haloperidol has been researched along with preclamol in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (28.40) | 18.7374 |
| 1990's | 49 (60.49) | 18.2507 |
| 2000's | 6 (7.41) | 29.6817 |
| 2010's | 3 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| el-Ashmawy, M; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Smith, JD; Yousif, M | 1 |
| Dannals, RF; Ravert, HT; Sonders, MS; Wagner, HN; Weber, E; Wilson, AA | 1 |
| Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF | 1 |
| Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Phillips, G; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF | 1 |
| Carlsson, A; Meier, E; Piercey, MF; Smith, MW; Sonesson, C; Svensson, K; Waters, N; Wikström, H | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Fiechtner, B; Glossmann, H; Hoffmann, RD; Laggner, C; Langer, T; Moebius, FF; Poles, G; Schieferer, C | 1 |
| Carlsson, A; Hansson, L; Lin, CH; Smith, MW; Sonesson, C; Svensson, K; Waters, N; Wikström, H | 1 |
| Pettersson, F; Pontén, H; Sonesson, C; Waters, N; Waters, S | 1 |
| DeHaven-Hudkins, DL; Fleissner, LC | 1 |
| Hudzik, TJ | 1 |
| Araki, H; Hasegawa, Y; Kaku, S; Otomo, S | 1 |
| Ericson, H; Ross, SB | 1 |
| DeHaven-Hudkins, DL; Fleissner, LC; Ford-Rice, FY | 1 |
| Chavkin, C; Connor, MA | 2 |
| Blier, P; de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Codd, EE; Shank, RP | 1 |
| Ross, SB | 1 |
| Musacchio, JM; Zhou, GZ | 1 |
| Itzhak, Y; Stein, I | 1 |
| Karbon, EW; Naper, K; Pontecorvo, MJ | 1 |
| Cler, JA; Contreras, PC; Dilworth, VM; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Battaglia, G; Glennon, RA; Smith, JD | 1 |
| Fiorica-Howells, E; Spector, S | 1 |
| Svensson, L | 1 |
| Church, J; Lodge, D | 1 |
| Itzhak, Y; Krähling, H; Ruhland, M | 1 |
| Klein, M; Musacchio, J; Paturzo, JJ; Zhou, GZ | 1 |
| Bowen, WD; Moses, EL; Tolentino, PJ; Walker, JM | 1 |
| Duckles, SP; Massamiri, T | 1 |
| Culp, SG; De Souza, EB; Wolfe, SA | 1 |
| Bobker, DH; Shen, KZ; Surprenant, A; Williams, JT | 1 |
| Claustre, Y; Fage, D; Scatton, B; Zivkovic, B | 1 |
| Itzhak, Y | 1 |
| Fowler, CJ; Thorell, G | 1 |
| Ahlenius, S; Hillegaart, V | 1 |
| Ahlenius, S; Criborn, CO; Henriksson, C; Hillegaart, V | 1 |
| Bonsall, RW; Michael, RP; Schaefer, GJ | 1 |
| Clark, D; Elam, M; Svensson, TH | 1 |
| Broekkamp, CL; Gower, AJ | 1 |
| Collu, M; Gessa, GL; Serra, G | 1 |
| Carlsson, A; Löfberg, L | 1 |
| Gundlach, AL; Largent, BL; Snyder, SH | 1 |
| Boissard, CG; Delini-Stula, A; Mogilnicka, E | 1 |
| Daus, FJ; Hansen, HA; Plantjé, JF; Stoof, JC | 1 |
| Ahlenius, S; Archer, T; Hillegaart, V; Tandberg, B | 1 |
| Ahlenius, S; Hillegaart, V; Svensson, L; Thorberg, O | 1 |
| Berendsen, HG; Broekkamp, CL; Gower, AJ; Princen, MM | 1 |
| Ahlenius, S; Larsson, K | 1 |
| Fenton, HM; Gerhardt, S; Hall, NR; Liebman, JM; Neale, R; Noreika, L | 1 |
| Geyer, MA; Lee, EH | 1 |
| Carlsson, A; Gunne, LM; Häggström, JE; Wikström, H | 1 |
| Fratta, W; Gessa, GL; Napoli-Farris, L | 1 |
