harmaline has been researched along with harmalol in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (10.26) | 18.7374 |
| 1990's | 6 (15.38) | 18.2507 |
| 2000's | 11 (28.21) | 29.6817 |
| 2010's | 15 (38.46) | 24.3611 |
| 2020's | 3 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y; Duan, J; Kesuma, D; Qi, RZ; Sim, MM; Song, Y; Teng, SF; Wang, J; Wang, JH | 1 |
| Dukat, M; Glennon, RA; Grella, B; Herrick-Davis, K; Khorana, N; Purohit, A; Smith, C; Teitler, M | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Jiang, X; Liu, J; Peng, L; Peng, S; Zhang, X; Zhao, M; Zheng, M | 1 |
| Li, C; Liu, J; Peng, S; Wang, Y; Wu, J; Zhang, X; Zhao, M; Zheng, M | 1 |
| Changwichit, K; Ingkaninan, K; Khorana, N; Utsintong, M | 1 |
| Dai, JK; Dan, WJ; Wan, JB | 1 |
| Aarons, DH; Orzechowski, RF; Rossi, GV | 1 |
| Aftab, K; Gilani, AH; Saeed, SA; Suria, A | 1 |
| Dickens, BF; Mak, IT; Tse, SY | 1 |
| Balón, M; Carmona, C; Hidalgo, J; Muñoz, MA | 1 |
| Al-Alaf, TA; Ayoub, MT; Rashan, LJ | 1 |
| Douglas, KT; Hider, RC; Sharma, RK; Walmsley, JF | 1 |
| Hider, RC; Smart, L; Suleiman, MS | 1 |
| Smart, L | 1 |
| Begum, S; Faizi, S; Farnaz, S; Gilani, AH; Saeed, SA; Siddiqui, BS; Siddiqui, S; Simjee, RU; Zia, A | 1 |
| Cassels, BK; Morello, A; Repetto, Y; Rivas, P | 1 |
| Ha, HW; Han, ES; Han, JH; Jang, YY; Kim, DE; Lee, CS | 1 |
| Chen, CF; Liao, JF; Shi, CC | 1 |
| Han, ES; Jang, YY; Kim, DH; Lee, CS | 1 |
| Altun, ML; Kartal, M; Kurucu, S | 1 |
| Ferreira, D; Herath, W; Khan, IA; Mikell, JR | 1 |
| Arshad, N; Hasnain, S; Hess, M; Zitterl-Eglseer, K | 1 |
| Abedini, M; Aliasgharpour, M; Fathiazad, F; Movafeghi, A; Omidi, Y | 1 |
| Abe, A; Yamada, H | 1 |
| Bonsaii, M; Khalilzadeh, MA; Maali, P; Manouchehri, F; Nafisi, S | 1 |
| Khalilzadeh, MA; Malekabady, ZM; Nafisi, S | 1 |
| Kim, YH; Lee, SJ; Park, G; Park, SY | 1 |
| Denison, MS; El Gendy, MA; El-Kadi, AO; Soshilov, AA | 1 |
| Benedict, C; Crandall, I; Macmullin, G; Pillai, DR; Shahinas, D | 1 |
| Cheng, X; Deng, Z; Gong, C; Gu, S; Liu, W; Teng, L; Wang, C; Wang, Z; Zhang, L | 1 |
| Bhadra, K; Sarkar, S | 2 |
| Bhadra, K; Pandya, P; Sarkar, S | 1 |
| Bhadra, K; Bhattacharjee, P; Pandya, P; Sarkar, S | 1 |
| Benavente, F; Gagliardi, LG; Tascón, M; Vizioli, NM | 1 |
| Bhadra, K; Bhattacharjee, P; Sarkar, S | 1 |
| Adami, V; Astolfi, A; Barreca, ML; Biasini, E; Biggi, S; Bonetto, V; Dalle Vedove, A; Gatto, P; Lolli, G; Luotti, S; Massignan, T; Pancher, M; Stincardini, C | 1 |
| Cabrerizo, FM; Crovetto, L; Denofrio, MP; Giron, MD; Paredes, JM; Salto, R; Talavera, EM; Yañuk, JG | 1 |
2 review(s) available for harmaline and harmalol
| Article | Year |
|---|---|
Natural and synthetic β-carboline as a privileged antifungal scaffolds.
Topics: Animals; Antifungal Agents; Biological Products; Carbolines; Drug Discovery; Female; Humans; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycoses; Protein Binding; Signal Transduction; Structure-Activity Relationship | 2022 |
Therapeutic Role of Harmalol Targeting Nucleic Acids: Biophysical Perspective and in vitro Cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biophysical Phenomena; Calorimetry; Cell Line, Tumor; Circular Dichroism; DNA Fragmentation; Drug Screening Assays, Antitumor; Harmaline; Humans; Membrane Potential, Mitochondrial; Nucleic Acids; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Viscosity | 2018 |
37 other study(ies) available for harmaline and harmalol
| Article | Year |
|---|---|
Beta-carbolines as specific inhibitors of cyclin-dependent kinases.
