heme has been researched along with dactinomycin in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (82.09) | 18.7374 |
| 1990's | 7 (10.45) | 18.2507 |
| 2000's | 4 (5.97) | 29.6817 |
| 2010's | 1 (1.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Badawy, AA | 1 |
| Maines, MD; Sinclair, P | 1 |
| Holbrook, DJ; Krasny, HC | 1 |
| Padmanaban, G; Rajamanickam, C; Rao, MR | 1 |
| Kappas, A; Maines, MD | 1 |
| Badawy, AA; Evans, M | 1 |
| Sassa, S | 1 |
| Israels, LG; Schacter, BA; Yoda, B | 1 |
| den Blaauwen, J; Mattia, E; van Renswoude, J | 1 |
| Kaliman, PA; Manandkhar, SP; Nikitchenko, IV | 1 |
| Chhabra, R; Datta, K; Singh, NK | 1 |
| Bonkovsky, HL; Healey, JF; Lincoln, BC | 1 |
| Munro, H; Rogers, J | 1 |
| Kuroiwa, Y; Numazawa, S; Oguro, T; Yoshida, T | 1 |
| Belovetskaia, IV; Kaliman, PA | 1 |
| Marks, GS; Racz, WJ; Schneck, DW; Tyrrell, DL | 1 |
| Granick, S; Sassa, S | 1 |
| Engel, P; Marver, HS; Pimstone, NR; Schmid, R; Seitz, PT; Tenhunen, R | 2 |
| Doss, M; Philipp-Dormston, WK | 2 |
| Hayashi, N; Kikuchi, G; Yoda, B | 2 |
| Hershko, C; Izak, G; Schwartz, R | 1 |
| Gardner, FH; Gorshein, D | 1 |
| Bottomley, SS; Moore, MA; Smithee, GA; Whitcomb, WH | 1 |
| Lockshin, RA; Soslau, G; Stotz, EH | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Marks, GS; Tyrrell, DL | 1 |
| Fudenberg, HH; Gemsa, C; Schmid, R; Woo, CH | 1 |
| Gayathri, AK; Padmanaban, G; Rao, MR | 1 |
| Malathi, K; Padmanaban, G; Rao, MR | 1 |
| Seifert, J | 1 |
| Nichol, AW | 1 |
| Goldwasser, E | 1 |
| Hokama, Y; Nishimura, ET; Scheller, C; Yamada, K | 1 |
| Manning, J; Marver, HS; Strand, LJ | 1 |
| Hayashi, N; Kikuchi, G; Kurashima, Y | 2 |
| Levere, RD; Mizoguchi, H | 1 |
| Marks, GS; Schneck, DW; Tyrrell, DL | 1 |
| Granick, S; Kappas, A | 1 |
| Nakao, K; Sassa, S; Takaku, F; Wada, O | 1 |
| Bausserman, LL; Nebert, DW | 1 |
| Tambourin, P; Wendling, F | 1 |
| Goldwasser, E; Hrinda, ME | 1 |
| Miura, Y; Mizoguchi, H; Nakao, K; Takaku, F | 1 |
| Kappas, A; Song, CS | 1 |
| Collins, A; Tschudy, DP; Waxman, AD | 1 |
| Sasa, S | 1 |
| Ward, HP | 1 |
| Berman, L; Powsner, E | 1 |
| Arnstein, HR; Bonanou-Tzedaki, SA; Sohi, MK | 1 |
| Ades, IZ; Harpe, KG; Stevens, TM | 1 |
| Gage, AT; Stanton, PK | 1 |
| Bonkovsky, HL; Cable, EE; Donohue, SE; Gildemeister, OS; Lambrecht, RW; Pepe, JA | 1 |
| Kottari, S; Pelkonen, O; Raunio, H; Salonpää, P | 1 |
| Battle, A; Fukuda, H; Riley, P; Washbrook, R | 1 |
| Immenschuh, S; Iwahara, S; Katz, N; Muller-Eberhard, U; Nell, C | 1 |
| Padmaja, K; Prasad, AR; Ramamurthi, R | 1 |
| Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T; Ziemann, C | 1 |
| Fujita, H; Furuyama, K; Hattori, T; Hida, W; Igarashi, K; Kitamuro, T; Nakayama, M; Ogawa, K; Shibahara, S; Shirato, K; Sun, J; Takahashi, K; Takeda, K; Udono-Fujimori, R | 1 |
| GREENGARD, O | 1 |
| FUNAHASHI, S; SHICHI, H; SUGIMURA, Y | 1 |
| Llewellyn, DH; Redding, SJ; Roberts, AG | 1 |
| Bonkovsky, HL; Donohue, SE; Lambrecht, RW; Shan, Y; Zheng, J | 1 |
| Colgan, SP; Onyiah, JC; Schaefer, REM | 1 |
2 review(s) available for heme and dactinomycin
| Article | Year |
|---|---|
The functions and regulation of tryptophan pyrrolase.
