heme has been researched along with cycloheximide in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 95 (85.59) | 18.7374 |
| 1990's | 11 (9.91) | 18.2507 |
| 2000's | 4 (3.60) | 29.6817 |
| 2010's | 1 (0.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, H | 1 |
| Ross, E; Schatz, G | 1 |
| Woods, JS | 2 |
| Barwick, JL; Guzelian, PS | 1 |
| Bissell, DM; Liem, HH; Muller-Eberhard, U | 1 |
| Maines, MD; Sinclair, P | 1 |
| Holbrook, DJ; Krasny, HC | 1 |
| de Matteis, F; Gibbs, AH; Järvisalo, J | 1 |
| Fuhr, JE; Townes, TM | 1 |
| De Matteis, F | 1 |
| Padmanaban, G; Rajamanickam, C; Rao, MR | 1 |
| Deitrich, RA; Erwin, G; Troxell, PA | 1 |
| Badawy, AA; Evans, M | 1 |
| Israels, LG; Schacter, BA; Yoda, B | 1 |
| Robinson, SH; Yannoni, CZ | 1 |
| Chen, JJ; Dhindsa, RS; Levin, D; London, IM; Ramaiah, KV | 1 |
| Apple, F; Balla, G; Balla, J; Eaton, JW; Jacob, HS; Nath, K; Rosenberg, M; Vercellotti, GM | 1 |
| den Blaauwen, J; Mattia, E; van Renswoude, J | 1 |
| Gross, M; Rubino, MS | 1 |
| Kaliman, PA; Manandkhar, SP; Nikitchenko, IV | 1 |
| Padmanaban, G; Rangarajan, PN | 1 |
| DeFalco, MG; Giffhorn-Katz, S; Grasso, JA; Katz, NR; Liem, HH; Muller-Eberhard, U | 1 |
| Bement, WJ; Hamilton, JW; Sinclair, JF; Sinclair, PR; Wetterhahn, KE | 1 |
| Bonkovsky, HL; Healey, JF; Lincoln, BC | 1 |
| Cox, TM; Gardner, LC | 1 |
| Kuroiwa, Y; Numazawa, S; Oguro, T; Yoshida, T | 1 |
| Belovetskaia, IV; Kaliman, PA | 1 |
| Engel, P; Marver, HS; Pimstone, NR; Schmid, R; Seitz, PT; Tenhunen, R | 2 |
| Liem, HH; Muller-Eberhard, U; Smibert, E | 1 |
| Neuwirt, J; Ponka, P; Prchal, J | 1 |
| Weiss, H; Ziganke, B | 1 |
| Kleinow, W; Lorenz, B; Weiss, H | 1 |
| Bottomley, SS; Moore, MA; Smithee, GA; Whitcomb, WH | 1 |
| Clegg, RA; Garland, PB | 1 |
| Machleidt, W; Otto, J; Sebald, W | 1 |
| Charalampous, FC | 1 |
| Kikuchi, G; Kim, HJ; Oashi, A; Tomita, Y; Watarai, K | 1 |
| Nebert, DW | 1 |
| Garland, PB; Ragan, CI | 1 |
| Martinez-Medellin, J; Schulman, HM; Sidloi, R | 1 |
| Rabinovitz, M | 1 |
| Kikuchi, G; Oashi, A | 1 |
| Hunter, AR; Jackson, RJ | 1 |
| Marks, GS; Tyrrell, DL | 1 |
| Borová, J; Neuwirt, J; Ponka, P | 5 |
| Gayathri, AK; Padmanaban, G; Rao, MR | 1 |
| Abbritti, G; De Matteis, F; Gibbs, AH | 1 |
| Dupont, CH | 1 |
| Freedman, ML; Karpatkin, S | 1 |
| Balkow, K; Fisher, JM; Mizuno, S; Rabinovitz, M | 1 |
| Balkow, K; Mizuno, S; Rabinovitz, M | 1 |
| Nichol, AW | 1 |
| Manning, J; Marver, HS; Strand, LJ | 1 |
| Strauss, PR | 1 |
| Hunt, T; London, IM; Vanderhoff, G | 1 |
| Hayashi, N; Kikuchi, G; Kurashima, Y | 2 |
| Malathi, K; Padmanaban, G; Rao, MR | 1 |
| Imai, Y; Siekevitz, P | 1 |
| Jayaraman, J; Malathi, K; Padmanaban, G; Sarma, PS | 1 |
| Marks, GS; Schneck, DW; Tyrrell, DL | 1 |
| Granick, S; Kappas, A | 1 |
| Bausserman, LL; Nebert, DW | 1 |
| Goldwasser, E; Hrinda, ME | 1 |
| Garner, RC; McLean, AE | 1 |
| Bond, EJ; De Matteis, F | 1 |
| Brezík, Z; Neuwirt, J; Ponka, P; Sperl, M | 1 |
| Hasegawa, E; Smith, C; Tephly, TR | 1 |
| Bock, KW; Siekevitz, P | 1 |
| Neuwirt, J; Ponka, P | 2 |
| Padmanaban, G; Sarma, PS; Subramanian, KN | 1 |
| Israels, LG; Levitt, M; Schacter, BA; Zipursky, A | 1 |
| Kappas, A; Song, CS | 1 |
| Hayashi, N; Kikuchi, G; Yoda, B | 1 |
| Borová, J; Neuwirt, J; Ponka, P; Prchal, JF | 1 |
| Schiefer, HG | 1 |
| Muthukrishnan, S; Padmanaban, G; Sarma, PS | 1 |
| Fuhr, JE; Grayzel, AI; London, IM | 1 |
| Kumar, CC; Padmanaban, G | 1 |
| Cánepa, ET; Grinstein, M; Llambías, EB | 1 |
| Gopalan, G; Jayaraman, J; Rajamanickam, C | 1 |
| Iacopetta, B; Morgan, E | 1 |
| Ades, IZ; Harpe, KG; Stevens, TM | 1 |
| Omura, T; Sadano, H | 1 |
| Ibrahim, NG; Levere, RD; Lutton, JD | 1 |
| Beattie, DS; Clejan, L; Gollub, EG; Liu, KP; Sprinson, DB | 1 |
| Atsmon, A; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N | 1 |
| Bissell, DM; Grandchamp, B; Licko, V; Schmid, R | 1 |
| Ord, JM; Wildenthal, K | 1 |
| Correia, MA; Farrell, GC | 1 |
| Hayashi, N; Kikuchi, G; Terasawa, M | 1 |
| Bhattacharyya-Pakrasi, M; Gang, H; Goessling, LS; Mascotti, DP; Thach, RE | 1 |
| Goldberg, MA; Schneider, TJ | 1 |
| Babu, SV; Ramaiah, KV | 1 |
| Gage, AT; Stanton, PK | 1 |
| Battle, A; Fukuda, H; Riley, P; Washbrook, R | 1 |
| Immenschuh, S; Iwahara, S; Katz, N; Muller-Eberhard, U; Nell, C | 1 |
