heme has been researched along with losartan potassium in 218 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 180 (82.57) | 18.7374 |
1990's | 20 (9.17) | 18.2507 |
2000's | 9 (4.13) | 29.6817 |
2010's | 7 (3.21) | 24.3611 |
2020's | 2 (0.92) | 2.80 |
Authors | Studies |
---|---|
Dunn, CD; Napier, JA | 1 |
Bruno, F; Congote, LF; Solomon, S | 1 |
Amaki, I; Horikoshi, A; Miura, Y; Mizoguchi, H; Sasaki, R; Takaku, F | 1 |
De Klerk, G; Goudsmit, R; Hart, AA; Kruiswijk, C | 2 |
Dunn, CR; Napier, JA | 1 |
Bomboy, JD; Graber, SE; Krantz, SB; Salmon, WD | 1 |
George, WJ; Rodgers, GM; White, LA | 1 |
gardner, FH; Gorshein, D; Reisner, EH | 1 |
Eisen, H | 1 |
De Klerk, G; Goudsmit, R; Von dem Borne, AE | 1 |
Gidari, AS; Levere, RD; Stathakis, NE | 1 |
Meints, RH; Mesner, K; Porter, PN | 1 |
de Both, NJ; Klootwijk-van-Dijke, E; Mol, JN; Stoof, TJ; van Griensven, LJ; van't Hull, E; Vermey, M | 1 |
Dunn, CD; Ford, TW; Napier, JA; Price, VA | 2 |
Congote, LF | 1 |
Kurnick, JE; Vautrin, R; Wallner, SF; Ward, HP | 1 |
Barcos, M | 1 |
Agam, G; Djaldetti, M | 1 |
Beaufait, DW; Rosse, C | 1 |
May, A; Napier, JA | 1 |
de Goeij, AF; Dubbelman, TM; Van Steveninck, J | 1 |
Dukes, PP; Hammond, D; Ortega, JA; Shore, NA | 2 |
Congote, LF; Solomon, S | 1 |
Cole, RJ; Regan, T | 1 |
Dargon, PA; Fisher, JW; Gross, DM; Przala, F | 1 |
Di Stefano, J; Lysik, RM; Zucker, S | 1 |
Kataoka, J; Miura, Y; Mizoguchi, H; Shiokawa, Y; Takaku, F | 1 |
Ibayashi, H; Kozuru, M; Nakashima, K | 1 |
Dukes, PP; Fine, RN; Ma, A; Malekzadeh, MH; Ortega, JA; Pennisi, AJ; Shore, N | 1 |
Lysik, RM; Mohammad, G; Zucker, S | 1 |
Blajchman, MA; Browman, GP; Freedman, MH; McBride, JA | 1 |
Carrez, D; Gallien-Lartigue, O | 1 |
Labedzki, L; Reissmann, KR; Udupa, KB | 1 |
Chiba, S; Kosaka, K; Takaku, F; Urabe, A | 1 |
Forget, BG; Glass, J; Housman, D | 1 |
Drivit, W; Geller, G; Zalusky, R; Zanjani, ED | 1 |
Chui, DH; Loyer, BV | 1 |
Bollum, FJ; Hutton, JJ; Roodman, GD | 1 |
Fisher, JW; Moriyama, Y; Rege, A | 1 |
Dunn, CD; Greenman, JM; Jarvis, JH | 1 |
Alfrey, AC; Mishell, J; Vautrin, R; Wallner, SF; Ward, HP | 1 |
Hankins, WD; Krantz, SB | 1 |
Glass, J; Lavidor, LM; Robinson, SH | 1 |
Guiliani, D; Minak, V; Morse, BS; Nussbaum, M | 1 |
Cheek, EM; Cole, RJ; Regan, T; White, SL | 2 |
Zanjani, ED | 1 |
Kuratowska, Z | 1 |
Friedman, S; Lysik, RM; Zucker, S | 2 |
Datta, MC; Dukes, PP | 1 |
Bishop, TR; Boyer, SH; Frelin, LP; Hobbs, S; Noyes, AN; Rogers, OC | 1 |
Cook, JD; Skikne, BS | 1 |
Kauma, H; Timonen, TT | 1 |
Tenhunen, R | 1 |
Beru, N; Goldwasser, E | 2 |
Haines, KM; Nicolaides, NC; Stoeckert, CJ | 1 |
Abraham, NG; Ahmed, T; Konwalinka, G; Levere, RD; Nelson, JC | 1 |
Goldwasser, E | 3 |
Andes, WA; Beltran, G; Makris, CM; Stuckey, WJ | 1 |
Chhabra, R; Datta, K; Singh, NK | 1 |
Monette, FC; Sigounas, G | 2 |
Billat, C; Felix, JM; Jacquot, R; Mayeux, P | 1 |
Chalevelakis, G; Dolkas, G; Lyberatos, C; Pallikaris, G; Raptis, S; Thalassinos, N; Yalouris, AG | 1 |
Arnstein, HR; Bonanou-Tzedaki, SA; Setchenska, MS | 1 |
Dulaney, JT; Hatch, FE; Young, J | 1 |
Chui, LC; Gabuzda, TG; Lewis, HB; Silver, RK | 1 |
Krantz, SB | 6 |
Krantz, SB; Moore, WH; Zaentz, SD | 1 |
Gardner, FH; Gorshein, D | 1 |
Bulat, P; Chung, SK; Menninger, FF; Molinari, PF; Snyder, LM | 1 |
Hotta, T; Yamada, H | 1 |
Conkie, D; Drewienkiewicz, CE; Lanyon, WG; Nicol, AG; Paul, J; Williamson, R | 1 |
Conkie, D; Paul, J | 1 |
Preisler, HD; Zanjani, ED | 1 |
Bottomley, SS; Moore, MA; Smithee, GA; Whitcomb, WH | 1 |
Carrillo, M; Graber, SE; Krantz, SB | 2 |
Jepson, JH; Vas, M | 1 |
Chiba, S; Kosaka, K; Miura, Y; Mori, M; Suzuki, S | 1 |
Adamson, JW; Dale, DC; Elin, RJ | 1 |
Briggs, DW; Fisher, JW; George, WJ | 1 |
Gordon, AS; Rakowitz, F; Van Zant, G; Zucali, JR | 1 |
Clissold, PM | 1 |
Fisher, JW; Lertora, JJ; Moriyama, Y; Rege, AB; Tornyos, K | 1 |
Cheek, EM; Cole, RJ; Tarbutt, RG; White, SL | 1 |
Howe, DM; Weintraub, LR; Zucker, S | 1 |
Burlington, H; Cronkite, EP; Reincke, U; Zanjani, ED | 1 |
Chiyoda, S; Miura, Y; Mizoguchi, H; Suzuki, S; Takaku, F | 1 |
Giladi, M; Preisler, HD | 1 |
Gidari, AS; Ross, J; Zalusky, R; Zanjani, ED | 1 |
Jurd, RD; Maclean, N | 1 |
Jepson, JH | 1 |
Forth, W; Rummel, W | 1 |
Gardner, FH; Gorshein, D; Hait, WM; Jepson, JH | 1 |
Boguslawska-Jaworska, J | 1 |
Halvorsen, S | 1 |
Axelrad, AA; McLeod, DL; Stephenson, JR | 1 |
Necheles, TF | 1 |
Malpas, JS; Wardle, DF; Wrigley, PF | 1 |
Miura, Y; Mizoguchi, H; Suzuki, TS; Takaku, F | 1 |
Fisher, JW; Lertora, JL; Lindholm, DD; Moriyama, Y; Tornyos, K | 1 |
Bartley, ET; Powsner, ER | 1 |
Giuliani, D; Giuliani, ER; Keyhani, M; Morse, BS | 1 |
Cohen, MH; Gidari, AS; Levere, RD | 1 |
Bernstein, SE; Bulat, P; Molinari, PF; Snyder, LM | 1 |
Kao, V; Krantz, SB | 1 |
Miura, Y; Mizoguchi, H; Nakao, K; Takaku, F | 2 |
Ginsberg, M; Josephson, AS; Levere, RD; Lowenthal, I; Swerdlow, F | 1 |
Germano, GJ; Giuliani, DG; Morse, BS | 1 |
Bateman, AE; Cole, RJ; Regan, T; Tarbutt, RG | 1 |
Izak, G; Karsai, A | 1 |
Conkie, D; Freshney, RI; Paul, J | 1 |
Shinton, NK | 1 |
Levere, RD; Mizoguchi, H | 2 |
Bateman, AE; Cole, RJ | 1 |
Chiba, S; Miura, Y; Mizoguchi, H; Nakao, K; Sassa, S; Takaku, M | 1 |
Nakao, K; Sassa, S; Takaku, F; Wada, O | 1 |
Mazur, A | 1 |
Tambourin, P; Wendling, F | 1 |
Goldwasser, E; Hrinda, ME | 1 |
Dukes, PP; Ortega, JA | 1 |
Gordon, AS | 1 |
Bruce, WR; McCool, D; Miller, RJ; Painter, RH | 1 |
Axelrad, AA; Stephenson, JR | 2 |
Okamura, H; Reissmann, KR; Udupa, KB | 1 |
Dukes, PP; Hammond, D | 1 |
Ozawa, S | 1 |
Brown, JR; Cochrane, CE; Cooper, JA | 1 |
Cole, RJ; Hunter, J; Paul, J | 1 |
Fried, W; Kilbridge, T; Krantz, S; Lange, RD; McDonald, TP | 1 |
Bottomley, SS; Smithee, GA | 1 |
Fujioka, S; Nakao, K; Sassa, S; Takaku, F | 1 |
Miura, Y; Nakao, K; Takaku, F | 2 |
Cole, RJ; Paul, J | 1 |
Baglioni, C | 1 |
Danieli, G; Montroni, M | 1 |
Sasa, S | 1 |
Nakao, K | 1 |
Ward, HP | 1 |
Berman, L; Powsner, ER | 1 |
Berman, L; Powsner, E | 1 |
Penington, DG | 1 |
George, WJ; White, LE | 1 |
Beru, N; Goldwasser, E; Sahr, K | 1 |
Fisher, JW; George, WJ; White, L | 1 |
Bondurant, MC; Koury, MJ; Sawyer, ST | 1 |
Broxmeyer, HE; Lu, L | 1 |
Barbieri, R; Bernardi, F; Buzzoni, D; Conconi, F; Del Senno, L; Gambari, R; Marchetti, G; Perrotta, CM; Piva, MR | 1 |
Lipschitz, DA; Udupa, KB | 2 |
Dunn, CD; Trent, D | 1 |
Bondurant, MC; Duncan, DT; Hankins, WD; Koury, MJ; Krantz, SB | 1 |
Fisher, JW | 1 |
Hara, H; Kanamaru, A; Nagai, K; Okamoto, T | 1 |
Cavill, I; Jacobs, A; Kaaba, S; May, A; Smith, S; Ting, WC; Whittaker, JA | 1 |
Barnes, K; de Souza, P; Jacobs, A; Kaaba, S; May, A | 1 |
Takaku, F; Wakabayashi, Y | 1 |
Reissmann, KR; Udupa, KB | 1 |
Kataoka, J; Shiokawa, Y; Sugimoto, M; Takaku, F; Wakabayashi, Y | 1 |
Dunn, CD | 1 |
Eaves, AC; Eaves, CJ; Krystal, G | 2 |
Brandan, NC; Cotes, PM; Espada, J | 1 |
Bondurant, MC; Krantz, SB; Muta, K; Wickrema, A | 1 |
Busfield, SJ; Callus, BA; Chappell, DS; Jennings, G; Klinken, SP; Riches, KJ; Tilbrook, PA; Trengove, NJ | 1 |
Fibach, E; Gelvan, D; Konijn, AM; Meyron-Holtz, EG | 1 |
Abraham, NG; Lutton, JD | 1 |
Krantz, SB; Muta, K | 1 |
Laitinen, E; Pettersson, T; Rosenlöf, K; Tenhunen, R | 1 |
Abraham, NG; Chertkov, JL; Harrison, J; Jiang, S; Kappas, A; Levere, RD; Lutton, JD | 1 |
Goldberg, MA; Schneider, TJ | 1 |
Abraham, NG; Griffin, MO; Kappas, A; Levere, RD; Lutton, JD; Nishimura, M; Shibahara, S | 1 |
de Rooij, FW; Edixhoven-Bosdijk, A; Siersema, PD; Weimar, W; Wilson, JH | 1 |
Irino, S; Kawanishi, K; Kubota, Y; Ohnishi, H; Takahara, J; Tanaka, T; Yamaguchi, M; Yamaoka, G | 1 |
