halothane and dantrolene

halothane has been researched along with dantrolene in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (52.75)	18.7374
1990's	26 (28.57)	18.2507
2000's	8 (8.79)	29.6817
2010's	7 (7.69)	24.3611
2020's	2 (2.20)	2.80

Authors

Authors	Studies
Hall, GM; Lister, D; Lucke, JN	3
Flewellen, EH; Nelson, TE	3
Harrison, GG	2
Gronert, GA; Milde, JH; Theye, RA	2
Anderson, IL; Jones, EW	1
Holland, M; Lee, JC; Williams, JH	1
O'Donnell, D; Schwid, HA	1
Bonnet, M; Dufourc, EJ; Gaillard, S; Renou, JP	1
Dufourc, EJ; Gaillard, S; Renou, JP; Rock, E; Vignon, X	1
McLoughlin, JV; Wheatley, AM	1
Eldar, I; Glauber, V; Goldberg, G; Perel, A	1
Denborough, MA; Foster, PS; Hopkinson, KC; Payne, N	1
MacIver, MB; Mody, I; Tanelian, DL	1
Nelson, TE	2
Heffron, JJ; McSweeney, DM	1
Allen, PD; Lopez, I; Lopez, JR; Mendoza, M; Ryan, JF; Sanchez, V; Sreter, FA	1
Fang, SR; Flick, JL; Horiuchi, K; Ohnishi, ST; Ohnishi, T; Sadanaga, KK; Waring, AJ	1
Ohnishi, ST	1
Denborough, MA; Foster, PS; Hopkinson, KC	1
Ording, H	1
Gallant, EM; Iaizzo, PA; Lehmann-Horn, F; Taylor, SR	1
Denborough, MA; Foster, PS	1
Ahern, CP; Gronert, GA; Milde, JH	1
Suarez-Kurtz, G; Sudo, RT; Zapata, G	1
Alamo, L; Allen, PD; Jones, D; López, JR; Sreter, FA	1
Dhandha, SK	1
Fletcher, JE; Kistler, P; Michaux, K; Rosenberg, H	1
Fukumitsu, K; Hayashi, Y; Sumikawa, K; Yoshiya, I	1
Souza, MR; Suarez-Kurtz, G; Sudo, RT; Zapata, G	1
Håkanson, E; Rutberg, H	1
Fletcher, JE; Rosenberg, H	1
James, OF	1
Adnet, P; Krivosic-Horber, R; Theunynck, D	1
Bockman, EL; Deuster, PA; Muldoon, SM	1
Foldes, FF; Gallant, EM; Gronert, GA; Rempel, WE	1
Dan, K; Higa, K; Naitoh, H; Noda, B	1
Braun, J; Plötz, J	1
Alamo, LA; Allen, P; Gergely, J; Jones, D; López, JR; Papp, L; Streter, F	1
Herman, R; Reid, RE; Teng, CS	1
Bianchi, S; Camilli-Giammei, T; Di Lazzaro, M; Di Prospero, S	1
Asari, H; Hirose, Y; Inoue, K; Maruta, H	1
Bittar, EE; Helmer, P; Rusy, B	1
Hodgson, D; Kelly, AB; Manley, SV	1
Ellis, FR; Halsall, PJ	1
Gronert, GA; Ohnishi, ST; Taylor, S	1
Anderson, IL; Dunlop, DJ; Rawstron, RE	1
Gronert, GA; Onofrio, BM; Thompson, RL	1
Braun, J; Plötz, J; Stallenberger, R	1
Klein, LV; Leitch, M; Rosenberg, H; Waldron-Mease, E	1
Bee, DE; Flewellen, EH; Nelson, TE	1
Crocker, BD; Denborough, MA; Okumura, F	1
Fairhurst, AS; Hamamoto, V; Macri, J	1
Hadji, B; Löscher, W; Richter, A; Roewer, N; Scholz, J; Schulte am Esch, J; Steinfath, M; Tonner, PH; Wappler, F; Wlaz, P	1
Adnet, P; Adnet-Bonte, C; Bello, N; Etchrivi, T; Krivosic-Horber, R; Lestavel, P; Reyford, H; Saulnier, F; Tavernier, B	1
Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME	1
Gerdes, C; Löscher, W; Richter, A	1
Klont, RE; Lambooy, E; van Logtestijn, JG	1
Bichel, T; Canivet, JL; Damas, P; Lamy, M	1
Hoffman, WE; Kochs, E; Schulte am Esch, J	1
Blackwell, KE; Wackym, PA	1
Braune, H; Köchling, A; Reissinger, T; Roewer, N; Schulte am Esch, J; Wappler, F	1
Lamb, GD; Owen, VJ; Taske, NL	1
Collins, SP; Mendes, LS	1
Adnet, P; Ben Abraham, R; Glauber, V; Perel, A	1
Ashida, K; Azukari, K; Kasamatsu, Y; Ohsawa, A; Osada, M; Yoshioka, K	1
Allen, GC; Brubaker, CL	1
Cardinaud, JP; Favier, JC; Gbikpi-Benissan, G; Gruson, D; Hilbert, G; Portel, L	1
Barbosa, J; Gomez, MV; Gomez, RS; Guatimosim, C; Massensini, AR; Prado, MA	2
Fukami, MC; Ganzberg, SI	1
Anetseder, M; Müller, R; Roewer, N; Schuster, F; Tas, P	1
Copello, JA; Diaz-Sylvester, PL; Porta, M	1
Chen, SR; Chen, W; Fruen, B; Jiang, D; Jones, PP; Kong, H; Wang, R; Xiao, J; Zhang, L	1
Canato, M; Dainese, M; Dirksen, RT; Lyfenko, AD; Paolini, C; Protasi, F; Quarta, M; Reggiani, C	1
Urwyler, A	1
Becker, S; Burmester, S; Gerbershagen, MU; Kröner, L; Lenz, D; Schütte, JK; Starosse, A; Wappler, F	1
Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC	1
Hu, C; Kraeva, N; Larach, MG; Massey, C; Riazi, S; Wijeysundera, D	1
Kraeva, N; Larach, MG; Riazi, S; Rosenberg, H; Sterling, C; Timmins, MA	1
Alsina, E; Del Blanco, B; Domínguez, A; García, A; Guerrero, JL; Kollmann-Camaiora, A; Yepes, MJ	1
Choi, RH; Koenig, X; Launikonis, BS	1
Ibarra Moreno, CA; Jungbluth, H; Kraeva, N; Riazi, S; Voermans, NC; Zvaritch, E	1
Fu, PH; Ho, CN	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1

Reviews

9 review(s) available for halothane and dantrolene

Article	Year