| Aldieri, E; Bosia, A; Costamagna, C; Garbarino, G; Ghigo, D; Pescarmona, G; Todde, R | 1 |
| Dolan, KG; Garrick, LM; Garrick, MD; Kulju, D; Romano, MA; Scott, D | 1 |
| Arruda, MA; Barja-Fidalgo, C; de Freitas, MS; Graça-Souza, AV; Rossi, AG | 1 |
| Barannik, T; Inshina, N; Kaliman, PA; Sokol, O; Strel'chenko, E | 1 |
| Brecht, K; Heim, J; Simonen, M | 1 |
| Bonkovsky, HL; Donohue, SE; Lambrecht, RW; Shan, Y; Zheng, J | 1 |
| Carter, EL; Gupta, N; Ragsdale, SW | 1 |
2 review(s) available for heme and cycloheximide
| Article | Year |
|---|---|
Subunit composition and biogenesis of mitochondrial cytochrome b.
Topics: Amino Acids; Animals; Cattle; Chloramphenicol; Cycloheximide; Cytochromes; Grasshoppers; Heme; Macromolecular Substances; Mitochondria; Mitochondria, Muscle; Molecular Weight; Myocardium; Neurospora crassa; Protein Biosynthesis; Saccharomyces cerevisiae; Species Specificity; Spectrophotometry | 1976 |
The effect of drugs on 5-aminolaevulinate synthetase and other enzymes in the pathway of liver haem biosynthesis.
Topics: 5-Aminolevulinate Synthetase; Animals; Animals, Newborn; Cycloheximide; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Induction; Griseofulvin; Heme; Liver; Microsomes, Liver; Pharmacology; Phenylbutazone; Porphyrias; Porphyrins; Proadifen; Protein Biosynthesis | 1975 |
109 other study(ies) available for heme and cycloheximide
| Article | Year |
|---|---|
Cytochrome c1 of bakers' yeast. II. Synthesis on cytoplasmic robosomes and influence of oxygen and heme on accumulation of the apoprotein.
Topics: Acriflavine; Apoproteins; Cycloheximide; Cytochrome c Group; Cytochromes c1; Cytoplasm; Heme; Mitochondria; Molecular Weight; Oxygen Consumption; Precipitin Tests; Ribosomes; Saccharomyces cerevisiae | 1976 |
Heme regulation of cytochrome oxidase synthesis in fetal rat liver.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cobalt; Cycloheximide; Electron Transport Complex IV; Female; Fetus; Heme; In Vitro Techniques; Leucine; Mitochondria, Liver; Pregnancy; Rats; Time Factors | 1977 |
Inhibition by cycloheximide of degradation of cytochrome P-450 in primary cultures of adult rat liver parenchymal cells and in vivo.
Topics: Animals; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes, Liver; Proteins; Rats | 1979 |
Secretion of haem by hepatic parenchymal cells.
Topics: Albumins; Aminolevulinic Acid; Animals; Cells, Cultured; Cycloheximide; Extracellular Space; Heme; Hemopexin; In Vitro Techniques; Liver; Male; Perfusion; Rats; Secretory Rate | 1979 |
Cobalt regulation of heme synthesis and degradation in avian embryo liver cell culture.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cobalt; Cycloheximide; Dactinomycin; Enzyme Induction; Heme; Iron; Liver; Maleates; Mixed Function Oxygenases | 1977 |
Effects of cadmium on heme oxygenase and hemoproteins in smooth and rough endoplasmic reticulum of rat liver.
Topics: Animals; Cadmium; Cycloheximide; Dactinomycin; Endoplasmic Reticulum; Heme; Hemeproteins; Liver; Male; Mixed Function Oxygenases; Rats; RNA; Time Factors | 1978 |
Accelerated conversion of heme to bile pigments caused in the liver by carbon disulfide and other sulfur-containing chemicals.
Topics: Animals; Bile Pigments; Carbon Disulfide; Cycloheximide; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Sulfur | 1978 |
Protection by cycloheximide from hyperthermic inhibition of protein synthesis in human reticulocytes.
Topics: Cycloheximide; Female; Fetal Blood; Heme; Hemoglobins; Hot Temperature; Humans; Infant, Newborn; Isoniazid; Leucine; Pregnancy; Reticulocytes; Time Factors | 1977 |
On the sequence of reactions leading to cytochrome P-450 synthesis-effect of drugs.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Apoproteins; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Endoplasmic Reticulum; Glycine; Heme; Iron; Liver; Male; Microsomes, Liver; Phenobarbital; Rats | 1975 |
Characteristics of the induction of aldehyde dehydrogenase in rat liver.
Topics: Aldehyde Oxidoreductases; Allylisopropylacetamide; Animals; Cycloheximide; Cytosol; Enzyme Induction; Heme; Liver; Phenobarbital; Rats; Species Specificity; Time Factors | 1975 |
Regulation of rat liver tryptophan pyrrolase by its cofactor haem: Experiments with haematin and 5-aminolaevulinate and comparison with the substrate and hormonal mechanisms.