Barrientos, A; Coronel, F; Enríquez de Salamanca, R; Fontanellas, A; Herrero, JA; Morán, MJ; Santos, JL | 1 |
Kozuru, M; Muta, K; Uike, N | 1 |
Arany, Z; Bunn, HF; Galson, D; Ho, V; Huang, LE; Krainc, D; Livingston, DM; Tendler, D | 1 |
Ahmad, S; Chen, F; Chen, YH; Feldman, L; Hoffman, R; Namin, F; Platanias, LC; Stock, W; Uddin, S; Wickrema, A; Yi, T | 1 |
Necas, E; Ponka, P; Sulc, K; Sýkora, V; Zivný, JH | 1 |
Franklin Bunn, H; Horiguchi, H | 1 |
Kozinets, GI; Sarycheva, TG | 1 |
Canonne-Hergaux, F; Gros, P; Ponka, P; Zhang, AS | 1 |
Decristoforo, C; Weiss, G; Zoller, H | 1 |
Juul, SE; Strandjord, TP; Woodrum, DE; Zerzan, JC | 1 |
Weiss, G | 1 |
GALLIEN-LARTIGUE, O; GOLDWASSER, E; KRANTZ, SB | 1 |
FUJII, M | 1 |
NAKOA, K; SASSA, S; TAKAKU, F | 1 |
Juul, SE | 1 |
Bondurant, MC; Kopsombut, P; Koury, MJ; Price, JO; Rhodes, MM | 1 |
Kling, PJ; Labbé, RF; Lott, DG; Widness, JA; Zimmerman, MB | 1 |
Asano, H; Deguchi, Y; Inaba, M; Kawamura, S | 1 |
Berkovitch-Luria, G; Malik, Z; Nudelman, A; Rephaeli, A; Rozic, G; Weitman, M; Yakobovitch, S | 1 |
Cazenave, PA; Dalko, E; Das, B; Herbert, F; Nataf, S; Pays, L; Pied, S; Ravindran, B; Sharma, S; Tchitchek, N | 1 |
Philpott, CC; Protchenko, O; Ryu, MS; Shakoury-Elizeh, M; Zhang, D | 1 |
Bauer, DE; Bergonia, H; Cantor, AB; Chung, J; Coon, JJ; Coughlin, EE; Dailey, HA; Dailey, TA; Ghamari, A; Hebert, AS; Kafina, MD; Kaplan, J; Li, L; Lodish, HF; Maeda, M; Maeda, T; Minogue, CE; Orkin, SH; Pagliarini, DJ; Paw, BH; Phillips, JD; Wittig, JG | 1 |
Denton, C; German, K; Grelli, KN; Juul, SE; Lee, G; Vu, PT | 1 |
Ablain, J; Bauer, DE; Burke, MD; Chen, C; Cheung, JTM; Grillo, AS; Kafina, MD; Kaplan, J; King, MJ; Kingsley, PD; Koehler, CM; Li, H; Li, L; Lodish, HF; Orkin, SH; Palis, J; Paw, BH; Phillips, JD; Shi, J; Shrestha, R; Ward, DM; Yien, YY; Zhang, X; Zon, LI | 1 |
Bahr, TM; Comstock, BA; German, KR; Heagerty, PJ; Juul, SE; Mayock, DE; Parikh, P; Whittington, D | 1 |
Abdullah, Y; Adlung, L; Altamura, S; Andrieux, G; Boehm, ME; Boerries, M; Busch, H; Chakraborty, S; Gröne, HJ; Helm, B; Kastl, P; Klingmüller, U; Lehmann, WD; Muckenthaler, MU; Schilling, M; Schwarzmüller, LE; Wagner, MC | 1 |
13 review(s) available for heme and losartan potassium
Article | Year |
---|---|
The control of haemoglobin synthesis.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Enzyme Activation; Erythropoiesis; Erythropoietin; Fetal Hemoglobin; Globins; Glycine; Heme; Hemoglobins; Humans; Hybrid Cells; Iron; Mitochondria; Oxygen Consumption; Porphyrias; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Succinates; Transcription, Genetic | 1972 |
Hypoplastic anemia. Pathophysiology and therapy.
Topics: Anabolic Agents; Androgens; Anemia, Aplastic; Bone Marrow Transplantation; Erythropoiesis; Erythropoietin; Hematopoietic Stem Cells; Heme; Hepatitis; Humans; Iron; Leukemia; Transplantation, Homologous; Tuberculosis, Miliary | 1973 |
Iron absorption.
Topics: Anemia, Hypochromic; Animals; Bile; Chelating Agents; Chemical Phenomena; Chemistry; Diet; Erythropoietin; Gastric Mucosa; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hypoxia; Intestinal Absorption; Intestinal Mucosa; Iron; Iron Isotopes; Kinetics; Models, Biological; Pancreas; Transferrin | 1973 |
Current concepts of the action of androgenic steroids on erythropoiesis.
Topics: Androgen Antagonists; Androgens; Anemia; Animals; Bone Marrow; Child; DNA; Erythropoiesis; Erythropoietin; Female; Hematopoietic Stem Cells; Heme; Humans; Kinetics; Male; Nandrolone; Steroids; Testosterone; Time Factors | 1973 |
Annotation: pure red cell aplasia.
Topics: Adult; Anemia, Aplastic; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Bone Marrow; Bone Marrow Cells; Child, Preschool; Cyclophosphamide; Erythrocytes, Abnormal; Erythropoiesis; Erythropoietin; Heme; Humans; Immunoglobulin G; Infant; Mercaptopurine; Prednisone; Stimulation, Chemical; Thymectomy; Thymoma | 1973 |
[Metabolism of red blood cells. II. Metabolic contribution of red blood cells in oxygen transport (author's transl)].
Topics: Adaptation, Physiological; Blood Preservation; Diphosphoglyceric Acids; Erythrocytes; Erythropoietin; Glycolysis; Heme; Hemoglobins; Humans; Hypoxia; Iron; Oxygen; Oxyhemoglobins; Time Factors | 1974 |
Pure red-cell aplasia.
Topics: Anemia; Anemia, Aplastic; Antibodies, Anti-Idiotypic; Antigen-Antibody Complex; Autoimmune Diseases; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromium Radioisotopes; Complement System Proteins; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Immunoglobulin G; Immunosuppressive Agents; Iron; Iron Radioisotopes; Middle Aged | 1974 |
Editorial: Inhibitors of erythropoiesis.
Topics: Aminolevulinic Acid; Anemia; Animals; Bone Marrow; Bone Marrow Cells; Depression, Chemical; Erythrocytes; Erythropoiesis; Erythropoietin; Estrogens; Feedback; Female; Heme; Hemoglobins; Humans; Hypoxia; Immunoglobulin G; In Vitro Techniques; Infant, Newborn; Iron; Male; Mice; Models, Biological; Nephritis; Polycythemia; Polycythemia Vera; Rats | 1974 |
Biochemical control of erythroid cell development.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Differentiation; Cobalt; Dactinomycin; Erythropoiesis; Erythropoietin; Genes, Regulator; Glucosamine; Glycols; Hematopoietic Stem Cells; Heme; Hemoglobins; In Vitro Techniques; Models, Biological; Pituitary Gland; Rats; Reticulocytes; RNA; Steroids; Thyroid Hormones | 1966 |
Mechanism of the anemia of chronic renal failure.
Topics: Anemia; Animals; Erythrocyte Aging; Erythropoiesis; Erythropoietin; Hematopoietic Stem Cells; Heme; Humans; Kidney; Kidney Failure, Chronic; Methylguanidine; Models, Biological; Rabbits | 1980 |
Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Hypoxia; Cell Line; DNA-Binding Proteins; Erythropoietin; Gene Expression Regulation; Heme; Hepatocyte Nuclear Factor 4; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Macromolecular Substances; Models, Biological; Nuclear Proteins; Oxygen; Phosphoproteins; Protein Conformation; RNA, Messenger; Signal Transduction; Transcription Factors | 1997 |
[Morphofunctional characteristics of erythron (review of the literature)].
Topics: Adult; Anemia; Anemia, Aplastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cytophotometry; DNA; Erythroblasts; Erythrocytes; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Female; Gestational Age; Heme; Hemoglobins; Humans; Infant, Newborn; Iron; Male; Mitosis; Oxidation-Reduction; Polycythemia; Pregnancy; Reticulocytes; RNA | 2001 |
[Iron, infection and anemia--a classical triad].
Topics: Anemia, Hypochromic; Bacterial Infections; Cytokines; Erythroid Precursor Cells; Erythropoietin; Heme; Hemochromatosis; Humans; Immune Tolerance; Immunity, Cellular; Iron; Macrophages; Neoplasms | 2002 |
2 trial(s) available for heme and losartan potassium
Article | Year |
---|---|
Enterally dosed recombinant human erythropoietin does not stimulate erythropoiesis in neonates.
Topics: Administration, Oral; Blood Transfusion; Enteral Nutrition; Enzyme Inhibitors; Erythropoiesis; Erythropoietin; Hematocrit; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Prospective Studies; Protoporphyrins; Recombinant Proteins; Reticulocyte Count; Time Factors | 2003 |
Do Extremely Low Gestational Age Neonates Regulate Iron Absorption via Hepcidin?
Topics: Biomarkers; Creatinine; Erythropoietin; Ferritins; Heme; Hepcidins; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Iron; Protoporphyrins; Retrospective Studies | 2022 |
203 other study(ies) available for heme and losartan potassium
Article | Year |
---|---|
An evaluation of factors affecting the in vitro bioassay for erythropoietin.
