Page last updated: 2024-08-23

heme and porphobilinogen

heme has been researched along with porphobilinogen in 114 studies

Research

Studies (114)

Timeframe	Studies, this research(%)	All Research%
pre-1990	75 (65.79)	18.7374
1990's	6 (5.26)	18.2507
2000's	11 (9.65)	29.6817
2010's	15 (13.16)	24.3611
2020's	7 (6.14)	2.80

Authors

Authors	Studies
Abboud, MM; Akhtar, M; Barnard, G; Jordan, P; Zaman, Z	1
Bennett, M; Frykholm, BC; Lamon, JM; Tschudy, DP	1
Brodie, MJ; Goldberg, A; Graham, DJ; McColl, KE; Moore, MR	1
Bossenmaier, I; Cardinal, R; Pierach, CA; Watson, CJ	2
Gidari, AS; Levere, RD	1
Becker, DM; Kramer, S	1
Walsh, JR	1
Doss, M	1
Albritton, WL; Hammond, GW; Lian, CJ; Ronald, AR; Wilt, JC	1
Druschky, KF; Schaller, KH; Schwanitz, G	1
Charles, HP; McConville, ML	1
Armas Merino, R; Canals, C; Gómez, R; Monsalve, V; Wolff, C	1
Brodie, MJ; Goldberg, A; Hardie, RA; Hunter, JA; McColl, KE; Moore, MR; Thompson, GG	1
Bacheschi, LA; de Assis, JL; Do Serro-Azul, LG; Marchiori, PE; Moraes, EC; Scaff, M; Yassuda, N	1
Lithner, F	1
Goldberg, A; Ippen, H; Moore, MR; Seubert, A; Seubert, S; Thompson, GG	1
Neethling, AC; Percy, VA; Shanley, BC	1
Bossenmaier, I; Cardinal, R; Peterson, A; Watson, CJ	1
Ross, J; Sautner, D	1
Bossenmaier, I; Cardinal, R; Dhar, GJ; Petryka, ZJ; Watson, CJ	2
Watson, CJ	1
Frederickson, EL; Mees, DE	1
Morrone, G	1
Cheek, EM; Cole, RJ; Garlick, J	1
Eryürek, FG; Sürmen, E	1
el-Sharabasy, MM; el-Waseef, AM; Hafez, MM; Salim, SA	1
Goldberg, A; Herrick, AL; McColl, KE; Moore, MR; Wallace, AM	1
Aldonatti, C; San Martín de Viale, LC; Vila, MC	1
Rimington, C	1
Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Thompson, GG	1
Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Park, BK; Thompson, GG	1
Goldberg, A; Moore, MR; Yeung Laiwah, AC	1
Bissell, DM	1
Bonkovsky, HL; Healey, JF; Robinson, JM; Shedlofsky, SI; Sinclair, PR; Swim, AT	1
Arrol, S; Cutler, MG	1
Ch'ng, SL; Jeyamalar, R	1
Fuchs, T; Ippen, H	1
Lindén, IB; Tenhunen, R; Tokola, O	1
Datta, K; Shanker, J	1
Guthrie, R; Ho, J; Tieckelmann, H	1
Bernstein, M; Shivji, A	1
Doss, M; Sixel-Dietrich, F; Verspohl, F	1
Berek, I; Ivánovics, G; Miczák, A	1
Nair, PP; Solomon, D; Strummer, D	1
Meyer, UA; Schmid, R	2
Levin, EY	1
Hatch, T; Lascelles, J	1
Crispin, M; Szeinberg, A	1
Berk, PD; Berlin, NI; Bloomer, JR; Howe, RB; Jones, EA; Shrager, R	1
Embry, TL; Morgan, DP; Roan, CC	1
Amrutavalli, J; Padmanaban, G; Rajamanickam, C; Rao, MR	1
Winterhalter, KH	1
Stich, W	1
Dech, G; Fikentscher, R; Schmidt, D; Stich, W	1
Manning, J; Marver, HS; Strand, LJ	1
Burger, P; Dowdle, EB; Wilson, E	1
Doss, M; Kaltepoth, B	1
Friedland, ML; Ibraham, NG; Levere, RD	1
Atsmon, A; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N	1
Bonkowsky, HL; Schady, W	1
Chang, KJ; Lee, TP; Lu, FJ; Tung, TC	1
Goldberg, A; Laiwah, AC; Moore, MR	1
Romeo, G	1
Bock, W; Bringmann, G; Fels, G; Franck, B; Grubenbecher, F; Marsmann, M; Pietschmann, R; Schäpers, K; Spiegel, U; Steinkamp, R; Ufer, G; Wegner, C	1
