halothane and lactic acid

halothane has been researched along with lactic acid in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199012 (32.43)18.7374
1990's13 (35.14)18.2507
2000's10 (27.03)29.6817
2010's2 (5.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Anand, KJ; Hickey, PR1
McLoughlin, JV; Wheatley, AM1
Crystal, GJ; Salem, MR1
Aminalai, A; Bretschneider, HJ; Bürger, E; Gersing, E; Kehrer, G; Mari, A; Meissner, A1
Adams, HA; Hempelmann, G; Michaelis, G; Wolf, C1
Harp, JR; Keykhah, MM; O'Neill, JJ; Smith, DS1
Ahern, CP; Gronert, GA; Milde, JH1
Brown, MJ; Burrin, J; Causon, RC; Hall, GM; Lacoumenta, S; Paterson, JL1
Albrecht, RF; Becker, GL; Hensel, P; Holland, AD; Miletich, DJ1
Fishbein, WN1
Bent, JM; Hall, GM; Mashiter, K; Paterson, JL1
Hall, GM; Lacoumenta, S; Paterson, JL; Walsh, ES; Ward, I; Waterman, AE1
Flewellen, EH; Gloyna, DF; Nelson, TE1
Baer, RW; Fein, G; Hickey, RF; Hoffman, JI; Verrier, ED; Vlahakes, GJ1
Bussell, JA; Gray, RJ; Matloff, JM; Moffitt, EA; Raymond, M; Sethna, DH1
Araki, M; Inaba, H; Mizuguchi, T1
Haljamäe, H; Ricksten, SE; Sahlman, L; Waagstein, L1
Luna, SP; Taylor, PM; Wheeler, MJ1
Araki, M; Imai, M; Inaba, H; Kon, S; Mizuguchi, T1
Luna, SP; Massone, F; Taylor, PM1
Baird, MS; Kirk, KA; McCammon, AT; Nielsen, VG; Parks, DA; Samuelson, PN; Tan, S1
Ferreira, LD; Fournier, PA; Palmer, TN1
Taylor, PM1
Baumane, L; Dzintare, M; Kalvinsh, I; Lauberte, L; Meirena, D; Sile, V; Sjakste, N; Zvejniece, L1
De Hert, S; Degroote, F; Mathieu, N; Schmartz, D; Van der Linden, P; Vincent, JL; Zhang, H1
CLARK, JD; LOWENSTEIN, E; VILLAREAL, Y1
den Hartog, LA; Ducro, BJ; Eissen, JJ; Hambrecht, E; Nooijent, RI; Smits, CH; Verstegen, MW1
Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S1
Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F1
Anetseder, M; Müller, R; Roewer, N; Schuster, F; Tas, P1
Brennan, TJ; Freml, L; Kim, TJ; Park, SS1
DeAnda, A; Gaba, DM; Maxwell, MS; Vickery, R1
Adamson, G; Bell, D; Carmichael, FJ; Crawford, MW; Engelhardt, T; Kim, PC; Shichor, T1
Anetseder, M; Hager, M; Metterlein, T; Muellenbach, RM; Roewer, N; Schuster, F; Wunder, C; Wurmb, T1
Ericzon, BG; Nowak, G; Ungerstedt, J; Ungerstedt, U1
Becker, S; Burmester, S; Gerbershagen, MU; Kröner, L; Lenz, D; Schütte, JK; Starosse, A; Wappler, F1

Trials

5 trial(s) available for halothane and lactic acid

ArticleYear
Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery.
    The New England journal of medicine, 1992, Jan-02, Volume: 326, Issue:1

    Topics: Acetoacetates; Analgesia; Analgesics; Anesthesia, General; Anesthetics; beta-Endorphin; Blood Glucose; Cardiac Surgical Procedures; Diazepam; Epinephrine; Female; Fentanyl; Halothane; Humans; Infant, Newborn; Insulin; Lactates; Lactic Acid; Male; Morphine; Norepinephrine; Postoperative Care; Stress, Physiological; Sufentanil

1992
[Postoperative course and endocrine stress reaction of geriatric patients with para-articular hip fractures. Prospective randomized study comparing spinal anesthesia and halothane intubation narcosis].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1990, Volume: 25, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Anesthesia, Endotracheal; Anesthesia, Spinal; Blood Pressure; Bupivacaine; Epinephrine; Female; Femoral Neck Fractures; Glycerol; Halothane; Heart Rate; Hormones; Humans; Hydrocortisone; Lactates; Lactic Acid; Male; Mepivacaine; Middle Aged; Norepinephrine; Postoperative Complications; Prospective Studies; Stress, Physiological; Vasopressins

