halothane and caffeine

halothane has been researched along with caffeine in 360 studies

Research

Studies (360)

TimeframeStudies, this research(%)All Research%
pre-1990130 (36.11)18.7374
1990's141 (39.17)18.2507
2000's56 (15.56)29.6817
2010's27 (7.50)24.3611
2020's6 (1.67)2.80

Authors

AuthorsStudies
Blake, JF; Curatolo, WJ; Lombardo, F1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Durbin, CG; Rosenberg, H1
Lampo, P; Muylle, E; Oyaert, W; van Cauteren, H; van den Hende, C1
Kalow, W1
Britt, BA; Chan, FY; Kalow, W1
Britt, BA2
Rosenberg, H3
Crocker, BD; Denborough, MA; Okumura, F2
Britt, BA; Harrison, JE; McNeill, KG1
Flewellen, EH; Nelson, TE5
Kerrick, WG; Su, JY1
Moulds, RF1
Austin, KL; Denborough, MA; Nelson, TE1
Britt, BA; Endrenyi, L; Kalow, W; Peters, PL1
Bedell, DM; Jones, EW; Nelson, TE1
Clarke, IM; Ellis, FR1
Anderson, IL; Jones, EW1
Hofmann, WW1
Holland, M; Lee, JC; Williams, JH3
Rooke, GA; Su, JY1
Bendixen, D; Ording, H2
Cosgrove, SB; Eisele, PH; Gronert, GA; Martucci, RW1
Ellis, FR; Halsall, PJ; Hopkins, PM3
Denborough, MA; Foster, PS; Hopkinson, KC2
Couchman, KG; McKenzie, AJ; Pollock, N1
Endo, M; Iino, M; Kawana, Y; Oyamada, H1
Carrier, L; Dupont, Y; Villaz, M1
Beech, J; Fletcher, JE; Rosenberg, H1
Adamantidis, MM; Adnet, PJ; Cordonnier, C; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, GH1
Holland, M; Lee, JC; McGrath, CJ; Ward, CW; Williams, JH1
Davy, KP; Holland, M; Lee, JC; Ward, CW; Williams, JH1
Bunn, JS; Diaz, M; Landis, JR; Larach, MG1
Adamantidis, MM; Adnet, PJ; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Reyford, HG1
Bossaert, LL; Heytens, L; Martin, JJ; Van de Kelft, E1
Knight, PR; Sheth, N; Wilde, DW; Williams, BA1
Kosay, S; Oyman, S; Tok, D; Ulker, S1
Gutta, R; Haney, MF; Knight, PR; Wilde, DW1
Katsuoka, M; Ohnishi, ST2
Britt, BA; de Leon, S; Derdemezi, J; Duff, CL; Fujii, J; Gillard, EF; Khanna, VK; MacLennan, DH; Otsu, K; Worton, RG1
Meinecke, CD; Olthoff, D1
Engelhardt, W; Hartung, E; Krauspe, R; Preis, I1
Eldar, I; Glauber, V; Goldberg, G; Perel, A1
Benders, AA; Joosten, EM; Poels, PJ; Sengers, RC; Stadhouders, AM; Veerkamp, JH1
Denborough, MA; Foster, PS; Hopkinson, KC; Payne, N1
Gallagher, WJ; Iaizzo, PA; Wedel, DJ1
Britt, B; Kalow, W; Sharer, S1
Roewer, N; Rum, U; Schmitz, W; Scholz, H; Scholz, J; Schulte am Esch, J1
Eichinger, HM; Iaizzo, PA; Lehmann-Horn, F; Seewald, MJ1
Cardinet, GH; Elliott, TE; Gronert, GA; Jaffe, RS; Martucci, RW1
Bonsett, C; Dierdorf, SF; Krishna, G; Patel, VK1
Britt, BA; Duff, C; Frodis, W; Fujii, J; Korneluk, RG; MacLennan, DH; Phillips, M; Worton, RG; Zorzato, F1
Allen, G; Chance, B; Olgin, J; Rosenberg, H; Seestedt, R1
Bonk, KR; Brooks, RR; Carpenter, JF; Miller, KE1
Nelson, TE3
Censier, K; Drewe, J; Frei, F; Rothenbühler, JM; Seeberger, MD; Urwyler, A1
Peracchia, C2
Fletcher, JE; Levitt, RC; Meyers, D; Rosenberg, H1
Allen, G; Crossan, ML; Korneluk, R; Lahey, D; MacKenzie, AE; MacLennan, DH; Mettler, G; Nolan, K; Worton, RG1
Britt, BA; Elliott, ME; Klip, A; Mills, GB1
Adamantidis, M; Adnet, P; Dupuis, B; Krivosic-Horber, R; Leys, D; Reyford, H1
O'Brien, PJ1
Mortier, W1
Fletcher, JE; Huggins, FJ; Rosenberg, H1
Stratton, M1
Suarez-Kurtz, G; Sudo, RT; Zapata-Sudo, G1
Iaizzo, PA; Lehmann-Horn, F2
Allen, GC; Conner, GE; Fletcher, JE; Huggins, FJ; Rosenberg, H1
Allen, GC; Conti, PA; Fletcher, JE; Huggins, FJ; Rosenberg, H1
Deufel, T; Farrall, M; Healy, JM; Heffron, JJ; Johnson, K; Lehane, M; Lehmann-Horn, F; McCarthy, TV1
Adamantidis, MM; Adnet, PJ; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Reyfort, GH1
Allen, GC; Fletcher, JE; Rosenberg, H1
Dubrow, TJ; Dudley, JP; Reynolds, R1
Arpin, D; Cardinet, G; Hildebrand, SV1
Gericke, GS; Isaacs, H1
Ording, H3
Ali, N; Kalow, BI; Lassaline, LA; Lumsden, JH; O'Brien, PJ1
Suarez-Kurtz, G; Sudo, RT; Trachez, MM1
Fang, SR; Flick, JL; Horiuchi, K; Ohnishi, ST; Ohnishi, T; Sadanaga, KK; Waring, AJ1
Ohnishi, ST1
Palade, P1
Krivosic, I; Krivosic-Horber, R1
Fletcher, JE; Gong, QH; Rosenberg, H; Wieland, SJ1
Adnet, P; Krivosic-Horber, R1
Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F1
Hackl, W; Mauritz, W; Steinbereithner, K; Winkler, M1
Larach, MG1
Iaizzo, PA; Lehmann-Horn, F; Oakes, SG; Seewald, M1
Kumeta, H; Namiki, A; Narimatsu, E; Sumita, S; Tateishi, M; Watanabe, H1
Denborough, MA; Foster, PS; Hopkinson, K1
Fletcher, JE; Lizzo, FH; Rosenberg, H1
Katsuoka, M; Kobayashi, K; Ohnishi, ST1
Denborough, MA; Foster, PS2
Krane, EJ; Su, JY1
Su, JY; Zhang, CC1
Gronert, GA; Kien, ND; Martucci, RW; Melton, AT1
Burket, RC; Hodgin, JD1
Gallant, EM; Jacobson, BA; Johnson, KM; Litterer, LA; Louis, CF; Mickelson, JR; Rempel, WE1
Britt, BA; Elliott, ME; Frodis, W; Klip, A; Pegg, W; Scott, E1
Endo, M; Morohoshi, Y; Nakano, T; Ohga, A; Ohta, T; Wanikawa, K1
Gage, PW; Robertson, B1
Gascard, JP; Kozak-Reiss, G; Laxenaire, MC; Moeller, R1
Abdul-Rasool, IH; Dubrow, TJ; Lesavoy, MA; Wackym, PA1
Hansford, RG; Lakatta, EG; Rice, RT; Wheeler, DM1
Pagala, MK; Sahgal, V; Shah, AJ; Subramani, V; Venkatachari, SA1
Collins, SP; Denborough, MA; White, MD1
Hansen, U; Ording, H; Skovgaard, LT1
Adamantidis, M; Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D1
Fletcher, JE; Heiman-Patterson, TD; Rosenberg, H; Tahmoush, AJ1
Iaizzo, PA; Klein, W; Lehmann-Horn, F1
Graf, M; Hackl, W; Mauritz, W; Sluga, E; Sporn, P; Steinbereithner, K1
Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D1
Broennle, AM; Larach, DR; Larach, MG; Rosenberg, H1
Henriksson, KG; Lennmarken, C; Rutberg, H1
Fishbein, WN; Muldoon, SM; Nagarajan, K; Pezeshkpour, G1
Ording, H; Skovgaard, LT2
Fukumitsu, K; Hayashi, Y; Sumikawa, K; Yoshiya, I1
Souza, MR; Suarez-Kurtz, G; Sudo, RT; Zapata, G1
Blomquist, S; Fletcher, R; Ranklev, E1
Amaha, K; Fudeta, H; Iwatsuki, N; Shiozawa, S; Shiratori, T1
Anwyl, R; Bruton, JD; McLoughlin, JV1
Fletcher, R; Ranklev, E1
Gascard, JP; Kozak-Reiss, G; Redouane-Bénichou, K1
Biscardi, HM; Condon, BF; Muldoon, SM1
Fletcher, JE; Rosenberg, H2
Britt, BA; Scott, EA1
Suarez-Kurtz, G; Sudo, RT1
Fletcher, TF; Gallant, EM; Goettl, VM; Rempel, WE1
Biscardi, H; Bockman, EL; Deuster, PA; Muldoon, SM1
Bell, JG; Su, JY1
Brownell, AK; Littmann, V; Paasuke, RT; Walsh, MP1
Bockman, EL; Deuster, PA; Muldoon, SM1
Fishbein, WN1
Fletcher, R; Krantz, P; Ranklev, E1
Fletcher, R; Monti, M; Ranklev, E1
Dozier, SE; Fulfer, RT; Ilias, WK; Williams, CH1
Armbrustmacher, VW; Deuster, PA; Fishbein, WN; Muldoon, SM1
Britt, BA; Haist, C; Kalow, W; Terreau, ME1
Hall, GM; Lister, D1
Vesell, ES1
Denborough, MA; Moulds, RF3
Ellis, FR; Harriman, DG; Keaney, NP1
Bull, AB; Harrison, GG1
Bianchi, CP; Strobel, GE1
Tollefson, G1
Caroff, S; Gerber, JC; Rosenberg, H1
Fletcher, JE; Hilf, M; Rosenberg, H1
Dhalla, NS; Ganguly, PK; Lamers, JM; Sulakhe, PV1
Arnett, DW; Flewellen, EH; Nelson, TE1
Fletcher, R; Ording, H; Ranklev, E1
Becker, MJ; Eng, GD; Muldoon, SM1
Kruse, H; Rössner, M; Siegemund, G1
Reed, S; Rosenberg, H1
Giger, U; Kaplan, RF1
Flewellen, EH; Gloyna, DF; Nelson, TE1
Ellis, FR; Halsall, PJ1
Anderson, IL; Dunlop, DJ; Rawstron, RE1
Sporn, P1
Gallant, EM; Godt, RE; Gronert, GA1
Brownell, AK; Szabo, M1
Biesel, C; Mortier, W1
Britt, BA; Clements, MJ; Endrenyi, L; Frodis, W; Scott, E1
Kurebayashi, N; Ogawa, Y1
Gronert, GA; Onofrio, BM; Thompson, RL1
Su, JY1
Chausmer, AB; Nelson, TE1
Denborough, MA; Sullivan, JS1
Britt, BA; Endrenyi, L; Frodis, W; Scott, E1
Gronert, GA1
Britt, BA; Huckell, VF; Mambo, NC; McEwan, PM; McLaughlin, PR; Morch, JE; Silver, MD1
Coleman, AW; Coleman, JR1
Hori, M; Kamada, T; Kimura, Y; Kuzuya, T; Nishida, K; Otsu, K; Tada, M1
Lynch, C; Pancrazio, JJ1
Fletcher, JE; Hubert, M; Levitt, RC; Rosenberg, H; Tripolitis, L; Vita, GM1
Hofer, BO; Sivarajan, M; Su, JY1
Becker, K; Köchling, A; Lenzen, C; Roewer, N; Scholz, J; Schulte am Esch, J; Singh, S; Steinfath, M; Wappler, F1
Beech, J; Dawso, T; Fletcher, JE; Lindborg, S; Tripolitis, L1
Fujita, S; Namba, H; Namiki, A; Notsuki, E; Tsuchida, H; Yamakage, M1
Greim, C; Roewer, N; Rumberger, E; Schulte am Esch, J1
Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N1
Adnet, P; Adnet-Bonte, C; Bello, N; Etchrivi, T; Krivosic-Horber, R; Lestavel, P; Reyford, H; Saulnier, F; Tavernier, B1
Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME1
Boyle, WA; Maher, GM1
Adnet, P; Ducart, A; Krivosic-Horber, R; Renaud, B; Riou, B1
Dickinson, PJ; Sullivan, M1
Davidson, BA; Knight, PR; Smith, MD1
Anetseder, M; Hartung, E; Klepper, S; Reichmann, H1
Fletcher, JE; O'Flynn, RP; Rosenberg, H; Shutack, JG1
Censier, K; Drewe, J; Kaufmann, MA; Urwyler, A1
Hatano, Y; Kakuyama, M; Mori, K; Nakamura, K; Nishiwada, M; Terasako, K; Toda, H1
Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Krivosic, I; Krivosic-Horber, RM; Medahoui, H; Reyford, HG1
Nelson, TE; Wedel, DJ1
Breucking, E; Mortier, W1
Kaus, SJ; Rockoff, MA1
Lenzen, C; Roewer, N; Rumberger, R; Scholz, J; Schulte am Esch, J; Steinfath, M; Wappler, F1
Badenhorst, M; Isaacs, H1
Beech, J; Braund, K; Fletcher, JE; Lindborg, S; Lizzo, F; Tripolitis, L1
Benabid, AL; Bosson, JL; Bourdon, L; Jacquot, C; Le Bas, JF; Payen, JF; Stieglitz, P1
Bourdon, L; Canini, F1
Blackwell, KE; Wackym, PA1
Bose, D; Greenberg, CR; MacLennan, DH; Patel, L; Phillips, MS; Serfas, KD; Wrogemann, K1
Antognini, JF; Chun, K; Gronert, GA; Hwang, F1
Fehr, DM; Larach, DR; Schuler, HG; Zangari, KA1
Akata, T; Boyle, W1
Camu, F; Christiaens, F; D'Haese, J; Gepts, E1
Anetseder, M; Engelhardt, W; Hartung, E; Hogrefe, G; Koob, M; Krauspe, R; Schoemig, P1
Braune, H; Köchling, A; Reissinger, T; Roewer, N; Schulte am Esch, J; Wappler, F1
Sessler, DI1
Herland, J; Julian, FJ; Stephenson, DG1
Badenhorst, M; Brooksbank, R; Isaacs, H; Savage, N1
duBell, WH; Rice, RT; Spurgeon, HA; Wheeler, DM1
Bendahan, D; Confort-Gouny, S; Cozzone, PJ; Kozak-Ribbens, G1
Lamb, GD; Owen, VJ; Taske, NL1
Ellis, FR; Halsall, PJ; Hopkins, PM; Stewart, AD1
Hatano, Y; Kakuyama, M; Maeda, H; Mori, K; Nakamura, K; Tachibana, T; Yamamoto, M1
Engel, AG; Wedel, DJ; Weglinski, MR1
Berg, K; Fagerlund, TH; Islander, G; Ranklev-Twetman, E1
Antognini, JF; Gronert, GA1
Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K1
Bachand, M; Boisvert, M; Chartrand, D; Mayer, FM; Vachon, N1
Berg, K; Fagerlund, TH; Islander, G; Ranklev Twetman, E1
Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A1
Bittner, RE; Gilly, H; Mader, N1
Brancadoro, V; Cozzolino, S; Ellis, FR; Glauber, V; Gonano, EF; Halsall, PJ; Hartung, E; Heffron, JJ; Heytens, L; Kozak-Ribbens, G; Kress, H; Krivosic-Horber, R; Lehmann-Horn, F; Mortier, W; Nivoche, Y; Ording, H; Ranklev-Twetman, E; Sigurdsson, S; Snoeck, M; Stieglitz, P; Tegazzin, V; Urwyler, A; Wappler, F1
Bendixen, D; Fagerlund, T; Gardi, T; Glahn, K; Ording, H1
Demaurex, N; Grinstein, S; MacLennan, DH; McCarthy, TV; Oyamada, H; Tong, J1
Dulhunty, AF; Junankar, PR; Lamb, GD; Laver, DR; Owen, VJ; Taske, NL1
Ben Abraham, R; Glauber, V; Perel, A; Zweig, A1
Kern, C; Moser, N; Roesslein, R; Sutter, PM; Ummenhofer, W; Urwyler, A1
Collins, SP; Mendes, LS1
Bendixen, D; Berg, K; Fagerlund, TH; Islander, G; Ording, H; Ranklev Twetman, E1
Allen, GC; Kunselman, AR; Larach, MG1
Adnet, P; Ben Abraham, R; Glauber, V; Perel, A1
Ashida, K; Azukari, K; Kasamatsu, Y; Ohsawa, A; Osada, M; Yoshioka, K1
Su, JY; Tang, LJ1
Köchling, A; Schulte am Esch, JS; Wappler, F; Winkler, G1
Barone, V; Bracco, A; Cozzolino, S; Di Martino, A; Intravaia, E; Massa, O; Sorrentino, V; Tegazzin, V1
Giblin, L; Heffron, JJ; Lehane, M; Lynch, PJ; MacLennan, DH; Mallet, A; McCarthy, TV; Tong, J; Vaughan, P; Zafra, G1
Montes, A; Puig, MM; Ramos, R; Silva, T; Trillo, L1
Adnet, PJ; Fletcher, JE; Reyford, H; Rosenberg, H; Stewart, SL; Wieland, SJ1
Islander, G; Twetman, ER1
Adnet, PJ; Diallo, A; Etchrivi, TS; Haudecoeur, G; Krivosic-Horber, RM; Tavernier, B1
Balog, EM; Gallant, EM; Lentz, LR; Mickelson, JR; Valberg, SJ1
Antognini, JF; Gronert, GA; Melton, AT1
Fiege, M; Richter, A; Scholz, J; Schulte am Esch, J; Steinfath, M; Wappler, F; Weisshorn, R1
Adnet, P; Krivosic-Horber, R; Reyford, H; Tavernier, B1
Dériaz, O; Frascarolo, P; Freymond, D; Jéquier, E; Reiz, S; Urwyler, A1
Bendixen, D; Islander, G; Ording, H; Ranklev-Twetman, E1
am Esch, JS; Krause, T; Martens, U; Scholz, J; Steinrücke, K; Wappler, F1
Bahia, VS; Marchiori, PE; Oliveira, RA; Scaff, M; Silva, HC; Tsanaclis, AM1
Fardeau, M; Lerale, J; Lunardi, J; MacLennan, DH; Monnier, N; Nivoche, Y; Qi, D; Romero, NB1
Baur, CP; Froeba, G; Georgieff, M; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F; Marx, T; Schoch, E1
Deutrich, C; Froster, UG; Olthoff, D; Rueffert, H; Thamm, B1
Aubert, M; Bendahan, D; Confort-Gouny, S; Cozzone, PJ; Figarella-Branger, D; Ghattas, B; Kozak-Ribbens, G1
Bina, S; Karan, SM; Lojeski, EW; Mongan, PD; Muldoon, SM1
Hurtevent, JF; Krivosic-Horber, R; Maurage, CA; Moerman, A; Pellissier, JF; Stojkovic, T; Vermersch, P1
Deutrich, C; Froster, UG; Olthoff, D; Rueffert, H1
Censier, K; Girard, T; Mueller, CR; Treves, S; Urwyler, A; Zorzato, F1
Antognini, JF; Muldoon, S; Rosenberg, H1
Deutrich, C; Froster, UG; Meinecke, CD; Olthoff, D; Rueffert, H1
Brooks, C; Brown, SL; Ellis, FR; Halsall, PJ; Hopkins, PM; Quinnell, RJ; Robinson, RL; Shaw, MA1
Fiege, M; Schulte Am Esch, J; Steinfath, M; Ulrich Gerbershagen, M; Wappler, F; Weisshorn, R1
Bendixen, D; Islander, G; Ording, H; Ranklev Twetman, E1
Allen, PD; López, JR1
Bina, S; Brandom, BW; Daly, JW; Gallagher, KL; Holman, SJ; Hosoi, E; Muldoon, S; Pudimat, PA; Sei, Y; Venzon, DJ; Wyre, HW1
Asai, T; Ikeda, H; Kusudo, K; Murase, K; Takenoshita, M1
Bina, S; Holman, S; Muldoon, SM1
Du, G; Kraev, A; Kraev, N; Loke, JC; MacLennan, DH; Patel, L; Sharma, P1
Anetseder, M; Baur, CP; Censier, K; Doetsch, S; Felleiter, P; Fiege, M; Fricker, R; Halsall, PJ; Hartung, E; Heffron, JJ; Heytens, L; Hopkins, PM; Klingler, W; Lehmann-Horn, F; Nivoche, Y; Schulte am Esch, J; Tegazzin, V; Tzanova, I; Urwyler, A; Wappler, F; Weisshorn, R1
Duke, AM; Hopkins, PM; Steele, DS1
Koenig, F; Olthoff, D; Rueffert, H; Wehner, M2
Deutrich, C; Froster, UG; Olthoff, D; Rueffert, H; Schober, R1
Muldoon, SM; Nelson, TE; Rosenberg, H1
Censier, K; Ginz, HF; Girard, T; Urwyler, A1
Gillmeister, I; Hommann, M; Schummer, C; Schummer, W1
Bendahan, D; Cozzone, PJ; Ghattas, B; Guis, S; Kozak-Ribbens, G; Lunardi, J; Mattei, JP; Monnier, N1
Duke, AM; Halsal, JP; Hopkins, PM; Steele, DS1
Litman, RS; Rosenberg, H1
De La Corte, FD; Dranchak, PK; Ekenstedt, K; Gallant, EM; MacLeay, JM; McKenzie, EC; Mickelson, JR; Onan, GW; Valberg, SJ1
Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S1
Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F1
Gerbershagen, MU; Wappler, F1
Duke, AM; Steele, DS1
Anetseder, M; Müller, R; Roewer, N; Schuster, F; Tas, P1
Guo, XY; Huang, YG; Luo, AL; Ren, HZ; Wang, YL; Xu, ZH; Ye, TH; Zhang, X1
Bodelsson, M; Islander, G; Ranklev, E; Rydenfelt, K1
Bina, S; Bünger, R; Muldoon, S1
Bross, T; Steinmann, D1
Ortiz Gómez, JR1
Guo, XY; Huang, YG; Luo, AL; Wang, YL; Xu, ZH1
Anetseder, M; Hager, M; Metterlein, T; Muellenbach, RM; Roewer, N; Schuster, F; Wunder, C; Wurmb, T1
Anetseder, M; Kranke, P; Metterlein, T; Muellenbach, RM; Negele, S; Roewer, N; Schuster, F; Schwemmer, U1
Kaufmann, A; Kraft, B; Michalek-Sauberer, A; Weigl, LG1
Parness, J1
Canato, M; Dainese, M; Dirksen, RT; Lyfenko, AD; Paolini, C; Protasi, F; Quarta, M; Reggiani, C1
Booms, P; Carpenter, D; Casson, F; Halsall, PJ; Hogg, M; Hopkins, PM; Iles, DE; Quinnell, RJ; Ringrose, C; Robinson, RL; Shaw, MA; Steele, DS1
Finsterer, J; Höftberger, R; Michalek-Sauberer, A1
Anetseder, M; Kranke, P; Metterlein, T; Roewer, N; Schuster, F1
Carpenter, D; Halsall, PJ; Hopkins, PM; Leo, V; Morris, A; Ringrose, C; Robinson, RL; Shaw, MA1
Amoedo, ND; Cunha, LB; Matos, AR; Rumjanek, FD; Sambuughin, N; Sudo, RT; Zapata-Sudo, G1
Hirayama, H; Iwami, M; Kuramoto, H; Masuda, K; Shiina, T; Shima, T; Shimizu, Y; Takewaki, T1
Abreu, AV; Aguiar, MI; Cardoso, LA; Carmo, PL; Cunha, LB; Matos, AR; Sudo, RT; Trachez, MM; Zapata-Sudo, G1
Cui, XL; Guo, XY; Luo, AL; Tan, G; Wang, YL1
Hamada, H; Kawamoto, M; Kobayashi, M; Migita, T; Mukaida, K; Yuge, O1
Anetseder, M; Hartung, E; Metterlein, T; Roewer, N; Schuster, F1
Kaufmann, A; Kraft, B; Kress, HG; Michalek-Sauberer, A; Steinboeck, F; Weigl, LG; Weindlmayr, M1
Fusi, F; Höller, C; Kraft, B; Kress, HG; Lacava, C; Michalek-Sauberer, A; Sgaragli, G; Sipos, E; Weigl, LG1
Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC1
Islander, G; Melberg, A; Rücker, F; Smits, A; Sundblom, J1
Adolph, O; Chaiklieng, S; Hoppe, K; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F1
Hu, C; Kraeva, N; Larach, MG; Massey, C; Riazi, S; Wijeysundera, D1
Croul, S; Keith, J; Kraeva, N; Orlov, D; Riazi, S; Rosen, D1
Stowell, KM1
Hoppe, K; Jäger, H; Klingler, W; Lehmann-Horn, F; Schleip, R1
Kraeva, N; Larach, MG; Riazi, S; Rosenberg, H; Sterling, C; Timmins, MA1
Abriat, A; Bendahan, D; Brégigeon, M; Brosset, C; Canini, F; Duron-Martinaud, S; Figarella-Branger, D; Jouvion, A; Montigon, C; Sagui, E; Zagnoli, F1
Andria, B; Attanasio, C; Bucci, M; Calderone, V; Cantalupo, A; Cirino, G; Di Martino, A; Ianaro, A; Mancini, A; Panza, E; Savoia, G; Vellecco, V1
Johannsen, S; Mögele, S; Müller, CR; Roewer, N; Schneiderbanger, D; Schuster, F; Treves, S1
Alsina, E; Del Blanco, B; Domínguez, A; García, A; Guerrero, JL; Kollmann-Camaiora, A; Yepes, MJ1
Cifra, B; Kraeva, N; Noseworthy, MD; Rayner, TE; Riazi, S; Schneiderman, JE; Thompson, SJ; Wells, GD1
Johannsen, S; Roewer, N; Schick, M; Schuster, F1
Isbary, S; Johannsen, S; Roewer, N; Schuster, F; Türkmeneli, I1
Allen, PD; Diggle, CP; Hopkins, PM; Kaura, V; Lopez, JR1
Figueroa, L; Kraeva, N; Manno, C; Riazi, S; Ríos, E; Toro, S1
Allen, PD; Dirksen, RT; Lopez, JR1
Biesecker, L; Figueroa, L; Hopkins, PM; Ibarra Moreno, CA; Kraeva, N; Riazi, S; Rios, E; Van Petegem, F; Zvaritch, E1
Bin, X; Tang, Z; Wang, B1
Carlson, KJ; Derkay, CS; Koenig, M; Sun, SA; Swan, C1
Figueroa, L; Ibarra-Moreno, CA; Kraeva, N; Manno, C; Riazi, S; Rios, E; Tammineni, ER1
Hopkins, PM1

