harmalol and harmine

harmalol has been researched along with harmine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's5 (18.52)18.2507
2000's9 (33.33)29.6817
2010's8 (29.63)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Deng, Y; Duan, J; Kesuma, D; Qi, RZ; Sim, MM; Song, Y; Teng, SF; Wang, J; Wang, JH1
Dukat, M; Glennon, RA; Grella, B; Herrick-Davis, K; Khorana, N; Purohit, A; Smith, C; Teitler, M1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Jiang, X; Liu, J; Peng, L; Peng, S; Zhang, X; Zhao, M; Zheng, M1
Li, C; Liu, J; Peng, S; Wang, Y; Wu, J; Zhang, X; Zhao, M; Zheng, M1
Changwichit, K; Ingkaninan, K; Khorana, N; Utsintong, M1
Dai, JK; Dan, WJ; Wan, JB1
Aarons, DH; Orzechowski, RF; Rossi, GV1
Dickens, BF; Mak, IT; Tse, SY1
Balón, M; Carmona, C; Hidalgo, J; Muñoz, MA1
Al-Alaf, TA; Ayoub, MT; Rashan, LJ1
Douglas, KT; Hider, RC; Sharma, RK; Walmsley, JF1
Hider, RC; Smart, L; Suleiman, MS1
Smart, L1
Begum, S; Faizi, S; Farnaz, S; Gilani, AH; Saeed, SA; Siddiqui, BS; Siddiqui, S; Simjee, RU; Zia, A1
Cassels, BK; Morello, A; Repetto, Y; Rivas, P1
Chen, CF; Liao, JF; Shi, CC1
Altun, ML; Kartal, M; Kurucu, S1
Ferreira, D; Herath, W; Khan, IA; Mikell, JR1
Arshad, N; Hasnain, S; Hess, M; Zitterl-Eglseer, K1
Abedini, M; Aliasgharpour, M; Fathiazad, F; Movafeghi, A; Omidi, Y1
Abe, A; Yamada, H1
Bonsaii, M; Khalilzadeh, MA; Maali, P; Manouchehri, F; Nafisi, S1
Khalilzadeh, MA; Malekabady, ZM; Nafisi, S1
Benedict, C; Crandall, I; Macmullin, G; Pillai, DR; Shahinas, D1
Cheng, X; Deng, Z; Gong, C; Gu, S; Liu, W; Teng, L; Wang, C; Wang, Z; Zhang, L1
Benavente, F; Gagliardi, LG; Tascón, M; Vizioli, NM1

Reviews

1 review(s) available for harmalol and harmine

ArticleYear
Natural and synthetic β-carboline as a privileged antifungal scaffolds.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Antifungal Agents; Biological Products; Carbolines; Drug Discovery; Female; Humans; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycoses; Protein Binding; Signal Transduction; Structure-Activity Relationship

2022

Other Studies

26 other study(ies) available for harmalol and harmine

ArticleYear
Beta-carbolines as specific inhibitors of cyclin-dependent kinases.
    Bioorganic & medicinal chemistry letters, 2002, Apr-08, Volume: 12, Issue:7

    Topics: Carbolines; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Protein Serine-Threonine Kinases

2002
Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Animals; Binding, Competitive; Carbolines; Cell Line; Humans; Mice; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship

2003
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Amino Acids; Animals; Carbolines; Fibrinolytic Agents; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Swine

2010
A class of novel N-(1-methyl-β-carboline-3-carbonyl)-N'-(aminoacid-acyl)-hydrazines: aromatization leaded design, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: Animals; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Hydrazines; Male; Models, Molecular; Molecular Conformation; Platelet Aggregation; Platelet Aggregation Inhibitors; Quantitative Structure-Activity Relationship; Rats; Swine; Thrombosis

2011
Prospective acetylcholinesterase inhibitory activity of indole and its analogs.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Acetylcholinesterase; Binding Sites; Carbolines; Cholinesterase Inhibitors; Enzyme Activation; Humans; Indoles; Molecular Conformation; Quinolines

2012
Cardiovascular actions of three harmala alkaloids: harmine, harmaline, and harmalol.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:9

    Topics: Alkaloids; Animals; Atropine; Blood Pressure; Dogs; Female; Harmaline; Harmine; Heart Rate; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Myocardial Contraction; Rats; Vagotomy; Vascular Resistance

1977
Antioxidative properties of harmane and beta-carboline alkaloids.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: Animals; Antioxidants; Carbolines; Dose-Response Relationship, Drug; Free Radicals; Harmaline; Harmine; Lipid Peroxidation; Male; Microsomes, Liver; Models, Chemical; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiobarbiturates; Tryptamines

1991
Fluorescence of harmol, harmalol and 2-hydroxycarbazole in concentrated hydroxide solutions.
    Pharmaceutisch weekblad. Scientific edition, 1990, Aug-24, Volume: 12, Issue:4

