haloperidol has been researched along with piperidines in 415 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 144 (34.70) | 18.7374 |
| 1990's | 144 (34.70) | 18.2507 |
| 2000's | 80 (19.28) | 29.6817 |
| 2010's | 42 (10.12) | 24.3611 |
| 2020's | 5 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Ahtee, L; Kääriäinen, I | 1 |
| Andén, NE; Grabowska, M; Strömbom, U | 1 |
| Andén, NE; Grabowska, M | 1 |
| Arlock, P; Gullberg, B; Olsson, SR | 1 |
| Costall, B; Fortune, DH; Naylor, RJ | 1 |
| Lehmann, K; Schmidt, J | 1 |
| Beckett, PR; Nahorski, SR; Roberts, DJ; Salazar, W | 1 |
| Gerlach, J; Simmelsgaard, H | 1 |
| Koch, MH; Laduron, P; Leysen, J; Tollenaere, JP | 1 |
| Nose, T; Takemoto, H | 1 |
| Buyniski, JP; Doran, KM; Gylys, JA | 1 |
| Laduron, PM; Leysen, JE | 1 |
| Waldmeier, PC | 2 |
| Kraak, JC; van Rooij, HH; Waterman, RL | 1 |
| Lefebvre, RA; Willems, JL | 1 |
| Ishida, R; Ito, K; Kowa, Y; Nurimoto, S; Shintomi, K; Yamamura, M | 1 |
| Lal, H; Niemegeers, CJ; Wauquier, A | 1 |
| Gianutsos, G; Lal, H | 2 |
| Shintomi, K; Yamamura, M | 1 |
| Niemegeers, CJ; Wauquier, A | 2 |
| Kuribara, H; Okuizumi, K; Shirota, M; Tadokoro, S | 1 |
| Andén, NE; Engel, J; Jackson, DM; Liljequist, S | 1 |
| Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH; Wauquier, A | 1 |
| Lindström, E; von Knorring, L | 3 |
| DeHaven-Hudkins, DL; Fleissner, LC | 1 |
| Hudzik, TJ | 1 |
| Araki, H; Hasegawa, Y; Kaku, S; Otomo, S | 1 |
| Ericson, H; Ross, SB | 1 |
| DeHaven-Hudkins, DL; Fleissner, LC; Ford-Rice, FY | 1 |
| Cook, L; Rohrbach, KW; Tam, SW | 1 |
| Fadayel, GM; Schmidt, CJ; Sullivan, CK; Taylor, VL | 1 |
| Awouters, FH; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| Awouters, FH; Megens, AA; Niemegeers, CJ | 2 |
| Gommeren, W; Janssen, PA; Janssen, PM; Leysen, JE; Pauwels, PJ; Wynants, J | 1 |
| Bollen, J; Claus, A; De Cuyper, H; Eneman, M; Heylen, S; Malfroid, M; Peuskens, J | 1 |
| Baert, AL; Bollen, J; Claus, A; De Cuyper, H; Eneman, M; Heylen, S; Malfroid, M; Peuskens, J; Van Ongeval, C; Wilms, G | 1 |
| Müller-Spahn, F | 1 |
| Bowden, CR; De Coster, R; Heykants, J; Voina, SJ; Woestenborghs, R | 1 |
| Chavkin, C; Connor, MA | 2 |
| Blier, P; de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Codd, EE; Shank, RP | 1 |
| Borosky, SA; Clissold, DB; Ferkany, JW; Goode, S; Karbon, EW; Patch, RJ; Pontecorvo, MJ | 1 |
| Pechnick, RN; Vargas, HM | 1 |
| Ross, SB | 1 |
| Musacchio, JM; Zhou, GZ | 1 |
| Itzhak, Y; Stein, I | 1 |
| Karbon, EW; Naper, K; Pontecorvo, MJ | 1 |
| Bakker, MH; Foster, AC | 1 |
| Campbell, AD; Erwin, VG; Jones, BC | 1 |
| Awouters, F; Janssen, PA; Megens, AA; Niemegeers, CJ | 1 |
| Abbate, GM; Nieduzak, TR; Schmidt, CJ; Taylor, VL | 1 |
| Cler, JA; Contreras, PC; Dilworth, VM; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Battaglia, G; Glennon, RA; Smith, JD | 1 |
| Fiorica-Howells, E; Spector, S | 1 |
| Fink, H; Morgenstern, R; Ott, T; Schremmer, C | 1 |
| Svensson, L | 1 |
| Church, J; Lodge, D | 1 |
| Itzhak, Y; Krähling, H; Ruhland, M | 1 |
| Abbate, GM; Black, CK; Schmidt, CJ; Taylor, VL | 1 |
| Hietala, J; Koulu, M; Lappalainen, J; Syvälahti, E | 1 |
| Backus, LI; Grahame-Smith, DG; Sharp, T | 1 |
| Klein, M; Musacchio, J; Paturzo, JJ; Zhou, GZ | 1 |
| Bowen, WD; Moses, EL; Tolentino, PJ; Walker, JM | 1 |
| Duckles, SP; Massamiri, T | 1 |
| Marien, MR; Richard, JW | 1 |
| Reynolds, IJ; Snyder, SH | 1 |
| Lavoie, PA | 1 |
| Awouters, F; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| de Chaffoy de Courcelles, D; Eens, A; Gommeren, W; Janssen, PA; Leysen, JE; Stoof, JC | 1 |
| Cooper, SM; Jackson, D; Loudon, JM; McClelland, GR; Raptopoulos, P | 1 |
| Culp, SG; De Souza, EB; Wolfe, SA | 1 |
| Bobker, DH; Shen, KZ; Surprenant, A; Williams, JT | 1 |
| Diekmann, V; Groezinger, B; Kornhuber, HH; Leibing, U; Rees, J; Scherb, W; Westphal, KP | 1 |
| Altman, HJ; Normile, HJ | 1 |
| Claustre, Y; Fage, D; Scatton, B; Zivkovic, B | 1 |
| Butler, DE; Coughenour, LL; DeWald, HA; Lewis, EP; Lobbestael, SJ; Nordin, IC; Pattison, IC; Poschel, BP; Wise, LD | 1 |
| Gommeren, W; Janssen, PF; Laduron, PM; Leysen, JE; Van Gompel, P; Wynants, J | 1 |
| Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY | 1 |
| Altar, CA; Neale, RF; Stone, GA; Wasley, AM | 1 |
| Baumann, PA; Bischoff, S; Bittiger, H; Hauser, K; Maître, L; Paioni, R; Waldmeier, PC | 1 |
| Itzhak, Y | 1 |
| Forler, C; Fozard, JR; Middlemiss, DN; Tricklebank, MD | 1 |
| Bergstrom, DA; Carlson, JH; Walters, JR | 1 |
| Altar, CA; Marien, MR | 1 |
| Linthicum, DS; Simmons, RD | 1 |
| Candeletti, S; Ferri, S; Romualdi, P; Spadaro, C; Spampinato, S | 1 |
| Fowler, CJ; Thorell, G | 1 |
| Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P | 1 |
| Gibb, JW; Hanson, GR; Johnson, M | 1 |
| Demenge, P; Feuerstein, C; Guerin, B; Mouchet, P; Silice, C | 1 |
| Gerlach, J; Korsgaard, S; Meidahl, B; Noring, U; Povlsen, UJ; Waehrens, J | 1 |
| Estrada, AG; Morera, A; Valenciano, R | 1 |
| Berendsen, HH; Broekkamp, CL | 1 |
| Horisaka, K; Sugimoto, Y; Yamada, J | 1 |
| Ahlenius, S; Hillegaart, V | 1 |
| Ahlenius, S; Criborn, CO; Henriksson, C; Hillegaart, V | 1 |
| Boadle-Biber, MC; Phan, TH | 1 |
| Schechter, MD | 1 |
| Bonsall, RW; Michael, RP; Schaefer, GJ | 1 |
| Clark, D; Elam, M; Svensson, TH | 1 |
| Dvorchik, BH; Pritchard, JF; Renzi, NL; Yorgey, KA | 1 |
| Inanaga, K; Kuniyoshi, M | 1 |
| Broekkamp, CL; Gower, AJ | 1 |
| Collu, M; Gessa, GL; Serra, G | 1 |
| Amore, M; Berlinzani, L; Gentili, C; Giordani, L; Montanari, A | 1 |
| Aguirre Errasti, C; Alonso Alonso, JJ; Castilla Cortázar, A | 1 |
| Christensson, E; Gerlach, J; Korsgaard, S | 1 |
| Carlsson, A; Löfberg, L | 1 |
| Cabeza Gutés, D; Capellà Hereu, D; Laporte Roselló, JR | 1 |
| Ichimura, F; Nakashima, E; Yamana, T; Yokogawa, K | 1 |
| Ekbom, K; Lindholm, H; Ljungberg, L | 1 |
| Rolinski, Z; Scheel-Krüger, J | 1 |
