harmine has been researched along with 4-4--dihydroxybiphenyl* in 2 studies
2 other study(ies) available for harmine and 4-4--dihydroxybiphenyl
| Article | Year |
|---|---|
Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp.
Marine cyanobacteria are noted for their ability to excrete metabolites with biotic properties. This paper focuses on such exometabolites obtained from the culture of the marine filamentous cyanobacterium Geitlerinema sp. strain, their purification and subsequent analyses. By this means the recoveries of the active compounds, a prerequisite for properly determining their concentration, are quantified here for the first time. We demonstrate a new procedure using Amberlite XAD-1180 resin in combination with the eluent isopropanol for extraction of the culture media and gas chromatography as simplified chemical analysis. This procedure reduced necessary bacteria cultivation time (from 150 to 21 days) at low volumes of culture media (300 mL) required for identification of two selected bioactive compounds: 4,4'-dihydroxybiphenyl and harmane. Topics: Biological Products; Biphenyl Compounds; Cyanobacteria; Harmine; Oceans and Seas; Species Specificity; Water Microbiology | 2012 |
Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth.
The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays. Good anticyanobacterial activities (concentrations of 8-80 microg ml(-1)) and moderate antibacterial (16-160 microg ml(-1)) and antifungal (32-40 microg ml(-1)) activities were found for both compounds. The natural function as allelopathic chemicals and a possible applicability as antifouling agents or leads for the development of new antifouling chemicals are discussed. Topics: Anti-Bacterial Agents; Antifungal Agents; Biphenyl Compounds; Carbolines; Cyanobacteria; Harmine; Microbial Sensitivity Tests | 2006 |