Treatment of porcine malignant hyperthermia. A review based on experimental studies. Anaesthesia, 1975, Volume: 30, Issue:3 Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Catecholamines; Chlorpromazine; Dantrolene; Electrocardiography; Halothane; Humans; Hydrogen-Ion Concentration; Magnesium; Malignant Hyperthermia; Muscle Rigidity; Phentolamine; Potassium; Procainamide; Procaine; Succinylcholine; Swine; Triiodothyronine	1975
Anaesthesia of pigs sensitive to malignant hyperthermia. The Veterinary record, 1977, Jan-15, Volume: 100, Issue:3 Topics: Anesthesia; Animals; Barbiturates; Body Temperature; Cardiac Output; Dantrolene; Halothane; Heart Rate; Magnesium Sulfate; Malignant Hyperthermia; Muscles; Nitrous Oxide; Procaine; Stress, Physiological; Succinylcholine; Swine; Swine Diseases	1977
Pathophysiology of malignant hyperthermia. Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5 Topics: Animals; Calcium; Creatine Kinase; Dantrolene; Disease Susceptibility; Halothane; Humans; Lymphocytes; Malignant Hyperthermia; Mitochondria, Muscle; Muscles; Myoglobin; Stress, Physiological; Succinylcholine; Swine	1989
Studies of the halothane-cooling contractures of skeletal muscle. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:4 Topics: Anesthetics, Local; Animals; Calcium; Cold Temperature; Dantrolene; Halothane; Humans; Muscle Contraction; Salicylates; Sarcoplasmic Reticulum; Succinylcholine	1987
Drugs and the ageing liver. Journal of hepatology, 1985, Volume: 1, Issue:4 Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dantrolene; Drug-Related Side Effects and Adverse Reactions; Halothane; Humans; Kinetics; Liver; Liver Circulation; Liver Cirrhosis; Liver Diseases; Microsomes, Liver; Mixed Function Oxygenases; Orosomucoid; Oxidation-Reduction; Pharmaceutical Preparations; Propionates; Risk; Serum Albumin	1985
Current concepts. The malignant hyperthermia syndrome. The New England journal of medicine, 1983, Aug-18, Volume: 309, Issue:7 Topics: Animals; Dantrolene; Disease Models, Animal; Halothane; Humans; Malignant Hyperthermia; Muscles; Swine; Swine Diseases	1983
Malignant hyperthermia--pearls out of swine? British journal of anaesthesia, 1980, Volume: 52, Issue:2 Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Halothane; Magnesium Sulfate; Malignant Hyperthermia; Physical Exertion; Procainamide; Procaine; Succinylcholine; Swine; Sympathetic Nervous System; Syndrome	1980
Malignant hyperthermia. Postgraduate medical journal, 1998, Volume: 74, Issue:867 Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Muscle Relaxants, Central	1998
Clinical protocol for the management of malignant hyperthermia. Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:1 Topics: Adolescent; Adult; Caffeine; Calcium Signaling; Child; Child, Preschool; Clinical Protocols; Critical Care; Dantrolene; Diagnosis, Differential; Disease Management; Female; Halothane; Humans; Infant; Infant, Newborn; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Neuroleptic Malignant Syndrome; Ryanodine Receptor Calcium Release Channel; Serotonin Syndrome	2017

Trials

2 trial(s) available for halothane and dantrolene

Article	Year
[Serum myoglobin following intermittent administration of succinylcholine and the effect of dantrolene. Clinical studies of children in halothane anesthesia]. Der Anaesthesist, 1985, Volume: 34, Issue:10 Topics: Anesthesia; Child; Dantrolene; Halothane; Humans; Muscle Relaxation; Myoglobin; Preanesthetic Medication; Random Allocation; Succinylcholine; Time Factors	1985
[The inhibitory effect of dantrolene on the rise of serum-creatine-kinase activity after combined use of halothane and suxamethonium in man (author's transl)]. Der Anaesthesist, 1981, Volume: 30, Issue:7 Topics: Anesthesia; Child; Creatine Kinase; Dantrolene; Double-Blind Method; Female; Halothane; Humans; Male; Succinylcholine	1981

Other Studies

80 other study(ies) available for halothane and dantrolene

Article	Year
Rationale for dantrolene vs. procainamide for treatment of malignant hyperthermia. Anesthesiology, 1979, Volume: 50, Issue:2 Topics: Animals; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Halothane; Hydantoins; Malignant Hyperthermia; Muscle Contraction; Muscles; Procainamide; Swine	1979