| Hollister, LE | 2 |
| Costall, B; Naylor, RJ | 2 |
| Finch, L | 1 |
| Monti, JM | 1 |
| Angrist, BM; Gershon, S; Phillips, N; Sathanathan, GL | 1 |
| Willems, JL | 1 |
| Akinlaja, A; Opitz, K | 1 |
| Andén, NE; Bédard, P | 1 |
| Chase, TN | 1 |
| Baro, F; Dom, R; van Lommel, R | 3 |
| Honma, T; Inaba, S; Kitagawa, S; Ono, K; Sasajima, K; Yamamoto, H | 1 |
| Bhargava, KP; Rastogi, SK; Sinha, JN | 1 |
| Wurtman, RJ; Yehuda, S | 1 |
| Bost, R; Gallant, DM; Mielke, DH; Spirtes, MA; Swanson, WC | 1 |
| Vandecasteele, AJ; Vereecken, JL | 1 |
| van den Berghe, H | 1 |
| Borisenko, EG; Mel'nik, OB | 1 |
| Koch, MH | 1 |
| Bobon, J; Dufrasne, M; Melon, J; Mormont, C; Pinchard, A | 1 |
| Bass, WC; Brown, H | 1 |
| Baro, F; De Mesmaecker, L; Dom, R; Van Lommel, R | 1 |
| Wagner, M | 1 |
| Funderburk, WH; Johnson, DN; Ward, JW | 1 |
| Nutrikhin, NA; Vasil'eva, EP | 1 |
| Szobor, A | 1 |
| Janssen, PA; Niemegeers, CJ; Verbruggen, FJ | 4 |
| Guliaeva, AI; Nutrikhin, NA; Tsel', VF; Vasil'eva, EP | 1 |
| DaVanzo, JP; Duncan, RL; Funderburk, WH; Helsley, GC; Lunsford, CD; Welstead, WJ | 1 |
| Farcasanu, M; Maniu, M; Uray, Z | 1 |
| Fedukhina, NV; Larionova, RV; Nedashkovskiĭ, EV; Orlov, GA | 1 |
| Leĭtman, AB | 1 |
| Frosali, L; Gigli, M; Salvini, L | 1 |
| Hance, AJ; Monti, JM | 1 |
| Gundlach, AL; Largent, BL; Snyder, SH | 1 |
| Besser, GM; Delitala, G; Grossman, A; Stubbs, WA; Yeo, T | 1 |
| Hyttel, J | 1 |
| Langwiński, R; Malec, D | 1 |
| Boissard, CG; Delini-Stula, A; Mogilnicka, E | 1 |
| Appel, JB; Callahan, PM; Cunningham, KA | 1 |
| Daus, FJ; Hansen, HA; Plantjé, JF; Stoof, JC | 1 |
| Allikmets, LKh; Maĭmets, MO; Nurk, AM; Riago, LK; Vasar, EE | 1 |
| Köhler, C | 1 |
| Ahlenius, S; Archer, T; Hillegaart, V; Tandberg, B | 1 |
| Ahlenius, S; Hillegaart, V; Svensson, L; Thorberg, O | 1 |
| Berendsen, HG; Broekkamp, CL; Gower, AJ; Princen, MM | 1 |
| Ahlenius, S; Larsson, K | 1 |
| Grahame-Smith, DG; Green, AR; Hammond, M; O'Shaughnessy, K; Schächter, M | 1 |
| Fenton, HM; Gerhardt, S; Hall, NR; Liebman, JM; Neale, R; Noreika, L | 1 |
| Geyer, MA; Lee, EH | 1 |
| Carlsson, A; Gunne, LM; Häggström, JE; Wikström, H | 1 |
| Fratta, W; Gessa, GL; Napoli-Farris, L | 1 |
| Shapiro, AK; Shapiro, E | 1 |
| Heninger, GR; Kendler, KS; Roth, RH | 1 |
| Desilva, RD; Falk, RH; Lown, B | 1 |
| Cocchi, D; Gil-Ad, I; Locatelli, V; Müller, EE; Parenti, M; Stefanini, E | 1 |
| Betti, R; Casanueva, F; Cocchi, D; Motta, T; Müller, EE; Zanardi, P | 1 |
| Ereshefsky, L; Lacombe, S | 1 |
| Ciccocioppo, R; Massi, M; Panocka, I; Pompei, P | 1 |
| Janssen, PF; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Czyrak, A; Frankiewicz, T; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Aghajanian, GK; Gellman, RL | 1 |
| Marder, SR; Meibach, RC | 1 |
| Awouters, FH; Janssen, PA | 1 |
| Kido, H; Mori, H; Sakamoto, H; Shiba, K; Sumiyoshi, T; Suzuki, K; Urasaki, K; Yamaguchi, N; Yokogawa, K | 1 |
| McEvoy, JP | 1 |
| Schooler, NR | 1 |
| Owens, DG | 1 |
| Janssen, PM; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Elomaa, E; Raitasuo, V; Vataja, R | 1 |
| Bennett, JA; Keck, PE; Wallhausser, LJ | 1 |
| Jackson, A; Rupniak, NM | 1 |
| Janssen, PM; Leysen, JE; Luyten, WH; Megens, AA; Schotte, A | 1 |
| Beaudry, P; Bélanger, MC; Chouinard, G; Miller, R; Roy, JY; Turnier, L; Vainer, JL | 1 |
| Perrault, G; Sanger, DJ | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Yamada, K | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Ogita, K; Yamada, K; Yoneda, Y | 1 |
| Honer, WG; Kopala, LC | 1 |
| Chouinard, G | 1 |
| DeVane, CL | 1 |
| Perry, PJ | 1 |
| Borison, RL; Chouinard, G; Möller, HJ; Müller, H; Schooler, NR | 1 |
| Jansen, FP; Leurs, R; Prell, GD; Rodrigues, AA; Timmerman, H | 1 |
| Möller, HJ | 1 |
| Kirisci, L; Musser, WS | 1 |
| Benvenga, MJ; Leander, JD | 1 |
| Peuskens, J | 1 |
| Conway, PG; Corbett, R; Cornfeldt, M; Rush, DK; Strupczewski, JT; Szewczak, MR; Wilmot, CA | 1 |
| Deben, SE; Gonzalez-Alvear, GM; Thompson-Montgomery, D; Werling, LL | 1 |
| Hashimoto, K; London, ED; Scheffel, U | 1 |
| Addington, D; Arnott, W; Beauclair, L; Bloom, D; Chouinard, G; Jones, B; Labelle, A; MacEwan, GW; Remington, G | 1 |
| Massi, M; Panocka, I; Pompei, P | 1 |
| Koyama, T; Kusumi, I; Matsubara, R; Matsubara, S; Yamashita, I | 1 |
| Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT | 1 |
| Hayakawa, H; Kawai, K; Kikumoto, O; Motohashi, N; Okamoto, Y; Yamawaki, S; Yokota, N | 1 |
| Matsubara, R | 1 |
| Czyrak, A; Jaros, T; Maj, J; Moryl, E | 1 |
| Kang, DY; Kim, CE; Min, SK; Rhee, CS | 1 |
| Bowen, WD; Carr, DJ; DeCosta, BR; Garza, HH; Mayo, S | 1 |
| Czobor, P; Volavka, J | 1 |
| Cesková, E; Svestka, J | 1 |
| Appleyard, SM; Chavkin, C; Connor, M; Patterson, TA | 1 |
| Arnold, FJ; Murphy, RB; Schuster, DI | 1 |
| DeCoster, MA; Klette, KL; Knight, ES; Tortella, FC | 1 |
| Bailey, MA; Karbon, EW | 1 |
| Davies, JA; Ellis, Y | 1 |
| Cooper, TB; Klein, M; Musacchio, JM | 1 |
| Barg, J; Eilam, Y; Ela, C; Hasin, Y; Vogel, Z | 1 |
| Dannals, RF; Mathews, WB; Musachio, JL; Ravert, HT; Scheffel, U; Stathis, M | 1 |
| Furukawa, K; Hino, K; Karasawa, T; Kurumiya, S; Noda, Y; Ochi, Y; Oka, M; Une, T | 1 |
| Kurumiya, S; Miura, Y; Noda, Y; Oka, M | 1 |
| Gerlach, J; Peacock, L | 1 |
| Efange, SM; Evora, PH; Khare, A; Mach, RH; Michelson, RH; Nowak, PA | 1 |
| Eriksson, L; Ingvar, M; Johansson, B; Parsons, SM; Rogers, GA; Stone-Elander, S; Widén, L | 1 |
| Enomoto, R; Ogita, K; Yoneda, Y | 1 |
| Futuro-Neto, HA; Pires, JG; Ramage, AG; Silva, SR | 1 |
| Callahan, PM; Cunningham, KA | 1 |
| Matsuno, K; Mita, S; Senda, T | 1 |
| Brum, JM; Estafanous, FG; Murray, PA; Schubert, A; Tsuchida, H | 1 |
| Kobayashi, T; Matsuno, K; Mita, S | 1 |
| Barrett, TW; Chang, S; Ha, BK; Liu, Y; Saini, P; Whitlock, BB; Wolfe, SA | 1 |
| Baker, GB; Coutts, RT; Fang, J | 1 |