Topics: Allosteric Regulation; Aminolevulinic Acid; Animals; Dactinomycin; Feedback; Gluconeogenesis; Heme; Kinetics; Kynurenine; Liver; NAD; NADP; Rats; Tryptophan; Tryptophan Oxygenase | 1977 |
Biochemical control of erythroid cell development.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Differentiation; Cobalt; Dactinomycin; Erythropoiesis; Erythropoietin; Genes, Regulator; Glucosamine; Glycols; Hematopoietic Stem Cells; Heme; Hemoglobins; In Vitro Techniques; Models, Biological; Pituitary Gland; Rats; Reticulocytes; RNA; Steroids; Thyroid Hormones | 1966 |
65 other study(ies) available for heme and dactinomycin
| Article | Year |
|---|---|
Cobalt regulation of heme synthesis and degradation in avian embryo liver cell culture.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cobalt; Cycloheximide; Dactinomycin; Enzyme Induction; Heme; Iron; Liver; Maleates; Mixed Function Oxygenases | 1977 |
Effects of cadmium on heme oxygenase and hemoproteins in smooth and rough endoplasmic reticulum of rat liver.
Topics: Animals; Cadmium; Cycloheximide; Dactinomycin; Endoplasmic Reticulum; Heme; Hemeproteins; Liver; Male; Mixed Function Oxygenases; Rats; RNA; Time Factors | 1978 |
On the sequence of reactions leading to cytochrome P-450 synthesis-effect of drugs.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Apoproteins; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Endoplasmic Reticulum; Glycine; Heme; Iron; Liver; Male; Microsomes, Liver; Phenobarbital; Rats | 1975 |
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Bilirubin; Cobalt; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dactinomycin; Ethylmorphine-N-Demethylase; Heme; Iodides; Liver; Microsomes, Liver; Oxygen Consumption; Porphyrins; Puromycin; Rats; Thiocyanates; Time Factors; Triazoles; Urea | 1975 |
Regulation of rat liver tryptophan pyrrolase by its cofactor haem: Experiments with haematin and 5-aminolaevulinate and comparison with the substrate and hormonal mechanisms.
Topics: Aminolevulinic Acid; Apoenzymes; Cycloheximide; Dactinomycin; Hematinics; Heme; Hydrocortisone; Liver; Porphyrias; Porphyrinogens; Puromycin; Tryptophan; Tryptophan Oxygenase | 1975 |
Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Bromodeoxyuridine; Cell Transformation, Neoplastic; Cells, Cultured; Dactinomycin; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Induction; Erythrocytes; Friend murine leukemia virus; Genes; Heme; Hydro-Lyases; Hydroxymethylbilane Synthase; Leukemia, Experimental; Lyases; Mice; Porphobilinogen Synthase; RNA, Neoplasm; Thymidine | 1976 |
Cyclic oscillations in rat hepatic heme oxygenase and delta-aminolevulinic acid synthetase following intravenous heme administration.
Topics: 5-Aminolevulinate Synthetase; Albumins; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Female; Heme; Liver; Microsomes, Liver; Oxygenases; Rats | 1976 |
Role of protein synthesis in the accumulation of ferritin mRNA during exposure of cells to iron.