| Bowen, WD; Carr, DJ; DeCosta, BR; Garza, HH; Mayo, S | 1 |
| Appleyard, SM; Chavkin, C; Connor, M; Patterson, TA | 1 |
| Arnold, FJ; Murphy, RB; Schuster, DI | 1 |
| DeCoster, MA; Klette, KL; Knight, ES; Tortella, FC | 1 |
| Bailey, MA; Karbon, EW | 1 |
| Davies, JA; Ellis, Y | 1 |
| Cooper, TB; Klein, M; Musacchio, JM | 1 |
| Barg, J; Eilam, Y; Ela, C; Hasin, Y; Vogel, Z | 1 |
| Gerlach, J; Peacock, L | 1 |
| Enomoto, R; Ogita, K; Yoneda, Y | 1 |
| Callahan, PM; Cunningham, KA | 1 |
| Matsuno, K; Mita, S; Senda, T | 1 |
| Brum, JM; Estafanous, FG; Murray, PA; Schubert, A; Tsuchida, H | 1 |
| Kobayashi, T; Matsuno, K; Mita, S | 1 |
| Barrett, TW; Chang, S; Ha, BK; Liu, Y; Saini, P; Whitlock, BB; Wolfe, SA | 1 |
| Ha, BK; Saini, P; Whitlock, BB; Wolfe, SA | 1 |
| Akiyama, K; Kuroda, S; Okumura, K; Ujike, H | 1 |
| Earley, B; Faherty, CJ; Leonard, BE | 1 |
| Fang, H; Helmeste, DM; Li, M; Tang, SW | 1 |
| Curzon, P; Decker, MW | 1 |
| Carey, JE; Frey, KA; Kilbourn, MR; Kuhl, DE; Mulholland, GK; Sherman, PS; Wieland, DM | 1 |
| Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Minami, M; Nishikawa, H; Satoh, M; Taguchi, R | 1 |
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Burris, KD; Kikuchi, T; Miwa, T; Mori, T; Stark, A; Tadori, Y; Tottori, K | 1 |
| Calas, AG; Goursaud, S; Hermans, E; Jeanjean, AP; Koener, B; Maloteaux, JM; Van De Stadt, M | 1 |
| Carlsson, A; Carlsson, ML; Johansson, AM; Rung, E; Rung, JP; Svensson, K | 1 |
81 other study(ies) available for haloperidol and preclamol
| Article | Year |
|---|---|
Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors.
Topics: Animals; Brain; Guinea Pigs; Microsomes; Phencyclidine; Propylamines; Radioligand Assay; Receptors, Opioid; Receptors, sigma; Substrate Specificity | 1991 |
Radiosynthesis of sigma receptor ligands for positron emission tomography: 11C- and 18F-labeled guanidines.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Fluorine Radioisotopes; Guanidines; Guinea Pigs; Magnetic Resonance Spectroscopy; Receptors, Opioid; Receptors, sigma; Tomography, Emission-Computed | 1991 |
Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
Topics: Animals; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship | 1993 |
Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives.
Topics: Animals; Binding Sites; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes | 1993 |
Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists.
Topics: Animals; Binding Sites; Biological Availability; Brain; Dopamine; Dopamine Antagonists; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship | 1993 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
Topics: Animals; Carrier Proteins; Databases, Factual; Guinea Pigs; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isomerism; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, sigma; Saccharomyces cerevisiae; Sigma-1 Receptor; Steroid Isomerases | 2005 |
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.
