heme has been researched along with threonine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 7 (21.88) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Imai, Y; Nakamura, M | 1 |
| Margoliash, E; Putterman, GJ; Sherman, F | 1 |
| Gupta, RK; Koenig, SH | 1 |
| Fisher, JM; Freedman, ML; Maxwell, CR; Rabinovitz, M | 1 |
| Altschuler, T; Lascelles, J | 1 |
| Honig, GR; Mason, RG; Rowan, BQ | 1 |
| Cameron, AD; Habash, J; Helliwell, JR; Li, T; Olson, JS; Smerdon, SJ; Wilkinson, AJ | 1 |
| Brinigar, WS; Bucci, E; Fronticelli, C; Gryczynski, Z; Kowalczyk, J; O'Donnell, JK; Olson, JS | 1 |
| Brinigar, WS; Fidelis, K; Fronticelli, C; Gilliland, GL; Ji, X; Karavitis, M; Moult, J; Pechik, I | 1 |
| Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Brinigar, WS; Cupane, A; Fronticelli, C; Karavitis, M; Leone, M; Militello, V; Vasquez, GB | 1 |
| Lukat-Rodgers, GS; Rodgers, KR; Rusnak, F; Wengenack, NL | 2 |
| Lee, D; Park, S; Shimizu, H; Shiro, Y; Shoun, H | 1 |
| Cvrk, T; Strobel, HW | 1 |
| Harris, DL; Loew, GH | 1 |
| Chen, JJ; Han, AP; Rafie-Kolpin, M | 1 |
| GREENGARD, O | 1 |
| Banerjee, R; Zou, CG | 1 |
| Hu, Z; Lelli, KM; Maines, MD; Miralem, T; Torno, MD | 1 |
| Blobaum, AL; Harris, DL; Hollenberg, PF | 1 |
| Bryson, TA; Davydov, R; Dawson, JH; Hoffman, BM; Jin, S; Kim, SH; Perera, R; Sono, M; Yang, TC | 1 |
| Brash, AR; Kitagawa, T; Tosha, T; Uchida, T | 1 |
| Gurel, E; Mandaci, S; Ozturk, M; Watmough, NJ | 1 |
| Cryle, MJ; De Voss, JJ | 1 |
| Hollenberg, PF; Jushchyshyn, M; Lin, HL; Zhang, H | 1 |
| Banerjee, R; Xie, P; Yadav, PK | 1 |
| Franzen, S; Jiang, S; Swartz, P; Wright, I | 1 |
| Boeglin, WE; Brash, AR; Mashhadi, Z | 1 |
| Baba, S; Barnard-Britson, S; Cai, W; Ducho, C; Funabashi, M; Garneau-Tsodikova, S; Goswami, A; Green, KD; Liu, X; Morris, AJ; Nonaka, K; Spork, AP; Sunkara, M; Thorson, JS; Van Lanen, SG; Yang, Z | 1 |
| Dojun, N; Ishimori, K; Sekine, Y; Uchida, T | 1 |
| Bell, SG; Bruning, JB; Doherty, DZ; Donald, WA; Harbort, JS; Harmer, JR; Lee, JHZ; Nguyen, GTH; Podgorski, MN | 1 |
1 review(s) available for heme and threonine
| Article | Year |
|---|---|
Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.
Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cystathionine beta-Synthase; DNA Mutational Analysis; Enzyme Activation; Heme; Hemeproteins; Humans; Kinetics; Models, Chemical; Models, Molecular; Models, Structural; Molecular Sequence Data; Molecular Structure; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity; Threonine | 2005 |
31 other study(ies) available for heme and threonine
| Article | Year |
|---|---|
Nitrogenous ligation at the sixth coordination position of the Thr-301 to Lys-mutated P450IIC2 heme iron.
Topics: Base Sequence; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; DNA Probes; Heme; Iron; Ligands; Lysine; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen; Oxidation-Reduction; Saccharomyces cerevisiae; Spectrophotometry; Threonine | 1991 |
Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Chymotrypsin; Cytochrome c Group; Electrophoresis; Genes; Heme; Hydrolysis; Isoleucine; Mutation; Peptides; Proline; RNA, Messenger; Saccharomyces cerevisiae; Serine; Threonine; Ultraviolet Rays | 1974 |
Some aspects of pH and temperature dependence of the NMR spectra of cytochrome C.
Topics: Animals; Chemical Phenomena; Chemistry; Cytochromes; Electron Transport; Heme; Horses; Hydrogen-Ion Concentration; Iron; Lysine; Magnetic Resonance Spectroscopy; Methionine; Oxidation-Reduction; Protons; Temperature; Threonine; Water | 1971 |
Translational control in hemoglobin syntheskis.
