halothane has been researched along with metyrapone in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Akita, S; Fujii, K; Kawahara, M; Morio, M; Takeshita, T; Yamamoto, M | 1 |
| Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H | 1 |
| Rösen, P; Stier, A | 1 |
| Krüger, R; Nastainczyk, W; Rendic, S; Ullrich, V | 1 |
| Farrell, GC; Field, J; Frost, L; Mahoney, J; Tapner, M; Weltman, M | 1 |
6 other study(ies) available for halothane and metyrapone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Halothane-induced liver injury as a consequence of enhanced microsomal lipid peroxidation in guinea pigs.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Glutathione; Guinea Pigs; Halothane; Lipid Peroxides; Liver; Male; Metyrapone; Microsomes, Liver; Rats; Transaminases | 1988 |
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1973 |
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene | 1974 |
[Prevention by metyrapone of halothane induced liver necrosis in rats (author's transl)].
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Halothane; L-Iditol 2-Dehydrogenase; Male; Metyrapone; Necrosis; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains | 1982 |
Halothane-induced liver injury in guinea-pigs: importance of cytochrome P450 enzyme activity and hepatic blood flow.
Topics: Animals; Arteries; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fomepizole; Genetic Predisposition to Disease; Guinea Pigs; Halothane; Liver; Liver Circulation; Male; Metyrapone; Microsomes, Liver; Necrosis; Portal System; Proadifen; Pyrazoles | 1996 |