Topics: Animals; Biological Assay; Cells, Cultured; Citrates; Culture Media; Erythropoietin; Evaluation Studies as Topic; Fetus; Folic Acid; Heme; Hemoglobins; Hemolysis; Hydrogen-Ion Concentration; In Vitro Techniques; Iron; Liver; Mice; Testosterone; Vitamin B 12 | 1975 |
alpha-Fetoprotein production and erythropoiesis in cell cultures of human fetal liver.
Topics: alpha-Fetoproteins; Cells, Cultured; DNA; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Hemoglobins; Humans; Liver; Pregnancy | 1977 |
Alterations in the response to erythropoietin and RNA-dependent DNA polymerase activity in mouse spleen cells infected with Friend leukemia virus.
Topics: Animals; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Heme; Leukemia, Experimental; Male; Mice; Mice, Inbred C3H; RNA-Directed DNA Polymerase; Spleen; Time Factors; Tumor Virus Infections | 1979 |
A modification of the mouse fetal liver cell assay for ESF in human serum.
Topics: Animals; Biological Assay; Erythropoietin; Heme; Liver; Mice | 1978 |
Erythropoietin bioassays: experimental design and interpretation of results.
Topics: Animals; Biological Assay; Erythropoietin; Heme; Humans; Iron; Mice | 1978 |
Effect of erythropoietin preparations on cyclic AMP and cyclic GMP levels in rat fetal liver cell cultures.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Erythropoietin; Gestational Age; Heme; Liver; Phosphodiesterase Inhibitors; Rats; Xanthines | 1977 |
Cyclic nucleotides as regulators of erythrocyte proliferation.
Topics: Adenylyl Cyclases; Animals; Cell Division; Cyclic AMP; DNA; Erythrocytes; Erythropoietin; Female; Heme; Kidney; Lactates; Liver; Male; Mice; Mice, Inbred Strains; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Protein Kinases; Rats | 1978 |
Tissue culture of bone marrow. V. Effect of 5Beta(H) steroids and cyclic AMP on heme synthesis.
Topics: Androstanes; Bone Marrow; Bucladesine; Calcium; Cobalt; Culture Techniques; Cyclic AMP; Cyproterone; Drug Synergism; Erythropoiesis; Erythropoietin; Heme; Humans; Hydroxysteroids; Immune Sera; Ketosteroids; Pregnanediones; Pregnanes; Pregnanolone; Stimulation, Chemical; Theophylline | 1975 |
Terminal erythroid differentiation in normal and leukemic mouse cells.
Topics: Analysis of Variance; Animals; Cell Differentiation; Chromatin; Dimethyl Sulfoxide; Erythrocytes; Erythropoietin; Friend murine leukemia virus; Genes; Heme; Leukemia, Erythroblastic, Acute; Liver; Mice; Mice, Inbred DBA; Spectrin | 1978 |
The nature of toxicity of human serum in the bioassay for erythropoietin using mouse foetal liver cells.
Topics: Agglutination Tests; Animals; Antibodies; Biological Assay; Blood; Complement System Proteins; Erythropoietin; Fluorescent Antibody Technique; Heme; Hemolysis; Hot Temperature; Humans; Immunoglobulin Fragments; Immunoglobulin G; Immunoglobulin M; Liver; Mice | 1978 |
Refractory anemia with hyperplastic bone marrow: subclassification based on responsiveness to erythropoietin in vitro.
Topics: Aged; Anemia, Aplastic; Anemia, Sideroblastic; Cells, Cultured; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Male; Middle Aged | 1977 |
Enhancement of erythroid colony growth in culture by hemin.
Topics: Animals; Bone Marrow Cells; Cell Division; Cells, Cultured; Clone Cells; Erythropoiesis; Erythropoietin; Female; Heme; Hemin; Hemoglobins; Hypoxia; Iron Radioisotopes; Mice | 1979 |
A new erythroid cell line induced by Rauscher murine leukaemia virus.
Topics: Animals; Cell Line; Dimethyl Sulfoxide; Erythropoiesis; Erythropoietin; Heme; Hemoglobins; Leukemia, Experimental; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Rauscher Virus | 1978 |
Oxymetholone and erythropoiesis: failure to detect an effect in fetal mouse liver cell cultures.
Topics: Animals; Cells, Cultured; DNA; Erythropoiesis; Erythropoietin; Heme; Hydroxyurea; Liver; Mice; Oxymetholone | 1977 |
Regulation of fetal liver erythropoiesis.
Topics: Cells, Cultured; Erythropoiesis; Erythropoietin; Female; Fetal Hemoglobin; Fetus; Heme; Hemoglobins; Humans; Kidney; Liver; Pregnancy; RNA; Testosterone | 1977 |
The effect of serum from uremic patients on erythropoietin.
Topics: Aged; Animals; Bone Marrow Cells; Dogs; Dose-Response Relationship, Drug; Erythropoiesis; Erythropoietin; Heme; Humans; Hypoxia; Kidney Failure, Chronic; Mice; Middle Aged; Time Factors | 1977 |
Identification by irradiation, in vitro, of two components of erythropoietin action.
Topics: Bone Marrow; Cells, Cultured; Erythropoiesis; Erythropoietin; Gamma Rays; Heme; Iron; Polycythemia Vera; Time Factors; X-Rays | 1978 |
Hormone-stimulated heme synthesis by isolated mitochondria.
Topics: Aging; Animals; Butanones; Erythropoietin; Heme; Insulin; Mice; Mitochondria, Liver; Prostaglandins A; Prostaglandins E | 1978 |
Progenitor cells of erythroblasts: an in vitro investigation of erythropoietin-responsive cells of guinea pig bone marrow.
Topics: Animals; Erythroblasts; Erythropoietin; Guinea Pigs; Hematopoietic Stem Cells; Heme; Male; Polycythemia | 1978 |
Modified method of erythropoietin (ESF) bioassay in vitro using mouse fetal liver cells. I. Effect of serum iron on 59Fe incorporation into heme.
Topics: Dose-Response Relationship, Drug; Erythropoietin; Heme; Iron | 1978 |
Serum iron and the mouse fetal liver cell assay for serum erythropoietin.
Topics: Biological Assay; Cells, Cultured; Erythropoietin; Heme; Humans; Iron; Transferrin | 1978 |
Biochemical studies on erythropoietic protoporphyria.
Topics: Erythrocytes; Erythropoietin; Heme; Humans; Light; Porphyrias; Porphyrins; Protoporphyrins | 1978 |
Congenital hypoplastic anemia inhibition of erythropoiesis by sera from patients with congenital hypoplastic anemia.
Topics: Anemia; Bone Marrow; Cells, Cultured; Erythropoiesis; Erythropoietin; Hematopoietic Stem Cells; Heme; Humans | 1975 |
Isoproterenol stimulation of heme synthesis in cultures of human fetal liver from early gestation.
Topics: Culture Techniques; Erythropoietin; Female; Gestational Age; Heme; Hemoglobins; Humans; Isoproterenol; Liver; Pregnancy; Testosterone | 1977 |
Regulation of pre-natal haemopoiesis: evidence for negative feedback control of erythropoiesis in the foetal mouse.
Topics: Animals; Cell Differentiation; Cells, Cultured; DNA; Erythroblasts; Erythrocytes; Erythropoiesis; Erythropoietin; Fetus; Heme; Kinetics; Liver; Mice; RNA | 1977 |
Effects of in vitro beta-adrenergic activation on rabbit bone marrow erythroid colony forming cells.
Topics: Cells, Cultured; Erythropoiesis; Erythropoietin; Hematopoietic Stem Cells; Heme; Propranolol; Terbutaline | 1977 |
Pathogenesis of anemia in rats with Walker 256 carcinosarcoma.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Carcinoma 256, Walker; Cells, Cultured; Erythropoietin; Heme; Male; Rats; Splenectomy | 1977 |
[Effect of erythropoietin on human cord blood in vitro (author's transl)].
Topics: Erythropoietin; Fetal Blood; Fetal Hemoglobin; Heme; Hemoglobin A; Hemoglobins; Humans; In Vitro Techniques | 1977 |
The influence of alpha thioglycerol on erythropoiesis in fetal mouse liver cell cultures.
Topics: Animals; Cells, Cultured; DNA; Erythropoiesis; Erythropoietin; Glycerol; Heme; Hydroxyurea; In Vitro Techniques; Liver; Mice; Sulfhydryl Compounds | 1977 |
Specific precipitating antibody to human urinary erythropoietin.
Topics: Animals; Antibodies; Bone Marrow; Bone Marrow Cells; Erythropoietin; Heme; Humans; Immunoelectrophoresis; Precipitin Tests; Rabbits | 1976 |
Effect of residual kidney function on in vitro marrow erythropoiesis in chronic renal failure.
Topics: ABO Blood-Group System; Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Erythropoiesis; Erythropoietin; Heme; Humans; Kidney; Kidney Failure, Chronic; Prostaglandins E; Renal Dialysis; Stimulation, Chemical | 1976 |
Erythropoiesis in chronic renal disease.
Topics: Adult; Anemia; Anemia, Hypochromic; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoiesis; Erythropoietin; Heme; Humans; Kidney Failure, Chronic; Male | 1976 |
A complement independent erythropoietic inhibitor acting on the progenitor cell in refractory anemia.
Topics: ABO Blood-Group System; Anemia, Aplastic; Cells, Cultured; Complement System Proteins; Depression, Chemical; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Immunoglobulin G; Middle Aged | 1976 |
Sensitivity of 15-day mouse fetal liver cells to erythropoietin (ESF). Its practical application to in vitro methods of ESF bioassay.
Topics: Animals; Biological Assay; Cells, Cultured; Dose-Response Relationship, Drug; Erythroblasts; Erythropoietin; Female; Fetus; Gestational Age; Heme; Iron; Liver; Mice; Mice, Inbred C3H; Pregnancy | 1976 |
Induction of erythroid colony forming cells (CFU-E) in murine spleen by endotoxin.
Topics: Animals; Endotoxins; Erythropoiesis; Erythropoietin; Female; Heme; Mice; Polycythemia; Salmonella typhi; Spleen | 1976 |
Response of uraemic bone marrow cells to erythropoietin in vitro.
Topics: Adolescent; Adult; Anemia, Hypochromic; Bone Marrow; Bone Marrow Cells; Dose-Response Relationship, Drug; Erythropoietin; Female; Hematopoiesis; Heme; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Uremia | 1976 |
Erythroid cell differentiation.
Topics: Anemia, Hemolytic; Animals; Blood Cell Count; Cell Differentiation; Cell Division; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Fetal Hemoglobin; Genes; Globins; Hematopoietic Stem Cells; Heme; Hemoglobin H; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phenylhydrazines; RNA, Messenger; Time Factors | 1976 |
Lack of erythropoietic inhibitory effect of serum from patients withe congenital pure red cell aplasia.
