heme has been researched along with leucine in 141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 96 (68.09) | 18.7374 |
| 1990's | 16 (11.35) | 18.2507 |
| 2000's | 23 (16.31) | 29.6817 |
| 2010's | 6 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fudenberg, HH; Gemsa, D; Schmid, R; Webb, D; Woo, CH | 1 |
| Woods, JS | 1 |
| Franco, RS; Hogg, JW; Martelo, OJ | 1 |
| Arnstein, HR; Bonanou-Tzedaki, SA; Sheeran, BA; Smith, KE | 1 |
| Glenn, AR; May, BK | 1 |
| Fuhr, JE; Townes, TM | 1 |
| Minakami, S; Nakamura, M; Yasukochi, Y | 2 |
| Cahn, F; Lubin, M | 1 |
| Cimadevilla, JM; Hardesty, B | 1 |
| Hurst, R; Matts, RL | 1 |
| Cutler, RL; Davies, AM; Greenwood, C; Mauk, AG; Moore, GR; Pielak, GJ; Smith, M; Thurgood, AG; Williamson, DJ | 1 |
| Kraut, J; Miller, MA; Smulevich, G; Spiro, TG | 1 |
| Oyedeji, CO; Samaan, NA; Thompson, MM; Vassilopoulou-Sellin, R | 1 |
| Arnljots, K; Olsson, I | 1 |
| Garner, CD; Johnson, JT; Lee, EW | 1 |
| Omura, T; Sadano, H | 1 |
| Chui, LC; Gabuzda, TG; Lewis, HB; Silver, RK | 1 |
| Granick, S; Sassa, S | 1 |
| Gross, M | 3 |
| Gayathri, AK; Padmanaban, G | 1 |
| Fuhr, JE; Gengozian, N | 1 |
| Weiss, H; Ziganke, B | 1 |
| Kleinow, W; Lorenz, B; Weiss, H | 1 |
| Beattie, DS | 1 |
| Gnarra, DJ; Green, D; Honig, GR; Mason, RG; Maurer, HS; Shamsuddin, M; Vida, LN | 1 |
| Machleidt, W; Otto, J; Sebald, W | 1 |
| Brayley, A; Hunt, T; Jackson, RJ; Legon, S | 1 |
| Piddington, SK; White, JM | 1 |
| Higashi, T; Kawamata, F; Sakamoto, T | 1 |
| Freedman, ML; Geraghty, M; Rosman, J | 1 |
| Ali, MA; Brain, MC | 1 |
| Gross, M; Rabinovitz, M | 3 |
| Comi, P; Gianni, AM; Giglioni, B; Ottolenghi, S; Rungger, D | 1 |
| Clemens, MJ; Henshaw, EC; London, IM; Rahamimoff, H | 1 |
| Rabinovitz, M | 1 |
| Basch, RS; Malathi, VG; Silber, R | 1 |
| Koga, Y; Kusaka, I | 1 |
| Adamson, SD; Herbert, E; Yau, PM; Zucker, WV | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Labie, D; Solal, MC | 1 |
| Linder, MC; Moor, JR; Munro, HN; Scott, LE | 1 |
| Desalu, O; Lodish, HF | 1 |
| Grasso, JA | 1 |
| Ali, MA; White, JM | 1 |
| Shaeffer, JR | 1 |
| Dupont, CH | 1 |
| Herbert, E; Ivey, JL; Woodward, WR | 1 |
| Love, WE; Padlan, EA | 1 |
| Schimke, RT | 1 |
| De Duve, C; Lazarow, PB | 1 |
| London, IM; Tabill, AS; Vanderhoff, GA | 1 |
| Dehlinger, PJ; Schimke, RT | 1 |
| Ginsberg, M; Josephson, AS; Levere, RD; Lowenthal, I; Swerdlow, F | 1 |
| Fisher, JM; Mizuno, S; Rabinovitz, M | 1 |
| Freeman, KB; Lai, H; Rothwell, D; Sweeney, G | 1 |
| Garrard, WT | 1 |
| Ganzoni, A; Heywood, JD; Hillman, RS | 1 |
| Kamper, CS; Maxwell, CR; Rabinovitz, M | 1 |
| Gibson, QH; Jenkins, T; Nagel, RL | 1 |
| González, M; González-Cadavid, NF; Ortega, JP | 1 |
| Glatthaar, B; Winterhalter, KH | 1 |
| Fisher, JM; Freedman, ML; Maxwell, CR; Rabinovitz, M | 1 |
| Anderson, WF; Gilbert, JM | 1 |
| Ali, MA; Brain, MC; White, JM | 2 |
| Garner, RC; McLean, AE | 1 |
| Bond, EJ; De Matteis, F | 1 |
| Jacq, C; Lederer, F | 1 |
| Waxman, HS | 1 |
| Alvares, AP; Kuntzman, R; Levin, W | 1 |
| Albin, R; Aschenbrenner, B; Druyan, R; Rabinowitz, M | 1 |
| Adamson, SD; Herbert, E; Howard, GA | 1 |
| Bock, KW; Siekevitz, P | 1 |
| Bessman, SP; Hammel-Dupont, CL | 1 |
| Liang, K; Morris, AJ | 1 |
| Bradley, TB; Rieder, RF | 1 |
| Bargellesi, A; Conconi, F; Pontremoli, S | 1 |
| King, DW; King, ME | 1 |
| Jobe, A; Schulman, HM | 1 |
| Alperin, JB; Brimhall, B; Jones, RT; Schneider, RG; Ueda, S | 1 |
| Hollender, A; Lehmann, H; Lorkin, PA; Svensson, B | 1 |
| Evans, RF; Shaeffer, JR; Trostle, PK | 1 |
| Honig, GR; Mason, RG; Rowan, BQ | 1 |
| Gribble, TJ; Schwartz, HC | 1 |
| Bessman, SP; Hammel, CL | 2 |
| Limbosch, S; Malpoix, P | 1 |
| Schulman, HM; Zucker, WV | 1 |
| Hardesty, B; Henderson, AB; Kramer, G | 1 |
| Cirotto, C; Fucci, L; Geraci, G; Tomei, L | 1 |
| Ibraham, NG; Levere, RD; Lutton, JD | 1 |
| Hayashi, N; Kikuchi, G | 1 |
| Dresner, DL; Ibrahim, NG; Levere, RD; Mascarenhas, BR | 1 |
| Suzuki, H | 1 |
| Gennis, RB; Georgiou, C; Ghaim, JB; Kaysser, TM | 1 |
| Brayer, GD; Guillemette, JG; Lo, TP; Murphy, ME; Smith, M | 1 |
| Lisowski, M; Picur, B; Poerio, E; Taniuchi, H | 1 |
| Bardakdjian, J; Galacteros, F; Harousseau, JL; Kister, J; M'Rad, A; Milpied, N; Promé, D; Rapp, MJ; Riou, J; Wajcman, H | 1 |
| Gamboa de Domínguez, ND; Rosenthal, PJ | 1 |
| Battle, A; Fukuda, H; Riley, P; Washbrook, R | 1 |
| Ferrone, FA; Himanen, JP; Liao, D; Manning, JM; Martin de Llano, JJ | 1 |
| Bogumil, R; Brayer, GD; Luo, Y; Mauk, AG; Maurus, R; Overall, CM; Smith, M | 1 |
| Ishimori, K; Morishima, I; Uchida, T | 1 |
| Chien, EY; Friedman, JM; Peterson, ES; Sligar, SG | 1 |
| Lu, Y; Wang, X | 1 |
| Dawson, JH; Lu, Y; Pond, AE; Sigman, JA | 1 |
| Hendrich, MP; Ho, C; Ho, NT; Jeong, ST | 1 |
| Boffi, A; Chiancone, E; Giangiacomo, L; Guarrera, L; Spagnuolo, C | 1 |
| Hillar, A; Loboda, A; Loewen, PC; Mauk, AG; Pauls, R; Peters, B; Zhang, H | 1 |
| Ihara, M; Ishimori, K; Morishima, I; Takahashi, S | 1 |
| Daff, S; Sagami, I; Sato, Y; Shimizu, T | 1 |
| Ishikawa, H; Ishimori, K; Morishima, I; Takahashi, S; Uchida, T | 1 |
| Cao, W; Champion, PM; Christian, JF; Rosca, F; Sage, JT | 1 |
| Antholine, W; Ferguson-Miller, S; Kang, UG; Schmidt, B; Zhen, Y | 1 |
| Jones, DK; Patel, N; Raven, EL | 1 |
| Boffi, A; Draghi, F; Miele, AE; Vallone, B | 1 |
| Kerby, RL; Roberts, GP; Youn, H | 1 |
| Erman, JE; Foshay, M; Satterlee, JD; Savenkova, MI | 1 |
| Colas, C; De Montellano, PR | 1 |
| Akutsu, H; Harada, E; Kobayashi, R; Ozawa, K; Takayama, Y | 1 |
| Hoashi, Y; Ishikawa, Y; Tomisugi, Y; Uno, T; Yamashita, T | 1 |
| Olson, JS; Phillips, GN; Zhang, W | 1 |
