and dynamic properties of Synechocystis sp. PCC 6803 Hb revealed by reconstitution with Zn-protoporphyrin IX. Journal of inorganic biochemistry, 2005, Volume: 99, Issue:8 Topics: Crystallography, X-Ray; Heme; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Structure, Tertiary; Protoporphyrins; Synechocystis; Temperature	2005
Erythrocyte zinc protoporphyrin is elevated with prematurity and fetal hypoxemia. Pediatrics, 2005, Volume: 116, Issue:2 Topics: Erythrocyte Indices; Erythrocytes; Erythropoietin; Female; Ferritins; Fetal Blood; Fetal Diseases; Fetal Growth Retardation; Gestational Age; Heme; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Insulin; Pregnancy; Pregnancy in Diabetics; Protoporphyrins; Reticulocyte Count	2005
The zinc protoporphyrin/heme ratio in premature infants: has it found its place? The Journal of pediatrics, 2006, Volume: 148, Issue:1 Topics: Heme; Humans; Infant, Newborn; Infant, Premature; Iron; Iron Deficiencies; Predictive Value of Tests; Protoporphyrins; Reticulocytes	2006
A direct and simultaneous detection of zinc protoporphyrin IX, free protoporphyrin IX, and fluorescent heme degradation product in red blood cell hemolysates. Free radical research, 2006, Volume: 40, Issue:3 Topics: Animals; Erythrocytes; Fluorescence; Heme; Hemoglobin E; Hydrogen Peroxide; Mice; Mice, Transgenic; Oxidants; Protoporphyrins	2006
Elevated zinc protoporphyrin/heme ratios in umbilical cord blood after diabetic pregnancy. Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:11 Topics: Adult; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Fetal Blood; Heme; Humans; Iron Deficiencies; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, Third; Protoporphyrins; Regression Analysis; Retrospective Studies	2006
Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat. European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3 Topics: Animals; Bilirubin; Blotting, Western; Cadmium Chloride; Colitis, Ulcerative; Disease Models, Animal; Enzyme Inhibitors; Heme; Heme Oxygenase-1; Male; Metalloporphyrins; Peroxidase; Protoporphyrins; Rats; Rats, Wistar; Up-Regulation	2007
Biochemical aspects of lead exposure in silver jewelry workers in western Maharashtra (India). Journal of basic and clinical physiology and pharmacology, 2006, Volume: 17, Issue:4 Topics: Adult; Catalase; Ceruloplasmin; Enzymes; Heme; Humans; India; Lead; Lipid Peroxides; Male; Malondialdehyde; Middle Aged; Occupational Exposure; Porphobilinogen; Porphobilinogen Synthase; Protoporphyrins; Reactive Oxygen Species; Silver; Superoxide Dismutase	2006
Zinc protoporphyrin/heme in large-for-gestation newborns. Neonatology, 2007, Volume: 92, Issue:2 Topics: Birth Weight; Cohort Studies; Fetal Blood; Gestational Age; Heme; Humans; Infant, Newborn; Prospective Studies; Protoporphyrins	2007
Comparative analysis of zinc protoporphyrin and blood lead levels in lead-exposed Andean children. Clinical biochemistry, 2007, Volume: 40, Issue:11 Topics: Adolescent; Age Distribution; Child; Child, Preschool; Ecuador; Female; Heme; Humans; Infant; Lead; Lead Poisoning; Male; Protoporphyrins	2007
Zinc protoporphyrin levels, blood lead levels and neurocognitive deficits in Andean children with chronic lead exposure. Clinical biochemistry, 2008, Volume: 41, Issue:1-2 Topics: Adolescent; Case-Control Studies; Child; Cognition; Cognition Disorders; Ecuador; Environmental Exposure; Female; Heme; Humans; Lead; Lead Poisoning, Nervous System, Childhood; Male; Protoporphyrins; Time Factors	2008