Kappas, A; Sassa, S	1
Waldenström, J	1
Goldberg, A; McColl, KE; Moore, MR; Thompson, GG; Wallace, AM	1
Tiller, FW	1
Hashimoto, Y; Kondo, M; Shionoya, S; Urabe, A; Urata, G	1
Adam, C; Defresne, C; Guilmot-Bruneau, M; Hassoun, A; Saussez-De Temmerman, A; Wery-Follet, B	1
Bonkowsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR	1
Bloomer, JR; Brenner, DA	1
Urata, G	1
Buzaleh, AM; del Carmen Batlle, AM; Nuñez, G; Vazquez, ES	1
Hift, RJ	1
de Rooij, FW; Edixhoven, A; Hinnen, P; Siersema, PD; Terlouw, EM; Tilanus, HW; van Dekken, H; van Hillegersberg, R; Wilson, JH	1
Doss, MO; Gross, U; Kühnel, A	1
Elder, GH; Hift, RJ	1
Araujo, LS; Batlle, A; Lombardo, ME	1
DRESEL, EI; FALK, JE	1
DANCEWICZ, AM	1
FELDMAN, F; LICHTMAN, HC	1
Beaumont, N; Deacon, A; Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ; Solanky, N; Srai, SK	1
Herrick, AL; McColl, KE	1
Ambekar, JG; Bhagwat, VR; Das, KK; Dongre, NN; Patil, AJ; Patil, JA	1
Feder, ZM; Ignashina, EV; Karpova, IV; Kravchenko, SK; Kremenetskaia, AM; Kurtser, MA; Mironova, TS; Murashko, LE; Petrova, VI; Pustovoĭt, IaS; Pustovoĭt, LA; Shmakov, RG; Shtabnitskiĭ, AM; Sokolova, MIu	1
Bloomer, JR; McGuire, BM	1
Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ	1
Andersson, DE; Floderus, Y; Harper, P; Sardh, E	1
Choiniere, JR; Gelb, MH; Scott, CR; Turecek, F	1
Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D	1
Ma, E; Mar, V; Nicoll, A; Ross, G; Varigos, G	1
Czarnecki, O; Grimm, B; Peter, E	1
Badminton, MN; Barth, JH; Cox, TM; Rees, DC; Sarkany, R; Stein, PE; Stewart, MF	1
González-Bayón, R; Hricová, A; Micol, JL; Ponce, MR; Quesada, V; Sarmiento-Mañús, R	1
Bonkovsky, HL; Caballes, FR; Finkielstein, CV; Groseclose, G; Hwang, SI; Larion, S; Lee, JG; Li, T; Maddukuri, V; Parsons, J; Rossman, WE; Steuerwald, N	1
Anderson, KE; Arvelakis, A; Balwani, M; Chen, B; Clavero, S; Desnick, RJ; Erwin, AL; Fiel, MI; Florman, SS; Gan, L; Gordon, RE; Kadirvel, S; Liu, LU; Martin, LD; Naik, H; Phillips, JD; Sadagoparamanujam, VM; Yasuda, M; Yu, C	1
Dosi, R; Joshi, H; Patell, R; Shah, P; Tripathi, R	1
Balwani, M; Chen, B; Debnath, EM; Desnick, RJ; Doheny, D; Naik, H; Seth, A; Singh, P; Yasuda, M	1
Anderson, KE; Bissell, DM; Bonkovsky, HL	1
Barman-Aksözen, J; Huber, LC; Minder, E; Senn, JD	1
Batlle, AMDC; Buzaleh, AM; Gerez, EN; Lavandera, JV; Martínez, MDC; Oliveri, LM; Ruspini, SF; Zuccoli, JR	1
Bonkovsky, HL; Dixon, N; Rudnick, S	1
Anderson, KE	1
Comentale, G; Manzo, R; Pilato, E	1
Anderson, KE; Chan, A; Desnick, RJ; Lahiji, AP; Ramanujam, VMS; Simon, A	1
Erlandsen, EJ; Randers, E; Thomsen, HH; Østergaard, MGØ	1
Amaddeo, G; Bayard, Q; Blanc, JF; Calderaro, J; Letouzé, E; Ma, X; Molina, L; Trépo, E; Zhu, J; Zucman-Rossi, J	1
Córdoba, KM; Ena, J; Enríquez de Salamanca, R; Fontanellas, A; Jericó, D; Morales-Conejo, M; Solares, I	1
Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B	1
Anderson, KE; Dickey, A; Erwin, A; Leaf, RK; Moghe, A; O'Brien, A; Quigley, JG; Thapar, M	1

