heme has been researched along with 1,2,4-trioxane in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Charman, SA; Chollet, J; Creek, DJ; Dong, Y; Dussault, PH; Scheurer, C; Schiaffo, CE; Vennerstrom, JL; Wang, X; Wittlin, S; Wood, JK | 1 |
| Meunier, B; Robert, A | 1 |
| Gupta, AK; Saxena, AK | 1 |
| Anderson, D; Charman, SA; Creek, DJ; Giannangelo, C; Vennerstrom, JL; Wang, X | 1 |
1 review(s) available for heme and 1,2,4-trioxane
| Article | Year |
|---|---|
Heme as trigger and target for trioxane-containing antimalarial drugs.
Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Heme; Heterocyclic Compounds; Humans; Plasmodium | 2010 |
3 other study(ies) available for heme and 1,2,4-trioxane
| Article | Year |
|---|---|
Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity.
Topics: Alkylation; Animals; Antimalarials; Computer Simulation; Ferric Compounds; Ferrous Compounds; Heme; Heterocyclic Compounds; Mice; Parasitic Sensitivity Tests; Peroxides | 2009 |
Molecular modelling based target identification for endo-peroxides class of antimalarials.
Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Drug Design; Heme; Heterocyclic Compounds; Humans; Malaria, Falciparum; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Plasmodium falciparum; Sequence Alignment | 2015 |
Ozonide Antimalarials Alkylate Heme in the Malaria Parasite
Topics: Alkylation; Antimalarials; Chromatography, Liquid; Heme; Heterocyclic Compounds; Mass Spectrometry; Molecular Structure; Plasmodium falciparum | 2019 |