haloperidol and trazodone

haloperidol has been researched along with trazodone in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19907 (18.42)18.7374
1990's3 (7.89)18.2507
2000's15 (39.47)29.6817
2010's12 (31.58)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Beaumont, K; Di, L; Maurer, TS; Smith, DA1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A1
Baldini, A; Ciottoli, GB; Lisciani, R1
Klieser, E; Lehmann, E1
Barclay, AM1
Dahms, JL; Seiden, LS; Shaughnessy, RA1
Schachter, D; Schibuk, M1
Karelson, EI; Tarve, US; Tiakhepyl'd, LIa1
Lauterbach, EC1
Ishida, M; Kaneko, S; Mihara, K; Ohkubo, T; Osanai, T; Otani, K; Sugawara, K; Suzuki, A; Yasui, N1
Berisford, MA; Gray, KF; Gunay, I; Mahler, ME; Sultzer, DL1
Auchus, AP; Foster, NL; Grundman, M; Logsdon, RG; Mellow, AM; Peskind, E; Raskind, M; Sano, M; Schafer, K; Schneider, LS; Tariot, P; Teri, L; Thal, LJ; Thomas, RG; Tractenberg, RE; Weiner, MF; Whitehouse, P1
Nobili, L; Rizzo, P; Saccomani, L1
Gray, KF; Gunay, I; Mahler, ME; Sultzer, DL; Wheatley, MV1
Garrido Barral, A; González Moneo, MJ1
Galasko, D; Gamst, A; Logsdon, R; Sano, M; Teri, L; Thal, LJ; Thomas, R; Tractenberg, RE; Weiner, MF1
Cummings, JL; Gamst, A; Masterman, D; Teri, L; Thal, LJ; Tractenberg, RE1
Irvin, W; Kim, WY; MacDonald, G; Smith, JK1
Dunbar, M; Freter, S; Koller, K; MacKnight, C; Rockwood, K1

Reviews

2 review(s) available for haloperidol and trazodone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Latest therapies for treating dementia].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Cognition; Cohort Studies; Controlled Clinical Trials as Topic; Dementia, Vascular; Donepezil; Female; Fluoxetine; Galantamine; Haloperidol; Hormone Replacement Therapy; Humans; Hydroxychloroquine; Indans; Middle Aged; Nootropic Agents; Piperidines; Placebos; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Trazodone

2002

Trials

8 trial(s) available for haloperidol and trazodone

ArticleYear
Experimental examination of trazodone.
    Clinical neuropharmacology, 1989, Volume: 12 Suppl 1

    Topics: Adult; Amitriptyline; Anxiety; Depression; Depressive Disorder; Double-Blind Method; Female; Haloperidol; Humans; Male; Random Allocation; Schizophrenia; Trazodone

1989
Increases in plasma concentration of m-chlorophenylpiperazine, but not trazodone, with low-dose haloperidol.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Cytochrome P-450 CYP2D6 Inhibitors; Depressive Disorder; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Piperazines; Trazodone

1997
A double-blind comparison of trazodone and haloperidol for treatment of agitation in patients with dementia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1997,Winter, Volume: 5, Issue:1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Dementia; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Neuropsychological Tests; Psychomotor Agitation; Trazodone; Treatment Outcome

1997
Treatment of agitation in AD: a randomized, placebo-controlled clinical trial.
    Neurology, 2000, Nov-14, Volume: 55, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Behavior Therapy; Double-Blind Method; Female; Haloperidol; Humans; Male; Psychomotor Agitation; Trazodone

2000
Combined treatment with haloperidol and trazodone in patients with tic disorders.
    Journal of child and adolescent psychopharmacology, 2000,Winter, Volume: 10, Issue:4

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Child; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Tic Disorders; Trazodone

2000
Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia?
    Journal of the American Geriatrics Society, 2001, Volume: 49, Issue:10

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Double-Blind Method; Female; Haloperidol; Humans; Male; Mood Disorders; Psychotic Disorders; Statistics, Nonparametric; Trazodone; Treatment Outcome

2001
No long-term effect of behavioral treatment on psychotropic drug use for agitation in Alzheimer's disease patients.
    Journal of geriatric psychiatry and neurology, 2002,Summer, Volume: 15, Issue:2

    Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antipsychotic Agents; Behavior Therapy; Caregivers; Female; Follow-Up Studies; Haloperidol; Humans; Interviews as Topic; Male; Psychiatric Status Rating Scales; Psychomotor Agitation; Psychotropic Drugs; Time Factors; Trazodone

2002
Translating Delirium Prevention Strategies for Elderly Adults with Hip Fracture into Routine Clinical Care: A Pragmatic Clinical Trial.
    Journal of the American Geriatrics Society, 2017, Volume: 65, Issue:3

    Topics: Aged; Aged, 80 and over; Analgesics; Anti-Dyskinesia Agents; Dehydration; Delirium; Female; Haloperidol; Hip Fractures; Humans; Laxatives; Length of Stay; Male; Orthopedic Nursing; Postoperative Care; Postoperative Complications; Selective Serotonin Reuptake Inhibitors; Trazodone; Urinary Catheterization

2017

Other Studies

28 other study(ies) available for haloperidol and trazodone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Volume of Distribution in Drug Design.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Drug Design; Half-Life; Pharmacokinetics

2015
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
    Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49

    Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines

2021
Behavioral study on the interactions between trazodone and L-dopa.
    Pharmacological research communications, 1979, Volume: 11, Issue:3

    Topics: Animals; Behavior, Animal; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Muscle Rigidity; Piperazines; Time Factors; Trazodone

1979
Psychotropic drugs in the elderly. Selection of the appropriate agent.
    Postgraduate medicine, 1985, Volume: 77, Issue:8

    Topics: Age Factors; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Chlordiazepoxide; Cimetidine; Diazepam; Flurazepam; Haloperidol; Humans; Kinetics; Lithium; Phenothiazines; Physostigmine; Psychotropic Drugs; Thiothixene; Trazodone

1985
Behavioral screen for antidepressants: the effects of drugs and electroconvulsive shock on performance under a differential-reinforcement-of-low-rate schedule.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: Animals; Antidepressive Agents; Bupropion; Clozapine; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Haloperidol; Male; Propiophenones; Rats; Rats, Inbred Strains; Reinforcement Schedule; Trazodone; Zimeldine

1985
A role for catecholamines in the pathogenesis of neuroleptic malignant syndrome.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:1

    Topics: Akathisia, Drug-Induced; Brain Chemistry; Catecholamines; Chlorpromazine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Neuroleptic Malignant Syndrome; Receptors, Dopamine; Trazodone

1986
[Effect of psychotropic drugs on cerebral Ca-activated ATPase in vitro].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:5

    Topics: Amphetamine; Animals; Benactyzine; Brain; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Chlorpromazine; Guinea Pigs; Haloperidol; Imipramine; In Vitro Techniques; Perphenazine; Psychotropic Drugs; Trazodone

1981
Reversible intermittent rhythmic myoclonus with fluoxetine in presumed Pick's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:3

    Topics: Affective Disorders, Psychotic; Brain; Dementia; Dose-Response Relationship, Drug; Electroencephalography; Fluoxetine; Haloperidol; Humans; Male; Middle Aged; Myoclonus; Serotonin; Trazodone

1994
Regression to the mean: implications for clinical trials of psychotropic agents in dementia.
    Current Alzheimer research, 2004, Volume: 1, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Behavior Therapy; Data Interpretation, Statistical; Female; Haloperidol; Humans; Male; Psychomotor Agitation; Psychotropic Drugs; Randomized Controlled Trials as Topic; Regression Analysis; Research Design; Time Factors; Trazodone; Treatment Outcome

2004
Dexamethasone-induced posterior reversible encephalopathy syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jun-10, Volume: 25, Issue:17

    Topics: Anti-Inflammatory Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Dopamine Antagonists; Female; Fractures, Bone; Haloperidol; Humans; Hypertensive Encephalopathy; Hypnotics and Sedatives; Inflammation; Lung Neoplasms; Middle Aged; Pyridines; Selective Serotonin Reuptake Inhibitors; Tomography, X-Ray Computed; Trazodone; Zolpidem

2007