heme has been researched along with porphobilinogen in 114 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 75 (65.79) | 18.7374 |
1990's | 6 (5.26) | 18.2507 |
2000's | 11 (9.65) | 29.6817 |
2010's | 15 (13.16) | 24.3611 |
2020's | 7 (6.14) | 2.80 |
Authors | Studies |
---|---|
Abboud, MM; Akhtar, M; Barnard, G; Jordan, P; Zaman, Z | 1 |
Bennett, M; Frykholm, BC; Lamon, JM; Tschudy, DP | 1 |
Brodie, MJ; Goldberg, A; Graham, DJ; McColl, KE; Moore, MR | 1 |
Bossenmaier, I; Cardinal, R; Pierach, CA; Watson, CJ | 2 |
Gidari, AS; Levere, RD | 1 |
Becker, DM; Kramer, S | 1 |
Walsh, JR | 1 |
Doss, M | 1 |
Albritton, WL; Hammond, GW; Lian, CJ; Ronald, AR; Wilt, JC | 1 |
Druschky, KF; Schaller, KH; Schwanitz, G | 1 |
Charles, HP; McConville, ML | 1 |
Armas Merino, R; Canals, C; Gómez, R; Monsalve, V; Wolff, C | 1 |
Brodie, MJ; Goldberg, A; Hardie, RA; Hunter, JA; McColl, KE; Moore, MR; Thompson, GG | 1 |
Bacheschi, LA; de Assis, JL; Do Serro-Azul, LG; Marchiori, PE; Moraes, EC; Scaff, M; Yassuda, N | 1 |
Lithner, F | 1 |
Goldberg, A; Ippen, H; Moore, MR; Seubert, A; Seubert, S; Thompson, GG | 1 |
Neethling, AC; Percy, VA; Shanley, BC | 1 |
Bossenmaier, I; Cardinal, R; Peterson, A; Watson, CJ | 1 |
Ross, J; Sautner, D | 1 |
Bossenmaier, I; Cardinal, R; Dhar, GJ; Petryka, ZJ; Watson, CJ | 2 |
Watson, CJ | 1 |
Frederickson, EL; Mees, DE | 1 |
Morrone, G | 1 |
Cheek, EM; Cole, RJ; Garlick, J | 1 |
Eryürek, FG; Sürmen, E | 1 |
el-Sharabasy, MM; el-Waseef, AM; Hafez, MM; Salim, SA | 1 |
Goldberg, A; Herrick, AL; McColl, KE; Moore, MR; Wallace, AM | 1 |
Aldonatti, C; San Martín de Viale, LC; Vila, MC | 1 |
Rimington, C | 1 |
Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Thompson, GG | 1 |
Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Park, BK; Thompson, GG | 1 |
Goldberg, A; Moore, MR; Yeung Laiwah, AC | 1 |
Bissell, DM | 1 |
Bonkovsky, HL; Healey, JF; Robinson, JM; Shedlofsky, SI; Sinclair, PR; Swim, AT | 1 |
Arrol, S; Cutler, MG | 1 |
Ch'ng, SL; Jeyamalar, R | 1 |
Fuchs, T; Ippen, H | 1 |
Lindén, IB; Tenhunen, R; Tokola, O | 1 |
Datta, K; Shanker, J | 1 |
Guthrie, R; Ho, J; Tieckelmann, H | 1 |
Bernstein, M; Shivji, A | 1 |
Doss, M; Sixel-Dietrich, F; Verspohl, F | 1 |
Berek, I; Ivánovics, G; Miczák, A | 1 |
Nair, PP; Solomon, D; Strummer, D | 1 |
Meyer, UA; Schmid, R | 2 |
Levin, EY | 1 |
Hatch, T; Lascelles, J | 1 |
Crispin, M; Szeinberg, A | 1 |
Berk, PD; Berlin, NI; Bloomer, JR; Howe, RB; Jones, EA; Shrager, R | 1 |
Embry, TL; Morgan, DP; Roan, CC | 1 |
Amrutavalli, J; Padmanaban, G; Rajamanickam, C; Rao, MR | 1 |
Winterhalter, KH | 1 |
Stich, W | 1 |
Dech, G; Fikentscher, R; Schmidt, D; Stich, W | 1 |
Manning, J; Marver, HS; Strand, LJ | 1 |
Burger, P; Dowdle, EB; Wilson, E | 1 |
Doss, M; Kaltepoth, B | 1 |
Friedland, ML; Ibraham, NG; Levere, RD | 1 |
Atsmon, A; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N | 1 |
Bonkowsky, HL; Schady, W | 1 |
Chang, KJ; Lee, TP; Lu, FJ; Tung, TC | 1 |
Goldberg, A; Laiwah, AC; Moore, MR | 1 |
Romeo, G | 1 |
Bock, W; Bringmann, G; Fels, G; Franck, B; Grubenbecher, F; Marsmann, M; Pietschmann, R; Schäpers, K; Spiegel, U; Steinkamp, R; Ufer, G; Wegner, C | 1 |
Kappas, A; Sassa, S | 1 |
Waldenström, J | 1 |
Goldberg, A; McColl, KE; Moore, MR; Thompson, GG; Wallace, AM | 1 |
Tiller, FW | 1 |
Hashimoto, Y; Kondo, M; Shionoya, S; Urabe, A; Urata, G | 1 |
Adam, C; Defresne, C; Guilmot-Bruneau, M; Hassoun, A; Saussez-De Temmerman, A; Wery-Follet, B | 1 |
Bonkowsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR | 1 |
Bloomer, JR; Brenner, DA | 1 |
Urata, G | 1 |