Reviews

14 review(s) available for halothane and caffeine

ArticleYear
Epidemiology and inheritance of malignant hyperthermia.
    International anesthesiology clinics, 1979,Winter, Volume: 17, Issue:4

    Topics: Adenosine Triphosphate; Caffeine; Creatine Kinase; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Pedigree

1979
Preanesthetic diagnosis of malignant hyperthermia.
    International anesthesiology clinics, 1979,Winter, Volume: 17, Issue:4

    Topics: Adenosine Triphosphate; Caffeine; Cardiac Catheterization; Creatine Kinase; Halothane; Heart; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Radionuclide Imaging; Time Factors

1979
Malignant hyperthermia: relation to other diseases.
    Acta anaesthesiologica Belgica, 1990, Volume: 41, Issue:2

    Topics: Caffeine; Calcium Channels; Diagnosis, Differential; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Neuroleptic Malignant Syndrome; Neuromuscular Diseases

1990
[Screening tests for malignant hyperthermia susceptibility].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Caffeine; Calcium; Cholinesterases; Contracture; Creatine Kinase; Cyclic AMP; Disease Susceptibility; Electrophysiology; Erythrocytes; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles; Platelet Aggregation; Succinylcholine

1989
Standardization of the caffeine halothane muscle contracture test. North American Malignant Hyperthermia Group.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; North America; Societies, Medical

1989
Diagnosis of susceptibility to malignant hyperthermia in man.
    British journal of anaesthesia, 1988, Volume: 60, Issue:3

    Topics: Caffeine; Chemistry, Clinical; Disease Susceptibility; Halothane; Hematologic Tests; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles

1988
Polygenic factors controlling drug response.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Adult; Animals; Antipyrine; Caffeine; Dicumarol; Environment; Ethanol; Female; Genetic Variation; Half-Life; Halothane; Humans; Isoniazid; Male; Metabolic Clearance Rate; Mice; Middle Aged; Nortriptyline; Pharmaceutical Preparations; Phenylbutazone; Pregnancy; Smoking; Twins

1974
Malignant hyperthermia.
    Pediatric clinics of North America, 1994, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Anesthesia; Biopsy; Caffeine; Child; Child, Preschool; Clinical Protocols; Counseling; Halothane; Humans; Male; Malignant Hyperthermia; Patient Education as Topic; Risk Factors

1994
Malignant hyperthermia.
    Postgraduate medical journal, 1998, Volume: 74, Issue:867

    Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Muscle Relaxants, Central

1998
Defective Mg2+ regulation of RyR1 as a causal factor in malignant hyperthermia.
    Archives of biochemistry and biophysics, 2007, Feb-01, Volume: 458, Issue:1

    Topics: Caffeine; Calcium; Cytosol; Halothane; Humans; Magnesium; Malignant Hyperthermia; Muscle, Skeletal; Ryanodine Receptor Calcium Release Channel

