halothane and ryanodine

halothane has been researched along with ryanodine in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (8.16)	18.7374
1990's	32 (65.31)	18.2507
2000's	13 (26.53)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Endo, M; Iino, M; Kawana, Y; Oyamada, H	1
Connelly, TJ; Coronado, R; Hayek, RE; Rusy, BF	1
Carrier, L; Dupont, Y; Villaz, M	1
Nelson, TE	1
Beech, J; Fletcher, JE; Rosenberg, H	1
Ellis, FR; Halsall, PJ; Hopkins, PM	2
Lynch, C	1
Komai, H; Rusy, BF	2
Berman, MR; Blanck, TJ; Casella, ES	1
Palade, P	1
DeTraglia, MC; Komai, H; Redon, D; Rusy, BF	1
Gallant, EM; Jacobson, BA; Johnson, KM; Litterer, LA; Louis, CF; Mickelson, JR; Rempel, WE	1
Fairhurst, AS; Hamamoto, V; Macri, J	1
Lynch, C; Pancrazio, JJ	1
Becker, K; Köchling, A; Lenzen, C; Roewer, N; Scholz, J; Schulte am Esch, J; Singh, S; Steinfath, M; Wappler, F	1
Fujita, S; Namba, H; Namiki, A; Notsuki, E; Tsuchida, H; Yamakage, M	1
Deufel, T; Du Chesne, I; Feist, Y; Grimm, T; Hartung, EJ; Lehmann-Horn, F; Roewer, N; Rübsam, B; Schäfer, KL; Sudbrak, R	1
Boyle, WA; Maher, GM	1
Bosnjak, ZJ; Hogan, QH; Kampine, JP; Stadnicka, A; Stekiel, TA	1
Akata, T; Boyle, WA	1
Hatano, Y; Kakuyama, M; Mori, K; Nakamura, K; Nishiwada, M; Terasako, K; Toda, H	1
Heinroth, K; Hoffmann, P; Plews, P; Richards, D; Toraason, M	1
Lenzen, C; Roewer, N; Rumberger, R; Scholz, J; Schulte am Esch, J; Steinfath, M; Wappler, F	1
Lynch, C; Miao, N	1
Akata, T; Boyle, W	1
Anetseder, M; Engelhardt, W; Hartung, E; Hogrefe, G; Koob, M; Krauspe, R; Schoemig, P	1
Fujihara, H; Fujiwara, N; Fukuda, S; Shimoji, K	1
Ellis, FR; Halsall, PJ; Hopkins, PM; Stewart, AD	1
Fuentes, E; McNaughton, PA; Nadal, A; Pastor, J	1
Owen, JB; Treasure, JL	1
Bendixen, D; Fagerlund, T; Gardi, T; Glahn, K; Ording, H	1
Jiang, Y; Julian, FJ	1
Adnet, PJ; Fletcher, JE; Reyford, H; Rosenberg, H; Stewart, SL; Wieland, SJ	1
Boyett, MR; Davies, LA; Hamilton, DL; Harrison, SM; Hopkins, PM	1
Descorps-Declère, A; Frizelle, HP; Mazoit, JX; Sauviat, MP	1
am Esch, JS; Krause, T; Martens, U; Scholz, J; Steinrücke, K; Wappler, F	1
Agarwal, K; Fiege, M; Matschke, J; Scholz, J; Schulte Am Esch , J; Singh, S; Steinfath, M; Wappler, F	1
Prakash, YS; Seckin, I; Sieck, GC	1
Braun, V; Greiser, M; Hanrath, P; Karlein, C; Schoendube, F; Schotten, U	1
Barbosa, J; Gomez, MV; Gomez, RS; Guatimosim, C; Massensini, AR; Prado, MA	1
Brooks, C; Brown, SL; Ellis, FR; Halsall, PJ; Hopkins, PM; Quinnell, RJ; Robinson, RL; Shaw, MA	1
Censier, K; Ginz, HF; Girard, T; Urwyler, A	1
Bendahan, D; Cozzone, PJ; Ghattas, B; Guis, S; Kozak-Ribbens, G; Lunardi, J; Mattei, JP; Monnier, N	1
Duke, AM; Halsal, JP; Hopkins, PM; Steele, DS	1
Gerbershagen, MU; Wappler, F	1
Allen, PD; Esteve, E; Goth, S; Lopez, JR; Matthaei, KI; Pessah, IN; Riehl, J; Yang, T	1
Bina, S; Bünger, R; Muldoon, S	1

Reviews

1 review(s) available for halothane and ryanodine

Article	Year
Intriguing links between animal behavior and anorexia nervosa. The International journal of eating disorders, 1997, Volume: 21, Issue:4 Topics: Animals; Anorexia Nervosa; Behavior, Animal; Body Composition; Disease Models, Animal; Halothane; Humans; Mutation; Ryanodine; Serotonin; Swine	1997

Other Studies

48 other study(ies) available for halothane and ryanodine

Article	Year
[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells]. Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:5 Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Leukocytes, Mononuclear; Malignant Hyperthermia; Models, Biological; Ryanodine	1992
Volatile anesthetics selectively alter [3H]ryanodine binding to skeletal and cardiac ryanodine receptors. Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1 Topics: Animals; Calcium; Dose-Response Relationship, Drug; Enflurane; Halothane; Isoflurane; Kinetics; Muscles; Myocardium; Receptors, Cholinergic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine; Tritium	1992
Abnormal rapid Ca2+ release from sarcoplasmic reticulum of malignant hyperthermia susceptible pigs. Biochimica et biophysica acta, 1991, May-07, Volume: 1064, Issue:2 Topics: Adenosine Triphosphatases; Animals; Biological Transport; Caffeine; Calcium; Calcium Channels; Filtration; Halothane; Kinetics; Magnesium; Malignant Hyperthermia; Ryanodine; Sarcoplasmic Reticulum; Swine	1991