Topics: Animals; Benzazepines; Brain; CHO Cells; Cricetinae; Dihydroxyphenylalanine; Dopamine D2 Receptor Antagonists; Habituation, Psychophysiologic; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Motor Activity; Optical Rotation; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; Reserpine; Serotonin Antagonists; Spiperone; Structure-Activity Relationship; Transfection | 1994 |
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Cell Line; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Ligands; Male; Models, Chemical; Molecular Structure; Motor Activity; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2010 |
Competitive interactions at [3H]1,3-di(2-tolyl)guanidine (DTG)-defined sigma recognition sites in guinea pig brain.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Carbazoles; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Male; Pentazocine; Piperidines; Radioligand Assay; Receptors, Opioid; Receptors, sigma | 1992 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Sigma receptor modulation of the muscle relaxant action of eperisone.
Topics: Animals; Behavior, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Haloperidol; In Vitro Techniques; Mice; Mice, Inbred ICR; Muscle Relaxants, Central; Piperidines; Propiophenones; Receptors, Opioid; Receptors, sigma | 1992 |
Subchronic treatment of rats with remoxipride fails to modify sigma binding sites in the brain.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Corpus Striatum; Dopamine Agents; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Liver; Male; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride; Salicylamides | 1992 |
Characterization of the binding of [3H](+)-pentazocine to sigma recognition sites in guinea pig brain.
Topics: Animals; Antipsychotic Agents; Binding Sites; Binding, Competitive; Brain; Carbazoles; Dopamine Agents; Guinea Pigs; Haloperidol; Kinetics; Male; Pentazocine; Piperidines; Receptors, sigma | 1992 |
Ionic zinc may function as an endogenous ligand for the haloperidol-sensitive sigma 2 receptor in rat brain.
Topics: Animals; Binding, Competitive; Brain; Cations, Divalent; Copper; Electric Stimulation; Guanidines; Haloperidol; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Male; Membranes; Pentazocine; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sensitivity and Specificity; Tritium; Zinc | 1992 |
Modulation by sigma ligands of N-methyl-D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency.
Topics: Animals; Calcium; Cinnamates; Cyclopropanes; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pertussis Toxin; Piperidines; Rats; Rats, Inbred Strains; Spiperone; Tritium; Virulence Factors, Bordetella | 1992 |
1,3-Di(2-[5-3H]tolyl)guanidine labels more than one site in rat forebrain.
Topics: Animals; Binding Sites; Binding, Competitive; Carbamazepine; Guanidines; Haloperidol; Male; Pentazocine; Phenytoin; Piperidines; Prosencephalon; Rats; Rats, Wistar; Receptors, sigma; Stereoisomerism | 1992 |
Heterogeneous binding of sigma radioligands in the rat brain and liver: possible relationship to subforms of cytochrome P-450.
Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Guanidines; Haloperidol; Kinetics; Ligands; Liver; Male; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Subcellular Fractions | 1991 |
Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Computer Simulation; Dextromethorphan; Guanidines; Guinea Pigs; Haloperidol; Kinetics; Male; Models, Biological; Piperidines; Receptors, Opioid; Receptors, sigma; Tritium | 1991 |
Regulation of sigma receptors and responsiveness to guanine nucleotides following repeated exposure of rats to haloperidol: further evidence for multiple sigma binding sites.
Topics: Adenosine Triphosphate; Animals; Brain; Cell Membrane; Down-Regulation; Guanidines; Guanine Nucleotides; Guanylyl Imidodiphosphate; Haloperidol; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Reference Values | 1991 |
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Membranes; Phenazocine; Phenytoin; Piperidines; Receptors, Opioid; Receptors, sigma | 1991 |
Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Electric Stimulation; Guanidines; Haloperidol; Hippocampus; Male; Piperidines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1991 |
Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Ligands; Male; Mice; Opipramol; Organ Specificity; Phencyclidine; Piperidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
(-)PPAP: a new and selective ligand for sigma binding sites.
Topics: Animals; Catalysis; Dextroamphetamine; Discrimination, Psychological; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Piperidines; Propylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
Selectivity of some "specific" opioid ligands?
Topics: Animals; Benzomorphans; Binding, Competitive; Brain; Dynorphins; Female; Haloperidol; In Vitro Techniques; Mice; Morphinans; Peptide Fragments; Phencyclidine; Piperidines; Receptors, Opioid | 1990 |
The role of the dopaminergic system in the modulation of the acoustic startle response in the rat.