Topics: Aminolevulinic Acid; Apoenzymes; Cycloheximide; Dactinomycin; Hematinics; Heme; Hydrocortisone; Liver; Porphyrias; Porphyrinogens; Puromycin; Tryptophan; Tryptophan Oxygenase | 1975 |
Cyclic oscillations in rat hepatic heme oxygenase and delta-aminolevulinic acid synthetase following intravenous heme administration.
Topics: 5-Aminolevulinate Synthetase; Albumins; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Female; Heme; Liver; Microsomes, Liver; Oxygenases; Rats | 1976 |
Early labeled heme synthesis in normal rats and rats with iron deficiency anemia.
Topics: Anemia, Hypochromic; Animals; Cycloheximide; Erythrocytes; Glycine; Heme; Hemoglobins; Iron; Liver; Male; Microsomes, Liver; Organ Specificity; Rats | 1976 |
Recycling and phosphorylation of eukaryotic initiation factor 2 on 60S subunits of 80S initiation complexes and polysomes.
Topics: Animals; Cell-Free System; Cycloheximide; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Guanine Nucleotide Exchange Factors; Heme; In Vitro Techniques; Pactamycin; Phosphoproteins; Phosphorylation; Polyribosomes; Protein Kinases; Proteins; Puromycin; Rabbits; Reticulocytes; Ribosomes | 1992 |
Ferritin: a cytoprotective antioxidant strategem of endothelium.
Topics: Animals; Antioxidants; Aorta; Apoferritins; Arsenic; Arsenites; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Ferritins; Heme; Heme Oxygenase (Decyclizing); Horses; Humans; Hydrogen Peroxide; Kinetics; Lipid Peroxidation; Neutrophils; Recombinant Proteins; RNA, Messenger; Sodium Compounds; Swine | 1992 |
Role of protein synthesis in the accumulation of ferritin mRNA during exposure of cells to iron.
Topics: Cell Line; Cycloheximide; Dactinomycin; Ferritins; Heme; Humans; Iron; Kinetics; Pactamycin; Polyribosomes; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger; Transcription, Genetic | 1990 |
Regulation of eukaryotic initiation factor-2B activity by polyamines and amino acid starvation in rabbit reticulocyte lysate.
Topics: Amino Acids; Animals; Cell-Free System; Cycloheximide; Eukaryotic Initiation Factor-2; Heme; Kinetics; Phosphorylation; Rabbits; Reticulocytes; Spermidine; Spermine | 1989 |
[The role of heme in the regulation of tryptophan-2,3-dioxygenase activity and content of cytochrome P-450 in rat liver].
Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Drug Interactions; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Tryptophan Oxygenase | 1989 |
Regulation of cytochrome P-450b/e gene expression by a heme- and phenobarbitone-modulated transcription factor.
Topics: Animals; Base Sequence; Cell Nucleus; Cloning, Molecular; Cycloheximide; Cytochrome P-450 Enzyme System; Exons; Gene Expression Regulation; Genes; Heme; Liver; Molecular Sequence Data; Phenobarbital; Rats; Reference Values; Transcription Factors; Transcription, Genetic | 1989 |
Increase in surface expression of transferrin receptors on cultured hepatocytes of adult rats in response to iron deficiency.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Cycloheximide; Deferoxamine; Heme; Heptanoates; Kinetics; Liver; Mannans; Rats; Receptors, Transferrin; Reference Values | 1988 |
Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Dose-Response Relationship, Drug; Enzyme Induction; Heme; Liver; RNA, Messenger | 1988 |
Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
Topics: Animals; Cations, Divalent; Cells, Cultured; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Glutethimide; Heme; Heme Oxygenase (Decyclizing); Liver; Mephenytoin; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Porphyrins | 1988 |
Biosynthesis of heme in immature erythroid cells. The regulatory step for heme formation in the human erythron.
Topics: Adolescent; Adult; Aminolevulinic Acid; Anemia, Sickle Cell; Animals; Bone Marrow; Child; Cycloheximide; Feedback; Female; Globins; Glycine; Heme; Humans; Iron Radioisotopes; Kinetics; Male; Methionine; Middle Aged; Protein Biosynthesis; Rabbits; Reticulocytes; Transferrin | 1988 |
Effects of phorone (diisopropylidene acetone), a glutathione (GSH) depletor, on hepatic enzymes involved in drug and heme metabolism in rats: evidence that phorone is a potent inducer of heme oxygenase.
Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Glutathione; Heme; Heme Oxygenase (Decyclizing); Ketones; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Solvents | 1987 |
[Effect of cobalt chloride on the activity of key enzymes of heme metabolism in the rat liver].
Topics: 5-Aminolevulinate Synthetase; Animals; Cobalt; Cycloheximide; Dactinomycin; Enzyme Activation; Heme; Heme Oxygenase (Decyclizing); Kinetics; Liver; Rats; Rats, Inbred Strains; Tryptophan Oxygenase | 1986 |
Further studies of microsomal haem oxygenase: mechanism for stimulation of enzyme activity and cellular localization.
Topics: Albumins; Animals; Bile Pigments; Bilirubin; Chemical Phenomena; Chemistry; Cycloheximide; Dactinomycin; Enzyme Activation; Heme; Hemoglobins; Kidney; Liver; Macrophages; Microsomes; Mononuclear Phagocyte System; Oxygenases; Puromycin; Rats; Spleen; Zymosan | 1971 |
Studies on the induction of serum hemopexin by pentobarbital and polycyclic hydrocarbons.
Topics: Animals; Benzopyrenes; Beta-Globulins; Chloramphenicol; Cycloheximide; Drug Tolerance; Heme; Hemopexin; Immunodiffusion; Male; Methylcholanthrene; Pentobarbital; Polycyclic Compounds; Rabbits; Starvation; Time Factors | 1972 |
Heme synthesis in impaired globin synthesis.
Topics: Animals; Blood Proteins; Carbon Isotopes; Cycloheximide; Globins; Glycine; Heme; Iron Isotopes; Rabbits; Reticulocytes | 1968 |
Cytochrome b in Neurospora crassa mitochondria. Site of translation of the heme protein.
