hecogenin has been researched along with sapogenins in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.82) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 15 (44.12) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Blunden, G; Cripps, AL | 1 |
| Xu, LX; Zhou, TH | 1 |
| Desole, G; Manconi, V; Moretti, MD; Peana, AT; Pippia, P | 1 |
| Chang, CW; Chao, PD; Kuo, SC; Tsai, PL; Wang, JP | 1 |
| Beneytout, JL; Bianchi, A; Bordji, K; Corbiere, C; Dauça, M; Liagre, B; Netter, P | 1 |
| Jin, JM; Liu, XK; Yang, CR | 1 |
| CHAKRAVARTI, D; CHAKRAVARTI, RN; MITRA, MN | 1 |
| Fuchs, PL; Li, W | 1 |
| de la Puerta, R; García, MD; Quílez, AM; Saenz, MT | 1 |
| Camoutsis, C; Gasparinatou, C; Iakovidou, Z; Mioglou, E; Mourelatos, D; Pairas, G | 1 |
| Camoutsis, C; Pairas, G; Papageorgiou, A; Trafalis, D | 1 |
| Dickinson, RG; Elliot, DJ; Mackenzie, PI; Miners, JO; Rowland, A; Williams, JA | 1 |
| Beneytout, JL; Leger, DY; Liagre, B; Vergne-Salle, P | 1 |
| Bush, D; Doss, GA; Franklin, RB; Vincent, S; Xu, S; Zhu, B | 1 |
| Chen, G; Huang, X; Li, T; Lin, J; Zhang, L; Zhang, Z | 1 |
| Jiménez, C; Poza, JJ; Rodríguez, J | 1 |
| Bernès, S; Fernández-Herrera, MA; Hernández-Linares, MG; Meza-Reyes, S; Montiel-Smith, S; Sandoval-Ramírez, J | 1 |
| He, YQ; Liu, HX; Liu, Y; Lu, YL; Wang, CH; Wang, ZT; Xiong, AZ; Xu, LL; Yang, L; Zhang, BF | 1 |
| Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D | 1 |
| Escobar-Sánchez, ML; Fernández-Herrera, MA; Hernández-Vázquez, JM; López-Dávila, M; López-Muñoz, H; Pinto, BM; Sánchez-Sánchez, L; Sandoval-Ramírez, J | 1 |
| del Río, RE; Farfán, N; López, Y; Morzycki, JW; Rodríguez, L; Santillan, R | 1 |
| Arcanjo Moura, B; Barbosa Filho, JM; de Almeida Leal, LK; de Barros Viana, GS; de Castro Brito, GA; dos Santos e Silva, G; Fragoso de Freitas, AP; Lopes Souto, A; Rios Vasconcelos, E; Santos Cerqueira, G; Silveira Macedo, D; Souccar, C | 1 |
| Escobar-Sánchez, ML; Fernández-Herrera, MA; Hernández-Vázquez, JM; López-Muñoz, H; Pinto, BM; Sánchez-Sánchez, L; Sandoval-Ramírez, J | 1 |
| Boysen, G; Dhakal, IB; Edavana, VK; Kadlubar, S; Penney, R; Williams, S; Yao-Borengasser, A | 1 |
| Chapuis, JC; Herald, DL; Knight, JC; Moser, BR; Pettit, GR; Zheng, X | 1 |
| Fajardo-Ramírez, OR; Gutiérrez-Uribe, JA; Romo-López, I; Santos-Zea, L | 1 |
| Ingawale, DK; Patel, SS | 2 |
| Ebrahim, HY; El Sayed, KA; Elsayed, HE; Haggag, EG; Kamal, AM | 1 |
| Li, RT; Liu, YJ; Song, X; Su, T; Yuan, R; Yuan, YH; Zhang, C | 1 |
| Caron, P; Guillemette, C; Lacombe, L; Lévesque, É; Pouliot, F; Turcotte, V; Vaillancourt, J; Villeneuve, L | 1 |
| Ingawale, DK; Mandlik, SK; Patel, SS | 1 |
| Bai, C; Luo, G; Ren, S; Wu, S; Xiang, H; Zhu, M | 1 |
| Azeredo, FJ; Borges, MADH; Passos, FRS; Quintans, JSS | 1 |
1 review(s) available for hecogenin and sapogenins
| Article | Year |
|---|---|
Hecogenin and its derivates: A pharmacology review.
Topics: Cytokines; Humans; Sapogenins; Saponins; Steroids | 2023 |
33 other study(ies) available for hecogenin and sapogenins
| Article | Year |
|---|---|
A quantitative gas-liquid chromatographic method for the estimation of hecogenin and tigogenin in the leaves, juice and sapogenin concentrates of Agave sisalana.
Topics: Chromatography, Gas; Densitometry; Plants; Regression Analysis; Sapogenins; Spirostans | 1978 |
[Colorimetric method for the determination of hecogenin in Agave americana L. residue].