Topics: Carbolines; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Protein Serine-Threonine Kinases | 2002 |
Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.
Topics: Animals; Binding, Competitive; Carbolines; Cell Line; Humans; Mice; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship | 2003 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.
Topics: Amino Acids; Animals; Carbolines; Fibrinolytic Agents; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Swine | 2010 |
A class of novel N-(1-methyl-β-carboline-3-carbonyl)-N'-(aminoacid-acyl)-hydrazines: aromatization leaded design, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
Topics: Animals; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Hydrazines; Male; Models, Molecular; Molecular Conformation; Platelet Aggregation; Platelet Aggregation Inhibitors; Quantitative Structure-Activity Relationship; Rats; Swine; Thrombosis | 2011 |
Prospective acetylcholinesterase inhibitory activity of indole and its analogs.
Topics: Acetylcholinesterase; Binding Sites; Carbolines; Cholinesterase Inhibitors; Enzyme Activation; Humans; Indoles; Molecular Conformation; Quinolines | 2012 |
Cardiovascular actions of three harmala alkaloids: harmine, harmaline, and harmalol.
Topics: Alkaloids; Animals; Atropine; Blood Pressure; Dogs; Female; Harmaline; Harmine; Heart Rate; Hemodynamics; Hindlimb; In Vitro Techniques; Male; Myocardial Contraction; Rats; Vagotomy; Vascular Resistance | 1977 |
Effect of harmalol on blood pressure in anaesthetized rats.
Topics: Acetylcholine; Anesthesia; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Harmaline; Heart Rate; Injections, Intravenous; Male; Rats; Rats, Wistar | 1992 |
Antioxidative properties of harmane and beta-carboline alkaloids.
Topics: Animals; Antioxidants; Carbolines; Dose-Response Relationship, Drug; Free Radicals; Harmaline; Harmine; Lipid Peroxidation; Male; Microsomes, Liver; Models, Chemical; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiobarbiturates; Tryptamines | 1991 |
Fluorescence of harmol, harmalol and 2-hydroxycarbazole in concentrated hydroxide solutions.
Topics: Carbazoles; Harmaline; Harmine; Hydrogen-Ion Concentration; Hydroxides; Potassium; Potassium Compounds; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1990 |
Synthesis and characterization of novel biologically active platinum(II) and palladium(II) complexes of some beta-carboline alkaloids.
Topics: Alkaloids; Antineoplastic Agents; Antiviral Agents; Carbolines; Harmaline; Harmine; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Organoplatinum Compounds; Palladium; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Tumor Cells, Cultured | 1990 |
Ionization processes of some harmala alkaloids.
Topics: Alkaloids; Harmaline; Harmine; Hydrogen-Ion Concentration; Ions; Kinetics; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1983 |
The effect of harmaline and related harmala alkaloids on ouabain-stimulated contractions of the guinea-pig ileum.
Topics: Alkaloids; Animals; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Harmaline; Harmine; Ileum; Muscle Contraction; Muscle, Smooth; Ouabain | 1981 |
Competitive inhibition of sodium-dependent high affinity choline uptake by harmala alkaloids.
Topics: Alkaloids; Animals; Binding Sites; Choline; Corpus Striatum; Harmaline; Harmine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Sodium; Synaptosomes | 1981 |
Inhibition of platelet aggregation and arachidonic acid metabolism by B-carboline alkaloids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Blood Platelets; Harmaline; Harmine; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2 | 1993 |
Effects of some beta-carboline alkaloids on intact Trypanosoma cruzi epimastigotes.
Topics: Animals; Carbolines; Harmaline; Harmine; Kinetics; Nifurtimox; Oxygen Consumption; Species Specificity; Trypanocidal Agents; Trypanosoma cruzi | 1999 |
Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Electron Transport; Free Radical Scavengers; Harmaline; Intracellular Membranes; Lipid Peroxidation; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Mitochondria; MPTP Poisoning; Neuroprotective Agents; PC12 Cells; Rats | 2000 |
Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro.
Topics: Animals; Aorta, Thoracic; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Harmaline; Harmine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasodilator Agents | 2001 |
Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells.
Topics: Animals; Brain; Calcium; Cell Survival; Deoxyribose; Dopamine; Harmaline; Intracellular Membranes; Mitochondria; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Oxidopamine; PC12 Cells; Permeability; Proteins; Rats; Sulfhydryl Compounds; Synaptosomes; Thioredoxin-Disulfide Reductase | 2001 |
HPLC method for the analysis of harmol, harmalol, harmine and harmaline in the seeds of Peganum harmala L.
Topics: Chromatography, High Pressure Liquid; Harmaline; Harmine; Peganum; Reproducibility of Results; Seeds; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2003 |
Microbial metabolites of harman alkaloids.