Reticulocyte enrichment of zinc protoporphyrin/heme discriminates impaired iron supply during early development. Pediatric research, 2008, Volume: 64, Issue:1 Topics: Age Factors; Anemia, Iron-Deficiency; Anemia, Neonatal; Animals; Animals, Newborn; Animals, Suckling; Biomarkers; Erythropoiesis; Female; Fetal Blood; Heme; Humans; Infant, Newborn; Iron; Predictive Value of Tests; Pregnancy; Pregnancy in Diabetics; Protoporphyrins; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Reticulocytes; Severity of Illness Index	2008
Cord blood zinc protoporphyrin/heme ratio in minority neonates at risk for iron deficiency. The Journal of pediatrics, 2008, Volume: 153, Issue:1 Topics: Anemia, Iron-Deficiency; Black or African American; C-Reactive Protein; Case-Control Studies; Female; Ferritins; Fetal Blood; Heme; Hispanic or Latino; Humans; Infant, Newborn; Iron Deficiencies; Male; Neonatal Screening; Protoporphyrins; Risk	2008
C-terminal deletions in the ALAS2 gene lead to gain of function and cause X-linked dominant protoporphyria without anemia or iron overload. American journal of human genetics, 2008, Volume: 83, Issue:3 Topics: 5-Aminolevulinate Synthetase; Chromosomes, Human, X; Erythrocytes; Female; Heme; Humans; Male; Mutation; Porphyrias, Hepatic; Protoporphyrins	2008
Oxidative stress may modify zinc protoporphyrin/heme ratio in hematofluorometry. International journal of laboratory hematology, 2010, Volume: 32, Issue:1 Pt 2 Topics: Erythrocytes; False Positive Reactions; Fluorometry; Heme; Humans; Oxidative Stress; Protoporphyrins	2010
Neurocognitive screening of lead-exposed andean adolescents and young adults. Journal of toxicology and environmental health. Part A, 2009, Volume: 72, Issue:10 Topics: Adolescent; Attention; Child; Cognition; Ecuador; Female; Heme; Humans; Lead; Lead Poisoning, Nervous System; Male; Memory; Neuropsychological Tests; Occupational Exposure; Protoporphyrins; Psychometrics; Space Perception; Visual Perception; Wechsler Scales; Young Adult	2009
Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation. British journal of pharmacology, 2009, Volume: 157, Issue:5 Topics: Aequorin; Animals; Benzoates; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Enzyme Stability; Genes, Reporter; Guanylate Cyclase; Heme; Molecular Structure; Mutation; ortho-Aminobenzoates; Oxadiazoles; Oxidation-Reduction; Protoporphyrins; Pyrazoles; Pyridines; Quinoxalines; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Structure-Activity Relationship; Sulfonamides; Swine; Transfection	2009
Heme induces DNA damage and hyperproliferation of colonic epithelial cells via hydrogen peroxide produced by heme oxygenase: a possible mechanism of heme-induced colon cancer. Molecular nutrition & food research, 2010, Volume: 54, Issue:8 Topics: Caco-2 Cells; Catalase; Cell Proliferation; Cell Survival; Colonic Neoplasms; DNA Damage; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Neoplastic; Heme; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Interleukin-8; Meat; Osmolar Concentration; Oxidative Stress; Protoporphyrins; Risk Factors; RNA, Messenger	2010
Formation of zinc protoporphyrin IX in Parma-like ham without nitrate or nitrite. Animal science journal = Nihon chikusan Gakkaiho, 2009, Volume: 80, Issue:2 Topics: Animals; Enzyme Inhibitors; Food Coloring Agents; Food Handling; Food Technology; Heme; Meat Products; Nitrates; Nitrites; Oxidation-Reduction; Protoporphyrins; Sodium Chloride, Dietary; Swine	2009