Buzaleh, AM; del Carmen Batlle, AM; Nuñez, G; Vazquez, ES | 1 |
Hift, RJ | 1 |
de Rooij, FW; Edixhoven, A; Hinnen, P; Siersema, PD; Terlouw, EM; Tilanus, HW; van Dekken, H; van Hillegersberg, R; Wilson, JH | 1 |
Doss, MO; Gross, U; Kühnel, A | 1 |
Elder, GH; Hift, RJ | 1 |
Araujo, LS; Batlle, A; Lombardo, ME | 1 |
DRESEL, EI; FALK, JE | 1 |
DANCEWICZ, AM | 1 |
FELDMAN, F; LICHTMAN, HC | 1 |
Beaumont, N; Deacon, A; Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ; Solanky, N; Srai, SK | 1 |
Herrick, AL; McColl, KE | 1 |
Ambekar, JG; Bhagwat, VR; Das, KK; Dongre, NN; Patil, AJ; Patil, JA | 1 |
Feder, ZM; Ignashina, EV; Karpova, IV; Kravchenko, SK; Kremenetskaia, AM; Kurtser, MA; Mironova, TS; Murashko, LE; Petrova, VI; Pustovoĭt, IaS; Pustovoĭt, LA; Shmakov, RG; Shtabnitskiĭ, AM; Sokolova, MIu | 1 |
Bloomer, JR; McGuire, BM | 1 |
Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ | 1 |
Andersson, DE; Floderus, Y; Harper, P; Sardh, E | 1 |
Choiniere, JR; Gelb, MH; Scott, CR; Turecek, F | 1 |
Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D | 1 |
Ma, E; Mar, V; Nicoll, A; Ross, G; Varigos, G | 1 |
Czarnecki, O; Grimm, B; Peter, E | 1 |
Badminton, MN; Barth, JH; Cox, TM; Rees, DC; Sarkany, R; Stein, PE; Stewart, MF | 1 |
González-Bayón, R; Hricová, A; Micol, JL; Ponce, MR; Quesada, V; Sarmiento-Mañús, R | 1 |
Bonkovsky, HL; Caballes, FR; Finkielstein, CV; Groseclose, G; Hwang, SI; Larion, S; Lee, JG; Li, T; Maddukuri, V; Parsons, J; Rossman, WE; Steuerwald, N | 1 |
Anderson, KE; Arvelakis, A; Balwani, M; Chen, B; Clavero, S; Desnick, RJ; Erwin, AL; Fiel, MI; Florman, SS; Gan, L; Gordon, RE; Kadirvel, S; Liu, LU; Martin, LD; Naik, H; Phillips, JD; Sadagoparamanujam, VM; Yasuda, M; Yu, C | 1 |
Dosi, R; Joshi, H; Patell, R; Shah, P; Tripathi, R | 1 |
Balwani, M; Chen, B; Debnath, EM; Desnick, RJ; Doheny, D; Naik, H; Seth, A; Singh, P; Yasuda, M | 1 |
Anderson, KE; Bissell, DM; Bonkovsky, HL | 1 |
Barman-Aksözen, J; Huber, LC; Minder, E; Senn, JD | 1 |
Batlle, AMDC; Buzaleh, AM; Gerez, EN; Lavandera, JV; Martínez, MDC; Oliveri, LM; Ruspini, SF; Zuccoli, JR | 1 |
Bonkovsky, HL; Dixon, N; Rudnick, S | 1 |
Anderson, KE | 1 |
Comentale, G; Manzo, R; Pilato, E | 1 |
Anderson, KE; Chan, A; Desnick, RJ; Lahiji, AP; Ramanujam, VMS; Simon, A | 1 |
Erlandsen, EJ; Randers, E; Thomsen, HH; Østergaard, MGØ | 1 |
Amaddeo, G; Bayard, Q; Blanc, JF; Calderaro, J; Letouzé, E; Ma, X; Molina, L; Trépo, E; Zhu, J; Zucman-Rossi, J | 1 |
Córdoba, KM; Ena, J; Enríquez de Salamanca, R; Fontanellas, A; Jericó, D; Morales-Conejo, M; Solares, I | 1 |
Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B | 1 |
Anderson, KE; Dickey, A; Erwin, A; Leaf, RK; Moghe, A; O'Brien, A; Quigley, JG; Thapar, M | 1 |
26 review(s) available for heme and porphobilinogen
Article | Year |
---|---|
Enzymatic formation and cellular regulation of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coenzyme A; Coproporphyrinogens; Enzyme Induction; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrins; Uroporphyrinogens | 1977 |
The neurological manifestations of porphyria: a review.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Liver; Liver Diseases; Nervous System; Neurologic Manifestations; Peripheral Nerves; Porphobilinogen; Porphyrias; Porphyrins | 1977 |
Hepatic porphyrias. Current concepts.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Coproporphyrinogens; Female; Genetic Diseases, Inborn; Heme; Humans; Liver Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Uroporphyrinogens | 1977 |
[Pathobiochemistry of porphyrias].
Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme; Humans; Liver; Liver Diseases; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins | 1977 |
Use of hematin in the acute attack of the "inducible" hepatic prophyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Female; Heme; Hemin; Humans; Male; Middle Aged; Neurologic Manifestations; Porphobilinogen; Porphyrias; Prognosis | 1978 |
[Chromosome studies in patients with intermittent porphyria].
Topics: Adult; Aminolevulinic Acid; Chromosome Aberrations; Female; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias | 1979 |
Haem biosynthesis and porphyrias: 50 years in retrospect.
Topics: Biochemistry; Heme; History, 20th Century; Humans; Models, Biological; Porphobilinogen; Porphyrias; Porphyrins; Retrospective Studies | 1989 |
Pathogenesis of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Nervous System; Porphobilinogen; Porphyrias | 1987 |
Intermittent acute porphyria: the enzymatic defect.
Topics: 5-Aminolevulinate Synthetase; Adenosine Triphosphatases; Alanine; Aminolevulinic Acid; Ammonia-Lyases; Dysautonomia, Familial; Heme; Humans; Liver; Porphobilinogen; Porphyrias; Porphyrins | 1974 |
[Hepatic porphyrias].
Topics: Animals; Heme; Humans; Levulinic Acids; Liver; Porphobilinogen; Porphyrias; Porphyrins | 1972 |
Heme metabolism in erythroid and hepatic cells.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrinogen Oxidase; Erythrocytes; Erythropoiesis; Ferrochelatase; Flavoproteins; Heme; Heme Oxygenase (Decyclizing); Humans; Liver; Liver Diseases; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase; Uroporphyrinogen III Synthetase | 1983 |
Neurologic manifestations of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Heme; Humans; Light; Liver Diseases; Muscle Hypotonia; Nerve Fibers; Nerve Fibers, Myelinated; Nervous System Diseases; Pain, Intractable; Peripheral Nerves; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Prognosis; Seizures; Vitamin B 6 Deficiency; Zinc | 1982 |
The hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Gene Expression Regulation; Heme; Humans; Infant; Liver; Liver Diseases; Male; Middle Aged; Photosensitivity Disorders; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Porphyrins; Prenatal Diagnosis; Protoporphyria, Erythropoietic; Recurrence; Skin Diseases | 1980 |
Genetic, metabolic, and biochemical aspects of the porphyrias.
Topics: Aminolevulinic Acid; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Erythrocytes; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrinogens; Porphyrins; Rodent Diseases; Sciuridae; Swine; Swine Diseases | 1981 |
The porphyrias--a review.
Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Diseases; Male; Porphobilinogen; Porphyrias; Skin Diseases; Time Factors | 1981 |
[The chemistry of porphyrins and their precursors on the heme biosynthetic chain].
Topics: Aminolevulinic Acid; Heme; Humans; Porphobilinogen; Porphyrins; Uroporphyrinogens | 1995 |
Treatment of acute porphyria.
Topics: Adolescent; Adult; Analgesics, Opioid; Arginine; Clinical Trials as Topic; Dietary Carbohydrates; Female; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Pregnancy; Pregnancy Complications; Treatment Outcome | 2001 |
Acute intermittent porphyria.
Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Humans; Porphobilinogen; Porphyria, Acute Intermittent | 2005 |
Porphyrias at a glance: diagnosis and treatment.
Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrins | 2010 |
Acute Intermittent Porphyria in children: A case report and review of the literature.
Topics: Child; Female; Genetic Testing; Heme; Humans; Hydroxymethylbilane Synthase; Male; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; RNA Splice Sites; Seizures | 2016 |
Porphyria.
Topics: Female; Heme; Hemin; Humans; Male; Phlebotomy; Porphobilinogen; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyrins; Prognosis; Protoporphyria, Erythropoietic; RNA, Small Interfering; Sunlight; Symptom Assessment | 2017 |
[CME: Acute Intermittent Porphyria: When to Think of It? What Must be Checked? How to Treat?]
Topics: Arginine; Combined Modality Therapy; Diagnosis, Differential; Female; Genetic Predisposition to Disease; Heme; Hemin; Humans; Interdisciplinary Communication; Intersectoral Collaboration; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Prognosis; Recurrence; Risk Factors | 2018 |
Pathogenesis and clinical features of the acute hepatic porphyrias (AHPs).
Topics: Anxiety; Heme; Humans; Mutation; Neuralgia; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic; Sleep Initiation and Maintenance Disorders | 2019 |
Acute hepatic porphyrias: Current diagnosis & management.
Topics: Animals; Biosynthetic Pathways; Clinical Trials as Topic; Disease Management; Heme; Hemin; Humans; Mice; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic | 2019 |
Understanding Carbohydrate Metabolism and Insulin Resistance in Acute Intermittent Porphyria.