1990
Effects of two differing halothane concentrations on the metabolic and endocrine responses to surgery.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Abdomen; Anesthesia, Inhalation; Blood Glucose; Blood Pressure; Epinephrine; Female; Glycerol; Halothane; Heart Rate; Humans; Hydrocortisone; Hysterectomy; Lactates; Lactic Acid; Norepinephrine

1986
Effects of ketamine anaesthesia on the metabolic response to pelvic surgery.
    British journal of anaesthesia, 1984, Volume: 56, Issue:5

    Topics: Adult; Anesthesia, Intravenous; Blood Glucose; Fallopian Tubes; Fatty Acids, Nonesterified; Female; Halothane; Hematocrit; Hemodynamics; Humans; Hydrocortisone; Intraoperative Period; Ketamine; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid

1984
Myocardial metabolism and hemodynamic responses to halothane or morphine anesthesia for coronary artery surgery.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:12

    Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Coronary Circulation; Energy Metabolism; Female; Halothane; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Middle Aged; Morphine; Myocardium; Oxygen Consumption

1982

Other Studies

32 other study(ies) available for halothane and lactic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The effect of haloperidol, spiperone and dantrolene on the concentrations of creatine phosphate, ATP and lactate in brain and skeletal muscle of the rat during halothane anesthesia.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 73, Issue:3

    Topics: Adenosine Triphosphate; Anesthesia; Animals; Antipsychotic Agents; Brain Chemistry; Dantrolene; Female; Haloperidol; Halothane; Lactates; Lactic Acid; Muscles; Phosphocreatine; Rats; Rats, Inbred Strains; Spiperone

1991
Myocardial and systemic hemodynamics during isovolemic hemodilution alone and combined with nitroprusside-induced controlled hypotension.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:2

    Topics: Analysis of Variance; Anesthesia, Inhalation; Animals; Blood Circulation; Carbon Dioxide; Coronary Circulation; Dogs; Evaluation Studies as Topic; Female; Halothane; Hemodilution; Hemodynamics; Hypotension, Controlled; Lactates; Lactic Acid; Male; Myocardium; Nitroprusside; Oxygen; Oxygen Consumption; Regional Blood Flow; Time Factors

1991
Influence of tissue acidification and halothane anesthesia on hepatic electrical and biochemical properties during ischemia.
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:1

    Topics: Acid-Base Equilibrium; Alanine; Animals; Female; Glucose; Glycerol; Halothane; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Liver Function Tests; Liver Glycogen; Mannitol; Membrane Potentials; Organ Preservation; Potassium Chloride; Procaine; Swine

1991
The effect of etomidate pretreatment on cerebral high energy metabolites, lactate, and glucose during severe hypoxia in the rat.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Energy Metabolism; Etomidate; Glucose; Halothane; Hypoxia; Lactates; Lactic Acid; Male; Nitrous Oxide; Random Allocation; Rats; Rats, Inbred Strains; Thiopental

1989
Treatment of porcine malignant hyperthermia: lactate gradient from muscle to blood.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:6

    Topics: Animals; Bicarbonates; Carbon Dioxide; Dantrolene; Halothane; Lactates; Lactic Acid; Malignant Hyperthermia; Muscles; Oxygen Consumption; Potassium; Recurrence; Swine

1986
Energy deficits in hepatocytes isolated from phenobarbital-treated or fasted rats and briefly exposed to halothane and hypoxia in vitro.
    Anesthesiology, 1986, Volume: 65, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Energy Metabolism; Fasting; Halothane; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Phenobarbital; Rats; Rats, Inbred F344

1986
Myoadenylate deaminase deficiency: inherited and acquired forms.
    Biochemical medicine, 1985, Volume: 33, Issue:2

    Topics: Adenylate Kinase; Ammonia; AMP Deaminase; Biopsy; Caffeine; Creatine Kinase; Female; Genetic Carrier Screening; Halothane; Homozygote; Humans; Isoenzymes; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Cramp; Muscles; Nucleotide Deaminases; Physical Exertion

