haloperidol has been researched along with remoxipride in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (7.69) | 18.7374 |
| 1990's | 55 (70.51) | 18.2507 |
| 2000's | 12 (15.38) | 29.6817 |
| 2010's | 5 (6.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angeby-Möller, K; de Paulis, T; Hall, H; Johansson, L; Kumar, Y; Ogren, SO; Rämsby, S; Sällemark, M | 1 |
| Angeby-Möller, K; de Paulis, T; Florvall, L; Hall, H; Johansson, L; Kumar, Y; Ogren, SO; Rämsby, S | 1 |
| Carlsson, A; Hansson, L; Lin, CH; Smith, MW; Sonesson, C; Svensson, K; Waters, N; Wikström, H | 1 |
| Chen, X; Huston, K; Meade, R; Ross, PC; Thurkauf, A; Wasley, JW; Woodruff, KH; Yuan, J | 1 |
| Anglada, L; Bolós, J; Burgarolas, C; Castelló, JM; Gubert, S; Ortiz, JA; Planas, JM; Sacristán, A | 1 |
| Asmakova, LS; Bondarenko, NA; Briling, VK; Gudasheva, TA; Ostrovskaya, RU; Rozantsev, GG; Seredenin, SB; Voronina, TA; Zaitseva, NI | 1 |
| Bacolod, MD; Brodbeck, R; Craven, K; Girard, B; Hodgetts, K; Hoffman, D; Kieltyka, A; Rachwal, S; Thurkauf, A; Tran, J; Wasley, JW; Zhang, X; Zhao, H | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Arhem, P; Elinder, F; Ericsson, G; Sandell, L; Westlind-Danielsson, A | 1 |
| Ericson, H; Ross, SB | 1 |
| Ancill, R; Awad, G; Bakish, D; Beaudry, P; Bloom, D; Chandrasena, R; Das, M; Durand, C; Elliott, D; Lapierre, YD | 1 |
| Bryske, B; Karlsson-Boethius, G; Köhler, C; Radesäter, AC; Widman, M | 1 |
| Bissette, G; Levant, B; Nemeroff, CB; Widerlöv, E | 1 |
| Amman, J; Beckmann, H; Bunse, J; Eikmeier, G; Geretsegger, C; Hebenstreit, GF; Kanitz, RD; Kanzow, WT; Laux, G; Schubert, H | 1 |
| Brent, PJ | 1 |
| Appelberg, B; Katila, H; Kuoppasalmi, K; Lahdelma, RL; Rimón, R | 1 |
| Casey, DE; Gerlach, J | 1 |
| den Boer, JA; Westenberg, HG | 1 |
| Den Boer, JA; Huisman, J; Ohrvik, J; Ravelli, DP; Verhoeven, WM; Westenberg, HG | 2 |
| Andersen, J; Birket-Smith, M; Fensbo, C; Fogh, M; Hansen, NR; Kristensen, M; Kørner, A; Møller-Nielsen, EM; Ostergaard, P; Thiesen, S | 1 |
| Chanas, A; Deo, R; Edwards, JG; Levine, S; Mitchell, M; Plant, I; Rastogi, SC; Soni, S | 1 |
| Beckmann, H; Bunse, J; Dittmann, V; Klieser, E; König, P; Laux, G; Schöny, HW; Schröder, HG; Schubert, H; Unterweger, B | 1 |
| Akselson, S; Andersen, T; Arthur, H; Kristjansson, E; Lindgren, S; Lindström, LH; Naimell, L; Norman, O; Struwe, G; Wieselgren, IM | 1 |
| Cosyns, P; de Bleeker, E; Deleu, G; Lotstra, F; Masson, A; Mendlewicz, J; Mertens, C; Parent, M; Peuskens, J; Suy, E | 1 |
| Bartels, M; Bauer, H; Bunse, J; Gallhofer, B; Haas, S; Kanzow, WT; Klieser, E; Küfferle, B; Pflug, B; Stein, D | 1 |
| Holm, AC; Wålinder, J | 1 |
| Englund, A; Lawrie, V; Lewander, T; Morrison, D; Schlachet, A; Westerbergh, SE | 1 |
| Jostell, KG; Lapierre, YD | 1 |
| Klieser, E; Strauss, WH | 1 |
| Awad, AG; Bakish, D; Chouinard, G; Jones, B; Lapierre, YD; Manchanda, R; Max, P; McClure, DJ; Nair, NP; Saxena, B | 1 |
| Agussol, P; Alby, JM; Brion, S; Burnat, G; Castelnau, D; Deluermoz, S; Dufour, H; Ferreri, M; Goudemand, M; Patris, M | 1 |
| Lewander, T; Morrison, D; Westerbergh, SE | 1 |
| Ahlfors, UG; Appelberg, B; Hagert, U; Harma, P; Katila, H; Mahlanen, A; Mehtonen, OP; Naukkarinen, H; Outakoski, J; Rimön, R | 1 |
| Ahlenius, S; Ericson, E | 1 |
| Anderer, P; Grünberger, J; Küfferle, B; Saletu, B; Steinberger, K | 1 |
| Awad, AG; Jostell, KG; Lapierre, YD | 1 |
| Classen, W; Laux, G | 1 |
| Fowler, CJ; Magnusson, O; Mohringe, B; Ogren, SO; Wijkström, A | 1 |
| Fowler, CJ; Magnusson, O; Mohringe, B | 1 |
| Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO | 1 |
| Perrault, G; Sanger, DJ | 1 |