Topics: Cell Line; Cycloheximide; Dactinomycin; Ferritins; Heme; Humans; Iron; Kinetics; Pactamycin; Polyribosomes; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger; Transcription, Genetic | 1990 |
[The role of heme in the regulation of tryptophan-2,3-dioxygenase activity and content of cytochrome P-450 in rat liver].
Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Drug Interactions; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Tryptophan Oxygenase | 1989 |
Induction of L-alanine:4,5-dioxovalerate transaminase by phenylhydrazine is associated with depletion of heme level.
Topics: Anemia; Animals; Cobalt; Dactinomycin; Erythropoietin; Hematocrit; Heme; Immune Sera; Immunodiffusion; Kidney; Kinetics; Liver; Male; Phenylhydrazines; Rats; Rats, Inbred Strains; Transaminases | 1986 |
Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Glutethimide; Heme; Heme Oxygenase (Decyclizing); Liver; Mephenytoin; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Porphyrins | 1988 |
Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.
Topics: Animals; Cell Line; Dactinomycin; Deferoxamine; DNA; Ferritins; Heme; Iron; Liver Neoplasms, Experimental; Macromolecular Substances; Polyribosomes; Protein Biosynthesis; Rats; RNA, Messenger | 1987 |
Effects of phorone (diisopropylidene acetone), a glutathione (GSH) depletor, on hepatic enzymes involved in drug and heme metabolism in rats: evidence that phorone is a potent inducer of heme oxygenase.
Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Glutathione; Heme; Heme Oxygenase (Decyclizing); Ketones; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Solvents | 1987 |
[Effect of cobalt chloride on the activity of key enzymes of heme metabolism in the rat liver].
Topics: 5-Aminolevulinate Synthetase; Animals; Cobalt; Cycloheximide; Dactinomycin; Enzyme Activation; Heme; Heme Oxygenase (Decyclizing); Kinetics; Liver; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1986 |
Pharmacogenetics and porphyria.
Topics: Acetamides; Amides; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Esters; Heme; Liver; Pharmacogenetics; Porphyrias; Porphyrins; Pyridines | 1971 |
Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acyltransferases; Allyl Compounds; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Depression, Chemical; Enzyme Induction; Etiocholanolone; Half-Life; Heme; Hexachlorocyclohexane; Leucine; Liver; Orotic Acid; Pyridones; RNA, Messenger; Time Factors | 1970 |
Further studies of microsomal haem oxygenase: mechanism for stimulation of enzyme activity and cellular localization.
Topics: Albumins; Animals; Bile Pigments; Bilirubin; Chemical Phenomena; Chemistry; Cycloheximide; Dactinomycin; Enzyme Activation; Heme; Hemoglobins; Kidney; Liver; Macrophages; Microsomes; Mononuclear Phagocyte System; Oxygenases; Puromycin; Rats; Spleen; Zymosan | 1971 |
The effect of DL-lactate on regulation of porphyrin and heme biosynthesis in Escherichia coli and Achromobacter.
Topics: Alcaligenes; Chromatography, Thin Layer; Copper; Dactinomycin; Escherichia coli; Heme; L-Lactate Dehydrogenase; Lactates; Porphyrins; Puromycin; Species Specificity; Time Factors; Ultrasonics | 1974 |
Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. II. Effects of hemin and bilirubin on enzyme induction.
Topics: Amides; Animals; Bilirubin; Dactinomycin; Depression, Chemical; Electron Transport Complex IV; Enzyme Induction; Glucose-6-Phosphatase; Heme; Hydro-Lyases; Levulinic Acids; Ligases; Male; Mitochondria, Liver; Rats | 1968 |
Morphological-biochemical correlations in rabbit red cell precursors synchronized by actinomycin administration.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Division; Dactinomycin; DNA; Erythrocytes; Erythropoiesis; Glycine; Heme; In Vitro Techniques; Iron Isotopes; Phosphorus Isotopes; Protein Biosynthesis; Rabbits; RNA | 1969 |
Regulation of erythropoiesis by androgens.
