halothane and metyrapone

halothane has been researched along with metyrapone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Akita, S; Fujii, K; Kawahara, M; Morio, M; Takeshita, T; Yamamoto, M1
Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H1
Rösen, P; Stier, A1
Krüger, R; Nastainczyk, W; Rendic, S; Ullrich, V1
Farrell, GC; Field, J; Frost, L; Mahoney, J; Tapner, M; Weltman, M1

Other Studies

6 other study(ies) available for halothane and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Halothane-induced liver injury as a consequence of enhanced microsomal lipid peroxidation in guinea pigs.
    Research communications in chemical pathology and pharmacology, 1988, Volume: 61, Issue:2

    Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Glutathione; Guinea Pigs; Halothane; Lipid Peroxides; Liver; Male; Metyrapone; Microsomes, Liver; Rats; Transaminases

1988
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:1

    Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites

1973
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene

1974
[Prevention by metyrapone of halothane induced liver necrosis in rats (author's transl)].
    Der Anaesthesist, 1982, Volume: 31, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Halothane; L-Iditol 2-Dehydrogenase; Male; Metyrapone; Necrosis; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains

1982
Halothane-induced liver injury in guinea-pigs: importance of cytochrome P450 enzyme activity and hepatic blood flow.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:6

    Topics: Animals; Arteries; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fomepizole; Genetic Predisposition to Disease; Guinea Pigs; Halothane; Liver; Liver Circulation; Male; Metyrapone; Microsomes, Liver; Necrosis; Portal System; Proadifen; Pyrazoles

1996