heme has been researched along with metyrapone in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebel, RE; O'keeffe, DH; Peterson, JA | 1 |
| McDonagh, AF; Schmid, R | 1 |
| Simonet, L; Williams, MT | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H | 1 |
| Macdonald, ID; Munro, AW; Smith, WE | 1 |
| Angove, HC; Cosme, J; Day, PJ; Jhoti, H; Tickle, IJ; Vinkovic, DM; Vonrhein, C; Ward, A; Williams, PA | 1 |
| Balding, PR; de Visser, SP; Maréchal, JD; McLean, KJ; Munro, AW; Porro, CS; Sutcliffe, MJ | 1 |
| Hori, H; Kawaguchi, Y; Masubuchi, Y; Ohkura, K; Shinohara, Y; Watanabe, Y | 1 |
1 review(s) available for heme and metyrapone
| Article | Year |
|---|---|
The enzymatic formation of bilirubin.
Topics: Animals; Benzopyrenes; Bile Pigments; Bilirubin; Cytochrome P-450 Enzyme System; Female; Heme; Humans; Macrophages; Methylcholanthrene; Metyrapone; Microsomes; Organ Specificity; Oxidation-Reduction; Oxygenases; Phenobarbital; Placenta; Pregnancy; Proadifen | 1975 |
7 other study(ies) available for heme and metyrapone
| Article | Year |
|---|---|
Studies of the unique nature of the cytochrome P-450 active site. Electron spin resonance spectroscopy as a probe of the hemin iron of cytochrome P-450: the influence of buffer composition, alcohols, and nitrogenous ligands.
Topics: Alkanesulfonates; Animals; Binding Sites; Buffers; Camphor; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Hemin; Male; Membranes; Methanol; Methylcholanthrene; Metyrapone; Microsomes, Liver; Morpholines; Phenobarbital; Pseudomonas; Rats | 1977 |
Effects of griseofulvin on enzymes associated with phase I and II of drug metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Griseofulvin; Heme; Male; Metyrapone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Rats, Inbred Strains | 1986 |
The heme protein P-450 in steroid hydroxylation.
Topics: Adrenal Glands; Animals; Binding Sites; Corticosterone; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fluorides; Heme; Hemoglobins; Horses; Humans; Iron; Metyrapone; Myocardium; NADP; Pregnenolone; Protein Binding; Species Specificity; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Steroid Hydroxylases | 1973 |
Inhibitor/fatty acid interactions with cytochrome P-450 BM3.
Topics: Bacterial Proteins; Circular Dichroism; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Heme; Metyrapone; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Palmitic Acid; Spectrum Analysis; Spectrum Analysis, Raman | 1996 |
Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone.
Topics: Binding Sites; Crystallization; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Metyrapone; Models, Molecular; Phenylalanine; Progesterone; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Water | 2004 |
How do azoles inhibit cytochrome P450 enzymes? A density functional study.
Topics: Azoles; Binding Sites; Camphor; Catalytic Domain; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Kinetics; Liver; Metyrapone; Models, Molecular; Protein Conformation; Water | 2008 |
Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Erythromycin; Heme; Humans; Ketoconazole; Ligands; Metyrapone; Models, Molecular; Molecular Sequence Data; Progesterone; Protein Binding; Protein Conformation; Static Electricity; Substrate Specificity | 2009 |