Topics: Androgens; Anemia; Animals; Bone Marrow; Chick Embryo; Dactinomycin; Erythropoiesis; Erythropoietin; Haplorhini; Heme; Hemoglobins; Humans; Hypoxia; Iron Isotopes; Mice; Oxygen; Stimulation, Chemical; Testosterone; Time Factors | 1973 |
Regulatory link between lactate dehydrogenase and biosynthesis of porphyrin and heme in microorganisms.
Topics: Alcaligenes; Cell-Free System; Chromatography, Thin Layer; Culture Media; Dactinomycin; Escherichia coli; Heme; Kinetics; L-Lactate Dehydrogenase; Lactates; Levulinic Acids; Porphyrins; Pseudomonas aeruginosa; Puromycin; Species Specificity; Spectrophotometry; Time Factors | 1973 |
Effect of cyclic adenosine-3',5'-monophosphate on bone marrow delta-aminolevulinic acid synthetase and erythrocyte iron uptake.
Topics: Acyltransferases; Adenine Nucleotides; Amino Acids; Animals; Bone Marrow; Bone Marrow Cells; Culture Techniques; Cyclic AMP; Cycloheximide; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Iron; Iron Isotopes; Levulinic Acids; Mice; Mitochondria; Rabbits; Stimulation, Chemical; Succinates; Theophylline | 1971 |
Stimulation of cytochrome c synthesis in the developing Polyphemus moth by -aminolevulinic acid.
Topics: Animals; Bombyx; Chloramphenicol; Cytochromes; Dactinomycin; Drug Stability; Electron Transport Complex IV; Female; Heme; Levulinic Acids; Mitochondria, Muscle; Puromycin; RNA, Messenger; Spectrophotometry | 1971 |
Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism.
Topics: Adaptation, Physiological; Animals; Bilirubin; Bone Marrow; Cycloheximide; Dactinomycin; Disease Models, Animal; Enzyme Induction; Female; Heme; Hemoglobins; Hemoglobinuria; Homeostasis; Injections, Intravenous; Iron Isotopes; Kidney Tubules; Liver; NADP; Oxygenases; Protein Biosynthesis; Puromycin; Rats; RNA; Spleen | 1971 |
Regulation of onset of rapid hemoglobin formation in chick blastodisc blood islands at the transcription and translation levels. A quantitative analysis of effects of actinomycin, ethanol, and heme precursors.
Topics: Animals; Chick Embryo; Culture Media; Dactinomycin; Ethanol; Female; Heme; Hemoglobins; Leucine; Levulinic Acids; Ovum; Porphyrins; Protein Biosynthesis; Protein Precursors; Stimulation, Chemical; Time Factors; Transcription, Genetic; Tritium; Uridine | 1972 |
Drug-induced porphyrin biosynthesis. V. Effect of protohemin on the transcriptional and post-transcriptional phases of -aminolevulinic acid synthetase induction.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Dicarboxylic Acids; Enzyme Induction; Heme; Liver; Porphyrins; Pyridines; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium; Uridine | 1972 |
Erythrocyte catabolism by macrophages in vitro. The effect of hydrocortisone on erythrophagocytosis and on the induction of heme oxygenase.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Dactinomycin; Enzyme Induction; Erythrocytes; Female; Glucose; Heme; Hydrocortisone; Insulin; Iron Isotopes; Macrophages; Oxygenases; Phagocytosis; Pinocytosis; Puromycin; Rabbits; Rats | 1973 |
Studies on the induction of -aminolevulinic acid synthetase iun mouse liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Cycloheximide; Cytosol; Dactinomycin; Dicarboxylic Acids; Enzyme Induction; Female; Half-Life; Heme; Kinetics; Liver; Mice; Mitochondria, Liver; Molecular Weight; Pyridines; Spectrophotometry; Starvation; Subcellular Fractions; Time Factors | 1973 |
A model for the regulation of delta-aminolaevulinate synthetase induction in rat liver.
Topics: 5-Aminolevulinate Synthetase; Adrenalectomy; Allylisopropylacetamide; Animals; Carbon Radioisotopes; Castration; Citrates; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Female; Heme; Hydrocortisone; Iron Radioisotopes; Liver; Male; Microsomes, Liver; Models, Biological; Phenobarbital; Protein Binding; Rats | 1973 |
Tryptophan pyrrolase in rat liver after phenobarbital administration.