| Kehne, JH; McCloskey, TC; Padich, RA | 1 |
| Efange, SM; Khare, AB; Langason, RB | 1 |
| Bermoser, K; Glossmann, H; Hanner, M; Moebius, FF; Reiter, RJ | 1 |
| Bush, LG; Davis, K; Gibb, JW; Hanson, GR; Schmidt, CJ; Taylor, VL | 1 |
| Ha, BK; Saini, P; Whitlock, BB; Wolfe, SA | 1 |
| Akiyama, K; Kuroda, S; Okumura, K; Ujike, H | 1 |
| Cordon, JJ; Coughenour, LL | 1 |
| Inoue, Y; Ishida, M; Kaneko, S; Otani, K; Yasui, N | 1 |
| Earley, B; Faherty, CJ; Leonard, BE | 1 |
| Pahk, AJ; Williams, K | 1 |
| Fang, H; Helmeste, DM; Li, M; Tang, SW | 1 |
| Ault, DT; Werling, LL | 1 |
| Vanover, KE | 1 |
| Fischer, TR; Hitchcock, JM; Lister, S; Wettstein, JG | 1 |
| Arvanov, VL; Wang, RY | 1 |
| Stocca, G; Vicini, S | 1 |
| Curzon, P; Decker, MW | 1 |
| Hicks, PB; Richter, TJ; Trompler, RA; Wadenberg, ML; Young, KA; Zavodny, RA | 1 |
| Gallagher, MJ; Huang, H; Lynch, DR | 1 |
| Liang, X; Wang, RY | 1 |
| Bowen, WD; Gulden, ME; John, CS; Li, J; McAfee, JG; Thakur, ML | 1 |
| Dai, J; Ichikawa, J; Kuroki, T; Meltzer, HY | 1 |
| Aizenman, E; Brimecombe, JC; Gallagher, MJ; Lynch, DR | 1 |
| Bermoser, K; Cho, SY; Glossmann, H; Moebius, FF; Paik, YK; Reiter, RJ | 1 |
| Carey, JE; Frey, KA; Kilbourn, MR; Kuhl, DE; Mulholland, GK; Sherman, PS; Wieland, DM | 1 |
| Belpaire, FM; De Vriendt, C; Pan, LP | 1 |
| Bakthavachalam, V; Baldessarini, RJ; Kula, NS; Pounds, S; Tarazi, FI; True, CD; Xu, L | 1 |
| Arai, A; Herbst, TA; Johnson, SA; Knapp, R; Lutz, D; Luu, NT; Lynch, G; Rogers, GA | 1 |
| Blackburn, TP; Holland, V; Kettle, A; Reavill, C; Riley, G | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Nilsson, M; Sorensen, SM; Waters, N; Waters, S | 1 |
| Alsayegh, L; Backstrom, JR; Berry, SA; Friedman, L; Roth, BL; Sanders-Bush, E; Willins, DL | 1 |
| Gueudet, C; Le Fur, G; Santucci, V; Soubrié, P | 1 |
| Chaki, S; Kawashima, N; Nakamura, A; Okuyama, S; Tomisawa, K | 1 |
| Ichikawa, J; Meltzer, HY | 1 |
| Chambers, LK; Greenamyre, JT; Jaw-Tsai, SS; Menniti, FS; Steece-Collier, K | 1 |
| John, C; Leyton, J; Moody, TW | 1 |
| Fushiki, T; Imaizumi, M; Takeda, M | 1 |
| Driouich, R; Motomizu, S; Oshima, M; Takayanagi, T | 1 |
| Ashby, CR; Hashimoto, K; Minabe, Y; Watanabe, KI | 1 |
| Gallagher, MJ; Guttmann, RP; Kurapathi, S; Lynch, DR; Mutel, V; Seifert, KM; Shim, SS | 1 |
| Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J | 1 |
| Browning, JL; Hicks, PB; Wadenberg, MG; Young, KA | 1 |
| Lanis, A; Schmidt, WJ | 1 |
| Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Adams, BW; Moghaddam, B | 1 |
| Carlsson, A; Carlsson, ML; Nilsson, M; Waters, N; Waters, S | 1 |
| Iwado, H; Morita, Y; Shinjo, H; Ueki, A | 1 |
| Cayabyab, FS; Hamming, KS; McRory, JE; Mezeyova, J; Parker, D; Santi, CM; Snutch, TP; Stea, A; Sutton, KG | 1 |
| Fukuda, A; Matsuno, T; Matsuo, T; Motomura, H; Shoge, T; Tashiro, N; Tatebayashi, H; Yokota, K | 1 |
| Arinobu, T; Hattori, H; Ishii, A; Seno, H; Suzuki, O | 1 |
| Dai, J; Ichikawa, J; Meltzer, HY | 1 |
| Garrido Barral, A; González Moneo, MJ | 1 |
| Flumerfelt, BA; Hussain, N; Rajakumar, N | 1 |
| Chaki, S; Funakoshi, T; Hirota, S; Kameo, K; Takamori, K | 1 |
| Ichikawa, J; Liégeois, JF; Meltzer, HY | 1 |
| Alboszta, AR; Bonaccorso, S; Dai, J; Ichikawa, J; Li, Z; Meltzer, HY | 1 |
| Chaki, S; Funakoshi, T; Kawashima, N; Komurasaki, T; Kumagai, T; Nakazato, A; Ogawa, S; Okuyama, S; Suzuki, Y | 1 |
| Bergeron, J; Courtney, C; McConkey, M; Melch, M; Shrikhande, A; Smith, D; Wong, SK | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Minami, M; Nishikawa, H; Satoh, M; Taguchi, R | 1 |
| Dai, J; Ichikawa, J; Li, Z; Meltzer, HY | 1 |
| Kalkman, HO; Loetscher, E | 1 |
| Enz, A; Gemperle, AY; Lüthi, A; Olpe, HR; Pozza, MF | 1 |
| Fahmi, OA; Kalgutkar, AS; Taylor, TJ; Zhou, S | 1 |
| Croft, DL; Hamamoto, DT; Kehl, LJ; Norsted, BD; Simone, DA; Wacnik, PW; Wilcox, GL | 1 |
| Gemperle, AY; McAllister, KH; Olpe, HR | 1 |
| Abekawa, T; Honda, M; Ito, K; Koyama, T | 1 |
| Conway, MW; Heron-Maxwell, C; Monn, JA; O'Neill, MF; Ornstein, P | 1 |
| INGVAR, D; NILSSON, E | 1 |
| DENBER, HC; KAUFFMAN, D; RAJOTTE, P | 1 |
| FUKUCHI, G | 1 |
| ARNOTT, G; MILBLED, G; NAYRAC, P | 1 |
| MARSHALL, BM; TASKER, RR | 1 |
| ARDILLO, L; MAINARDI, C | 1 |
| Cagnotto, A; De Deurwaerdère, P; Marrazzo, A; Mennini, T; Moison, D; Prezzavento, O; Ronsisvalle, G; Spampinato, U | 1 |
| Lee, J; Rajakumar, N | 1 |
| Ablordeppey, SY; Altundas, R; Borne, RF; Fan, P; Li, S; Lyles-Eggleston, M; Schmidt, AW; Shrihkande, A; Sikazwe, DM; Vanase-Frawley, M; Villalobos, A; Xia, J; Yang, Q; Zhang, W; Zhu, X | 1 |
| Baker, LE; Meltzer, HY; Prus, AJ | 1 |
| Nagura, H | 1 |
| Black, ML; Duncan, JN; Toth, LN; Yamazaki, S | 1 |
| Hashimoto, K; Hattori, K; Iyo, M; Yanahashi, S; Yuasa, S | 1 |
| Arvanitis, L; Bauer, D; Meltzer, HY; Rein, W | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Carlsson, A; Carlsson, ML; Gullme, M; Markinhuhta, KR; Nilsson, M; Pettersson, F; Sonesson, C | 1 |
| Dagaev, SG; Dolgo-Saburov, VB; Fil'ko, OA; Glukhova, RI; Khrabrova, AV; Kubarskaya, LG; Mukovskii, LA; Sanotskii, VI | 1 |
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Arya, P; Butler, R; Warner, J | 1 |
| Marona-Lewicka, D; Nichols, DE; Thisted, RA | 1 |
| Cosi, C; Newman-Tancredi, A; Rollet, K; Tesori, V; Waget, A | 1 |
| Burris, KD; Kikuchi, T; Miwa, T; Mori, T; Stark, A; Tadori, Y; Tottori, K | 1 |
| Ballard, ME; Cowart, M; Decker, MW; Esbenshade, TA; Faghih, R; Fox, GB; Hancock, AA; Pan, L; Roberts, S; Rueter, LE; Zhang, M | 1 |
| Carlsson, A; Carlsson, ML; Markinhuhta, KR; Rung, JP | 1 |
| Hayslett, RL; Tizabi, Y | 1 |
| Barth, VN; Chernet, E; Li, D; Martin, LJ; Need, AB; Phebus, LA; Rash, KS | 1 |
| Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M | 1 |
| Hattori, K; Isosaka, T; Iyo, M; Kohsaka, S; Maekawa, M; Sato, T; Uchino, S; Yagi, T; Yuasa, S | 1 |
| Fujii, Y; Higashi, Y; Nakamura, S | 2 |
