Compounds > halothane

halothane and disulfiram

halothane has been researched along with disulfiram in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's3 (25.00)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Büch, HP; Eckes, L1
Halsey, MJ1
Cascorbi, HF1
George, G; Gilsbach, E; Rudolph, J; Scholler, KL1
Jørgensen, G1
Hankins, D; Kharasch, ED; Mautz, D; Thummel, KE1
Kenna, JG1
Emery, ME; Kharasch, ED; Spracklin, DK; Thummel, KE1

Reviews

1 review(s) available for halothane and disulfiram

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Trials

2 trial(s) available for halothane and disulfiram

ArticleYear
[The metabolism of halothane under the influence of thiopental, methohexital, etomidate, enflurane and disulfiram under clinical conditions (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Anesthesia; Biotransformation; Disulfiram; Drug Interactions; Enflurane; Etomidate; Halothane; Humans; Methohexital; Middle Aged; Thiopental

1980
Identification of the enzyme responsible for oxidative halothane metabolism: implications for prevention of halothane hepatitis.
    Lancet (London, England), 1996, May-18, Volume: 347, Issue:9012

    Topics: Adult; Alanine Transaminase; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Halothane; Hepatic Encephalopathy; Humans; Male; Oxidoreductases, N-Demethylating; Preoperative Care; Trifluoroacetic Acid

1996

Other Studies

9 other study(ies) available for halothane and disulfiram

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Influence of disulfiram, diethyldithiocarbamate and carbon disulfide on the metabolic formation of trifluoroacetic acid from halothane in the rat.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:9

    Topics: Anesthesia, Inhalation; Animals; Carbon Disulfide; Disulfiram; Ditiocarb; Fluoroacetates; Halothane; Kidney; Liver; Male; Rats; Rats, Inbred Strains; Thiocarbamates; Trifluoroacetic Acid

1985
The metabolic breakdown of inhalation anaesthetics and their clinical implications.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Disulfiram; Dogs; Ethers; Halothane; Humans; Kidney; Liver; Methoxyflurane; Phenobarbital; Time Factors

1973
Biotransformation of fluroxene.
    International anesthesiology clinics, 1974,Summer, Volume: 12, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Carbon Dioxide; Carbon Tetrachloride; Cats; Disulfiram; Dogs; Ethanol; Ethers; Fluoroacetates; Glucuronates; Halothane; Humans; Liver; Mice; Mortality; Pyrazoles; Rabbits; Triazoles

1974
[Effects of drugs on the liver. A review illustrated with 3 clinical cases].
    Ugeskrift for laeger, 1994, Jan-10, Volume: 156, Issue:2

    Topics: Acetaminophen; Adult; Aged; Androgens; Chemical and Drug Induced Liver Injury; Denmark; Disulfiram; Drug-Related Side Effects and Adverse Reactions; Female; Halothane; Humans; Male; Methotrexate; Middle Aged; Sulfamethizole

1994
Patients must be a virtue.
    Human & experimental toxicology, 1996, Volume: 15, Issue:12

    Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Halothane; Humans; Liver; Oxidation-Reduction

1996
Concordance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Bromides; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1 Inhibitors; Disulfiram; Enzyme Induction; Enzyme Inhibitors; Halothane; Isoniazid; Liver; Male; Oxidation-Reduction; Proteins; Rats; Rats, Sprague-Dawley; Trifluoroacetic Acid

2003