halothane and sotalol

halothane has been researched along with sotalol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's8 (53.33)29.6817
2010's4 (26.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Bergamaschi, M; Caravaggi, AM; Mandelli, V; Shanks, RG1
Awaji, T; Haruno, A; Hashimoto, K; Hirasawa, A; Wu, Z; Xue, Y1
Antzelevitch, C; Nesterenko, VV; Weissenburger, J1
Hashimoto, K; Sugiyama, A; Takahara, A2
Akie, Y; Hashimoto, K; Sakaguchi, Y; Sugiyama, A; Takahara, A; Takao, S1
Ito, S; Kimura, K; Nakamura, M; Tabo, M1
Ishizaka, T; Iwasaki, H; Kise, H; Mitsumori, Y; Nakamura, Y; Sugiyama, A; Takahara, A1
Akie, Y; Nakamura, Y; Sakaguchi, Y; Sugiyama, A; Takahara, A1
Ando, K; Cao, X; Honda, A; Izumi-Nakaseko, H; Katagi, J; Nakamura, Y; Ohara, H; Sugiyama, A1
Akie, Y; Ando, K; Hoshiai, K; Izumi-Nakaseko, H; Nagayama, Y; Nakamura, Y; Saito, H; Sugiyama, A; Wada, T; Yokoyama, H1
Akie, Y; Goto, A; Hagiwara-Nagasawa, M; Hoshiai, K; Izumi-Nakaseko, H; Kambayashi, R; Kawai, S; Matsumoto, A; Nunoi, Y; Saito, H; Sugiyama, A; Takei, Y1

Other Studies

15 other study(ies) available for halothane and sotalol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
The role of beta adrenoceptors in the coronary and systemic hemodynamic responses to emotional stress in conscious dogs.
    American heart journal, 1973, Volume: 86, Issue:2

    Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Acids; Anesthesia, Intravenous; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Catheterization; Coronary Circulation; Dogs; Electrocardiography; Emotions; Halothane; Heart Rate; Hemodynamics; Humans; Propranolol; Propylamines; Receptors, Adrenergic; Respiration, Artificial; Sotalol; Stress, Psychological; Thiopental

1973
Effects of the new class III antiarrhythmic drug MS-551 and d-sotalol on canine coronary ligation-reperfusion ventricular arrhythmias.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Female; Halothane; Ligation; Male; Myocardial Reperfusion; Pentobarbital; Pyrimidinones; Sotalol; Ventricular Fibrillation

1995
Transmural heterogeneity of ventricular repolarization under baseline and long QT conditions in the canine heart in vivo: torsades de pointes develops with halothane but not pentobarbital anesthesia.
    Journal of cardiovascular electrophysiology, 2000, Volume: 11, Issue:3

    Topics: Action Potentials; Anesthesia, General; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Drug Interactions; Electrocardiography; Female; Halothane; Heart Rate; Heart Ventricles; Hypnotics and Sedatives; Long QT Syndrome; Male; Myocardium; Pentobarbital; Sotalol; Torsades de Pointes

2000
Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
    British journal of pharmacology, 2005, Volume: 146, Issue:4

    Topics: Action Potentials; Adrenergic beta-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Chromans; Delayed Rectifier Potassium Channels; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Electrocardiography; Guinea Pigs; Halothane; Heart; Heart Conduction System; Heart Ventricles; Histamine H1 Antagonists; Linear Models; Long QT Syndrome; Male; Models, Animal; Pharmaceutical Preparations; Potassium Channel Blockers; Reproducibility of Results; Sotalol; Sulfonamides; Terfenadine; Time Factors

2005
Halothane sensitizes the guinea-pig heart to pharmacological IKr blockade: comparison with urethane anesthesia.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:2

    Topics: Action Potentials; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Chromans; Delayed Rectifier Potassium Channels; Drug Evaluation, Preclinical; Electrocardiography; Guinea Pigs; Halothane; Heart Rate; Male; Potassium; Potassium Channel Blockers; Sotalol; Sulfonamides; Time Factors; Urethane

2005
Characterization of the halothane-anesthetized guinea-pig heart as a model to detect the K+ channel blocker-induced QT-interval prolongation.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Chromans; Electrocardiography; Guinea Pigs; Halothane; Heart; Heart Rate; Long QT Syndrome; Male; Potassium Channel Blockers; Sotalol; Sulfonamides

2006
QT-RR relationships and suitable QT correction formulas for halothane-anesthetized dogs.
    The Journal of toxicological sciences, 2006, Volume: 31, Issue:4

    Topics: Analysis of Variance; Anesthesia; Animals; Astemizole; Dogs; Electrocardiography; Halothane; Male; Propranolol; Sotalol

2006
Comparison of electropharmacological effects of bepridil and sotalol in halothane-anesthetized dogs.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:6

    Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Atrioventricular Node; Bepridil; Bundle of His; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Halothane; Heart Conduction System; Male; Models, Animal; Myocardial Contraction; Pacemaker, Artificial; Sinoatrial Node; Sotalol; Vasodilator Agents

2008
Halothane-anaesthetized, closed-chest, guinea-pig model for assessment of drug-induced QT-interval prolongation.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Electrocardiography; Guinea Pigs; Halothane; Heart; Heart Rate; Long QT Syndrome; Male; Models, Animal; Sotalol; Verapamil

2009
Why Can dl-Sotalol Prolong the QT Interval In Vivo Despite Its Weak Inhibitory Effect on hERG K(+) Channels In Vitro? Electrophysiological and Pharmacokinetic Analysis with the Halothane-Anesthetized Guinea Pig Model.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electrocardiography; ERG1 Potassium Channel; Guinea Pigs; Halothane; Heart Rate; Male; Models, Animal; Sotalol

2016
Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Electrocardiography; Halothane; Long QT Syndrome; Male; Models, Animal; Sotalol; Swine; Swine, Miniature; Toxicity Tests

2017
In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state.
    Journal of pharmacological sciences, 2021, Volume: 145, Issue:1

    Topics: Anesthesia; Animals; Consciousness; Dogs; Electrocardiography; Halothane; Isoflurane; Male; Nitrous Oxide; Sotalol

2021