| Evangelou, A; Kiortsis, DN; Konitsiotis, S; Tsironis, C | 1 |
| Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S | 1 |
| Barlow, KB; Johansson, AM; Kapur, S; Natesan, S; Nobrega, JN; Reckless, GE; Svensson, KA | 1 |
| Arstad, E; Ell, PJ; Erlandsson, K; Pilowsky, LS; Stone, JM; Waterhouse, RN | 1 |
| Benaliouad, F; Kapur, S; Rompré, PP | 1 |
| Egashira, N; Fujiwara, M; Iwasaki, K; Mishima, K; Mizuki, A; Nagai, H; Nishimura, R; Ogata, A; Sano, K; Shoyama, Y | 1 |
| Akhtar, M; Ali, A; Pillai, KK; Uma Devi, P; Vohora, D | 1 |
| Kim, YH; Lee, BJ; Lee, JG | 1 |
| Anderson, GT; Barido, R; Bonhaus, DW; Brann, MR; Brunmark, P; Davis, RE; Dyssegaard, A; Gardell, LR; Hacksell, U; Johnson, RW; Pounds, L; Tabatabaei, A; Vanover, KE; Veinbergs, I | 1 |
| Ballantyne, P; Berghofer, P; Chapman, J; Dikic, B; Greguric, I; Jackson, T; Katsifis, A; Liu, X; Loc'h, C; Mattner, F; Pham, TQ | 1 |
| Andersen, K; Chen, CA; Craig, DA; Daniewska, I; Forray, C; Hegde, LG; Jiang, Y; Kong, R; Li, B; Lu, K; Marzabadi, MR; Mazza, CG; Negron, L; Parola, T; Wetzel, JM; Wolinsky, TD | 1 |
| Akhter, N; Kinuya, S; Mori, H; Nakajima, K; Ogawa, K; Shiba, K | 1 |
| Di Marino, M; Kane, JM; Laska, E; Lauriello, J; Wolfgang, CD | 1 |
| Debeir, O; Decaestecker, C; Kiss, R; Mégalizzi, V; Warzée, N | 1 |
| Burston, JJ; Howard, DR; Kendler, SH; Selley, DE; Sim-Selley, LJ; Wiley, JL | 1 |
| Arad, M; Barak, S; Black, MD; Boulay, D; De Levie, A; Griebel, G; Pichat, P; Varty, GB; Weiner, I | 1 |
| Casti, P; Casu, G; Marchese, G; Pani, L; Ruiu, S; Sanna, A; Spada, GP | 1 |
| Geballe, MT; Low, CM; Ng, FM; Snyder, JP; Traynelis, SF | 1 |
| Benaliouad, F; Kapur, S; Natesan, S; Rompré, PP | 1 |
| Arnt, J; Mørk, A; Witten, LM | 1 |
| Garcia, E; Nakamura, H; Peris, F; Robert, M; Sato, N; Terazawa, Y | 1 |
| Mabrouk, OS; Marti, M; Morari, M | 1 |
| Arrang, JM; Burban, A; Dumoulin, D; Frances, H; Le Pen, G; Rose, C; Sadakhom, C | 1 |
| Imaki, J; Ohno, Y; Okano, M; Okumura, T; Shimizu, S; Tatara, A | 1 |
| Arai, Y; Kikuchi, T; Mitazaki, S; Nakagawasai, O; Nakaya, K; Niijima, F; Onogi, H; Sato, A; Tadano, T; Tan-No, K | 1 |
| Angelucci, F; Bernardi, G; Caltagirone, C; Cantarella, C; Castelli, M; Cavasinni, F; Centonze, D; De Chiara, V; Maccarrone, M; Mataluni, G; Musella, A; Napolitano, F; Rossi, S; Sacchetti, L; Usiello, A | 1 |
| Calas, AG; Goursaud, S; Hermans, E; Jeanjean, AP; Koener, B; Maloteaux, JM; Van De Stadt, M | 1 |
| Bishnoi, M; Chopra, K; Kulkarni, SK; Rongzhu, L | 1 |
| Creed-Carson, M; Nobrega, JN; Oraha, A | 1 |
| Carlsson, A; Carlsson, ML; Johansson, AM; Rung, E; Rung, JP; Svensson, K | 1 |
| Brust, P; Deuther-Conrad, W; Fischer, S; Grosse Maestrup, E; Hiller, A; Maisonial, A; Schepmann, D; Scheunemann, M; Steinbach, J; Wiese, C; Wünsch, B | 1 |
| Asukai, N; Haraguchi, A; Hori, T; Ikeda, K; Ogai, Y; Senoo, E | 1 |
| Ces, A; Kieffer, BL; Ouagazzal, AM; Prinssen, EP; Reiss, D; Walter, O; Wichmann, J | 1 |
| Jardemark, K; Malmerfelt, A; Marcus, MM; Shahid, M; Svensson, TH | 1 |
| Citrome, L; Hochfeld, M; Meng, X; Stahl, SM | 1 |
| Carroll, FI; McMahon, LR; Schulze, DR | 1 |
| Atack, J; Cik, M; De Bruyn, M; Hendrickx, H; Langlois, X; Lavreysen, H; Macdonald, G; Megens, A; Peeters, L; te Riele, P; Vermeire, J; Wouters, R | 1 |
| Ashton, JC; Jain, S; Mandhane, S; Nayak, P; Rajamannar, T; Soni, D | 1 |
| Adelekun, AE; Hannaway, KE; Horiguchi, M; Jayathilake, K; Meltzer, HY | 1 |
| Cvelich, RG; Kincaid, BR; Muzyk, AJ; Preud'homme, XA | 1 |
| Feng, Z; Hou, T; Li, Y | 1 |
| Elkis, H; Hacksell, U; Meltzer, HY; Peters, P; van Kammen, DP; Vanover, K; Weiner, DM | 1 |
| Praharaj, SK; Selvaraj, AG | 1 |
| Baqi, Y; Correa, M; López Cruz, L; Makriyannis, A; Müller, CE; Nunes, EJ; Pardo, M; Randall, PA; Salamone, JD; Vemuri, VK | 1 |
| Gronier, B; Ponten, H; Waters, S | 1 |
| Fijał, K; Nikiforuk, A; Popik, P | 1 |
| Jayarajan, P; Nirogi, R; Shinde, A | 1 |
| Busanello, A; de Freitas, CM; de Moraes Reis, E; Fachinetto, R; Ferreira, J; Figueira, FH; Leal, CQ; Mello, CF; Röpke, J; Villarinho, JG | 1 |
| Kapai, NA; Popova, OV; Rogozin, PD; Skrebitsky, VG; Solntseva, EI | 1 |
| Davoodi, N; Langlois, X; te Riele, P | 1 |
| Boomhower, SR; Rasmussen, EB | 1 |
| Horiguchi, M; Meltzer, HY; Miyauchi, M; Oyamada, Y; Rajagopal, L | 1 |
| Baba, S; Enomoto, T; Ikeda, K; Murai, T; Nakako, T; Ono, M; Shimizu, I | 1 |
| Amato, D; Carey, RJ; de Souza Silva, MA; Groos, D; Huston, JP; Lauber, AC; Müller, CP; Pum, ME | 1 |
| Fujiwara, M; Mizuguchi, Y; Morimoto, T; Ohno, Y; Shimizu, S; Sobue, A | 1 |
| Aracil-Fernández, A; Berbel, P; Manzanares, J; Navarrete, F; Navarro, D; Ortega-Álvaro, A | 1 |
| Bardin, L; Cenci, MA; Depoortère, R; Iderberg, H; Kleven, MS; Koek, W; McCreary, AC; Newman-Tancredi, A; Varney, MA | 1 |
| Masui, A; Minamimoto, S; Mizobe, Y; Mizuguchi, Y; Ochiai, M; Ohno, Y; Shimizu, S; Tamura, M; Tatara, A | 1 |
| Huang, M; Kwon, S; Meltzer, HY; Miyauchi, M; Oyamada, Y; Rajagopal, L | 1 |
| Jain, NS; Tandi, L; Verma, L | 1 |
| Ma, J; Song, Z; Wang, J; Wang, S; Wang, X; Zhao, Q | 1 |
| Harvey, PD; Murasaki, M; Nakamura, H | 1 |
| Alemany-González, M; Chanovas, J; Delgado-Sallent, C; Gener, T; Nebot, P; Puig, MV; Tauste Campo, A | 1 |
| Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S | 1 |
| Hashimoto, N; Ishikawa, S; Ito, YM; Kusumi, I; Okubo, R; Sato, N; Sawagashira, R; Yamamura, R | 1 |
| Nakamura, T; Sasayama, D; Takahashi, K; Washizuka, S; Yokotsuka-Ishida, S | 1 |
| Buyukuysal, RL; Gul, Z; Gursoy, M | 1 |
| Amata, E; Dichiara, M; Fortuna, S; Mamolo, MG; Marrazzo, A; Pasquinucci, L; Romano, M; Turnaturi, R; Zampieri, D | 1 |
| Gotoh, H; Hayashi, Y; Ishikawa, H; Masui, R | 1 |
13 review(s) available for haloperidol and piperidines
| Article | Year |
|---|---|
Calcium-antagonist drugs. Receptor interactions that clarify therapeutic effects.