Effect of halothane on human skeletal muscle sarcoplasmic reticulum calcium-release channel. Advances in experimental medicine and biology, 1991, Volume: 301 Topics: Calcium; Calcium Channels; Halothane; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Muscles; Myocardium; Ryanodine; Sarcoplasmic Reticulum	1991
Interactions of fatty acids with the calcium release channel in malignant hyperthermia. Advances in experimental medicine and biology, 1991, Volume: 301 Topics: Animals; Caffeine; Calcium Channels; Fatty Acids; Halothane; Horses; Humans; Isoproterenol; Lipase; Malignant Hyperthermia; Muscle Proteins; Phenytoin; Ryanodine; Succinylcholine; Swine; Triglycerides	1991
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia. Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781 Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Military Personnel; Muscle Contraction; Muscles; Muscular Diseases; Physical Exertion; Ryanodine	1991
Differential depression of myocardial contractility by volatile anesthetics in vitro: comparison with uncouplers of excitation-contraction coupling. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:4 Topics: Animals; Electric Stimulation; Enflurane; Guinea Pigs; Halothane; Heart; In Vitro Techniques; Isoflurane; Isoproterenol; Myocardial Contraction; Myocardium; Ryanodine; Uncoupling Agents	1990
Contribution of the known subcellular effects of anesthetics to their negative inotropic effect in intact myocardium. Advances in experimental medicine and biology, 1991, Volume: 301 Topics: Anesthetics; Animals; Depression, Chemical; Halothane; In Vitro Techniques; Isoflurane; Myocardial Contraction; Myofibrils; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Subcellular Fractions	1991
Evidence for a halothane-induced reduction in maximal calcium-activated force in mammalian myocardium. Advances in experimental medicine and biology, 1991, Volume: 301 Topics: Actin Cytoskeleton; Animals; Calcium; Depression, Chemical; Electric Stimulation; Halothane; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Rabbits; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum	1991
Direct effect of halothane and isoflurane on the function of the sarcoplasmic reticulum in intact rabbit atria. Anesthesiology, 1990, Volume: 72, Issue:4 Topics: Animals; Calcium; Culture Media; Halothane; Heart; Heart Atria; In Vitro Techniques; Isoflurane; Myocardial Contraction; Myocardium; Osmolar Concentration; Rabbits; Ryanodine; Sarcoplasmic Reticulum	1990
Drug-induced Ca2+ release from isolated sarcoplasmic reticulum. II. Releases involving a Ca2+-induced Ca2+ release channel. The Journal of biological chemistry, 1987, May-05, Volume: 262, Issue:13 Topics: Animals; Caffeine; Calcium; Halothane; Ion Channels; Miconazole; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum; Sulfonamides; Tetracaine; Thymol	1987
Isoflurane and halothane inhibit tetanic contractions in rabbit myocardium in vitro. Anesthesiology, 1989, Volume: 70, Issue:5 Topics: Animals; Calcium; Depression, Chemical; Electric Stimulation; Halothane; In Vitro Techniques; Isoflurane; Myocardial Contraction; Nifedipine; Papillary Muscles; Rabbits; Ryanodine; Sarcoplasmic Reticulum	1989
Effects of the halothane-sensitivity gene on sarcoplasmic reticulum function. The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1 Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Genes; Halothane; Kinetics; Malignant Hyperthermia; Muscles; Receptors, Cholinergic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Species Specificity; Swine; Swine Diseases	1989
Modification of ryanodine toxicity by dantrolene and halothane in a model of malignant hyperthermia. Anesthesiology, 1980, Volume: 53, Issue:3 Topics: Alkaloids; Animals; Dantrolene; Diaphragm; Disease Models, Animal; Halothane; In Vitro Techniques; Male; Malignant Hyperthermia; Mice; Rats; Ryanodine; Succinylcholine	1980
Differential anesthetic-induced opening of calcium-dependent large conductance channels in isolated ventricular myocytes. Pflugers Archiv : European journal of physiology, 1994, Volume: 429, Issue:1 Topics: Anesthetics; Animals; Caffeine; Calcium; Guinea Pigs; Halothane; Heart Ventricles; In Vitro Techniques; Ion Channels; Isoflurane; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Ryanodine; Sarcoplasmic Reticulum	1994
