halothane has been researched along with 2-chloro-1,1-difluoroethylene in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baden, JM; Edmunds, HN; Simmon, VF | 1 |
| Cohen, EN; Sharp, JH; Trudell, JR | 1 |
| Baker, MT; Bates, JN; Leff, SV | 1 |
| Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC | 1 |
| Kawata, S; Sugiyama, T; Tamura, S; Tarui, S | 1 |
| Fujii, K; Kikuchi, H; Okida, M | 1 |
| Cousins, MJ; Plummer, JL; Van der Walt, JH | 1 |
| Baker, MT; Van Dyke, RA | 1 |
| Cohen, EN; Sachdev, K; Simmon, VF | 1 |
| Ahr, HJ; King, LJ; Nastainczyk, W; Ullrich, V | 1 |
| Brown, BR; Gandolfi, AJ; Lind, RC; Maiorino, RM; Sipes, IG | 1 |
| Adams, JF; Cousins, MJ; Gourlay, GK; Hall, P | 1 |
| Adams, JF; Cousins, MJ; Gourlay, GK; Sharp, JH | 1 |
| Fujii, K | 1 |
14 other study(ies) available for halothane and 2-chloro-1,1-difluoroethylene
| Article | Year |
|---|---|
Mutagenicity studies with volatile metabolites of halothane.
Topics: Biological Assay; Biotransformation; Cells, Cultured; Chlorofluorocarbons; Ethylenes; Halothane; Hydrocarbons, Halogenated; Mutagens; Neoplasms; Salmonella typhimurium | 1979 |
Volatile metabolites and decomposition products of halothane in man.
Topics: Anesthesia, Inhalation; Biotransformation; Chlorofluorocarbons; Chromatography, Gas; Ethylenes; Halothane; Humans; Hydrocarbons, Halogenated; Mass Spectrometry; Volatilization | 1979 |
Stimulatory effects of halothane and isoflurane on fluoride release and cytochrome P-450 loss caused by metabolism of 2-chloro-1,1-difluoroethene, a halothane metabolite.
Topics: Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethers; Fluorides; Halothane; Hydrocarbons, Halogenated; Isoflurane; Male; Microsomes, Liver; Oxygen; Rats; Rats, Inbred Strains | 1987 |
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Halothane; Hydrocarbons, Halogenated; Hyperthyroidism; Liver Diseases; Male; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Trifluoroacetic Acid; Triiodothyronine | 1988 |
Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liver.
Topics: Anaerobiosis; Animals; Chlorofluorocarbons; Cytochrome b Group; Cytochromes b5; Electron Transport; Halothane; Hydrocarbons, Halogenated; Male; Malonates; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1987 |
Concentration-dependence of halothane metabolism in rabbits.
Topics: Animals; Bile; Chlorofluorocarbons; Ethane; Halothane; Male; Oxidation-Reduction; Rabbits; Trifluoroacetic Acid | 1986 |
Reductive metabolism of halothane in children.
Topics: Anesthesia, Inhalation; Child; Child, Preschool; Chlorofluorocarbons; Female; Halothane; Humans; Hydrocarbons, Halogenated; Male; Oxidation-Reduction; Time Factors | 1984 |
Reductive halothane metabolite formation and halothane binding in rat hepatic microsomes.
Topics: Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Dithionite; Enflurane; Halothane; Hydrocarbons, Halogenated; Isoflurane; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1984 |
Genotoxic and mutagenic assays of halothane metabolites in Bacillus subtilis and Salmonella typhimurium.
Topics: Animals; Bacillus subtilis; Chlorofluorocarbons; DNA; Dose-Response Relationship, Drug; Ethylenes; Genes; Halothane; Hydrocarbons, Halogenated; Male; Mutagens; Rats; Salmonella typhimurium | 1980 |
The mechanism of reductive dehalogenation of halothane by liver cytochrome P450.
Topics: Animals; Biotransformation; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Halothane; Hydrocarbons, Halogenated; In Vitro Techniques; Liver; Male; Models, Chemical; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1982 |
Factors affecting the formation of chlorotrifluoroethane and chlorodifluoroethylene from halothane.
Topics: Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Ethylenes; Halothane; Hydrocarbons, Halogenated; In Vitro Techniques; Male; Microsomes, Liver; Rats | 1981 |
Genetic differences in reductive metabolism and hepatotoxicity of halothane in three rat strains.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Enzyme Induction; Ethylenes; Genetic Variation; Halothane; Hydrocarbons, Halogenated; Hypoxia; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
Time-course of formation of volatile reductive metabolites of halothane in humans and an animal model.
Topics: Adult; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Disease Models, Animal; Enzyme Induction; Ethylenes; Female; Halothane; Humans; Hydrocarbons, Halogenated; Kinetics; Male; Middle Aged; Phenobarbital; Rats; Rats, Inbred F344 | 1980 |
Isoflurane acts as an inhibitor of oxidative dehalogenation while acting as an accelerator of reductive dehalogenation of halothane in guinea pig liver microsomes.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Guinea Pigs; Halothane; Isoflurane; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Spectrophotometry, Ultraviolet; Trifluoroacetic Acid | 1995 |