Does prior dantrolene affect the in vitro diagnosis of malignant hyperthermia susceptibility? Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:6 Topics: Animals; Biopsy; Caffeine; Dantrolene; Drug Interactions; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine; Time Factors	1979
The prophylaxis of malignant hyperthermia by oral dantrolene sodium in swine. British journal of anaesthesia, 1977, Volume: 49, Issue:4 Topics: Administration, Oral; Anesthesia, General; Anesthesia, Inhalation; Animals; Dantrolene; Halothane; Hydantoins; Malignant Hyperthermia; Succinylcholine; Swine	1977
Role of sympathetic activity in porcine malignant hyperthermia. Anesthesiology, 1977, Volume: 47, Issue:5 Topics: Acidosis; Acidosis, Respiratory; Anesthesia, Conduction; Anesthesia, Spinal; Animals; Catecholamines; Dantrolene; Denervation; Depression, Chemical; Electrolytes; Halothane; Hemorrhage; Hypotension; Malignant Hyperthermia; Swine; Sympathetic Nervous System	1977
Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium. British journal of anaesthesia, 1975, Volume: 47, Issue:1 Topics: Anesthesia, General; Animals; Dantrolene; Halothane; Hydantoins; Malignant Hyperthermia; Mannitol; Sodium; Sodium Hydroxide; Swine	1975
Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle. Anesthesiology, 1976, Volume: 44, Issue:1 Topics: Animals; Caffeine; Calcium; Contracture; Dantrolene; Halothane; Hydantoins; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Sarcoplasmic Reticulum; Swine	1976
Dantrolene in porcine malignant hyperthermia. Anesthesiology, 1976, Volume: 44, Issue:6 Topics: Animals; Dantrolene; Halothane; Hydantoins; Malignant Hyperthermia; Succinylcholine; Swine	1976
W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:2 Topics: Animals; Caffeine; Calcium; Calmodulin; Dantrolene; Drug Synergism; Halothane; Intercellular Signaling Peptides and Proteins; Malignant Hyperthermia; Muscle Contraction; Peptides; Sulfonamides; Swine; Wasp Venoms	1992
Educational computer simulation of malignant hyperthermia. Journal of clinical monitoring, 1992, Volume: 8, Issue:3 Topics: Adult; Body Temperature; Computer Simulation; Dantrolene; Education, Medical; Female; Halothane; Humans; Malignant Hyperthermia; Models, Biological; Models, Cardiovascular; Muscles; Nitrous Oxide; Pharmacokinetics; Pharmacology; Respiration; Software Design; Succinylcholine; Teaching; Water-Electrolyte Balance	1992
Dantrolene inhibits halothane-induced membrane reorganization. A study using 31P-NMR and differential scanning calorimetry. European biophysics journal : EBJ, 1992, Volume: 21, Issue:1 Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Biophysics; Calorimetry, Differential Scanning; Dantrolene; Halothane; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membranes, Artificial	1992
31P NMR and freeze fracture studies of sarcoplasmic reticulum membranes from normal and malignant hyperthermic pigs: effect of halothane and dantrolene. Archives of biochemistry and biophysics, 1992, Volume: 294, Issue:1 Topics: Animals; Dantrolene; Freeze Fracturing; Halothane; Magnetic Resonance Spectroscopy; Malignant Hyperthermia; Microscopy, Electron; Muscles; Sarcoplasmic Reticulum; Swine	1992
The effect of haloperidol, spiperone and dantrolene on the concentrations of creatine phosphate, ATP and lactate in brain and skeletal muscle of the rat during halothane anesthesia. Research communications in chemical pathology and pharmacology, 1991, Volume: 73, Issue:3 Topics: Adenosine Triphosphate; Anesthesia; Animals; Antipsychotic Agents; Brain Chemistry; Dantrolene; Female; Haloperidol; Halothane; Lactates; Lactic Acid; Muscles; Phosphocreatine; Rats; Rats, Inbred Strains; Spiperone	1991
[In vitro diagnosis of malignant hyperpyrexia syndrome]. Harefuah, 1991, Dec-15, Volume: 121, Issue:12 Topics: Adult; Caffeine; Dantrolene; Female; Halothane; Hernia, Inguinal; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles	1991
The effect of azumolene on hypercontractility and sarcoplasmic reticulum Ca(2+)-dependent ATPase activity of malignant hyperpyrexia-susceptible porcine skeletal muscle. Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:7 Topics: Animals; Caffeine; Calcium-Transporting ATPases; Dantrolene; Halothane; Imidazoles; Malignant Hyperthermia; Muscle Contraction; Muscle Relaxants, Central; Muscles; Oxazoles; Potassium Chloride; Sarcoplasmic Reticulum	1991