2007
[Anesthesia in malignant hyperthermia].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Calcium Signaling; Child; Child, Preschool; Diagnosis, Differential; Genetic Heterogeneity; Genetic Predisposition to Disease; Halothane; Humans; Incidence; Infant; Information Centers; Malignant Hyperthermia; Middle Aged; Monitoring, Intraoperative; Muscle Contraction; Neuromuscular Depolarizing Agents; Preoperative Care; Ryanodine Receptor Calcium Release Channel; Spain

2008
DNA testing for malignant hyperthermia: the reality and the dream.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Biopsy; Caffeine; Calcium Channels; Calcium Channels, L-Type; Computational Biology; Genetic Predisposition to Disease; Genetic Variation; Halothane; Humans; Malignant Hyperthermia; Muscle, Skeletal; Point Mutation; Polymerase Chain Reaction; Ryanodine Receptor Calcium Release Channel; Sequence Analysis, DNA

2014
Clinical protocol for the management of malignant hyperthermia.
    Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Caffeine; Calcium Signaling; Child; Child, Preschool; Clinical Protocols; Critical Care; Dantrolene; Diagnosis, Differential; Disease Management; Female; Halothane; Humans; Infant; Infant, Newborn; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Neuroleptic Malignant Syndrome; Ryanodine Receptor Calcium Release Channel; Serotonin Syndrome

2017
Anesthetics and Cell-Cell Communication: Potential Ca
    International journal of molecular sciences, 2022, Aug-12, Volume: 23, Issue:16

    Topics: Anesthetics; Anesthetics, Inhalation; Caffeine; Calcium; Calmodulin; Cell Communication; Connexins; Gap Junctions; Halothane; Heptanol; Ion Channels; Isoflurane; Theophylline

2022

Trials

5 trial(s) available for halothane and caffeine

ArticleYear
Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Prognosis; Prospective Studies; Registries; Sensitivity and Specificity

1992
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Single-Blind Method

1991
Identification of susceptibility to malignant hyperpyrexia.
    British medical journal, 1974, May-04, Volume: 2, Issue:5913

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Creatine Kinase; Drug Hypersensitivity; Electrocardiography; Electromyography; Female; Halothane; Humans; Male; Malignant Hyperthermia; Microscopy, Electron; Middle Aged; Muscles; Pedigree; Potassium Chloride; Sarcoplasmic Reticulum; Succinylcholine; Temperature

1974
Genotype-phenotype comparison of the Swiss malignant hyperthermia population.
    Human mutation, 2001, Volume: 18, Issue:4

    Topics: Caffeine; DNA Mutational Analysis; Gene Frequency; Genetic Heterogeneity; Genetic Predisposition to Disease; Genetic Testing; Genotype; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Mutation; Phenotype; Polymorphism, Single-Stranded Conformational; Ryanodine Receptor Calcium Release Channel; Switzerland

2001
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:7

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Sensitivity and Specificity

2003

Other Studies

341 other study(ies) available for halothane and caffeine

ArticleYear
Computation of brain-blood partitioning of organic solutes via free energy calculations.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics

1996
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A laboratory animal model for malignant hyperpyrexia.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:1

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Caffeine; Disease Models, Animal; Drug Interactions; Halothane; Hydrogen-Ion Concentration; Male; Malignant Hyperthermia; Pentobarbital; Rabbits; Time Factors

1979
Isometric contraction of skeletal muscle of malignant hyperthermia (MH) susceptible and resistant Belgian landrace pigs under the influence of several drugs.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1978, Volume: 25, Issue:7

    Topics: Animals; Caffeine; Halothane; Hypothermia; Hypothermia, Induced; In Vitro Techniques; Muscle Contraction; Swine; Swine Diseases

1978
Malignant hyperthermia.
    Human genetics. Supplement, 1978, Issue:1

    Topics: Alleles; Anesthesia, General; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscles

1978
Sites and mechanisms of action of halothane on skeletal muscle function in vitro.
    Anesthesiology, 1979, Volume: 50, Issue:4

    Topics: Animals; Caffeine; Diaphragm; Dose-Response Relationship, Drug; Glycerol; Halothane; Male; Muscle Contraction; Muscles; Potassium Chloride; Rats

1979
Identification of susceptibility to malignant hyperpyrexia in swine.
    British journal of anaesthesia, 1979, Volume: 51, Issue:3

    Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Succinylcholine; Swine; Thymol

1979
In vivo neutron activation analysis for bone calcium (INVAA) in malignant hyperthermia susceptible patients.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:2

    Topics: Adult; Age Factors; Bone and Bones; Caffeine; Calcium; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscles; Neutron Activation Analysis; Sex Factors

1979
Does prior dantrolene affect the in vitro diagnosis of malignant hyperthermia susceptibility?
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:6

    Topics: Animals; Biopsy; Caffeine; Dantrolene; Drug Interactions; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine; Time Factors

1979
Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion.
    Texas reports on biology and medicine, 1979, Volume: 38

    Topics: Anesthetics; Animals; Caffeine; Diagnosis, Differential; Disease Models, Animal; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Masseter Muscle; Muscle Contraction; Muscles; Spasm; Succinylcholine; Swine

1979
Effects of halothane on caffeine-induced tension transients in functionally skinned myocardial fibers.
    Pflugers Archiv : European journal of physiology, 1979, May-15, Volume: 380, Issue:1

    Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Myocardium; Rabbits; Sarcoplasmic Reticulum

1979
Is malignant hyperpyrexia muscle denervated?
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:10

    Topics: Animals; Caffeine; Calcium; Evoked Potentials; Female; Halothane; Humans; In Vitro Techniques; Membrane Potentials; Mice; Models, Neurological; Muscle Contraction; Muscle Denervation; Muscles; Muscular Dystrophies; Succinylcholine

1977
Screening for malignant hyperpyrexia.
    British journal of anaesthesia, 1977, Volume: 49, Issue:2

    Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Mass Screening; Muscle Contraction

1977
The adenosine triphosphate (ATP) depletion test: comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility.
    Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:6

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Biopsy; Caffeine; Carbon Dioxide; Child; Dose-Response Relationship, Drug; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Tonus; Muscles; Oxygen

1976
Porcine malignant hyperthermia: effects of temperature and extracellular calcium concentration on halothane-induced contracture of susceptible skeletal muscle.
    Anesthesiology, 1975, Volume: 42, Issue:3

    Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Swine; Temperature; Time Factors; Transducers

1975
An evaluation of procaine in the treatment of malignant hyperpyrexia.
    British journal of anaesthesia, 1975, Volume: 47, Issue:1

    Topics: Anesthesia, General; Animals; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Evaluation; Halothane; Humans; In Vitro Techniques; Lidocaine; Male; Malignant Hyperthermia; Muscle Contraction; Perfusion; Procaine; Rats

1975
Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle.
    Anesthesiology, 1976, Volume: 44, Issue:1

    Topics: Animals; Caffeine; Calcium; Contracture; Dantrolene; Halothane; Hydantoins; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Sarcoplasmic Reticulum; Swine

1976
Oxygen consumption by human and rodent striated muscle in vitro.
    The American journal of physiology, 1976, Volume: 230, Issue:1

    Topics: Animals; Biological Transport, Active; Caffeine; Diaphragm; Halothane; Humans; In Vitro Techniques; Insulin; Muscles; Osmolar Concentration; Ouabain; Oxygen Consumption; Potassium; Rats; Sodium

1976
W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:2

    Topics: Animals; Caffeine; Calcium; Calmodulin; Dantrolene; Drug Synergism; Halothane; Intercellular Signaling Peptides and Proteins; Malignant Hyperthermia; Muscle Contraction; Peptides; Sulfonamides; Swine; Wasp Venoms

1992
Left ventricular hypertrophy in rabbits does not exaggerate the effects of halothane on the intracellular components of cardiac contraction.
    Anesthesiology, 1992, Volume: 77, Issue:3

    Topics: Animals; Body Weight; Caffeine; Calcium; Cardiomegaly; Halothane; Male; Myocardial Contraction; Organ Size; Rabbits; Sarcoplasmic Reticulum

1992
Sources of variability in halothane and caffeine contracture tests for susceptibility to malignant hyperthermia.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Aged; Caffeine; Child; Contracture; Dose-Response Relationship, Drug; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscles; Sensitivity and Specificity; Time Factors

1992
Na(+)-Ca2+ exchange influences halothane and caffeine contractures of malignant hyperthermic skeletal muscle.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 77, Issue:2

    Topics: Animals; Caffeine; Calcium; Carrier Proteins; Culture Media; Halothane; Kinetics; Malignant Hyperthermia; Membrane Proteins; Muscle Contraction; Muscles; Sodium; Sodium-Calcium Exchanger; Swine

1992
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
    Laboratory animal science, 1992, Volume: 42, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predisposition to Disease; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Species Specificity; Succinylcholine

1992
Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?
    British journal of anaesthesia, 1992, Volume: 69, Issue:5

    Topics: Caffeine; Culture Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Phenotype

1992
Propofol anaesthesia in malignant hyperpyrexia susceptible swine.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:3

    Topics: Anesthesia; Animals; Caffeine; Female; Halothane; Injections, Intravenous; Male; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Propofol; Swine

1992
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles; Propofol

1992
[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:5

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Leukocytes, Mononuclear; Malignant Hyperthermia; Models, Biological; Ryanodine

1992
Abnormal rapid Ca2+ release from sarcoplasmic reticulum of malignant hyperthermia susceptible pigs.
    Biochimica et biophysica acta, 1991, May-07, Volume: 1064, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Biological Transport; Caffeine; Calcium; Calcium Channels; Filtration; Halothane; Kinetics; Magnesium; Malignant Hyperthermia; Ryanodine; Sarcoplasmic Reticulum; Swine

1991
Interactions of fatty acids with the calcium release channel in malignant hyperthermia.
    Advances in experimental medicine and biology, 1991, Volume: 301

    Topics: Animals; Caffeine; Calcium Channels; Fatty Acids; Halothane; Horses; Humans; Isoproterenol; Lipase; Malignant Hyperthermia; Muscle Proteins; Phenytoin; Ryanodine; Succinylcholine; Swine; Triglycerides

1991
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia.
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Military Personnel; Muscle Contraction; Muscles; Muscular Diseases; Physical Exertion; Ryanodine

1991
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
    British journal of anaesthesia, 1990, Volume: 65, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Caffeine; Disease Susceptibility; Drug Synergism; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction

1990
BAY K 8644 and nifedipine alter halothane but not caffeine contractures of malignant hyperthermic muscle fibers.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Swine

1991
Effects of BAY K 8644, nifedipine, and low Ca2+ on halothane and caffeine potentiation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Drug Synergism; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Nifedipine; Swine

1991
Is resting membrane potential a possible indicator of viability of muscle bundles used in the in vitro caffeine contracture test?
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Caffeine; Electric Stimulation; Halothane; Humans; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscles

1992
In vitro contracture tests in patients with various neuromuscular diseases.
    British journal of anaesthesia, 1992, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Disease Susceptibility; Drug Hypersensitivity; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Neuromuscular Diseases; Sensory Thresholds

1992
Halothane alters control of intracellular Ca2+ mobilization in single rat ventricular myocytes.
    Anesthesiology, 1991, Volume: 75, Issue:6

    Topics: Animals; Caffeine; Calcium; Electric Stimulation; Female; Halothane; Heart Ventricles; Myocardial Contraction; Myocardium; Potassium; Rats; Rats, Inbred Strains

1991
Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro.
    International journal of experimental pathology, 1991, Volume: 72, Issue:5

    Topics: Animals; Caffeine; Diaphragm; Drug Synergism; Female; Halothane; In Vitro Techniques; Ketamine; Male; Muscle Contraction; Propofol; Rats; Thiopental

1991
Effects of volatile anesthetics on the intracellular Ca2+ concentration in cardiac muscle cells.
    Advances in experimental medicine and biology, 1991, Volume: 301

    Topics: Anesthetics; Animals; Caffeine; Calcium; Cytosol; Electric Stimulation; Enflurane; Female; Fura-2; Halothane; Heart; In Vitro Techniques; Isoflurane; Membranes; Myocardium; Potassium; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1991
Why does halothane relax cardiac muscle but contract malignant hyperthermic skeletal muscle?
    Advances in experimental medicine and biology, 1991, Volume: 301

    Topics: Animals; Caffeine; Calcium; Depression, Chemical; Fura-2; Halothane; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Myocardial Contraction; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Swine

1991
A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia.
    Genomics, 1991, Volume: 11, Issue:3

    Topics: Adolescent; Amino Acid Sequence; Arginine; Base Sequence; Caffeine; Cloning, Molecular; Cysteine; Exons; Female; Halothane; Humans; Male; Malignant Hyperthermia; Molecular Sequence Data; Muscle Proteins; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, Cholinergic; Restriction Mapping; Ryanodine Receptor Calcium Release Channel; White People

1991
[A new emphasis on the diagnosis of malignant hyperthermia using the in vitro contracture test?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Infant; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Retrospective Studies

1991
[Diagnosis of malignant hyperthermia. The platelet test versus the in vitro contracture test].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Blood Platelets; Caffeine; Child; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction

1991
[In vitro diagnosis of malignant hyperpyrexia syndrome].
    Harefuah, 1991, Dec-15, Volume: 121, Issue:12

    Topics: Adult; Caffeine; Dantrolene; Female; Halothane; Hernia, Inguinal; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles

1991
In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.
    Journal of the neurological sciences, 1991, Volume: 105, Issue:1

    Topics: Adult; Caffeine; Calcium; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Pedigree; Rhabdomyolysis

1991
The effect of azumolene on hypercontractility and sarcoplasmic reticulum Ca(2+)-dependent ATPase activity of malignant hyperpyrexia-susceptible porcine skeletal muscle.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:7

    Topics: Animals; Caffeine; Calcium-Transporting ATPases; Dantrolene; Halothane; Imidazoles; Malignant Hyperthermia; Muscle Contraction; Muscle Relaxants, Central; Muscles; Oxazoles; Potassium Chloride; Sarcoplasmic Reticulum

1991
In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Caffeine; Chromatography, Gas; Contracture; Diffusion Chambers, Culture; Disease Susceptibility; Electric Stimulation; Equipment Design; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; Rheology; Spectrophotometry; Time Factors; Transducers

1991
Pharmacogenetics of caffeine and caffeine-halothane contractures in biopsies of human skeletal muscle.
    Pharmacogenetics, 1991, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Child, Preschool; Female; Genetic Variation; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Sex Characteristics

1991
Effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on myocardial force of contraction of malignant hyperthermia susceptible swine.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Isoproterenol; Malignant Hyperthermia; Myocardial Contraction; Phenylephrine; Stimulation, Chemical; Succinylcholine; Swine

1991
Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Administration, Inhalation; Animals; Caffeine; Creatine Kinase; Disease Susceptibility; Genotype; Halothane; Heterozygote; Homozygote; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Swine

1991
Malignant hyperthermia: normal muscle calcium uptake and abnormal caffeine and halothane contractures.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: Adult; Biopsy; Caffeine; Calcium; Disease Susceptibility; False Negative Reactions; Female; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles

1991
Negative halothane-caffeine contracture test in mdx (dystrophin-deficient) mice.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:9

    Topics: Abdomen; Animals; Caffeine; Contracture; Drug Combinations; Dystrophin; Halothane; Mice; Mice, Mutant Strains; Osmolar Concentration