| Guo, Z; Lu, Y; Wang, Z; Yeung, N; Zhao, X | 1 |
| Lu, Y; Nilges, MJ; Zhao, X | 1 |
| Giovannelli, JL; Ho, C; Ho, NT; Lukin, JA; Simplaceanu, V; Wiltrout, ME | 1 |
| Araki, Y; Igarashi, J; Ito, O; Kurokawa, H; Shimizu, T; Yokota, N | 1 |
| Akimoto, S; Endou, S; Miyoshi, H; Mogi, T; Morimoto-Tadokoro, M | 1 |
| Bröcker, MJ; Ganskow, S; Heathcote, P; Heinz, DW; Jahn, D; Moser, J; Schubert, WD; Virus, S | 1 |
| Bondlela, M; Chen, B; Haines, DC; Hegde, A; Machius, M; Peterson, JA; Tomchick, DR | 1 |
| Belevich, I; Bloch, DA; Borisov, VB; Mogi, T; Verkhovsky, MI | 1 |
| Aono, T; Hori, H; Miura, M; Sakamoto, Y; Takeuchi, F; Tsubaki, M | 1 |
| Igarashi, J; Kitanishi, K; Kobayashi, K; Kobayashi, N; Nakajima, K; Shimizu, T | 1 |
| Andrew, CR; Eady, RR; Garton, EM; Hasnain, SS; Petersen, CA; Pixton, DA | 1 |
| Greetham, GM; Hardman, SJ; Hay, S; Heyes, DJ; Hough, MA; Russell, HJ; Scrutton, NS; Towrie, M | 1 |
| Kitanishi, K; Man, P; Martínek, V; Martínková, M; Muchová, L; Shimizu, T; Stiborová, M; Stranava, M; Vítek, L | 1 |
| Al Haddad, A; Auböck, G; Chergui, M; Monni, R; van Mourik, F | 1 |
1 review(s) available for heme and leucine
| Article | Year |
|---|---|
Regulation by heme of synthesis and intracellular translocation of delta-aminolevulinate synthase in the liver.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Biological Transport; Cell-Free System; Cobalt; Cytosol; Dicarbethoxydihydrocollidine; Heme; Hemin; Immunodiffusion; Leucine; Liver; Mitochondria, Liver; Molecular Weight; Protoporphyrins; Rabbits; Rats; Tryptophan Oxygenase | 1981 |
140 other study(ies) available for heme and leucine
| Article | Year |
|---|---|
Erythrophagocytosis by macrophages: suppression of heme oxygenase by cyclic AMP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Antibodies; Ascitic Fluid; Bilirubin; Bucladesine; Carbon Radioisotopes; Catecholamines; Cell Separation; Cyclic AMP; Enzyme Activation; Erythrocytes; Female; Glucose; Heme; Iron Radioisotopes; Leucine; Macrophages; Oxygenases; Phagocytosis; Prostaglandins; Rabbits; Rats; RNA; Theophylline; Tritium; Uridine | 1975 |
Heme regulation of cytochrome oxidase synthesis in fetal rat liver.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cobalt; Cycloheximide; Electron Transport Complex IV; Female; Fetus; Heme; In Vitro Techniques; Leucine; Mitochondria, Liver; Pregnancy; Rats; Time Factors | 1977 |
Asynchronous globin chain synthesis in rabbit reticulocyte lystates induced by hemin-controlled repressor.
Topics: Animals; Female; Globins; Heme; Hemin; Leucine; Rabbits; Reticulocytes; Time Factors | 1978 |
The high-temperature inactivation of rabbit reticulocyte lysates by a haemin-independent mechanism.
Topics: Animals; Cell-Free System; Cytosol; Ethylmaleimide; Heme; Hemin; In Vitro Techniques; Leucine; Methionine; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; Temperature | 1978 |
Effect of haemin on endogenous protein synthesis in oocytes of the Queensland cane toad Bufo marinus.
Topics: Animals; Bufo marinus; Depression, Chemical; Female; Heme; Hemin; Leucine; Oocytes; Ovum; Phenylalanine; Protein Biosynthesis; Valine | 1975 |
Protection by cycloheximide from hyperthermic inhibition of protein synthesis in human reticulocytes.
Topics: Cycloheximide; Female; Fetal Blood; Heme; Hemoglobins; Hot Temperature; Humans; Infant, Newborn; Isoniazid; Leucine; Pregnancy; Reticulocytes; Time Factors | 1977 |
Effect of cobalt on the synthesis of liver microsomal cytochromes.
Topics: Aminolevulinic Acid; Animals; Cobalt; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Leucine; Male; Microsomes, Liver; Protein Biosynthesis; Rats; Trypsin | 1977 |
Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin.
Topics: Animals; Escherichia coli; Globins; Heme; Hemin; Leucine; Leucine-tRNA Ligase; Liver; Methionine; Methionine-tRNA Ligase; N-Formylmethionine; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Reticulocytes; RNA; RNA, Transfer; Valine; Valine-tRNA Ligase | 1975 |
Evidence for a non-hemin regulated translational repressor in Friend leukemia virus transformed murine proerythroblasts.
Topics: Animals; Blood Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Friend murine leukemia virus; Heme; Hemin; Leucine; Mice; Neoplasm Proteins; Protein Biosynthesis; Rabbits; Reticulocytes; Species Specificity; Spleen; Time Factors | 1975 |
The relationship between protein synthesis and heat shock proteins levels in rabbit reticulocyte lysates.
Topics: Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cell-Free System; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Heme; Kinetics; Leucine; Phosphorus Radioisotopes; Protein Biosynthesis; Rabbits; Reticulocytes | 1992 |
Change in charge of an unvaried heme contact residue does not cause a major change of conformation in cytochrome c.
Topics: Alanine; Arginine; Cytochrome c Group; Electrochemistry; Heme; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Mutagenesis; Protein Conformation; Saccharomyces cerevisiae | 1991 |
Conformational change and histidine control of heme chemistry in cytochrome c peroxidase: resonance Raman evidence from Leu-52 and Gly-181 mutants of cytochrome c peroxidase.
Topics: Alkenes; Base Sequence; Carbon Monoxide; Cytochrome-c Peroxidase; DNA Mutational Analysis; Ferric Compounds; Ferrous Compounds; Glycine; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Molecular Sequence Data; Oligonucleotides; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Structure-Activity Relationship; Water | 1991 |
Heme inhibits cartilage metabolism and growth in vitro.