Topics: Animals; Blood Proteins; Cell-Free System; Depression, Chemical; Deuterium; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Iron Isotopes; Isoleucine; Leucine; Liver; Metabolism; Models, Biological; Models, Structural; Peptide Biosynthesis; Porphyrins; Pyridines; Rabbits; Reticulocytes; Ribosomes; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Spectrophotometry; Stimulation, Chemical; Temperature; Threonine; Ultraviolet Rays | 1969 |
Mutant strains of Rhodopseudomonas spheroides lacking delta-aminolevulinate synthase: growth, heme, and bacteriochlorophyll synthesis.
Topics: Acyltransferases; Amino Acids; Azaguanine; Carbon Isotopes; Chlorophyll; Heme; Iron Isotopes; Levulinic Acids; Mutation; Puromycin; Pyrroles; Rhodopseudomonas; Threonine | 1969 |
Unequal synthesis of complementary globin chains of human fetal hemoglobin by the effect of L-O-methylthreonine.
Topics: Blood Proteins; Carbon Isotopes; Chromatography, Gel; Complement System Proteins; Depression, Chemical; Erythroblastosis, Fetal; Female; Fetal Hemoglobin; Globins; Heme; Hemolysis; Humans; In Vitro Techniques; Infant, Newborn; Isoleucine; Leucine; Lysine; Peptide Biosynthesis; Pregnancy; Solubility; Thalassemia; Threonine | 1969 |
Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Topics: Animals; Crystallography, X-Ray; Heme; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry, Infrared; Structure-Activity Relationship; Swine; Threonine | 1993 |
Recombinant human hemoglobin: modification of the polarity of the beta-heme pocket by a valine67(E11)-->threonine mutation.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Escherichia coli; Heme; Hemoglobins; Humans; Kinetics; Ligands; Macromolecular Substances; Mathematics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides, Antisense; Recombinant Proteins; Threonine; Valine | 1993 |
Crystallographic, molecular modeling, and biophysical characterization of the valine beta 67 (E11)-->threonine variant of hemoglobin.
Topics: Biophysical Phenomena; Biophysics; Carboxyhemoglobin; Crystallography, X-Ray; Electrochemistry; Genetic Variation; Heme; Hemoglobin A; Hemoglobins; Humans; In Vitro Techniques; Models, Molecular; Nitric Oxide; Oxidation-Reduction; Point Mutation; Protein Conformation; Protein Folding; Protein Processing, Post-Translational; Recombinant Proteins; Threonine | 1996 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine | 1997 |
Properties of human hemoglobins with increased polarity in the alpha- or beta-heme pocket. Carbonmonoxy derivatives.
Topics: Carboxyhemoglobin; Globins; Heme; Hemoglobin A; Humans; Macromolecular Substances; Models, Molecular; Point Mutation; Protein Conformation; Spectrophotometry; Temperature; Thermodynamics; Threonine; Valine | 1998 |
Spectroscopic comparison of the heme active sites in WT KatG and its S315T mutant.
Topics: Bacterial Proteins; Binding Sites; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Histidine; Ligands; Mutation; Mycobacterium tuberculosis; Peroxidases; Recombinant Proteins; Serine; Spectrum Analysis, Raman; Threonine | 2000 |
Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s.
Topics: Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Electrons; Fusarium; Heme; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Mutation; Nitric Oxide; Oxidoreductases; Protein Conformation; Protein Structure, Secondary; Protons; Recombinant Proteins; Serine; Spectrophotometry; Temperature; Threonine; Valine; Water | 2000 |
Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1.
Topics: Amino Acid Substitution; Animals; Benzene Derivatives; Binding Sites; Binding, Competitive; Catalysis; Circular Dichroism; Cytochrome P-450 CYP1A1; Electrophoresis, Polyacrylamide Gel; Heme; Hydroxylation; Mutagenesis, Site-Directed; Propanols; Rats; Structure-Activity Relationship; Substrate Specificity; Testosterone; Threonine | 2001 |
Carbon monoxide adducts of KatG and KatG(S315T) as probes of the heme site and isoniazid binding.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Isoniazid; Mycobacterium tuberculosis; Peroxidases; Serine; Spectrum Analysis, Raman; Threonine | 2001 |
A role for Thr 252 in cytochrome P450cam oxygen activation.
Topics: Binding Sites; Camphor; Camphor 5-Monooxygenase; Computer Simulation; Ferric Compounds; Ferrous Compounds; Heme; Hydrogen; Hydrogen Peroxide; Hydroxylation; Models, Molecular; Oxygen; Pseudomonas putida; Reactive Oxygen Species; Threonine | 1994 |
Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Blotting, Western; Cell Line; Chromatography, Thin Layer; Dose-Response Relationship, Drug; eIF-2 Kinase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Eukaryotic Initiation Factor-2; Heme; Hemin; Humans; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Protein Structure, Tertiary; Threonine; Trypsin | 2003 |
THE ROLE OF COENZYMES, CORTISONE AND RNA IN THE CONTROL OF LIVER ENZYME LEVELS.