Topics: Animals; Ascorbic Acid; Dactinomycin; Enzyme Activation; Enzyme Induction; Heme; Hydrocortisone; Liver; Male; Phenobarbital; Proteins; Rats; Time Factors; Tryptophan; Tryptophan Oxygenase | 1973 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Relationship of Cx-reactive protein response to induction of liver and kidney catalases following hematin administration into rabbits.
Topics: Animals; Anti-Bacterial Agents; Blood Proteins; C-Reactive Protein; Catalase; Culture Techniques; Dactinomycin; Enzyme Induction; Freund's Adjuvant; Heme; Immunodiffusion; Immunoelectrophoresis; Injections, Intravenous; Kidney; Liver; Naphthacenes; Peroxidases; Puromycin; Rabbits | 1970 |
The induction of -aminolevulinic acid synthetase in cultured liver cells. The effects of end product and inhibitors of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetates; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Repression; Heme; Humans; Iron; Iron Isotopes; Kinetics; Lead; Levulinic Acids; Liver; Porphyrias; Succinates; Tritium | 1972 |
Mechanism of allylisopropylacetamide-induced increase of -aminolevulinate synthetase in liver mitochondria. V. Mechanism of regulation by hemin of the level of -aminolevulinate synthetase in rat liver mitochondria.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acyltransferases; Allyl Compounds; Animals; Bilirubin; Cycloheximide; Dactinomycin; Enzyme Induction; Heme; Hydrocortisone; Kinetics; Liver; Male; Mitochondria, Liver; Rats; Subcellular Fractions | 1972 |
Enhancement of heme and globin synthesis in cultured human marrow by certain 5 -H steroid metabolites.
Topics: 5-Aminolevulinate Synthetase; Bile Acids and Salts; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cells, Cultured; Chromatography; Dactinomycin; Enzyme Induction; Erythropoiesis; Erythropoietin; Etiocholanolone; Globins; Heme; Hemoglobins; Humans; In Vitro Techniques; Iron; Iron Isotopes; Ketones; Ketosteroids; Methylcellulose; Pregnanediol; Pregnanes; Progesterone; Puromycin; Stimulation, Chemical; Testosterone; Valine | 1971 |
Drug-induced porphyrin biosynthesis. 3. Inhibition of drug-induced porphyria by protohemin.
Topics: Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Depression, Chemical; Glutarates; Glutethimide; Griseofulvin; Heme; Liver; Phthalic Acids; Porphyrias; Porphyrins; Pyridines | 1971 |
Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites.
Topics: Animals; Chick Embryo; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Repression; Etiocholanolone; Glucuronates; Heme; Liver; Mitomycins; Porphyrins; Puromycin; Steroids; Uracil Nucleotides | 1967 |
Enzymatic studies on erythroid differentiation and proliferation.
Topics: Animals; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Hydro-Lyases; Iron; Iron Isotopes; Ligases; Mice; Spleen | 1968 |
Aryl hydrocarbon hydroxylase induction in cell culture as a function of gene expression.
Topics: Aging; Animals; Animals, Newborn; Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Cell Line; Cricetinae; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Female; Fetus; Fluorometry; Gestational Age; Half-Life; Heme; Kinetics; Liver; Mice; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Molecular Biology; Pregnancy; Spectrophotometry; Tritium | 1971 |
Malignant transformation and erythroid differentiation by polycythaemia-inducing Friend virus.
Topics: Animals; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dactinomycin; Erythrocytes, Abnormal; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Heme; Hemoglobins; Iron Isotopes; Mice; Mice, Inbred Strains; Polycythemia; Reticulocytes; Spleen; Virus Replication | 1971 |
On the mechanism of erythropoietin-induced differentiation. VI. Induced accumulation of iron by marrow cells.
Topics: Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Cattle; Cell Differentiation; Chromatography, Gel; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Depression, Chemical; Erythropoiesis; Erythropoietin; Femur; Ferritins; Heme; Iron; Iron Isotopes; Male; Metabolism; Puromycin; Rats; RNA; Sheep; Stimulation, Chemical; Tibia; Time Factors; Transferrin | 1969 |
Mechanism of inhibition by hemin of increase of delta-aminolevulinate synthetase in liver mitochondria.