Reviews

26 review(s) available for heme and porphobilinogen

Article	Year
Enzymatic formation and cellular regulation of heme synthesis. Seminars in hematology, 1977, Volume: 14, Issue:2 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coenzyme A; Coproporphyrinogens; Enzyme Induction; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrins; Uroporphyrinogens	1977
The neurological manifestations of porphyria: a review. Medicine, 1977, Volume: 56, Issue:5 Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Liver; Liver Diseases; Nervous System; Neurologic Manifestations; Peripheral Nerves; Porphobilinogen; Porphyrias; Porphyrins	1977
Hepatic porphyrias. Current concepts. Postgraduate medicine, 1977, Volume: 62, Issue:2 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Coproporphyrinogens; Female; Genetic Diseases, Inborn; Heme; Humans; Liver Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Uroporphyrinogens	1977
[Pathobiochemistry of porphyrias]. Medizinische Klinik, 1977, Sep-23, Volume: 72, Issue:38 Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme; Humans; Liver; Liver Diseases; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins	1977
Use of hematin in the acute attack of the "inducible" hepatic prophyrias. Advances in internal medicine, 1978, Volume: 23 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Female; Heme; Hemin; Humans; Male; Middle Aged; Neurologic Manifestations; Porphobilinogen; Porphyrias; Prognosis	1978
[Chromosome studies in patients with intermittent porphyria]. Fortschritte der Medizin, 1979, Jan-18, Volume: 97, Issue:3 Topics: Adult; Aminolevulinic Acid; Chromosome Aberrations; Female; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias	1979
Haem biosynthesis and porphyrias: 50 years in retrospect. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1989, Volume: 27, Issue:8 Topics: Biochemistry; Heme; History, 20th Century; Humans; Models, Biological; Porphobilinogen; Porphyrias; Porphyrins; Retrospective Studies	1989
Pathogenesis of acute porphyria. The Quarterly journal of medicine, 1987, Volume: 63, Issue:241 Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Nervous System; Porphobilinogen; Porphyrias	1987
Intermittent acute porphyria: the enzymatic defect. Research publications - Association for Research in Nervous and Mental Disease, 1974, Volume: 53 Topics: 5-Aminolevulinate Synthetase; Adenosine Triphosphatases; Alanine; Aminolevulinic Acid; Ammonia-Lyases; Dysautonomia, Familial; Heme; Humans; Liver; Porphobilinogen; Porphyrias; Porphyrins	1974
[Hepatic porphyrias]. Harefuah, 1972, Feb-01, Volume: 82, Issue:3 Topics: Animals; Heme; Humans; Levulinic Acids; Liver; Porphobilinogen; Porphyrias; Porphyrins	1972
Heme metabolism in erythroid and hepatic cells. Progress in hematology, 1983, Volume: 13 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrinogen Oxidase; Erythrocytes; Erythropoiesis; Ferrochelatase; Flavoproteins; Heme; Heme Oxygenase (Decyclizing); Humans; Liver; Liver Diseases; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase; Uroporphyrinogen III Synthetase	1983
Neurologic manifestations of acute porphyria. Seminars in liver disease, 1982, Volume: 2, Issue:2 Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Heme; Humans; Light; Liver Diseases; Muscle Hypotonia; Nerve Fibers; Nerve Fibers, Myelinated; Nervous System Diseases; Pain, Intractable; Peripheral Nerves; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Prognosis; Seizures; Vitamin B 6 Deficiency; Zinc	1982
The hepatic porphyrias. Progress in medical genetics, 1980, Volume: 4 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Gene Expression Regulation; Heme; Humans; Infant; Liver; Liver Diseases; Male; Middle Aged; Photosensitivity Disorders; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Porphyrins; Prenatal Diagnosis; Protoporphyria, Erythropoietic; Recurrence; Skin Diseases	1980
Genetic, metabolic, and biochemical aspects of the porphyrias. Advances in human genetics, 1981, Volume: 11 Topics: Aminolevulinic Acid; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Erythrocytes; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrinogens; Porphyrins; Rodent Diseases; Sciuridae; Swine; Swine Diseases	1981
The porphyrias--a review. Haematologia, 1981, Volume: 14, Issue:3 Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Diseases; Male; Porphobilinogen; Porphyrias; Skin Diseases; Time Factors	1981
[The chemistry of porphyrins and their precursors on the heme biosynthetic chain]. Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53, Issue:6 Topics: Aminolevulinic Acid; Heme; Humans; Porphobilinogen; Porphyrins; Uroporphyrinogens	1995
Treatment of acute porphyria. Hospital medicine (London, England : 1998), 2001, Volume: 62, Issue:7 Topics: Adolescent; Adult; Analgesics, Opioid; Arginine; Clinical Trials as Topic; Dietary Carbohydrates; Female; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Pregnancy; Pregnancy Complications; Treatment Outcome	2001
Acute intermittent porphyria. Best practice & research. Clinical gastroenterology, 2005, Volume: 19, Issue:2 Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Humans; Porphobilinogen; Porphyria, Acute Intermittent	2005
Porphyrias at a glance: diagnosis and treatment. Internal and emergency medicine, 2010, Volume: 5 Suppl 1 Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrins	2010
Acute Intermittent Porphyria in children: A case report and review of the literature. Molecular genetics and metabolism, 2016, Volume: 119, Issue:4 Topics: Child; Female; Genetic Testing; Heme; Humans; Hydroxymethylbilane Synthase; Male; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; RNA Splice Sites; Seizures	2016
Porphyria. The New England journal of medicine, 2017, Aug-31, Volume: 377, Issue:9 Topics: Female; Heme; Hemin; Humans; Male; Phlebotomy; Porphobilinogen; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyrins; Prognosis; Protoporphyria, Erythropoietic; RNA, Small Interfering; Sunlight; Symptom Assessment	2017
[CME: Acute Intermittent Porphyria: When to Think of It? What Must be Checked? How to Treat?] Praxis, 2018, Volume: 107, Issue:3 Topics: Arginine; Combined Modality Therapy; Diagnosis, Differential; Female; Genetic Predisposition to Disease; Heme; Hemin; Humans; Interdisciplinary Communication; Intersectoral Collaboration; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Prognosis; Recurrence; Risk Factors	2018
Pathogenesis and clinical features of the acute hepatic porphyrias (AHPs). Molecular genetics and metabolism, 2019, Volume: 128, Issue:3 Topics: Anxiety; Heme; Humans; Mutation; Neuralgia; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic; Sleep Initiation and Maintenance Disorders	2019
Acute hepatic porphyrias: Current diagnosis & management. Molecular genetics and metabolism, 2019, Volume: 128, Issue:3 Topics: Animals; Biosynthetic Pathways; Clinical Trials as Topic; Disease Management; Heme; Hemin; Humans; Mice; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic	2019
Understanding Carbohydrate Metabolism and Insulin Resistance in Acute Intermittent Porphyria. International journal of molecular sciences, 2022, Dec-20, Volume: 24, Issue:1 Topics: Aminolevulinic Acid; Animals; Carbohydrate Metabolism; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Insulin; Insulin Resistance; Mice; Porphobilinogen; Porphyria, Acute Intermittent	2022
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. Gastroenterology, 2023, Volume: 164, Issue:3 Topics: Abdominal Pain; Aminolevulinic Acid; Antiemetics; Carcinoma, Hepatocellular; Creatinine; Female; Heme; Hemin; Humans; Hypertension; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; Quality of Life; Renal Insufficiency, Chronic; United States	2023

Trials

2 trial(s) available for heme and porphobilinogen

Article	Year
Effects of sodium valproate on haem biosynthesis in man: implications for seizure management in the porphyric patient. European journal of clinical investigation, 1988, Volume: 18, Issue:1 Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Drug Administration Schedule; Epilepsy; Female; Heme; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Valproic Acid	1988
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks. European journal of internal medicine, 2009, Volume: 20, Issue:2 Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug Monitoring; Female; Glucose; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity	2009

Article

Year

Effects of sodium valproate on haem biosynthesis in man: implications for seizure management in the porphyric patient.

European journal of clinical investigation, 1988, Volume: 18, Issue:1

Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Drug Administration Schedule; Epilepsy; Female; Heme; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Valproic Acid

1988

Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.