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response. Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:1 Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromosomes, Human, Pair 19; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Point Mutation; Polymorphism, Genetic; Ryanodine; Ryanodine Receptor Calcium Release Channel	1995
Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta. Anesthesiology, 1993, Volume: 78, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Caffeine; Calcium; Calcium Channels; Cytosol; Dose-Response Relationship, Drug; Halothane; Isoflurane; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum	1993
Discordance, in a malignant hyperthermia pedigree, between in vitro contracture-test phenotypes and haplotypes for the MHS1 region on chromosome 19q12-13.2, comprising the C1840T transition in the RYR1 gene. American journal of human genetics, 1995, Volume: 56, Issue:6 Topics: Calcium Channels; Chromosomes, Human, Pair 19; Contracture; Disease Susceptibility; Female; Genetic Linkage; Genetic Markers; Germany; Halothane; Haplotypes; Humans; Male; Malignant Hyperthermia; Models, Genetic; Muscle Proteins; Pedigree; Phenotype; Ryanodine; Ryanodine Receptor Calcium Release Channel	1995
Endothelium-independent vasoconstricting and vasodilating actions of halothane on rat mesenteric resistance blood vessels. Anesthesiology, 1995, Volume: 82, Issue:1 Topics: Animals; Caffeine; Drug Interactions; Endothelium, Vascular; Halothane; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Ryanodine; Vascular Resistance; Vasoconstriction; Vasodilation	1995
Hypoxic contraction of isolated rabbit mesenteric veins. Contribution of endothelium and attenuation by volatile anesthetics. Anesthesiology, 1995, Volume: 82, Issue:2 Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Enflurane; Glycopeptides; Halothane; Hypoxia; In Vitro Techniques; Indomethacin; Isoflurane; Male; Masoprocol; NG-Nitroarginine Methyl Ester; Nicardipine; Norepinephrine; Peptides, Cyclic; Rabbits; Ryanodine; Vasoconstriction	1995
Volatile anesthetic actions on contractile proteins in membrane-permeabilized small mesenteric arteries. Anesthesiology, 1995, Volume: 82, Issue:3 Topics: Animals; Calcium; Cell Membrane Permeability; Contractile Proteins; Enflurane; Escin; Halothane; In Vitro Techniques; Isoflurane; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Rats; Rats, Sprague-Dawley; Ryanodine	1995
Halothane and enflurane constrict canine mesenteric arteries by releasing Ca2+ from intracellular Ca2+ stores. Anesthesiology, 1994, Volume: 80, Issue:5 Topics: Animals; Arginine; Caffeine; Calcium; Dogs; Enflurane; Fluorescent Dyes; Fura-2; Halothane; In Vitro Techniques; Indomethacin; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroarginine; Ryanodine; Spectrometry, Fluorescence; Vasoconstriction	1994
Depression of calcium dynamics in cardiac myocytes--a common mechanism of halogenated hydrocarbon anesthetics and solvents. Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:5 Topics: Anesthetics; Animals; Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Electric Stimulation; Ethylene Dichlorides; Fura-2; Halothane; Heart; Hydrocarbons, Halogenated; Methylene Chloride; Myocardium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Solvents; Spectrometry, Fluorescence; Terpenes; Thapsigargin; Trichloroethylene	1994
[High purity ryanodine for in vitro diagnosis of malignant hyperthermia]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1993, Volume: 28, Issue:7 Topics: Adolescent; Adult; Caffeine; Child; Culture Techniques; Dose-Response Relationship, Drug; Female; Halothane; Humans; Isometric Contraction; Male; Malignant Hyperthermia; Middle Aged; Ryanodine	1993
Effect of temperature on volatile anesthetic depression of myocardial contractions. Anesthesia and analgesia, 1993, Volume: 76, Issue:2 Topics: Animals; Depression, Chemical; Enflurane; Guinea Pigs; Halothane; In Vitro Techniques; Isoflurane; Myocardial Contraction; Nifedipine; Ryanodine; Temperature	1993