Topics: China; Colorimetry; Plants, Medicinal; Sapogenins | 1982 |
Anti-inflammatory activity of aqueous extracts and steroidal sapogenins of Agave americana.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Gastric Mucosa; Inflammation; Italy; Male; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Sapogenins; Spirostans; Stomach Ulcer; Water | 1997 |
Constituents and bioactive principles of Polygonum chinensis.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Cholestenones; Dipeptides; Mast Cells; Molecular Structure; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Sapogenins; Spectrum Analysis; Spirostans | 1998 |
Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diosgenin; Drugs, Chinese Herbal; Electrophoresis, Polyacrylamide Gel; Humans; Luciferases; Microscopy, Fluorescence; Models, Chemical; Osteosarcoma; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Sapogenins; Spirostans; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53 | 2003 |
Three new hecogenin glycosides from fermented leaves of Agave americana.
Topics: Agave; Carbohydrate Sequence; Fermentation; Glycosides; Magnaporthe; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Optical Rotation; Phytosterols; Plant Leaves; Sapogenins; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared | 2003 |
Hecogenin as a bye-product of the Indian sisal fibre industry.
Topics: Adrenal Cortex Hormones; Industry; Plants; Sapogenins | 1962 |
Polyphosphoric acid trimethylsilyl ester promoted intramolecular acylation of an olefin by a carboxylic acid: convenient construction of C-18-functionalized delta14-hecogenin acetate.
Topics: Acylation; Alkenes; Carboxylic Acids; Isomerism; Molecular Structure; Phosphoric Acids; Phosphorus Compounds; Polymers; Sapogenins; Siloxanes; Spiro Compounds; Trimethylsilyl Compounds | 2003 |
Phytochemical analysis and anti-allergic study of Agave intermixta Trel. and Cissus sicyoides L.
Topics: Agave; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cissus; Diosgenin; Histamine Release; Male; Mast Cells; Plant Extracts; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Resveratrol; Sapogenins; Stilbenes | 2004 |
Synthesis and cytogenetic studies of structure--biological activity relationship of esters of Hecogenin and aza-homo-Hecogenin with N,N-bis(2-chloroethyl)aminocinnamic acid isomers.
Topics: Antineoplastic Agents, Phytogenic; Aza Compounds; Cell Proliferation; Cinnamates; Esterification; Humans; Isomerism; Lymphocytes; Molecular Structure; Mutagenicity Tests; Nitrogen Mustard Compounds; Sapogenins; Sister Chromatid Exchange; Structure-Activity Relationship | 2005 |
On the formation of 4-[N,N-bis(2-chloroethyl)amino]phenyl acetic acid esters of hecogenin and aza-homo-hecogenin and their antileukemic activity.
Topics: Animals; Antineoplastic Agents; Azasteroids; Drug Screening Assays, Antitumor; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Phenylacetates; Sapogenins; Structure-Activity Relationship | 2005 |
In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction.
Topics: Anticonvulsants; Area Under Curve; Cell Line; Drug Interactions; Enzyme Inhibitors; Fluconazole; Glucuronosyltransferase; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Lamotrigine; Microsomes, Liver; Models, Biological; Recombinant Proteins; Sapogenins; Serum Albumin, Bovine; Triazines; Valproic Acid; Zidovudine | 2006 |
Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and tigogenin is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2.
Topics: Apoptosis; Arthritis, Rheumatoid; Caspase 8; Caspase 9; Cell Death; Cell Proliferation; Cell Shape; Cell Survival; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; Middle Aged; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Sapogenins; Saponins; Spirostans; Synovial Fluid; Up-Regulation | 2007 |
Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes.
Topics: Animals; Central Nervous System Agents; Diclofenac; Glucuronides; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; Midazolam; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sapogenins; Uridine Diphosphate Glucuronic Acid | 2008 |
An improved facile method for extraction and determination of steroidal saponins in Tribulus terrestris by focused microwave-assisted extraction coupled with GC-MS.
Topics: Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Microwaves; Phytosterols; Plants, Medicinal; Sapogenins; Saponins; Spirostans; Tribulus | 2009 |
Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytotoxins; Female; Humans; Inhibitory Concentration 50; Lung Neoplasms; Phenazines; Sapogenins; Spiro Compounds; Steroids; Sterols | 2010 |
Deacylation reactions of 20-acetyl dinorcholanic lactones and 20,23-diacetyl furost-22-enes.