1985
Effects of high-dose fentanyl anaesthesia on the established metabolic and endocrine response to surgery.
    Anaesthesia, 1984, Volume: 39, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Glucose; Blood Pressure; Fallopian Tubes; Female; Fentanyl; Halothane; Heart Rate; Hematocrit; Humans; Hydrocortisone; Lactates; Lactic Acid

1984
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:6

    Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Lactates; Lactic Acid; Malignant Hyperthermia; Muscle Contraction; Phenotype; Preoperative Care; Swine; Swine, Miniature; Thiopental

1983
A canine model of acute coronary artery stenosis: effects of deliberate hypotension.
    Anesthesiology, 1983, Volume: 59, Issue:3

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Electrocardiography; Halothane; Hemodynamics; Hypotension, Controlled; Lactates; Lactic Acid; Myocardium; Oxygen; Oxygen Consumption; Trimethaphan

1983
Isoflurane modulates phorbol myristate acetate-, prostaglandin D2-, and prostaglandin E2-induced alterations in hepatic flow and metabolism in the perfused liver in fasted rats.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:2

    Topics: Animals; Dinoprostone; Enzyme Activation; Fasting; Halothane; In Vitro Techniques; Isoflurane; Lactates; Lactic Acid; Liver; Liver Circulation; Male; Oxygen Consumption; Perfusion; Prostaglandin D2; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1994
Protective effects of halothane but not isoflurane against global ischaemic injury in the isolated working rat heart.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:3

    Topics: Animals; Halothane; Heart; In Vitro Techniques; Isoflurane; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Rats; Rats, Inbred WKY

1995
Cardiorespiratory, endocrine and metabolic changes in ponies undergoing intravenous or inhalation anaesthesia.
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:4

    Topics: Acepromazine; Adrenocorticotropic Hormone; Analgesics; Analysis of Variance; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Dissociative; Animals; Arginine Vasopressin; Blood Gas Analysis; Blood Glucose; Blood Pressure; Body Temperature; Cardiac Output; Catecholamines; Dopamine Antagonists; Electrocardiography; Endorphins; Halothane; Heart Rate; Hematocrit; Horses; Hydrocortisone; Imidazoles; Ketamine; Lactic Acid

1996
Effects of volatile anesthetics on the calcium ionophore A23187-mediated alterations in hepatic flow and metabolism in the perfused liver in fasted rats.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:1 Pt 1

    Topics: Anesthetics, Inhalation; Animals; Calcimycin; Calcium; Dose-Response Relationship, Drug; Ethers; Halothane; In Vitro Techniques; Ionophores; Isoflurane; Lactic Acid; Liver; Liver Circulation; Male; Methyl Ethers; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sevoflurane

1997
Midazolam and ketamine induction before halothane anaesthesia in ponies: cardiorespiratory, endocrine and metabolic changes.
    Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenocorticotropic Hormone; Anesthesia, General; Animals; Arginine Vasopressin; Blood Gas Analysis; Blood Glucose; Dopamine; Epinephrine; Halothane; Heart Rate; Hemodynamics; Horses; Hydrocortisone; Ketamine; Lactic Acid; Male; Midazolam; Norepinephrine; Respiration

1997
Halothane and xanthine oxidase increase hepatocellular enzyme release and circulating lactate after ischemia-reperfusion in rabbits.
    Anesthesiology, 1997, Volume: 87, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Halothane; Ischemia; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Rabbits; Reperfusion; Xanthine Oxidase

1997
Prolonged exposure to halothane and associated changes in carbohydrate metabolism in rat muscles in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Glucose; Carbohydrate Metabolism; Glycogen; Halothane; Lactic Acid; Male; Muscle, Skeletal; Phosphorylases; Rats; Rats, Wistar

1998
Adrenocortical and metabolic responses to dobutamine infusion during halothane anaesthesia in ponies.
    Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:4

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Blood Glucose; Blood Pressure; Dobutamine; Halothane; Hematocrit; Horses; Hydrocortisone; Hypotension; Infusions, Intravenous; Lactic Acid; Male

1998
Increased synthesis of nitric oxide in rat brain cortex due to halogenated volatile anesthetics confirmed by EPR spectroscopy.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:4

    Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain Chemistry; Calibration; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Energy Metabolism; Enzyme Inhibitors; Halothane; Isoflurane; Lactic Acid; Male; Methyl Ethers; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyruvic Acid; Rats; Rats, Wistar; Sevoflurane; Spin Trapping; Stimulation, Chemical