Topics: Anemia, Aplastic; Animals; Antibodies; Blood Proteins; Bone Marrow; Bone Marrow Cells; Erythropoiesis; Erythropoietin; Female; Goats; Heme; Humans; Infant; Iron Radioisotopes; Male; Mice; Neutralization Tests; Rabbits; Rats | 1975 |
Erythropoiesis in steel mutant mice: effects of erythropoietin in vitro.
Topics: Anemia, Macrocytic; Animals; Bone Marrow Cells; Cells, Cultured; Erythropoiesis; Erythropoietin; Femur; Heme; Iron Radioisotopes; Mice; Mutation; Sheep | 1975 |
DNA polymerase activities during erythropoiesis. Effects of erythropietin, vinblastine, colcemid, and daunomycin.
Topics: Animals; Atmospheric Pressure; Centrifugation, Density Gradient; Daunorubicin; Demecolcine; Depression, Chemical; DNA; DNA Nucleotidyltransferases; Erythropoiesis; Erythropoietin; Female; Heme; Iron Radioisotopes; Mice; Spleen; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Vinblastine | 1975 |
Studies on an inhibitor of erythropoiesis. II. Inhibitory effects of serum from uremic rabbits on heme synthesis in rabbit bone marrow cultures (38483).
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoiesis; Erythropoietin; Hematocrit; Heme; Iron; Nephrectomy; Rabbits; Uremia | 1975 |
A quantitative bioassay for erythropoietin using mouse fetal liver cells.
Topics: Animals; Biological Assay; Butanones; Culture Media; Cyclohexanones; Erythropoietin; Ferric Compounds; Fetus; Gestational Age; Heme; Liver; Mice; Time Factors | 1975 |
The anemia of chronic renal failure: in vitro response of bone marrow to erythropoietin.
Topics: Adult; Anemia; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoietin; Hematocrit; Heme; Humans; Iron; Kidney Failure, Chronic; Middle Aged; Uremia | 1975 |
In vitro expression of erythroid differentiation induced by Friend polycythaemia virus.
Topics: Animals; Cell Differentiation; Cells, Cultured; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Heme; Iron; Iron Radioisotopes; Kinetics; Mice; Mice, Inbred BALB C; Polycythemia; Spleen | 1975 |
Studies of murine erythroid cell development. Synthesis of heme and hemoglobin.
Topics: 5-Aminolevulinate Synthetase; Animals; Carbon Radioisotopes; Cell Differentiation; Cell Separation; Cells, Cultured; Centrifugation, Density Gradient; Erythroblasts; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Hemoglobins; Iron Radioisotopes; Mice; Spleen; Tritium | 1975 |
Abnormal erythroid maturation in mice induced by isoniazid.
Topics: Anemia, Sideroblastic; Animals; Blood Cell Count; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Injections, Intradermal; Injections, Intravenous; Isoniazid; Mice; Reticulocytes | 1975 |
Expression of congenital defects in the haemopoietic micro-environment. Erythroid and granulocyte-macrophage progenitor cells in pre-natal 'steel' (Slj/Slj) anaemic mice.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Clone Cells; Erythroblasts; Erythropoiesis; Erythropoietin; Genotype; Granulocytes; Hematopoiesis; Heme; Leukocytes; Liver; Macrophages; Mice; Mutation; Spleen | 1975 |
The relationship between erythropoietin-dependent cellular differentiation and colony-forming ability in prenatal haemopoietic tissues.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Erythroblasts; Erythrocytes; Erythropoietin; Granulocytes; Hematopoiesis; Heme; Liver; Macrophages; Mice; Spleen | 1975 |
Haem synthesis in the Diamond-Blackfan syndrome.
Topics: Anemia, Aplastic; Bone Marrow; Child, Preschool; Dose-Response Relationship, Drug; Erythrocytes, Abnormal; Erythropoietin; Female; Heme; Humans; Male; Syndrome | 1975 |
Hematopoietic factors in polycythemia vera.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoietin; Female; Hematocrit; Hematopoiesis; Heme; Humans; Hypoxia; Male; Mice; Polycythemia Vera | 1976 |
[Androgens and erytropoietin in the regulation hematopoiesis].
Topics: Adenylyl Cyclases; Androgens; Anemia, Aplastic; Erythropoiesis; Erythropoietin; Heme; Humans; Kidney; RNA; Testosterone | 1976 |
Diminished bone marrow responsiveness to erythropoietin in myelophthisic anemia.
Topics: Adult; Aged; Anemia, Myelophthisic; Animals; Bone Marrow; Bone Marrow Cells; Erythropoiesis; Erythropoietin; Heme; Humans; In Vitro Techniques; Iron; Male; Middle Aged | 1976 |
Erythropoietin action in rat marrow cell cultures in complete absence of dna synthesis. II. Long term effects on macromolecular synthesis.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; DNA Replication; Erythropoietin; Glycoproteins; Heme; Iridium; Protein Biosynthesis; Rats; RNA; Transcription, Genetic; Uridine | 1976 |
Roles of erythropoietin, insulin-like growth factor 1, and unidentified serum factors in promoting maturation of purified murine erythroid colony-forming units.
Topics: Animals; Blood; Cell Count; Cell Division; DNA; Erythroid Precursor Cells; Erythropoietin; Growth Substances; Heme; Humans; Insulin-Like Growth Factor I; Mice; Recombinant Proteins | 1992 |
Effect of enhanced erythropoiesis on iron absorption.
Topics: Adult; Erythropoiesis; Erythropoietin; Female; Ferritins; Ferrous Compounds; Food; Heme; Humans; Intestinal Absorption; Iron; Iron Radioisotopes; Male; Recombinant Proteins; Transferrin | 1992 |
Therapeutic effect of heme arginate in myelodysplastic syndromes.
Topics: Adult; Aged; Alanine Transaminase; Arginine; Aspartate Aminotransferases; Bone Marrow; Creatinine; Erythropoietin; Female; Heme; Humans; Karyotyping; Male; Middle Aged; Myelodysplastic Syndromes | 1992 |
Erythropoietin in the regulation of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Animals; Erythropoiesis; Erythropoietin; Ferrochelatase; Heme; Humans; Porphobilinogen Synthase | 1990 |
Studies of the effect of erythropoietin on heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Cell Hypoxia; Cells, Cultured; Enzyme Induction; Erythroid Precursor Cells; Erythropoietin; Ferrochelatase; Gene Expression Regulation; Heme; Hemoglobins; Hydroxymethylbilane Synthase; Hyperplasia; Polycythemia; Rats; Stimulation, Chemical; Transaminases | 1989 |
Cytosine arabinoside plus hemin treatment of a human erythroid cell line, KMOE, strongly induces embryonic, fetal, and adult beta-like globin genes.
Topics: Aminolevulinic Acid; Cytarabine; Dimethyl Sulfoxide; Drug Synergism; Erythroid Precursor Cells; Erythropoietin; Gene Expression Regulation; Globins; Heme; Hemin; Humans; Leukemia, Erythroblastic, Acute; RNA, Messenger; Stimulation, Chemical; Tumor Cells, Cultured | 1989 |
Erythropoietin controls heme metabolic enzymes in normal human bone marrow culture.
Topics: 5-Aminolevulinate Synthetase; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Drug Synergism; Erythrocytes; Erythropoietin; Hematopoietic Stem Cells; Heme; Heme Oxygenase (Decyclizing); Hemin; Heptanoates; Humans; Hydroxymethylbilane Synthase; Osmolar Concentration; Reference Values | 1989 |
The action of erythropoietin as the inducer of erythroid differentiation.
Topics: Cell Differentiation; Erythroblasts; Erythropoiesis; Erythropoietin; Gene Expression Regulation; Glycophorins; Glycoside Hydrolases; Hematopoietic Stem Cells; Heme; Hemoglobins; Humans; Radioimmunoassay; Receptors, Cell Surface; Receptors, Erythropoietin; Structure-Activity Relationship | 1985 |
Hemoglobin production in human bone marrow cultures is inhibited by lyophilized coagulation factor concentrates.
Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoietin; Factor IX; Factor VIII; Fibrinogen; Freeze Drying; Growth Inhibitors; Hematopoietic Stem Cells; Heme; Hemoglobins; Humans | 1986 |
Induction of L-alanine:4,5-dioxovalerate transaminase by phenylhydrazine is associated with depletion of heme level.
Topics: Anemia; Animals; Cobalt; Dactinomycin; Erythropoietin; Hematocrit; Heme; Immune Sera; Immunodiffusion; Kidney; Kinetics; Liver; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Transaminases | 1986 |
Growth of murine multipotent stem cells in a simple "serum-free" culture system: role of interleukin-3, erythropoietin, and hemin.
Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Colony-Forming Units Assay; Culture Media; Dose-Response Relationship, Drug; Erythropoietin; Female; Hematopoiesis; Hematopoietic Stem Cells; Heme; Hemin; Interleukin-3; Mice; Mice, Inbred Strains | 1988 |
Sensitivity of murine multipotential stem cell colony (CFU-GEMM) growth to interleukin-3, erythropoietin, and hemin.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Erythropoietin; Female; Hematopoietic Stem Cells; Heme; Hemin; Interleukin-3; Mice | 1987 |
Induction by hemin of proliferation and of differentiation of progenitor erythroid cells responsible for erythropoietin.
Topics: Animals; Cell Differentiation; Cell Division; Erythrocyte Membrane; Erythropoietin; Female; Globins; Heme; Hemin; Immune Sera; Kinetics; Liver; Pregnancy; Rats; RNA, Messenger; Stem Cells | 1986 |
Effect of uremic plasma on mouse liver delta-aminolevulinic acid synthetase activity.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Animals; Erythropoietin; Female; Heme; Humans; In Vitro Techniques; Liver; Male; Mice; Middle Aged; Uremia | 1986 |
Stimulation of the adenylate cyclase activity of rabbit bone marrow immature erythroblasts by erythropoietin and haemin.
Topics: Adenylyl Cyclases; Animals; Bone Marrow; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Erythroblasts; Erythropoietin; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heme; Hemin; Isoproterenol; Rabbits; Thionucleotides | 1986 |
Effect of amines on erythropoietin-stimulated heme synthesis in fetal mouse liver cells.
Topics: Amines; Animals; Cell Survival; Diamines; Erythropoietin; Fetus; Heme; In Vitro Techniques; Iron Radioisotopes; L-Lactate Dehydrogenase; Liver; Mice; Molecular Weight; Polyamines; Spermine; Structure-Activity Relationship | 1985 |
The regulation of heme biosynthesis during erythropoietin-induced erythroid differentiation.
Topics: 5-Aminolevulinate Synthetase; Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Erythropoietin; Ferrochelatase; Heme; Hydroxymethylbilane Synthase; Iron; Kinetics; Male; Mitochondria; Porphobilinogen Synthase; Rats; Transaminases | 1985 |
The formation of foetal and adult haemoglobin in cell cultures of neonatal calf marrow.
Topics: Animals; Animals, Newborn; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cattle; Culture Techniques; Erythropoietin; Fetal Hemoglobin; gamma-Globulins; Heme; Hemoglobins; Iron; Iron Isotopes; Isoleucine; Leucine; Stimulation, Chemical | 1970 |
Studies on red cell aplasia. 3. Treatment with horse antihuman thymocyte gamma globulin.
