Page last updated: 2024-08-23

heme and coumarin

heme has been researched along with coumarin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Anderson, KE; Goeger, DE1
Arvela, P; Mustajoki, P; Mustajoki, S; Pelkonen, O; Rautio, A1
Ahn, T; Jung, HC; Kim, D; Kim, DH; Pan, JG; Park, SH; Yun, CH1
Chen, S; Hong, J; Hong, Y; Li, Z; Liu, T; Zeng, S; Zheng, M1
Bagai, I; Becker, DF; Ragsdale, SW; Spencer, AL; Zuiderweg, ER1
Aktar, S; Caruso, F; Davis, M; Gahn, C; Hefter Feuss, E; Roman-Holba, S; Rossi, M; Wen, K1

Other Studies

6 other study(ies) available for heme and coumarin

ArticleYear
Coumarin-induced changes in delta-aminolaevulinic acid synthase and cytochrome P-450 in chick embryo liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Chick Embryo; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Liver; Microsomes; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Porphyrins

1991
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:1

    Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Humans; Isoenzymes; Lidocaine; Male; Middle Aged; Porphyrias, Hepatic; Reference Values

1994
Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5

    Topics: Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Carbon; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Stability; Escherichia coli; Heme; Humans; Indigo Carmine; Indoles; Kinetics; Molecular Dynamics Simulation; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxazines; Oxidation-Reduction; Phenacetin; Protein Engineering; Recombinant Proteins; Transformation, Genetic; Umbelliferones

2010
An investigation of the catalytic activity of CYP2A13*4 with coumarin and polymorphisms of CYP2A13 in a Chinese Han population.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Adult; Animals; Aryl Hydrocarbon Hydroxylases; Asian People; Binding Sites; Blotting, Western; Catalysis; Cell Line; Computer Simulation; Coumarins; DNA; Gene Frequency; Heme; Humans; Hydroxylation; Insecta; Models, Molecular; Mutagenesis, Site-Directed; Mutation, Missense; Polymerase Chain Reaction; Polymorphism, Single Nucleotide

2012
Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase.
    The Journal of biological chemistry, 2014, Oct-24, Volume: 289, Issue:43

    Topics: Apoproteins; Chromatography, Gel; Coumarins; Cross-Linking Reagents; Crystallography, X-Ray; Deuterium; Fluorescence; Heme; Heme Oxygenase (Decyclizing); Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Weight; Mutagenesis; Mutant Proteins; NADPH-Ferrihemoprotein Reductase; Oxidoreductases Acting on CH-CH Group Donors; Protein Binding; Surface Plasmon Resonance; Ultracentrifugation

2014
The Grapefruit Effect: Interaction between Cytochrome P450 and Coumarin Food Components, Bergamottin, Fraxidin and Osthole. X-ray Crystal Structure and DFT Studies.
    Molecules (Basel, Switzerland), 2020, Jul-10, Volume: 25, Issue:14

    Topics: Catalytic Domain; Citrus paradisi; Coumarins; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Furocoumarins; Heme; Humans; Hydrogen Bonding

2020