Topics: Acetates; Animals; Cycloheximide; Dactinomycin; Heme; In Vitro Techniques; Levulinic Acids; Ligases; Male; Mitochondria, Liver; Rats | 1970 |
In vitro effect of erythropoietin on the spleen of the polycythemic mouse. 3. Limited exposure to erythropoietin and actinomycin D.
Topics: Animals; Blood Cell Count; Culture Techniques; Dactinomycin; Erythropoietin; Heme; Iron Isotopes; Mice; Polycythemia; Reticulocytes; Spleen; Time Factors | 1968 |
Enzyme induction in the liver.
Topics: Cycloheximide; Dactinomycin; Enzyme Induction; Glucuronates; Heme; Humans; Liver; Microsomes; Mitomycins; Nucleic Acids; Porphyrins; Protein Biosynthesis; Puromycin; Ribosomes | 1968 |
Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. IV. Accumulation of the enzyme in the soluble fraction of rat liver.
Topics: Acyltransferases; Amides; Amino Acids; Animals; Bilirubin; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Stability; Enzyme Induction; Heme; Kinetics; Levulinic Acids; Liver; Male; Microsomes; Mitochondria, Liver; Mitomycins; Rats; Solubility; Stimulation, Chemical; Temperature | 1969 |
Oscillations of hepatic delta-aminolevulinic acid synthetase produced in vivo by heme.
Topics: Animals; Biological Clocks; Dactinomycin; Enzyme Repression; Heme; Hypnotics and Sedatives; Levulinic Acids; Ligases; Liver; Rats | 1966 |
[Studies on the mechanism of the action of erythropoietin with emphasis on stem cell differentiation].
Topics: Amino Acids; Animals; Cell Differentiation; Dactinomycin; Erythrocytes; Erythropoietin; Female; Globins; Heme; Hydro-Lyases; Iron Isotopes; Levulinic Acids; Ligases; Mice; Polycythemia; Spleen | 1966 |
An in vitro assay of erythropoietin.
Topics: Animals; Antibodies; Biological Assay; Bone Marrow Cells; Culture Techniques; Dactinomycin; Dogs; Erythropoietin; Heme; Iron; Iron Isotopes; Trypsin | 1967 |
Erythropoietin-induced DNA synthesis in normoblasts in vitro: effect of Actinomycin-D.
Topics: Dactinomycin; DNA; Erythrocytes; Erythropoietin; Heme; In Vitro Techniques; Iron Isotopes; Thymidine; Tritium | 1967 |
The effect of haemin on RNA synthesis and stability in differentiating rabbit erythroblasts.
Topics: Animals; Bone Marrow; Cell Differentiation; Cells, Cultured; Dactinomycin; Erythroblasts; Globins; Heme; Hemin; Poly A; Protein Biosynthesis; Rabbits; RNA; RNA, Messenger | 1984 |
Biogenesis of mitochondrial proteins. Regulation of production of delta-aminolaevulinate synthase by haemin in embryonic-chick liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Heme; Hemin; Immunoassay; In Vitro Techniques; Liver | 1983 |
Hypoxia triggers neuroprotective alterations in hippocampal gene expression via a heme-containing sensor.
Topics: Adaptation, Physiological; Animals; Biosensing Techniques; Cycloheximide; Dactinomycin; Excitatory Amino Acid Agonists; Gene Expression Regulation; Heme; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Dactinomycin; Deferoxamine; Enzyme Inhibitors; Glutethimide; Heme; Heptanoates; Kinetics; Liver; Metalloporphyrins; Porphobilinogen Synthase; Regression Analysis; RNA, Messenger | 1996 |
Regulation of CYP 2 A 5 induction by porphyrinogenic agents in mouse primary hepatocytes.
Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Griseofulvin; Heme; Liver; Male; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Nitrobenzoates; Phenobarbital; RNA, Messenger | 1997 |
Stimulation of tetrapyrrole synthesis in mammalian epithelial cells in culture by exposure to aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Cattle; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Epithelium; gamma-Aminobutyric Acid; Glutamic Acid; Heme; Kinetics; Leucine; Mammals; Pyrroles; Radioisotope Dilution Technique; Tetrapyrroles | 1997 |
Gene regulation of HBP 23 by metalloporphyrins and protoporphyrin IX in liver and hepatocyte cultures.
Topics: Animals; Carrier Proteins; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Heme-Binding Proteins; Hemeproteins; Liver; Male; Metalloporphyrins; Protein Synthesis Inhibitors; Protoporphyrins; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic | 1997 |
Inhibitory effect of selenium on enzymes involved in heme biosynthetic pathway in chick embryos.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Chick Embryo; Dactinomycin; Enzyme Inhibitors; Heme; Liver; Porphobilinogen Synthase; Porphyrins; Protein Synthesis Inhibitors; Selenium; Sulfhydryl Compounds; Time Factors | 1996 |
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures.
Topics: Animals; Arteries; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Blotting, Northern; Cells, Cultured; Chelating Agents; Cobalt; Dactinomycin; Deferoxamine; Fluorescent Dyes; Heme; Hepatocytes; Immunoblotting; Male; Nucleic Acid Synthesis Inhibitors; Oxygen; Rats; Rats, Wistar; Rhodamine 123; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Veins | 2000 |
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Blotting, Northern; Blotting, Western; Cattle; Cell Line; Cobalt; Dactinomycin; Deferoxamine; Dimerization; Fanconi Anemia Complementation Group Proteins; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoxia; Interferon-gamma; Leucine Zippers; Luciferases; Membrane Proteins; Models, Genetic; Oxidative Stress; Oxygen; Promoter Regions, Genetic; Rats; RNA, Messenger; Time Factors; Transcription Factors; Transfection; Tumor Cells, Cultured | 2003 |
THE ROLE OF COENZYMES, CORTISONE AND RNA IN THE CONTROL OF LIVER ENZYME LEVELS.
Topics: Adrenalectomy; Coenzymes; Cortisone; Dactinomycin; Heme; Hydro-Lyases; Liver; Metabolism; Peroxidases; Pharmacology; Puromycin; Rats; Research; RNA; Threonine; Transaminases; Tryptophan | 1963 |
HAEMPROTEINS IN HEART MICROSOMES. II. A POSSIBLE ROLE FOR HAEMPROTEOLIPID IN HAEMPROTEIN BIOSYNTHESIS.
Topics: Ascorbic Acid; Chloramphenicol; Dactinomycin; Heme; Hemeproteins; Iron; Iron Isotopes; Microsomes; Myocardium; NAD; Pharmacology; Phenylalanine; Porphyrins; Proteins; Research; Surface-Active Agents | 1965 |
An alternatively-spliced exon in the 5'-UTR of human ALAS1 mRNA inhibits translation and renders it resistant to haem-mediated decay.
Topics: 5-Aminolevulinate Synthetase; 5' Untranslated Regions; Alternative Splicing; Cell Line, Tumor; Dactinomycin; Exons; Heme; Humans; Protein Biosynthesis; RNA Stability; RNA, Messenger | 2005 |
Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Topics: 5-Aminolevulinate Synthetase; Cell Line, Tumor; Cycloheximide; Dactinomycin; Down-Regulation; Gene Expression Regulation, Enzymologic; Half-Life; Heme; Hepatocytes; Humans; Mitochondrial Proteins; Nucleic Acid Synthesis Inhibitors; Porphyria, Acute Intermittent; Protein Synthesis Inhibitors; Protoporphyrins; RNA, Messenger | 2008 |
A Central Role for Heme Oxygenase-1 in the Control of Intestinal Epithelial Chemokine Expression.
Topics: Caco-2 Cells; Cell Line, Tumor; Chemokines; Colitis; Dactinomycin; Gene Knockdown Techniques; Heme; Heme Oxygenase-1; Humans; Interleukin-1beta; Intestinal Mucosa; Leukocytes; Salmonella typhimurium; THP-1 Cells; Transcription, Genetic | 2018 |