Topics: Animals; Biological Assay; Cartilage; Chick Embryo; Dose-Response Relationship, Drug; Embryo, Mammalian; Heme; In Vitro Techniques; Leucine; Organ Size; Proteoglycans; Rats; Rats, Inbred Strains; Sulfates; Uridine | 1989 |
Myeloperoxidase precursors incorporate heme.
Topics: Aminolevulinic Acid; Cell Line; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Granulocytes; Heme; Humans; Immunosorbent Techniques; Leucine; Levulinic Acids; Molecular Weight; Peptide Fragments; Peroxidase; Protein Precursors; Serine Endopeptidases | 1987 |
A proposed role played by benzene itself in the induction of acute cytopenia: inhibition of DNA synthesis.
Topics: Administration, Inhalation; Animals; Benzene; Bone Marrow; Cell Count; DNA; Female; Heme; Leucine; Mice; Mice, Inbred ICR; Nucleic Acid Synthesis Inhibitors; Protein Biosynthesis; Thymidine | 1988 |
Incorporation of heme to microsomal cytochrome P-450 in the absence of protein biosynthesis.
Topics: Aminolevulinic Acid; Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Heme; In Vitro Techniques; Leucine; Male; Microsomes, Liver; Phenobarbital; Precipitin Tests; Rats; Rats, Inbred Strains | 1985 |
The formation of foetal and adult haemoglobin in cell cultures of neonatal calf marrow.
Topics: Animals; Animals, Newborn; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cattle; Culture Techniques; Erythropoietin; Fetal Hemoglobin; gamma-Globulins; Heme; Hemoglobins; Iron; Iron Isotopes; Isoleucine; Leucine; Stimulation, Chemical | 1970 |
Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acyltransferases; Allyl Compounds; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Depression, Chemical; Enzyme Induction; Etiocholanolone; Half-Life; Heme; Hexachlorocyclohexane; Leucine; Liver; Orotic Acid; Pyridones; RNA, Messenger; Time Factors | 1970 |
Isolation and characterization of an antibody to a highly purified preparation of the hemin-controlled translational repressor from rabbit reticulocytes.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Blood Proteins; Carbon Radioisotopes; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Epitopes; Ethylmaleimide; Genes, Regulator; Guinea Pigs; Heme; Immunoglobulin G; Kinetics; Leucine; Peptide Chain Initiation, Translational; Rabbits; Reticulocytes; Time Factors; Ultrafiltration | 1974 |
Biochemical effects of 3,5-diethoxycarbonyl-1,4-dihydrocollidine in mouse liver.
Topics: Allylisopropylacetamide; Aniline Compounds; Animals; Carbon Radioisotopes; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dicarboxylic Acids; Female; Heme; Iron Radioisotopes; Kinetics; Leucine; Lipid Metabolism; Liver; Mice; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Organ Size; Phenobarbital; Phospholipids; Protein Biosynthesis; Pyridines; Ribonucleases; RNA | 1974 |
Coordination of heme and globin synthesis in primate reticulocytes.
Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Globins; Haplorhini; Heme; Hemoglobins; Isoniazid; Kinetics; Leucine; Levulinic Acids; Reticulocytes; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
Cytochrome b in Neurospora crassa mitochondria. Site of translation of the heme protein.
Topics: Chloramphenicol; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Cytochromes; Electrophoresis, Polyacrylamide Gel; Heme; Iron; Iron Radioisotopes; Leucine; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Oxidation-Reduction; Protein Biosynthesis; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Mitochondrial translation of cytochrome b in Neurospora crassa and Locusta migratoria.
Topics: Animals; Apoproteins; Cycloheximide; Cytochromes; DNA; Electrophoresis, Polyacrylamide Gel; Grasshoppers; Heme; Leucine; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Oxidation-Reduction; Protein Biosynthesis; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Tritium | 1974 |
The possible relationship between heme synthesis and mitochondrial biogenesis.
Topics: Acetamides; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cytochromes; Electron Transport Complex IV; Enzyme Induction; Glycine; Heme; Leucine; Levulinic Acids; Male; Mitochondria, Liver; Rats; Stimulation, Chemical; Succinates; Triazoles; Tritium | 1971 |
Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable variant producing severe hemolytic disease.
Topics: Adult; Amino Acids; Anemia, Hemolytic; Carbon Isotopes; Carbon Monoxide; Chemical Precipitation; Chromatography, Ion Exchange; Chromium Isotopes; Electrophoresis; Erythrocytes; Female; Half-Life; Heme; Hemoglobins, Abnormal; Hot Temperature; Humans; Hydroxymercuribenzoates; Inclusion Bodies; Leucine; Methemoglobin; Proline; Reticulocytes; Sulfites | 1973 |
Products of mitochondrial protein synthesis in Neurospora crassa. Determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis.
Topics: Amino Acids; Carbon Radioisotopes; Chloramphenicol; Cycloheximide; Dialysis; Drug Resistance, Microbial; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Heme; Leucine; Membranes; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Peptides; Sodium Dodecyl Sulfate; Spectrophotometry; Tritium | 1973 |
The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates.
Topics: Animals; Blood Proteins; Carbon Radioisotopes; Cell-Free System; Cyclic AMP; Glutathione; Heme; Kinetics; Leucine; Methionine; Oxidation-Reduction; Penicillium chrysogenum; Peptide Chain Initiation, Translational; Protein Biosynthesis; Purine Nucleotides; Purines; Rabbits; Reticulocytes; RNA; Stimulation, Chemical; Sulfur Radioisotopes | 1974 |
The effect of lead on total globin and alpha- and beta-chain synthesis; in vitro and in vivo.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Depression, Chemical; Female; Globins; Heme; Hemoglobinopathies; Hemoglobins; Humans; In Vitro Techniques; Lead; Leucine; Male; Puromycin; Radioisotopes; Reticulocytes; Tritium | 1974 |
Control of globin synthesis by hemin. An intermediate form of the translational repressor in rabbit reticulocyte lysates.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Cytosol; Drug Stability; Globins; Heme; Hemin; Hot Temperature; Kinetics; Leucine; Protein Binding; Protein Biosynthesis; Rabbits; Reticulocytes; Subcellular Fractions; Temperature; Time Factors; Ultracentrifugation | 1974 |
Studies on rat catalase. VII. Double-labeling of catalase by 14C-leucine and 3H-delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Antigen-Antibody Reactions; Carbon Radioisotopes; Catalase; Cell-Free System; Chromatography, DEAE-Cellulose; Cytoplasmic Granules; Cytosol; Heme; Isotope Labeling; Kinetics; Leucine; Levulinic Acids; Liver; Microsomes; Rabbits; Rats; Ribosomes; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
Hemin control of globin synthesis. Isolation of a hemin-reversible translational repressor from human mature erythrocytes.
Topics: Animals; Carbon Radioisotopes; Cell-Free System; Chromatography, Gel; Drug Stability; Erythrocytes; Globins; Heme; Hemin; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; Temperature; Time Factors; Trypsin | 1974 |
Ethanol inhibition of haemoglobin synthesis: in vitro evidence for a haem correctable defect in normal subjects and in alcoholics.
Topics: Alcoholism; Aminolevulinic Acid; Bone Marrow; Bone Marrow Cells; Chromatography; Ethanol; Globins; Heme; Hemoglobins; Humans; In Vitro Techniques; Leucine; Pyridoxine; Reticulocytes; Tritium | 1974 |
Effect of cobalt on the synthesis and degradation of hepatic catalase in vivo.
Topics: Aminolevulinic Acid; Animals; Catalase; Cobalt; Cytosol; Glycine; Heme; Kinetics; Leucine; Liver; Male; Mitochondria, Liver; Rats | 1974 |
Control of globin synthesis in cell-free preparations of reticulocytes by formation of a translational repressor that is inactivated by hemin.