Topics: Animals; Apomorphine; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Reflex, Startle; Stereoisomerism | 1990 |
Failure of sigma-receptor ligands to reduce the excitatory actions of N-methyl-DL-aspartate on rat spinal neurons in-vivo.
Topics: Animals; Aspartic Acid; Haloperidol; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Stereoisomerism | 1990 |
Binding of umespirone to the sigma receptor: evidence for multiple affinity states.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorpromazine; Guanylyl Imidodiphosphate; Haloperidol; In Vitro Techniques; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine | 1990 |
The effect of sigma ligands on dextromethorphan binding sites in the guinea pig.
Topics: Animals; Binding Sites; Dextromethorphan; Guinea Pigs; Hallucinogens; Haloperidol; In Vitro Techniques; Kinetics; Levorphanol; Piperidines; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors.
Topics: Animals; Brain; Haloperidol; In Vitro Techniques; Male; Motor Activity; Parasympathetic Nervous System; Pentazocine; Phosphatidylinositols; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, sigma | 1990 |
Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.
Topics: Animals; Cocaine; Desoxycorticosterone; Haloperidol; Male; Norepinephrine; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Serotonin; Vasoconstriction | 1990 |
Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary.
Topics: Adrenal Glands; Animals; Autoradiography; Brain Chemistry; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Haloperidol; Hypophysectomy; Male; Ovary; Phencyclidine; Piperidines; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Testis; Tissue Distribution | 1989 |
DTG and (+)-3-PPP inhibit a ligand-activated hyperpolarization in mammalian neurons.
Topics: Animals; Brimonidine Tartrate; Dopamine Agents; Enkephalin, Methionine; Guanidines; Haloperidol; Male; Membrane Potentials; Neurons; Norepinephrine; Piperidines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Serotonin | 1989 |
Relative selectivity of 6,7-dihydroxy-2-dimethylaminotetralin, N-n-propyl-3-(3-hydroxyphenyl)piperidine, N-n-propylnorapomorphine and pergolide as agonists at striatal dopamine autoreceptors and postsynaptic dopamine receptors.
Topics: Acetylcholine; Animals; Apomorphine; Corpus Striatum; Dihydroxyphenylalanine; Ergolines; Haloperidol; Homovanillic Acid; Male; Naphthalenes; Pergolide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sodium Oxybate; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1985 |
Pharmacological specificity of some psychotomimetic and antipsychotic agents for the sigma and PCP binding sites.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Haloperidol; In Vitro Techniques; Male; Phenazocine; Phencyclidine; Piperidines; Psychotropic Drugs; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1988 |
Antagonist effects of the enantiomers of 3-PPP towards alpha 1-adrenoceptors coupled to inositol phospholipid breakdown in the rat cerebral cortex.
Topics: Animals; Antiparkinson Agents; Atropine; Carbachol; Cerebral Cortex; Haloperidol; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Phenoxybenzamine; Piperidines; Prazosin; Raclopride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salicylamides; Stereoisomerism; Sugar Phosphates | 1987 |
Effects of raclopride on exploratory locomotor activity, treadmill locomotion, conditioned avoidance behaviour and catalepsy in rats: behavioural profile comparisons between raclopride, haloperidol and preclamol.
Topics: Animals; Avoidance Learning; Behavior, Animal; Catalepsy; Exploratory Behavior; Haloperidol; Male; Motor Activity; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Salicylamides; Scopolamine | 1987 |
Partial protection against hyperbaric oxygen induced convulsions by dopaminergic agents in mice: possible involvement of autoreceptors?
Topics: Animals; Antiparkinson Agents; Apomorphine; Body Temperature; Dose-Response Relationship, Drug; Haloperidol; Hyperbaric Oxygenation; Levodopa; Male; Mice; Mice, Inbred CBA; Piperidines; Reaction Time; Receptors, Dopamine; Respiration; Seizures | 1987 |
An automatic device for measuring speed of movement and time spent at rest: its application to testing dopaminergic drugs.