Topics: Adrenalectomy; Coenzymes; Cortisone; Dactinomycin; Heme; Hydro-Lyases; Liver; Metabolism; Peroxidases; Pharmacology; Puromycin; Rats; Research; RNA; Threonine; Transaminases; Tryptophan | 1963 |
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells.
Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; Arsenites; Biliverdine; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Silencing; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Luciferases; Membrane Glycoproteins; Membrane Proteins; Oligonucleotides; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Phosphorylation; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Retroviridae; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Compounds; Threonine; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha | 2005 |
P450 active site architecture and reversibility: inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenes.
Topics: Alanine; Alkynes; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P450 Family 2; Enzyme Inhibitors; Ethers; Heme; Hydrogen Bonding; Models, Molecular; Oxidants; Peroxides; Rabbits; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Threonine | 2005 |
Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant.
Topics: Alanine; Camphor 5-Monooxygenase; Carbon Isotopes; Catalysis; Electron Spin Resonance Spectroscopy; Fluorine; Heme; Iron; Kinetics; Models, Molecular; Mutant Proteins; Mutation; Oxidation-Reduction; Oxygen; Protein Binding; Protein Structure, Tertiary; Solvents; Substrate Specificity; Threonine | 2005 |
On the relationship of coral allene oxide synthase to catalase. A single active site mutation that induces catalase activity in coral allene oxide synthase.
Topics: Animals; Anthozoa; Binding Sites; Catalase; Heme; Histidine; Hydrogen Bonding; Hydrogen Peroxide; Intramolecular Oxidoreductases; Models, Chemical; Models, Molecular; Mutation; Spectrum Analysis, Raman; Threonine | 2006 |
Site-directed mutagenesis of five conserved residues of subunit i of the cytochrome cbb3 oxidase in Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Bacterial Proteins; Catalysis; Cytochromes c; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Heme; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Subunits; Rhodobacter capsulatus; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Threonine | 2007 |
The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.
Topics: Alanine; Amino Acid Sequence; Bacillus megaterium; Binding Sites; Catalysis; Cytochrome P-450 Enzyme System; Fatty Acids; Heme; Hydroxylation; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oxidation-Reduction; Oxygen; Substrate Specificity; Threonine | 2008 |
Covalent modification of Thr302 in cytochrome P450 2B1 by the mechanism-based inactivator 4-tert-butylphenylacetylene.
Topics: Acetylene; Amino Acid Sequence; Capillary Electrochromatography; Catalytic Domain; Cytochrome P-450 CYP2B1; Databases, Protein; Escherichia coli; Heme; Hydrolysis; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrum Analysis; Threonine; Trypsin | 2010 |
Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase.
Topics: Allosteric Regulation; Binding Sites; Cystathionine beta-Synthase; Heme; Homocystinuria; Humans; Hydrogen Peroxide; Iron; Isomerism; Kinetics; Mutation; Oxidation-Reduction; Protein Carbonylation; Pyridoxal Phosphate; S-Adenosylmethionine; Spectrometry, Fluorescence; Threonine | 2012 |
The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata.
Topics: Animals; Biocatalysis; Heme; Hemoglobins; Histidine; Iron; Kinetics; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Peroxidases; Polychaeta; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Threonine | 2013 |
Inhibitory effects of a novel Val to Thr mutation on the distal heme of human catalase.
Topics: Amino Acid Sequence; Biocatalysis; Catalase; Catalytic Domain; Crystallography, X-Ray; Heme; Humans; Hydrogen Bonding; Hydrogen Peroxide; Models, Molecular; Molecular Structure; Mutant Proteins; Mutation, Missense; Peroxides; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Threonine; Valine | 2014 |
The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.
Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Drug Design; Drug Resistance, Bacterial; Escherichia coli; Heme; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Multigene Family; Open Reading Frames; Phosphorylation; Polymerase Chain Reaction; Protein Binding; Recombinant Proteins; Streptomyces; Threonine; Transaldolase; Uridine; Uridine Monophosphate | 2015 |
Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae.
Topics: Bacterial Proteins; Ferric Compounds; Heme; Hydrogen; Iron; Iron Chelating Agents; Kinetics; Threonine; Vibrio cholerae; Water | 2017 |
Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant.
Topics: Cytochrome P-450 Enzyme System; Glutamates; Heme; Iron; Ligands; Nitrogen; Threonine | 2023 |