Topics: Acylation; Antineoplastic Agents; Diacetyl; Diosgenin; Hydrazines; Lactones; Microwaves; Models, Molecular; Molecular Structure; Sapogenins; Spirostans; Stereoisomerism; X-Ray Diffraction | 2010 |
Identification of the UDP-glucuronosyltransferase isozyme involved in senecionine glucuronidation in human liver microsomes.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Magnetic Resonance Spectroscopy; Microsomes, Liver; Pyrrolizidine Alkaloids; Recombinant Proteins; Sapogenins; Tandem Mass Spectrometry | 2010 |
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine | 2010 |
Synthesis of 26-hydroxy-22-oxocholestanic frameworks from diosgenin and hecogenin and their in vitro antiproliferative and apoptotic activity on human cervical cancer CaSki cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carbohydrate Sequence; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cholestanols; Diosgenin; DNA Fragmentation; Female; Fibroblasts; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Indoles; Lymphocytes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Sapogenins; Steroids; Structure-Activity Relationship; Uterine Cervical Neoplasms | 2010 |
Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain.
Topics: Acetic Anhydrides; Cholestanes; Crystallography, X-Ray; Cyclopentanes; Diosgenin; Furans; Hydrochloric Acid; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Pyrones; Sapogenins; Spiro Compounds; Spirostans; Stereoisomerism | 2012 |
Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in mice.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Glutathione; Humans; Indomethacin; KATP Channels; Lipid Peroxidation; Male; Mice; Neutrophil Activation; Nitric Oxide; Prostaglandins; Random Allocation; Sapogenins; Stomach; Stomach Ulcer | 2012 |
Synthesis and selective anticancer activity of steroidal glycoconjugates.
Topics: Acetylglucosamine; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Diosgenin; Glycosides; Humans; Sapogenins | 2012 |
Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics.
Topics: Anastrozole; Anticonvulsants; Aromatase Inhibitors; Gene Expression Regulation, Enzymologic; Genotype; Glucuronosyltransferase; Humans; In Vitro Techniques; Inactivation, Metabolic; Lamotrigine; Microsomes, Liver; Nitriles; Polymorphism, Single Nucleotide; Sapogenins; Triazines; Triazoles | 2013 |
The Cephalostatins. 23. Conversion of Hecogenin to a Steroidal 1,6-Dioxaspiro[5.5]nonane Analogue for Cephalostatin 11.
Topics: Alkaloids; Alkanes; Animals; Antineoplastic Agents; Furans; Humans; Molecular Structure; Phenazines; Pyrazines; Sapogenins; Spiro Compounds; Steroids | 2015 |
Fast Centrifugal Partition Chromatography Fractionation of Concentrated Agave (Agave salmiana) Sap to Obtain Saponins with Apoptotic Effect on Colon Cancer Cells.
Topics: Acetone; Agave; Antineoplastic Agents; Apoptosis; Centrifugation; Chemical Fractionation; Chromatography; Colonic Neoplasms; HT29 Cells; Humans; Mass Spectrometry; Plant Extracts; Plant Leaves; Sapogenins; Saponins | 2016 |
Anti-Inflammatory Potential of Hecogenin in Experimental Animals: Possible Involvement of Inflammatory Cytokines and Myeloperoxidase.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colon; Cytokines; Disease Models, Animal; Fluticasone; Inflammation; Mice; Peroxidase; Rats; Rats, Wistar; Sapogenins | 2016 |
Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Mammary Neoplasms, Experimental; MAP Kinase Kinase Kinases; Mice; Mice, Nude; Molecular Structure; Protein Kinase Inhibitors; Sapogenins; Structure-Activity Relationship; Thiosemicarbazones; Tumor Cells, Cultured | 2017 |
Hecogenin exhibits anti-arthritic activity in rats through suppression of pro-inflammatory cytokines in Complete Freund's adjuvant-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cytokines; Female; Freund's Adjuvant; Mice; Rats; Rats, Wistar; Sapogenins | 2018 |
[Study on transformation rules of terrestrosin D in course of Tribuli Fructus stir-frying based on simulated processing technology].
Topics: Chromatography, Liquid; Fruit; Hot Temperature; Phytochemicals; Sapogenins; Tandem Mass Spectrometry; Zygophyllaceae | 2019 |
Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation.
Topics: Androgens; Androstenes; Chromatography, Liquid; Glucuronides; Glucuronosyltransferase; Humans; Liver; Metabolic Networks and Pathways; Microsomes, Liver; Neoplasms; Sapogenins; Steroids; Tandem Mass Spectrometry | 2020 |
Hecogenin and fluticasone combination attenuates TNBS-induced ulcerative colitis in rats via downregulation of pro-inflammatory mediators and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Down-Regulation; Drug Therapy, Combination; Female; Fluticasone; Inflammation Mediators; Male; Mice; Oxidative Stress; Rats; Rats, Wistar; Sapogenins; Trinitrobenzenesulfonic Acid | 2021 |
Synthesis and evaluation of novel thiosemicarbazone and semicarbazone analogs with both anti-proliferative and anti-metastatic activities against triple negative breast cancer.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; G1 Phase Cell Cycle Checkpoints; Human Umbilical Vein Endothelial Cells; Humans; Sapogenins; Thiosemicarbazones; Triple Negative Breast Neoplasms | 2021 |