Topics: Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Haloperidol; Motor Activity; Neurophysiology; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1986 |
Electrophysiological effects of the enantiomers of 3-PPP on neurons in the locus coeruleus of the rat.
Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Injections, Intravenous; Iontophoresis; Locus Coeruleus; Male; Neurons; Piperidines; Prazosin; Rats; Rats, Inbred Strains; Stereoisomerism; Yohimbine | 1986 |
Dopaminergic agents including 3-PPP and its enantiomers on medial septal self-stimulation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Appetite Depressants; Benzazepines; Dextroamphetamine; Drug Interactions; Haloperidol; Male; Nomifensine; Piperidines; Rats; Receptors, Dopamine; Self Stimulation; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes | 1985 |
Dopamine receptors mediating yawning: are they autoreceptors?
Topics: Animals; Domperidone; Drug Synergism; Haloperidol; Male; Methyltyrosines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reflex; Reserpine; Stereoisomerism; Sulpiride | 1986 |
In vivo displacement by 3-PPP enantiomers of N,N-dipropyl-5,6-ADTN from dopamine receptor-binding sites in rat striatum.
Topics: Animals; Binding, Competitive; Brain; Cerebellum; Corpus Striatum; Haloperidol; Isomerism; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes | 1985 |
Psychotomimetic opiate receptors labeled and visualized with (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine.
Topics: Animals; Brain Mapping; Brain Stem; Cerebellum; Guinea Pigs; Haloperidol; Hypothalamus; Limbic System; Mesencephalon; Piperidines; Rats; Receptors, Dopamine; Receptors, Opioid; Stereoisomerism | 1984 |
Effects of apomorphine, TL-99 and 3-PPP on yawning in rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Behavior, Animal; Haloperidol; Male; Naphthalenes; Piperidines; Rats; Tetrahydronaphthalenes | 1984 |
The effects of SCH 23390, YM 09151-2, (+)- and (-)-3-PPP and some classical neuroleptics on D-1 and D-2 receptors in rat neostriatum in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Antipsychotic Agents; Aporphines; Benzamides; Benzazepines; Caudate Nucleus; Chlorpromazine; Clozapine; Flupenthixol; Haloperidol; In Vitro Techniques; Male; Piperidines; Potassium; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1984 |
Effects of (-)3-PPP on acquisition and retention of a conditioned avoidance response in the rat.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Discrimination Learning; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains | 1984 |
Antagonism by haloperidol of the suppression of exploratory locomotor activity induced by the local application of (-)3-(3-hydroxyphenyl)-N-n-propylpiperidine into the nucleus accumbens of the rat.
Topics: Animals; Exploratory Behavior; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Piperidines; Rats; Rats, Inbred Strains; Septal Nuclei | 1984 |
The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity.
Topics: Animals; Apomorphine; Drug Interactions; Haloperidol; Inhalation; Isomerism; Male; Models, Psychological; Penis; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Respiration; Sexual Behavior, Animal; Syndrome | 1984 |
Apomorphine and haloperidol-induced effects on male rat sexual behavior: no evidence for actions due to stimulation of central dopamine autoreceptors.
Topics: Animals; Apomorphine; Brain; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sexual Behavior, Animal | 1984 |
Avoidance and ICSS behavioral models dissociate TL-99 and 3-PPP from dopamine receptor antagonists.
Topics: Animals; Avoidance Learning; Haloperidol; Male; Models, Psychological; Naphthalenes; Piperidines; Rats; Rats, Inbred F344; Receptors, Dopamine; Saimiri; Self Stimulation; Tetrahydronaphthalenes | 1983 |
Similarities of the effects of apomorphine and 3-PPP on serotonin neurons.
Topics: Animals; Apomorphine; Chromatography, High Pressure Liquid; Corpus Striatum; Haloperidol; Hippocampus; Male; Neurons; Piperidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Spectrometry, Fluorescence | 1983 |
Antidyskinetic action of 3-PPP, a selective dopaminergic autoreceptor agonist, in Cebus monkeys with persistent neuroleptic-induced dyskinesias.
