heme has been researched along with spironolactone in 4 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gillette, JR; Guenthner, TM; Kon, H; Menard, RH | 1 |
Correia, MA; Decker, C; Sugiyama, K; Underwood, M | 1 |
Gillette, JR; Menard, RH; Stripp, B | 1 |
Correia, MA; He, K; Licad-Coles, E; Yin, H | 1 |
4 other study(ies) available for heme and spironolactone
Article | Year |
---|---|
Studies on the destruction of adrenal and testicular cytochrome P-450 by spironolactone. Requirement for the 7alpha-thio group and evidence for the loss of the heme and apoproteins of cytochrome P-450.
Topics: Adrenal Glands; Animals; Apoenzymes; Cytochrome P-450 Enzyme System; Dogs; Guinea Pigs; Heme; Male; Microsomes; Rats; Species Specificity; Spironolactone; Structure-Activity Relationship; Testis | 1979 |
Inactivation of rat hepatic cytochrome P-450 by spironolactone.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Dexamethasone; Drug Synergism; Heme; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Spironolactone; Time Factors; Troleandomycin | 1986 |
Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism.
Topics: Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Cytochromes; Dogs; Female; Guinea Pigs; Heme; Liver; Male; Methyltestosterone; Mice; Microsomes; Pregnenolone; Progesterone; Rabbits; Rats; Spironolactone; Steroid Hydroxylases; Testis; Testosterone | 1974 |
Cytochrome P450 2C11: Escherichia coli expression, purification, functional characterization, and mechanism-based inactivation of the enzyme.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dicarbethoxydihydrocollidine; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Gene Expression; Heme; In Vitro Techniques; Male; Molecular Sequence Data; Rats; Recombinant Proteins; Sex Characteristics; Spironolactone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1997 |