Halothane enhances tonic neuronal inhibition by elevating intracellular calcium. Brain research, 1991, Jan-11, Volume: 538, Issue:2 Topics: Animals; Bicuculline; Calcium; Dantrolene; Egtazic Acid; Evoked Potentials; gamma-Aminobutyric Acid; Halothane; Hippocampus; In Vitro Techniques; Male; Neurons; Pentobarbital; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses	1991
Malignant hyperthermia in dogs. Journal of the American Veterinary Medical Association, 1991, Mar-15, Volume: 198, Issue:6 Topics: Animals; Biopsy; Caffeine; Crosses, Genetic; Dantrolene; Dog Diseases; Dogs; Female; Halothane; Heart Rate; Male; Malignant Hyperthermia; Muscle Contraction; Pedigree	1991
Uptake and release of calcium ions by heavy sarcoplasmic reticulum fraction of normal and malignant hyperthermia-susceptible human skeletal muscle. The International journal of biochemistry, 1990, Volume: 22, Issue:4 Topics: Azides; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Dantrolene; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles; Phenylmethylsulfonyl Fluoride; Sarcoplasmic Reticulum; Sodium Azide	1990
The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine. Anesthesiology, 1990, Volume: 73, Issue:1 Topics: Animals; Calcium; Dantrolene; Disease Susceptibility; Extracellular Space; Halothane; Magnesium Sulfate; Malignant Hyperthermia; Membrane Potentials; Microelectrodes; Muscles; Species Specificity; Swine	1990
Abnormal membrane properties of the sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia: modes of action of halothane, caffeine, dantrolene, and two other drugs. Archives of biochemistry and biophysics, 1986, Volume: 247, Issue:2 Topics: Animals; Caffeine; Calcium; Dantrolene; Electron Spin Resonance Spectroscopy; Halothane; Intracellular Membranes; Malignant Hyperthermia; Microsomes; Permeability; Ruthenium Red; Sarcoplasmic Reticulum; Swine; Tetracaine	1986
Effects of halothane, caffeine, dantrolene and tetracaine on the calcium permeability of skeletal sarcoplasmic reticulum of malignant hyperthermic pigs. Biochimica et biophysica acta, 1987, Feb-26, Volume: 897, Issue:2 Topics: Animals; Caffeine; Calcium; Cell Membrane Permeability; Dantrolene; Halothane; Kinetics; Malignant Hyperthermia; Ruthenium Red; Sarcoplasmic Reticulum; Swine; Tetracaine	1987
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle. Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:10 Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Verapamil	1989
Malignant hyperthermia: effects of halothane on the surface membrane. Muscle & nerve, 1989, Volume: 12, Issue:3 Topics: Action Potentials; Animals; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscles; Swine	1989
Effect of diltiazem and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible porcine skeletal muscle. British journal of anaesthesia, 1989, Volume: 62, Issue:5 Topics: Animals; Caffeine; Dantrolene; Diltiazem; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Swine	1989
Treatment of porcine malignant hyperthermia: lactate gradient from muscle to blood. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:6 Topics: Animals; Bicarbonates; Carbon Dioxide; Dantrolene; Halothane; Lactates; Lactic Acid; Malignant Hyperthermia; Muscles; Oxygen Consumption; Potassium; Recurrence; Swine	1986
Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine. Muscle & nerve, 1988, Volume: 11, Issue:1 Topics: Animals; Calcium; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscles; Osmolar Concentration; Swine	1988
Reversal of prolonged postoperative muscle rigidity by dantrolene: a case report. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:4 Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Dantrolene; Halothane; Humans; Male; Muscle Rigidity; Nitrous Oxide; Pancuronium; Postoperative Complications; Thiopental	1988
Dantrolene and mepacrine antagonize the hemolysis of human red blood cells by halothane and bee venom phospholipase A2. Toxicology and applied pharmacology, 1987, Sep-30, Volume: 90, Issue:3 Topics: Bee Venoms; Dantrolene; Dose-Response Relationship, Drug; Halothane; Hemolysis; Humans; Hydrolysis; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Quinacrine	1987