European journal of internal medicine, 2009, Volume: 20, Issue:2

Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug Monitoring; Female; Glucose; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity

2009

Other Studies

86 other study(ies) available for heme and porphobilinogen

Article	Year
Mechanism and stereochemistry of enzymic reactions involved in porphyrin biosynthesis. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1976, Feb-05, Volume: 273, Issue:924 Topics: 5-Aminolevulinate Synthetase; Carboxy-Lyases; Glycine; Heme; Porphobilinogen; Porphyrins; Stereoisomerism; Uroporphyrinogen Decarboxylase; Vinyl Compounds	1976
Prevention of acute porphyric attacks by intravenous haematin. Lancet (London, England), 1978, Sep-02, Volume: 2, Issue:8088 Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Pressure; Circadian Rhythm; Drug Evaluation; Female; Heme; Hemin; Humans; Infusions, Parenteral; Menstruation; Porphobilinogen; Porphyrias; Pulse; Remission, Spontaneous	1978
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria. European journal of clinical investigation, 1979, Volume: 9, Issue:1 Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinogen; Porphyrias; Pyrroles	1979
Postulated deficiency of hepatic heme and repair by hematin infusions in the "inducible" hepatic porphyrias. Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:5 Topics: 5-Aminolevulinate Synthetase; Adult; Female; Heme; Hemin; Humans; Liver; Male; Porphobilinogen; Porphyrias	1977
Determination of the hemin requirement of Haemophilus ducreyi: evaluation of the porphyrin test and media used in the satellite growth test. Journal of clinical microbiology, 1978, Volume: 7, Issue:3 Topics: Bacteriological Techniques; Culture Media; Factor X; Haemophilus ducreyi; Heme; Hemin; Porphobilinogen; Porphyrins	1978
Mutants of Escherichia coli K12 accumulating porphobilinogen: a new locus, hemC. Journal of general microbiology, 1979, Volume: 111, Issue:1 Topics: Chromosome Mapping; Escherichia coli; Genes; Heme; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; Transduction, Genetic	1979
[Effect of hematin in acute porphyric relapse]. Revista medica de Chile, 1979, Volume: 107, Issue:1 Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Heme; Hemin; Humans; Male; Porphobilinogen; Porphyrias; Uroporphyrins	1979
Haem biosynthesis in cutaneous hepatic porphyria: comparison with alcoholism and liver disease. Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:2 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases, Alcoholic; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase	1979
[Hematin treatment of acute intermittent porphyria. A case report (author's transl)]. Revista brasileira de pesquisas medicas e biologicas, 1979, Volume: 12, Issue:4-5 Topics: Adolescent; Aminolevulinic Acid; Antihypertensive Agents; Electromyography; Female; Heme; Hemin; Humans; Infusions, Parenteral; Lung; Porphobilinogen; Porphyrias	1979
[Acute intermittent porphyria--a clinical review]. Lakartidningen, 1979, Dec-26, Volume: 76, Issue:52 Topics: Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Heme; Humans; Porphobilinogen; Porphyrias	1979
The biosynthesis of haem in congenital (erythropoietic) porphyria. The International journal of biochemistry, 1978, Volume: 9, Issue:12 Topics: 5-Aminolevulinate Synthetase; Adult; Child; Child, Preschool; Coproporphyrinogens; Erythrocytes; Erythropoiesis; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrinogens	1978
Pathogenesis of neural manifestations in acute porphyria. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Apr-02, Volume: 51, Issue:14 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Anura; Brain; Heme; Humans; In Vitro Techniques; Mice; Neurologic Manifestations; Porphobilinogen; Porphyrias; Rats	1977
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse. JAMA, 1976, Feb-02, Volume: 235, Issue:5 Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Heme; Hemin; Humans; Infusions, Parenteral; Porphobilinogen; Porphyrias; Remission, Spontaneous	1976
Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells. Cell, 1976, Volume: 8, Issue:4 Topics: Aminolevulinic Acid; Biliverdine; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Erythropoiesis; Globins; Heme; Hemin; Hemoglobins; Kinetics; Porphobilinogen; RNA, Messenger; RNA, Neoplasm	1976
Effects of hematin in hepatic porphyria. Further studies. Annals of internal medicine, 1975, Volume: 83, Issue:1 Topics: Adult; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Recurrence	1975
Editorial: Hematin and porphyria. The New England journal of medicine, 1975, Sep-18, Volume: 293, Issue:12 Topics: 5-Aminolevulinate Synthetase; Adult; Animals; Female; Heme; Hemin; Humans; Kidney Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Rabbits; Rats	1975
Anesthesia and the porphyrias. Southern medical journal, 1975, Volume: 68, Issue:1 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Anesthesia; Anesthetics; Child; Chlordiazepoxide; Cytochrome P-450 Enzyme System; Demyelinating Diseases; Diazepam; Heme; Humans; Neostigmine; Pentazocine; Porphobilinogen; Porphyrias; Thiopental	1975
[The etiopathogenesis and clinical classification of congenital and acquired porphyrias]. La Pediatria, 1975, Jun-30, Volume: 83, Issue:2 Topics: Animals; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrinogens; Porphyrins	1975
Activities of haem synthetic enzymes in blood cells of pre-natal flexed-tailed (f/f) anaemic mice. Journal of embryology and experimental morphology, 1975, Volume: 34, Issue:2 Topics: 5-Aminolevulinate Synthetase; Anemia; Animals; Erythrocytes; Fetal Blood; Heme; Iron; Liver; Lyases; Mice; Mice, Inbred Strains; Mutation; Porphobilinogen; Porphobilinogen Synthase; Porphyrinogens; Porphyrins; Reticulocytes	1975
