Compounds > heme
Page last updated: 2024-08-23

heme and mifepristone

heme has been researched along with mifepristone in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonkovsky, HL; Cable, EE; Donohue, SE; Lambrecht, RW; Pepe, JA1
He, K; Hollenberg, PF; Woolf, TF1
Hollenberg, PF; Lin, HL; Zhang, H1

Other Studies

3 other study(ies) available for heme and mifepristone

ArticleYear
Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria.
    European journal of biochemistry, 1994, Oct-15, Volume: 225, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Heme; Liver; Mifepristone; Porphyrias, Hepatic; Porphyrins; RNA, Messenger

1994
Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2

    Topics: Abortifacient Agents, Steroidal; Animals; Apoenzymes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Heme; Humans; Kinetics; Male; Mifepristone; Mixed Function Oxygenases; NADP; Rats; Rats, Inbred F344; Sodium Dodecyl Sulfate; Spectrum Analysis; Testosterone

1999
Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Animals; Apoproteins; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Crystallization; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glutathione; Heme; Hormone Antagonists; Humans; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Mifepristone; NADP; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry

2009