Topics: Chloramphenicol; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Cytochromes; Electrophoresis, Polyacrylamide Gel; Heme; Iron; Iron Radioisotopes; Leucine; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Oxidation-Reduction; Protein Biosynthesis; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Mitochondrial translation of cytochrome b in Neurospora crassa and Locusta migratoria.
Topics: Animals; Apoproteins; Cycloheximide; Cytochromes; DNA; Electrophoresis, Polyacrylamide Gel; Grasshoppers; Heme; Leucine; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Oxidation-Reduction; Protein Biosynthesis; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Effect of cyclic adenosine-3',5'-monophosphate on bone marrow delta-aminolevulinic acid synthetase and erythrocyte iron uptake.
Topics: Acyltransferases; Adenine Nucleotides; Amino Acids; Animals; Bone Marrow; Bone Marrow Cells; Culture Techniques; Cyclic AMP; Cycloheximide; Dactinomycin; Erythrocytes; Erythropoiesis; Erythropoietin; Heme; Iron; Iron Isotopes; Levulinic Acids; Mice; Mitochondria; Rabbits; Stimulation, Chemical; Succinates; Theophylline | 1971 |
Non-haem iron and the dissociation of piericidin A sensitivity from site 1 energy conservation in mitochondria from Torulopsis utilis.
Topics: Chloramphenicol; Cycloheximide; Cytochromes; Electron Transport; Energy Transfer; Erythromycin; Flavoproteins; Glycerol; Heme; Iron; Iron Isotopes; Malates; Mitochondria; Mitosporic Fungi; NAD; Oxygen Consumption; Proteins; Pyridines; Pyruvates; Rotenone; Sulfur; Tetracycline; Time Factors | 1971 |
Products of mitochondrial protein synthesis in Neurospora crassa. Determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis.
Topics: Amino Acids; Carbon Radioisotopes; Chloramphenicol; Cycloheximide; Dialysis; Drug Resistance, Microbial; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Heme; Leucine; Membranes; Mitochondria; Molecular Weight; Neurospora; Neurospora crassa; Peptides; Sodium Dodecyl Sulfate; Spectrophotometry; Tritium | 1973 |
Coproporphyrin 3, inhibitor of the synthesis of cytochrome oxidase in anaerobic yeast protoplasts.
Topics: Acridines; Aerobiosis; Anaerobiosis; Apoproteins; Chloramphenicol; Cycloheximide; Cytoplasm; Dose-Response Relationship, Drug; Electron Transport Complex IV; Heme; Mitochondria; Oxygen; Peptide Biosynthesis; Porphyrins; Protein Biosynthesis; Protoplasts; Saccharomyces; Transcription, Genetic | 1974 |
Comparative study on induction of hepatic delta-aminolevulinate synthetase by different drugs.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Animals; Bucladesine; Cells, Cultured; Chick Embryo; Cycloheximide; Cytosol; Dicarboxylic Acids; Enzyme Induction; Heme; Liver; Mitochondria, Liver; Phenobarbital; Pyridines; Rats; Species Specificity; Time Factors | 1973 |
Microsomal cytochromes b5 and P450 during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture.
Topics: Animals; Benz(a)Anthracenes; Carbon Monoxide; Cricetinae; Culture Techniques; Cycloheximide; Cytochromes; Depression, Chemical; Enzyme Activation; Enzyme Induction; Female; Fetus; Heme; Hydrocarbons; Liver; Maternal-Fetal Exchange; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pigments, Biological; Pregnancy; Protein Biosynthesis; Rats; Spectrophotometry; Stimulation, Chemical; Time Factors | 1970 |
Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism.
Topics: Adaptation, Physiological; Animals; Bilirubin; Bone Marrow; Cycloheximide; Dactinomycin; Disease Models, Animal; Enzyme Induction; Female; Heme; Hemoglobins; Hemoglobinuria; Homeostasis; Injections, Intravenous; Iron Isotopes; Kidney Tubules; Liver; NADP; Oxygenases; Protein Biosynthesis; Puromycin; Rats; RNA; Spleen | 1971 |
Spectroscopic studies of flavoproteins and non-haem iron proteins of submitochondrial particles of Torulopsis utilis modified by iron- and sulphate-limited growth in continuous culture.
Topics: Cycloheximide; Cytochromes; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavoproteins; Glycerolphosphate Dehydrogenase; Heme; Iron; Mitochondria; Mitosporic Fungi; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Proteins; Spectrum Analysis; Succinate Dehydrogenase; Sulfates; Sulfides; Ubiquinone | 1971 |
The reticulocyte-mediated release of iron and bicarbonate from transferrin: effect of metabolic inhibitors.
Topics: Animals; Antimetabolites; Arsenic; Azides; Bicarbonates; Binding Sites; Carbon Radioisotopes; Cobalt; Cyanides; Cycloheximide; Dinitrophenols; Ethylmaleimide; Fluorides; Heme; Iodoacetates; Iron; Iron Radioisotopes; Isoniazid; Oligomycins; Protein Binding; Reticulocytes; Rotenone; Time Factors; Transferrin | 1974 |
Translational repression in the control of globin chain initiation by hemin.
Topics: Animals; Carbon Radioisotopes; Centrifugation, Density Gradient; Codon; Cycloheximide; Globins; Heme; Hemin; Kinetics; Leucine; Methionine; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Reticulocytes; Ribose; Ribosomes; RNA, Messenger; RNA, Transfer; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Temperature; Time Factors | 1974 |
Mechanism of allylisopropylacetamide-induced increase of -aminolevulinate synthetase in liver mitochondria. VI. Multiple molecular forms of -aminolevulinate synthetase in the cytosol and mitochondria of induced cock liver.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allyl Compounds; Animals; Centrifugation, Density Gradient; Chickens; Chromatography, Gel; Coenzyme A Ligases; Cycloheximide; Cytosol; Escherichia coli; Heme; Kinetics; Liver; Macromolecular Substances; Male; Mitochondria, Liver; Molecular Weight; Sodium Chloride; Succinates | 1972 |
Control of haemoglobin synthesis: coordination of alpha and beta chain synthesis.