Light-induced cytotoxicity after aminolevulinic acid treatment is mediated by heme and not by iron. Journal of photochemistry and photobiology. B, Biology, 2010, Apr-02, Volume: 99, Issue:1 Topics: Aminolevulinic Acid; Cell Line, Tumor; Deferoxamine; Heme; Heme Oxygenase-1; Humans; Iron; Iron Chelating Agents; Light; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Reactive Oxygen Species	2010
In vivo production of catalase containing haem analogues. The FEBS journal, 2010, Volume: 277, Issue:12 Topics: Catalase; Cobalt; Enterococcus faecalis; Gallium; Heme; Hemeproteins; Metalloporphyrins; Protoporphyrins	2010
Porcine ferrochelatase: the relationship between iron-removal reaction and the conversion of heme to Zn-protoporphyrin. Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:7 Topics: Amino Acid Sequence; Animals; Biocatalysis; Cattle; Cloning, Molecular; DNA, Complementary; Ferrochelatase; Heme; Humans; Iron; Kinetics; Liver; Mice; Mitochondria; Molecular Sequence Data; Muscles; Protoporphyrins; Rats; Swine	2010
Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis. Shock (Augusta, Ga.), 2011, Volume: 35, Issue:6 Topics: Animals; Bilirubin; Cecum; Heme; Heme Oxygenase (Decyclizing); Hemin; Inflammation; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neutrophil Infiltration; Neutrophils; Protoporphyrins; Receptors, Interleukin-8B; Sepsis	2011
Cytochrome c(552) from Thermus thermophilus engineered for facile substitution of prosthetic group. Biochemistry, 2011, Nov-15, Volume: 50, Issue:45 Topics: Amino Acid Substitution; Bacterial Proteins; Base Sequence; Cysteine; Cytochrome c Group; DNA Primers; Heme; Mutagenesis, Site-Directed; Protein Engineering; Protoporphyrins; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Thermus thermophilus	2011
ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. The Journal of biological chemistry, 2012, Apr-13, Volume: 287, Issue:16 Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Coproporphyrins; Erythropoiesis; Female; Gene Expression; Heme; Kruppel-Like Transcription Factors; Mice; Mice, Knockout; Mitochondria; Oxidants; Oxidative Stress; Phenylhydrazines; Porphyrins; Protoporphyrins	2012
Zinc protoporphyrin-to-heme ratios in high-risk and preterm infants. The Journal of pediatrics, 2012, Volume: 161, Issue:1 Topics: Female; Heme; Humans; Infant, Newborn; Infant, Premature; Male; Prospective Studies; Protoporphyrins; Risk Factors	2012
Declining blood lead and zinc protoporphyrin levels in Ecuadorian Andean children. Clinical biochemistry, 2013, Volume: 46, Issue:13-14 Topics: Child; Ecuador; Female; Heme; Humans; Lead; Lead Poisoning; Male; Occupational Exposure; Protoporphyrins	2013
Structure of REV-ERBβ ligand-binding domain bound to a porphyrin antagonist. The Journal of biological chemistry, 2014, Jul-18, Volume: 289, Issue:29 Topics: Amino Acid Sequence; Crystallography, X-Ray; HEK293 Cells; Heme; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nuclear Receptor Subfamily 1, Group D, Member 1; Peptide Fragments; Porphyrins; Protein Binding; Protein Structure, Tertiary; Protoporphyrins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Repressor Proteins	2014
Maternal pregnancy weight gain and cord blood iron status are associated with eosinophilia in infancy. Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:8 Topics: Adult; Anemia, Iron-Deficiency; Eosinophilia; Female; Ferritins; Fetal Blood; Heme; Humans; Infant; Infant, Newborn; Iron; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Protoporphyrins; Risk Factors; Weight Gain	2015