| Gallhofer, B; Rammsayer, T | 1 |
| Jackson, DM; Johansson, C; Svensson, L | 1 |
| Andersson, I; Gustafsson, K; Westlind-Danielsson, A | 1 |
| Goldstein, M; Ogren, SO | 1 |
| Morimoto, Y; Morio, Y; Tanimoto, H; Yakushiji, T | 1 |
| Fuxe, K; Ogren, SO; Rosén, L | 1 |
| Conley, R; Nguyen, JA; Tamminga, CA | 1 |
| Klieser, E; Lemmer, W; Strauss, WH | 1 |
| Ahlenius, S; Ericson, E; Wijkström, A | 1 |
| Lundström, J; Nilsson, LB; Ogren, SO | 1 |
| Goldman-Rakic, PS; Lidow, MS | 1 |
| Lundström, J; Nilsson, LB; Ogren, SO; Widman, M | 1 |
| Rammsayer, TH | 2 |
| Liu, KL; Lung, FW | 1 |
| Bell, R; King, DJ; Trimble, KM | 1 |
| Angus, C; Awad, AG; Lapierre, YD; Rylander, A | 1 |
| Collins, SP; Mendes, LS | 1 |
| Denning, CE; Files, FJ; Samson, HH | 1 |
| Depoortere, R; Perrault, G; Sanger, DJ | 1 |
| Angus, C; Awad, AG; Busse, E; Carle, R; Claesson, L; Denis, JF; Gauthier, B; Grafford, K; Jones, B; Labelle, A; Lapierre, YD; Lavallee, YJ; Malla, AK; Manchanda, R; Oyewumi, LK; Saxena, BM; Teehan, MD; Vincent, P; Williamson, P; Wolf, MA | 1 |
| Hillefors, M; von Euler, G | 1 |
| Philibin, SD; Porter, JH; Vann, RE; Varvel, SA; Wise, LE | 1 |
| Ashe, P; Chlan-Fourney, J; Juorio, AV; Li, XM; Nylen, K | 1 |
| Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M | 1 |
| Bruins Slot, LA; Kleven, MS; Newman-Tancredi, A | 1 |
| Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S | 1 |
| Auclair, AL; Barret-Grévoz, C; Barreto, M; Depoortère, R; Kleven, MS; Newman-Tancredi, A | 1 |
29 trial(s) available for haloperidol and remoxipride
| Article | Year |
|---|---|
A dose-finding study with remoxipride in the acute treatment of schizophrenic patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Haloperidol; Humans; Psychiatric Status Rating Scales; Recurrence; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1992 |
A double-blind comparative multicentre study of controlled-release remoxipride, immediate-release remoxipride and haloperidol in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Delayed-Action Preparations; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia | 1991 |
Plasma concentrations of remoxipride and haloperidol in relation to prolactin and short-term therapeutic outcome in schizophrenic patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Prolactin; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1991 |
Atypical neuroleptics in acute schizophrenia: a double-blind comparative study of remoxipride and haloperidol.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remoxipride; Schizophrenia | 1990 |
Double blind comparative study of remoxipride and haloperidol in acute schizophrenic patients.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Delayed-Action Preparations; Double-Blind Method; Female; Haloperidol; Homovanillic Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prolactin; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double blind comparative multicentre study of remoxipride and haloperidol in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind comparative study of remoxipride and haloperidol in acute schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Remoxipride and haloperidol in the acute phase of schizophrenia: a double-blind comparison.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Psychometrics; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind multicentre study comparing remoxipride, two and three times daily, with haloperidol in schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind comparative multicentre study of remoxipride and haloperidol in schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind comparative study of remoxipride and haloperidol in schizophrenic and schizophreniform disorders.
Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind multicentre study comparing remoxipride, controlled release formulation, with haloperidol in schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Experiences of long-term treatment with remoxipride: efficacy and tolerability.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Chronic Disease; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Long-Term Care; Male; Middle Aged; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Safety evaluation in both short- and long-term treatment of schizophrenia with remoxipride.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Overdose; Female; Haloperidol; Hemodynamics; Humans; Long-Term Care; Male; Prolactin; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Plasma concentration of remoxipride in relation to antipsychotic effect and adverse symptoms. The Canadian Remoxipride Study Group.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Cognitive disturbances in neuroleptic therapy.
Topics: Adult; Antipsychotic Agents; Benzamides; Cognition Disorders; Double-Blind Method; Haloperidol; Humans; Intelligence; Neuropsychological Tests; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders | 1990 |
A controlled dose-ranging study of remoxipride and haloperidol in schizophrenia--a Canadian multicentre trial.
Topics: Acute Disease; Adolescent; Adult; Antipsychotic Agents; Benzamides; Canada; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
A double-blind multicentre comparison of remoxipride, at two dose levels, and haloperidol.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Clinical profile of remoxipride--a combined analysis of a comparative double-blind multicentre trial programme.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Remoxipride and haloperidol in schizophrenia: a double-blind multicentre study.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Selective dopamine D2 antagonist and prolactin response in acute schizophrenia--results from remoxipride studies. The Canadian Remoxipride Study Group.
Topics: Adult; Benzamides; Double-Blind Method; Female; Haloperidol; Humans; Male; Prolactin; Receptors, Dopamine; Receptors, Dopamine D2; Remoxipride; Schizophrenia | 1990 |
Comparison of sensorimotor and cognitive performance of acute schizophrenic inpatients treated with remoxipride or haloperidol.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzamides; Cognition; Double-Blind Method; Female; Haloperidol; Hospitalization; Humans; Male; Middle Aged; Psychomotor Performance; Remoxipride; Schizophrenia; Schizophrenic Psychology; Time Factors | 1989 |
Remoxipride versus haloperidol in healthy volunteers: psychometric performance and subjective tolerance profiles.
Topics: Adult; Cognition; Double-Blind Method; Flicker Fusion; Haloperidol; Humans; Male; Psychomotor Performance; Reaction Time; Remoxipride; Time Perception | 1995 |
Clinical action of remoxipride.
Topics: Double-Blind Method; Haloperidol; Humans; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
The tolerability and efficacy of the atypical neuroleptic remoxipride compared with clozapine and haloperidol in acute schizophrenia.
Topics: Adult; Basal Ganglia Diseases; Clozapine; Cognition; Double-Blind Method; Drug Tolerance; Emotions; Female; Haloperidol; Humans; Male; Neurologic Examination; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
On dopaminergic modulation of temporal information processing.