Topics: Anemia, Aplastic; Animals; Antibodies; Antilymphocyte Serum; Bone Marrow Cells; Cells, Cultured; Chromatography, DEAE-Cellulose; Cyclophosphamide; Cytotoxicity Tests, Immunologic; Erythropoiesis; Erythropoietin; Female; Fluorescent Antibody Technique; gamma-Globulins; Heme; Horses; Humans; Immunoelectrophoresis; Immunoglobulin G; Immunosuppression Therapy; Iron Isotopes; Leukocyte Count; Middle Aged; Sheep; Thymus Gland; Ultracentrifugation | 1972 |
Studies on red cell aplasia. V. Presence of erythroblast cytotoxicity in G-globulin fraction of plasma.
Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Erythrocytes, Abnormal; Erythropoietin; gamma-Globulins; Heme; Hemoglobins; Humans; Iron Isotopes; Male; Middle Aged; Prednisone | 1973 |
Regulation of erythropoiesis by androgens.
Topics: Androgens; Anemia; Animals; Bone Marrow; Chick Embryo; Dactinomycin; Erythropoiesis; Erythropoietin; Haplorhini; Heme; Hemoglobins; Humans; Hypoxia; Iron Isotopes; Mice; Oxygen; Stimulation, Chemical; Testosterone; Time Factors | 1973 |
Hemoglobin synthesis inhibiting factor (HSIF). Chemical and biological characterizations.
Topics: Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Butanones; Chromatography, Gel; Depression, Chemical; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Female; Heme; Hemoglobins; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Iron; Iron Radioisotopes; Lipoproteins; Rats; Rats, Inbred Strains; Reticulocytes | 1974 |
In vitro response of bone marrow cells to erythropoietin in aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythrocytes, Abnormal; Erythropoietin; Female; Heme; Humans; Iron; Iron Radioisotopes; Male; Middle Aged; Stimulation, Chemical | 1974 |
Characteristics of erythropoietin-induced RNA from foetal mouse liver erythropoietic cell cultures and the effects of 5-fluorodeoxyuridine.
Topics: Animals; Autoradiography; Cells, Cultured; Chemical Phenomena; Chemistry; DNA; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Female; Fetus; Floxuridine; Heme; Iron Isotopes; Kinetics; Liver; Mice; Phosphorus Isotopes; Pregnancy; RNA; RNA, Ribosomal; Tritium; Uridine | 1972 |
Effects of inhibitors of DNA synthesis on the stimulation of mouse erythroid cells by erythropoietin.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; DNA; Erythrocytes; Erythropoietin; Fetus; Floxuridine; Hematopoietic Stem Cells; Heme; Hemoglobins; Hydroxyurea; Iron Isotopes; Liver; Mice; Phosphorus Isotopes; RNA; Stimulation, Chemical; Tritium | 1973 |
Erythropoietin-induced stimulation of heme synthesis by dimethylsulfoxide-treated Friend leukemic cells in vitro.
Topics: Animals; Dimethyl Sulfoxide; Erythropoietin; Heme; Kinetics; Leukemia, Experimental; Mice; Tumor Cells, Cultured | 1974 |
Effect of cyclic adenosine-3',5'-monophosphate on bone marrow delta-aminolevulinic acid synthetase and erythrocyte iron uptake.
Topics: Acyltransferases; Adenine Nucleotides; Amino Acids; Animals; Bone Marrow; Bone Marrow Cells; Culture Techniques; Cyclic AMP; Cycloheximide; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Iron; Iron Isotopes; Levulinic Acids; Mice; Mitochondria; Rabbits; Stimulation, Chemical; Succinates; Theophylline | 1971 |
The effect of cyclic AMP on heme synthesis by rat bone marrow cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone Marrow; Bone Marrow Cells; Butyrates; Cells, Cultured; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dose-Response Relationship, Drug; Epinephrine; Erythropoietin; Heme; Imidazoles; In Vitro Techniques; Insulin; Iron; Iron Isotopes; Male; Rats; Stimulation, Chemical; Transferrin; Xanthines | 1972 |
Lack of effect of erythropoietin on cyclic adenosine-3',5'-monophosphate levels in rat fetal liver cells.
Topics: Animals; Cyclic AMP; Epinephrine; Erythropoietin; Female; Heme; Iron; Iron Radioisotopes; Liver; Pregnancy; Rats; Theophylline; Time Factors | 1974 |
Decreased in vivo and in vitro erythropoiesis induced by plasma of ten patients with thymoma, lymphosarcoma, or idiopathic erythroblastopenia.
Topics: Anemia; Bone Marrow; DNA; Erythropoiesis; Erythropoietin; Heme; Humans; Immunoglobulin G; In Vitro Techniques; Iron Radioisotopes; Lymphoma, Non-Hodgkin; Male; RNA; Thymidine; Thymoma; Tritium | 1974 |
Effect of methenolone acetate on erythropoietin responsive cells in rat bone marrow.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoiesis; Erythropoietin; Female; Hematocrit; Heme; Iron; Iron Radioisotopes; Methenolone; Polycythemia; Rats; Time Factors | 1974 |
Hematopoiesis in the grey collie dog: studies of the regulation of erythropoiesis.
Topics: Animals; Blood Transfusion; Dogs; Erythrocyte Count; Erythropoiesis; Erythropoietin; Granulocytes; Hematocrit; Heme; Hemoglobins; Hemorrhage; Iron; Iron Radioisotopes; Leukocyte Count; Reticulocytes | 1974 |
Hepatic clearance of intact and desialylated erythropoietin.
Topics: Animals; Binding, Competitive; Biological Assay; Bone Marrow; Erythropoietin; Heme; In Vitro Techniques; Iron; Iron Radioisotopes; Liver; Male; Neuraminidase; Orosomucoid; Perfusion; Rabbits; Rats; Sialic Acids; Time Factors | 1974 |
Separation of erythropoietin-responsive cells (ERC) from rat bone marrow.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Fractionation; Cells, Cultured; Culture Media; Erythrocyte Count; Erythropoietin; Hematopoietic Stem Cells; Heme; Iron Radioisotopes; Lymphocytes; Male; Mesothelin; Rats; Serum Albumin, Bovine; Time Factors | 1974 |
Differentiation studies on separated rabbit early erythroid cells.
Topics: Anemia; Animals; Cell Differentiation; Cell Separation; Cells, Cultured; Centrifugation, Density Gradient; Erythrocytes; Erythropoietin; Hematopoietic Stem Cells; Heme; Hemoglobins; Iron Radioisotopes; Phenylhydrazines; Rabbits; Serum Albumin, Bovine; Time Factors | 1974 |
The role of inhibitors of heme synthesis and bone marrow erythroid colony forming cells in the mechanism of anemia of renal insufficiency.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Humans; Iron; Kidney; Kidney Diseases; Rabbits; Uremia | 1974 |
Expression of congenital defects in the haemopoietic micro-environment: pre-natal erythropoiesis in anaemic 'Steel' (Slj-Slj) mice.
Topics: Anemia; Animals; Autoradiography; Cell Count; Cell Differentiation; Cell Division; Cells, Cultured; Erythrocyte Count; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Fetal Diseases; Heme; Hemoglobins; Liver; Mice; Mutation; Pregnancy; Thymidine; Tritium | 1974 |
Bone marrow response to erythropoietin in polycythemia vera and chronic granulocytic leukemia.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoiesis; Erythropoietin; Female; Hematocrit; Heme; Hemoglobinometry; Humans; Iron; Iron Isotopes; Leukemia, Myeloid; Male; Middle Aged; Polycythemia Vera; Reticulocytes | 1972 |
Erythropoietin production in cultures of goat renal glomeruli.
Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Culture Media; Culture Techniques; Erythrocytes; Erythropoietin; Goats; Heme; Humans; Iron; Kidney Glomerulus; Mice; Neuraminidase; Rats | 1972 |
Effect of erythropoietin on human bone marrow cells in vitro. 3. Studies of acute leukemia.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoietin; Heme; Leukemia, Lymphoid; Leukemia, Myeloid, Acute | 1974 |
Erythropoietin responsiveness of differentiating Friend leukaemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Depression, Chemical; Dimethyl Sulfoxide; DNA, Neoplasm; Erythropoietin; Friend murine leukemia virus; Heme; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Neoplasm Proteins; RNA, Neoplasm; Stimulation, Chemical | 1974 |
Site of action of a serum inhibitor of erythropoiesis.
Topics: Adult; Animals; Antibodies; Antibodies, Antinuclear; Autoimmune Diseases; Binding Sites; Bone Marrow Examination; Erythropoiesis; Erythropoietin; Female; Hematocrit; Heme; Hemoglobinometry; Humans; Immune Sera; Immunoglobulin G; In Vitro Techniques; Iron Isotopes; Leukocyte Count; Mice; Myasthenia Gravis; Purpura, Thrombocytopenic; Rats; Reticulocytes; Rheumatoid Factor | 1973 |
Erythroid nature of the response to Friend leukemia virus infection in mice.
Topics: Animals; Blood Protein Electrophoresis; Cell Count; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Erythropoietin; Friend murine leukemia virus; Heme; Hemoglobins; Iron Isotopes; Leukemia, Experimental; Mice; Polycythemia | 1972 |
Studies on the control of hemoglobin synthesis: a model of erythroid differentiation based upon the in vitro effect of erythropoietin and 5 beta-H steroids.
Topics: Bone Marrow; Bone Marrow Cells; Cell Differentiation; Erythrocytes; Erythropoietin; Etiocholanolone; Globins; Glycine; Heme; Hemoglobins; Humans; Tritium | 1972 |
Bioassay of erythropoietin using foetal mouse liver cells.
Topics: Animals; Biological Assay; Culture Techniques; Dose-Response Relationship, Drug; Erythropoietin; Fetus; Heme; Iron Isotopes; Liver; Methods; Mice | 1973 |
Effect of erythropoietin on the spleen of the polycythemic mouse in vitro. V. Localization of erythropoietin-responsive cells in the spleen.
Topics: Animals; DNA; Erythropoietin; Hematopoiesis; Heme; Hypersplenism; Iron Radioisotopes; Mice; Organ Culture Techniques; Polycythemia; Spleen | 1973 |
Erythropoietin production and inhibitors in serum in the anemia of uremia.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythropoietin; Heme; Humans; Rabbits; Uremia | 1973 |
Erythropoietin in vitro. A culture plate method for marrow.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cattle; Cells, Cultured; Culture Media; Culture Techniques; Erythropoietin; Fetus; Glass; Heme; Iron Radioisotopes; Methods; Polytetrafluoroethylene; Rats; Serum Albumin, Bovine | 1974 |
Bone marrow erythropoiesis in the anemia of infection, inflammation, and malignancy.
Topics: Aged; Anemia; Animals; Arthritis, Rheumatoid; Biological Assay; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Dose-Response Relationship, Drug; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Infections; Iron Radioisotopes; Male; Mice; Middle Aged; Neoplasms; Rats | 1974 |
Erythropoiesis in pyridoxine deficient mice.