Topics: Aminolevulinic Acid; Animals; Carbohydrate Metabolism; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Insulin; Insulin Resistance; Mice; Porphobilinogen; Porphyria, Acute Intermittent | 2022 |
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review.
Topics: Abdominal Pain; Aminolevulinic Acid; Antiemetics; Carcinoma, Hepatocellular; Creatinine; Female; Heme; Hemin; Humans; Hypertension; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; Quality of Life; Renal Insufficiency, Chronic; United States | 2023 |
2 trial(s) available for heme and porphobilinogen
Article | Year |
---|---|
Effects of sodium valproate on haem biosynthesis in man: implications for seizure management in the porphyric patient.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Drug Administration Schedule; Epilepsy; Female; Heme; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Valproic Acid | 1988 |
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug Monitoring; Female; Glucose; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity | 2009 |
86 other study(ies) available for heme and porphobilinogen
Article | Year |
---|---|
Mechanism and stereochemistry of enzymic reactions involved in porphyrin biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Carboxy-Lyases; Glycine; Heme; Porphobilinogen; Porphyrins; Stereoisomerism; Uroporphyrinogen Decarboxylase; Vinyl Compounds | 1976 |
Prevention of acute porphyric attacks by intravenous haematin.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Pressure; Circadian Rhythm; Drug Evaluation; Female; Heme; Hemin; Humans; Infusions, Parenteral; Menstruation; Porphobilinogen; Porphyrias; Pulse; Remission, Spontaneous | 1978 |
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinogen; Porphyrias; Pyrroles | 1979 |
Postulated deficiency of hepatic heme and repair by hematin infusions in the "inducible" hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Adult; Female; Heme; Hemin; Humans; Liver; Male; Porphobilinogen; Porphyrias | 1977 |
Determination of the hemin requirement of Haemophilus ducreyi: evaluation of the porphyrin test and media used in the satellite growth test.
Topics: Bacteriological Techniques; Culture Media; Factor X; Haemophilus ducreyi; Heme; Hemin; Porphobilinogen; Porphyrins | 1978 |
Mutants of Escherichia coli K12 accumulating porphobilinogen: a new locus, hemC.
Topics: Chromosome Mapping; Escherichia coli; Genes; Heme; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; Transduction, Genetic | 1979 |
[Effect of hematin in acute porphyric relapse].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Heme; Hemin; Humans; Male; Porphobilinogen; Porphyrias; Uroporphyrins | 1979 |
Haem biosynthesis in cutaneous hepatic porphyria: comparison with alcoholism and liver disease.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases, Alcoholic; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase | 1979 |
[Hematin treatment of acute intermittent porphyria. A case report (author's transl)].
Topics: Adolescent; Aminolevulinic Acid; Antihypertensive Agents; Electromyography; Female; Heme; Hemin; Humans; Infusions, Parenteral; Lung; Porphobilinogen; Porphyrias | 1979 |
[Acute intermittent porphyria--a clinical review].
Topics: Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Heme; Humans; Porphobilinogen; Porphyrias | 1979 |
The biosynthesis of haem in congenital (erythropoietic) porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Child; Child, Preschool; Coproporphyrinogens; Erythrocytes; Erythropoiesis; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrinogens | 1978 |
Pathogenesis of neural manifestations in acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Anura; Brain; Heme; Humans; In Vitro Techniques; Mice; Neurologic Manifestations; Porphobilinogen; Porphyrias; Rats | 1977 |
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Heme; Hemin; Humans; Infusions, Parenteral; Porphobilinogen; Porphyrias; Remission, Spontaneous | 1976 |
Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells.
Topics: Aminolevulinic Acid; Biliverdine; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Erythropoiesis; Globins; Heme; Hemin; Hemoglobins; Kinetics; Porphobilinogen; RNA, Messenger; RNA, Neoplasm | 1976 |
Effects of hematin in hepatic porphyria. Further studies.
Topics: Adult; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Recurrence | 1975 |
Editorial: Hematin and porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Animals; Female; Heme; Hemin; Humans; Kidney Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Rabbits; Rats | 1975 |
Anesthesia and the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Anesthesia; Anesthetics; Child; Chlordiazepoxide; Cytochrome P-450 Enzyme System; Demyelinating Diseases; Diazepam; Heme; Humans; Neostigmine; Pentazocine; Porphobilinogen; Porphyrias; Thiopental | 1975 |
[The etiopathogenesis and clinical classification of congenital and acquired porphyrias].
Topics: Animals; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrinogens; Porphyrins | 1975 |
Activities of haem synthetic enzymes in blood cells of pre-natal flexed-tailed (f/f) anaemic mice.
Topics: 5-Aminolevulinate Synthetase; Anemia; Animals; Erythrocytes; Fetal Blood; Heme; Iron; Liver; Lyases; Mice; Mice, Inbred Strains; Mutation; Porphobilinogen; Porphobilinogen Synthase; Porphyrinogens; Porphyrins; Reticulocytes | 1975 |
Liver delta-aminolevulinate dehydratase activity in amitriptyline- or chlorpromazine-treated rats.