Selective inhibition by dantrolene of caffeine-induced catecholamine release from perfused dog adrenals. Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:1 Topics: Adrenal Glands; Animals; Caffeine; Catecholamines; Dantrolene; Dogs; Female; Halothane; In Vitro Techniques; Male; Perfusion	1987
Halothane-cooling contractures of mammalian muscles. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: Anesthetics, Local; Animals; Caffeine; Calcium; Cold Temperature; Dantrolene; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Mice; Muscle Contraction; Temperature	1986
Malignant hyperthermia: clinical course and metabolic changes in two patients. Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:3 Topics: Catecholamines; Child; Child, Preschool; Dantrolene; Female; Halothane; Humans; Hydrocortisone; Malignant Hyperthermia	1986
In vitro muscle contractures induced by halothane and suxamethonium. I: The rat diaphragm. British journal of anaesthesia, 1986, Volume: 58, Issue:12 Topics: Animals; Dantrolene; Diaphragm; Drug Synergism; Halothane; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Quinacrine; Rats; Rats, Inbred Strains; Spermine; Succinylcholine; Tubocurarine	1986
[Capnography and anesthetic-induced malignant hyperthermia]. Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1985, Volume: 26, Issue:11 Topics: Animals; Carbon Dioxide; Dantrolene; Halothane; Malignant Hyperthermia; Monitoring, Physiologic; Succinylcholine; Swine	1985
In vitro responses of cat skeletal muscle to halothane and caffeine. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2 Topics: Animals; Caffeine; Cats; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Halothane; Hypertension, Malignant; Muscle Contraction; Muscles	1985
Verapamil is not a therapeutic adjunct to dantrolene in porcine malignant hyperthermia. Anesthesia and analgesia, 1985, Volume: 64, Issue:6 Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dantrolene; Drug Synergism; Halothane; Heart Rate; Infusions, Parenteral; Malignant Hyperthermia; Muscle Contraction; Succinylcholine; Swine; Verapamil	1985
[A case of malignant hyperthermia; successful treatment with intravenous dantrolene sodium]. Masui. The Japanese journal of anesthesiology, 1985, Volume: 34, Issue:6 Topics: Anesthesia, Inhalation; Child, Preschool; Dantrolene; Female; Halothane; Humans; Injections, Intravenous; Intraoperative Complications; Malignant Hyperthermia; Strabismus	1985
[Determination of intracellular free calcium concentration, in vivo, in swine susceptible to malignant hyperthermia syndrome]. Acta cientifica venezolana, 1985, Volume: 36, Issue:1 Topics: Animals; Calcium; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscles; Succinylcholine; Swine	1985
Attempts at altering ureteral activity in the unanesthetized, conditioned dog with commonly employed drugs. Investigative urology, 1974, Volume: 12, Issue:1 Topics: Adrenergic beta-Agonists; Albuterol; Analgesics; Animals; Atropine; Conditioning, Classical; Dantrolene; Diazepam; Dogs; Female; Halothane; Methacholine Compounds; Methods; Muscles; Nerve Endings; Nitrous Oxide; Pentobarbital; Pentolinium Tartrate; Phenoxybenzamine; Propantheline; Propranolol; Terbutaline; Tetracaine; Ureter	1974
[Malignant hyperthermia: biochemico-metabolic aspects and personal experiences]. La Clinica terapeutica, 1984, Sep-30, Volume: 110, Issue:6 Topics: Adult; Dantrolene; Female; Halothane; Humans; Male; Malignant Hyperthermia; Succinylcholine	1984
Dantrolene does not block calcium pulse-induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle. FEBS letters, 1984, Feb-13, Volume: 167, Issue:1 Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; Ion Channels; Malignant Hyperthermia; Muscle Contraction; Sarcoplasmic Reticulum; Swine	1984
The inhibitory effect of intravenous d-tubocurarine and oral dantrolene on halothane-succinylcholine-induced myoglobinemia in children. Anesthesiology, 1984, Volume: 61, Issue:3 Topics: Administration, Oral; Anesthesia; Child; Child, Preschool; Dantrolene; Female; Halothane; Humans; Injections, Intravenous; Male; Myoglobin; Succinylcholine; Tubocurarine	1984
Sensitivity to halothane of the sodium efflux in single barnacle muscle fibers. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2 Topics: Animals; Calcium; Dantrolene; Egtazic Acid; Halothane; Membrane Potentials; Muscles; Ouabain; Procaine; Sodium; Thoracica; Verapamil	1981