Topics: Animals; Cell-Free System; Globins; Heme; In Vitro Techniques; Leucine; Peptide Chain Initiation, Translational; Rabbits; Reticulocytes; Temperature; Time Factors | 1972 |
Translational control of globin synthesis by haemin in Xenopus oocytes.
Topics: Animals; Carbon Radioisotopes; Female; Globins; Heme; Histidine; Iodine Radioisotopes; Lead; Leucine; Ovum; Polyribosomes; Protein Biosynthesis; Reticulocytes; Ribonucleases; RNA, Messenger; Tritium; Xenopus | 1973 |
Met-tRNAfMet binding to 40S ribosomal subunits: a site for the regulation of initiation of protein synthesis by hemin.
Topics: Animals; Blood Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Globins; Heme; Hemin; Leucine; Methionine; Molecular Weight; Peptide Chain Initiation, Translational; Protein Binding; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; Ribosomes; RNA, Transfer; Sulfur Radioisotopes | 1974 |
Translational repression in the control of globin chain initiation by hemin.
Topics: Animals; Carbon Radioisotopes; Centrifugation, Density Gradient; Codon; Cycloheximide; Globins; Heme; Hemin; Kinetics; Leucine; Methionine; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Reticulocytes; Ribose; Ribosomes; RNA, Messenger; RNA, Transfer; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Temperature; Time Factors | 1974 |
Nucleoside deaminase activity during the recovery of x-irradiated, bone marrow-protected mice.
Topics: Aminohydrolases; Animals; Blood Transfusion; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Isotopes; Cytidine; Female; Heme; Iron; Iron Isotopes; Leucine; Mice; Mice, Inbred Strains; Organ Size; Protein Biosynthesis; Radiation Effects; Spleen; Transplantation, Homologous; Tritium | 1972 |
Characterization of autolysed membranes of Bacillus cereus. Characterization in membrane biosynthesis and binding of hemes to proteins of membrane subfraction L10P.
Topics: Apoproteins; Bacillus cereus; Bacteriolysis; Carbon Isotopes; Cell Membrane; Centrifugation, Density Gradient; Cytochromes; Electrophoresis, Disc; Glycerol; Heme; Leucine; Phospholipases; Phospholipids; Protein Binding; Spheroplasts; Valine | 1972 |
Involvement of hemin, a stimulatory fraction from ribosomes and a protein synthesis inhibitor in the regulation of hemoglobin synthesis.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytoplasm; Female; Globins; Heme; Hemoglobins; Iron; Kinetics; Leucine; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Peptide Termination Factors; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; Subcellular Fractions; Tritium | 1972 |
Regulation of onset of rapid hemoglobin formation in chick blastodisc blood islands at the transcription and translation levels. A quantitative analysis of effects of actinomycin, ethanol, and heme precursors.
Topics: Animals; Chick Embryo; Culture Media; Dactinomycin; Ethanol; Female; Heme; Hemoglobins; Leucine; Levulinic Acids; Ovum; Porphyrins; Protein Biosynthesis; Protein Precursors; Stimulation, Chemical; Time Factors; Transcription, Genetic; Tritium; Uridine | 1972 |
Control of globin synthesis by hemin: factors influencing formation of an inhibitor of globin chain initiation in reticulocyte lysates.
Topics: Animals; Binding Sites; Blood Proteins; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Globins; Heme; Hemin; Kinetics; Leucine; Molecular Weight; Peptide Chain Initiation, Translational; Polyribosomes; Protein Binding; Rabbits; Reticulocytes; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Time Factors | 1972 |
A new case of hemoglobin Genova 2 2 28(B10) Leu leads to Pro. Further studies on the mechanism of instability and defective synthesis.
Topics: Amino Acids; Blood Protein Electrophoresis; Carbon Isotopes; Child; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Starch Gel; Genetics, Medical; Heme; Hemoglobins; Hemoglobins, Abnormal; Hot Temperature; Humans; Italy; Leucine; Macromolecular Substances; Male; Mutation; Oxygen; Partial Pressure; Peptides; Proline; Reticulocytes | 1973 |
Mechanism of sex difference in rat tissue iron stores.
Topics: Animals; Body Weight; Carbon Isotopes; Citrates; Female; Ferritins; Heme; Iron; Iron-Dextran Complex; Kidney; Leucine; Liver; Male; Myocardium; Organ Size; Organ Specificity; Quaternary Ammonium Compounds; Rats; Sex Factors | 1973 |
Control of globin synthesis by hemin. Effect of temperature on globin synthesis by the reticulocyte cell-free system and the activity of translational repressors formed in the absence of hemin.
Topics: Anemia; Animals; Carbon Isotopes; Cell-Free System; Globins; Heme; Hemolysis; Kinetics; Leucine; Phenylhydrazines; Protein Biosynthesis; Rabbits; Reticulocytes; Temperature; Time Factors; Trichloroacetic Acid | 1973 |
Regulation of synthesis of non-globin proteins in cell-free extracts of rabbit reticulocytes.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Blood Proteins; Carbon Isotopes; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Genetic Code; Globins; Heme; Hemolysis; Leucine; Methionine; Molecular Weight; Peptide Chain Elongation, Translational; Protein Biosynthesis; Rabbits; Reoviridae; Reticulocytes; RNA; RNA, Messenger; RNA, Viral; Sulfur Isotopes | 1973 |
Erythropoiesis in the newt, Triturus cristatus Laur. I. Identification of the 'erythroid precursor cell'.
Topics: Animals; Autoradiography; Blood Proteins; Cell Nucleus; Cytidine; Erythrocytes; Erythropoiesis; Hematopoietic Stem Cells; Heme; Hemoglobins; Leucine; Phenylhydrazines; Ribosomes; RNA; Splenectomy; Thymidine; Tritium; Triturus | 1973 |
Globin synthesis in sideroblastic anaemia. II. The effect of pyridoxine, -aminolaevulinic acid and haem, in vitro.
Topics: Adolescent; Anemia, Sideroblastic; Child; Erythrocytes; Globins; Heme; Humans; In Vitro Techniques; Leucine; Levulinic Acids; Male; Porphyrins; Pyridoxine; Reticulocytes; Tritium | 1973 |
Structure and synthesis of the unstable hemoglobin Sabin (alpha 2 beta 2--91 Leu leads to pro).
Topics: Amino Acid Sequence; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Erythrocytes; Female; Globins; Glycine; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Leucine; Macromolecular Substances; Models, Chemical; Peptides; Structure-Activity Relationship; Tritium; Valine | 1973 |
The site of hemoglobin synthesis in the avian erythrocyte.
Topics: Animals; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Columbidae; Cycloheximide; Erythrocytes; Heme; Hemoglobins; Isotope Labeling; Kinetics; Leucine; Membranes; Microscopy, Electron; Puromycin; Ribosomes; Saponins; Surface-Active Agents; Time Factors | 1973 |
Control of globin synthesis by hemin. Regulation by hemin of the formation and inactivation of a translational repressor of globin synthesis in rabbit reticulocyte lysates.
Topics: Animals; Apoproteins; Binding Sites; Carbon Radioisotopes; Cell-Free System; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cytosol; Genes, Regulator; Globins; Heme; Kinetics; Leucine; Myoglobin; Phenylhydrazines; Protein Binding; Protein Biosynthesis; Rabbits; Receptors, Drug; Reticulocytes; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation | 1974 |
Protein synthesis with rabbit reticulocyte preparations.
Topics: Anemia; Animals; Blood Proteins; Carbon Radioisotopes; Cell-Free System; Drug Stability; Evaluation Studies as Topic; Female; Heme; Hemoglobins; Leucine; Methods; Phenylhydrazines; Protein Biosynthesis; Rabbits; Reticulocytes; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Three-dimensional structure of hemoglobin from the polychaete annelid, Glycera dibranchiata, at 2.5 A resolution.