1991
Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia.
    Nature, 1990, Feb-08, Volume: 343, Issue:6258

    Topics: Animals; Caffeine; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halothane; Heterozygote; Homozygote; Humans; Lod Score; Male; Malignant Hyperthermia; Muscle Contraction; Mutation; Pedigree; Polymorphism, Restriction Fragment Length; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel; Swine

1990
Calcium handling by platelets from normal and malignant hyperthermia-susceptible pigs.
    Life sciences, 1991, Volume: 48, Issue:15

    Topics: Animals; Biological Transport; Blood Platelets; Caffeine; Calcium; Halothane; Malignant Hyperthermia; Swine

1991
Malignant hyperthermia in dogs.
    Journal of the American Veterinary Medical Association, 1991, Mar-15, Volume: 198, Issue:6

    Topics: Animals; Biopsy; Caffeine; Crosses, Genetic; Dantrolene; Dog Diseases; Dogs; Female; Halothane; Heart Rate; Male; Malignant Hyperthermia; Muscle Contraction; Pedigree

1991
[Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland].
    Schweizerische medizinische Wochenschrift, 1991, Apr-20, Volume: 121, Issue:16

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Caffeine; Child; Female; Genetic Predisposition to Disease; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles

1991
Effects of the anesthetics heptanol, halothane and isoflurane on gap junction conductance in crayfish septate axons: a calcium- and hydrogen-independent phenomenon potentiated by caffeine and theophylline, and inhibited by 4-aminopyridine.
    The Journal of membrane biology, 1991, Volume: 121, Issue:1

    Topics: 4-Aminopyridine; Alcohols; Anesthetics; Animals; Astacoidea; Axons; Caffeine; Calcium; Electric Conductivity; Halothane; Heptanol; Hydrogen-Ion Concentration; Intercellular Junctions; Isoflurane; Kinetics; Membrane Potentials; Theophylline

1991
Molecular genetics and malignant hyperthermia.
    Anesthesiology, 1991, Volume: 75, Issue:1

    Topics: Caffeine; Genetic Markers; Halothane; Humans; Malignant Hyperthermia; Molecular Biology

1991
A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia.
    Anesthesiology, 1991, Volume: 75, Issue:1

    Topics: Alleles; Caffeine; Child; Female; Genetic Linkage; Genetic Markers; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Polymorphism, Genetic; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel

1991
Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Animals; Caffeine; Calcium; Cytosol; Disease Susceptibility; Egtazic Acid; Halothane; Humans; Malignant Hyperthermia; Monocytes; Muscle Contraction; Muscles; Swine; Swine Diseases

1990
[Do neuroleptic malignant syndrome and malignant hyperthermia of anesthesia share a common mechanism?].
    Presse medicale (Paris, France : 1983), 1990, Sep-29, Volume: 19, Issue:31

    Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Neuroleptic Malignant Syndrome

1990
Microassay for malignant hyperthermia susceptibility: hypersensitive ligand-gating of the Ca channel in muscle sarcoplasmic reticulum causes increased amounts and rates of Ca-release.
    Molecular and cellular biochemistry, 1990, Mar-05, Volume: 93, Issue:1

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Halothane; Ion Channel Gating; Kinetics; Ligands; Malignant Hyperthermia; Sarcoplasmic Reticulum; Swine

1990
The importance of calcium ions for in vitro malignant hyperthermia testing.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Quinacrine; Strontium; Succinylcholine; Verapamil

1990
Inappropriate use of the t-test.
    Anesthesiology, 1990, Volume: 73, Issue:4

    Topics: Animals; Caffeine; Halothane; Malignant Hyperthermia; Statistics as Topic; Swine

1990
Halothane cooling contractures of skinned mammalian muscle fibers.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Action Potentials; Animals; Caffeine; Calcium; Cold Temperature; Halothane; In Vitro Techniques; Lidocaine; Muscle Contraction; Muscles; Procaine; Rabbits; Sarcoplasmic Reticulum

1990
Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia?
    British journal of anaesthesia, 1990, Volume: 65, Issue:5

    Topics: Biopsy; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Myotonia; Paralyses, Familial Periodic

1990
Importance of fasting in the lymphocyte calcium test for malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Aged; Caffeine; Calcium; Contracture; Cytoplasm; Fasting; Female; Halothane; Humans; Lymphocytes; Male; Malignant Hyperthermia; Middle Aged; Muscles

1990
Influence of salbutamol on the in vitro muscle response to caffeine and halothane in malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:8

    Topics: Adult; Albuterol; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Interactions; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscles

1990
Caffeine and halothane contracture testing in swine using the recommendations of the North American Malignant Hyperthermia Group.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine

1990
Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2.
    Nature, 1990, Feb-08, Volume: 343, Issue:6258

    Topics: Animals; Caffeine; Chromosome Mapping; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halothane; Humans; Lod Score; Male; Malignant Hyperthermia; Muscle Contraction; Pedigree; Receptors, Cholinergic; Recombination, Genetic; Ryanodine Receptor Calcium Release Channel; Swine

1990
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
    British journal of anaesthesia, 1990, Volume: 64, Issue:1

    Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Sensory Thresholds; Verapamil

1990
Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility.
    Anesthesiology, 1990, Volume: 72, Issue:4

    Topics: Anesthesia, General; Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia

1990
Malignant hyperthermia in the otolaryngologic patient: prospective anesthetic and surgical management of eight children.
    The Annals of otology, rhinology, and laryngology, 1990, Volume: 99, Issue:4 Pt 1

    Topics: Adenoidectomy; Anesthesia, General; Anxiety; Caffeine; Child; Child, Preschool; Contracture; Female; Halothane; Humans; Infant; Male; Malignant Hyperthermia; Middle Ear Ventilation; Nitrous Oxide; Preanesthetic Medication; Prospective Studies; Tonsillectomy

1990
Contracture test and histologic and histochemical analyses of muscle biopsy specimens from horses with exertional rhabdomyolysis.
    Journal of the American Veterinary Medical Association, 1990, Apr-01, Volume: 196, Issue:7

    Topics: Anesthesia; Animals; Biopsy, Needle; Caffeine; Contracture; Female; Fever; Halothane; Horse Diseases; Horses; Male; Physical Exertion; Rhabdomyolysis

1990
An association between certain congenital abnormalities and the malignant hyperthermia trait.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Jun-02, Volume: 77, Issue:11

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Congenital Abnormalities; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscles

1990
Current diagnostic methods of malignant hyperthermia: an evaluation.
    Acta anaesthesiologica Belgica, 1990, Volume: 41, Issue:2

    Topics: Caffeine; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Magnetic Resonance Spectroscopy; Malignant Hyperthermia; Muscle Contraction

1990
Effects of the calcium antagonist, TMB-8 on halothane and on caffeine contractures of malignant hyperthermia susceptible skeletal muscle.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Caffeine; Calcium Channel Blockers; Gallic Acid; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine

1990
Compensatory increase in calcium extrusion activity of untreated lymphocytes from swine susceptible to malignant hyperthermia.
    American journal of veterinary research, 1990, Volume: 51, Issue:7

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia; Muscle Contraction; Swine; Swine Diseases

1990
Alterations in the functional properties of skinned fibers from denervated rabbit skeletal muscle.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 1

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Denervation; Muscles; Rabbits; Sarcoplasmic Reticulum

1990
Abnormal membrane properties of the sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia: modes of action of halothane, caffeine, dantrolene, and two other drugs.
    Archives of biochemistry and biophysics, 1986, Volume: 247, Issue:2

    Topics: Animals; Caffeine; Calcium; Dantrolene; Electron Spin Resonance Spectroscopy; Halothane; Intracellular Membranes; Malignant Hyperthermia; Microsomes; Permeability; Ruthenium Red; Sarcoplasmic Reticulum; Swine; Tetracaine

1986
Effects of halothane, caffeine, dantrolene and tetracaine on the calcium permeability of skeletal sarcoplasmic reticulum of malignant hyperthermic pigs.
    Biochimica et biophysica acta, 1987, Feb-26, Volume: 897, Issue:2

    Topics: Animals; Caffeine; Calcium; Cell Membrane Permeability; Dantrolene; Halothane; Kinetics; Malignant Hyperthermia; Ruthenium Red; Sarcoplasmic Reticulum; Swine; Tetracaine

1987
Drug-induced Ca2+ release from isolated sarcoplasmic reticulum. II. Releases involving a Ca2+-induced Ca2+ release channel.
    The Journal of biological chemistry, 1987, May-05, Volume: 262, Issue:13

    Topics: Animals; Caffeine; Calcium; Halothane; Ion Channels; Miconazole; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum; Sulfonamides; Tetracaine; Thymol

1987
[Central core disease associated with malignant hyperthermia sensitivity].
    Presse medicale (Paris, France : 1983), 1989, Apr-22, Volume: 18, Issue:16

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Neuromuscular Diseases; Pedigree

1989
Malignant hyperthermia: slow sodium current in cultured human muscle cells.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1

    Topics: Caffeine; Cells, Cultured; Disease Susceptibility; Electric Conductivity; Halothane; Humans; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscles; Sodium Channels

1989
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:8

    Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Neuroleptic Malignant Syndrome

1989
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:10

    Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Verapamil

1989
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
    Der Anaesthesist, 1989, Volume: 38, Issue:12

    Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia; Muscle Contraction

1989
The use of Fura-2 to estimate myoplasmic [Ca2+] in human skeletal muscle.
    Cell calcium, 1989, Volume: 10, Issue:3

    Topics: Benzofurans; Caffeine; Calcium; Chromatography, High Pressure Liquid; Fura-2; Halothane; Humans; In Vitro Techniques; Muscles; Muscular Diseases; Spectrometry, Fluorescence

1989
[Malignant hyperthermia; two cases of MH in the presence of general anesthesia and performing caffeine contracture test].
    Masui. The Japanese journal of anesthesiology, 1989, Volume: 38, Issue:4

    Topics: Adult; Caffeine; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction

1989
The in vitro determination of susceptibility to malignant hyperthermia.
    Muscle & nerve, 1989, Volume: 12, Issue:3

    Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine

1989
31P-NMR spectroscopy: the metabolic profile of malignant hyperpyrexic porcine skeletal muscle.
    Muscle & nerve, 1989, Volume: 12, Issue:5

    Topics: Animals; Caffeine; Halothane; Magnetic Resonance Imaging; Malignant Hyperthermia; Muscles; Phosphorus; Swine

1989
Effects of droperidol, haloperidol and ketamine on halothane, succinylcholine and caffeine contractures: implications for malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:3

    Topics: Animals; Caffeine; Contracture; Droperidol; Haloperidol; Halothane; Humans; Ketamine; Male; Malignant Hyperthermia; Rats; Rats, Inbred Strains; Succinylcholine

1989
Volatile anesthetics decrease calcium content of isolated myocytes.
    Anesthesiology, 1989, Volume: 70, Issue:6

    Topics: Animals; Caffeine; Calcium; Depression, Chemical; Enflurane; Halothane; In Vitro Techniques; Isoflurane; Male; Myocardium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum

1989
Effect of diltiazem and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible porcine skeletal muscle.
    British journal of anaesthesia, 1989, Volume: 62, Issue:5

    Topics: Animals; Caffeine; Dantrolene; Diltiazem; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Swine

1989
Comparison of the effects of halothane on skinned myocardial fibers from newborn and adult rabbit: II. Effects on sarcoplasmic reticulum.
    Anesthesiology, 1989, Volume: 71, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Caffeine; Calcium; Halothane; Heart; In Vitro Techniques; Male; Myocardium; Rabbits; Sarcoplasmic Reticulum

1989
Inhalation anaesthetics decrease calcium content of cardiac sarcoplasmic reticulum.
    British journal of anaesthesia, 1989, Volume: 62, Issue:6

    Topics: Anesthetics; Animals; Caffeine; Calcium; Enflurane; Halothane; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum

1989
Intracellular mechanisms of halothane's effect on isolated aortic strips of the rabbit.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Caffeine; Calcium; Endothelium, Vascular; Halothane; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Perfusion; Potassium Chloride; Rabbits; Sarcoplasmic Reticulum; Vasodilation

1989
Standards for halothane/caffeine contracture test.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

1989
Malignant hyperthermia in humans--standardization of contracture testing protocol.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Drug Combinations; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

1989
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
    The American journal of psychiatry, 1989, Volume: 146, Issue:5

    Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

1989
Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:5

    Topics: Anesthesia; Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles; Propranolol

1989
Effects of the halothane-sensitivity gene on sarcoplasmic reticulum function.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Genes; Halothane; Kinetics; Malignant Hyperthermia; Muscles; Receptors, Cholinergic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Species Specificity; Swine; Swine Diseases

1989
Anaesthetic-induced increase in ionised calcium in blood mononuclear cells from malignant hyperthermia patients.
    Lancet (London, England), 1987, Feb-28, Volume: 1, Issue:8531

    Topics: Aminoquinolines; Anesthetics; Caffeine; Calcium; Drug Evaluation; Halothane; Humans; In Vitro Techniques; Ions; Malignant Hyperthermia; Muscle Contraction

1987
Ca-induced Ca release in malignant hyperthermia-susceptible pig skeletal muscle.
    The American journal of physiology, 1989, Volume: 256, Issue:2 Pt 1

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Kinetics; Malignant Hyperthermia; Muscles; Reference Values; Sarcoplasmic Reticulum; Swine; Swine Diseases

1989
Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus.
    British journal of pharmacology, 1985, Volume: 85, Issue:3

    Topics: Animals; Caffeine; Electrophysiology; Ethanol; Halothane; Hippocampus; In Vitro Techniques; Ketamine; Nitrous Oxide; Pentobarbital; Rats; Synapses; Synaptic Transmission

1985
[Contracture test with ionophore A 23187 for the diagnosis of malignant hyperthermia].
    Annales francaises d'anesthesie et de reanimation, 1986, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Caffeine; Calcimycin; Contracture; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscles

1986
Malignant hyperthermia in plastic surgery.
    Plastic and reconstructive surgery, 1988, Volume: 82, Issue:5

    Topics: Adult; Caffeine; Child; Child, Preschool; Dermoid Cyst; Disease Susceptibility; Facial Neoplasms; Female; Halothane; Humans; Male; Malignant Hyperthermia; Prospective Studies; Succinylcholine; Surgery, Plastic; Tendon Transfer

1988
The effect of halothane on the free intracellular calcium concentration of isolated rat heart cells.
    Anesthesiology, 1988, Volume: 69, Issue:4

    Topics: Aminoquinolines; Animals; Caffeine; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Intracellular Membranes; Male; Myocardium; Osmolar Concentration; Rats; Rats, Inbred Strains

1988
Effect of fiber types, fascicle size and halothane on caffeine contractures in rat muscles.
    Journal of the neurological sciences, 1988, Volume: 88, Issue:1-3

    Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Rats; Rats, Inbred Strains

1988
Calmodulin-antagonist drugs and porcine malignant hyperpyrexia.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:6

    Topics: Animals; Caffeine; Calmodulin; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Phenothiazines; Potassium Chloride; Swine

1988
Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aging; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles; Myofibrils

1988
[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Creatine Kinase; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscles; Risk Factors

