helioxanthin has been researched along with arecoline in 1 studies
*Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands. [MeSH]
*Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands. [MeSH]
| Studies (helioxanthin) | Trials (helioxanthin) | Recent Studies (post-2010) (helioxanthin) | Studies (arecoline) | Trials (arecoline) | Recent Studies (post-2010) (arecoline) |
|---|---|---|---|---|---|
| 24 | 0 | 10 | 1,110 | 20 | 271 |
| Protein | Taxonomy | helioxanthin (IC50) | arecoline (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.6 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 1.011 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.9163 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.115 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bau, DT; Hsieh, YL; Hsien, HH; Hsu, HH; Huang, CY; Kuo, WW; Lin, YM; Tu, CC; Velmurugan, BK; Viswanadha, VP | 1 |
1 other study(ies) available for helioxanthin and arecoline
| Article | Year |
|---|---|
Helioxanthin suppresses the cross talk of COX-2/PGE2 and EGFR/ERK pathway to inhibit Arecoline-induced Oral Cancer Cell (T28) proliferation and blocks tumor growth in xenografted nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arecoline; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Dinoprostone; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; G2 Phase Cell Cycle Checkpoints; Heterografts; Lignans; Male; MAP Kinase Signaling System; Mice, Nude; Mouth Neoplasms; Signal Transduction; Transcription Factor AP-1 | 2016 |