halothane has been researched along with cysteine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Black, M | 1 |
| Cohen, EN; Edmunds, HN; Trudell, JR; Watson, E | 1 |
| Anders, MW; Baggs, RB; Finkelstein, MB | 1 |
| Britt, BA; de Leon, S; Derdemezi, J; Duff, CL; Fujii, J; Gillard, EF; Khanna, VK; MacLennan, DH; Otsu, K; Worton, RG | 1 |
| Hayden, PJ; Ichimura, T; McCann, DJ; Pohl, LR; Stevens, JL | 1 |
| Chau, DD; Cheung, HT; Earl, J; Overton, J; Wark, H | 1 |
| Norström, A | 1 |
| Airaksinen, MM; Rosenberg, PH; Tammisto, T | 1 |
| Hori, M; Kamada, T; Kimura, Y; Kuzuya, T; Nishida, K; Otsu, K; Tada, M | 1 |
| Dutton, PL; Gibney, BR; Johansson, JS; Rabanal, F; Reddy, KS | 1 |
| Beaune, P; de Waziers, I; Eliasson, E; Gardner, I; Hume-Smith, H; Kenna, JG | 1 |
| Baeder, S; Baur, C; Calzia, E; Eichinger, HM; Froeba, G; Georgieff, M; Marx, T; Pazhur, J; Radermacher, P | 1 |
| Davies, LA; Klein, ML; Scharf, D; Zhong, Q | 1 |
| Johansson, JS; Raines, DE; Solt, K | 1 |
| Cook, AC; Ho, C; Malinowski, SA; Miller, KW; Shanmugasundararaj, S; Slater, SJ | 1 |
| Hogan, KJ; Vladutiu, GD | 1 |
1 review(s) available for halothane and cysteine
| Article | Year |
|---|---|
Hepatotoxicity: pathogenesis and therapeutic intervention.
Topics: Acetaminophen; Anabolic Agents; Androgens; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Erythromycin; Estrogens; Halothane; Humans; Isoniazid; Liver; Nitrofurantoin; Rifampin | 1979 |
15 other study(ies) available for halothane and cysteine
| Article | Year |
|---|---|
Urinary metabolites of halothane in man.
Topics: Binding Sites; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cysteine; Ethanolamines; Fluoroacetates; Glutathione; Halothane; Heart Transplantation; Humans; Liver; Tissue Donors; Transplantation, Homologous; Trifluoroacetic Acid | 1975 |
Nephrotoxicity of the glutathione and cysteine conjugates of 2-bromo-2-chloro-1,1-difluoroethene.
Topics: Animals; Blood Glucose; Body Weight; Cysteine; Glutathione; Halothane; Injections, Intraperitoneal; Kidney; Liver; Male; Organ Size; Rats; Rats, Inbred F344 | 1992 |
A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia.
Topics: Adolescent; Amino Acid Sequence; Arginine; Base Sequence; Caffeine; Cloning, Molecular; Cysteine; Exons; Female; Halothane; Humans; Male; Malignant Hyperthermia; Molecular Sequence Data; Muscle Proteins; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, Cholinergic; Restriction Mapping; Ryanodine Receptor Calcium Release Channel; White People | 1991 |
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.
Topics: Acetamides; Animals; Cross Reactions; Cysteine; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; Halothane; Hydrocarbons, Fluorinated; Immunoblotting; Immunohistochemistry; Kidney Diseases; Kidney Tubules, Proximal; Kinetics; Male; Mitochondria; Rats; Rats, Inbred Strains; Trifluoroacetic Acid | 1991 |
A urinary cysteine-halothane metabolite: validation and measurement in children.
Topics: Acetylcysteine; Anesthesia, Inhalation; Biotransformation; Child; Chromatography, High Pressure Liquid; Cysteine; Halothane; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Trifluoroacetic Acid | 1990 |
Biosynthesis of neurohypophysial proteins in rats with hereditary hypothalamic diabetes insipidus (Brattleboro strain).
Topics: Anesthesia, Inhalation; Animals; Culture Media; Culture Techniques; Cysteine; Diabetes Insipidus; Electrophoresis, Polyacrylamide Gel; Halothane; Hypothalamus; Injections; Male; Neurophysins; Pituitary Gland, Posterior; Rats; Sodium Dodecyl Sulfate | 1974 |
A possible mechanism of toxicity of trifluoroethanol and other halothane metabolites.
Topics: Alcohols; Aldehydes; Allopurinol; Animals; Cysteine; Drug Synergism; Ethanol; Fluorine; Halothane; Mice | 1970 |
The point mutation Arg615-->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Western; Caffeine; Calcium; Calcium Channels; Cell Line; Cysteine; Drug Hypersensitivity; Gene Library; Halothane; Intracellular Membranes; Malignant Hyperthermia; Mice; Microsomes; Muscle Proteins; Muscles; Point Mutation; Poly A; Rabbits; RNA; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Transfection | 1994 |
A designed cavity in the hydrophobic core of a four-alpha-helix bundle improves volatile anesthetic binding affinity.
Topics: Amino Acid Sequence; Anesthetics, Inhalation; Binding Sites; Cysteine; Drug Design; Electron Spin Resonance Spectroscopy; Halothane; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Solubility; Spectroscopy, Fourier Transform Infrared; Tryptophan; Water | 1998 |
Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroacetates; Cysteine; Cytochrome P-450 Enzyme System; Enzyme Activation; Glutathione; Halothane; Hepatitis Antigens; Inactivation, Metabolic; Individuality; Isoenzymes; Male; Microsomes, Liver; Peptides; Rabbits; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Trichloroacetic Acid | 1998 |
Xenon does not trigger malignant hyperthermia in susceptible swine.
Topics: Amino Acid Substitution; Anesthesia, General; Anesthetics, Inhalation; Animals; Arginine; Blood Pressure; Cardiac Output; Cysteine; Genetic Predisposition to Disease; Halothane; Heart Rate; Homozygote; Malignant Hyperthermia; Mutation; Ryanodine Receptor Calcium Release Channel; Swine; Xenon | 1999 |
Molecular dynamics simulation of four-alpha-helix bundles that bind the anesthetic halothane.
Topics: Amino Acid Sequence; Anesthetics, Inhalation; Binding Sites; Computer Simulation; Cysteine; Dimerization; Halothane; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Structure, Secondary; Thermodynamics | 2000 |
Kinetics of anesthetic-induced conformational transitions in a four-alpha-helix bundle protein.
Topics: Anesthetics, Inhalation; Cysteine; Halothane; Ion Channel Gating; Ion Channels; Kinetics; Ligands; Methyl Ethers; Models, Chemical; Protein Conformation; Protein Structure, Secondary; Proteins; Sensitivity and Specificity; Sevoflurane; Spectrometry, Fluorescence | 2006 |
Interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.
Topics: Allosteric Regulation; Anesthetics, Inhalation; Animals; Binding Sites; Cell Line; Cysteine; Diterpenes; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Halothane; Humans; Hydrophobic and Hydrophilic Interactions; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Spodoptera | 2008 |
Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Arginine; Carnitine O-Palmitoyltransferase; Child, Preschool; Cysteine; Female; Genetic Predisposition to Disease; Halothane; Heterozygote; Humans; Malignant Hyperthermia; Metabolism, Inborn Errors; Mutation; Neuromuscular Depolarizing Agents; Risk Factors; Succinylcholine; Syndrome | 2009 |