Topics: Amitriptyline; Animals; Chlorpromazine; Heme; Liver; Male; Porphobilinogen; Porphobilinogen Synthase; Rats; Rats, Wistar | 1992 |
Porphyrin metabolism in some malignant diseases.
Topics: Adult; Aminolevulinic Acid; Child; Coproporphyrins; Erythrocytes; Female; Ferrochelatase; Heme; Hodgkin Disease; Humans; Hydroxymethylbilane Synthase; Lymphoma, Non-Hodgkin; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uroporphyrins | 1992 |
Elevation of hormone-binding globulins in acute intermittent porphyria.
Topics: Adolescent; Adult; Aminolevulinic Acid; Arginine; Carrier Proteins; Heme; Humans; Hydrocortisone; Liver Diseases; Porphobilinogen; Porphyrias; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Thyroxine-Binding Proteins | 1990 |
[Evaluation of porphyrinogenic effect of lindane in rats].
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Heme; Hexachlorocyclohexane; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
The effects of chronic carbamazepine treatment of haem biosynthesis in man and rat.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Animals; Carbamazepine; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats; Rats, Inbred Strains | 1988 |
Treatment of acute hepatic porphyria with hematin.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Liver Diseases; Male; Middle Aged; Porphobilinogen; Porphyrias | 1988 |
Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Heme; Levulinic Acids; Liver; Methylcholanthrene; Porphobilinogen; Porphyrins | 1987 |
Pharmacological effects of haem biosynthetic intermediates in isolated intestinal preparations.
Topics: Aminolevulinic Acid; Animals; Colon; Coproporphyrins; Female; Glycine; Heme; Hemin; In Vitro Techniques; Intestinal Mucosa; Intestines; Jejunum; Male; Muscle Contraction; Porphobilinogen; Protoporphyrins; Rabbits; Succinates | 1987 |
Acute intermittent porphyria: the first case report in Malaysia.
Topics: Acute Disease; Adult; Female; Heme; Humans; Malaysia; Porphobilinogen; Porphyrias | 1986 |
[Treatment of acute intermittent porphyria with a new protein-bound lyophilized hematin].
Topics: Acute Disease; Adult; Female; Freeze Drying; Heme; Hemin; Humans; Porphobilinogen; Porphyrias; Protein Binding | 1987 |
The effects of haem arginate and haematin upon the allylisopropylacetamide induced experimental porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Arginine; Heme; Hemin; Liver; Male; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains | 1987 |
Affinity purification and properties of rat liver mitochondrial L-alanine:4,5-dioxovalerate transaminase and its inhibition by hemin.
Topics: Animals; Bilirubin; Chromatography, Affinity; Heme; Hemin; Kinetics; Male; Mitochondria, Liver; Molecular Weight; Porphobilinogen; Protoporphyrins; Rats; Spectrum Analysis; Transaminases | 1986 |
Detection of delta-aminolevulinic acid, porphobilinogen and porphyrins related to heme biosynthesis by high-performance liquid chromatography.
Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Levulinic Acids; o-Phthalaldehyde; Porphobilinogen; Porphyrins | 1986 |
Stimulation of 5-aminolevulinic acid metabolism by uroporphyrinogen I in rat liver homogenate.
Topics: Aminolevulinic Acid; Animals; Cell-Free System; Heme; In Vitro Techniques; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrinogens; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrinogens | 1985 |
"Glucose effect" and rate limiting function of uroporphyrinogen synthase on porphyrin metabolism in hepatocyte culture: relationship with human acute hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Cells, Cultured; Chick Embryo; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Kinetics; Liver; Liver Diseases; Meprobamate; Porphobilinogen; Porphyrias; Porphyrins | 1985 |
Mapping the delta-aminolaevulinic acid dehydrase and porphobilinogen deaminase loci in Bacillus subtilis.
Topics: Ammonia-Lyases; Bacillus subtilis; Bacteriophages; Chromosome Mapping; Crosses, Genetic; Crossing Over, Genetic; Deamination; Genotype; Heme; Hydro-Lyases; Porphobilinogen; Porphobilinogen Synthase; Recombination, Genetic; Transduction, Genetic | 1974 |
Relationship between vitamin E and urinary excretion of ketosteroid fractions in cystic mastitis.
Topics: 17-Ketosteroids; Adult; Androsterone; Chronic Disease; Cysts; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Female; Heme; Hemeproteins; Humans; Levulinic Acids; Mastitis; Menstruation; Middle Aged; Ovulation; Porphobilinogen; Porphyrins; Pregnancy; Pregnanes; Pregnanetriol; Vitamin E | 1972 |
Comparative aspects of porphyria in man and animals.
Topics: Adult; Aminolevulinic Acid; Animals; Cattle; Drug Stability; Female; Genes, Recessive; Heme; Heterozygote; Hot Temperature; Humans; Isomerases; Kinetics; Male; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Reticulocytes; Sciuridae | 1974 |
Accumulation of porphobilinogen and other pyrroles by mutant and wild type Rhodopseudomonas spheroides: regulation by heme.