Topics: Animals; Cebus; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Fluphenazine; Haloperidol; Male; Piperidines; Stereoisomerism | 1983 |
Stimulation of dopamine autoreceptors elicits "premature ejaculation" in rats.
Topics: Animals; Apomorphine; Copulation; Domperidone; Dopamine Antagonists; Ejaculation; Female; Haloperidol; Lisuride; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sexual Behavior, Animal | 1984 |
Characterization of a (+)-azidophenazocine-sensitive sigma receptor on splenic lymphocytes.
Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Female; Haloperidol; Interferons; Lymphocytes; Mice; Mice, Inbred C57BL; Phenazocine; Piperidines; Receptors, sigma; Spleen | 1993 |
Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site.
Topics: Animals; Binding Sites; Binding, Competitive; Carbazoles; Dextromethorphan; Female; Guanidines; Haloperidol; Liver; Mazindol; Oocytes; Pentazocine; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, sigma; Xenopus laevis; Zinc | 1994 |
Purification, pharmacological characterization and photoaffinity labeling of sigma receptors from rat and bovine brain.
Topics: Animals; Binding Sites; Cattle; Cerebellum; Dopamine Agonists; Haloperidol; Male; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures.
Topics: Animals; Calcium; Cells, Cultured; Cyclazocine; Cyclopentanes; Dextromethorphan; Glutamic Acid; Guanidines; Haloperidol; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Pentazocine; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Haloperidol treatment differentially regulates [3H]DTG and [3H](+)-3-PPP labeled sigma binding sites.
Topics: Animals; Antipsychotic Agents; Binding Sites; Brain; Dopamine Agents; Drug Administration Schedule; Guanidines; Guinea Pigs; Haloperidol; Male; Phenytoin; Piperidines; Receptors, sigma | 1993 |
The effects of sigma ligands on the release of glutamate from rat striatal slices.
Topics: Animals; Corpus Striatum; Female; Glutamic Acid; Haloperidol; In Vitro Techniques; Ligands; Neuropeptide Y; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, sigma | 1994 |
Effects of haloperidol and reduced haloperidol on binding to sigma sites.
Topics: Animals; Binding Sites; Brain; Dextromethorphan; Guinea Pigs; Haloperidol; Male; Oxidation-Reduction; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1994 |
Sigma receptor ligands modulate contractility, Ca++ influx and beating rate in cultured cardiac myocytes.
Topics: Animals; Calcium; Cells, Cultured; GTP-Binding Proteins; Guanidines; Haloperidol; Heart Rate; Myocardial Contraction; Pentazocine; Piperidines; Rats; Receptors, sigma; Sarcoplasmic Reticulum | 1994 |
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol.
Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzothiazoles; Cebus; Disease Models, Animal; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Dystonia; Ergolines; Female; Haloperidol; Lisuride; Male; Piperidines; Pramipexole; Quinpirole; Raclopride; Salicylamides; Thiazoles | 1993 |
Multiplicity of [3H]1,3-di-o-tolylguanidine binding sites with low affinity for haloperidol in rat brain.
Topics: Animals; Binding Sites; Brain; Guanidines; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1993 |
Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats.
Topics: Animals; Bromocriptine; Cocaine; Discrimination Learning; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 1993 |
Correlation between potentiation of neurogenic twitch contraction and benzomorphan sigma receptor binding potency in the mouse vas deferens.