Malignant hyperthermia-like reactions in three anesthetized horses. Journal of the American Veterinary Medical Association, 1983, Jul-01, Volume: 183, Issue:1 Topics: Anesthesia, General; Animals; Dantrolene; Female; Halothane; Horse Diseases; Horses; Male; Malignant Hyperthermia; Swine; Swine Diseases; Syndrome	1983
The control of muscle contracture by the action of dantrolene on the sarcolemma. Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:3 Topics: Animals; Caffeine; Dantrolene; Diaphragm; Dinitrophenols; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Rats; Sarcolemma	1983
Calcium-induced Ca2+ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. The effects of halothane and dantrolene. FEBS letters, 1983, Sep-05, Volume: 161, Issue:1 Topics: Animals; Calcium; Dantrolene; Halothane; Kinetics; Malignant Hyperthermia; Sarcoplasmic Reticulum; Swine	1983
Screening for malignant hyperthermia susceptibility. The New Zealand medical journal, 1980, Jun-11, Volume: 91, Issue:661 Topics: Caffeine; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Mass Screening; Muscle Contraction; Muscles	1980
Human malignant hyperthermia: awake episodes and correction by dantrolene. Anesthesia and analgesia, 1980, Volume: 59, Issue:5 Topics: Adenosine Triphosphate; Adult; Caffeine; Dantrolene; Fatigue; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Stress, Physiological; Wakefulness	1980
Malignant hyperthermia in a halothane-anesthetized horse. Journal of the American Veterinary Medical Association, 1981, Nov-01, Volume: 179, Issue:9 Topics: Anesthesia, Inhalation; Animals; Dantrolene; Fluid Therapy; Halothane; Horse Diseases; Horses; Male; Malignant Hyperthermia; Oxygen Inhalation Therapy	1981
Porcine malignant hyperthermia--failure of dantrolene dose response to diagnose susceptibility (halothane effect). Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:1 Topics: Animals; Dantrolene; Dose-Response Relationship, Drug; Drug Synergism; Female; Halothane; Male; Malignant Hyperthermia; Swine; Thiopental	1980
Site of the muscle cell abnormality in swine susceptible to malignant hyperpyrexia. British journal of anaesthesia, 1980, Volume: 52, Issue:4 Topics: Acetylcholine; Animals; Caffeine; Dantrolene; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Potassium Chloride; Swine; Thymol; Tubocurarine	1980
Modification of ryanodine toxicity by dantrolene and halothane in a model of malignant hyperthermia. Anesthesiology, 1980, Volume: 53, Issue:3 Topics: Alkaloids; Animals; Dantrolene; Diaphragm; Disease Models, Animal; Halothane; In Vitro Techniques; Male; Malignant Hyperthermia; Mice; Rats; Ryanodine; Succinylcholine	1980
Alterations of inositol polyphosphates in skeletal muscle during porcine malignant hyperthermia. British journal of anaesthesia, 1995, Volume: 75, Issue:4 Topics: Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Dantrolene; Disease Susceptibility; Halothane; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Malignant Hyperthermia; Muscle, Skeletal; Swine	1995
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome]. Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:5 Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Neuroleptic Malignant Syndrome	1994
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Dantrolene; Disease Susceptibility; Halothane; Humans; Incidence; Infant; Intraoperative Complications; Malignant Hyperthermia; Middle Aged; Muscle, Skeletal; Nerve Block; Retrospective Studies	1995
Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:4 Topics: Animals; Blood Pressure; Body Temperature; Dantrolene; Female; Halothane; Heart Rate; Ketanserin; Male; Malignant Hyperthermia; Premedication; Ritanserin; Species Specificity; Swine	1994
Effect of dantrolene treatment on muscle metabolism and meat quality of anesthetized pigs of different halothane genotypes. Journal of animal science, 1994, Volume: 72, Issue:8 Topics: Anesthesia; Animals; Biopsy, Needle; Calcium; Creatine; Dantrolene; Genotype; Glycogen; Halothane; Hydrogen-Ion Concentration; Lactates; Male; Malignant Hyperthermia; Meat; Muscle, Skeletal; Phosphocreatine; Stress, Physiological; Swine; Swine Diseases	1994
Malignant hyperthermia and severe hypoglycemia after reexposure to halothane. Acta anaesthesiologica Belgica, 1994, Volume: 45, Issue:1 Topics: Child, Preschool; Dantrolene; Female; Halothane; Humans; Hypoglycemia; Liver; Malignant Hyperthermia; Nasolacrimal Duct	1994