Topics: Anemia, Sideroblastic; Animals; Blood Transfusion; Cell Differentiation; Erythrocyte Count; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Hematocrit; Hematopoietic Stem Cells; Heme; Hemoglobinometry; Iron; Iron Radioisotopes; Leukocyte Count; Mice; Pyridoxine; Reticulocytes; Time Factors; Vitamin B 6 Deficiency | 1974 |
Heme synthesis by cultured human marrow cells in response to cyanate-treated erythropoietin.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cells, Cultured; Cyanates; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Heme; Humans | 1974 |
Effect of testosterone propionate on the erythropoietic tissue of three congenital anemias in mice.
Topics: Anemia; Animals; Bone Marrow; Diphosphoglyceric Acids; Erythrocytes; Erythropoietin; Heme; Mice; Propionates; Testosterone | 1974 |
Studies on red cell aplasia. I. Demonstration of a plasma inhibitor to heme synthesis and an antibody to erythroblast nuclei.
Topics: Antibodies; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Culture Techniques; Erythrocytes; Erythroplasia; Erythropoietin; Fluorescent Antibody Technique; Heme; Humans; Male; Mercaptopurine; Middle Aged | 1967 |
Effect of erythropoietin on polycythemic mouse spleen in vitro. IV. Response to the colony-forming cells to erythropoietin.
Topics: Animals; Blood Transfusion; Bone Marrow Transplantation; Culture Techniques; Erythropoiesis; Erythropoietin; Female; Hematopoiesis; Heme; Lymphocytes; Methods; Mice; Polycythemia; Spleen | 1968 |
Porphyrin synthesis by cultured lymphocytes.
Topics: 5-Aminolevulinate Synthetase; Carbon Isotopes; Cells, Cultured; Enzyme Induction; Erythropoietin; Fluorometry; Heme; Humans; Ketosteroids; Lectins; Leucine; Levulinic Acids; Lymphocyte Activation; Lymphocytes; Microscopy, Fluorescence; Porphyrins; Pregnenolone | 1972 |
Abnormal erythroid maturation following acute lead toxicity in mice.
Topics: Animals; Cell Differentiation; Embryo, Mammalian; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Hypoxia; Iron Isotopes; Lead; Lead Poisoning; Mice | 1972 |
The role of erythropoietin in prenatal erythropoiesis of congenitally anaemic flexed-tailed (f-f) mice.
Topics: Anemia; Animals; Body Weight; DNA; Erythropoiesis; Erythropoietin; Fetus; Heme; Hemoglobins; Iron; Liver; Mice; Mice, Inbred Strains; Reticulocytes; RNA; Rodent Diseases; Thymidine | 1972 |
The effect of erythropoietin on synchronized rabbit hemopoietic tissue in culture.
Topics: Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Cell Differentiation; Cell Fractionation; Cells, Cultured; DNA; Electrophoresis, Disc; Erythrocytes; Erythropoietin; Hematopoietic Stem Cells; Heme; Rabbits; RNA; Thymidine; Tritium; Uridine | 1972 |
Effect of erythropoietin on haemoglobin synthesis and haem synthesizing enzymes of mouse foetal liver cells in culture.
Topics: 5-Aminolevulinate Synthetase; Acyltransferases; Amino Acids; Animals; Cells, Cultured; Culture Techniques; Embryo, Mammalian; Enzyme Activation; Enzyme Induction; Erythropoietin; Fetus; Heme; Hemoglobins; Hydro-Lyases; Iron; Iron Isotopes; Levulinic Acids; Liver; Lyases; Mice; Porphyrins; Transferrin | 1972 |
Red cell production.
Topics: Animals; Bone Marrow Diseases; DNA; Erythropoiesis; Erythropoietin; Fetus; Globins; Hematopoietic Stem Cells; Heme; Hemoglobins; Humans; Iron; Mitosis; Models, Biological; Polycythemia; Reticulocytes | 1972 |
Stimulation of alpha and beta polypeptide chain synthesis in cultured human marrow by erythropoietin.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cells, Cultured; Chromatography, Ion Exchange; Erythropoietin; Globins; Heme; Hemoglobins; Humans; Iron; Iron Isotopes; Macromolecular Substances; Peptide Biosynthesis; Peptides; Stimulation, Chemical; Urea; Valine | 1972 |
Enhancement of heme and globin synthesis in cultured human marrow by certain 5 -H steroid metabolites.
Topics: 5-Aminolevulinate Synthetase; Bile Acids and Salts; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cells, Cultured; Chromatography; Dactinomycin; Enzyme Induction; Erythropoiesis; Erythropoietin; Etiocholanolone; Globins; Heme; Hemoglobins; Humans; In Vitro Techniques; Iron; Iron Isotopes; Ketones; Ketosteroids; Methylcellulose; Pregnanediol; Pregnanes; Progesterone; Puromycin; Stimulation, Chemical; Testosterone; Valine | 1971 |
Stimulation of haem synthesis by erythropoietin in mouse yolk-sac-stage embryonic cells.
Topics: Amino Acids; Animals; Embryo, Mammalian; Erythropoiesis; Erythropoietin; Female; Gestational Age; Heme; Iron; Iron Isotopes; Levulinic Acids; Mice; Pregnancy | 1971 |
The effect of erythropoietin on human bone marrow cells in vitro. I. Studies of nine cases of bone marrow failure.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Cells, Cultured; Dose-Response Relationship, Drug; Erythropoietin; Female; Heme; Humans; Kinetics; Male; Middle Aged; Time Factors | 1971 |
Enzymatic studies on erythroid differentiation and proliferation.
Topics: Animals; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Hydro-Lyases; Iron; Iron Isotopes; Ligases; Mice; Spleen | 1968 |
Application of the in vitro erythropoietin system to the study of human bone marrow disease: polycythemia vera.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Culture Techniques; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Male; Polycythemia Vera | 1968 |
Role of the spleen in iron metabolism.
Topics: Animals; Bone Marrow; Carbon Isotopes; Cobalt; Enzymes; Erythrocytes; Erythropoietin; Glycine; Heme; Hemorrhage; Histones; Iron; Iron Isotopes; Liver; Lyases; Lymphoma, Non-Hodgkin; Lysine; Phenylhydrazines; Porphyrins; Radiation Effects; Rats; Reticulocytes; Spleen | 1969 |
Malignant transformation and erythroid differentiation by polycythaemia-inducing Friend virus.
Topics: Animals; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dactinomycin; Erythrocytes, Abnormal; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Heme; Hemoglobins; Iron Isotopes; Mice; Mice, Inbred Strains; Polycythemia; Reticulocytes; Spleen; Virus Replication | 1971 |
On the mechanism of erythropoietin-induced differentiation. VI. Induced accumulation of iron by marrow cells.
Topics: Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Cattle; Cell Differentiation; Chromatography, Gel; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Depression, Chemical; Erythropoiesis; Erythropoietin; Femur; Ferritins; Heme; Iron; Iron Isotopes; Male; Metabolism; Puromycin; Rats; RNA; Sheep; Stimulation, Chemical; Tibia; Time Factors; Transferrin | 1969 |
Relationship between erythropoietin effect and reduced DNA synthesis in marrow cell cultures.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Cytarabine; Depression, Chemical; DNA; Erythropoietin; Glucosamine; Glycine; Heme; Iron; Iron Isotopes; Metabolism; Rats; Sheep; Stimulation, Chemical; Thymidine; Time Factors; Tritium | 1970 |
Erythropoietin: a complex with different in vivo and in vitro activities.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Erythrocytes; Erythropoiesis; Erythropoietin; Glucosamine; Heme; Hypoxia; Iron; Iron Isotopes; Methods; Mice; Polycythemia | 1970 |
Biochemical mechanisms underlying hematopoietic cell differentiation.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Culture Techniques; Erythrocytes; Erythropoiesis; Erythropoietin; Fetus; Germ Layers; Hematopoietic Stem Cells; Hematopoietic System; Heme; Hemoglobins; Iron Isotopes; Kidney; Levulinic Acids; Liver; Mice; Rats; RNA; RNA, Messenger; RNA, Transfer; Spleen; Tritium; Uridine | 1970 |
Erythropoietin sensitivity of rat bone marrow cells separated by velocity sedimentation.
Topics: Animals; Biophysical Phenomena; Biophysics; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Erythrocytes; Erythropoietin; Heme; Iron; Iron Isotopes; Male; Methods; Rats; Time Factors; Vinblastine | 1970 |
Separation of erythropoietin-sensitive cells from hemopoietic spleen colony-forming stem cells of mouse fetal liver by unit gravity sedimentation.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Count; Centrifugation, Density Gradient; Clone Cells; Culture Techniques; Erythropoietin; Fetus; Hematopoiesis; Hematopoietic Stem Cells; Heme; Iron Isotopes; Liver; Mice; Spleen; Transferrin | 1971 |
On the mechanism of erythropoietic action of hemoglobin and its derivatives.
Topics: Animals; Erythrocyte Count; Erythropoiesis; Erythropoietin; Female; Gerbillinae; Heme; Hemoglobins; Hypoxia; Immune Sera; Iron; Iron Isotopes; Mice; Polycythemia; Rats; Reticulocytes; Species Specificity; Stimulation, Chemical | 1971 |
Incomplete erythropoietin activity in normal plasma components.
Topics: Animals; Blood Coagulation Factors; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chemistry Techniques, Analytical; Culture Techniques; Erythrocytes; Erythropoietin; Glucosamine; Heme; Humans; Iron; Iron Isotopes; Methods; Mice; Polycythemia; Rats | 1971 |
Quantitative assay method for erythropoietin in vitro.
Topics: Animals; Biological Assay; Culture Techniques; Erythropoietin; Female; Fetus; Heme; Iron; Iron Isotopes; Liver; Methods; Mice; Pregnancy; Stimulation, Chemical | 1971 |
Erythropoietin from the kidney cells cultured in vitro.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Culture Media; Culture Techniques; Erythropoietin; Heme; Iron Isotopes; Kidney; Rabbits | 1967 |
In vitro effect of erythropoietin on the spleen of the polycythemic mouse. 3. Limited exposure to erythropoietin and actinomycin D.
Topics: Animals; Blood Cell Count; Culture Techniques; Dactinomycin; Erythropoietin; Heme; Iron Isotopes; Mice; Polycythemia; Reticulocytes; Spleen; Time Factors | 1968 |
Determination of a skin-related erythropoietic substance.
Topics: Animals; Biological Assay; Dehydration; Erythropoiesis; Erythropoietin; Fasting; Female; Heme; Iron; Iron Isotopes; Polycythemia; Rats; Skin; Skin Physiological Phenomena; Spectrophotometry; Talc; Tissue Extracts; Turpentine | 1968 |
Response of polycythemia vera marrow to erythropoietin in vitro.
Topics: Aged; Anemia, Hypochromic; Bone Marrow; Cell Differentiation; Erythropoiesis; Erythropoietin; Female; Heme; Humans; In Vitro Techniques; Male; Middle Aged; Polycythemia Vera | 1968 |
Hormonal regulation of pre-natal haemoglobin synthesis by erythropoietin.