    Topics: Carbazoles; Harmaline; Harmine; Hydrogen-Ion Concentration; Hydroxides; Potassium; Potassium Compounds; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1990
Synthesis and characterization of novel biologically active platinum(II) and palladium(II) complexes of some beta-carboline alkaloids.
    Journal of inorganic biochemistry, 1990, Volume: 38, Issue:1

    Topics: Alkaloids; Antineoplastic Agents; Antiviral Agents; Carbolines; Harmaline; Harmine; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Organoplatinum Compounds; Palladium; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Tumor Cells, Cultured

1990
Ionization processes of some harmala alkaloids.
    Molecular pharmacology, 1983, Volume: 23, Issue:3

    Topics: Alkaloids; Harmaline; Harmine; Hydrogen-Ion Concentration; Ions; Kinetics; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1983
The effect of harmaline and related harmala alkaloids on ouabain-stimulated contractions of the guinea-pig ileum.
    European journal of pharmacology, 1981, Apr-24, Volume: 71, Issue:1

    Topics: Alkaloids; Animals; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Harmaline; Harmine; Ileum; Muscle Contraction; Muscle, Smooth; Ouabain

1981
Competitive inhibition of sodium-dependent high affinity choline uptake by harmala alkaloids.
    European journal of pharmacology, 1981, Nov-05, Volume: 75, Issue:4

    Topics: Alkaloids; Animals; Binding Sites; Choline; Corpus Striatum; Harmaline; Harmine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Sodium; Synaptosomes

1981
Inhibition of platelet aggregation and arachidonic acid metabolism by B-carboline alkaloids.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Blood Platelets; Harmaline; Harmine; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2

1993
Effects of some beta-carboline alkaloids on intact Trypanosoma cruzi epimastigotes.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1999, Volume: 122, Issue:1

    Topics: Animals; Carbolines; Harmaline; Harmine; Kinetics; Nifurtimox; Oxygen Consumption; Species Specificity; Trypanocidal Agents; Trypanosoma cruzi

1999
Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:3

    Topics: Animals; Aorta, Thoracic; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Harmaline; Harmine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasodilator Agents

2001
HPLC method for the analysis of harmol, harmalol, harmine and harmaline in the seeds of Peganum harmala L.
    Journal of pharmaceutical and biomedical analysis, 2003, Feb-26, Volume: 31, Issue:2

    Topics: Chromatography, High Pressure Liquid; Harmaline; Harmine; Peganum; Reproducibility of Results; Seeds; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2003
Microbial metabolites of harman alkaloids.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:6

    Topics: Biotransformation; Cunninghamella; Harmaline; Harmine; Magnetic Resonance Spectroscopy; Molecular Structure; Rhodotorula

2003
Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Bacteria; Carbolines; Chickens; Drug Resistance; Eukaryota; Harmaline; Harmine; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Peganum; Phytotherapy; Plant Extracts; Plants, Medicinal

2008
Floral nectar composition of Peganum harmala L.
    Natural product research, 2009, Volume: 23, Issue:3

    Topics: Chromatography, High Pressure Liquid; Flowers; Fructose; Glucose; Harmaline; Harmine; Peganum; Sucrose

2009
Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells.
    Anti-cancer drugs, 2009, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Apoptosis; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Enzyme Activation; Fas Ligand Protein; fas Receptor; Harmaline; Harmine; Humans; Lung Neoplasms; Neoplasm Proteins

2009
Beta-carboline alkaloids bind DNA.
    Journal of photochemistry and photobiology. B, Biology, 2010, Aug-02, Volume: 100, Issue:2

    Topics: Animals; Antineoplastic Agents; Binding Sites; Carbolines; Cattle; DNA; Harmaline; Harmine; Intercalating Agents; Nucleic Acid Conformation; Peganum; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared

2010
Interaction of β-carboline alkaloids with RNA.
    DNA and cell biology, 2010, Volume: 29, Issue:12

    Topics: Carbolines; Harmaline; Harmine; Nucleic Acid Conformation; Peganum; Plants, Medicinal; RNA, Fungal

2010
Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Synergism; Harmaline; Harmine; HSP90 Heat-Shock Proteins; Malaria; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Plasmodium berghei; Plasmodium falciparum; Protein Structure, Quaternary; Protein Structure, Tertiary; Surface Plasmon Resonance

2012
Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC-ESI-MS/MS and its application to a pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 85

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Female; Harmaline; Harmine; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013
A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions.
    Drug testing and analysis, 2017, Volume: 9, Issue:4

    Topics: Alkaloids; Carbolines; Electrophoresis, Capillary; Harmaline; Harmine; Limit of Detection; Monoamine Oxidase Inhibitors; Peganum; Plant Extracts; Psychotropic Drugs; Seeds; Time Factors

2017
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