Topics: 5-Aminolevulinate Synthetase; Carboxy-Lyases; Chlorophyll; Feedback; Genetics, Microbial; Heme; Hydro-Lyases; Iron; Iron Isotopes; Levulinic Acids; Mutation; Phenanthrolines; Porphobilinogen; Porphyrins; Propionates; Puromycin; Pyrroles; Rhodobacter sphaeroides; Rhodopseudomonas | 1972 |
Quantitative studies of the delivery of hepatic-synthesized bilirubin to plasma utilizing -aminolevulinic acid-4- 14 C and bilirubin- 3 H in man.
Topics: Adult; Bile Pigments; Bilirubin; Carbon Isotopes; Chromium Isotopes; Feces; Hematocrit; Heme; Humans; Injections, Intravenous; Levulinic Acids; Liver; Mathematics; Methods; Porphobilinogen; Porphyrias; Porphyrins; Time Factors; Tritium | 1972 |
Search for abnormalities of heme synthesis and sympathoadrenal activity--in workers regularly exposed to pesticides.
Topics: Adrenal Glands; Arizona; Catecholamines; Cholinesterases; Chromatography, Gas; DDT; Dieldrin; Environmental Exposure; Heme; Humans; Insecticides; Levulinic Acids; Nitrophenols; Occupational Diseases; Parathion; Pesticide Residues; Pesticides; Porphobilinogen; Porphyrins; Sympathetic Nervous System; Toxaphene | 1972 |
Effect of hexachlorobenzene on haem synthesis.
Topics: 5-Aminolevulinate Synthetase; Amino Acids; Animals; Benzene Derivatives; Cells, Cultured; Chlorine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life; Heme; Hydro-Lyases; In Vitro Techniques; Insecticides; Liver; Microsomes, Liver; Organ Size; Plants; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1972 |
Structure and synthesis of heme and references to globin synthesis.
Topics: 5-Aminolevulinate Synthetase; Globins; Heme; Iron; Levulinic Acids; Metabolism, Inborn Errors; Peptide Chain Initiation, Translational; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins; Protein Conformation | 1972 |
[Clinically important disorders of heme synthesis].
Topics: 5-Aminolevulinate Synthetase; Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Erythrocytes; Heme; Humans; Iron; Porphobilinogen; Porphyrias; Porphyrins | 1972 |
Hereditary hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Cytochrome P-450 Enzyme System; Erythrocytes; Heme; Humans; Liver; Microsomes, Liver; Porphobilinogen; Porphyrias | 1973 |
Effect of hematin in acute porphyric relapse.
Topics: 5-Aminolevulinate Synthetase; Adult; Alcohol Drinking; Heme; Humans; Injections, Intravenous; Male; Porphobilinogen; Porphyrias; Porphyrins; Substance-Related Disorders | 1973 |
[Fetal heme synthesis in various stages of blood formation].
Topics: Chromatography, Thin Layer; Erythrocytes; Fetus; Hematopoiesis; Heme; Humans; Hydro-Lyases; Levulinic Acids; Liver; Porphobilinogen; Porphyrins; Reticulocytes; Spleen | 1972 |
Acute intermittent porphyria: studies of the enzymatic basis of disordered haem biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Acyltransferases; Animals; Birds; Heme; Humans; In Vitro Techniques; Liver; Lyases; Porphobilinogen; Porphyrias; Porphyrins | 1971 |
Symptomatic porphyria I. The effects of lead on the synthesis of porphyrin and haem.
Topics: Adult; Amino Acids; Animals; Chickens; Erythrocytes; Heme; Humans; Hydro-Lyases; Lead; Lead Poisoning; Levulinic Acids; Male; Middle Aged; Porphobilinogen; Porphyrins | 1971 |
Porphyrin biosynthesis in liver cell cultures.
Topics: 5-Aminolevulinate Synthetase; Amino Acids; Animals; Cells, Cultured; Chick Embryo; Etiocholanolone; Heme; In Vitro Techniques; Levulinic Acids; Liver; Meprobamate; Porphobilinogen; Porphyrins; Pregnanes | 1971 |
Effect of prolonged fasting on heme metabolism in the rat.
Topics: 5-Aminolevulinate Synthetase; Animals; Chromatography, Thin Layer; Fasting; Heme; Male; Phenobarbital; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains | 1984 |
Studies on patients with polychlorinated biphenyl poisoning. 2. Determination of urinary coproporphyrin, uroporphyrin, delta-aminolevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Coproporphyrins; Heme; Humans; Polychlorinated Biphenyls; Porphobilinogen; Uroporphyrins | 1980 |
Pathogenesis and treatment of acute intermittent porphyria: discussion paper.
Topics: Acute Disease; Aminolevulinic Acid; Blood-Brain Barrier; Heme; Humans; Liver Diseases; Porphobilinogen; Porphyrias | 1983 |
Chemistry of porphyrin biosynthesis: results and applications.