Topics: Acoustic Stimulation; Adult; Attention; Brain; Discrimination Learning; Double-Blind Method; Haloperidol; Humans; Male; Receptors, Dopamine D2; Remoxipride | 1993 |
Are there dissociable roles of the mesostriatal and mesolimbocortical dopamine systems on temporal information processing in humans?
Topics: Adult; Arousal; Attention; Basal Ganglia; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Flicker Fusion; Haloperidol; Humans; Limbic System; Male; Mesencephalon; Neural Pathways; Psychomotor Performance; Reaction Time; Receptors, Dopamine D2; Remoxipride; Sensory Thresholds; Sulpiride; Time Perception | 1997 |
Quality of life and response of negative symptoms in schizophrenia to haloperidol and the atypical antipsychotic remoxipride. The Canadian Remoxipride Group.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Quality of Life; Remoxipride; Schizophrenia | 1997 |
The treatment of negative symptoms: a clinical and methodological study.
Topics: Adult; Delayed-Action Preparations; Double-Blind Method; Female; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1999 |
49 other study(ies) available for haloperidol and remoxipride
| Article | Year |
|---|---|
Potential neuroleptic agents. 4. Chemistry, behavioral pharmacology, and inhibition of [3H]spiperone binding of 3,5-disubstituted N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxysalicylamides.
Topics: Animals; Apomorphine; Chemical Phenomena; Chemistry; Corpus Striatum; Haloperidol; Male; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides; Spiperone; Stereotyped Behavior; Structure-Activity Relationship | 1986 |
Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
Topics: Animals; Apomorphine; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonists; Humans; Hyperkinesis; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Salicylamides; Spiperone; Stereotyped Behavior; Structure-Activity Relationship | 1985 |
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.
Topics: Animals; Benzazepines; Brain; CHO Cells; Cricetinae; Dihydroxyphenylalanine; Dopamine D2 Receptor Antagonists; Habituation, Psychophysiologic; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Motor Activity; Optical Rotation; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; Reserpine; Serotonin Antagonists; Spiperone; Structure-Activity Relationship; Transfection | 1994 |
1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding.
Topics: Animals; Antipsychotic Agents; Chlorocebus aethiops; Cloning, Molecular; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Pyrroles; Receptors, Dopamine; Recombinant Proteins; Structure-Activity Relationship | 1995 |
7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Biological Availability; Catalepsy; Chromones; Male; Mice; Molecular Structure; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Structure-Activity Relationship | 1996 |
Design of N-acylprolyltyrosine "tripeptoid" analogues of neurotensin as potential atypical antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurotensin; Rats; Structure-Activity Relationship; Tyrosine | 1998 |
trans-1-[(2-Phenylcyclopropyl)methyl]-4-arylpiperazines: mixed dopamine D(2)/D(4) receptor antagonists as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Dopamine Antagonists; Humans; In Vitro Techniques; Male; Microsomes, Liver; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Dopamine D4; Stereoisomerism; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics.
Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results | 2006 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
High concentrations of the neuroleptic remoxipride block voltage-activated Na+ channels in central and peripheral nerve membranes.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; In Vitro Techniques; Male; Nerve Fibers, Myelinated; Potassium; Rats; Rats, Sprague-Dawley; Remoxipride; Sodium; Sodium Channels; Sulpiride; Xenopus laevis | 1992 |
Subchronic treatment of rats with remoxipride fails to modify sigma binding sites in the brain.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Corpus Striatum; Dopamine Agents; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Liver; Male; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride; Salicylamides | 1992 |
Regional distribution and in vivo binding of the atypical antipsychotic drug remoxipride. A biochemical and autoradiographic analysis in the rat brain.
Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Brain; Brain Chemistry; Chromatography, Liquid; Dopamine Antagonists; Haloperidol; Male; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Remoxipride; Salicylamides | 1992 |
Alterations in regional brain neurotensin concentrations produced by atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzamides; Carbazoles; Caudate Nucleus; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Radioimmunoassay; Rats; Rats, Inbred Strains; Remoxipride; Sulpiride | 1991 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Remoxipride, a new selective D2 antagonist, and haloperidol in cebus monkeys.
Topics: Animals; Antipsychotic Agents; Arousal; Benzamides; Cebus; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Male; Motor Activity; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Receptors, Dopamine D2; Remoxipride | 1990 |
Phencyclidine-induced disruption of an aversely motivated two-choice successive discrimination in the rat.
Topics: Amphetamine; Animals; Antipsychotic Agents; Avoidance Learning; Benzamides; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Haloperidol; Male; Phencyclidine; Rats; Rats, Inbred Strains; Remoxipride | 1990 |
EEG-brain mapping in schizophrenics with predominantly positive and negative symptoms. Comparative studies with remoxipride/haloperidol.
Topics: Adult; Antipsychotic Agents; Behavior; Benzamides; Brain Mapping; Electroencephalography; Female; Hallucinations; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Remoxipride; Schizophrenia; Schizophrenic Psychology | 1990 |
Comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain.
Topics: Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Azepines; Behavior, Animal; Benzamides; Brain; Haloperidol; Levodopa; Male; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Salicylamides | 1988 |
Comparison of the effects of dopamine D1 and D2 receptor antagonists on rat striatal, limbic and nigral dopamine synthesis and utilisation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Benzazepines; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Haloperidol; Homovanillic Acid; Male; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Remoxipride; Substantia Nigra; Sulpiride | 1987 |
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding, Competitive; Brain Chemistry; Catalepsy; Chlorpromazine; Dogs; Female; Haloperidol; Histocytochemistry; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Spiperone; Sulpiride; Thioridazine; Vomiting | 1984 |
Effects of typical and atypical antipsychotic drugs on response decrement patterns in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Remoxipride; Risperidone; Serotonin Antagonists; Sulpiride | 1995 |
The atypical antipsychotic, remoxipride, blocks phencyclidine-induced disruption of prepulse inhibition in the rat.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Clozapine; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Phencyclidine; Raclopride; Rats; Rats, Sprague-Dawley; Reflex, Startle; Remoxipride; Salicylamides | 1994 |
Remoxipride shows low propensity to block functional striatal dopamine D2 receptors in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Calcium; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; In Vitro Techniques; Male; Pergolide; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Remoxipride; Salicylamides; Structure-Activity Relationship; Sulpiride | 1994 |
Phencyclidine- and dizocilpine-induced hyperlocomotion are differentially mediated.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Ergolines; Haloperidol; Male; Motor Activity; Phencyclidine; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remoxipride; Salicylamides | 1994 |
Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells.
Topics: Animals; Antipsychotic Agents; Brain Neoplasms; Cricetinae; Electrophysiology; Haloperidol; Ligands; Membrane Potentials; Mice; Naloxone; Neuroblastoma; Potassium Channels; Receptors, sigma; Remoxipride; Tumor Cells, Cultured | 1994 |
The dopamine D2 antagonist remoxipride acts in vivo on a subpopulation of dopamine D2 receptors.
Topics: Animals; Binding, Competitive; Brain; Catalepsy; Corpus Striatum; Dextroamphetamine; Dose-Response Relationship, Drug; Haloperidol; Limbic System; Male; Motor Activity; Quinolines; Raclopride; Rats; Receptors, Dopamine; Remoxipride; Salicylamides; Substantia Nigra | 1994 |
Stimulation of brain dopamine autoreceptors by remoxipride administration in reserpine-treated male rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Haloperidol; Hydrazines; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Remoxipride; Reserpine; Stimulation, Chemical; Sulpiride | 1993 |
Concentrations of remoxipride and its phenolic metabolites in rat brain and plasma. Relationship to extrapyramidal side effects and atypical antipsychotic profile.