Topics: Animals; Carbon Radioisotopes; Chromatography, Gel; Cycloheximide; Globins; Heme; Hemoglobins; Humans; Iron; Lysine; Peptide Chain Initiation, Translational; Peptide Fragments; Puromycin; Rabbits; Reticulocytes; Thalassemia; Tritium | 1972 |
Drug-induced porphyrin biosynthesis. V. Effect of protohemin on the transcriptional and post-transcriptional phases of -aminolevulinic acid synthetase induction.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Dicarboxylic Acids; Enzyme Induction; Heme; Liver; Porphyrins; Pyridines; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium; Uridine | 1972 |
The use of exogenous -aminolaevulinic acid for the studies of the regulation of haem synthesis in rabbit reticulocytes.
Topics: 5-Aminolevulinate Synthetase; Age Factors; Animals; Carbon Isotopes; Cycloheximide; Globins; Glycine; Heme; In Vitro Techniques; Iron; Iron Isotopes; Isoniazid; Levulinic Acids; Models, Chemical; Penicillamine; Protein Binding; Rabbits; Reticulocytes; Transferrin | 1973 |
Studies on the induction of -aminolevulinic acid synthetase iun mouse liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Cycloheximide; Cytosol; Dactinomycin; Dicarboxylic Acids; Enzyme Induction; Female; Half-Life; Heme; Kinetics; Liver; Mice; Mitochondria, Liver; Molecular Weight; Pyridines; Spectrophotometry; Starvation; Subcellular Fractions; Time Factors | 1973 |
Accumulation of heme in mitochondria from rabbit reticulocytes with inhibited globin synthesis.
Topics: Animals; Cattle; Cycloheximide; Globins; Heme; Iron; Iron Isotopes; Mitochondria; Rabbits; Reticulocytes; Serum Albumin, Bovine; Transferrin | 1973 |
Decreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and mice.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Dicarboxylic Acids; Heme; Iron; Iron Radioisotopes; Levulinic Acids; Liver Diseases; Lyases; Male; Mice; Mitochondria, Liver; Porphyrias; Porphyrins; Proadifen; Pyridines; Rats; Species Specificity | 1973 |
The site of hemoglobin synthesis in the avian erythrocyte.
Topics: Animals; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Columbidae; Cycloheximide; Erythrocytes; Heme; Hemoglobins; Isotope Labeling; Kinetics; Leucine; Membranes; Microscopy, Electron; Puromycin; Ribosomes; Saponins; Surface-Active Agents; Time Factors | 1973 |
Requirement of iron for platelet protein synthesis.
Topics: Amino Acids; Animals; Blood Platelets; Blood Proteins; Carbon Radioisotopes; Chelating Agents; Cycloheximide; Heme; Iron; Phenylhydrazines; Puromycin; Pyridines; Rabbits; Transferrin | 1973 |
Hemin control of globin synthesis: effect of a translational repressor on Met-tRNAf binding to the small ribosomal subunit and its relation to the activity and alailability of an initiation factor.
Topics: Animals; Cell Fractionation; Centrifugation, Zonal; Chromatography, Ion Exchange; Cycloheximide; Formates; Globins; Heme; Methionine; Peptide Initiation Factors; Potassium Chloride; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer; Subcellular Fractions; Sulfur Radioisotopes; Suppression, Genetic | 1973 |
Inhibition of an initiation codon function by hemin deficiency and the hemin-controlled translational repressor in the reticulocyte cell-free system.
Topics: Animals; Anti-Bacterial Agents; Cell-Free System; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Genes, Regulator; Heme; Methionine; Oligonucleotides; Oligopeptides; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Peptides; Polyamines; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; RNA, Transfer; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes | 1973 |
The role of heme in the release of iron from transferrin in reticulocytes.
Topics: Animals; Cycloheximide; Heme; Iodine Radioisotopes; Iron; Iron Radioisotopes; Isoniazid; Mitochondria; Protein Binding; Pyridines; Rabbits; Reticulocytes; Transferrin | 1974 |
Heme and the production of delta-aminolevulinic acid in rabbit reticulocytes.
Topics: 5-Aminolevulinate Synthetase; Animals; Carbon Radioisotopes; Cattle; Cycloheximide; Globins; Glycine; Heme; Iron; Iron Radioisotopes; Isoniazid; Levulinic Acids; Mitochondria; Pyridines; Rabbits; Reticulocytes; Serum Albumin, Bovine; Time Factors | 1974 |
Studies on the role of heme in the regulation of delta-aminolevulinic acid synthetase during fetal hepatic development.
Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Endoplasmic Reticulum; Fetus; Heme; Liver; Microsomes, Liver; Protein Biosynthesis; Rats; Rats, Inbred Strains; Time Factors; Triazoles | 1974 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
The induction of -aminolevulinic acid synthetase in cultured liver cells. The effects of end product and inhibitors of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acetates; Acyltransferases; Allyl Compounds; Animals; Carbon Isotopes; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Repression; Heme; Humans; Iron; Iron Isotopes; Kinetics; Lead; Levulinic Acids; Liver; Porphyrias; Succinates; Tritium | 1972 |
Acriflavin resistance in the hemoflagellate, Leishmania tarentolae.
Topics: Acridines; Amines; Arginine; Autoradiography; Cell Nucleus; Chloramphenicol; Chromatography, Paper; Cycloheximide; Ethidium; Heme; Histocytochemistry; Leishmania; Methods; Microbial Sensitivity Tests; Microscopy, Electron; Microscopy, Fluorescence; Phenanthridines; Time Factors; Tritium | 1972 |
Evidence for the presence of free and protein-bound nonhemoglobin heme in rabbit reticulocytes.
Topics: Animals; Blood Proteins; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Glycine; Heme; Hemoglobins; In Vitro Techniques; Iron; Iron Isotopes; Isoniazid; Protein Binding; Rabbits; Reticulocytes | 1972 |
Control of globin synthesis: the role of heme.