2002
Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth.
    Anesthesiology, 2003, Volume: 99, Issue:1

    Topics: Anemia; Anesthetics; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Blood Pressure; Blood Volume; Cardiac Output; Dogs; Electrodes; Halothane; Heart Rate; Hemodilution; Hemoglobins; Ketamine; Lactic Acid; Neuromuscular Nondepolarizing Agents; Oxygen; Pancuronium; Splenectomy; Vascular Resistance

2003
EXCESS LACTATE PRODUCTION DURING HALOTHANE ANESTHESIA IN MAN.
    JAMA, 1964, Dec-28, Volume: 190

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesiology; Blood Chemical Analysis; Blood Gas Analysis; Halothane; Humans; Lactates; Lactic Acid; Male; Metabolism; Monitoring, Physiologic; Pharmacology; Pyruvates

1964
Preslaughter stress and muscle energy largely determine pork quality at two commercial processing plants.
    Journal of animal science, 2004, Volume: 82, Issue:5

    Topics: Animals; Catecholamines; Crosses, Genetic; Female; Food-Processing Industry; Glycolysis; Halothane; Hydrocortisone; Hydrogen-Ion Concentration; Lactic Acid; Male; Meat; Muscle, Skeletal; Quality Control; Random Allocation; Regression Analysis; Stress, Physiological; Swine

2004
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    Anesthesiology, 2006, Volume: 104, Issue:1

    Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Creatine Kinase; Cresols; Dose-Response Relationship, Drug; Electrolytes; Glucose; Halothane; Ketamine; Lactic Acid; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Propofol; Pyruvic Acid; Ryanodine Receptor Calcium Release Channel; Swine

2006
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Injections, Intramuscular; Lactic Acid; Malignant Hyperthermia; Microdialysis; Swine

2006
Pharmacologic modulation of skeletal muscle metabolism: a microdialysis study.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:4

    Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; In Vitro Techniques; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

2006
Lactate concentrations in incisions indicate ischemic-like conditions may contribute to postoperative pain.
    The journal of pain, 2007, Volume: 8, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Foot; Halothane; Hindlimb; Hydrogen-Ion Concentration; Ischemia; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley

2007
Lactate extraction and myocardial damage after countershock at different energy levels.
    Journal of cardiothoracic anesthesia, 1988, Volume: 2, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Cardiomyopathies; Differential Threshold; Disease Models, Animal; Dogs; Electric Countershock; Halothane; Lactic Acid; Myocardium; Technetium Tc 99m Pyrophosphate; Time Factors

1988
The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell disease.
    Anesthesiology, 2007, Volume: 107, Issue:2

    Topics: Albumins; Anemia, Sickle Cell; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Substitutes; Disease Models, Animal; Halothane; Heart Rate; Hemoglobins; Hydroxyethyl Starch Derivatives; Hypoxia; Kaplan-Meier Estimate; Lactic Acid; Mice; Mice, Transgenic; Oxygen; Survival Analysis; Time Factors; Treatment Outcome

2007
[In-vivo diagnosis of malignant hyperthermia susceptibility: a microdialysis study].
    Der Anaesthesist, 2008, Volume: 57, Issue:8

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; Dialysis Solutions; Female; Halothane; Hemodynamics; Humans; Injections, Intramuscular; Lactic Acid; Male; Malignant Hyperthermia; Microdialysis; Middle Aged; Muscle, Skeletal; Myoglobin; Psychometrics; Young Adult

2008
Microdialysis monitoring of porcine liver metabolism during warm ischemia with arterial and portal clamping.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2009, Volume: 15, Issue:3

    Topics: Anesthesia; Animals; Constriction; Female; Glucose; Halothane; Hepatic Artery; Lactic Acid; Liver; Liver Circulation; Microdialysis; Midazolam; Monitoring, Physiologic; Portal Vein; Pyruvic Acid; Swine

2009
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:4

    Topics: Animals; Biomarkers; Chemistry, Pharmaceutical; Dantrolene; Disease Models, Animal; Halothane; Hemodynamics; Injections, Intravenous; Lactic Acid; Malignant Hyperthermia; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Nanoparticles; Pharmaceutical Solutions; Potassium; Swine; Time Factors

2011