Topics: Animals; Culture Techniques; Electrophoresis; Erythropoietin; Fetal Hemoglobin; Heme; Iron Isotopes; Liver; Mice; Rats; Spleen; Starch; Time Factors | 1968 |
Studies on extrarenal erythropoietin.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Culture Techniques; Erythropoietin; Heme; Humans; Hypoxia; Iron Isotopes; Kidney; Male; Nephrectomy; Neutralization Tests; Rats | 1969 |
Effect of erythropoietin on bone marrow delta-aminolevulinic acid synthetase and heme synthetase.
Topics: Acyltransferases; Amino Acids; Animals; Bone Marrow; Bone Marrow Cells; Culture Techniques; Erythropoietin; Heme; Iron Isotopes; Levulinic Acids; Mitochondria; Mixed Function Oxygenases; Puromycin; Rabbits; Sheep; Stimulation, Chemical | 1969 |
The effect of erythropoietin on hematopoietic organs of the polycythemic mouse.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Differentiation; DNA; Erythropoietin; Femur; Heme; Hemolysin Proteins; In Vitro Techniques; Iron Isotopes; Mice; Phosphorus Isotopes; Polycythemia; RNA; Spectrophotometry; Spleen | 1966 |
In vitro effect of erythropoietin on the spleen of the polycythemic mouse. 1.
Topics: Animals; Cell Differentiation; Cell Division; Erythrocytes; Erythropoietin; Female; Heme; In Vitro Techniques; Iron Isotopes; Mice; Polycythemia; Spleen | 1966 |
The effects of erythropoietin on haem synthesis in mouse yolk sac and cultured foetal liver cells.
Topics: Animals; Culture Techniques; Erythropoietin; Extraembryonic Membranes; Fetus; Heme; Iron Isotopes; Liver; Mice; Pentoses; Trypsin | 1966 |
Ontogenesis of erythrocytes and hemoglobin formation.
Topics: Amino Acid Sequence; Animals; Anura; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Chick Embryo; Chromatography, Ion Exchange; Erythrocytes; Erythropoietin; Heme; Hemoglobins; Humans; Iron; Models, Theoretical; Peptides; Reticulocytes; RNA | 1966 |
[The anemia of chronic renal insufficiency].
Topics: Anemia; Erythrocyte Aging; Erythropoietin; Heme; Hemoglobins; Hemolysis; Humans; Iron; Kidney Diseases; Kidney Failure, Chronic; Metabolic Diseases; Porphyrins; Uremia | 1966 |
[Studies on the mechanism of the action of erythropoietin with emphasis on stem cell differentiation].
Topics: Amino Acids; Animals; Cell Differentiation; Dactinomycin; Erythrocytes; Erythropoietin; Female; Globins; Heme; Hydro-Lyases; Iron Isotopes; Levulinic Acids; Ligases; Mice; Polycythemia; Spleen | 1966 |
[Clinical study on the red blood cell].
Topics: Adolescent; Adult; Aged; Anemia; Animals; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Humans; Male; Mice; Middle Aged | 1966 |
An in vitro assay of erythropoietin.
Topics: Animals; Antibodies; Biological Assay; Bone Marrow Cells; Culture Techniques; Dactinomycin; Dogs; Erythropoietin; Heme; Iron; Iron Isotopes; Trypsin | 1967 |
In vitro effect of erythropoietin on the spleen of the polycythemic mouse. II. Radiosensitivity of stem cells.
Topics: Animals; Cell Differentiation; Culture Techniques; Erythropoiesis; Erythropoietin; Heme; Iron Isotopes; Mice; Polycythemia; Radiation Effects; Spleen | 1967 |
Effect of erythropoietin on DNA synthesis by erythroblasts in vitro.
Topics: Animals; Autoradiography; Bone Marrow; DNA; Erythrocytes; Erythropoietin; Heme; In Vitro Techniques; Rats; RNA; Thymidine; Tritium | 1967 |
Erythropoietin-induced DNA synthesis in normoblasts in vitro: effect of Actinomycin-D.
Topics: Dactinomycin; DNA; Erythrocytes; Erythropoietin; Heme; In Vitro Techniques; Iron Isotopes; Thymidine; Tritium | 1967 |
Regulation of red cell and platelet production.
Topics: Animals; Blood Platelets; Bone Marrow; Bone Marrow Cells; Chemical Phenomena; Chemistry; Erythropoiesis; Erythropoietin; Hematopoiesis; Heme; Juxtaglomerular Apparatus; Kidney; Megakaryocytes; Mice; Rats; Swine; Thrombopoietin | 1967 |
Erythropoietin and its mode of action.
Topics: Animals; Cell Differentiation; Erythrocytes; Erythropoietin; Heme; Kinetics; Leukemia, Experimental; Mice; Molecular Weight; Rats; Receptors, Cell Surface; Receptors, Erythropoietin | 1984 |
Increased concentrations of cyclic GMP in fetal liver cells stimulated by erythropoietin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; DNA; Erythropoietin; Heme; Liver; Rats | 1981 |
Inhibition of heme synthesis in bone marrow cells by succinylacetone: effect on globin synthesis.
Topics: Animals; Biological Transport; Bone Marrow; Cells, Cultured; Erythropoietin; Globins; Heme; Heptanoates; Iron; Male; Protein Biosynthesis; Rats; RNA | 1983 |
Role of erythropoietin and cyclic nucleotides in erythroid cell proliferation in fetal liver.
Topics: Animals; Cell Cycle; Cyclic AMP; Cyclic GMP; DNA; Erythropoiesis; Erythropoietin; Fetus; Heme; Liver; Rats; Rats, Inbred Strains | 1980 |
Splenic erythroblasts in anemia-inducing Friend disease: a source of cells for studies of erythropoietin-mediated differentiation.
Topics: Anemia; Animals; Cell Count; Cell Differentiation; Erythroblasts; Erythropoietin; Female; Friend murine leukemia virus; Globins; Heme; Kinetics; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Polycythemia; Spleen | 1984 |
The selective enhancing influence of hemin and products of human erythrocytes on colony formation by human multipotential (CFUGEMM) and erythroid (BFUE) progenitor cells in vitro.
Topics: Bone Marrow Cells; Cell Communication; Cell Separation; Colony-Forming Units Assay; Erythrocytes; Erythropoietin; Granulocytes; Hematopoietic Stem Cells; Heme; Hemin; Humans; Macrophages | 1983 |
[Inhibition of heme biosynthesis in erythroid precursors (BFU-e) isolated from human peripheral blood: effects on globin synthesis].
Topics: Chromatography, Ion Exchange; Deferoxamine; Erythroblasts; Erythropoietin; Globins; Heme; Humans; Kinetics; Protein Biosynthesis | 1983 |
Erythropoiesis in the aged mouse: II. Response to stimulation in vitro.
Topics: Aging; Animals; Cell Division; DNA; Erythropoiesis; Erythropoietin; Female; Hematopoietic Stem Cells; Heme; In Vitro Techniques; Iron; Mice; Mice, Inbred C57BL; Thymidine | 1984 |
The effect of parathyroid hormone on erythropoiesis in serum-free cultures of fetal mouse liver cells.
Topics: Animals; Calcium; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Egtazic Acid; Erythropoiesis; Erythropoietin; Guinea Pigs; Heme; Liver; Parathyroid Hormone | 1981 |
Specific differentiation events induced by erythropoietin in cells infected in vitro with the anemia strain of Friend virus.
Topics: Animals; Cell Differentiation; Cell Transformation, Viral; Cells, Cultured; Erythroblasts; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Globins; Heme; Mice; RNA, Messenger; Spectrin; Transcription, Genetic | 1982 |
Measurement of human serum erythropoietin by erythroid colony-forming technique using fetal mouse liver cells.
Topics: Anemia; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Erythropoietin; Female; Fetus; Heme; Humans; Iron Radioisotopes; Liver; Male; Mice; Mice, Inbred C57BL; Pregnancy | 1982 |
Endotoxin-induced suppression of erythropoiesis: the role of erythropoietin and a heme synthesis stimulating factor.
Topics: Animals; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Erythropoiesis; Erythropoietin; Female; Heme; Iron; Mice | 1982 |
Anaemia in patients with myelomatosis.
Topics: Adult; Aged; Anemia; Blood Volume; Bone Marrow; Creatinine; Erythrocytes; Erythropoietin; Female; Heme; Hemoglobinometry; Humans; Immunoglobulins; Iron; Male; Middle Aged; Multiple Myeloma; Paraproteins; Urea | 1982 |
Erythroblast iron metabolism in sideroblastic marrows.
Topics: Adult; Aged; Aminolevulinic Acid; Anemia, Sideroblastic; Bone Marrow; Cytoplasm; Erythroblasts; Erythrocyte Indices; Erythrocytes; Erythropoietin; Female; Ferritins; Heme; Humans; Iron; Male; Middle Aged; Mitochondria; Pyridoxal Phosphate | 1982 |
[A case of pure red cell aplasia associated with pregnancy and bone marrow cells responsive to erythropoietin in vitro (author's transl)].
Topics: Adult; Anemia, Aplastic; Bone Marrow; Erythropoietin; Female; Heme; Humans; In Vitro Techniques; Pregnancy; Pregnancy Complications, Hematologic | 1980 |
Stimulation of erythroblast formation in suspension cultures of murine marrow by a factor in normal mouse serum, and its relationship to erythropoietin.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Culture Media; Erythroblasts; Erythrocyte Count; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Heme; Mice; Polycythemia | 1980 |
[Pathogenesis of anemia in collagen disease. I. Effects of erythropoietin and rheumatoid arthritis (RA) patient's sera on the heme synthesis of normal and RA patient's bone marrow erythroblasts (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Bone Marrow; Erythroblasts; Erythrocytes; Erythropoietin; Female; Heme; Humans; Male; Middle Aged | 1981 |
Investigations into the in vitro sensitivity to erythropoietin of haematopoietic tissue from ex-hypoxic, erythrocytotic mice.
Topics: Animals; Bone Marrow; Cell Extracts; Cells, Cultured; Erythrocytes; Erythropoietin; Female; Heme; Hypoxia; Mice; Mice, Inbred C3H; Polycythemia; Spleen | 1980 |
A quantitative bioassay for erythropoietin, using mouse bone marrow.
Topics: Animals; Biological Assay; Bone Marrow; Cells, Cultured; Erythropoietin; Heme; Iron; Liver; Mice; Transferrin | 1981 |
Determination of normal human serum erythropoietin levels, using mouse bone marrow.
Topics: Animals; Biological Assay; Bone Marrow; Cells, Cultured; Erythropoietin; Heme; Humans; Iron; Mice | 1981 |
In vitro assay of erythropoietin in fetal mouse liver cultures. I. Comparison of radioactive tracers and evidence of assay specificity.
Topics: Animals; Biological Assay; Culture Techniques; DNA; Dose-Response Relationship, Drug; Erythropoietin; Fetus; Heme; Humans; Idoxuridine; Liver; Mice; Thymidine | 1981 |
Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells.