Topics: Animals; Carbon Radioisotopes; Ducks; Heme; Molecular Conformation; Porphobilinogen; Porphyrins; Radioisotope Dilution Technique; Structure-Activity Relationship; Tritium; Uroporphyrinogens | 1980 |
Alterations in haem biosynthesis during the human menstrual cycle: studies in normal subjects and patients with latent and active acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases; Male; Menstruation; Middle Aged; Porphobilinogen; Porphyrias | 1982 |
[Studies on determination of Haemin -(x-) dependence in strains of genus Haemophilus based on porphobilinogen/porphyrin detection].
Topics: Haemophilus; Heme; Hemin; Humans; Porphobilinogen; Porphyrins | 1982 |
Induction of delta-aminolevulinic acid synthase and delta-aminolevulinic acid dehydratase in normal human bone marrow cultures.
Topics: 5-Aminolevulinate Synthetase; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Heme; Humans; Iron Radioisotopes; Porphobilinogen; Porphobilinogen Synthase; Time Factors | 1982 |
[Hemin treatment in a case of porphyria variegata].
Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Female; Heme; Hemin; Humans; Liver Diseases; Porphobilinogen; Porphyrias; Uroporphyrins | 1982 |
Conversion of 5-aminolaevulinate into haem by liver homogenates. Comparison of rat and chick embryo.
Topics: Aminolevulinic Acid; Animals; Chick Embryo; Ferrous Compounds; Heme; In Vitro Techniques; Kinetics; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains | 1981 |
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts.
Topics: Adult; Biopsy; Coproporphyrins; Feces; Female; Ferrochelatase; Fibroblasts; Heme; Humans; Oxidation-Reduction; Oxidoreductases; Porphobilinogen; Porphyrias; Porphyrinogens; Protoporphyrins; Skin; Uroporphyrins | 1980 |
Effect of chronic anesthesia on the drug-metabolizing enzyme system and heme pathway regulation.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anesthetics, Inhalation; Animals; Cytochrome P-450 Enzyme System; Enflurane; Heme; Hypnotics and Sedatives; Isoflurane; Liver; Male; Mice; Phenobarbital; Porphobilinogen; Porphyrins | 1997 |
The diagnosis of porphyria.
Topics: Aminolevulinic Acid; Female; Genetic Techniques; Genetic Testing; Heme; Humans; Mutation; Porphobilinogen; Porphyrias; Porphyrins | 1999 |
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Porphobilinogen; Porphyrins; Protoporphyrins | 2000 |
Hereditary coproporphyria in Germany: clinical-biochemical studies in 53 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Arginine; Child; Chromatography, High Pressure Liquid; Coproporphyrinogen Oxidase; Coproporphyrins; Feces; Female; Germany; Heme; Heterozygote; Humans; Isomerism; Male; Middle Aged; Porphobilinogen; Porphyrias, Hepatic; Uroporphyrins | 2000 |
5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Heme; Porphobilinogen; Rhodobacter sphaeroides; Succinate-CoA Ligases; Transaminases; Trypanosoma cruzi | 2003 |
Studies on the biosynthesis of blood pigments. 3. Haem and porphyrin formation from delta-aminolaevulic acid and from porphobilinogen in haemolysed chicken erythrocytes.
Topics: Animals; Biological Products; Chickens; Erythrocytes; Heme; Hemoglobins; Humans; Keto Acids; Ketones; Porphobilinogen; Porphyrins | 1956 |
[The influence of ionizing radiation on incorporation of 5-aminolevulinic acid and porphobilinogen into heme in vitro].
Topics: Amino Acids; Aminolevulinic Acid; Heme; In Vitro Techniques; Levulinic Acids; Porphobilinogen; Porphyrins; Proteins; Radiation Effects; Radiation, Ionizing | 1962 |
IN VITRO PORPHOBILINOGEN AND PORPHYRIN SYNTHESIS IN THALASSEMIA MAJOR AND SICKLE CELL ANEMIA.
Topics: Amino Acid Oxidoreductases; Anemia; Anemia, Sickle Cell; beta-Thalassemia; Heme; In Vitro Techniques; Levulinic Acids; Metabolism; Porphobilinogen; Porphyrins; Thalassemia | 1964 |
The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Biological Transport; Body Weight; Cation Transport Proteins; Drug Interactions; Duodenum; Gene Expression; Griseofulvin; Heme; In Vitro Techniques; Intestinal Absorption; Iron-Binding Proteins; Iron, Dietary; Liver; Male; Mice; Organ Size; Porphobilinogen | 2004 |
Biochemical aspects of lead exposure in silver jewelry workers in western Maharashtra (India).
Topics: Adult; Catalase; Ceruloplasmin; Enzymes; Heme; Humans; India; Lead; Lipid Peroxides; Male; Malondialdehyde; Middle Aged; Occupational Exposure; Porphobilinogen; Porphobilinogen Synthase; Protoporphyrins; Reactive Oxygen Species; Silver; Superoxide Dismutase | 2006 |
[Management of pregnancy in women with acute porphyria. Case reports].
Topics: Adult; Arginine; Female; Follow-Up Studies; Heme; Humans; Infant, Newborn; Male; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors | 2007 |
Intermittent unexplained abdominal pain: is it porphyria?
