haloperidol and selegiline

haloperidol has been researched along with selegiline in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's4 (12.50)18.2507
2000's15 (46.88)29.6817
2010's6 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cohen, G1
Cohen, G; Spina, MB1
Defazio, G; Ferrari, E; Lamberti, P; Lepore, V; Livrea, P1
Kaakkola, S; Männistö, PT; Nuutila, J1
Anderson, B; Severson, JA1
Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P1
Knoll, B; Knoll, J; Timar, J1
Flórez, J; Mediavilla, A; Pazos, A1
Cadet, JL; Gewirtz, GR; Gorman, JM; Sarti, P; Sharif, Z1
Baudewig, J; Bruns, D; Paulus, W; Tergau, F; Ziemann, U1
Wu, WR; Zhu, XZ1
Alper, RH; Gilliland, SL; Levant, B1
Marsh, C; Preskorn, SH; Shad, MU1
Arya, P; Butler, R; Warner, J1
Preskorn, SH1
Gomita, Y; Kawasaki, H; Kimoto, S; Kitagawa, K; Kitamura, Y; Sagara, H; Sendo, T; Shibata, K1
Ali, J; Baboota, S; Dang, S; Kumar, S; Nigam, K1

Reviews

2 review(s) available for haloperidol and selegiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Dementia.
    Clinical evidence, 2004, Issue:11

    Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Donepezil; Galantamine; Ginkgo biloba; Haloperidol; Humans; Indans; Memantine; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Risperidone; Rivastigmine; Selegiline; Tacrine; Vitamin E

2004

Trials

1 trial(s) available for haloperidol and selegiline

ArticleYear
Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs.
    Electroencephalography and clinical neurophysiology, 1997, Volume: 105, Issue:6

    Topics: Administration, Oral; Adult; Analysis of Variance; Bromocriptine; Dopamine Agonists; Dopamine Antagonists; Electromyography; Evoked Potentials, Motor; Female; Haloperidol; Humans; Levodopa; Magnetics; Male; Motor Cortex; Physical Stimulation; Reference Values; Selegiline; Sulpiride

1997

Other Studies

29 other study(ies) available for haloperidol and selegiline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Monoamine oxidase and oxidative stress at dopaminergic synapses.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Animals; Clorgyline; Corpus Striatum; Dopamine; Glutathione; Glutathione Reductase; Haloperidol; In Vitro Techniques; Levodopa; Male; Mice; Monoamine Oxidase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stress, Physiological; Substantia Nigra; Synapses; Synaptosomes

1990
Deprenyl suppresses the oxidant stress associated with increased dopamine turnover.
    Annals of neurology, 1989, Volume: 26, Issue:5

    Topics: Animals; Corpus Striatum; Dopamine; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Haloperidol; Male; Mice; Monoamine Oxidase; Oxidation-Reduction; Phenethylamines; Selegiline

1989
Facial dystonia: clinical features, prognosis and pharmacology in 31 patients.
    Italian journal of neurological sciences, 1989, Volume: 10, Issue:6

    Topics: Adult; Aged; Basal Ganglia Diseases; Botulinum Toxins; Drug Combinations; Female; Haloperidol; Humans; Levodopa; Male; Meige Syndrome; Middle Aged; Phenethylamines; Prognosis; Selegiline

1989
Potentiation of central effects of L-dopa by an inhibitor of catechol-O-methyltransferase.
    Journal of neural transmission, 1987, Volume: 70, Issue:3-4

    Topics: Animals; Behavior, Animal; Catalepsy; Catechol O-Methyltransferase Inhibitors; Central Nervous System; Haloperidol; Levodopa; Male; Motor Activity; Phenethylamines; Propiophenones; Rats; Selegiline; Specific Pathogen-Free Organisms

1987
Chronic antidepressant treatment and mouse brain 3H-imipramine binding.
    Journal of neuroscience research, 1986, Volume: 16, Issue:2

    Topics: Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Desipramine; Haloperidol; Imipramine; Male; Mice; Mice, Inbred C57BL; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Selegiline

1986
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior

1987
Long-term administration of (-)deprenyl (selegiline), a compound which facilitates dopaminergic tone in the brain, leaves the sensitivity of dopamine receptors to apomorphine unchanged.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2

    Topics: Animals; Apomorphine; Clorgyline; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Imipramine; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Selegiline; Stereotyped Behavior

1986
Cardiovascular effects of intracerebroventricular injection of dopamine after selective MAO inhibition in rats.
    Neuropharmacology, 1982, Volume: 21, Issue:4

    Topics: Animals; Blood Pressure; Clorgyline; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Heart Rate; Injections, Intravenous; Male; Monoamine Oxidase Inhibitors; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Selegiline

1982
Selegiline for neuroleptic-induced parkinsonism.
    Pharmacopsychiatry, 1993, Volume: 26, Issue:4

    Topics: Antipsychotic Agents; Haloperidol; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Schizophrenia; Selegiline

1993
The amphetamine-like reinforcing effect and mechanism of L-deprenyl on conditioned place preference in mice.
    European journal of pharmacology, 1999, Jan-01, Volume: 364, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Reinforcement, Psychology; Selegiline

1999
Pharmacology of quinpirole-stimulated [35S]GTPgammaS binding: discrepancy with receptor binding profile.
    European journal of pharmacology, 2000, Mar-31, Volume: 392, Issue:3

    Topics: Animals; Benzazepines; Binding, Competitive; Clorgyline; Clozapine; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Male; Membranes; Monoamine Oxidase Inhibitors; Quinpirole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Selegiline; Spiperone; Sulfur Radioisotopes; Thiazoles

2000
The economic consequences of a drug-drug interaction.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:1

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Depression; Drug Interactions; Female; Fluoxetine; Haloperidol; Health Care Costs; Humans; Olanzapine; Parkinson Disease; Pirenzepine; Selegiline; Trihexyphenidyl

2001
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:1

    Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin; Dementia; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Fluoxetine; Haloperidol; Hospitalization; Humans; Hypnotics and Sedatives; Lorazepam; Parkinson Disease; Psychomotor Agitation; Selegiline; Trihexyphenidyl

2008
Selegilin exerts antidepressant-like effects during the forced swim test in adrenocorticotropic hormone-treated rats.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzazepines; Cosyntropin; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Models, Animal; Monoamine Oxidase Inhibitors; Motor Activity; Naphthalenes; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D3; Selegiline; Swimming; Time Factors

2008
Selegiline Nanoformulation in Attenuation of Oxidative Stress and Upregulation of Dopamine in the Brain for the Treatment of Parkinson's Disease.
    Rejuvenation research, 2018, Volume: 21, Issue:5

    Topics: Animals; Antioxidants; Antiparkinson Agents; Brain; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Compounding; Haloperidol; Male; Nanoparticles; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Selegiline; Up-Regulation

2018