Liver delta-aminolevulinate dehydratase activity in amitriptyline- or chlorpromazine-treated rats. Toxicology, 1992, Volume: 75, Issue:1 Topics: Amitriptyline; Animals; Chlorpromazine; Heme; Liver; Male; Porphobilinogen; Porphobilinogen Synthase; Rats; Rats, Wistar	1992
Porphyrin metabolism in some malignant diseases. British journal of cancer, 1992, Volume: 65, Issue:3 Topics: Adult; Aminolevulinic Acid; Child; Coproporphyrins; Erythrocytes; Female; Ferrochelatase; Heme; Hodgkin Disease; Humans; Hydroxymethylbilane Synthase; Lymphoma, Non-Hodgkin; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uroporphyrins	1992
Elevation of hormone-binding globulins in acute intermittent porphyria. Clinica chimica acta; international journal of clinical chemistry, 1990, Feb-28, Volume: 187, Issue:2 Topics: Adolescent; Adult; Aminolevulinic Acid; Arginine; Carrier Proteins; Heme; Humans; Hydrocortisone; Liver Diseases; Porphobilinogen; Porphyrias; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Thyroxine-Binding Proteins	1990
[Evaluation of porphyrinogenic effect of lindane in rats]. Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1986, Volume: 36, Issue:1 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Heme; Hexachlorocyclohexane; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains	1986
The effects of chronic carbamazepine treatment of haem biosynthesis in man and rat. European journal of clinical pharmacology, 1988, Volume: 35, Issue:3 Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Animals; Carbamazepine; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats; Rats, Inbred Strains	1988
Treatment of acute hepatic porphyria with hematin. Journal of hepatology, 1988, Volume: 6, Issue:1 Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Liver Diseases; Male; Middle Aged; Porphobilinogen; Porphyrias	1988
Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450. The Biochemical journal, 1987, Nov-15, Volume: 248, Issue:1 Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Heme; Levulinic Acids; Liver; Methylcholanthrene; Porphobilinogen; Porphyrins	1987
Pharmacological effects of haem biosynthetic intermediates in isolated intestinal preparations. European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3 Topics: Aminolevulinic Acid; Animals; Colon; Coproporphyrins; Female; Glycine; Heme; Hemin; In Vitro Techniques; Intestinal Mucosa; Intestines; Jejunum; Male; Muscle Contraction; Porphobilinogen; Protoporphyrins; Rabbits; Succinates	1987
Acute intermittent porphyria: the first case report in Malaysia. Singapore medical journal, 1986, Volume: 27, Issue:6 Topics: Acute Disease; Adult; Female; Heme; Humans; Malaysia; Porphobilinogen; Porphyrias	1986
[Treatment of acute intermittent porphyria with a new protein-bound lyophilized hematin]. Deutsche medizinische Wochenschrift (1946), 1987, Aug-21, Volume: 112, Issue:34 Topics: Acute Disease; Adult; Female; Freeze Drying; Heme; Hemin; Humans; Porphobilinogen; Porphyrias; Protein Binding	1987
The effects of haem arginate and haematin upon the allylisopropylacetamide induced experimental porphyria in rats. Pharmacology & toxicology, 1987, Volume: 61, Issue:1 Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Arginine; Heme; Hemin; Liver; Male; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains	1987
Affinity purification and properties of rat liver mitochondrial L-alanine:4,5-dioxovalerate transaminase and its inhibition by hemin. Archives of biochemistry and biophysics, 1986, Aug-01, Volume: 248, Issue:2 Topics: Animals; Bilirubin; Chromatography, Affinity; Heme; Hemin; Kinetics; Male; Mitochondria, Liver; Molecular Weight; Porphobilinogen; Protoporphyrins; Rats; Spectrum Analysis; Transaminases	1986
Detection of delta-aminolevulinic acid, porphobilinogen and porphyrins related to heme biosynthesis by high-performance liquid chromatography. Journal of chromatography, 1986, Feb-14, Volume: 375, Issue:1 Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Levulinic Acids; o-Phthalaldehyde; Porphobilinogen; Porphyrins	1986
Stimulation of 5-aminolevulinic acid metabolism by uroporphyrinogen I in rat liver homogenate. Clinical biochemistry, 1985, Volume: 18, Issue:2 Topics: Aminolevulinic Acid; Animals; Cell-Free System; Heme; In Vitro Techniques; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrinogens; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrinogens	1985
"Glucose effect" and rate limiting function of uroporphyrinogen synthase on porphyrin metabolism in hepatocyte culture: relationship with human acute hepatic porphyrias. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1985, Volume: 23, Issue:9 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Cells, Cultured; Chick Embryo; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Kinetics; Liver; Liver Diseases; Meprobamate; Porphobilinogen; Porphyrias; Porphyrins	1985
Mapping the delta-aminolaevulinic acid dehydrase and porphobilinogen deaminase loci in Bacillus subtilis. Molecular & general genetics : MGG, 1974, Volume: 132, Issue:3 Topics: Ammonia-Lyases; Bacillus subtilis; Bacteriophages; Chromosome Mapping; Crosses, Genetic; Crossing Over, Genetic; Deamination; Genotype; Heme; Hydro-Lyases; Porphobilinogen; Porphobilinogen Synthase; Recombination, Genetic; Transduction, Genetic	1974
Relationship between vitamin E and urinary excretion of ketosteroid fractions in cystic mastitis. Annals of the New York Academy of Sciences, 1972, Dec-18, Volume: 203 Topics: 17-Ketosteroids; Adult; Androsterone; Chronic Disease; Cysts; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Female; Heme; Hemeproteins; Humans; Levulinic Acids; Mastitis; Menstruation; Middle Aged; Ovulation; Porphobilinogen; Porphyrins; Pregnancy; Pregnanes; Pregnanetriol; Vitamin E	1972