Improvement of brain electrical activity during treatment of porcine malignant hyperthermia with dantrolene. British journal of anaesthesia, 1993, Volume: 71, Issue:6 Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Dantrolene; Electroencephalography; Halothane; Malignant Hyperthermia; Oxygen; Partial Pressure; Swine	1993
Malignant hyperthermia in the otology patient: the UCLA experience. The American journal of otology, 1994, Volume: 15, Issue:3 Topics: Administration, Inhalation; Adult; Anesthetics; Caffeine; Child; Child, Preschool; Dantrolene; Female; Halothane; Humans; Infant; Male; Malignant Hyperthermia; Middle Ear Ventilation; Muscle Relaxants, Central; Otolaryngology; Otorhinolaryngologic Diseases; Oxygen Consumption	1994
Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma. Intensive care medicine, 1996, Volume: 22, Issue:8 Topics: Adult; Caffeine; Cresols; Dantrolene; Diabetic Coma; Diabetic Ketoacidosis; Fever; Halothane; Humans; Male; Muscle Relaxants, Central	1996
Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia. The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1 Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Genetic Predisposition to Disease; Genotype; Halothane; Magnesium; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Osmolar Concentration; Swine	1997
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro. Pharmacological research, 1997, Volume: 36, Issue:6 Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Trifluoperazine	1997
Rhabdomyolysis after infection and taking a cold medicine in a patient who was susceptible to malignant hyperthermia. Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:2 Topics: Adult; Caffeine; Chlorpheniramine; Common Cold; Dantrolene; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Nonprescription Drugs; Phenylephrine; Phenylpropanolamine; Rhabdomyolysis; Virus Diseases	1998
Human malignant hyperthermia associated with desflurane anesthesia. Anesthesia and analgesia, 1998, Volume: 86, Issue:6 Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Child; Child, Preschool; Dantrolene; Databases as Topic; Desflurane; Drug Interactions; Female; Halothane; Humans; Isoflurane; Male; Malignant Hyperthermia; Middle Aged; Muscle Relaxants, Central; Neuromuscular Depolarizing Agents; Succinylcholine; Time Factors	1998
Malignant hyperthermia and neuroleptic malignant syndrome in a patient during treatment for acute asthma. Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1 Topics: Acute Disease; Adjuvants, Anesthesia; Adult; Anesthetics, Inhalation; Asthma; Bronchodilator Agents; Calcium Channel Blockers; Dantrolene; Droperidol; Glucocorticoids; Halothane; Humans; Intubation, Intratracheal; Magnesium Sulfate; Male; Malignant Hyperthermia; Methylprednisolone; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome; Neuromuscular Blocking Agents; Respiration, Artificial; Rhabdomyolysis	1999
Halothane-induced intracellular calcium release in cholinergic cells. Brain research, 2001, Dec-07, Volume: 921, Issue:1-2 Topics: Acetylcholine; Anesthetics, Inhalation; Aniline Compounds; Animals; Brain; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Dantrolene; Enzyme Inhibitors; Extracellular Space; Fluorescent Dyes; Halothane; Humans; Intracellular Fluid; Microscopy, Confocal; Muscle Relaxants, Central; Neurons; Potassium Chloride; Ryanodine; Ryanodine Receptor Calcium Release Channel; Synaptic Transmission; Xanthenes	2001
Translocation of protein kinase C by halothane in cholinergic cells. Brain research bulletin, 2002, Volume: 58, Issue:1 Topics: Anesthetics, Inhalation; Animals; Calcium; Cell Line; Cholinergic Fibers; Dantrolene; Green Fluorescent Proteins; Halothane; Indicators and Reagents; Isoenzymes; Luminescent Proteins; Microscopy, Confocal; Muscle Relaxants, Central; Protein Kinase C; Protein Kinase C beta	2002
A case report of malignant hyperthermia in a dental clinic operating room. Anesthesia progress, 2005,Spring, Volume: 52, Issue:1 Topics: Anesthetics, Inhalation; Child, Preschool; Dantrolene; Follow-Up Studies; Halothane; Humans; Jaw Fixation Techniques; Male; Malignant Hyperthermia; Mandibular Condyle; Mandibular Fractures; Muscle Relaxants, Central	2005