Topics: Amino Acids; Animals; Annelida; Computers; Crystallization; Crystallography; Electrons; Fourier Analysis; Heme; Hemoglobins; Histidine; Leucine; Models, Structural; Molecular Conformation; Protein Conformation; X-Ray Diffraction | 1974 |
Studies on the roles of synthesis and degradation in the control of enzyme levels in animal tissues.
Topics: Animals; Arginase; Cortisone; Heme; Homeostasis; Hydrocortisone; Immunodiffusion; Leucine; Liver; Lysine; Oxygenases; Rats; Transaminases; Tryptophan; Tryptophan Oxygenase; Ultracentrifugation | 1966 |
Intermediates in the biosynthesis of peroxisomal catalase in rat liver.
Topics: Animals; Catalase; Heme; Immunochemistry; Immunodiffusion; Leucine; Levulinic Acids; Methods; Microsomes, Liver; Rats; Tritium | 1971 |
The control of hemoglobin synthesis. A comparison of the role of heme in rabbit bone marrow and reticulocytes.
Topics: Acetates; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography, Gel; Globins; Heme; Hemoglobins; Kinetics; Leucine; Macromolecular Substances; Phenylhydrazines; Rabbits; Reticulocytes | 1972 |
Effects of phenobarbital, 3-methylcholanthrene, and hematin on the synthesis of protein components of rat liver microsomal membranes.
Topics: Animals; Carbon Isotopes; Cytochromes; Electrophoresis; Endoplasmic Reticulum; Heme; Leucine; Male; Membranes; Metabolism; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Phenobarbital; Rats; Sodium Dodecyl Sulfate; Solubility; Tritium | 1972 |
Porphyrin synthesis by cultured lymphocytes.
Topics: 5-Aminolevulinate Synthetase; Carbon Isotopes; Cells, Cultured; Enzyme Induction; Erythropoietin; Fluorometry; Heme; Humans; Ketosteroids; Lectins; Leucine; Levulinic Acids; Lymphocyte Activation; Lymphocytes; Microscopy, Fluorescence; Porphyrins; Pregnenolone | 1972 |
Hemin control of globin synthesis: action of an inhibitor formed in the absence of hemin on the reticulocyte cell-free system and its reversal by a ribosomal factor.
Topics: Animals; Blood Proteins; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Globins; Heme; Histidine; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; Trypsin | 1972 |
Decrease in hepatic cytochrome P-450 and catalase following allylisopropyl acetamide: the effect of concomitant hemin administration.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allyl Compounds; Amides; Animals; Ascorbic Acid; Carbon Isotopes; Catalase; Enzyme Induction; Heme; Leucine; Liver; Microsomes, Liver; Orotic Acid; Protein Biosynthesis; Rats; RNA; Tritium; Urate Oxidase | 1972 |
Synthesis, assembly, and localization of periplasmic cytochrome c.
Topics: Bacterial Proteins; Carbon Isotopes; Chloramphenicol; Culture Media; Cytochromes; Cytoplasm; Electrophoresis, Disc; Heme; Iron; Iron Isotopes; Kinetics; Leucine; Levulinic Acids; Pigments, Biological; Protein Binding; RNA, Bacterial; Spirillum; Tritium | 1972 |
Haemoglobin biosynthesis during in vitro maturation of the rat reticulocyte.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Globins; Heme; Hemoglobins; In Vitro Techniques; Iron; Iron Isotopes; Leucine; Male; Polyribosomes; Rats; Reticulocytes; Ribonucleases; Ribosomes; RNA; Time Factors | 1972 |
Hemin control of globin synthesis: an assay for the inhibitor formed in the absence of hemin and some characteristics of its formation.
Topics: Animals; Blood Proteins; Depression, Chemical; Globins; Heme; Hemoglobins; Hot Temperature; In Vitro Techniques; Leucine; Peptide Biosynthesis; Rabbits; Reticulocytes | 1971 |
Ligand binding in hemoglobin J Capetown.
Topics: Binding Sites; Carbon Monoxide; Glutamine; Haptoglobins; Heme; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Biology; Oxygen; Sulfur | 1971 |
The cell-free synthesis of cytochrome c by a microsomal fraction from rat liver.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Fractionation; Cell-Free System; Cytochromes; Enzyme Precursors; Female; Freezing; Heme; Hepatectomy; In Vitro Techniques; Iron; Iron Isotopes; Leucine; Levulinic Acids; Liver Regeneration; Magnesium; Male; Microsomes, Liver; Rats; Ribosomes; Tritium | 1971 |
Intermediates of hemoglobin and their relation to biosynthesis.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Electrophoresis, Disc; Globins; Heme; Hemoglobins; Humans; Iron Isotopes; Leucine; Oxidation-Reduction; Peptide Biosynthesis; Puromycin; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Tritium; Ultracentrifugation; Valine | 1971 |
Translational control in hemoglobin syntheskis.
Topics: Animals; Blood Proteins; Cell-Free System; Depression, Chemical; Deuterium; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Iron Isotopes; Isoleucine; Leucine; Liver; Metabolism; Models, Biological; Models, Structural; Peptide Biosynthesis; Porphyrins; Pyridines; Rabbits; Reticulocytes; Ribosomes; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Spectrophotometry; Stimulation, Chemical; Temperature; Threonine; Ultraviolet Rays | 1969 |
Translational control of in vitro hemoglobin synthesis.
Topics: Animals; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Globins; Heme; Hemoglobins; Kinetics; Leucine; Liver; Peptides; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer; Tritium; Valine | 1969 |
Alpha- and beta- peptide chain synthesis in sideroblastic anaemia.
Topics: Amino Acids; Anemia, Sideroblastic; Heme; Hemoglobins; Humans; In Vitro Techniques; Leucine; Levulinic Acids; Peptide Biosynthesis; Pyridoxal Phosphate; Reticulocytes; Tritium | 1969 |
Separation of haem incorporation from protein synthesis in liver microsomes.
Topics: Animals; Carbon Isotopes; Cycloheximide; Cytochromes; Heme; Leucine; Levulinic Acids; Microsomes, Liver; Protein Biosynthesis; Rats | 1969 |
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes.
Topics: Adjuvants, Anesthesia; Aniline Compounds; Animals; Anisoles; Blood Proteins; Body Weight; Carbon Disulfide; Carbon Isotopes; Cycloheximide; Cytochromes; DNA; Fasting; Heme; Injections, Intraperitoneal; Leucine; Lipids; Liver; Liver Glycogen; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organ Size; Phenobarbital; Proadifen; Protein Biosynthesis; Proteins; Rats; RNA; Spectrophotometry; Sucrose; Time Factors | 1969 |
Molecular weight and quaternary structure of yeast L-lactate dehydrogenase (cytochrome b2). 1. Minimum molecular weight from amino acid analyses.
Topics: Amino Acids; Autoanalysis; Chemical Phenomena; Chemistry; Cytochromes; Heme; L-Lactate Dehydrogenase; Leucine; Molecular Weight; Saccharomyces; Spectrum Analysis | 1970 |
Stimulation of globin synthesis: relative responsiveness of reticulocytes and nucleated erythroid cells.
Topics: Animals; Blood; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Nucleus; Chromatography; Cobalt; Heme; Hemoglobins; Iron; Leucine; Phenylhydrazines; Protein Binding; Pyruvates; Rabbits; Reticulocytes; Transferrin | 1970 |
Distribution of radioactive hemoprotein and CO-binding pigment in rough and smooth endoplasmic reticulum of rat liver.