Comparative aspects of porphyria in man and animals. Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0 Topics: Adult; Aminolevulinic Acid; Animals; Cattle; Drug Stability; Female; Genes, Recessive; Heme; Heterozygote; Hot Temperature; Humans; Isomerases; Kinetics; Male; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Reticulocytes; Sciuridae	1974
Accumulation of porphobilinogen and other pyrroles by mutant and wild type Rhodopseudomonas spheroides: regulation by heme. Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:1 Topics: 5-Aminolevulinate Synthetase; Carboxy-Lyases; Chlorophyll; Feedback; Genetics, Microbial; Heme; Hydro-Lyases; Iron; Iron Isotopes; Levulinic Acids; Mutation; Phenanthrolines; Porphobilinogen; Porphyrins; Propionates; Puromycin; Pyrroles; Rhodobacter sphaeroides; Rhodopseudomonas	1972
Quantitative studies of the delivery of hepatic-synthesized bilirubin to plasma utilizing -aminolevulinic acid-4- 14 C and bilirubin- 3 H in man. The Journal of clinical investigation, 1972, Volume: 51, Issue:9 Topics: Adult; Bile Pigments; Bilirubin; Carbon Isotopes; Chromium Isotopes; Feces; Hematocrit; Heme; Humans; Injections, Intravenous; Levulinic Acids; Liver; Mathematics; Methods; Porphobilinogen; Porphyrias; Porphyrins; Time Factors; Tritium	1972
Search for abnormalities of heme synthesis and sympathoadrenal activity--in workers regularly exposed to pesticides. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1972, Volume: 14, Issue:12 Topics: Adrenal Glands; Arizona; Catecholamines; Cholinesterases; Chromatography, Gas; DDT; Dieldrin; Environmental Exposure; Heme; Humans; Insecticides; Levulinic Acids; Nitrophenols; Occupational Diseases; Parathion; Pesticide Residues; Pesticides; Porphobilinogen; Porphyrins; Sympathetic Nervous System; Toxaphene	1972
Effect of hexachlorobenzene on haem synthesis. The Biochemical journal, 1972, Volume: 129, Issue:2 Topics: 5-Aminolevulinate Synthetase; Amino Acids; Animals; Benzene Derivatives; Cells, Cultured; Chlorine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Half-Life; Heme; Hydro-Lyases; In Vitro Techniques; Insecticides; Liver; Microsomes, Liver; Organ Size; Plants; Porphobilinogen; Porphyrias; Porphyrins; Rats	1972
Structure and synthesis of heme and references to globin synthesis. Hamatologie und Bluttransfusion, 1972, Volume: 10 Topics: 5-Aminolevulinate Synthetase; Globins; Heme; Iron; Levulinic Acids; Metabolism, Inborn Errors; Peptide Chain Initiation, Translational; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins; Protein Conformation	1972
[Clinically important disorders of heme synthesis]. Hamatologie und Bluttransfusion, 1972, Volume: 10 Topics: 5-Aminolevulinate Synthetase; Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Erythrocytes; Heme; Humans; Iron; Porphobilinogen; Porphyrias; Porphyrins	1972
Hereditary hepatic porphyrias. Federation proceedings, 1973, Volume: 32, Issue:6 Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Cytochrome P-450 Enzyme System; Erythrocytes; Heme; Humans; Liver; Microsomes, Liver; Porphobilinogen; Porphyrias	1973
Effect of hematin in acute porphyric relapse. Annals of internal medicine, 1973, Volume: 79, Issue:1 Topics: 5-Aminolevulinate Synthetase; Adult; Alcohol Drinking; Heme; Humans; Injections, Intravenous; Male; Porphobilinogen; Porphyrias; Porphyrins; Substance-Related Disorders	1973
[Fetal heme synthesis in various stages of blood formation]. Blut, 1972, Volume: 25, Issue:2 Topics: Chromatography, Thin Layer; Erythrocytes; Fetus; Hematopoiesis; Heme; Humans; Hydro-Lyases; Levulinic Acids; Liver; Porphobilinogen; Porphyrins; Reticulocytes; Spleen	1972
Acute intermittent porphyria: studies of the enzymatic basis of disordered haem biosynthesis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Sep-25 Topics: 5-Aminolevulinate Synthetase; Acute Disease; Acyltransferases; Animals; Birds; Heme; Humans; In Vitro Techniques; Liver; Lyases; Porphobilinogen; Porphyrias; Porphyrins	1971
Symptomatic porphyria I. The effects of lead on the synthesis of porphyrin and haem. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Sep-25 Topics: Adult; Amino Acids; Animals; Chickens; Erythrocytes; Heme; Humans; Hydro-Lyases; Lead; Lead Poisoning; Levulinic Acids; Male; Middle Aged; Porphobilinogen; Porphyrins	1971
Porphyrin biosynthesis in liver cell cultures. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Sep-25 Topics: 5-Aminolevulinate Synthetase; Amino Acids; Animals; Cells, Cultured; Chick Embryo; Etiocholanolone; Heme; In Vitro Techniques; Levulinic Acids; Liver; Meprobamate; Porphobilinogen; Porphyrins; Pregnanes	1971
Effect of prolonged fasting on heme metabolism in the rat. Israel journal of medical sciences, 1984, Volume: 20, Issue:3 Topics: 5-Aminolevulinate Synthetase; Animals; Chromatography, Thin Layer; Fasting; Heme; Male; Phenobarbital; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains	1984
Studies on patients with polychlorinated biphenyl poisoning. 2. Determination of urinary coproporphyrin, uroporphyrin, delta-aminolevulinic acid and porphobilinogen. Research communications in chemical pathology and pharmacology, 1980, Volume: 30, Issue:3 Topics: Aminolevulinic Acid; Coproporphyrins; Heme; Humans; Polychlorinated Biphenyls; Porphobilinogen; Uroporphyrins	1980
Pathogenesis and treatment of acute intermittent porphyria: discussion paper. Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:5 Topics: Acute Disease; Aminolevulinic Acid; Blood-Brain Barrier; Heme; Humans; Liver Diseases; Porphobilinogen; Porphyrias	1983
Chemistry of porphyrin biosynthesis: results and applications. The International journal of biochemistry, 1980, Volume: 12, Issue:5-6 Topics: Animals; Carbon Radioisotopes; Ducks; Heme; Molecular Conformation; Porphobilinogen; Porphyrins; Radioisotope Dilution Technique; Structure-Activity Relationship; Tritium; Uroporphyrinogens	1980