Topics: Antidiarrheals; Antipsychotic Agents; Brain Chemistry; Calcium; Calcium Channel Blockers; Calcium Channels; Haloperidol; Humans; Ion Channels; Muscles; Piperidines; Receptors, Nicotinic | 1985 |
Neurophysiological evidence that D-1 dopamine receptor blockade attenuates postsynaptic but not autoreceptor-mediated effects of dopamine agonists.
Topics: Animals; Apomorphine; Basal Ganglia; Benzazepines; Dextroamphetamine; Dopamine Antagonists; Electrophysiology; Ergolines; Globus Pallidus; Haloperidol; Ketanserin; Neurons; Pergolide; Piperidines; Quinpirole; Rats; Receptors, Dopamine; Substantia Nigra | 1986 |
Pharmacological profile of risperidone.
Topics: Antipsychotic Agents; Brain; Dose-Response Relationship, Drug; Haloperidol; Humans; Isoxazoles; Metabolic Clearance Rate; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Extrapyramidal side effects and tolerability of risperidone: a review.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists; Drug Therapy, Combination; Female; Fluvoxamine; Haloperidol; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Tic Disorders; Tourette Syndrome | 1994 |
Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Time Factors | 1995 |
Clinical use of the newer antipsychotic drugs.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Female; Formularies as Topic; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1995 |
The negative component in schizophrenia.
Topics: Affective Symptoms; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
[Latest therapies for treating dementia].
Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Cognition; Cohort Studies; Controlled Clinical Trials as Topic; Dementia, Vascular; Donepezil; Female; Fluoxetine; Galantamine; Haloperidol; Hormone Replacement Therapy; Humans; Hydroxychloroquine; Indans; Middle Aged; Nootropic Agents; Piperidines; Placebos; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Trazodone | 2002 |
[Drugs for the treatment of Alzheimer's disease].
Topics: Acetylcholine; Alzheimer Disease; Antidepressive Agents; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Indans; Injections, Intramuscular; Physostigmine; Piperidines; Selective Serotonin Reuptake Inhibitors; Tacrine | 2004 |
Dementia.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Donepezil; Galantamine; Ginkgo biloba; Haloperidol; Humans; Indans; Memantine; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Risperidone; Rivastigmine; Selegiline; Tacrine; Vitamin E | 2004 |
Long-term efficacy and safety of iloperidone: results from 3 clinical trials for the treatment of schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Prospective Studies; Randomized Controlled Trials as Topic; Schizophrenia | 2008 |
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes | 2020 |
36 trial(s) available for haloperidol and piperidines
| Article | Year |
|---|---|
Tardive dyskinesia during and following treatment with haloperidol, haloperidol + biperiden, thioridazine, and clozapine.
Topics: Aged; Biperiden; Clinical Trials as Topic; Clozapine; Dibenzazepines; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Parkinson Disease, Secondary; Piperidines; Psychotic Disorders; Thioridazine | 1978 |
The Swedish version of the Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Construct validity and interrater reliability.
Topics: Antipsychotic Agents; Chronic Disease; Cross-Cultural Comparison; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Observer Variation; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Risperidone; Schizophrenia; Schizophrenic Psychology; Sweden | 1992 |
Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double-blind comparative study.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Female; Haloperidol; Hospitalization; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1992 |
Ventricular enlargement, clinical correlates and treatment outcome in chronic schizophrenic inpatients.
Topics: Adult; Aged; Antipsychotic Agents; Brain; Cerebral Ventricles; Chronic Disease; Dilatation, Pathologic; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, X-Ray Computed | 1992 |
Risperidone in the treatment of chronic schizophrenic patients: an international double-blind parallel-group study versus haloperidol. The International Risperidone Research Group.
Topics: Antipsychotic Agents; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1992 |
The psychomotor effects of paroxetine alone and in combination with haloperidol, amylobarbitone, oxazepam, or alcohol.
Topics: Adult; Amobarbital; Antidepressive Agents; Arousal; Double-Blind Method; Ethanol; Female; Haloperidol; Humans; Male; Middle Aged; Oxazepam; Paroxetine; Piperidines; Psychomotor Performance; Randomized Controlled Trials as Topic; Reaction Time; Serotonin Antagonists | 1989 |
[The effects of neuroleptics on tardive dyskinesias. A video-controlled, randomized study of chlorprothixene, perphenazine, haloperidol and haloperidol + biperiden].
Topics: Aged; Biperiden; Chlorprothixene; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Perphenazine; Piperidines; Random Allocation; Videotape Recording | 1987 |
Assessment of antipsychotic activity of a butyrophenone analogue, lenperone (AHR 2277).
Topics: Benzoates; Butyrophenones; Clinical Trials as Topic; Haloperidol; Humans; Piperidines; Placebos; Psychiatric Status Rating Scales; Schizophrenia | 1974 |
Penfluridol: an efficacious long-acting oral antipsychotic compound.
Topics: Acute Disease; Administration, Oral; Chromatography, Gas; Clinical Trials as Topic; Cooperative Behavior; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Female; Haloperidol; Humans; Hydrocarbons, Halogenated; Male; Motivation; Patients; Piperidines; Placebos; Psychiatric Nursing; Psychiatric Status Rating Scales; Recurrence; Schizophrenia; Tranquilizing Agents | 1974 |
The influence of haloperidol and penfluridol on the learning capacity of the schizophrenic.