Topics: Animals; Cattle; Cycloheximide; Cytoplasm; Fluorides; Globins; Heme; In Vitro Techniques; Peptide Chain Initiation, Translational; Polynucleotides; Rabbits; Reticulocytes; Ribosomes; Serum Albumin; Serum Albumin, Bovine; Stimulation, Chemical; Temperature | 1972 |
Mechanism of allylisopropylacetamide-induced increase of -aminolevulinate synthetase in liver mitochondria. V. Mechanism of regulation by hemin of the level of -aminolevulinate synthetase in rat liver mitochondria.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acyltransferases; Allyl Compounds; Animals; Bilirubin; Cycloheximide; Dactinomycin; Enzyme Induction; Heme; Hydrocortisone; Kinetics; Liver; Male; Mitochondria, Liver; Rats; Subcellular Fractions | 1972 |
The relationship between delta-aminolaevulinate synthetase induction and the concentration of cytochrome P-450 and catalase in rat liver.
Topics: 5-Aminolevulinate Synthetase; Amides; Animals; Bilirubin; Catalase; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucose; Half-Life; Heme; Liver; Microsomes, Liver; Phenobarbital; Porphyrins; Proadifen; Rats | 1972 |
A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats.
Topics: 1-Propanol; Amines; Animals; Chemical Phenomena; Chemistry; Chlorides; Cycloheximide; Cytochromes; Fasting; Fatty Alcohols; Heme; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Mercury; Methylcholanthrene; Microsomes, Liver; Nitriles; Oxidation-Reduction; Phenobarbital; Potassium; Protein Biosynthesis; Rats; Spectrophotometry; Sulfites; Thiocyanates; Triazoles | 1971 |
Haem synthesis during mitochondrogenesis in yeast.
Topics: Chloramphenicol; Cycloheximide; Glucose; Heme; Hydro-Lyases; Ligases; Mitochondria; Oxygen Consumption; Proteins; Saccharomyces | 1971 |
Drug-induced porphyrin biosynthesis. 3. Inhibition of drug-induced porphyria by protohemin.
Topics: Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Depression, Chemical; Glutarates; Glutethimide; Griseofulvin; Heme; Liver; Phthalic Acids; Porphyrias; Porphyrins; Pyridines | 1971 |
Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites.
Topics: Animals; Chick Embryo; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Repression; Etiocholanolone; Glucuronates; Heme; Liver; Mitomycins; Porphyrins; Puromycin; Steroids; Uracil Nucleotides | 1967 |
Aryl hydrocarbon hydroxylase induction in cell culture as a function of gene expression.
Topics: Aging; Animals; Animals, Newborn; Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Cell Line; Cricetinae; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Female; Fetus; Fluorometry; Gestational Age; Half-Life; Heme; Kinetics; Liver; Mice; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Molecular Biology; Pregnancy; Spectrophotometry; Tritium | 1971 |
On the mechanism of erythropoietin-induced differentiation. VI. Induced accumulation of iron by marrow cells.
Topics: Animals; Blood Proteins; Bone Marrow; Bone Marrow Cells; Cattle; Cell Differentiation; Chromatography, Gel; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Depression, Chemical; Erythropoiesis; Erythropoietin; Femur; Ferritins; Heme; Iron; Iron Isotopes; Male; Metabolism; Puromycin; Rats; RNA; Sheep; Stimulation, Chemical; Tibia; Time Factors; Transferrin | 1969 |
Separation of haem incorporation from protein synthesis in liver microsomes.
Topics: Animals; Carbon Isotopes; Cycloheximide; Cytochromes; Heme; Leucine; Levulinic Acids; Microsomes, Liver; Protein Biosynthesis; Rats | 1969 |
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes.
Topics: Adjuvants, Anesthesia; Aniline Compounds; Animals; Anisoles; Blood Proteins; Body Weight; Carbon Disulfide; Carbon Isotopes; Cycloheximide; Cytochromes; DNA; Fasting; Heme; Injections, Intraperitoneal; Leucine; Lipids; Liver; Liver Glycogen; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organ Size; Phenobarbital; Proadifen; Protein Biosynthesis; Proteins; Rats; RNA; Spectrophotometry; Sucrose; Time Factors | 1969 |
The ability of exogenous heme to restore globin synthesis in reticulocytes with impaired heme formation.
Topics: Amino Acids; Animals; Blood Proteins; Bloodletting; Carbon Isotopes; Cycloheximide; Depression, Chemical; Globins; Glycine; Heme; Hemoglobins; Hydrazines; Isonicotinic Acids; Methionine; Peptide Biosynthesis; Rabbits; Radioisotopes; Reticulocytes; Selenium; Stimulation, Chemical; Time Factors | 1970 |
Mechanism of inhibition by hemin of increase of delta-aminolevulinate synthetase in liver mitochondria.
Topics: Acetates; Animals; Cycloheximide; Dactinomycin; Heme; In Vitro Techniques; Levulinic Acids; Ligases; Male; Mitochondria, Liver; Rats | 1970 |
Induction of hepatic mitochondrial ferrochelatase by phenobarbital.
Topics: Acyltransferases; Animals; Cobalt; Cycloheximide; Enzyme Induction; Heme; Kinetics; Levulinic Acids; Liver; Lyases; Male; Metabolism; Mitochondria, Liver; Nickel; Oxygen; Phenobarbital; Porphyrins; Rats; Succinates | 1970 |
Turnover of heme and protein moieties of rat liver microsomal cytochrome b5.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cycloheximide; Cytochromes; Depression, Chemical; Guanidines; Half-Life; Heme; Kinetics; Leucine; Levulinic Acids; Male; Microsomes, Liver; Protein Biosynthesis; Proteins; Rats; Tritium | 1970 |
Regulation of iron entry into reticulocytes. II. Relationship between hemoglobin synthesis and entry of iron into reticulocytes.
Topics: Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chloramphenicol; Cycloheximide; Emetine; Fluorides; Globins; Glycine; Heme; Hemoglobins; In Vitro Techniques; Iron; Iron Isotopes; Isoniazid; Penicillamine; Puromycin; Pyridoxal Phosphate; Rabbits; Reticulocytes; Tryptamines | 1971 |
The regulation of nitrate reductase and catalase by amino acids in Neurospora crassa.