1988
Halothane-caffeine contracture testing in neuromuscular diseases.
    Muscle & nerve, 1988, Volume: 11, Issue:5

    Topics: Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; Neuromuscular Diseases; Risk Factors

1988
Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 411, Issue:6

    Topics: Animals; Benzofurans; Caffeine; Calcium; Disease Susceptibility; Fura-2; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Physical Exertion; Swine

1988
[Malignant hyperthermia in Austria. II. A comparison of the results of diagnostic test procedures].
    Der Anaesthesist, 1988, Volume: 37, Issue:7

    Topics: Adult; Caffeine; Creatine Kinase; Disease Susceptibility; Electromyography; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles

1988
Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests.
    British journal of anaesthesia, 1987, Volume: 59, Issue:12

    Topics: Adult; Aged; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Neuroleptic Malignant Syndrome

1987
Prediction of malignant hyperthermia susceptibility by clinical signs.
    Anesthesiology, 1987, Volume: 66, Issue:4

    Topics: Adolescent; Anesthesia, General; Biopsy; Caffeine; Child; Halothane; Humans; Infant; Malignant Hyperthermia; Muscle Contraction; Muscles; Retrospective Studies; Succinylcholine; Sudden Infant Death

1987
Abnormal relaxation rates in subjects susceptible to malignant hyperthermia.
    Acta neurologica Scandinavica, 1987, Volume: 75, Issue:2

    Topics: Adolescent; Adult; Caffeine; Electromyography; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Relaxation; Skin Temperature

1987
Calcium uptake in frozen muscle biopsy sections compared with other predictors of malignant hyperthermia susceptibility.
    Anesthesiology, 1987, Volume: 66, Issue:5

    Topics: Animals; Biopsy; Caffeine; Calcium; Cats; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscles

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: evaluation of tests with halothane-caffeine, potassium chloride, suxamethonium and caffeine-suxamethonium.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Evaluation Studies as Topic; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Potassium Chloride; Succinylcholine

1987
Selective inhibition by dantrolene of caffeine-induced catecholamine release from perfused dog adrenals.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:1

    Topics: Adrenal Glands; Animals; Caffeine; Catecholamines; Dantrolene; Dogs; Female; Halothane; In Vitro Techniques; Male; Perfusion

1987
Halothane-cooling contractures of mammalian muscles.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2

    Topics: Anesthetics, Local; Animals; Caffeine; Calcium; Cold Temperature; Dantrolene; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Mice; Muscle Contraction; Temperature

1986
Static v. dynamic tests in the in vitro diagnosis of malignant hyperthermia susceptibility.
    British journal of anaesthesia, 1986, Volume: 58, Issue:6

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction

1986
[Contracture response to isoflurane and pentazocine in muscles of a patient with malignant hyperthermia].
    Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:3

    Topics: Caffeine; Child; Halothane; Humans; In Vitro Techniques; Isoflurane; Male; Malignant Hyperthermia; Methyl Ethers; Muscle Contraction; Pentazocine

1986
Action of halothane on rat soleus muscle: temperature dependent induction of contractures and modification of caffeine and potassium contractures.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Female; Halothane; In Vitro Techniques; Muscle Contraction; Potassium; Rats; Rats, Inbred Strains; Temperature

1986
Investigation of malignant hyperthermia in Sweden.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Caffeine; Child; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscles; Sweden

1986
[Detection of peranesthetic malignant hyperthermia by muscle contracture tests and NMR spectroscopy].
    Annales francaises d'anesthesie et de reanimation, 1986, Volume: 5, Issue:6

    Topics: Biopsy; Caffeine; Halothane; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Malignant Hyperthermia; Muscle Contraction; Muscles

1986
Diagnosis of malignant hyperthermia: implications for the military.
    Military medicine, 1985, Volume: 150, Issue:6

    Topics: Adolescent; Adult; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Military Medicine; Muscle Contraction; Referral and Consultation

1985
Malignant hyperthermia.
    Hospital practice (Office ed.), 1985, Mar-15, Volume: 20, Issue:3

    Topics: Adult; Anesthesia; Animals; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; Risk; Swine

1985
Masseter muscle rigidity and malignant hyperthermia susceptibility.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:2

    Topics: Caffeine; Child; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter Muscle; Masticatory Muscles; Muscle Contraction; Muscle Rigidity; Succinylcholine

1986
Failure of the platelet-halothane nucleotide depletion test as a diagnostic or screening test for malignant hyperthermia.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:2

    Topics: Blood Platelets; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Nucleotides

1986
The temperature dependence of halothane-induced contractures of skeletal muscle.
    Muscle & nerve, 1986, Volume: 9, Issue:1

    Topics: Anesthetics, Local; Animals; Anura; Caffeine; Calcium; Disease Models, Animal; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Temperature

1986
Porcine malignant hyperthermia: cell injury enhances halothane sensitivity of biopsies.
    Muscle & nerve, 1986, Volume: 9, Issue:2

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Hybridization, Genetic; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Sarcoplasmic Reticulum; Swine

1986
Verapamil and zero Ca2+ alter responses of cat muscle to halothane and caffeine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:3

    Topics: Animals; Caffeine; Calcium; Cats; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Halothane; Muscle Contraction; Muscles; Verapamil

1986
Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Animals; Caffeine; Calcium; Drug Interactions; Halothane; In Vitro Techniques; Isoflurane; Methyl Ethers; Muscle Contraction; Muscle, Smooth; Rabbits; Sarcoplasmic Reticulum

1986
Electrophoresis of muscle proteins is not a method for diagnosis of malignant hyperthermia susceptibility.
    Anesthesiology, 1986, Volume: 64, Issue:4

    Topics: Caffeine; Electrophoresis, Polyacrylamide Gel; Halothane; Humans; Malignant Hyperthermia; Molecular Weight; Muscle Contraction; Muscle Proteins; Sarcoplasmic Reticulum

1986
In vitro responses of cat skeletal muscle to halothane and caffeine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:2

    Topics: Animals; Caffeine; Cats; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Halothane; Hypertension, Malignant; Muscle Contraction; Muscles

1985
Myoadenylate deaminase deficiency: inherited and acquired forms.
    Biochemical medicine, 1985, Volume: 33, Issue:2

    Topics: Adenylate Kinase; Ammonia; AMP Deaminase; Biopsy; Caffeine; Creatine Kinase; Female; Genetic Carrier Screening; Halothane; Homozygote; Humans; Isoenzymes; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Cramp; Muscles; Nucleotide Deaminases; Physical Exertion

1985
Malignant hyperpyrexia and sudden death.
    The American journal of forensic medicine and pathology, 1985, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Caffeine; Death, Sudden; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperthermia; Muscles

1985
In vitro interaction between halothane and succinylcholine in human skeletal muscle: implications for malignant hyperthermia and masseter muscle rigidity.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Masseter Muscle; Masticatory Muscles; Muscle Contraction; Muscle Rigidity; Succinylcholine

1985
Laboratory diagnosis of malignant hyperpyrexia susceptibility (MHS). European MH Group.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia

1985
Microcalorimetric studies in malignant hyperpyrexia susceptible individuals.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Blood Platelets; Body Temperature Regulation; Caffeine; Calorimetry; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles

1985
Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Animals; Benzazepines; Caffeine; Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine; Time Factors

1985
Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: is there a relationship?
    Biochemical medicine, 1985, Volume: 34, Issue:3

    Topics: Adenylate Kinase; Adult; AMP Deaminase; Caffeine; Creatine Kinase; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Nucleotide Deaminases

1985
Metabolic error of muscle metabolism after recovery from malignant hyperthermia.
    Lancet (London, England), 1970, Oct-31, Volume: 2, Issue:7679

    Topics: Adolescent; Adult; Anesthesia, General; Caffeine; Calcium; Contracture; Female; Fever; Halothane; Humans; In Vitro Techniques; Male; Metabolism, Inborn Errors; Muscle Contraction; Muscles

1970
Letter: Procaine and malignant hyperthermia.
    Lancet (London, England), 1974, Feb-09, Volume: 1, Issue:7850

    Topics: Animals; Caffeine; Drug Interactions; Guinea Pigs; Halothane; Malignant Hyperthermia; Muscle Rigidity; Muscles; Procaine

1974
Malignant hyperthermia--an investigation of three patients.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Adenosine Triphosphatases; Anesthesia, General; Aspartate Aminotransferases; Body Temperature; Caffeine; Calcium; Electron Transport; Endoplasmic Reticulum; Fever; Genes, Dominant; Halothane; Humans; Mitochondria, Muscle; Muscle Contraction; Muscle Proteins; Muscles; Myoglobin; Oxidative Phosphorylation; Phosphates; Potassium; Spasm; Succinylcholine

1971
Procaine in malignant hyperpyrexia.
    British medical journal, 1972, Dec-02, Volume: 4, Issue:5839

    Topics: Aged; Caffeine; Female; Halothane; Humans; In Vitro Techniques; Lidocaine; Malignant Hyperthermia; Muscle Contraction; Procaine; Relaxation

1972
Histopathological and neuropharmacological aspects of malignant hyperpyrexia.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:1 Pt 1

    Topics: Adult; Anesthesia, General; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscular Diseases; Procaine

1973
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Models, Animal; Electrolytes; Enzymes; Halothane; Malignant Hyperthermia; Mannitol; Muscles; Procaine; Rats; Sarcoplasmic Reticulum; Succinylcholine; Swine; Tromethamine

1973
Biochemical basis of malignant hyperpyrexia.
    British medical journal, 1974, May-04, Volume: 2, Issue:5913

    Topics: Biopsy; Caffeine; Calcium; Cell Membrane; Creatine Kinase; Extracellular Space; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Models, Biological; Muscle Contraction; Muscles; Potassium Chloride; Procaine; Sarcolemma; Sarcoplasmic Reticulum; Succinylcholine; Temperature

1974
An in-vitro model of anesthetic hypertonic hyperpyrexia, halothane--caffeine-induced muscle contractures: prevention of contracture by procainamide.
    Anesthesiology, 1971, Volume: 35, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Anura; Caffeine; Culture Techniques; Drug Synergism; Fever; Halothane; Lidocaine; Models, Biological; Muscle Contraction; Procainamide; Rana pipiens; Sarcoplasmic Reticulum; Time Factors

1971
A case of neuroleptic malignant syndrome: in vitro muscle comparison with malignant hyperthermia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:4

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscles

1982
Neuroleptic malignant syndrome and malignant hyperthermia.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Fever; Fluphenazine; Halothane; Humans; Muscle Contraction; Syndrome

1983
Effects of midazolam on directly stimulated muscle biopsies from control and malignant hyperthermia positive patients.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Anti-Anxiety Agents; Benzodiazepines; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Midazolam; Muscle Contraction; Muscles; Preanesthetic Medication

1984
Characterization of Ca2+ release from the cardiac sarcoplasmic reticulum.
    General physiology and biophysics, 1983, Volume: 2, Issue:5

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Radioisotopes; Dogs; Ether; Halothane; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Myocardium; Peptide Hydrolases; Phospholipases; Sarcoplasmic Reticulum; Temperature

1983
Prolonged electromechanical coupling time intervals in skeletal muscle of pigs susceptible to malignant hyperthermia.
    Muscle & nerve, 1983, Volume: 6, Issue:4

    Topics: Animals; Caffeine; Disease Models, Animal; Electric Stimulation; Halothane; Kinetics; Malignant Hyperthermia; Muscle Contraction; Muscles; Swine; Synaptic Transmission

1983
Dantrolene does not block calcium pulse-induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle.
    FEBS letters, 1984, Feb-13, Volume: 167, Issue:1

    Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; Ion Channels; Malignant Hyperthermia; Muscle Contraction; Sarcoplasmic Reticulum; Swine

1984
Investigation of malignant hyperthermia in Denmark and Sweden.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Female; Genetic Testing; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles; Surgical Procedures, Operative

1984
A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Biopsy; Caffeine; Disease Susceptibility; Genetic Testing; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Methods; Muscle Contraction; Muscles

1984
Electrodiagnostic tests in the detection of malignant hyperthermia.
    Muscle & nerve, 1984, Volume: 7, Issue:8

    Topics: Adolescent; Adult; Caffeine; Electric Stimulation; Electromyography; Evoked Potentials; Female; Halothane; Humans; Injections, Intramuscular; Male; Malignant Hyperthermia; Muscles; Succinylcholine

1984
Halothane-succinylcholine induced masseter spasm: indicative of malignant hyperthermia susceptibility?
    Anesthesia and analgesia, 1984, Volume: 63, Issue:7

    Topics: Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter Muscle; Masticatory Muscles; Muscle Contraction; Phenotype; Risk; Spasm; Succinylcholine

1984
Thyroliberin (thyrotropin releasing hormone): antagonism of halothane and hexobarbital narcosis in mice. Comparison with pentetrazol, caffeine, d-amphetamine and adrenaline.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:3

    Topics: Animals; Caffeine; Dextroamphetamine; Dose-Response Relationship, Drug; Epinephrine; Halothane; Hexobarbital; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Thyrotropin-Releasing Hormone

1982
In vitro contracture tests for susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:4

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle Rigidity; Muscles

1983
Halothane-induced ATP depletion in platelets from patients susceptible to malignant hyperthermia and from controls.
    Anesthesiology, 1983, Volume: 58, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Blood Platelets; Caffeine; Child; Chromatography, High Pressure Liquid; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Potassium Chloride

1983
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:6

    Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Lactates; Lactic Acid; Malignant Hyperthermia; Muscle Contraction; Phenotype; Preoperative Care; Swine; Swine, Miniature; Thiopental

1983
Is theophylline, aminophylline, or caffeine (methylxanthines) contraindicated in malignant hyperthermia susceptible patients?
    Anesthesia and analgesia, 1983, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aminophylline; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Theophylline; Xanthines

1983
The control of muscle contracture by the action of dantrolene on the sarcolemma.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:3

    Topics: Animals; Caffeine; Dantrolene; Diaphragm; Dinitrophenols; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Rats; Sarcolemma

1983
Screening for malignant hyperthermia susceptibility.
    The New Zealand medical journal, 1980, Jun-11, Volume: 91, Issue:661

    Topics: Caffeine; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Mass Screening; Muscle Contraction; Muscles

1980
[Malignant hyperthermia-results of familial investigations in Austria (author's transl)].
    Wiener klinische Wochenschrift. Supplementum, 1981, Volume: 132

    Topics: Adenosine Triphosphate; Austria; Caffeine; Calcium; Chlorpromazine; Creatine Kinase; Halothane; Humans; In Vitro Techniques; Isoenzymes; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride

1981
Mechanical properties of normal and malignant hyperthemia susceptible porcine muscle: effects of halothane and other drugs.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:1

    Topics: Animals; Anura; Caffeine; Drug Interactions; Epinephrine; Halothane; In Vitro Techniques; Male; Malignant Hyperthermia; Mice; Muscle Contraction; Norepinephrine; Rana pipiens; Succinylcholine; Swine

1980
Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases.
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:1

    Topics: Anesthesia; Caffeine; Child; Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Masseter Muscle; Masticatory Muscles; Muscle Contraction; Muscles; Spasm; Succinylcholine

1982
The in-vitro caffeine contracture test: influence of the muscle histochemical profile on test results.
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:3

    Topics: Animals; Caffeine; Halothane; Histocytochemistry; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Rats