Topics: Biotransformation; Cunninghamella; Harmaline; Harmine; Magnetic Resonance Spectroscopy; Molecular Structure; Rhodotorula | 2003 |
Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Bacteria; Carbolines; Chickens; Drug Resistance; Eukaryota; Harmaline; Harmine; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Peganum; Phytotherapy; Plant Extracts; Plants, Medicinal | 2008 |
Floral nectar composition of Peganum harmala L.
Topics: Chromatography, High Pressure Liquid; Flowers; Fructose; Glucose; Harmaline; Harmine; Peganum; Sucrose | 2009 |
Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells.
Topics: Adenocarcinoma; Apoptosis; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Enzyme Activation; Fas Ligand Protein; fas Receptor; Harmaline; Harmine; Humans; Lung Neoplasms; Neoplasm Proteins | 2009 |
Beta-carboline alkaloids bind DNA.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carbolines; Cattle; DNA; Harmaline; Harmine; Intercalating Agents; Nucleic Acid Conformation; Peganum; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2010 |
Interaction of β-carboline alkaloids with RNA.
Topics: Carbolines; Harmaline; Harmine; Nucleic Acid Conformation; Peganum; Plants, Medicinal; RNA, Fungal | 2010 |
Beta-carboline alkaloids harmaline and harmalol induce melanogenesis through p38 mitogen-activated protein kinase in B16F10 mouse melanoma cells.
Topics: Animals; Cell Differentiation; Harmaline; Intramolecular Oxidoreductases; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Oxidoreductases; p38 Mitogen-Activated Protein Kinases; Phosphorylation | 2010 |
Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms.
Topics: Cytochrome P-450 CYP1A1; Dioxins; Gene Expression Regulation, Enzymologic; Harmaline; Hep G2 Cells; Humans; Molecular Structure; Polychlorinated Dibenzodioxins; Protein Processing, Post-Translational; Receptors, Aryl Hydrocarbon; Transcription, Genetic | 2012 |
Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Synergism; Harmaline; Harmine; HSP90 Heat-Shock Proteins; Malaria; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Plasmodium berghei; Plasmodium falciparum; Protein Structure, Quaternary; Protein Structure, Tertiary; Surface Plasmon Resonance | 2012 |
Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC-ESI-MS/MS and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Female; Harmaline; Harmine; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Binding of alkaloid harmalol to DNA: photophysical and calorimetric approach.
Topics: Calorimetry; Circular Dichroism; DNA; Harmaline; Hydrogen-Ion Concentration; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2014 |
Sequence specific binding of beta carboline alkaloid harmalol with deoxyribonucleotides: binding heterogeneity, conformational, thermodynamic and cytotoxic aspects.
Topics: Cell Line, Tumor; Circular Dichroism; Harmaline; Humans; Molecular Conformation | 2014 |
Targeting different RNA motifs by beta carboline alkaloid, harmalol: a comparative photophysical, calorimetric, and molecular docking approach.
Topics: Alkaloids; Calorimetry; Carbolines; Harmaline; Molecular Conformation; Molecular Docking Simulation; Molecular Structure; Nucleotide Motifs; Osmolar Concentration; RNA; Spectrum Analysis | 2016 |
A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions.
Topics: Alkaloids; Carbolines; Electrophoresis, Capillary; Harmaline; Harmine; Limit of Detection; Monoamine Oxidase Inhibitors; Peganum; Plant Extracts; Psychotropic Drugs; Seeds; Time Factors | 2017 |
DNA binding and apoptotic induction ability of harmalol in HepG2: Biophysical and biochemical approaches.
Topics: Acetylcysteine; Annexin A5; Apoptosis; Biomarkers; Biophysical Phenomena; Caspase 3; Cell Cycle Checkpoints; Cell Shape; Comet Assay; DNA; DNA Damage; DNA Fragmentation; Flow Cytometry; Fluorescein-5-isothiocyanate; Harmaline; Hep G2 Cells; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Mitochondria; Nucleic Acid Conformation; Propidium; Reactive Oxygen Species; Transition Temperature; Tumor Suppressor Protein p53 | 2016 |
Identification of compounds inhibiting prion replication and toxicity by removing PrP
Topics: Animals; Casein Kinase II; Cell Line, Tumor; Cell Membrane; Cell Survival; Drug Evaluation, Preclinical; Fluorescent Dyes; Gene Expression; Green Fluorescent Proteins; Harmaline; HEK293 Cells; Hematoxylin; Humans; Mice; Neuroblastoma; Prions; PrPC Proteins; Quinacrine; Tacrolimus | 2020 |
Photosensitizing properties and subcellular localisation of 3,4-dihydro-β-carbolines harmaline and harmalol.
Topics: Alkaloids; Carbolines; DNA; Harmaline | 2023 |