Pharmacologic modulation of skeletal muscle metabolism: a microdialysis study. Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:4 Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; In Vitro Techniques; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Rats; Rats, Sprague-Dawley	2006
Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca2+, Mg2+, and ATP. American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:4 Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Calcium; Cytosol; Dantrolene; Dogs; Halothane; Intracellular Membranes; Magnesium; Muscle Fibers, Skeletal; Muscle Relaxants, Central; Muscle, Skeletal; Myocytes, Cardiac; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum	2008
Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia. The Journal of biological chemistry, 2008, Jul-25, Volume: 283, Issue:30 Topics: Anesthetics, Inhalation; Animals; Calcium; Cell Line; Cytosol; Dantrolene; Fever; Halothane; Humans; Malignant Hyperthermia; Muscle Relaxants, Central; Mutagenesis, Site-Directed; Mutation; Sarcoplasmic Reticulum; Swine	2008
Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:6 Topics: Anesthetics; Animals; Caffeine; Calcium; Calcium-Binding Proteins; Calsequestrin; Central Nervous System Stimulants; Dantrolene; Death, Sudden; Female; Halothane; Hot Temperature; Humans; Male; Malignant Hyperthermia; Mice; Mice, Knockout; Muscle Relaxants, Central; Muscle, Skeletal; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Survival Rate	2009
Malignant hyperthermia: presymptomatic screening and treatment 2011. European journal of anaesthesiology, 2011, Volume: 28, Issue:4 Topics: Anesthetics, Inhalation; Animals; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal	2011
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs. European journal of anaesthesiology, 2011, Volume: 28, Issue:4 Topics: Animals; Biomarkers; Chemistry, Pharmaceutical; Dantrolene; Disease Models, Animal; Halothane; Hemodynamics; Injections, Intravenous; Lactic Acid; Malignant Hyperthermia; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Nanoparticles; Pharmaceutical Solutions; Potassium; Swine; Time Factors	2011
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene. Anaesthesia, 2012, Volume: 67, Issue:9 Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatine Kinase; Dantrolene; Disseminated Intravascular Coagulation; Female; Genetic Variation; Hallucinogens; Haloperidol; Halothane; Humans; Multiple Organ Failure; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Recurrence; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Spectrum Analysis; Young Adult	2012
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands. Anesthesia and analgesia, 2014, Volume: 118, Issue:2 Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female; Fever; Halothane; Humans; Hypercapnia; Incidence; Infant; Male; Malignant Hyperthermia; Middle Aged; Mutation; Registries; Retrospective Studies; Ryanodine Receptor Calcium Release Channel; Succinylcholine; Tachycardia; Young Adult	2014
Malignant hyperthermia testing in probands without adverse anesthetic reaction. Anesthesiology, 2015, Volume: 123, Issue:3 Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects and Adverse Reactions; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Retrospective Studies; Young Adult	2015
Dantrolene requires Mg Proceedings of the National Academy of Sciences of the United States of America, 2017, 05-02, Volume: 114, Issue:18 Topics: Adult; Animals; Calcium Signaling; Dantrolene; Female; Halothane; Humans; Magnesium; Male; Malignant Hyperthermia; Muscle, Skeletal; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel	2017
Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability. Anesthesia and analgesia, 2023, 03-01, Volume: 136, Issue:3 Topics: Dantrolene; Drug-Related Side Effects and Adverse Reactions; Fatigue; Halothane; Humans; Malignant Hyperthermia; Myalgia; Retrospective Studies; Rhabdomyolysis	2023
A Case Report of an Incidental Ultrasound Finding in a Suspected Malignant Hyperthermia Patient. A&A practice, 2022, Dec-01, Volume: 16, Issue:12 Topics: Anesthetics, Inhalation; Dantrolene; Female; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Succinylcholine	2022
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004