Topics: Amino Acids; Carbon Isotopes; Catalase; Cycloheximide; Depression, Chemical; Enzyme Induction; Enzyme Repression; Heme; Hydrogen Peroxide; Neurospora; Nitrates; Oxidoreductases | 1968 |
The nonerythropoietic component of early bilirubin.
Topics: Amides; Amino Acids; Animals; Bile Ducts; Biliary Fistula; Bilirubin; Carbon Isotopes; Catalase; Cycloheximide; Cytochromes; Erythropoiesis; Glycine; Heme; Infusions, Parenteral; Kidney; Lead Poisoning; Levulinic Acids; Male; Nephrectomy; Phenobarbital; Porphyrins; Protein Biosynthesis; Rats; Triazoles | 1968 |
Enzyme induction in the liver.
Topics: Cycloheximide; Dactinomycin; Enzyme Induction; Glucuronates; Heme; Humans; Liver; Microsomes; Mitomycins; Nucleic Acids; Porphyrins; Protein Biosynthesis; Puromycin; Ribosomes | 1968 |
Regulation of iron entry into reticulocytes. I. Feedback inhibitory effect of heme on iron entry into reticulocytes and on heme synthesis.
Topics: Animals; Chromatography; Cycloheximide; Globins; Heme; Hemoglobinometry; Iron; Iron Isotopes; Isonicotinic Acids; Rabbits; Rats; Reticulocytes; Spectrophotometry | 1969 |
Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. IV. Accumulation of the enzyme in the soluble fraction of rat liver.
Topics: Acyltransferases; Amides; Amino Acids; Animals; Bilirubin; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Stability; Enzyme Induction; Heme; Kinetics; Levulinic Acids; Liver; Male; Microsomes; Mitochondria, Liver; Mitomycins; Rats; Solubility; Stimulation, Chemical; Temperature | 1969 |
Problems of reduced heme synthesis in reticulocytes with impaired globin synthesis.
Topics: Animals; Blood Proteins; Carbon Isotopes; Citrates; Cycloheximide; Globins; Glycine; Heme; Iron Isotopes; Levulinic Acids; Ligases; Rabbits; Reticulocytes | 1969 |
Subcellular localization of the biosynthesis of the porphyrins and the haem components of cytochromes a, a3, and b in rat liver mitochondria.
Topics: Amino Acids; Animals; Chromatography, Thin Layer; Cycloheximide; Cytochromes; Depression, Chemical; Heme; In Vitro Techniques; Kinetics; Levulinic Acids; Liver; Microsomes; Mitochondria, Liver; Porphyrins; Rats; Tritium | 1969 |
The role of iron in heme synthesis in Neurospora crassa.
Topics: Amino Acids; Carbon Isotopes; Catalase; Cycloheximide; Enzyme Induction; Glycine; Heme; Iron; Neurospora; Plant Proteins | 1967 |
Effects of inhibitors of protein synthesis on the synthesis of heme in rabbit reticulocytes.
Topics: Alanine; Animals; Blood Proteins; Carbon Isotopes; Cycloheximide; Globins; Glycine; Heme; Puromycin; Rabbits; Reticulocytes; Spectrophotometry | 1967 |
Role of heme in the synthesis of cytochrome c oxidase in Neurospora crassa.
Topics: Chloramphenicol; Cycloheximide; Electron Transport Complex IV; Heme; Iron; Kinetics; Mitochondria; Neurospora; Neurospora crassa; Porphobilinogen Synthase; Protein Biosynthesis | 1980 |
Effect of glucose on the induction of delta-aminolevulinic acid synthase and ferrochelatase in isolated rat hepatocytes by allylisopropylacetamide.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Bucladesine; Carbohydrates; Cycloheximide; Enzyme Induction; Ferrochelatase; Gene Expression Regulation; Glucose; Heme; Liver; Lyases; Male; Rats | 1984 |
Effect of exogenous addition of hemin on the biogenesis of mitochondrial membranes during glucose repression in Saccharomyces cerevisiae.
Topics: Cycloheximide; Glucose; Heme; Hemin; Mitochondria; Oligomycins; Saccharomyces cerevisiae; Succinate Dehydrogenase; Time Factors | 1984 |
Heme inhibits transferrin endocytosis in immature erythroid cells.
Topics: Animals; Cycloheximide; Endocytosis; Erythrocyte Aging; Erythrocytes; Heme; Hemin; Heptanoates; Hydrogen-Ion Concentration; Iron; Isoniazid; Liver; Rabbits; Rats; Reticulocytes; Transferrin | 1984 |
Biogenesis of mitochondrial proteins. Regulation of production of delta-aminolaevulinate synthase by haemin in embryonic-chick liver.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Heme; Hemin; Immunoassay; In Vitro Techniques; Liver | 1983 |
Reversible transfer of heme between different molecular species of microsome-bound cytochrome P-450 in rat liver.
Topics: Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Heme; Isoenzymes; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats | 1983 |
The role of haem biosynthetic and degradative enzymes in erythroid colony development: the effect of haemin.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cycloheximide; Enzyme Activation; Erythropoiesis; Heme; Heme Oxygenase (Decyclizing); Hemin; Mice; Mice, Inbred BALB C; Porphobilinogen Synthase; Time Factors | 1982 |
Synthesis of the apoprotein of cytochrome b in heme-deficient yeast cells.
Topics: 5-Aminolevulinate Synthetase; Apoproteins; Cycloheximide; Cytochromes; Heme; Methionine; Mitochondria; Mutation; Peptide Fragments; Saccharomyces cerevisiae; Submitochondrial Particles | 1980 |
The influence of propranolol on the concentration of heme and on the activity of delta aminolevulinate synthase in monolayers of chick embryo liver cells.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Heme; Liver; Propranolol | 1982 |
Formation and disposition of newly synthesized heme in adult rat hepatocytes in primary culture.
