Compounds > haloperidol

haloperidol and troleandomycin

haloperidol has been researched along with troleandomycin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Kudo, S; Odomi, M1
Kobayashi, S; Kumai, T; Tanaka, M; Tateishi, T; Watanabe, M1
Kobayashi, S; Kumai, T; Moriya, H; Satoh, T; Tanaka, M; Tateishi, T; Watanabe, M; Yamaguchi, S1

Other Studies

5 other study(ies) available for haloperidol and troleandomycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:3

    Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antiparkinson Agents; Biotransformation; Biperiden; Carteolol; Cell Line, Transformed; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Haloperidol; Humans; Hydroxylation; Isoenzymes; Kinetics; Microsomes; Mixed Function Oxygenases; Oxidation-Reduction; Quinidine; Sparteine; Troleandomycin

1998
Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Erythromycin; Half-Life; Haloperidol; Immune Sera; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Propionates; Quinine; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Theophylline; Troleandomycin

1999
CYP3A is responsible for N-dealkylation of haloperidol and bromperidol and oxidation of their reduced forms by human liver microsomes.
    Life sciences, 2000, Nov-03, Volume: 67, Issue:24

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Haloperidol; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Propionates; Troleandomycin

2000