1982
Pharmacological in-vitro studies in malignant hyperthermia in childhood.
    Brain & development, 1982, Volume: 4, Issue:5

    Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Dose-Response Relationship, Drug; Halothane; Humans; Infant; Malignant Hyperthermia; Muscle Contraction; Muscles; Neuromuscular Diseases

1982
Comparison of the caffeine skinned fibre tension (CSFT) test with the caffeine-halothane contracture (CHC) test in the diagnosis of malignant hyperthermia.
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:6

    Topics: Anesthesia; Caffeine; Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Sarcoplasmic Reticulum

1982
The Ca-releasing action of halothane on fragmented sarcoplasmic reticulum.
    Journal of biochemistry, 1982, Volume: 92, Issue:3

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; Procaine; Rabbits; Sarcoplasmic Reticulum; Temperature

1982
Human malignant hyperthermia: awake episodes and correction by dantrolene.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:5

    Topics: Adenosine Triphosphate; Adult; Caffeine; Dantrolene; Fatigue; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Stress, Physiological; Wakefulness

1980
Effects of halothane on functionally skinned rabbit soleus muscle fibers: a correlation between tension transient and 45Ca release.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 388, Issue:1

    Topics: Animals; Caffeine; Calcium; Calcium Radioisotopes; Halothane; Muscle Contraction; Muscle Proteins; Muscles; Rabbits

1980
Calcium content and contracture in isolated muscle of malignant hyperthermia in pigs.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Magnesium; Malignant Hyperthermia; Muscles; Osmolar Concentration; Swine

1981
Temperature dependence of muscle function in malignant hyperpyrexia-susceptible swine.
    British journal of anaesthesia, 1981, Volume: 53, Issue:11

    Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Succinylcholine; Swine; Temperature

1981
Effect of temperature, time and fascicle size on the caffeine contracture test.
    Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:1

    Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Temperature; Time

1980
Contracture responses and energy stores in quadriceps muscle from humans age 7-82 years.
    Human biology, 1980, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Energy Metabolism; Halothane; Humans; Middle Aged; Muscle Contraction

1980
Site of the muscle cell abnormality in swine susceptible to malignant hyperpyrexia.
    British journal of anaesthesia, 1980, Volume: 52, Issue:4

    Topics: Acetylcholine; Animals; Caffeine; Dantrolene; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Potassium Chloride; Swine; Thymol; Tubocurarine

1980
Malignant hyperthermia susceptibility. A light and electron microscopic study of endomyocardial biopsy specimens from nine patients.
    Human pathology, 1980, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Caffeine; Cardiomyopathies; Female; Halothane; Heart Diseases; Humans; Male; Malignant Hyperthermia; Microscopy, Electron; Middle Aged; Myocardial Contraction; Myocardium

1980
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
    The Journal of experimental zoology, 1980, Volume: 212, Issue:3

    Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine; Theobromine; Theophylline

1980
The point mutation Arg615-->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Western; Caffeine; Calcium; Calcium Channels; Cell Line; Cysteine; Drug Hypersensitivity; Gene Library; Halothane; Intracellular Membranes; Malignant Hyperthermia; Mice; Microsomes; Muscle Proteins; Muscles; Point Mutation; Poly A; Rabbits; RNA; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Transfection

1994
Differential anesthetic-induced opening of calcium-dependent large conductance channels in isolated ventricular myocytes.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 429, Issue:1

    Topics: Anesthetics; Animals; Caffeine; Calcium; Guinea Pigs; Halothane; Heart Ventricles; In Vitro Techniques; Ion Channels; Isoflurane; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Ryanodine; Sarcoplasmic Reticulum

1994
Genotype and phenotype relationships for mutations in the ryanodine receptor in patients referred for diagnosis of malignant hyperthermia.
    British journal of anaesthesia, 1995, Volume: 75, Issue:3

    Topics: Anesthetics, Inhalation; Caffeine; Calcium Channels; Central Nervous System Stimulants; DNA Mutational Analysis; Dose-Response Relationship, Drug; Genotype; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle Proteins; Mutation; Phenotype; Ryanodine Receptor Calcium Release Channel

1995
Effects of halothane on calcium(2+)-activated tension of the contractile proteins and calcium(2+) uptake and release by the sarcoplasmic reticulum in skinned human myocardial fibers.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Animals; Buffers; Caffeine; Calcium; Contractile Proteins; Dose-Response Relationship, Drug; Egtazic Acid; Halothane; Heart Ventricles; Humans; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nitrogen; Rabbits; Sarcoplasmic Reticulum

1995
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response.
    Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:1

    Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromosomes, Human, Pair 19; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Point Mutation; Polymorphism, Genetic; Ryanodine; Ryanodine Receptor Calcium Release Channel

1995
Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis.
    Research in veterinary science, 1995, Volume: 58, Issue:3

    Topics: Animals; Caffeine; Calcium; Halothane; Horse Diseases; Horses; Hyperkalemia; Muscle Contraction; Muscle, Skeletal; Paralysis; Phenytoin; Potassium

1995
Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta.
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Caffeine; Calcium; Calcium Channels; Cytosol; Dose-Response Relationship, Drug; Halothane; Isoflurane; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum

1993
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
    The International journal of biochemistry, 1993, Volume: 25, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Swine; Verapamil

1993
Abnormal action potential responses to halothane in heart muscle isolated from malignant hyperthermia-susceptible pigs.
    Anesthesiology, 1995, Volume: 82, Issue:4

    Topics: Action Potentials; Animals; Caffeine; Dose-Response Relationship, Drug; Electric Stimulation; Halothane; Heart; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle, Skeletal; Swine

1995
Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:2

    Topics: Adult; Biopsy; Caffeine; Cocaine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal

1995
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Neuroleptic Malignant Syndrome

1994
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Dantrolene; Disease Susceptibility; Halothane; Humans; Incidence; Infant; Intraoperative Complications; Malignant Hyperthermia; Middle Aged; Muscle, Skeletal; Nerve Block; Retrospective Studies

1995
Endothelium-independent vasoconstricting and vasodilating actions of halothane on rat mesenteric resistance blood vessels.
    Anesthesiology, 1995, Volume: 82, Issue:1

    Topics: Animals; Caffeine; Drug Interactions; Endothelium, Vascular; Halothane; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Ryanodine; Vascular Resistance; Vasoconstriction; Vasodilation

1995
Malignant hyperthermia during sevoflurane administration.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:3

    Topics: Adult; Anesthetics; Caffeine; Disease Susceptibility; Ethers; Female; Halothane; Humans; Malignant Hyperthermia; Methyl Ethers; Sevoflurane

1995
Exercise induced hyperthermia in a racing greyhound.
    The Veterinary record, 1994, Nov-19, Volume: 135, Issue:21

    Topics: Animals; Caffeine; Dog Diseases; Dogs; Exercise Test; Halothane; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Physical Exertion

1994
Effects hypoxia/reoxygenation on intracellular calcium ion homeostasis in ventricular myocytes during halothane exposure.
    Advances in pharmacology (San Diego, Calif.), 1994, Volume: 31

    Topics: Animals; Caffeine; Calcium; Calcium Channels; Cell Hypoxia; Female; Halothane; Heart Ventricles; Homeostasis; Myocardium; Rats; Rats, Sprague-Dawley

1994
Gasoline vapors induce severe rhabdomyolysis.
    Neurology, 1994, Volume: 44, Issue:12

    Topics: Adult; Alcohol Drinking; Automobile Driving; Caffeine; Creatine Kinase; Gasoline; Halothane; Humans; Male; Muscle Contraction; Muscles; Rhabdomyolysis

1994
Masseter muscle rigidity and malignant hyperthermia susceptibility in pediatric patients. An update on management and diagnosis.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter Muscle; Muscle Rigidity; Retrospective Studies

1994
Genetic effects on the variability of the halothane and caffeine muscle contracture tests.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adult; Biopsy; Caffeine; Child; Disease Susceptibility; Family; Fatal Outcome; Female; Halothane; Humans; Infant; Male; Malignant Hyperthermia; Muscle Contraction; Muscles; Pedigree

1994
Halothane and enflurane constrict canine mesenteric arteries by releasing Ca2+ from intracellular Ca2+ stores.
    Anesthesiology, 1994, Volume: 80, Issue:5

    Topics: Animals; Arginine; Caffeine; Calcium; Dogs; Enflurane; Fluorescent Dyes; Fura-2; Halothane; In Vitro Techniques; Indomethacin; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroarginine; Ryanodine; Spectrometry, Fluorescence; Vasoconstriction

1994
Viability criterion of muscle bundles used in the in vitro contracture test in patients with neuromuscular diseases.
    British journal of anaesthesia, 1994, Volume: 72, Issue:1

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscles; Neuromuscular Diseases

1994
Malignant hyperthermia--diagnostic dilemma: false-negative contracture responses with halothane and caffeine alone.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:4

    Topics: Caffeine; Child; False Negative Reactions; Female; Halothane; Humans; Male; Malignant Hyperthermia

1994
[Diagnosis of malignant hyperthermia susceptibility. 1. The significance of in vitro susceptibility tests].
    Der Anaesthesist, 1993, Volume: 42, Issue:10

    Topics: Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Infant; Male; Malignant Hyperthermia; Retrospective Studies

1993
[High purity ryanodine for in vitro diagnosis of malignant hyperthermia].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1993, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Caffeine; Child; Culture Techniques; Dose-Response Relationship, Drug; Female; Halothane; Humans; Isometric Contraction; Male; Malignant Hyperthermia; Middle Aged; Ryanodine

1993
Combined caffeine-halothane test for malignant hyperthermia.
    British journal of anaesthesia, 1993, Volume: 70, Issue:5

    Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

1993
False-negative results with muscle caffeine halothane contracture testing for malignant hyperthermia.
    Anesthesiology, 1993, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Biopsy; Caffeine; Child, Preschool; False Negative Reactions; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscles

1993
Caffeine contractures, twitch characteristics and the threshold for Ca(2+)-induced Ca2+ release in skeletal muscle from horses with chronic intermittent rhabdomyolysis.
    Research in veterinary science, 1993, Volume: 54, Issue:1

    Topics: Animals; Caffeine; Calcium; Female; Halothane; Horse Diseases; Horses; In Vitro Techniques; Male; Muscle Contraction; Muscles; Rhabdomyolysis

1993
Improved noninvasive diagnostic testing for malignant hyperthermia susceptibility from a combination of metabolites determined in vivo with 31P-magnetic resonance spectroscopy.
    Anesthesiology, 1993, Volume: 78, Issue:5

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; Magnetic Resonance Imaging; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscles; Phosphorus

1993
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Neuromuscular Diseases; Ryanodine

1993
On the nature of the link between malignant hyperthermia and exertional heatstroke.
    Medical hypotheses, 1995, Volume: 45, Issue:3

    Topics: Animals; Body Temperature Regulation; Caffeine; Calcium Channels; Disease Models, Animal; Disease Susceptibility; Energy Metabolism; France; Halothane; Heat Stroke; Humans; Malignant Hyperthermia; Military Personnel; Models, Biological; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Physical Exertion; Ryanodine Receptor Calcium Release Channel; Swine

1995
Malignant hyperthermia in the otology patient: the UCLA experience.
    The American journal of otology, 1994, Volume: 15, Issue:3

    Topics: Administration, Inhalation; Adult; Anesthetics; Caffeine; Child; Child, Preschool; Dantrolene; Female; Halothane; Humans; Infant; Male; Malignant Hyperthermia; Middle Ear Ventilation; Muscle Relaxants, Central; Otolaryngology; Otorhinolaryngologic Diseases; Oxygen Consumption

1994
Comparison of the segregation of the RYR1 C1840T mutation with segregation of the caffeine/halothane contracture test results for malignant hyperthermia susceptibility in a large Manitoba Mennonite family.
    Anesthesiology, 1996, Volume: 84, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Disease Susceptibility; Female; Halothane; Heterozygote; Humans; Male; Malignant Hyperthermia; Manitoba; Middle Aged; Muscle Contraction; Muscle, Skeletal; Mutation; Pedigree

1996
Caffeine-halothane accuracy in MH testing.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:8

    Topics: Caffeine; Drug Stability; Drug Storage; Halothane; Humans; Malignant Hyperthermia

1995
Halothane constricts bovine pulmonary arteries by release of intracellular calcium.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Calcium Channel Blockers; Cattle; Halothane; In Vitro Techniques; Potassium; Pulmonary Artery; Vasoconstriction

1996
Dual actions of halothane on intracellular calcium stores of vascular smooth muscle.
    Anesthesiology, 1996, Volume: 84, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Halothane; Muscle, Smooth, Vascular; Procaine; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum

1996
Malignant hyperthermia suggestive hypermetabolic syndrome at emergence from anesthesia.
    Acta anaesthesiologica Belgica, 1995, Volume: 46, Issue:2

    Topics: Caffeine; Child; Creatine Kinase; Diagnosis, Differential; Female; Halothane; Humans; Malignant Hyperthermia; Muscles; Myoglobin; Rhabdomyolysis

1995
Malignant hyperthermia (MH) diagnostics: a comparison between the halothane-caffeine- and the ryanodine-contracture-test results in MH susceptible, normal and control muscle.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Ryanodine

1996
Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma.
    Intensive care medicine, 1996, Volume: 22, Issue:8

    Topics: Adult; Caffeine; Cresols; Dantrolene; Diabetic Coma; Diabetic Ketoacidosis; Fever; Halothane; Humans; Male; Muscle Relaxants, Central

1996
Malignant hyperthermia.
    Acta anaesthesiologica Scandinavica. Supplementum, 1996, Volume: 109

    Topics: Anesthesia, General; Caffeine; Counseling; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Masseter Muscle; Muscle Contraction; Muscle Rigidity; Safety

1996
Rapid cooling contractures in rat skinned myocardium: effects of isoflurane and halothane.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium-Transporting ATPases; Cold Temperature; Halothane; Histological Techniques; Isoflurane; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred Strains; Saponins; Sarcolemma; Sarcoplasmic Reticulum; Time Factors

1996
HSP72 expression in malignant hyperthermia and normal muscle following exposure to caffeine and halothane.
    Muscle & nerve, 1997, Volume: 20, Issue:1

    Topics: Animals; Caffeine; Fever; Halothane; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Muscle, Skeletal

1997
Initial contractile response of isolated rat heart cells to halothane, enflurane, and isoflurane.
    Anesthesiology, 1997, Volume: 86, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Cells, Cultured; Electric Conductivity; Enflurane; Halothane; Heart; Isoflurane; Male; Membrane Potentials; Myocardial Contraction; Patch-Clamp Techniques; Rats; Rats, Wistar

1997
[Definition of a diagnostic score of malignant hyperthermia using P-31 magnetic resonance spectroscopy].
    Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:5

    Topics: Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Magnetic Resonance Spectroscopy; Malignant Hyperthermia; Phosphorus Isotopes; Retrospective Studies

1996
Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Genetic Predisposition to Disease; Genotype; Halothane; Magnesium; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Osmolar Concentration; Swine

1997
An analysis of the predictive probability of the in vitro contracture test for determining susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Probability; Regression Analysis; Ryanodine