Topics: Apoptosis; Cells, Cultured; DNA; Erythroid Precursor Cells; Erythropoietin; Hematopoietic Cell Growth Factors; Heme; Humans; Insulin-Like Growth Factor I; Recombinant Proteins; Stem Cell Factor | 1994 |
Erythropoietin exerts transcriptional and translational control over globin synthesis in J2E cells.
Topics: Cell Line, Transformed; Erythroblasts; Erythropoietin; Globins; Heme; Humans; Liver; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1995 |
Cellular ferritin uptake: a highly regulated pathway for iron assimilation in human erythroid precursor cells.
Topics: Apoferritins; Apoproteins; Cells, Cultured; Erythropoietin; Female; Ferritins; Gene Expression; Hematopoietic Stem Cells; Heme; Humans; Iron; Iron-Regulatory Proteins; Leukocytes; Placenta; Pregnancy; RNA-Binding Proteins; Transferrin | 1994 |
Differential effects of iron and iron carrier on hematopoietic cells differentiation and human ADA gene transfer.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Division; Cells, Cultured; DNA; Erythropoietin; Female; Fluorouracil; Genetic Vectors; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Heme; Humans; Iron; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Porphobilinogen Synthase; Rats; Rats, Sprague-Dawley; Retroviridae; Transfection | 1994 |
Inhibition of heme synthesis induces apoptosis in human erythroid progenitor cells.
Topics: Apoptosis; Cells, Cultured; Culture Media; Erythroid Precursor Cells; Erythropoietin; Ferritins; Heme; Heptanoates; Humans; Isoniazid; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Stem Cells; Transferrin | 1995 |
Effect of exogenous erythropoietin on haem synthesis in anaemic patients with rheumatoid arthritis.
Topics: Adult; Aged; Anemia; Arthritis, Rheumatoid; Erythrocytes; Erythropoietin; Female; Heme; Hemoglobins; Humans; Male; Middle Aged; Protoporphyrins | 1994 |
Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment.
Topics: Anemia; Animals; Body Weight; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Drug Synergism; Erythropoietin; Female; Hematopoiesis; Hematopoietic Stem Cells; Heme; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neutropenia; Thrombocytopenia; Weight Loss; Zidovudine | 1993 |
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
Topics: Animals; Cobalt; Cycloheximide; Endothelial Growth Factors; Erythropoietin; Gene Expression Regulation; Genes, fos; Genes, jun; Heme; Humans; Hypoxia; In Vitro Techniques; Lymphokines; Oxygen; Rats; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1994 |
Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells.
Topics: Carcinoma, Hepatocellular; Cobalt; Erythropoietin; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Humans; Liver Neoplasms; Metalloporphyrins; Protoporphyrins; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Heme synthesis in chronic renal failure: the effects of hemodialysis, peritoneal dialysis and erythropoietin treatment.
Topics: Adult; Erythrocytes; Erythropoietin; Female; Hematocrit; Heme; Humans; Hydroxymethylbilane Synthase; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Porphyrins; Recombinant Proteins; Reference Values; Renal Dialysis; Reticulocyte Count | 1995 |
Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, inhibits erythropoietin-induced erythroid differentiation of K562 cells.
Topics: Androstadienes; Cell Differentiation; Cell Line; Enzyme Inhibitors; Erythropoietin; Gene Expression; Glycophorins; Heme; Hemoglobins; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Wortmannin | 1996 |
Effects of recombinant human erythropoietin on porphyrin metabolism in uremic patients on hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Erythrocytes; Erythropoietin; Female; Follow-Up Studies; Hematocrit; Heme; Hemoglobins; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Porphobilinogen Synthase; Porphyrins; Recombinant Proteins; Renal Dialysis; Uremia; Zinc | 1996 |
[Ineffective erythropoiesis and apoptosis].
Topics: Apoptosis; DNA; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Heme; Humans | 1996 |
Defective expression of the SHP-1 phosphatase in polycythemia vera.
Topics: Cell Differentiation; Colony-Forming Units Assay; Enzyme Induction; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Heme; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Polycythemia Vera; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-kit; Receptors, Erythropoietin; Receptors, Interleukin-3; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1999 |
Red blood cell degradation products modify responsiveness of erythropoietin gene to hypoxia.
Topics: Animals; Erythrocytes; Erythropoietin; Heating; Heme; Hemin; Hypoxia; Kidney Cortex; Male; Metalloporphyrins; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Protoporphyrins; RNA, Messenger | 1999 |
Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis.
Topics: Cell Survival; Deferoxamine; Enzyme Inhibitors; Erythropoietin; Heme; Heptanoates; Humans; Isoniazid; Protoporphyrins; Tumor Cells, Cultured | 2000 |
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.
Topics: Anemia; Animals; Biological Transport; Cation Transport Proteins; CHO Cells; Cricetinae; Endosomes; Erythrocyte Membrane; Erythrocytes; Erythroid Precursor Cells; Erythropoietin; Fluorescent Antibody Technique; Heme; Hemoglobins; Homozygote; Iron; Iron-Binding Proteins; Leukemia, Erythroblastic, Acute; Mice; Mice, Mutant Strains; Microscopy, Confocal; Mutation; Phenylhydrazines; Protein Isoforms; Reticulocyte Count; Reticulocytes; Spleen; Transferrin; Tumor Cells, Cultured | 2001 |
Erythroid 5-aminolevulinate synthase, ferrochelatase and DMT1 expression in erythroid progenitors: differential pathways for erythropoietin and iron-dependent regulation.
Topics: 5-Aminolevulinate Synthetase; Animals; Biological Transport; Cation Transport Proteins; Cells, Cultured; Erythroid Precursor Cells; Erythropoietin; Ferrochelatase; Genes, Reporter; Heme; Humans; Iron; Iron-Binding Proteins; Mice; RNA, Messenger; Transcription, Genetic | 2002 |
Zinc protoporphyrin/heme as an indicator of iron status in NICU patients.
Topics: Biomarkers; Blood Cell Count; Erythrocyte Transfusion; Erythropoietin; Ferrous Compounds; Gestational Age; Heme; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Iron Deficiencies; Protoporphyrins; Recombinant Proteins; Reference Values; Risk Factors | 2003 |
THE EFFECT OF ERYTHROPOIETIN UPON HEME SYNTHESIS BY MARROW CELLS IN VITRO.
Topics: Bone Marrow; Epoetin Alfa; Erythropoietin; Fasting; Heme; In Vitro Techniques; Iron Isotopes; Metabolism; Pharmacology; Rats; Research; Tissue Culture Techniques | 1963 |
STUDIES ON THE HEME SYNTHESIS BY BONE MARROW CELLS IN VITRO AND IN VIVO WITH 2-14C-GLYCINE. I. IN VITRO HEME SYNTHESIS AS AN ASSAY METHOD OF ERYTHROPOIETIC FACTOR IN SERUM.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Epoetin Alfa; Erythropoietin; Glycine; Heme; In Vitro Techniques; Lagomorpha; Proteins; Rabbits; Research | 1964 |
STUDIES ON THE EFFECTS OF ERYTHROPOIETIN UPON MARROW CELLS IN VITRO.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography; Epoetin Alfa; Erythropoietin; Heme; Hemoglobins; In Vitro Techniques; Iron Isotopes; Nucleosides; Pharmacology; Rats; Research; RNA; Tissue Culture Techniques | 1964 |
[STUDIES ON ERYTHROPOIETIN. 23. EFFECT OF ERYTHROPOIETIN ON HEME SYNTHESIS IN THE SPLEEN].
Topics: Biochemical Phenomena; Epoetin Alfa; Erythropoietin; Heme; Metabolism; Pharmacology; Spleen | 1965 |
Bcl-x(L) prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Erythroblasts; Erythropoiesis; Erythropoietin; Heme; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-bcl-2; Reticulocytes | 2005 |
Erythrocyte zinc protoporphyrin is elevated with prematurity and fetal hypoxemia.
Topics: Erythrocyte Indices; Erythrocytes; Erythropoietin; Female; Ferritins; Fetal Blood; Fetal Diseases; Fetal Growth Retardation; Gestational Age; Heme; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Insulin; Pregnancy; Pregnancy in Diabetics; Protoporphyrins; Reticulocyte Count | 2005 |
A simple method for enrichment of polychromatic erythroblasts from rat bone marrow, and their proliferation and maturation in vitro.
Topics: Aging; Animals; Bone Marrow Cells; Cell Count; Cell Culture Techniques; Cell Proliferation; Cell Separation; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Erythroblasts; Erythropoiesis; Erythropoietin; Female; Heme; Rats; Rats, Sprague-Dawley | 2011 |
A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells.
Topics: alpha-Globins; Aminolevulinic Acid; Butyric Acid; Cell Differentiation; Cell Proliferation; Erythroid Cells; Erythropoiesis; Erythropoietin; Ferrochelatase; Glycophorins; Heme; Hemoglobins; Humans; Hydrolysis; Hydroxymethylbilane Synthase; K562 Cells; Leukemia, Erythroblastic, Acute; Levulinic Acids; Prodrugs; RNA, Messenger | 2012 |
Erythropoietin Levels Increase during Cerebral Malaria and Correlate with Heme, Interleukin-10 and Tumor Necrosis Factor-Alpha in India.
Topics: Adult; Antigens, Protozoan; Chemokine CCL2; Erythropoietin; Female; Heme; Hemopexin; Humans; India; Interleukin-10; Malaria, Cerebral; Male; Plasmodium falciparum; Protozoan Proteins; Severity of Illness Index; Tumor Necrosis Factor-alpha; Young Adult | 2016 |
PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis.
Topics: Anemia; Animals; Biological Transport, Active; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Cytokines; DNA-Binding Proteins; Erythrocytes; Erythropoietin; Ferritins; Heme; Humans; Iron; Mice; Mice, Transgenic; Mitochondria; Muscle Proteins; Nuclear Receptor Coactivators; RNA-Binding Proteins | 2017 |
Erythropoietin signaling regulates heme biosynthesis.
Topics: A Kinase Anchor Proteins; Animals; Cyclic AMP-Dependent Protein Kinases; Erythropoietin; GATA1 Transcription Factor; Heme; Humans; Mice; Mitochondrial Membranes; Signal Transduction; Zebrafish | 2017 |
Zinc Protoporphyrin-to-Heme Ratio and Ferritin as Measures of Iron Sufficiency in the Neonatal Intensive Care Unit.
Topics: Biomarkers; Erythrocyte Transfusion; Erythropoietin; Female; Ferritins; Heme; Hospitalization; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Iron; Male; Protoporphyrins; Retrospective Studies; Sepsis | 2018 |
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.
Topics: Animals; Erythroid Cells; Erythropoiesis; Erythropoietin; Ferrochelatase; HEK293 Cells; Heme; Humans; Iron; Membrane Proteins; Mice; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Protein Transport | 2018 |
Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo.
Topics: Erythropoiesis; Erythropoietin; Female; Heme; Hemoglobins; Humans; Iron; Iron Overload; Pregnancy; Proteome; Sulfur | 2022 |