Topics: Amino Acids; Animals; Carbon Monoxide; Cytochromes; Endoplasmic Reticulum; Heme; Kinetics; Leucine; Levulinic Acids; Liver; Male; Microsomes, Liver; Pigments, Biological; Protein Biosynthesis; Rats; Tritium | 1970 |
Haem a, cytochrome c and total protein turnover in mitochondria from rat heart and liver.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cytochromes; Female; Heme; Leucine; Levulinic Acids; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Proteins; Rats; Tritium | 1970 |
Studies on cessation of protein synthesis in a reticulocyte lysate cell-free system.
Topics: Animals; Carbon Isotopes; Cell-Free System; Globins; Heme; Kinetics; Leucine; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger | 1970 |
Turnover of heme and protein moieties of rat liver microsomal cytochrome b5.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cycloheximide; Cytochromes; Depression, Chemical; Guanidines; Half-Life; Heme; Kinetics; Leucine; Levulinic Acids; Male; Microsomes, Liver; Protein Biosynthesis; Proteins; Rats; Tritium | 1970 |
The stimulation of hemoglobin synthesis by porphyrins.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Cobalt; Copper; Depression, Chemical; Deuterium; Drug Antagonism; Erythrocytes; Globins; Heme; Hemoglobins; Iron; Lead; Leucine; Mercury; Nickel; Organometallic Compounds; Porphyrins; Stimulation, Chemical; Tin | 1970 |
Globin synthesis in sideroblastic anaemia. I. Alpha and beta peptide chain synthesis.
Topics: Adolescent; Adult; Aged; Anemia, Sideroblastic; Blood Proteins; Child; Chromatography; Female; Globins; Heme; Hemoglobins; Humans; In Vitro Techniques; Leucine; Male; Middle Aged; Peptide Biosynthesis; Reticulocytes; Tritium | 1971 |
Interaction of globin and heme during hemoglobin biosynthesis.
Topics: Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Paper; Detergents; Globins; Heme; Hemoglobins; Leucine; Levulinic Acids; Male; Porphyrins; Rabbits; Reticulocytes; Ribosomes; Tritium | 1968 |
Hemoglobin Gun Hill: an unstable protein associated with chronic hemolysis.
Topics: Adult; Blood Cell Count; Blood Protein Electrophoresis; Carbon Isotopes; Child; Chromium Isotopes; Feces; Female; Hematocrit; Heme; Hemoglobinometry; Hemoglobins, Abnormal; Humans; Iron Isotopes; Jaundice; Leucine; Male; Nitrogen; Pyrroles; Reticulocytes; Urobilinogen; White People | 1968 |
Excess of alpha-globin synthesis in homozygous beta-thalassemia. Its cytoplasmic molecular forms.
Topics: Adult; Blood Proteins; Centrifugation, Density Gradient; Child; Child, Preschool; Chromatography, Ion Exchange; Cytoplasm; Erythrocytes; Globins; Heme; Hemoglobins; Hemolysis; Homozygote; Humans; Infant, Newborn; Infant, Premature; Leucine; Lysine; Peptides; Thalassemia; Tritium; Valine | 1968 |
Effect of oxygen deficiency on cytochrome c, heme a, and iron protoporphyrin of L-cells.
Topics: Animals; Carbon Isotopes; Cell Division; Culture Techniques; Cytochromes; Fibroblasts; Heme; Hemoglobins; Iron; L Cells; Leucine; Mice; Oxidation-Reduction; Porphyrins; Protein Biosynthesis; Protein Denaturation | 1968 |
The inhibition of heme and globin synthesis by cobalt in rabbit reticulocytes and bone marrow.
Topics: Amino Acids; Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography, Gel; Cobalt; Globins; Glycine; Heme; Hemoglobins; In Vitro Techniques; Kinetics; Leucine; Levulinic Acids; Peptide Biosynthesis; Rabbits; Reticulocytes; Valine | 1968 |
Hemoglobin sabine beta 91 (F 7) leu → pro. An unstable variant causing severe anemia with inclusion bodies.
Topics: Adolescent; Amino Acid Sequence; Anemia, Hemolytic; Blood Protein Electrophoresis; Chromatography; Chromium Isotopes; Erythrocyte Aging; Erythrocyte Count; Erythrocytes; Female; Fetal Hemoglobin; Globins; Heinz Bodies; Heme; Hemoglobinometry; Hemoglobins, Abnormal; Hemolysin Proteins; Histocytochemistry; Humans; Leucine; Methemoglobin; Microscopy, Fluorescence; Proline; Protein Binding; Reticulocytes; Splenectomy | 1969 |
New unstable haemoglobin borås: beta 88 (F4) leucine-arginine.
Topics: Amino Acid Sequence; Arginine; Electrophoresis; Heme; Hemoglobins, Abnormal; Leucine; Mutation; Peptides; Trypsin | 1969 |
Inhibition of the biosynthetic completion of rabbit hemoglobin by isolated human hemoglobin chains.
Topics: Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Depression, Chemical; Electrophoresis; Heme; Hemoglobins; Humans; Leucine; Methods; Peptide Biosynthesis; Peptides; Rabbits; Reticulocytes; Ribosomes; Solubility; Species Specificity; Valine | 1969 |
Unequal synthesis of complementary globin chains of human fetal hemoglobin by the effect of L-O-methylthreonine.
Topics: Blood Proteins; Carbon Isotopes; Chromatography, Gel; Complement System Proteins; Depression, Chemical; Erythroblastosis, Fetal; Female; Fetal Hemoglobin; Globins; Heme; Hemolysis; Humans; In Vitro Techniques; Infant, Newborn; Isoleucine; Leucine; Lysine; Peptide Biosynthesis; Pregnancy; Solubility; Thalassemia; Threonine | 1969 |
Effect of protoporphyrin on hemoglobin synthesis.
Topics: Animals; Heme; Hemoglobins; In Vitro Techniques; Leucine; Porphyrins; Rabbits; Reticulocytes; Ribosomes | 1965 |
Control of hemoglobin synthesis by oxygen tension in a cell-free system.
Topics: Animals; Birds; Cell Nucleus; Chromatography; Erythrocytes; Globins; Heme; Hemoglobins; In Vitro Techniques; Iron; Leucine; Oxygen; Spectrophotometry | 1965 |
Heme stimulation of globin synthesis in a cell free system.
Topics: Animals; Birds; Blood Proteins; Carbon Isotopes; Cell Nucleus; Erythrocytes; Globins; Heme; In Vitro Techniques; Kinetics; Leucine; Oxygen; Radiometry | 1966 |
[The influence of puromycin on the morphogenesis and synthesis of the macromolecules in the chicken embryo].
Topics: Amino Acids; Animals; Autoradiography; Chick Embryo; Fetal Hemoglobin; Heme; In Vitro Techniques; Leucine; Macromolecular Substances; Nucleic Acids; Proteins; Puromycin; RNA; Tritium | 1966 |
The synthesis of globin dimers by a reticulocyte cell-free system.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Female; Globins; Heme; Hemoglobins; Leucine; Rabbits; Reticulocytes; Tritium | 1967 |
A possible biochemical basis for the use of hyperthermia in the treatment of cancer and virus infection.
Topics: Enzyme Activation; Fever; Heme; Hot Temperature; Humans; Interferons; Leucine; Neoplasms; Protein Biosynthesis; Protein Kinases | 1981 |
Synthesis of globin chains in the erythropoietic sites of the early chick embryo.
Topics: Animals; Benzidines; Blastoderm; Chick Embryo; Erythrocytes; Erythropoiesis; Fluorescent Antibody Technique; Globins; Heme; Hemoglobins; Leucine; Time Factors | 1983 |
Erythroid colony development as a function of age: the role of marrow cellular heme.
Topics: 5-Aminolevulinate Synthetase; Aging; Animals; Erythrocytes; Erythropoiesis; Glycine; Hematopoietic Stem Cells; Heme; Heme Oxygenase (Decyclizing); Leucine; Male; Porphobilinogen Synthase; Rats; Rats, Inbred Strains; Uridine | 1983 |
Modulation of bone marrow heme and protein synthesis by trace elements.