Topics: Animals; Basal Ganglia Diseases; Brain; Catalepsy; Chromatography, High Pressure Liquid; Circadian Rhythm; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Remoxipride; Salicylamides; Spectrophotometry, Ultraviolet | 1993 |
A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex.
Topics: Analysis of Variance; Animals; Autoradiography; Benzamides; Benzazepines; Cerebral Cortex; Clozapine; Haloperidol; Iodine Radioisotopes; Kinetics; Macaca mulatta; Motor Cortex; Prefrontal Cortex; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Remoxipride; Schizophrenia; Somatosensory Cortex; Temporal Lobe; Tritium; Visual Cortex | 1994 |
Dopamine D2 blocking activity and plasma concentrations of remoxipride and its main metabolites in the rat.
Topics: Animals; Body Temperature; Chromatography, High Pressure Liquid; Dopamine D2 Receptor Antagonists; Ergolines; Haloperidol; Hypothermia; Male; Pergolide; Quinpirole; Rats; Rats, Sprague-Dawley; Remoxipride; Salicylamides | 1993 |
[Difference in prolaction response of schizophrenic patients to equivalent doses of haloperidol, remoxipride and sulpiride].
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Middle Aged; Prolactin; Remoxipride; Schizophrenia; Sex Factors; Sulpiride | 1996 |
Enhancement of latent inhibition in the rat by the atypical antipsychotic agent remoxipride.
Topics: Animals; Antipsychotic Agents; Conditioning, Psychological; Haloperidol; Inhibition, Psychological; Male; Rats; Rats, Sprague-Dawley; Remoxipride | 1997 |
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro.
Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Trifluoperazine | 1997 |
Effects of the atypical antipsychotic remoxipride on alcohol self-administration.
Topics: Alcohol Drinking; Animals; Antipsychotic Agents; Central Nervous System Depressants; Conditioning, Operant; Dopamine Antagonists; Ethanol; Haloperidol; Male; Rats; Remoxipride | 1998 |
Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Clozapine; Haloperidol; Imidazoles; Indoles; Injections, Intraperitoneal; Male; Neural Inhibition; Olanzapine; Pirenzepine; Prazosin; Rats; Rats, Wistar; Reflex, Startle; Remoxipride; Risperidone; Ritanserin; Serotonin Antagonists | 1997 |
Pharmacology of [3H]R(+)-7-OH-DPAT binding in the rat caudate-putamen.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Caudate Nucleus; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Guanidines; Guanosine Triphosphate; Haloperidol; Heterotrimeric GTP-Binding Proteins; Indans; Kinetics; Magnesium; Male; Oxazines; Protein Binding; Putamen; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Remoxipride; Sodium; Specific Pathogen-Free Organisms; Sulfones; Sulpiride; Tetrahydronaphthalenes | 2001 |
Effects of antipsychotic drugs on operant responding after acute and repeated administration.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Operant; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Thioridazine; Time Factors | 2002 |
Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration.
Topics: Animals; Antipsychotic Agents; Blotting, Northern; Brain-Derived Neurotrophic Factor; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Rats; Rats, Wistar; Remoxipride; Risperidone; Ritanserin; RNA, Messenger; Time Factors | 2002 |
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases | 2002 |
Effects of novel antipsychotics with mixed D(2) antagonist/5-HT(1A) agonist properties on PCP-induced social interaction deficits in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Aripiprazole; Clozapine; Dioxanes; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Interpersonal Relations; Male; Phencyclidine; Piperazines; Pyridines; Quinolones; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Remoxipride; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Tropanes | 2005 |
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride | 2006 |
Differences among conventional, atypical and novel putative D(2)/5-HT(1A) antipsychotics on catalepsy-associated behaviour in cynomolgus monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Aripiprazole; Benzamides; Benzodiazepines; Benzoxazoles; Catalepsy; Clozapine; Dibenzothiazepines; Dioxanes; Dopamine Antagonists; Female; Haloperidol; Macaca fascicularis; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Remoxipride; Risperidone; Serotonin Receptor Agonists; Thiazoles; Tropanes; Video Recording | 2009 |