Topics: Abdominal Pain; Acute Disease; Adult; Aminolevulinic Acid; Anti-Infective Agents; Cimetidine; Contraceptives, Oral; Diet, Reducing; Enzyme Inhibitors; Female; Heme; Hemin; Humans; Liver; Liver Transplantation; Porphobilinogen; Porphyrias, Hepatic; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections | 2007 |
The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Antimicrobial Cationic Peptides; Duodenum; Enzyme Inhibitors; Heme; Hepcidins; Heptanoates; Intestinal Absorption; Iron Compounds; Male; Mice; Porphobilinogen; Porphobilinogen Synthase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Direct assay of delta-aminolevulinic acid dehydratase in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry.
Topics: Aminolevulinic Acid; Deuterium; Erythrocytes; Heme; Humans; Kinetics; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Haem arginate as effective maintenance therapy for hereditary coproporphyria.
Topics: Abdominal Pain; Adult; Arginine; Coproporphyria, Hereditary; Female; Heme; Humans; Photosensitivity Disorders; Porphobilinogen; Severity of Illness Index; Treatment Outcome | 2011 |
Methods for analysis of photosynthetic pigments and steady-state levels of intermediates of tetrapyrrole biosynthesis.
Topics: Aminolevulinic Acid; Apoenzymes; Arabidopsis; Calibration; Carotenoids; Chemistry Techniques, Analytical; Chlorophyllides; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Heme; Horseradish Peroxidase; Photosynthesis; Pigments, Biological; Porphobilinogen; Protochlorophyllide; Spectrometry, Fluorescence; Tetrapyrroles | 2011 |
Acute intermittent porphyria: fatal complications of treatment.
Topics: Abdominal Pain; Adolescent; Analgesics; Arginine; Disease Management; Fatal Outcome; Female; Hallucinations; Heme; Humans; Hyponatremia; Monitoring, Physiologic; Porphobilinogen; Porphyria, Acute Intermittent; Water-Electrolyte Balance | 2012 |
PORPHOBILINOGEN DEAMINASE deficiency alters vegetative and reproductive development and causes lesions in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Biliverdine; Chlorophyll; Gene Expression Regulation, Plant; Heme; Hydroxymethylbilane Synthase; Indoleacetic Acids; MADS Domain Proteins; Mutation; Phenotype; Plant Development; Plant Growth Regulators; Plant Leaves; Plants, Genetically Modified; Porphobilinogen; Reproduction | 2013 |
Circadian rhythms in acute intermittent porphyria--a pilot study.
Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Case-Control Studies; Circadian Clocks; Circadian Rhythm; Female; Heme; Humans; Hydrocortisone; Melatonin; Middle Aged; Pilot Projects; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger | 2013 |
Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver.
Topics: 5-Aminolevulinate Synthetase; Adult; Aminolevulinic Acid; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Liver Transplantation; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger; Uroporphyrins | 2015 |
Challenges in the successful management of a case of acute intermittent porphyria in India.
Topics: Abdominal Pain; Administration, Intravenous; Adolescent; Arginine; Heme; Humans; India; Male; Porphobilinogen; Porphyria, Acute Intermittent; Seizures; Treatment Outcome | 2016 |
Effects of volatile anaesthetics on heme metabolism in a murine genetic model of Acute Intermittent Porphyria. A comparative study with other porphyrinogenic drugs.
Topics: Anesthetics; Animals; Female; Heme; Hydroxymethylbilane Synthase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Porphobilinogen; Porphyria, Acute Intermittent; Volatile Organic Compounds | 2018 |
Sars-Cov-2 interference in HEME production: is it the time for an early predictive biomarker?
Topics: Aminolevulinic Acid; Betacoronavirus; Biomarkers; Coronavirus Infections; COVID-19; Heme; Host-Pathogen Interactions; Humans; Interleukin-6; Pandemics; Pneumonia, Viral; Porphobilinogen; SARS-CoV-2; Thrombosis; Viral Proteins | 2020 |
5-Aminolevulinate dehydratase porphyria: Update on hepatic 5-aminolevulinic acid synthase induction and long-term response to hemin.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Child; Child, Preschool; Female; Heme; Hemin; Humans; Infant; Infant, Newborn; Liver; Male; Middle Aged; Mutation; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; RNA, Messenger; Young Adult | 2020 |
Peritoneal dialysis resulting in discontinuance of recurring attacks of acute intermittent porphyria: A case report.
Topics: Aged; Heme; Humans; Male; Pain; Peritoneal Dialysis; Porphobilinogen; Porphyria, Acute Intermittent; Recurrence; Renal Dialysis | 2022 |
Bi-allelic hydroxymethylbilane synthase inactivation defines a homogenous clinico-molecular subtype of hepatocellular carcinoma.
Topics: beta Catenin; Carcinoma, Hepatocellular; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver Neoplasms; Mutation; Oxygen; Porphobilinogen; Porphyria, Acute Intermittent | 2022 |
Acute hepatic porphyrias: Recommendations for diagnosis and management with real-world examples.
Topics: Heme; Humans; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic | 2023 |