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders. British journal of anaesthesia, 1993, Volume: 70, Issue:4 Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Neuromuscular Diseases; Ryanodine	1993
Dual actions of halothane on intracellular calcium stores of vascular smooth muscle. Anesthesiology, 1996, Volume: 84, Issue:3 Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Halothane; Muscle, Smooth, Vascular; Procaine; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum	1996
Malignant hyperthermia (MH) diagnostics: a comparison between the halothane-caffeine- and the ryanodine-contracture-test results in MH susceptible, normal and control muscle. Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:4 Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Ryanodine	1996
The effects of halothane on arginine-vasopressin-induced Ca2+ mobilization from the intracellular stores and the receptor-mediated Ca2+ entry from the extracellular space in single cultured smooth muscle cells of rat aorta. Anesthesia and analgesia, 1996, Volume: 83, Issue:3 Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Arginine Vasopressin; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Extracellular Space; Halothane; Intracellular Fluid; Muscle, Smooth, Vascular; Nicardipine; Rats; Rats, Wistar; Receptors, Cell Surface; Ryanodine; Vasoconstrictor Agents; Vasodilator Agents	1996
An analysis of the predictive probability of the in vitro contracture test for determining susceptibility to malignant hyperthermia. Anesthesia and analgesia, 1997, Volume: 84, Issue:3 Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Probability; Regression Analysis; Ryanodine	1997
Plasma albumin induces calcium waves in rat cortical astrocytes. Glia, 1997, Volume: 19, Issue:4 Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Gap Junctions; Halothane; Inositol 1,4,5-Trisphosphate; Kinetics; Rats; Ryanodine; Serum Albumin, Bovine; Time Factors	1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility. Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8 Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Ryanodine	1997
Effects of halothane on [Ca2+]i transient, SR Ca2+ content, and force in intact rat heart trabeculae. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: Animals; Calcium; Electric Stimulation; Fura-2; Halothane; Heart; In Vitro Techniques; Male; Myocardial Contraction; Rats; Rats, Inbred BN; Rats, Inbred Lew; Ryanodine; Sarcoplasmic Reticulum; Time Factors	1998
ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine. Anesthesiology, 1999, Volume: 90, Issue:5 Topics: Animals; Caffeine; Cnidarian Venoms; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium Channels	1999
Concentration-dependent inotropic effects of halothane, isoflurane and sevoflurane on rat ventricular myocytes. British journal of anaesthesia, 1999, Volume: 82, Issue:5 Topics: Anesthetics, Inhalation; Animals; Cell Culture Techniques; Dose-Response Relationship, Drug; Halothane; Heart; Heart Ventricles; Isoflurane; Methyl Ethers; Myocardial Contraction; Rats; Ryanodine; Sarcoplasmic Reticulum; Sevoflurane	1999
Effects of halothane on the membrane potential in skeletal muscle of the frog. British journal of pharmacology, 2000, Volume: 130, Issue:3 Topics: Anesthetics, Inhalation; Animals; Charybdotoxin; Glyburide; Halothane; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle, Skeletal; Potassium Channels; Rana esculenta; Ryanodine; Tetraethylammonium; Tetrodotoxin	2000
Inositol 1,4,5-trisphosphate synthesis in mononuclear white blood cells of malignant hyperthermia-susceptible and normal human beings, following in vitro exposure to halothane, caffeine and ryanodine. European journal of anaesthesiology, 2000, Volume: 17, Issue:6 Topics: Anesthetics, Inhalation; Caffeine; Cell Separation; Halothane; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Malignant Hyperthermia; Muscle Contraction; Neutrophils; Phosphodiesterase Inhibitors; Respiratory Muscles; Ryanodine	2000
Evidence for susceptibility to malignant hyperthermia in patients with exercise-induced rhabdomyolysis. Anesthesiology, 2001, Volume: 94, Issue:1 Topics: Adolescent; Adult; Anesthetics, Inhalation; Case-Control Studies; Child; Disease Susceptibility; Exercise; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Polymerase Chain Reaction; Rhabdomyolysis; Ryanodine	2001