Topics: Adult; Clinical Trials as Topic; Haloperidol; Humans; Hydrocarbons, Halogenated; Learning; Male; Middle Aged; Motor Skills; Piperidines; Placebos; Schizophrenia; Toluene; Tranquilizing Agents | 1974 |
A double-blind clinical evaluation of penfluridol (R 16 341) as a maintenance therapy in schizophrenia.
Topics: Adult; Aged; Antiparkinson Agents; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Haloperidol; Hospitalization; Humans; Hydrocarbons, Halogenated; Interview, Psychological; Middle Aged; Piperidines; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Surveys and Questionnaires; Time Factors; Toluene; Tranquilizing Agents | 1974 |
Clastogenic effects of haloperidol in vivo and of haloperidol, droperidol, and pipamperone in vitro. A negative study.
Topics: Adult; Aged; Butyrophenones; Chromosome Aberrations; Clinical Trials as Topic; Culture Media; Droperidol; Haloperidol; Humans; Isonipecotic Acids; Lymphocytes; Male; Middle Aged; Mitosis; Piperidines; Polyploidy; Time Factors; Tranquilizing Agents | 1974 |
[A long-acting neuroleptic. 3. Pilot study of penfluridol (R 16341)].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Electroencephalography; Female; Haloperidol; Humans; Male; Middle Aged; Piperidines; Psychotic Disorders; Time Factors; Tranquilizing Agents | 1970 |
A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent.
Topics: Administration, Oral; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Benzyl Compounds; Clinical Trials as Topic; Delayed-Action Preparations; Evaluation Studies as Topic; Haloperidol; Humans; Injections, Intramuscular; Intraocular Pressure; Male; Middle Aged; Movement Disorders; Parasympatholytics; Piperidines; Piperidones; Placebos; Psychotic Disorders; Tropanes | 1971 |
Risperidone in the treatment of schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Placebos; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Symptoms in schizophrenic syndromes in relation to age, sex, duration of illness and number of previous hospitalizations.
Topics: Adult; Age Factors; Age of Onset; Aged; Antipsychotic Agents; Female; Haloperidol; Hospitalization; Hospitals, Psychiatric; Humans; Isoxazoles; Male; Middle Aged; Patient Admission; Piperidines; Risperidone; Ritanserin; Schizophrenia; Schizophrenic Psychology; Sex Factors | 1994 |
Efficacy of risperidone on positive features of schizophrenia.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Treatment Outcome | 1994 |
Negative symptoms in schizophrenia: assessment of the effect of risperidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia; Single-Blind Method | 1994 |
Changes in single symptoms and separate factors of the schizophrenic syndrome after treatment with risperidone or haloperidol.
Topics: Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
Desmopressin for risperidone-induced enuresis.
Topics: Administration, Intranasal; Adult; Antipsychotic Agents; Deamino Arginine Vasopressin; Double-Blind Method; Enuresis; Female; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Risperidone; Schizophrenia; Schizophrenic Psychology; Sex Characteristics | 1994 |
Effects of risperidone in tardive dyskinesia: an analysis of the Canadian multicenter risperidone study.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1995 |
A path-analytical approach to differentiate between direct and indirect drug effects on negative symptoms in schizophrenic patients. A re-evaluation of the North American risperidone study.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1995 |
The negative component in schizophrenia.
Topics: Affective Symptoms; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Critique of the Canadian Multicenter Placebo-Controlled Study of Risperidone and Haloperidol.
Topics: Canada; Double-Blind Method; Haloperidol; Humans; Isoxazoles; Piperidines; Research Design; Risperidone; Schizophrenia | 1995 |
Risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multi-centre, double-blind, parallel-group study versus haloperidol. Risperidone Study Group.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Neurologic Examination; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Risperidone versus haloperidol in the treatment of chronic schizophrenic patients: a parallel group double-blind comparative trial.
Topics: Adolescent; Adult; Chronic Disease; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1993 |
Quantitative electroencephalogram examination of effects of risperidone in schizophrenic patients.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dominance, Cerebral; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology; Social Behavior | 1993 |
Double-blind comparison of risperidone and haloperidol in schizophrenic and schizoaffective psychoses.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Female; Haloperidol; Humans; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cannabinoids; Double-Blind Method; Drugs, Investigational; Female; Haloperidol; Humans; Male; Middle Aged; Neurotensin; Peptide Fragments; Piperidines; Placebos; Psychotic Disorders; Pyrazoles; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-3; Research Design; Rimonabant; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome | 2004 |
A 12-week, double-blind, placebo-controlled trial of donepezil as an adjunct to haloperidol for treating cognitive impairments in patients with chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Cholinesterase Inhibitors; Chronic Disease; Cognition Disorders; Donepezil; Double-Blind Method; Drug Therapy, Combination; Haloperidol; Humans; Indans; Piperidines; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2007 |
The efficacy and safety of blonanserin compared with haloperidol in acute-phase schizophrenia: a randomized, double-blind, placebo-controlled, multicentre study.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Haloperidol; Humans; International Cooperation; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Schizophrenia; Severity of Illness Index; Young Adult | 2009 |
Efficacy of iloperidone in the short-term treatment of schizophrenia: a post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Labeling; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome; Young Adult | 2012 |
Pimavanserin, a selective serotonin (5-HT)2A-inverse agonist, enhances the efficacy and safety of risperidone, 2mg/day, but does not enhance efficacy of haloperidol, 2mg/day: comparison with reference dose risperidone, 6mg/day.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Follow-Up Studies; Haloperidol; Humans; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Time Factors; Urea; Young Adult | 2012 |
Blonanserin versus haloperidol in Japanese patients with schizophrenia: A phase 3, 8-week, double-blind, multicenter, randomized controlled study.
Topics: Adult; Antipsychotic Agents; Double-Blind Method; Drug Tolerance; Female; Haloperidol; Humans; Male; Middle Aged; Piperazines; Piperidines; Schizophrenia; Weight Gain | 2019 |
367 other study(ies) available for haloperidol and piperidines
| Article | Year |
|---|---|
Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect.
Topics: Analgesics, Opioid; Animals; Body Temperature; Corpus Striatum; Cyclazocine; Haloperidol; Homovanillic Acid; Male; Methadone; Mice; Morphine; Pain; Pentazocine; Phenylacetates; Piperidines; Thebaine; Time Factors | 1976 |
Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System; Clonidine; Dihydroxyphenylalanine; Dioxanes; Dopamine; Female; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Piperidines; Rats; Receptors, Adrenergic; Reflex; Spinal Cord; Tolazoline; Yohimbine | 1976 |
Noradrenaline synthesis and utilization: control by nerve impulse flow under normal conditions and after treatment with alpha-adrenoreceptor blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Brain; Clonidine; Denervation; Dihydroxyphenylalanine; Dioxanes; Dopamine; Haloperidol; Hydrazines; Male; Methyltyrosines; Norepinephrine; Normetanephrine; Phenoxybenzamine; Piperidines; Rats; Spinal Cord; Tolazoline; Tyramine; Yohimbine | 1976 |
Cardiac electrophysiology of four neuroleptics: melperone, haloperidol, thioridazine and chlorpromazine.
Topics: Action Potentials; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Guinea Pigs; Haloperidol; Heart; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Piperidines; Refractory Period, Electrophysiological; Thioridazine | 1978 |
Neuropharmacological studies on the neuroleptic potential of domperidone (R33812).
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzimidazoles; Brain Chemistry; Haloperidol; Humans; Motor Activity; Piperidines; Rats; Stereotyped Behavior | 1979 |
[Effect of psychotropic drugs on somatosensory evoked cortical potentials].
Topics: Animals; Anti-Anxiety Agents; Desipramine; Diazepam; Evoked Potentials; Female; Haloperidol; Hexobarbital; Medazepam; Piperidines; Rats; Somatosensory Cortex | 1979 |
[Clebopride, a new orthopramide with potent and selective central antidopaminergic properties].
Topics: Alprenolol; Animals; Benzamides; Dihydroergotoxine; Haloperidol; Metoclopramide; Piperidines; Rats; Receptors, Dopamine; Sulpiride | 1978 |
Differentiation of opiate and neuroleptic receptor binding in rat brain.