Topics: Animals; Bone Marrow; Gold; Heme; Heme Oxygenase (Decyclizing); Hemin; Iron; Leucine; Male; Manganese; Porphobilinogen Synthase; Protein Biosynthesis; Rats; Rats, Inbred Strains; Trace Elements | 1982 |
The decreased stimulatory activity of hemin for globin synthesis at high concentrations of potassium salts in a rabbit reticulocyte lysate system.
Topics: Animals; Dose-Response Relationship, Drug; Globins; Heme; Hemin; Leucine; Potassium; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer, Amino Acyl; RNA, Transfer, Met | 1981 |
Methionine-393 is an axial ligand of the heme b558 component of the cytochrome bd ubiquinol oxidase from Escherichia coli.
Topics: Amino Acid Sequence; Base Sequence; Cytochrome b Group; Cytochromes; Dithionite; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Genotype; Heme; Histidine; Leucine; Ligands; Macromolecular Substances; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADPH Oxidases; Oligodeoxyribonucleotides; Oxidation-Reduction; Oxidoreductases; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Restriction Mapping; Spectrophotometry | 1995 |
Replacements in a conserved leucine cluster in the hydrophobic heme pocket of cytochrome c.
Topics: Crystallography, X-Ray; Cytochrome c Group; Electron Transport; Heme; Leucine; Models, Molecular; Molecular Structure; Mutagenesis; Protein Conformation; Structure-Activity Relationship; Yeasts | 1995 |
Comparison of thermodynamic and kinetic effects between the Leu32-->norvaline and Leu35-->norvaline substitutions of the three-fragment complex of cytochrome c.
Topics: Amino Acid Sequence; Animals; Cytochrome c Group; Heme; Horses; In Vitro Techniques; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Spectrum Analysis; Thermodynamics; Valine | 1994 |
Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.
Topics: Adolescent; Adult; Aged; Amino Acids; Chromatography, High Pressure Liquid; Genetic Variation; Heme; Hemoglobins, Abnormal; Humans; Isoleucine; Leucine; Male; Mass Spectrometry; Middle Aged; Oxygen; Phenylalanine; Polycythemia | 1993 |
Cysteine proteinase inhibitors block early steps in hemoglobin degradation by cultured malaria parasites.
Topics: Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Heme; Hemoglobins; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Plasmodium falciparum; Protein Conformation; Protozoan Proteins; Vacuoles | 1996 |
Stimulation of tetrapyrrole synthesis in mammalian epithelial cells in culture by exposure to aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Cattle; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Epithelium; gamma-Aminobutyric Acid; Glutamic Acid; Heme; Kinetics; Leucine; Mammals; Pyrroles; Radioisotope Dilution Technique; Tetrapyrroles | 1997 |
Solubility of sickle hemoglobin measured by a kinetic micromethod.
Topics: Alanine; Carboxyhemoglobin; Heme; Hemoglobin A; Hemoglobin, Sickle; Humans; Kinetics; Leucine; Microchemistry; Models, Chemical; Photolysis; Point Mutation; Solubility; Thermodynamics | 1996 |
A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket.
Topics: Animals; Asparagine; Binding Sites; Circular Dichroism; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Horses; Leucine; Molecular Sequence Data; Mutation; Myocardium; Myoglobin; Nucleic Acid Conformation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectrophotometry | 1997 |
The effects of heme pocket hydrophobicity on the ligand binding dynamics in myoglobin as studied with leucine 29 mutants.
Topics: Amino Acid Substitution; Binding Sites; Carbon Monoxide; Heme; Humans; Leucine; Ligands; Myoglobin; Nuclear Magnetic Resonance, Biomolecular; Photolysis; Solubility; Spectrophotometry, Infrared; Structure-Activity Relationship | 1997 |
Functional implications of the proximal hydrogen-bonding network in myoglobin: a resonance Raman and kinetic study of Leu89, Ser92, His97, and F-helix swap mutants.
Topics: Animals; Heme; Histidine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Phenylalanine; Photolysis; Propionates; Protein Structure, Secondary; Spectrum Analysis, Raman; Whales | 1998 |
Proton NMR investigation of the heme active site structure of an engineered cytochrome c peroxidase that mimics manganese peroxidase.
Topics: Arginine; Aspartic Acid; Binding Sites; Cyanides; Cytochrome-c Peroxidase; Glutamic Acid; Glycine; Heme; Histidine; Leucine; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Peroxidases; Protein Engineering; Protons; Spectrophotometry; Valine | 1999 |
Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
Topics: Aspartic Acid; Circular Dichroism; Cysteine; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome-c Peroxidase; Cytochromes c; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Heme; Histidine; Imidazoles; Leucine; Ligands; Mutagenesis, Site-Directed; Protein Engineering; Spectrophotometry, Ultraviolet | 1999 |
Recombinant hemoglobin(alpha 29leucine --> phenylalanine, alpha 96valine --> tryptophan, beta 108asparagine --> lysine) exhibits low oxygen affinity and high cooperativity combined with resistance to autoxidation.
Topics: Amino Acid Substitution; Asparagine; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Humans; Kinetics; Leucine; Lysine; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Phenylalanine; Protein Binding; Recombinant Proteins; Tryptophan; Valine | 1999 |
Proximal and distal effects on the coordination chemistry of ferric Scapharca homodimeric hemoglobin as revealed by heme pocket mutants.
Topics: Amino Acid Substitution; Animals; Bivalvia; Dimerization; Ferric Compounds; Heme; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Leucine; Phenylalanine; Point Mutation; Spectrophotometry; Spectrum Analysis, Raman; Ultracentrifugation; Valine | 2000 |
Modulation of the activities of catalase-peroxidase HPI of Escherichia coli by site-directed mutagenesis.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalase; Catalysis; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Heme; Leucine; Mass Spectrometry; Mutagenesis, Site-Directed; Peroxidases; Phenylalanine; Recombinant Proteins; Substrate Specificity; Tryptophan | 2000 |
Functions of fluctuation in the heme-binding loops of cytochrome b5 revealed in the process of heme incorporation.
Topics: Animals; Carrier Proteins; Circular Dichroism; Cytochromes b5; Heme; Heme-Binding Proteins; Hemeproteins; Histidine; Kinetics; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Protein Structure, Secondary; Rats; Spectrophotometry, Ultraviolet; Spectrum Analysis; Structure-Activity Relationship | 2000 |
Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Binding Sites; Biopterins; Catalysis; Dimerization; Drosophila; Glutamine; Heme; Humans; Hydrogen Bonding; Leucine; Mice; Models, Molecular; Molecular Sequence Data; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Phenylalanine; Rats; Spectrophotometry, Atomic; Structure-Activity Relationship; Tryptophan | 2000 |
Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Heme; Humans; Isoleucine; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Phenylalanine; Protein Conformation; Recombinant Proteins; Thermodynamics; Valine | 2001 |
Water penetration and binding to ferric myoglobin.
Topics: Amino Acid Substitution; Animals; Binding Sites; Heme; Histidine; Horses; Hydrogen Bonding; Kinetics; Leucine; Ligands; Metmyoglobin; Models, Chemical; Nitric Oxide; Water | 2001 |
Mutants of the CuA site in cytochrome c oxidase of Rhodobacter sphaeroides: I. Spectral and functional properties.
Topics: Amino Acid Substitution; Asparagine; Cell Membrane; Copper; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glycine; Heme; Histidine; Iron; Kinetics; Leucine; Manganese; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Structure, Secondary; Proton Pumps; Rhodobacter sphaeroides; Spectrometry, Fluorescence; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 2002 |
Redox control in heme proteins: electrostatic substitution in the active site of leghemoglobin.