Topics: Animals; Antiparkinson Agents; Brain; Drug Synergism; Guinea Pigs; Haloperidol; Ligands; Male; Mice; Phenazocine; Piperidines; Receptors, sigma; Spasm; Vas Deferens | 1993 |
Sigma receptor activation does not mediate fentanyl-induced attenuation of muscarinic coronary contraction.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Coronary Vessels; Cyclazocine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fentanyl; Guanidines; Haloperidol; Muscarine; Muscarinic Agonists; Narcotic Antagonists; Narcotics; Pentazocine; Phencyclidine; Piperidines; Potassium Channel Blockers; Receptors, Dopamine; Receptors, sigma; Signal Transduction; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Involvement of sigma-receptors in the increase in contraction of mouse vas deferens induced by exogenous ATP.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Carbazoles; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Haloperidol; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Pentazocine; Phenazocine; Piperidines; Receptors, sigma; Regression Analysis; Structure-Activity Relationship; Vas Deferens | 1996 |
Initial characterization and autoradiographic localization of a novel sigma/opioid binding site in immune tissues.
Topics: Animals; Anticonvulsants; Autoradiography; Binding Sites; Binding, Competitive; Brain Chemistry; Cytochrome P-450 Enzyme System; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Monoamine Oxidase; Naltrexone; Narcotic Antagonists; Narcotics; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spleen; Tritium | 1996 |
Differential localization of three distinct binding sites for sigma receptor ligands in rat spleen.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Autoradiography; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Image Processing, Computer-Assisted; Ligands; Male; Naltrexone; Narcotic Antagonists; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Spleen; Tritium | 1997 |
BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats.
Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dystonia; Guanidines; Haloperidol; Male; Microinjections; Nerve Tissue Proteins; Perphenazine; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, sigma; Red Nucleus; Sulpiride; Torticollis | 1996 |
Behavioural effects of selective serotonin reuptake inhibitors following direct micro injection into the left red nucleus of the rat.
Topics: 1-Naphthylamine; Animals; Behavior, Animal; Chlorpromazine; Citalopram; Fluoxetine; Fluvoxamine; Guanidines; Haloperidol; Male; Microinjections; Motor Activity; Paroxetine; Piperidines; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Selective Serotonin Reuptake Inhibitors; Sertraline | 1997 |
Multiple [3H]-nemonapride binding sites in calf brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Benzamides; Binding, Competitive; Brain; Cattle; Cerebellum; Cerebral Cortex; Corpus Striatum; Dioxanes; Dopamine Agonists; Dopamine Antagonists; Guanidines; Haloperidol; In Vitro Techniques; Isotope Labeling; Narcotic Antagonists; Pentazocine; Piperidines; Propylamines; Pyrrolidines; Receptors, Dopamine D2; Receptors, sigma; Sulpiride; Tritium | 1997 |
Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.
Topics: Acoustic Stimulation; Animals; Apomorphine; Clozapine; Dextroamphetamine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred Strains; Phencyclidine; Piperidines; Rats; Receptors, sigma; Reflex, Startle; Species Specificity | 1998 |
[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses.
Topics: Acetylcholine; Animals; Autoradiography; Brain; Calibration; Carrier Proteins; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Female; Fluorine Radioisotopes; Haloperidol; Humans; Indans; Kinetics; Male; Membrane Transport Proteins; Mice; Organ Specificity; Piperidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synapses; Tissue Distribution; Tomography, Emission-Computed; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 1998 |
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine | 2001 |
Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glucose; Glutamates; Haloperidol; Neurons; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sodium Azide | 2002 |
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; DNA, Complementary; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Humans; Lisuride; Piperazines; Piperidines; Quinolones; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Risperidone; Transfection; Tritium | 2005 |
Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization.
Topics: Animals; Apomorphine; Aripiprazole; Buffers; Catalepsy; Cell Membrane; Cerebral Cortex; Corpus Striatum; Domperidone; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Antagonism; Drug Partial Agonism; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Hippocampus; Male; Piperazines; Piperidines; Pyridines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Stereotyped Behavior; Up-Regulation | 2011 |
Effects of the dopamine stabilizers (S)-(-)-OSU6162 and ACR16 on prolactin secretion in drug-naive and monoamine-depleted rats.
Topics: Animals; Aripiprazole; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Hyperprolactinemia; Lactotrophs; Male; Methyltyrosines; Piperazines; Piperidines; Prolactin; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine | 2011 |