1997
Different effects of halothane, isoflurane and sevoflurane on sarcoplasmic reticulum of vascular smooth muscle in dog mesenteric artery.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Dogs; Drug Synergism; Ethers; Halothane; In Vitro Techniques; Isoflurane; Mesenteric Arteries; Methyl Ethers; Muscle, Smooth, Vascular; Sarcoplasmic Reticulum; Sevoflurane; Vasoconstriction

1997
Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Biopsy, Needle; Caffeine; Child; Child, Preschool; Clinical Enzyme Tests; Creatine Kinase; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Infant; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal

1997
Recombination between the postulated CCD/MHE/MHS locus and RYR1 gene markers.
    Clinical genetics, 1996, Volume: 50, Issue:6

    Topics: Alleles; Caffeine; Calcium Channels; Child, Preschool; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Genetic Markers; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Proteins; Myopathies, Nemaline; Pedigree; Recombination, Genetic; Ryanodine Receptor Calcium Release Channel

1996
Effect of temperature variation (22 degrees C-44 degrees C) on halothane and caffeine contracture testing in normal humans.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:5

    Topics: Aged; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Halothane; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Muscle, Skeletal; Temperature

1997
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Sensitivity and Specificity

1997
Clinical reassessment of malignant hyperthermia in Abitibi-Témiscamingue.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Caffeine; Child; Disease Susceptibility; Family Characteristics; Female; Halothane; Humans; Male; Malignant Hyperthermia; Pedigree; Quebec; Risk Assessment

1997
Malignant hyperthermia susceptibility, an autosomal dominant disorder?
    Clinical genetics, 1997, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Caffeine; Calcium Channels; Child; Child, Preschool; Female; Genes, Dominant; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Mutation; Ryanodine Receptor Calcium Release Channel

1997
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients].
    Harefuah, 1997, Jun-15, Volume: 132, Issue:12

    Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Phenotype

1997
Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study.
    British journal of anaesthesia, 1997, Volume: 79, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Disease Susceptibility; Dystrophin; Halothane; Male; Malignant Hyperthermia; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Animal

1997
In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: results of testing patients surviving fulminant MH and unrelated low-risk subjects. The European Malignant Hyperthermia Group.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Biopsy; Caffeine; Child; Child, Preschool; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Risk Factors; Sensitivity and Specificity

1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Ryanodine

1997
Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease.
    The Journal of biological chemistry, 1997, Oct-17, Volume: 272, Issue:42

    Topics: Animals; Caffeine; Calcium; Cell Line; DNA, Complementary; Halothane; Humans; Malignant Hyperthermia; Mutagenesis, Site-Directed; Myopathies, Nemaline; Rabbits; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel

1997
Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.
    Biophysical journal, 1997, Volume: 73, Issue:4

    Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Caffeine; Calcium; Halothane; Humans; In Vitro Techniques; Kinetics; Magnesium; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Osmolar Concentration; Point Mutation; Ryanodine Receptor Calcium Release Channel; Swine; Swine Diseases

1997
The Israeli Diagnostic Center for Malignant Hyperthermia: 7-years' accumulated experience.
    Israel journal of medical sciences, 1997, Volume: 33, Issue:10

    Topics: Academies and Institutes; Adult; Aged; Biopsy; Caffeine; Child; Electromyography; Female; Genetic Predisposition to Disease; Halothane; Humans; Israel; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Patient Selection; Referral and Consultation; Sensitivity and Specificity

1997
Muscle biopsy for malignant hyperthermia screening in children.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1997, Volume: 7, Issue:5

    Topics: Adolescent; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Child; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle, Skeletal

1997
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro.
    Pharmacological research, 1997, Volume: 36, Issue:6

    Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Trifluoperazine

1997
Discordance between malignant hyperthermia susceptibility and RYR1 mutation C1840T in two Scandinavian MH families exhibiting this mutation.
    Clinical genetics, 1997, Volume: 52, Issue:6

    Topics: Anesthesia; Caffeine; Denmark; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Mutation; Pedigree; Phenotype; Ryanodine Receptor Calcium Release Channel; Sensitivity and Specificity; Sweden

1997
The sensitivity and specificity of the caffeine-halothane contracture test: a report from the North American Malignant Hyperthermia Registry. The North American Malignant Hyperthermia Registry of MHAUS.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Caffeine; Contracture; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscles; Registries

1998
Rhabdomyolysis after infection and taking a cold medicine in a patient who was susceptible to malignant hyperthermia.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:2

    Topics: Adult; Caffeine; Chlorpheniramine; Common Cold; Dantrolene; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Nonprescription Drugs; Phenylephrine; Phenylpropanolamine; Rhabdomyolysis; Virus Diseases

1998
Effects of halothane on the sarcoplasmic reticulum Ca2+ stores and contractile proteins in rabbit pulmonary arteries.
    Anesthesiology, 1998, Volume: 88, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Contractile Proteins; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Dyes; Fura-2; Halothane; Male; Myosin Light Chains; Pulmonary Artery; Rabbits; Sarcoplasmic Reticulum

1998
Rhabdomyolysis following severe physical exercise in a patient with predisposition to malignant hyperthermia.
    Anaesthesia and intensive care, 1998, Volume: 26, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Exercise; Halothane; Heat Stroke; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Rhabdomyolysis; Risk Factors

1998
Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families.
    Journal of medical genetics, 1999, Volume: 36, Issue:2

    Topics: Caffeine; DNA Primers; Female; Halothane; Humans; Italy; Male; Malignant Hyperthermia; Muscles; Myopathies, Nemaline; Pedigree; Point Mutation; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Ryanodine Receptor Calcium Release Channel

1999
A mutation in the transmembrane/luminal domain of the ryanodine receptor is associated with abnormal Ca2+ release channel function and severe central core disease.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-30, Volume: 96, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Caffeine; Calcium; Cell Line; Chromosome Mapping; Cloning, Organism; DNA, Complementary; Female; Genetic Markers; Genotype; Halothane; Humans; Male; Mexico; Mutagenesis, Site-Directed; Myopathies, Nemaline; Pedigree; Point Mutation; Polymorphism, Genetic; Rabbits; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel; Transfection

1999
[Malignant hyperthermia: difficulty in diagnosing susceptibility in Spain].
    Revista espanola de anestesiologia y reanimacion, 1999, Volume: 46, Issue:3

    Topics: Anesthetics, Inhalation; Caffeine; Europe; Genetic Predisposition to Disease; Halothane; Humans; Infant; Intraoperative Complications; Male; Malignant Hyperthermia; Osteomyelitis; Registries; Societies, Medical; Spain

1999
ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine.
    Anesthesiology, 1999, Volume: 90, Issue:5

    Topics: Animals; Caffeine; Cnidarian Venoms; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium Channels

1999
Comparison between the European and North American protocols for diagnosis of malignant hyperthermia susceptibility in humans.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:5

    Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensitivity and Specificity

1999
Effects of halothane on mechanical response of skeletal muscle from malignant hyperthermia susceptible patients.
    Archives of physiology and biochemistry, 1998, Volume: 106, Issue:4

    Topics: Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscle, Skeletal

1998
Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis.
    American journal of veterinary research, 1999, Volume: 60, Issue:8

    Topics: Anesthetics, Inhalation; Animals; Biopsy; Caffeine; Central Nervous System Stimulants; Female; Halothane; Horse Diseases; Horses; Male; Malignant Hyperthermia; Membrane Potentials; Muscle Contraction; Muscle, Skeletal; Pedigree; Physical Exertion; Potassium; Recurrence; Regression Analysis; Rhabdomyolysis

1999
Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:7

    Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Contracture; Dose-Response Relationship, Drug; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter Muscle; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Sarcolemma

1999
5-HT2 receptor antagonist-mediated inhibition of halothane-induced contractures in skeletal muscle specimens from malignant hyperthermia susceptible patients.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Child; Dose-Response Relationship, Drug; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Ritanserin; Serotonin Antagonists; Time Factors

1999
The effect of halothane on calcium release from human skinned masseter fiber is not an artifact.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:5

    Topics: Anesthetics, Inhalation; Artifacts; Caffeine; Calcium; Central Nervous System Stimulants; Halothane; Humans; Masseter Muscle; Muscle Fibers, Skeletal

2000
In vivo whole-body resting energy expenditure and insulin action in human malignant hyperthermia.
    Anesthesiology, 2000, Volume: 93, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Basal Metabolism; Body Composition; Caffeine; Calorimetry, Indirect; Central Nervous System Stimulants; Fasting; Female; Glucose; Halothane; Humans; Insulin; Linear Models; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Patch-Clamp Techniques

2000
Between-center variability of results of the in vitro contracture test for malignant hyperthermia susceptibility.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Caffeine; Female; Genetic Predisposition to Disease; Halothane; Humans; In Vitro Techniques; Leg; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Risk Factors

2000
Inositol 1,4,5-trisphosphate synthesis in mononuclear white blood cells of malignant hyperthermia-susceptible and normal human beings, following in vitro exposure to halothane, caffeine and ryanodine.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:6

    Topics: Anesthetics, Inhalation; Caffeine; Cell Separation; Halothane; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Malignant Hyperthermia; Muscle Contraction; Neutrophils; Phosphodiesterase Inhibitors; Respiratory Muscles; Ryanodine

2000
[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:3A

    Topics: Adult; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Neuroleptic Malignant Syndrome

2000
An autosomal dominant congenital myopathy with cores and rods is associated with a neomutation in the RYR1 gene encoding the skeletal muscle ryanodine receptor.
    Human molecular genetics, 2000, Nov-01, Volume: 9, Issue:18

    Topics: Amino Acid Substitution; Caffeine; Calcium; Cell Line; DNA Mutational Analysis; Female; France; Genes, Dominant; Genetic Heterogeneity; Genetic Predisposition to Disease; Genetic Testing; Genotype; Halothane; Haplotypes; Humans; Lod Score; Male; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Myopathy, Central Core; Pedigree; Polymorphism, Genetic; Ryanodine Receptor Calcium Release Channel

2000
Xenon does not induce contracture in human malignant hyperthermia muscle.
    British journal of anaesthesia, 2000, Volume: 85, Issue:5

    Topics: Anesthetics, Inhalation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genetic Predisposition to Disease; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Phosphodiesterase Inhibitors; Xenon

2000
Homozygous and heterozygous Arg614Cys mutations (1840C-->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family.
    British journal of anaesthesia, 2001, Volume: 87, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Caffeine; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genotype; Halothane; Heterozygote; Homozygote; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Pedigree; Phenotype; Point Mutation; Ryanodine Receptor Calcium Release Channel

2001
A noninvasive investigation of muscle energetics supports similarities between exertional heat stroke and malignant hyperthermia.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:3

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Energy Metabolism; Halothane; Heat Stroke; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Phosphates; Phosphocreatine

2001
Prolonging viability of swine muscle biopsy specimens in malignant hyperthermia testing.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Cold Temperature; Electric Stimulation; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Swine; Tissue Preservation

2001
Congenital myopathy with central cores and fingerprint bodies in association with malignant hyperthermia susceptibility.
    Neuromuscular disorders : NMD, 2001, Volume: 11, Issue:6-7

    Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Halothane; Humans; In Vitro Techniques; Inclusion Bodies; Male; Malignant Hyperthermia; Microscopy, Electron; Muscle Contraction; Muscle Fibers, Skeletal; Myopathy, Central Core; Nuclear Family

2001
Determination of a positive malignant hyperthermia (MH) disposition without the in vitro contracture test in families carrying the RYR1 Arg614Cys mutation.
    Clinical genetics, 2001, Volume: 60, Issue:2

    Topics: Caffeine; DNA; DNA Mutational Analysis; Family Health; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Mutation, Missense; Pedigree; Phenotype; Ryanodine Receptor Calcium Release Channel

2001
Testing for malignant hyperthermia.
    Anesthesiology, 2002, Volume: 96, Issue:1

    Topics: Anesthesia; Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensitivity and Specificity

2002
Mutation screening in the ryanodine receptor 1 gene (RYR1) in patients susceptible to malignant hyperthermia who show definite IVCT results: identification of three novel mutations.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:6

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Genetic Testing; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Mutation; Ryanodine Receptor Calcium Release Channel

2002
RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes.
    Human mutation, 2002, Volume: 20, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Exons; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle, Skeletal; Mutation; Myopathy, Central Core; Phenotype; Prevalence; Retrospective Studies; Ryanodine; Ryanodine Receptor Calcium Release Channel; United Kingdom

2002
Results of contracture tests with halothane, caffeine, and ryanodine depend on different malignant hyperthermia-associated ryanodine receptor gene mutations.
    Anesthesiology, 2002, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Child; Child, Preschool; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Mutation; Prospective Studies; Ryanodine Receptor Calcium Release Channel

2002
Reproducibility of in vitro contracture test results in patients tested for malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity

2002
"Noninvasive" testing for malignant hyperthermia susceptibility.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

2002
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Mutation; Ryanodine Receptor Calcium Release Channel

2002
Inhibitory effect of caffeine on C-fibre-evoked excitation in the rat spinal dorsal horn recorded under Ca2+-free condition: an interaction with halothane.
    Neuroscience letters, 2003, Jan-09, Volume: 336, Issue:1

    Topics: Action Potentials; Afferent Pathways; Analysis of Variance; Anesthetics, Inhalation; Animals; Caffeine; Calcium; Calcium Signaling; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Halothane; In Vitro Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord

2003
Extending the skeletal muscle viability period in the malignant hyperthermia test.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:1

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Electric Stimulation; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Temperature

2003
Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript.
    Anesthesiology, 2003, Volume: 99, Issue:2

    Topics: Amino Acid Substitution; Anesthetics, Inhalation; Caffeine; Cell Line; DNA, Complementary; Halothane; Humans; Leukocytes; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Mutation; Pedigree; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ryanodine Receptor Calcium Release Channel; Transcription, Genetic

2003
Mg2+ dependence of halothane-induced Ca2+ release from the sarcoplasmic reticulum in rat skeletal muscle.
    The Journal of physiology, 2003, Sep-01, Volume: 551, Issue:Pt 2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Cytosol; Halothane; In Vitro Techniques; Magnesium; Muscle, Skeletal; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum

2003
Calcium release from sarcoplasmic reticulum is facilitated in human myotubes derived from carriers of the ryanodine receptor type 1 mutations Ile2182Phe and Gly2375Ala.
    Genetic testing, 2003,Fall, Volume: 7, Issue:3

    Topics: Adult; Aged; Caffeine; Calcium; Child; Child, Preschool; Cresols; Female; Genetic Predisposition to Disease; Halothane; Heterozygote; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Point Mutation; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum

2003
A new mutation in the skeletal ryanodine receptor gene (RYR1) is potentially causative of malignant hyperthermia, central core disease, and severe skeletal malformation.
    American journal of medical genetics. Part A, 2004, Jan-30, Volume: 124A, Issue:3

    Topics: Adolescent; Base Sequence; Caffeine; DNA; DNA Mutational Analysis; Dysostoses; Family Health; Female; Genotype; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Musculoskeletal Abnormalities; Mutation; Myopathy, Central Core; Pedigree; Phenotype; Point Mutation; Ryanodine Receptor Calcium Release Channel

2004
Genetic testing for malignant hyperthermia in North America.
    Anesthesiology, 2004, Volume: 100, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Genetic Testing; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; North America; Ryanodine Receptor Calcium Release Channel

