hc toxin has been researched along with trichostatin a in 10 studies
| Studies (hc toxin) | Trials (hc toxin) | Recent Studies (post-2010) (hc toxin) | Studies (trichostatin a) | Trials (trichostatin a) | Recent Studies (post-2010) (trichostatin a) |
|---|---|---|---|---|---|
| 41 | 0 | 7 | 3,365 | 7 | 1,382 |
| 7 | 0 | 1 | 3,365 | 7 | 1,382 |
| Protein | Taxonomy | hc toxin (IC50) | trichostatin a (IC50) |
|---|---|---|---|
| Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | 0.4 | |
| Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | 0.4 | |
| Chain A, Histone deacetylase 7a | Homo sapiens (human) | 0.3 | |
| Chain A, Histone deacetylase 7a | Homo sapiens (human) | 0.3 | |
| Histone deacetylase 8 | Schistosoma mansoni | 3.62 | |
| Histone deacetylase | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 1 | Mus musculus (house mouse) | 0.0047 | |
| Histone deacetylase 3 | Homo sapiens (human) | 0.3388 | |
| 5-hydroxytryptamine receptor 3A | Cavia porcellus (domestic guinea pig) | 7.69 | |
| Histone deacetylase 3 | Mus musculus (house mouse) | 0.0014 | |
| Plasma kallikrein | Homo sapiens (human) | 0.034 | |
| Integrin beta-3 | Homo sapiens (human) | 0.0263 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.02 | |
| Integrin alpha-IIb | Homo sapiens (human) | 0.0263 | |
| Coagulation factor VII | Homo sapiens (human) | 0.034 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.005 | |
| Vitamin D3 receptor | Homo sapiens (human) | 0.087 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.028 | |
| Tissue factor | Homo sapiens (human) | 0.032 | |
| Adenosine receptor A1 | Bos taurus (cattle) | 0.19 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.005 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.1 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.8532 | |
| Histone deacetylase 2 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.2343 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.5944 | |
| Histone deacetylase 1 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Adenosine receptor A1 | Sus scrofa (pig) | 0.2 | |
| Histone deacetylase | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 4 | Mus musculus (house mouse) | 0.0014 | |
| Polyamine deacetylase HDAC10 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 3 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | 1.2 | |
| Histone deacetylase 7 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 8 | Mus musculus (house mouse) | 0.0207 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.5052 | |
| Histone deacetylase 11 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3475 | |
| HD2 type histone deacetylase HDA106 | Zea mays | 0.006 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.3266 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.5027 | |
| Histone deacetylase 9 | Mus musculus (house mouse) | 0.0014 | |
| Histone deacetylase 7 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 6 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 4 | Rattus norvegicus (Norway rat) | 0.1854 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.4994 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.2559 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.5627 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.5332 | |
| Histone deacetylase | Plasmodium falciparum (malaria parasite P. falciparum) | 0.0006 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.0138 | |
| Histone deacetylase 6 | Mus musculus (house mouse) | 0.0387 | |
| Histone deacetylase 5 | Mus musculus (house mouse) | 0.0107 | |
| Histone deacetylase | Zea mays | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (90.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eling, TE; Ikawa, H; Kamitani, H; Kelavkar, UP; Taniura, S; Watanabe, T | 1 |
| Erdlenbruch, B; Kanbach, K; Monkemeyer, S; Pekrun, A; Reinhardt, D; Rönndahl, G; Witt, O | 1 |
| Cho, MJ; Kim, DK; Min, KN; Sheen, YY | 1 |
| Joung, KE; Kim, DK; Sheen, YY | 1 |
| Bates, SE; Jablonski, SA; Robbins, AR; Robey, R; Sackett, DL; Yen, TJ; Yoda, K | 1 |
| Byers, J; Eichinger, D | 1 |
| Brosch, G; Esposito, M; Loidl, P; Mai, A; Massa, S; Ragno, R; Sbardella, G | 1 |
| Bottoni, P; Brosch, G; Cerbara, I; Loidl, P; Mai, A; Massa, S; Ragno, R; Scatena, R; Valente, S | 1 |
| Altucci, L; Brosch, G; Loidl, P; Mai, A; Massa, S; Nebbioso, A; Pezzi, R; Rotili, D; Scognamiglio, A; Simeoni, S | 1 |
| Bradner, JE; Grachan, ML; Greenberg, EF; Haggarty, SJ; Mazitschek, R; Warnow, T; West, N | 1 |
10 other study(ies) available for hc toxin and trichostatin a
| Article | Year |
|---|---|
Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma.
Topics: Acetylation; Arachidonate 15-Lipoxygenase; Blotting, Northern; Butyrates; Caco-2 Cells; Colorectal Neoplasms; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Peptides, Cyclic; Tumor Cells, Cultured | 2001 |
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.
Topics: Amides; Azacitidine; Benzamides; Butyrates; Enzyme Inhibitors; Fetal Hemoglobin; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Globins; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Hydroxyurea; Imidazoles; K562 Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phenylbutyrates; Pyridines; Vorinostat | 2003 |
Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Growth Inhibitors; Humans; Hydroxamic Acids; Peptides, Cyclic; Receptors, Estrogen | 2004 |
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Antibody Technique; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Peptides, Cyclic; Toxins, Biological | 2004 |
Inhibitors of histone deacetylases alter kinetochore assembly by disrupting pericentromeric heterochromatin.
Topics: Acetylation; Aurora Kinase B; Aurora Kinases; Cell Division; Cell Line, Tumor; Centromere; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Depsipeptides; G2 Phase; Heterochromatin; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Indoles; Kinetochores; Marine Toxins; Methotrexate; Microcystins; Microfilament Proteins; Mitosis; Peptides, Cyclic; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; S Phase; Spindle Apparatus | 2005 |
Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner.
Topics: Acetylation; Animals; Blotting, Western; Butyrates; Colon; Entamoeba histolytica; Fatty Acids, Volatile; Histones; Host-Parasite Interactions; Hydrogen-Ion Concentration; Hydroxamic Acids; Parasitology; Peptides, Cyclic; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Trophozoites | 2008 |
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors.
Topics: Drug Design; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Models, Molecular; Molecular Conformation; Pyrroles | 2001 |
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.
Topics: Acrylamides; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Mice; Models, Molecular; Molecular Conformation; Pyrroles; Structure-Activity Relationship | 2004 |
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.
Topics: Amides; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Differentiation; Drug Screening Assays, Antitumor; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Propane; Pyrroles; Repressor Proteins; Structure-Activity Relationship; U937 Cells; Zea mays | 2005 |
Chemical phylogenetics of histone deacetylases.
Topics: | 2010 |