Topics: Aspartic Acid; Binding Sites; Circular Dichroism; Electrochemistry; Glycine max; Heme; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Leghemoglobin; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Time Factors | 2002 |
The carbon monoxide derivative of human hemoglobin carrying the double mutation LeuB10-->Tyr and HisE7-->Gln on alpha and beta chains probed by infrared spectroscopy.
Topics: Amino Acid Substitution; Carbon Monoxide; Carboxyhemoglobin; Glutamine; Heme; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Iron; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tyrosine | 2002 |
The role of the hydrophobic distal heme pocket of CooA in ligand sensing and response.
Topics: Bacterial Proteins; Cyanides; Dose-Response Relationship, Drug; Heme; Hemeproteins; Imidazoles; Isoleucine; Leucine; Ligands; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rhodospirillum rubrum; Trans-Activators; Transcriptional Activation | 2003 |
Temperature, pH, and solvent isotope dependent properties of the active sites of resting-state and cyanide-ligated recombinant cytochrome c peroxidase (H52L) revealed by proton hyperfine resonance spectra.
Topics: Amino Acid Substitution; Binding Sites; Cyanides; Cytochrome-c Peroxidase; Heme; Histidine; Hydrogen-Ion Concentration; Leucine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protons; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Solvents; Temperature | 2003 |
Horseradish peroxidase mutants that autocatalytically modify their prosthetic heme group: insights into mammalian peroxidase heme-protein covalent bonds.
Topics: Animals; Carboxylic Acids; Catalysis; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Genetic Variation; Glutamic Acid; Glycine; Heme; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Insecta; Kinetics; Leucine; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peroxidase; Phenylalanine; Porphyrins; Protein Structure, Secondary; Serine; Spectrophotometry; Time Factors; Ultraviolet Rays | 2004 |
Roles of noncoordinated aromatic residues in redox regulation of cytochrome c3 from Desulfovibrio vulgaris Miyazaki F.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Cytochrome c Group; Desulfovibrio vulgaris; Electrochemistry; Heme; Histidine; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenylalanine; Tyrosine | 2004 |
The C-helix in CooA rolls upon CO binding to ferrous heme.
Topics: Bacterial Proteins; Carbon Monoxide; Databases as Topic; Escherichia coli; Heme; Hemeproteins; Humans; Iron; Leucine; Ligands; Models, Biological; Models, Molecular; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodospirillum rubrum; Spectrum Analysis, Raman; Trans-Activators | 2004 |
Biophysical and kinetic characterization of HemAT, an aerotaxis receptor from Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Biophysics; Carbon Monoxide; Circular Dichroism; Heme; Hydrogen-Ion Concentration; Kinetics; Leucine; Ligands; Models, Molecular; Mutation; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Temperature; Time Factors; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 2005 |
Effects of metal ions in the CuB center on the redox properties of heme in heme-copper oxidases: spectroelectrochemical studies of an engineered heme-copper center in myoglobin.
Topics: Amine Oxidase (Copper-Containing); Animals; Cations, Divalent; Cattle; Copper; Electron Transport; Electron Transport Complex IV; Heme; Histidine; Leucine; Myoglobin; Oxidation-Reduction; Phenylalanine; Potentiometry; Protein Engineering; Spectrophotometry, Ultraviolet; Whales; Zinc | 2005 |
Redox-dependent structural changes in an engineered heme-copper center in myoglobin: insights into chloride binding to CuB in heme copper oxidases.
Topics: Amino Acid Substitution; Animals; Binding Sites; Copper; Electrolysis; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Histidine; Hydroxides; Leucine; Myoglobin; Oxidation-Reduction; Phenylalanine; Potassium Chloride; Potentiometry; Spectrophotometry, Ultraviolet; Whales | 2005 |
A biophysical investigation of recombinant hemoglobins with aromatic B10 mutations in the distal heme pockets.
Topics: Adult; Amino Acid Substitution; Azides; Heme; Hemoglobin A; Hemoglobins; Humans; Leucine; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Phenylalanine; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Thermodynamics; Tryptophan | 2005 |
Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a heme-regulated phosphodiesterase from Escherichia coli.
Topics: Amino Acid Sequence; Carbon Monoxide; Escherichia coli; Ferric Compounds; Ferrous Compounds; Heme; Heme Oxygenase-1; Hydrophobic and Hydrophilic Interactions; Iron; Leucine; Molecular Sequence Data; Molecular Structure; Mutation; Nitric Oxide; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Photolysis; Protein Binding | 2006 |
Glutamates 99 and 107 in transmembrane helix III of subunit I of cytochrome bd are critical for binding of the heme b595-d binuclear center and enzyme activity.
Topics: Aerobiosis; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Conserved Sequence; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Enzyme Activation; Escherichia coli Proteins; Glutamic Acid; Heme; Leucine; Membrane Proteins; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Oxygen; Oxygen Consumption; Protein Structure, Secondary; Protein Subunits; Ubiquinone | 2006 |
ATP-driven reduction by dark-operative protochlorophyllide oxidoreductase from Chlorobium tepidum mechanistically resembles nitrogenase catalysis.
Topics: Adenosine Triphosphate; Catalysis; Chlorobium; Cysteine; Dithionite; Electrons; Escherichia coli; Heme; Kinetics; Leucine; Light; Lysine; Nitrogenase; Oxidoreductases; Protochlorophyllide | 2008 |
Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
Topics: Bacterial Proteins; Crystallization; Crystallography, X-Ray; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids; Heme; Imidazoles; Leucine; Mixed Function Oxygenases; Models, Molecular; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Conformation | 2008 |
Glutamate 107 in subunit I of cytochrome bd from Escherichia coli is part of a transmembrane intraprotein pathway conducting protons from the cytoplasm to the heme b595/heme d active site.
Topics: Binding Sites; Carbon Monoxide; Cytochrome b Group; Cytochromes; Cytoplasm; Electrochemistry; Electron Transport Chain Complex Proteins; Escherichia coli Proteins; Glutamic Acid; Heme; Leucine; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Photolysis; Protein Binding; Protons | 2008 |
Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials.
Topics: Cytochromes b5; Electrochemistry; Electron Spin Resonance Spectroscopy; Electron Transport; Heme; Humans; Leucine; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Conformation | 2010 |
Leu65 in the heme distal side is critical for the stability of the Fe(II)-O2 complex of YddV, a globin-coupled oxygen sensor diguanylate cyclase.
Topics: Carbon Monoxide; Escherichia coli Proteins; Ferric Compounds; Heme; Leucine; Oxygen; Phosphorus-Oxygen Lyases | 2012 |
A distal pocket Leu residue inhibits the binding of O2 and NO at the distal heme site of cytochrome c'.
Topics: Alcaligenes; Binding Sites; Cytochromes c; Heme; Leucine; Nitric Oxide; Oxygen; Point Mutation | 2012 |
Modulation of ligand-heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond-second temporal range.
Topics: Arginine; Binding Sites; Crystallography, X-Ray; Cytochromes c; Heme; Humans; Kinetics; Leucine; Models, Chemical; Nitric Oxide; Photolysis; Protein Binding; Spectrophotometry, Infrared | 2013 |
Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reaction.
Topics: Carbon Monoxide; Escherichia coli Proteins; Heme; Heme Oxygenase (Decyclizing); Leucine; Mutation; Oxygen; Phosphorus-Oxygen Lyases; Water | 2014 |
Tryptophan-to-heme electron transfer in ferrous myoglobins.
Topics: Algorithms; Electron Transport; Ferric Compounds; Ferrous Compounds; Heme; Kinetics; Leucine; Models, Chemical; Models, Molecular; Myoglobin; Porphyrins; Protein Structure, Tertiary; Spectrophotometry; Tryptophan; Valine | 2015 |