Alterations in haem biosynthesis during the human menstrual cycle: studies in normal subjects and patients with latent and active acute intermittent porphyria. Clinical science (London, England : 1979), 1982, Volume: 62, Issue:2 Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases; Male; Menstruation; Middle Aged; Porphobilinogen; Porphyrias	1982
[Studies on determination of Haemin -(x-) dependence in strains of genus Haemophilus based on porphobilinogen/porphyrin detection]. Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1982, Volume: 28, Issue:2 Topics: Haemophilus; Heme; Hemin; Humans; Porphobilinogen; Porphyrins	1982
Induction of delta-aminolevulinic acid synthase and delta-aminolevulinic acid dehydratase in normal human bone marrow cultures. Stem cells, 1982, Volume: 2, Issue:3 Topics: 5-Aminolevulinate Synthetase; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Heme; Humans; Iron Radioisotopes; Porphobilinogen; Porphobilinogen Synthase; Time Factors	1982
[Hemin treatment in a case of porphyria variegata]. Dermatologica, 1982, Volume: 165, Issue:6 Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Female; Heme; Hemin; Humans; Liver Diseases; Porphobilinogen; Porphyrias; Uroporphyrins	1982
Conversion of 5-aminolaevulinate into haem by liver homogenates. Comparison of rat and chick embryo. The Biochemical journal, 1981, Sep-15, Volume: 198, Issue:3 Topics: Aminolevulinic Acid; Animals; Chick Embryo; Ferrous Compounds; Heme; In Vitro Techniques; Kinetics; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains	1981
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts. The New England journal of medicine, 1980, Apr-03, Volume: 302, Issue:14 Topics: Adult; Biopsy; Coproporphyrins; Feces; Female; Ferrochelatase; Fibroblasts; Heme; Humans; Oxidation-Reduction; Oxidoreductases; Porphobilinogen; Porphyrias; Porphyrinogens; Protoporphyrins; Skin; Uroporphyrins	1980
Effect of chronic anesthesia on the drug-metabolizing enzyme system and heme pathway regulation. General pharmacology, 1997, Volume: 28, Issue:4 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anesthetics, Inhalation; Animals; Cytochrome P-450 Enzyme System; Enflurane; Heme; Hypnotics and Sedatives; Isoflurane; Liver; Male; Mice; Phenobarbital; Porphobilinogen; Porphyrins	1997
The diagnosis of porphyria. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1999, Volume: 89, Issue:6 Topics: Aminolevulinic Acid; Female; Genetic Techniques; Genetic Testing; Heme; Humans; Mutation; Porphobilinogen; Porphyrias; Porphyrins	1999
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid. British journal of cancer, 2000, Volume: 83, Issue:4 Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Porphobilinogen; Porphyrins; Protoporphyrins	2000
Hereditary coproporphyria in Germany: clinical-biochemical studies in 53 patients. Clinical biochemistry, 2000, Volume: 33, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Arginine; Child; Chromatography, High Pressure Liquid; Coproporphyrinogen Oxidase; Coproporphyrins; Feces; Female; Germany; Heme; Heterozygote; Humans; Isomerism; Male; Middle Aged; Porphobilinogen; Porphyrias, Hepatic; Uroporphyrins	2000
5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi. The international journal of biochemistry & cell biology, 2003, Volume: 35, Issue:8 Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Heme; Porphobilinogen; Rhodobacter sphaeroides; Succinate-CoA Ligases; Transaminases; Trypanosoma cruzi	2003
Studies on the biosynthesis of blood pigments. 3. Haem and porphyrin formation from delta-aminolaevulic acid and from porphobilinogen in haemolysed chicken erythrocytes. The Biochemical journal, 1956, Volume: 63, Issue:1 Topics: Animals; Biological Products; Chickens; Erythrocytes; Heme; Hemoglobins; Humans; Keto Acids; Ketones; Porphobilinogen; Porphyrins	1956
[The influence of ionizing radiation on incorporation of 5-aminolevulinic acid and porphobilinogen into heme in vitro]. Postepy biochemii, 1962, Volume: 8 Topics: Amino Acids; Aminolevulinic Acid; Heme; In Vitro Techniques; Levulinic Acids; Porphobilinogen; Porphyrins; Proteins; Radiation Effects; Radiation, Ionizing	1962
IN VITRO PORPHOBILINOGEN AND PORPHYRIN SYNTHESIS IN THALASSEMIA MAJOR AND SICKLE CELL ANEMIA. Annals of the New York Academy of Sciences, 1964, Oct-07, Volume: 119 Topics: Amino Acid Oxidoreductases; Anemia; Anemia, Sickle Cell; beta-Thalassemia; Heme; In Vitro Techniques; Levulinic Acids; Metabolism; Porphobilinogen; Porphyrins; Thalassemia	1964
The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption. Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:4 Topics: Administration, Oral; Aminolevulinic Acid; Animals; Biological Transport; Body Weight; Cation Transport Proteins; Drug Interactions; Duodenum; Gene Expression; Griseofulvin; Heme; In Vitro Techniques; Intestinal Absorption; Iron-Binding Proteins; Iron, Dietary; Liver; Male; Mice; Organ Size; Porphobilinogen	2004
Biochemical aspects of lead exposure in silver jewelry workers in western Maharashtra (India). Journal of basic and clinical physiology and pharmacology, 2006, Volume: 17, Issue:4 Topics: Adult; Catalase; Ceruloplasmin; Enzymes; Heme; Humans; India; Lead; Lipid Peroxides; Male; Malondialdehyde; Middle Aged; Occupational Exposure; Porphobilinogen; Porphobilinogen Synthase; Protoporphyrins; Reactive Oxygen Species; Silver; Superoxide Dismutase	2006
[Management of pregnancy in women with acute porphyria. Case reports]. Terapevticheskii arkhiv, 2007, Volume: 79, Issue:8 Topics: Adult; Arginine; Female; Follow-Up Studies; Heme; Humans; Infant, Newborn; Male; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors	2007
Intermittent unexplained abdominal pain: is it porphyria? Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:11 Topics: Abdominal Pain; Acute Disease; Adult; Aminolevulinic Acid; Anti-Infective Agents; Cimetidine; Contraceptives, Oral; Diet, Reducing; Enzyme Inhibitors; Female; Heme; Hemin; Humans; Liver; Liver Transplantation; Porphobilinogen; Porphyrias, Hepatic; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections	2007
