heme has been researched along with flurbiprofen in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garavito, RM; Loll, PJ; Picot, D | 1 |
| Beechem, JM; Lanzo, CA; Marnett, LJ; Talley, J | 1 |
| Kulmacz, RJ; Osawa, Y; Tsai, AL; Vuletich, JL; Wu, G | 1 |
| Gupta, K; Katz, AK; Kaub, CJ; Loll, PJ; Selinsky, BS | 1 |
| Aguilar, JS; Gannett, PM; Hummel, MA; Tracy, TS | 1 |
| Jones, JP; Locuson, CW; Tracy, TS; Wienkers, LC | 1 |
| Dong, L; Jurban, BJ; Sharma, NP; Smith, WL | 1 |
7 other study(ies) available for heme and flurbiprofen
| Article | Year |
|---|---|
The 3.1 A X-ray crystal structure of the integral membrane enzyme prostaglandin H2 synthase-1.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Flurbiprofen; Heme; Isoenzymes; Membrane Proteins; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Protein Structure, Secondary; Sheep | 1995 |
Investigation of the binding of isoform-selective inhibitors to prostaglandin endoperoxide synthases using fluorescence spectroscopy.
Topics: Animals; Apoenzymes; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Energy Transfer; Fluorescence Polarization; Flurbiprofen; Heme; Humans; Isoenzymes; Kinetics; Membrane Proteins; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Protein Binding; Quantum Theory; Sheep; Spectrometry, Fluorescence; Thiazoles; Titrimetry | 1998 |
Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.
Topics: Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Flurbiprofen; Heme; Indomethacin; Isoenzymes; Kinetics; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Protoporphyrins; Spectrometry, Mass, Electrospray Ionization | 2001 |
The 2.0 A resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase.
Topics: Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Cyclooxygenase Inhibitors; Epidermal Growth Factor; Flurbiprofen; Glycerol; Heme; Histidine; Hydrogen Bonding; Isoenzymes; Lipid Bilayers; Male; Membrane Proteins; Models, Molecular; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Seminal Vesicles; Sheep | 2004 |
Effector-mediated alteration of substrate orientation in cytochrome P450 2C9.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Dapsone; Enzyme Activation; Flurbiprofen; Heme; Humans; Hydroxylation; Iron; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Protein Conformation; Substrate Specificity | 2004 |
CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis.
Topics: Allosteric Regulation; Animals; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Cytochromes b5; Diclofenac; Flurbiprofen; Heme; Humans; Hydrogen Peroxide; Kinetics; Models, Biological; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Conformation; Rats; Recombinant Proteins; Warfarin; Water | 2007 |
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides | 2013 |