2004
Similar susceptibility to halothane, caffeine and ryanodine in vitro reflects pharmacogenetic variability of malignant hyperthermia.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Genetic Predisposition to Disease; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Retrospective Studies; Ryanodine; Time Factors

2004
[Delayed onset of malignant hyperthermia crisis during a living donor liver transplantation caused by sevoflurane].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2004, Volume: 39, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Halothane; Humans; Liver Transplantation; Living Donors; Male; Malignant Hyperthermia; Methyl Ethers; Sevoflurane

2004
Functional characterization of malignant hyperthermia-associated RyR1 mutations in exon 44, using the human myotube model.
    Neuromuscular disorders : NMD, 2004, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthetics; Biopsy; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Child; Child, Preschool; Cresols; Dose-Response Relationship, Drug; Exons; Family Health; Fungicides, Industrial; Fura-2; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Molecular Biology; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Ryanodine Receptor Calcium Release Channel

2004
Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:8

    Topics: Anesthetics, Inhalation; Caffeine; DNA; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Mutation; Phosphodiesterase Inhibitors; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; ROC Curve; Ryanodine

2004
Mg2+ dependence of halothane-induced Ca2+ release from the sarcoplasmic reticulum in skeletal muscle from humans susceptible to malignant hyperthermia.
    Anesthesiology, 2004, Volume: 101, Issue:6

    Topics: Anesthetics, Inhalation; Caffeine; Calcium; Central Nervous System Stimulants; Cytosol; Halothane; Humans; In Vitro Techniques; Magnesium; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Ryanodine; Sarcoplasmic Reticulum

2004
Malignant hyperthermia: update on susceptibility testing.
    JAMA, 2005, Jun-15, Volume: 293, Issue:23

    Topics: Algorithms; B-Lymphocytes; Biopsy; Caffeine; Disease Susceptibility; DNA Mutational Analysis; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Musculoskeletal Diseases; Ryanodine Receptor Calcium Release Channel

2005
Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.
    Journal of the American Veterinary Medical Association, 2005, Sep-01, Volume: 227, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Biopsy; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Female; Genes, Dominant; Halothane; Horse Diseases; Horses; Male; Muscle Contraction; Muscle, Skeletal; Pedigree; Physical Conditioning, Animal; Recurrence; Rhabdomyolysis

2005
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    Anesthesiology, 2006, Volume: 104, Issue:1

    Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Creatine Kinase; Cresols; Dose-Response Relationship, Drug; Electrolytes; Glucose; Halothane; Ketamine; Lactic Acid; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Propofol; Pyruvic Acid; Ryanodine Receptor Calcium Release Channel; Swine

2006
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Injections, Intramuscular; Lactic Acid; Malignant Hyperthermia; Microdialysis; Swine

2006
Validity and new malignant hyperthermia diagnostic procedures.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:1

    Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Reproducibility of Results; Ryanodine

2006
Pharmacologic modulation of skeletal muscle metabolism: a microdialysis study.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:4

    Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; In Vitro Techniques; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

2006
Malignant hyperthermia in China.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Anesthesia, General; Caffeine; China; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction

2006
Male preponderance of patients testing positive for malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:5

    Topics: Caffeine; Family; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Mutation; Registries; Research Design; Sex Factors; Statistics, Nonparametric; Sweden

2007
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Kinetics; Lactates; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Pyruvates; Reference Values; Ryanodine; Ryanodine Receptor Calcium Release Channel; Swine; Swine Diseases

2008
Fulminant malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:1

    Topics: Adult; Anesthetics, General; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Neuromuscular Nondepolarizing Agents; Oral Surgical Procedures; Pedigree; Vecuronium Bromide

2008
[Application of caffeine-halothane contracture test in the diagnosis of malignant hyperthermia].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2008, Volume: 30, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Creatine Kinase; Enzyme-Linked Immunosorbent Assay; Halothane; Humans; Isoflurane; Malignant Hyperthermia; Muscle, Skeletal; Myoglobin; Ryanodine Receptor Calcium Release Channel

2008
[In-vivo diagnosis of malignant hyperthermia susceptibility: a microdialysis study].
    Der Anaesthesist, 2008, Volume: 57, Issue:8

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; Dialysis Solutions; Female; Halothane; Hemodynamics; Humans; Injections, Intramuscular; Lactic Acid; Male; Malignant Hyperthermia; Microdialysis; Middle Aged; Muscle, Skeletal; Myoglobin; Psychometrics; Young Adult

2008
An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Adult; Biopsy; Caffeine; Case-Control Studies; Disease Susceptibility; Female; Halothane; Humans; Lactates; Male; Malignant Hyperthermia; Middle Aged; Muscles; Pilot Projects; Quadriceps Muscle

2008
Novel ryanodine receptor mutation that may cause malignant hyperthermia.
    Anesthesiology, 2008, Volume: 109, Issue:3

    Topics: Amino Acid Substitution; Anesthetics, Inhalation; Austria; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Child; Cresols; Dose-Response Relationship, Drug; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Patch-Clamp Techniques; Polymerase Chain Reaction; RNA, Messenger; Ryanodine Receptor Calcium Release Channel

2008
You're "hot" from pumping iron?
    Anesthesia and analgesia, 2009, Volume: 108, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; Dietary Supplements; Environment; Gene Expression; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Weight Lifting; Young Adult

2009
Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:6

    Topics: Anesthetics; Animals; Caffeine; Calcium; Calcium-Binding Proteins; Calsequestrin; Central Nervous System Stimulants; Dantrolene; Death, Sudden; Female; Halothane; Hot Temperature; Humans; Male; Malignant Hyperthermia; Mice; Mice, Knockout; Muscle Relaxants, Central; Muscle, Skeletal; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Survival Rate

2009
Genetic variation in RYR1 and malignant hyperthermia phenotypes.
    British journal of anaesthesia, 2009, Volume: 103, Issue:4

    Topics: Anesthetics, Inhalation; Caffeine; Creatine Kinase; DNA Mutational Analysis; DNA, Complementary; Female; Genetic Predisposition to Disease; Genotype; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Mutation; Phenotype; Phosphodiesterase Inhibitors; Ryanodine Receptor Calcium Release Channel; Tissue Culture Techniques

2009
Malignant hyperthermia susceptibility in a patient with mitochondrial disorder.
    Metabolic brain disease, 2009, Volume: 24, Issue:3

    Topics: Abnormalities, Multiple; Aged; Anesthesia; Anesthetics, Inhalation; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Mitochondrial Diseases; Muscle, Skeletal; Phosphodiesterase Inhibitors

2009
Intramuscular injection of malignant hyperthermia trigger agents induces hypermetabolism in susceptible and nonsusceptible individuals.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Aged; Caffeine; Carbon Dioxide; Female; Halothane; Humans; Injections, Intramuscular; Lactates; Male; Malignant Hyperthermia; Middle Aged; Muscle, Skeletal; Oxygen; Soybean Oil

2010
The role of CACNA1S in predisposition to malignant hyperthermia.
    BMC medical genetics, 2009, Oct-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Caffeine; Calcium Channels; Calcium Channels, L-Type; Child; Cohort Studies; Female; Genetic Predisposition to Disease; Halothane; Haplotypes; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Mutation; Polymorphism, Single Nucleotide; Young Adult

2009
Multigenerational Brazilian family with malignant hyperthermia and a novel mutation in the RYR1 gene.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2009, Volume: 42, Issue:12

    Topics: Brazil; Caffeine; Contracture; Family; Female; Genetic Testing; Halothane; Humans; Male; Malignant Hyperthermia; Mutation, Missense; Pedigree; Ryanodine Receptor Calcium Release Channel

2009
Contractile properties of esophageal striated muscle: comparison with cardiac and skeletal muscles in rats.
    Journal of biomedicine & biotechnology, 2010, Volume: 2010

    Topics: Animals; Caffeine; Electric Stimulation; Esophagus; Gap Junctions; Halothane; In Vitro Techniques; Male; Muscle Contraction; Muscle, Skeletal; Myocardium; Potassium; Rats; Rats, Wistar

2010
Use of the caffeine-halothane contracture test for the diagnosis of malignant hyperthermia in Brazil.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Sensitivity and Specificity; Severity of Illness Index; Young Adult

2010
Clinical features and diagnosis for Chinese cases with malignant hyperthermia: a case cluster from 2005 to 2007.
    Chinese medical journal, 2010, May-20, Volume: 123, Issue:10

    Topics: Adolescent; Adult; Caffeine; Child; China; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Muscle Contraction; Young Adult

2010
Analysis of human cultured myotubes responses mediated by ryanodine receptor 1.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Caffeine; Calcium; Cells, Cultured; Child; Child, Preschool; Cresols; Dose-Response Relationship, Drug; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Fibers, Skeletal; ROC Curve; Ryanodine Receptor Calcium Release Channel; Young Adult

2011
Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study.
    Minerva anestesiologica, 2011, Volume: 77, Issue:8

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Methyl Ethers; Muscle Contraction; Respiratory Muscles; Sevoflurane

2011
Novel double and single ryanodine receptor 1 variants in two Austrian malignant hyperthermia families.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:5

    Topics: Amino Acid Substitution; Anesthesia, General; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Child; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Genetic Variation; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Pedigree; Polymerase Chain Reaction; Ryanodine Receptor Calcium Release Channel; Tonsillectomy

2012
3,5-Di-t-butyl catechol is a potent human ryanodine receptor 1 activator, not suitable for the diagnosis of malignant hyperthermia susceptibility.
    Pharmacological research, 2012, Volume: 66, Issue:1

    Topics: Caffeine; Calcium; Calcium Channel Agonists; Catechols; Cells, Cultured; Dose-Response Relationship, Drug; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Predictive Value of Tests; Risk Assessment; Risk Factors; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors

2012
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene.
    Anaesthesia, 2012, Volume: 67, Issue:9

    Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatine Kinase; Dantrolene; Disseminated Intravascular Coagulation; Female; Genetic Variation; Hallucinogens; Haloperidol; Halothane; Humans; Multiple Organ Failure; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Recurrence; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Spectrum Analysis; Young Adult

2012
A family with discordance between malignant hyperthermia susceptibility and rippling muscle disease.
    Journal of anesthesia, 2013, Volume: 27, Issue:1

    Topics: Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Caffeine; Caveolin 3; Creatine Kinase; Family; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscular Diseases; Mutation; Pedigree; Phenotype; Phosphodiesterase Inhibitors; Treatment Outcome

2013
In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:8

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Membrane Potentials; Mice; Mice, Neurologic Mutants; Muscle Contraction; Muscle, Skeletal; Myotonia Congenita; Ryanodine Receptor Calcium Release Channel

2013
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female; Fever; Halothane; Humans; Hypercapnia; Incidence; Infant; Male; Malignant Hyperthermia; Middle Aged; Mutation; Registries; Retrospective Studies; Ryanodine Receptor Calcium Release Channel; Succinylcholine; Tachycardia; Young Adult

2014
Analysis of histomorphology in malignant hyperthermia-susceptible patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:10

    Topics: Adult; Caffeine; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Mutation; Phenotype; Retrospective Studies

2013
Contractile elements in muscular fascial tissue - implications for in-vitro contracture testing for malignant hyperthermia.
    Anaesthesia, 2014, Volume: 69, Issue:9

    Topics: Anesthesia, General; Anesthetics, General; Animals; Biopsy; Caffeine; Central Nervous System Stimulants; Electric Stimulation; Facial Muscles; Fluorescent Antibody Technique; Halothane; Histamine H1 Antagonists; Immunohistochemistry; In Vitro Techniques; Malignant Hyperthermia; Mice; Mice, Inbred BALB C; Muscle Contraction; Pyrilamine; Rats; Rats, Wistar

2014
Malignant hyperthermia testing in probands without adverse anesthetic reaction.
    Anesthesiology, 2015, Volume: 123, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects and Adverse Reactions; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Retrospective Studies; Young Adult

2015
Is there a link between exertional heat stroke and susceptibility to malignant hyperthermia?
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; Heat Stroke; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Retrospective Studies; Risk Factors

2015
Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.
    Clinical science (London, England : 1979), 2016, Volume: 130, Issue:1

    Topics: Biopsy; Caffeine; Case-Control Studies; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Gasotransmitters; Gene Expression Regulation, Enzymologic; Glyburide; Halothane; Humans; Hydrogen Sulfide; In Vitro Techniques; KATP Channels; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Potassium Channel Blockers; RNA, Messenger; Signal Transduction; Sulfides; Up-Regulation

2016
Functional characterization of the RYR1 mutation p.Arg4737Trp associated with susceptibility to malignant hyperthermia.
    Neuromuscular disorders : NMD, 2016, Volume: 26, Issue:1

    Topics: Anesthetics; Arginine; B-Lymphocytes; Caffeine; Cell Line, Transformed; Cresols; Family Health; Female; Fungicides, Industrial; Genetic Predisposition to Disease; Germany; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Phosphodiesterase Inhibitors; Polymorphism, Single Nucleotide; Ryanodine Receptor Calcium Release Channel; Tryptophan

2016
Skeletal Muscle Metabolic Dysfunction in Patients With Malignant Hyperthermia Susceptibility.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: Adult; Anesthetics; Anthropometry; Caffeine; Case-Control Studies; Disease Susceptibility; Exercise Test; Female; Halothane; Humans; Magnetic Resonance Imaging; Male; Malignant Hyperthermia; Metabolic Diseases; Middle Aged; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Oxygen; Surveys and Questionnaires

2017
Microdialysis and ultrasound elastography for monitoring of localized muscular reaction after pharmacological stimulation in rats.
    BMC research notes, 2018, Sep-03, Volume: 11, Issue:1

    Topics: Animals; Caffeine; Elasticity Imaging Techniques; Halothane; Malignant Hyperthermia; Microdialysis; Muscle Contraction; Muscle, Skeletal; Rats

2018
Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia-susceptible Pigs.
    Anesthesiology, 2018, Volume: 129, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Elasticity Imaging Techniques; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Pilot Projects; Swine

2018
Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1.
    British journal of anaesthesia, 2018, Volume: 121, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Gene Knock-In Techniques; Halothane; Heat Stress Disorders; Male; Malignant Hyperthermia; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Phenotype; Potassium Chloride; Ryanodine Receptor Calcium Release Channel

2018
Abnormal calcium signalling and the caffeine-halothane contracture test.
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Signal Transduction

2019
Understanding malignant hyperthermia: each move forward opens our eyes to the distance left to travel.
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Caffeine; Calcium; Contracture; Halothane; Humans; Malignant Hyperthermia

2019
A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility.
    British journal of anaesthesia, 2020, Volume: 125, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Female; Genotype; Halothane; Humans; Malignant Hyperthermia; Mutation; Phenotype; Reproducibility of Results; Ryanodine Receptor Calcium Release Channel

2020
Malignant Hyperthermia: A Killer If Ignored.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2022, Volume: 37, Issue:4

    Topics: Adolescent; Caffeine; China; Halothane; Humans; Malignant Hyperthermia; Mutation

2022
Management of patients susceptible to malignant hyperthermia: A surgeon's perspective.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 159

    Topics: Caffeine; Child; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Retrospective Studies; Surgeons

2022
Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia.
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal

2023
What is malignant hyperthermia susceptibility?
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Anesthesia; Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia

2023