Topics: Aminolevulinic Acid; Animals; Bile Pigments; Cells, Cultured; Cycloheximide; Heme; Kinetics; Liver; Male; Models, Biological; Rats; Rats, Inbred Strains | 1981 |
Increased release of delta-aminolevulinic acid from protein during inhibition of protein synthesis in heart: evidence for the extensive reutilization of heme in cardiac protein metabolism.
Topics: Aminolevulinic Acid; Animals; Cycloheximide; Heart; Heme; Levulinic Acids; Mice; Myocardium; Organ Culture Techniques; Phenylalanine; Proteins; Puromycin | 1980 |
Structural and functional reconstitution of hepatic cytochrome P-450 in vivo. Reversal of allylisopropylacetamide-mediated destruction of the hemoprotein by exogenous heme.
Topics: Acetamides; Allylisopropylacetamide; Animals; Cycloheximide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethylmorphine-N-Demethylase; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats | 1980 |
Immunochemical studies of the turnover of delta-aminolevulinate synthase in rat liver mitochondria and the effect of hemin on it.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cycloheximide; Cytosol; Heme; Immune Sera; Immunoassay; Kinetics; Liver; Mitochondria, Liver; Rats | 1980 |
Irreversible steps in the ferritin synthesis induction pathway.
Topics: Animals; Cell Line; Cycloheximide; Deferoxamine; Ferritins; Heme; In Vitro Techniques; Iron; Iron-Regulatory Proteins; Rabbits; RNA-Binding Proteins; Time Factors | 1994 |
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
Topics: Animals; Cobalt; Cycloheximide; Endothelial Growth Factors; Erythropoietin; Gene Expression Regulation; Genes, fos; Genes, jun; Heme; Humans; Hypoxia; In Vitro Techniques; Lymphokines; Oxygen; Rats; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1994 |
Type 1 phosphatase inhibitors reduce the restoration of guanine nucleotide exchange activity of eukaryotic initiation factor 2B inhibited reticulocyte lysates rescued by hemin.
Topics: Animals; Cell-Free System; Cycloheximide; eIF-2 Kinase; Enzyme Inhibitors; Ethers, Cyclic; Eukaryotic Initiation Factor-2; GTP-Binding Proteins; Guanosine Diphosphate; Heme; Kinetics; Okadaic Acid; Pactamycin; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Rabbits; Reticulocytes | 1996 |
Hypoxia triggers neuroprotective alterations in hippocampal gene expression via a heme-containing sensor.
Topics: Adaptation, Physiological; Animals; Biosensing Techniques; Cycloheximide; Dactinomycin; Excitatory Amino Acid Agonists; Gene Expression Regulation; Heme; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Stimulation of tetrapyrrole synthesis in mammalian epithelial cells in culture by exposure to aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Cattle; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Epithelium; gamma-Aminobutyric Acid; Glutamic Acid; Heme; Kinetics; Leucine; Mammals; Pyrroles; Radioisotope Dilution Technique; Tetrapyrroles | 1997 |
Gene regulation of HBP 23 by metalloporphyrins and protoporphyrin IX in liver and hepatocyte cultures.
Topics: Animals; Carrier Proteins; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Heme-Binding Proteins; Hemeproteins; Liver; Male; Metalloporphyrins; Protein Synthesis Inhibitors; Protoporphyrins; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic | 1997 |
Chloroquine stimulates nitric oxide synthesis in murine, porcine, and human endothelial cells.
Topics: Aconitate Hydratase; Animals; Calcium; Canavanine; Cell Division; Cell Line, Transformed; Chloroquine; Cycloheximide; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Guanidines; Heme; Humans; Hydrogen-Ion Concentration; Iron; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine Decarboxylase; Protein Synthesis Inhibitors; Stimulation, Chemical; Swine | 1998 |
Evidence for and consequences of chronic heme deficiency in Belgrade rat reticulocytes.
Topics: Anemia, Hypochromic; Animals; Cell-Free System; Cycloheximide; Disease Models, Animal; Heme; Heptanoates; Iron; Rats; Reticulocytes | 1999 |
Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB.
Topics: Active Transport, Cell Nucleus; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cycloheximide; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Hemolysis; Humans; I-kappa B Proteins; Interleukin-8; MAP Kinase Signaling System; Metalloporphyrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophils; NF-kappa B; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Protoporphyrins; Reactive Oxygen Species; Respiratory Burst; Transcription Factor RelA | 2004 |
Intracellular redistribution of heme in rat liver under oxidative stress: the role of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Animals; Cycloheximide; Enzyme Induction; Glutathione; Glycerol; Heme; Heme Oxygenase (Decyclizing); Hemolysis; Hydrogen Peroxide; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Oxidative Stress; Phenylhydrazines; Rats; Rats, Wistar; Rhabdomyolysis; Tryptophan Oxygenase; Unithiol | 2005 |
Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; B-Lymphocytes; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspases; Cell Line; Cisplatin; Cycloheximide; Cytochromes c; Doxorubicin; Globins; Green Fluorescent Proteins; HeLa Cells; Hematopoietic Stem Cells; Heme; Humans; Interleukin-3; K562 Cells; Mice; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Staurosporine; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Topics: 5-Aminolevulinate Synthetase; Cell Line, Tumor; Cycloheximide; Dactinomycin; Down-Regulation; Gene Expression Regulation, Enzymologic; Half-Life; Heme; Hepatocytes; Humans; Mitochondrial Proteins; Nucleic Acid Synthesis Inhibitors; Porphyria, Acute Intermittent; Protein Synthesis Inhibitors; Protoporphyrins; RNA, Messenger | 2008 |
High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbβ Leads to Its Degradation and Indirectly Regulates Its Interaction with Nuclear Receptor Corepressor.
Topics: Amino Acid Motifs; Apoproteins; Circadian Rhythm; Cycloheximide; Gene Expression Regulation; HEK293 Cells; Heme; Humans; Inflammation; Ions; Ligands; Mass Spectrometry; Metals; Myoglobin; Nuclear Receptor Co-Repressor 1; Promoter Regions, Genetic; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Transfection; Ubiquitin | 2016 |