Volatile anaesthetic effects on Na+-Ca2+ exchange in rat cardiac myocytes. The Journal of physiology, 2001, Apr-01, Volume: 532, Issue:Pt 1 Topics: Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Halothane; Heart; Indoles; Male; Methyl Ethers; Microscopy, Confocal; Myocardium; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum; Sevoflurane; Sodium; Sodium-Calcium Exchanger	2001
Effect of volatile anesthetics on the force-frequency relation in human ventricular myocardium: the role of the sarcoplasmic reticulum calcium-release channel. Anesthesiology, 2001, Volume: 95, Issue:5 Topics: Anesthetics, Inhalation; Calcium Channel Blockers; Calcium Channels; Cardiomyopathies; Culture Techniques; Drug Interactions; Electric Stimulation; Halothane; Humans; Isoflurane; Methyl Ethers; Myocardial Contraction; Myocardium; Ryanodine; Sarcoplasmic Reticulum; Sevoflurane; Vasodilator Agents; Verapamil	2001
Halothane-induced intracellular calcium release in cholinergic cells. Brain research, 2001, Dec-07, Volume: 921, Issue:1-2 Topics: Acetylcholine; Anesthetics, Inhalation; Aniline Compounds; Animals; Brain; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Dantrolene; Enzyme Inhibitors; Extracellular Space; Fluorescent Dyes; Halothane; Humans; Intracellular Fluid; Microscopy, Confocal; Muscle Relaxants, Central; Neurons; Potassium Chloride; Ryanodine; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission; Xanthenes	2001
RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes. Human mutation, 2002, Volume: 20, Issue:2 Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Exons; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle, Skeletal; Mutation; Myopathy, Central Core; Phenotype; Prevalence; Retrospective Studies; Ryanodine; Ryanodine Receptor Calcium Release Channel; United Kingdom	2002
Similar susceptibility to halothane, caffeine and ryanodine in vitro reflects pharmacogenetic variability of malignant hyperthermia. European journal of anaesthesiology, 2004, Volume: 21, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Genetic Predisposition to Disease; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Retrospective Studies; Ryanodine; Time Factors	2004
Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia. Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:8 Topics: Anesthetics, Inhalation; Caffeine; DNA; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Mutation; Phosphodiesterase Inhibitors; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; ROC Curve; Ryanodine	2004
Mg2+ dependence of halothane-induced Ca2+ release from the sarcoplasmic reticulum in skeletal muscle from humans susceptible to malignant hyperthermia. Anesthesiology, 2004, Volume: 101, Issue:6 Topics: Anesthetics, Inhalation; Caffeine; Calcium; Central Nervous System Stimulants; Cytosol; Halothane; Humans; In Vitro Techniques; Magnesium; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Ryanodine; Sarcoplasmic Reticulum	2004
Validity and new malignant hyperthermia diagnostic procedures. Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:1 Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Reproducibility of Results; Ryanodine	2006
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology, 2006, Volume: 105, Issue:6 Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Temperature; Calcium; Cell Line; Cell Membrane; Deoxyribonuclease EcoRI; Diagnostic Imaging; Disease Models, Animal; DNA; Exons; Halothane; Humans; Malignant Hyperthermia; Mice; Mice, Knockout; Microelectrodes; Muscle Fibers, Skeletal; Mutation; Nerve Fibers; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ryanodine; Ryanodine Receptor Calcium Release Channel	2006
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. European journal of anaesthesiology, 2008, Volume: 25, Issue:1 Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Kinetics; Lactates; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Pyruvates; Reference Values; Ryanodine; Ryanodine Receptor Calcium Release Channel; Swine; Swine Diseases	2008