heme has been researched along with citrulline in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (60.00) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klatt, P; Mayer, B; Schmidt, K | 1 |
| Frey, C; Griffith, OW; Masters, BS; McMillan, K; Salerno, JC; Williams, RF | 1 |
| Griffith, OW; Narayanan, K | 1 |
| Fukuto, JM; Griscavage, JM; Ignarro, LJ; Komori, Y | 1 |
| Frey, C; Griffith, OW; Gross, SS; Masters, BS; McMillan, K; Narayanan, K; Spack, L | 1 |
| Marletta, MA; Olken, NM; Osawa, Y | 1 |
| Abu-Soud, HM; Clark, P; Feldman, PL; Stuehr, DJ | 1 |
| Boucher, JL; Delaforge, M; Mansuy, D; Renaud, JP; Vadon, S | 1 |
| Bächinger, HP; Glatter, O; Klatt, P; Lehner, D; List, BM; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Klatt, P; List, BM; Mayer, B; Schmidt, K; Werner, ER | 1 |
| Masters, BS; McMillan, K; Salerno, JC | 1 |
| Rousseau, DL; Stuehr, DJ; Wang, J | 1 |
| Evans, CH; Miller, LA; Möllers, MO; Stefanovic-Racic, M | 1 |
| Gorren, AC; Mayer, B; Schmidt, K; Schrammel, A | 1 |
| Hurshman, AR; Marletta, MA; Rusche, KM | 1 |
| Atkinson, RN; Ichimori, K; King, SB; Stuehr, DJ | 1 |
| Hayashi, Y; Hori, H; Iwasaki, T; Kurahashi, Y; Matsumura, T; Nishino, T | 1 |
| Ichikawa, Y; Kawazoe, T; Kosaka, H; Mizoguchi, K; Ohnishi, T; Yoneyama, H | 1 |
| Boggs, S; Huang, L; Stuehr, DJ | 1 |
| Gorren, AC; Koesling, D; Mayer, B; Riethmüller, C; Schmidt, K; Schrammel, A; Werner, ER | 1 |
| Adak, S; Stuehr, DJ; Wang, Q | 1 |
| Adak, S; Curran, CM; Santolini, J; Stuehr, DJ | 1 |
| Adak, S; Aulak, KS; Bilwes, AM; Crane, BR; Getzoff, ED; Hosfield, D; McDonald, JF; Panda, K; Stuehr, DJ; Tainer, JA | 1 |
| Porasuphatana, S; Pou, S; Rosen, GM; Tsai, P | 1 |
| Marks, N; Wolff, DJ | 1 |
| Cho, KB; Gauld, JW; Robinet, JJ | 1 |
| Chang, MM; Marletta, MA; Martin, NI; Woodward, JJ | 1 |
| Crane, BR; Davydov, R; Hoffman, BM; Lees, NS; Sudhamsu, J | 1 |
| Balland, V; Boucher, JL; Giroud, C; Mattioli, TA; Moreau, M; Santolini, J; Stuehr, DJ; Xu-Li, Y | 1 |
| Boucher, JL; Mansuy, D; Salard-Arnaud, I; Stuehr, D | 1 |
1 review(s) available for heme and citrulline
| Article | Year |
|---|---|
Catalysis by nitric oxide synthase.
Topics: Antioxidants; Arginine; Biopterins; Catalysis; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Hydrogen Peroxide; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase | 1998 |
29 other study(ies) available for heme and citrulline
| Article | Year |
|---|---|
Brain nitric oxide synthase is a haemoprotein.
Topics: Amino Acid Oxidoreductases; Animals; Brain; Carbon Monoxide; Citrulline; Heme; Miconazole; Nitric Oxide; Nitric Oxide Synthase; Potassium Cyanide; Spectrophotometry; Swine | 1992 |
Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Heme; Kidney; Nitric Oxide Synthase; Protein Conformation; Rats; Recombinant Proteins; Thermodynamics; Thiourea; Transfection | 1995 |
Synthesis of L-thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline: a new class of potent nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Aminocaproates; Aminocaproic Acid; Animals; Binding Sites; Brain; Citrulline; Heme; Iron; Muscle, Smooth; Nitric Oxide Synthase; Rats; Thiourea | 1994 |
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Carbon Monoxide; Cerebellum; Citrulline; Cyanides; Heme; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxyhemoglobins; Rats; Sulfhydryl Compounds; Superoxide Dismutase | 1994 |
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding Sites; Citrulline; Cytochrome c Group; Heme; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thiourea | 1994 |
Characterization of the inactivation of nitric oxide synthase by NG-methyl-L-arginine: evidence for heme loss.
Topics: Amino Acid Oxidoreductases; Arginine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Citrulline; Cytochrome P-450 Enzyme System; Enzyme Stability; Heme; Hemeproteins; Hydrogen Peroxide; Isotope Labeling; Nitric Oxide Synthase; omega-N-Methylarginine; Solubility; Spectrophotometry; Tritium | 1994 |
Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Transport; Cells, Cultured; Citrulline; Cloning, Molecular; Electrons; Heme; Humans; Iron; Kinetics; NADP; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidation-Reduction; Rats; Thiourea | 1994 |
Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Catalysis; Citrulline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Isoenzymes; Male; Microsomes, Liver; Molecular Sequence Data; Nitric Oxide Synthase; Nitrogen Oxides; Oxidation-Reduction; Rats | 1993 |
Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin.
Topics: Animals; Arginine; Binding Sites; Biopterins; Brain; Chromatography, Gel; Circular Dichroism; Citrulline; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Isoenzymes; Light; Macromolecular Substances; Neurons; Nitric Oxide Synthase; Nitroarginine; Protein Conformation; Protein Structure, Secondary; Rats; Scattering, Radiation; Thermodynamics | 1996 |
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding.