Iron deficiency (ID) at both birth and 9 months predicts right frontal EEG asymmetry in infancy. Developmental psychobiology, 2016, Volume: 58, Issue:4 Topics: Electroencephalography; Female; Ferritins; Fetal Blood; Frontal Lobe; Heme; Humans; Infant; Infant, Newborn; Iron Deficiencies; Male; Protoporphyrins	2016
Formation of naturally occurring pigments during the production of nitrite-free dry fermented sausages. Meat science, 2016, Volume: 114 Topics: Animals; Color; Fermentation; Heme; Humans; Hydrogen-Ion Concentration; Meat Products; Nitrates; Nitrites; Protoporphyrins; Zinc	2016
Zinc protoporphyrin/heme ratio as parameter of iron status in moderately preterm infants: natural course and associations in the first 4 months. Journal of perinatology : official journal of the California Perinatal Association, 2017, Volume: 37, Issue:6 Topics: Anemia, Iron-Deficiency; Female; Ferritins; Gestational Age; Hematologic Tests; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Iron; Iron Deficiencies; Linear Models; Male; Netherlands; Prospective Studies; Protoporphyrins; ROC Curve	2017
Zinc Protoporphyrin-to-Heme Ratio and Ferritin as Measures of Iron Sufficiency in the Neonatal Intensive Care Unit. The Journal of pediatrics, 2018, Volume: 194 Topics: Biomarkers; Erythrocyte Transfusion; Erythropoietin; Female; Ferritins; Heme; Hospitalization; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Iron; Male; Protoporphyrins; Retrospective Studies; Sepsis	2018
Zinc-protoporphyrin content in commercial Parma hams is affected by proteolysis index and marbling. Meat science, 2018, Volume: 139 Topics: Adipose Tissue; Animals; Color; Heme; Meat Products; Proteins; Proteolysis; Protoporphyrins; Sodium Chloride, Dietary; Swine	2018
Assessment of the bacterial impact on the post-mortem formation of zinc protoporphyrin IX in pork meat. Food chemistry, 2018, Aug-01, Volume: 256 Topics: Animals; Back Muscles; Ferrochelatase; Heme; Meat; Protoporphyrins; Pseudomonas fluorescens; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine	2018
Non-invasive measurement of erythrocyte zinc protoporphyrin in children. Pediatric research, 2019, Volume: 85, Issue:3 Topics: Anemia, Iron-Deficiency; Child, Preschool; Erythrocytes; Feasibility Studies; Female; Ferritins; Fluorescence; Heme; Hospitalization; Humans; Infant; Lip; Male; Prospective Studies; Protoporphyrins; Spectrometry, Fluorescence	2019
Photoinduced electron transfer within supramolecular hemoprotein co-assemblies and heterodimers containing Fe and Zn porphyrins. Journal of inorganic biochemistry, 2019, Volume: 193 Topics: Cytochrome b Group; Electrons; Iron; Kinetics; Light; Models, Chemical; Mutation; Oxidation-Reduction; Protoporphyrins; Zinc	2019
Utility of fluorescent heme analogue ZnPPIX to monitor conformational heterogeneity in vertebrate hexa-coordinated globins. Metallomics : integrated biometal science, 2019, 05-22, Volume: 11, Issue:5 Topics: Animals; Circular Dichroism; Cytochromes c; Globins; Heme; Horses; Humans; Protein Conformation; Protoporphyrins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Vertebrates	2019
Production of zinc protoporphyrin IX by metabolically engineered Escherichia coli. Biotechnology and bioengineering, 2022, Volume: 119, Issue:11 Topics: Carbon; Escherichia coli; Fermentation; Heme; Iron; Metabolic Engineering; Protoporphyrins; Zinc	2022
Dissociation of ferriheme from oxidized heme proteins and re-reduction of ferriheme to ferroheme are crucial for the formation of zinc protoporphyrin IX in nitrite/nitrate-free dry-cured meat products. Food chemistry, 2023, Nov-30, Volume: 427 Topics: Azides; Heme; Hemeproteins; Hemin; Meat Products; Nitrates; Nitrites; Protoporphyrins	2023