The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities. Toxicology and applied pharmacology, 2008, Jun-15, Volume: 229, Issue:3 Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Antimicrobial Cationic Peptides; Duodenum; Enzyme Inhibitors; Heme; Hepcidins; Heptanoates; Intestinal Absorption; Iron Compounds; Male; Mice; Porphobilinogen; Porphobilinogen Synthase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2008
Direct assay of delta-aminolevulinic acid dehydratase in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Analytical chemistry, 2010, Aug-01, Volume: 82, Issue:15 Topics: Aminolevulinic Acid; Deuterium; Erythrocytes; Heme; Humans; Kinetics; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2010
Haem arginate as effective maintenance therapy for hereditary coproporphyria. The Australasian journal of dermatology, 2011, Volume: 52, Issue:2 Topics: Abdominal Pain; Adult; Arginine; Coproporphyria, Hereditary; Female; Heme; Humans; Photosensitivity Disorders; Porphobilinogen; Severity of Illness Index; Treatment Outcome	2011
Methods for analysis of photosynthetic pigments and steady-state levels of intermediates of tetrapyrrole biosynthesis. Methods in molecular biology (Clifton, N.J.), 2011, Volume: 775 Topics: Aminolevulinic Acid; Apoenzymes; Arabidopsis; Calibration; Carotenoids; Chemistry Techniques, Analytical; Chlorophyllides; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Heme; Horseradish Peroxidase; Photosynthesis; Pigments, Biological; Porphobilinogen; Protochlorophyllide; Spectrometry, Fluorescence; Tetrapyrroles	2011
Acute intermittent porphyria: fatal complications of treatment. Clinical medicine (London, England), 2012, Volume: 12, Issue:3 Topics: Abdominal Pain; Adolescent; Analgesics; Arginine; Disease Management; Fatal Outcome; Female; Hallucinations; Heme; Humans; Hyponatremia; Monitoring, Physiologic; Porphobilinogen; Porphyria, Acute Intermittent; Water-Electrolyte Balance	2012
PORPHOBILINOGEN DEAMINASE deficiency alters vegetative and reproductive development and causes lesions in Arabidopsis. PloS one, 2013, Volume: 8, Issue:1 Topics: Arabidopsis; Arabidopsis Proteins; Biliverdine; Chlorophyll; Gene Expression Regulation, Plant; Heme; Hydroxymethylbilane Synthase; Indoleacetic Acids; MADS Domain Proteins; Mutation; Phenotype; Plant Development; Plant Growth Regulators; Plant Leaves; Plants, Genetically Modified; Porphobilinogen; Reproduction	2013
Circadian rhythms in acute intermittent porphyria--a pilot study. European journal of clinical investigation, 2013, Volume: 43, Issue:7 Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Case-Control Studies; Circadian Clocks; Circadian Rhythm; Female; Heme; Humans; Hydrocortisone; Melatonin; Middle Aged; Pilot Projects; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger	2013
Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver. Molecular medicine (Cambridge, Mass.), 2015, Jun-05, Volume: 21 Topics: 5-Aminolevulinate Synthetase; Adult; Aminolevulinic Acid; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Liver Transplantation; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger; Uroporphyrins	2015
Challenges in the successful management of a case of acute intermittent porphyria in India. Tropical doctor, 2016, Volume: 46, Issue:3 Topics: Abdominal Pain; Administration, Intravenous; Adolescent; Arginine; Heme; Humans; India; Male; Porphobilinogen; Porphyria, Acute Intermittent; Seizures; Treatment Outcome	2016
Effects of volatile anaesthetics on heme metabolism in a murine genetic model of Acute Intermittent Porphyria. A comparative study with other porphyrinogenic drugs. Biochimica et biophysica acta. General subjects, 2018, Volume: 1862, Issue:6 Topics: Anesthetics; Animals; Female; Heme; Hydroxymethylbilane Synthase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Porphobilinogen; Porphyria, Acute Intermittent; Volatile Organic Compounds	2018
Sars-Cov-2 interference in HEME production: is it the time for an early predictive biomarker? Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:8 Topics: Aminolevulinic Acid; Betacoronavirus; Biomarkers; Coronavirus Infections; COVID-19; Heme; Host-Pathogen Interactions; Humans; Interleukin-6; Pandemics; Pneumonia, Viral; Porphobilinogen; SARS-CoV-2; Thrombosis; Viral Proteins	2020
5-Aminolevulinate dehydratase porphyria: Update on hepatic 5-aminolevulinic acid synthase induction and long-term response to hemin. Molecular genetics and metabolism, 2020, Volume: 131, Issue:4 Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Child; Child, Preschool; Female; Heme; Hemin; Humans; Infant; Infant, Newborn; Liver; Male; Middle Aged; Mutation; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; RNA, Messenger; Young Adult	2020
Peritoneal dialysis resulting in discontinuance of recurring attacks of acute intermittent porphyria: A case report. Seminars in dialysis, 2022, Volume: 35, Issue:1 Topics: Aged; Heme; Humans; Male; Pain; Peritoneal Dialysis; Porphobilinogen; Porphyria, Acute Intermittent; Recurrence; Renal Dialysis	2022
Bi-allelic hydroxymethylbilane synthase inactivation defines a homogenous clinico-molecular subtype of hepatocellular carcinoma. Journal of hepatology, 2022, Volume: 77, Issue:4 Topics: beta Catenin; Carcinoma, Hepatocellular; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver Neoplasms; Mutation; Oxygen; Porphobilinogen; Porphyria, Acute Intermittent	2022
Acute hepatic porphyrias: Recommendations for diagnosis and management with real-world examples. Molecular genetics and metabolism, 2023, Volume: 140, Issue:3 Topics: Heme; Humans; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic	2023