Topics: Animals; Arginine; Baculoviridae; Biopterins; Brain; Citrulline; Culture Media; Flavins; Heme; Kinetics; Neurons; Nitric Oxide Synthase; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Spodoptera; Tritium | 1996 |
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats | 1996 |
Interactions between substrate analogues and heme ligands in nitric oxide synthase.
Topics: Animals; Binding Sites; Brain; Carbon Monoxide; Citrulline; Cytochrome P-450 Enzyme System; Drug Interactions; Heme; Ligands; Nitric Oxide Synthase; Protein Conformation; Rats; Spectrum Analysis, Raman; Substrate Specificity | 1997 |
Nitric oxide and proteoglycan turnover in rabbit articular cartilage.
Topics: Animals; Cartilage, Articular; Citrulline; Enzyme Inhibitors; Heme; Interleukin-1; Metalloendopeptidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Proteoglycans; Rabbits; Superoxides; Thiourea | 1997 |
Effects of pH on the structure and function of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Biopterins; Brain; Citrulline; Dimerization; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; NADP; Nerve Tissue Proteins; Nitric Oxide Synthase; Protein Binding; Protein Conformation; Rats; Spectrophotometry | 1998 |
Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase.
Topics: Arginine; Citrulline; Enzyme Inhibitors; Heme; Isoenzymes; NADPH Oxidases; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Structure-Activity Relationship | 1999 |
Inhibition of neuronal nitric oxide synthase by phosphatidylinositol 4,5-bisphosphate and phosphatidic acid.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Catalytic Domain; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; In Vitro Techniques; Kinetics; Mice; Molecular Sequence Data; NADPH Dehydrogenase; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Recombinant Proteins; Sequence Homology, Amino Acid | 1999 |
Reaction of neuronal nitric oxide synthase with the nitric oxide spin-trapping agent, iron complexed with N-dithiocarboxysarcosine.
Topics: Animals; Arginine; Citrulline; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Inhibitors; Ferric Compounds; Heme; In Vitro Techniques; Iron; Mice; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Spin Labels; Swine; Thiocarbamates | 1999 |
Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions.
Topics: Animals; Arginine; Catalysis; Citrulline; Ferrous Compounds; Heme; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Oxygen; Rats; Spectrophotometry | 2000 |
Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin.
Topics: Animals; Arginine; Biopterins; Catalase; Catalysis; Cattle; Citrulline; Dimerization; Free Radical Scavengers; Guanylate Cyclase; Heme; Hydrogen Peroxide; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Pteridines; Rats; Superoxide Dismutase; Superoxides | 2000 |
Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism.
Topics: Arginine; Biopterins; Catalysis; Citrulline; Heme; Hydrogen Peroxide; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction | 2000 |
A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Citrulline; Cloning, Molecular; Escherichia coli; Heme; Kinetics; Models, Chemical; Models, Theoretical; Mutagenesis, Site-Directed; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Recombinant Proteins | 2001 |
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans.
Topics: Amino Acid Sequence; Animals; Arginine; Biopterins; Catalysis; Citrulline; Cloning, Molecular; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Electrons; Heme; Hydrogen Peroxide; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; NADP; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thermus; Time Factors; Zinc | 2002 |
Perferryl complex of nitric oxide synthase: role in secondary free radical formation.
Topics: Arginine; Binding Sites; Carbon Radioisotopes; Citrulline; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Heme; Humans; Iron; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Potassium Compounds; Recombinant Proteins; Sodium Cyanide; Spin Trapping; Sulfates | 2002 |
The antithyroid agent 6-n-propyl-2-thiouracil is a mechanism-based inactivator of the neuronal nitric oxide synthase isoform.
Topics: Animals; Antithyroid Agents; Arginine; Biopterins; Calcium; Calmodulin; Carbon Monoxide; Carbon Radioisotopes; Citrulline; Enzyme Activation; Enzyme Inhibitors; Heme; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pituitary Neoplasms; Propylthiouracil; Rats; Thiouracil; Tumor Cells, Cultured | 2002 |
A density functional theory investigation on the mechanism of the second half-reaction of nitric oxide synthase.
Topics: Arginine; Binding Sites; Citrulline; Computer Simulation; Heme; Models, Chemical; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen; Quantum Theory | 2008 |
The second step of the nitric oxide synthase reaction: evidence for ferric-peroxo as the active oxidant.
Topics: Catalysis; Catalytic Domain; Citrulline; Ferric Compounds; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Nitric Oxide Synthase Type II; Oxidation-Reduction; Peroxides | 2009 |
EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.
Topics: Arginine; Bacterial Proteins; Catalytic Domain; Citrulline; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Geobacillus stearothermophilus; Heme; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction | 2009 |
Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.
Topics: Animals; Arginine; Binding Sites; Catalytic Domain; Citrulline; Enzyme Activation; Guanidine; Heme; Hydrogen Bonding; Mice; Models, Molecular; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Reactive Nitrogen Species; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2010 |
Spectroscopic, catalytic and binding properties of Bacillus subtilis NO synthase-like protein: comparison with other bacterial and mammalian NO synthases.
Topics: Animals; Arginine; Bacillus subtilis; Bacteria; Bacterial Proteins; Binding Sites; Biocatalysis; Biopterins; Citrulline; Ferric Compounds; Ferrous Compounds; Heme; Hydrogen Peroxide; Imidazoles; Kinetics; Mammals; Nitric Oxide Synthase; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Species Specificity; Spectrophotometry | 2012 |