Topics: Animals; Benzimidazoles; Brain; Female; Fentanyl; Haloperidol; Meperidine; Piperidines; Rats; Receptors, Drug; Receptors, Opioid; Spiro Compounds; Structure-Activity Relationship | 1977 |
The effect of penfluridol and some psychotropic drugs on monoamine metabolism in central nervous system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Diazepam; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Norepinephrine; Penfluridol; Pimozide; Piperazines; Piperidines; Psychotropic Drugs; Rats; Serotonin | 1975 |
Antagonism of cisplatin induced emesis in the dog.
Topics: Animals; Antiemetics; Chlorpromazine; Cisplatin; Dogs; Dronabinol; Female; Haloperidol; Indoles; Male; Metoclopramide; Piperidines; Vomiting | 1979 |
Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity.
Topics: Adenylyl Cyclases; Animals; Benzimidazoles; Binding Sites; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Homovanillic Acid; In Vitro Techniques; Piperidines; Rats; Spiperone; Tissue Distribution | 1979 |
Analysis of the activation of dopamine metabolism by a serotonin uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Benzofurans; Corpus Striatum; Dopamine; Female; Haloperidol; Homovanillic Acid; Piperidines; Rats; Scopolamine; Serotonin Antagonists; Time Factors | 1979 |
Dynamic cation-exchange systems for the separation of drugs derived from butyrophenone and diphenylpiperidine by high-performance liquid chromatography and applied in the determination of halopemide in plasma.
Topics: Benzimidazoles; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Domperidone; Haloperidol; Humans; Pimozide; Piperidines; Solvents; Tranquilizing Agents | 1979 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting | 1979 |
[Pharmacological studies of an antipschotic agent, penfluridol. (1). The central pharmacological actions].
Topics: Agonistic Behavior; Animals; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Catalepsy; Cats; Central Nervous System; Chlorpromazine; Conditioning, Classical; Cooperative Behavior; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Haloperidol; Haplorhini; Hexobarbital; Humans; Locomotion; Male; Methamphetamine; Mice; Parasympatholytics; Penfluridol; Piperidines; Rats | 1976 |
Differential antagonism by the antichlolinergic dexetimide of inhibitory effects of haloperidol and fentanyl on brain self-stimulation.
Topics: Animals; Brain; Dexetimide; Dose-Response Relationship, Drug; Fentanyl; Haloperidol; Male; Piperidines; Rats; Self Stimulation | 1975 |
Effect of loperamide, haloperidol and methadone in rats trained to discriminate morphine from saline.
Topics: Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Methadone; Morphine; Piperidines; Rats; Reinforcement Schedule; Sodium Chloride | 1975 |
Effects of penfluridol and other drugs on apomorphine-induced stereotyped behavior in monkeys.
Topics: Animals; Apomorphine; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Haloperidol; Humans; Injections, Subcutaneous; Macaca fascicularis; Male; Methyltyrosines; Nialamide; Penfluridol; Piperidines; Reserpine; Stereotyped Behavior; Time Factors | 1975 |
The effects of dexetimide on pimozide-, haloperidol- and pipamperone-induced inhibition of brain self-stimulation in rats.
Topics: Animals; Brain; Butyrophenones; Depression, Chemical; Dexetimide; Drug Interactions; Electric Stimulation; Haloperidol; Isonipecotic Acids; Male; Pimozide; Piperidines; Rats; Self Stimulation; Tranquilizing Agents | 1975 |
[Effects of penfluridol, a psychotropic agent, on operant behavior of rats].
Topics: Animals; Avoidance Learning; Chlorpromazine; Conditioning, Operant; Haloperidol; Male; Penfluridol; Piperidines; Rats; Reinforcement Schedule | 1975 |
The effect of long-term penfluridol treatment on the sensitivity of the dopamine receptors in the nucleus accumbens and in the corpus striatum.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Humans; Male; Motor Activity; Nialamide; Penfluridol; Piperidines; Rats; Receptors, Drug; Septal Nuclei; Septum Pellucidum; Stereotyped Behavior | 1975 |
Clopimozide (R 29 764), a new highly potent and orally long-acting neuroleptic of the diphenylbutylpiperidine series.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Benzimidazoles; Blepharoptosis; Body Temperature Regulation; Body Weight; Catalepsy; Dextroamphetamine; Dogs; Escape Reaction; Female; Guinea Pigs; Haloperidol; Humans; Lethal Dose 50; Male; Mice; Norepinephrine; Penfluridol; Pimozide; Piperidines; Rats; Self Stimulation; Stereotyped Behavior; Tranquilizing Agents | 1975 |
Alteration in the action of cholinergic and anti cholinergic drugs after chronic haloperidol: indirect evidence for cholinergic hyposensitivity.
Topics: Acetylcholine; Amphetamines; Animals; Dexetimide; Dopamine; Haloperidol; Male; Motor Activity; Pentobarbital; Pilocarpine; Piperidines; Rats; Receptors, Cholinergic; Time Factors | 1976 |
Competitive interactions at [3H]1,3-di(2-tolyl)guanidine (DTG)-defined sigma recognition sites in guinea pig brain.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Carbazoles; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Male; Pentazocine; Piperidines; Radioligand Assay; Receptors, Opioid; Receptors, sigma | 1992 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Sigma receptor modulation of the muscle relaxant action of eperisone.
Topics: Animals; Behavior, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Haloperidol; In Vitro Techniques; Mice; Mice, Inbred ICR; Muscle Relaxants, Central; Piperidines; Propiophenones; Receptors, Opioid; Receptors, sigma | 1992 |
Subchronic treatment of rats with remoxipride fails to modify sigma binding sites in the brain.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Corpus Striatum; Dopamine Agents; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Liver; Male; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride; Salicylamides | 1992 |
Characterization of the binding of [3H](+)-pentazocine to sigma recognition sites in guinea pig brain.
Topics: Animals; Antipsychotic Agents; Binding Sites; Binding, Competitive; Brain; Carbazoles; Dopamine Agents; Guinea Pigs; Haloperidol; Kinetics; Male; Pentazocine; Piperidines; Receptors, sigma | 1992 |
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects.
Topics: Aggression; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Behavior, Animal; Chlorpromazine; Haloperidol; Male; Mescaline; Mice; Mice, Inbred BALB C; Piperidines; Rats; Receptors, Serotonin; Receptors, sigma | 1992 |
5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Dialysis; Dopamine; Fluorobenzenes; Haloperidol; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Antagonists | 1992 |
Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598).
Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Dogs; Dopamine Agents; Dopamine Antagonists; Eating; Female; Haloperidol; Isoxazoles; Lethal Dose 50; Locomotion; Male; Mice; Motor Activity; Muscles; Neurotransmitter Agents; Piperidines; Posture; Pyrimidinones; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Serotonin; Serotonin Antagonists; Synaptic Transmission | 1992 |
Behavioral disinhibition and depression in amphetaminized rats: a comparison of risperidone, ocaperidone and haloperidol.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Isoxazoles; Male; Motor Activity; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Risperidone | 1992 |
In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone.
Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain; Female; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Neurotransmitter Agents; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Risperidone; Spiperone; Tissue Distribution | 1992 |
Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Haloperidol; Isoxazoles; Ketanserin; Male; Piperidines; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Risperidone; Spiro Compounds; Stimulation, Chemical | 1992 |
Ionic zinc may function as an endogenous ligand for the haloperidol-sensitive sigma 2 receptor in rat brain.
Topics: Animals; Binding, Competitive; Brain; Cations, Divalent; Copper; Electric Stimulation; Guanidines; Haloperidol; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Male; Membranes; Pentazocine; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sensitivity and Specificity; Tritium; Zinc | 1992 |
Modulation by sigma ligands of N-methyl-D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency.
Topics: Animals; Calcium; Cinnamates; Cyclopropanes; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pertussis Toxin; Piperidines; Rats; Rats, Inbred Strains; Spiperone; Tritium; Virulence Factors, Bordetella | 1992 |
1,3-Di(2-[5-3H]tolyl)guanidine labels more than one site in rat forebrain.
Topics: Animals; Binding Sites; Binding, Competitive; Carbamazepine; Guanidines; Haloperidol; Male; Pentazocine; Phenytoin; Piperidines; Prosencephalon; Rats; Rats, Wistar; Receptors, sigma; Stereoisomerism | 1992 |
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents.
Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nimodipine; Piperidines; Postural Balance; Pyrimidines; Receptors, Opioid; Receptors, sigma; Seizures | 1991 |
Binding affinity and antimuscarinic activity of sigma and phencyclidine receptor ligands.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Dioxolanes; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pentazocine; Phosphatidylinositols; Piperidines; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine; Scopolamine Derivatives | 1991 |
Heterogeneous binding of sigma radioligands in the rat brain and liver: possible relationship to subforms of cytochrome P-450.
Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Guanidines; Haloperidol; Kinetics; Ligands; Liver; Male; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Subcellular Fractions | 1991 |
Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Computer Simulation; Dextromethorphan; Guanidines; Guinea Pigs; Haloperidol; Kinetics; Male; Models, Biological; Piperidines; Receptors, Opioid; Receptors, sigma; Tritium | 1991 |
Regulation of sigma receptors and responsiveness to guanine nucleotides following repeated exposure of rats to haloperidol: further evidence for multiple sigma binding sites.
Topics: Adenosine Triphosphate; Animals; Brain; Cell Membrane; Down-Regulation; Guanidines; Guanine Nucleotides; Guanylyl Imidodiphosphate; Haloperidol; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Reference Values | 1991 |
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Membranes; Phenazocine; Phenytoin; Piperidines; Receptors, Opioid; Receptors, sigma | 1991 |
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diazepam; Dizocilpine Maleate; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; Injections; Male; Nerve Degeneration; Pipecolic Acids; Piperazines; Piperidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Electric Stimulation; Guanidines; Haloperidol; Hippocampus; Male; Piperidines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1991 |
Regional characterization of brain neurotensin receptor subtypes in LS and SS mice.
Topics: Alcohol Drinking; Animals; Binding, Competitive; Brain; Chlorpheniramine; Haloperidol; Histamine H1 Antagonists; Male; Mice; Mice, Inbred Strains; Neurotensin; Piperidines; Receptors, Neurotensin; Receptors, Neurotransmitter; Sleep Stages; Species Specificity | 1991 |
Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Injections, Intravenous; Isoxazoles; Male; Piperidines; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Seizures; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tryptamines | 1990 |
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Anti-Arrhythmia Agents; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Homovanillic Acid; Levodopa; Male; Nomifensine; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Stereoisomerism; Time Factors | 1991 |
Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Ligands; Male; Mice; Opipramol; Organ Specificity; Phencyclidine; Piperidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
(-)PPAP: a new and selective ligand for sigma binding sites.
Topics: Animals; Catalysis; Dextroamphetamine; Discrimination, Psychological; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Piperidines; Propylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
Selectivity of some "specific" opioid ligands?
Topics: Animals; Benzomorphans; Binding, Competitive; Brain; Dynorphins; Female; Haloperidol; In Vitro Techniques; Mice; Morphinans; Peptide Fragments; Phencyclidine; Piperidines; Receptors, Opioid | 1990 |
Atypical neuroleptics suppress dopaminergic behavioral supersensitivity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Clozapine; Cyproheptadine; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Ritanserin; Serotonin Antagonists; Sulpiride; Thioridazine | 1990 |
The role of the dopaminergic system in the modulation of the acoustic startle response in the rat.
Topics: Animals; Apomorphine; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Reflex, Startle; Stereoisomerism | 1990 |
Failure of sigma-receptor ligands to reduce the excitatory actions of N-methyl-DL-aspartate on rat spinal neurons in-vivo.
Topics: Animals; Aspartic Acid; Haloperidol; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Oxadiazoles; Piperidines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Stereoisomerism | 1990 |
Binding of umespirone to the sigma receptor: evidence for multiple affinity states.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorpromazine; Guanylyl Imidodiphosphate; Haloperidol; In Vitro Techniques; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine | 1990 |
Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Cerebral Cortex; Corpus Striatum; Haloperidol; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists | 1990 |
Neurochemical effects of chronic co-administration of ritanserin and haloperidol: comparison with clozapine effects.
Topics: Animals; Clozapine; Dopamine; Drug Combinations; Haloperidol; Male; Nucleus Accumbens; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Substantia Nigra; Time Factors | 1990 |
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
The effect of sigma ligands on dextromethorphan binding sites in the guinea pig.
Topics: Animals; Binding Sites; Dextromethorphan; Guinea Pigs; Hallucinogens; Haloperidol; In Vitro Techniques; Kinetics; Levorphanol; Piperidines; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors.
Topics: Animals; Brain; Haloperidol; In Vitro Techniques; Male; Motor Activity; Parasympathetic Nervous System; Pentazocine; Phosphatidylinositols; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, sigma | 1990 |
Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.
Topics: Animals; Cocaine; Desoxycorticosterone; Haloperidol; Male; Norepinephrine; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Serotonin; Vasoconstriction | 1990 |
Drug effects on the release of endogenous acetylcholine in vivo: measurement by intracerebral dialysis and gas chromatography-mass spectrometry.
Topics: Acetylcholine; Animals; Atropine; Chromatography, Gas; Consciousness; Corpus Striatum; Dialysis; Haloperidol; Magnesium; Male; Mass Spectrometry; Phencyclidine; Physostigmine; Piperidines; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Penfluridol, chlorprothixene and haloperidol block fast axonal transport in an order of potency consistent with a mechanism related to inhibition of calmodulin.
Topics: Adenosine Triphosphate; Animals; Axonal Transport; Axons; Biomechanical Phenomena; Calmodulin; Chlorprothixene; Haloperidol; In Vitro Techniques; Microtubules; Penfluridol; Phosphocreatine; Piperidines; Rana catesbeiana; Spinal Nerves; Time Factors | 1987 |
Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Conditioning, Psychological; Dogs; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Isoxazoles; Male; Motor Activity; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists | 1988 |
Biochemical profile of risperidone, a new antipsychotic.
Topics: Animals; Antipsychotic Agents; Blood Platelets; Cerebral Cortex; Dopamine; Ergolines; Female; Haloperidol; Isoxazoles; Models, Molecular; Norepinephrine; Oxazoles; Phosphatidic Acids; Piperidines; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Ritanserin; X-Ray Diffraction | 1988 |
Differential effects of the new antipsychotic risperidone on large and small motor movements in rats: a comparison with haloperidol.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Motor Activity; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Risperidone | 1988 |
Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary.
Topics: Adrenal Glands; Animals; Autoradiography; Brain Chemistry; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Haloperidol; Hypophysectomy; Male; Ovary; Phencyclidine; Piperidines; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Testis; Tissue Distribution | 1989 |
DTG and (+)-3-PPP inhibit a ligand-activated hyperpolarization in mammalian neurons.
Topics: Animals; Brimonidine Tartrate; Dopamine Agents; Enkephalin, Methionine; Guanidines; Haloperidol; Male; Membrane Potentials; Neurons; Norepinephrine; Piperidines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Serotonin | 1989 |
Comparison of untreated and treated schizophrenic patients, normals, and neuroleptic-treated normals: "hypofrontality" and different EEG spectra before and during voluntary movement.
Topics: Alpha Rhythm; Biperiden; Electroencephalography; Frontal Lobe; Haloperidol; Humans; Motor Activity; Parietal Lobe; Piperidines; Schizophrenia; Signal Processing, Computer-Assisted; Theta Rhythm | 1989 |
Evidence for a possible interaction between noradrenergic and serotonergic neurotransmission in the retrieval of a previously learned aversive habit in mice.
Topics: Animals; Avoidance Learning; Bicuculline; Brain; Haloperidol; Male; Memory; Mental Recall; Mice; Mice, Inbred Strains; Phenoxybenzamine; Piperidines; Propranolol; Receptors, Adrenergic; Receptors, Serotonin; Retention, Psychology; Scopolamine; Synaptic Transmission; Tranquilizing Agents | 1987 |
Relative selectivity of 6,7-dihydroxy-2-dimethylaminotetralin, N-n-propyl-3-(3-hydroxyphenyl)piperidine, N-n-propylnorapomorphine and pergolide as agonists at striatal dopamine autoreceptors and postsynaptic dopamine receptors.
Topics: Acetylcholine; Animals; Apomorphine; Corpus Striatum; Dihydroxyphenylalanine; Ergolines; Haloperidol; Homovanillic Acid; Male; Naphthalenes; Pergolide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sodium Oxybate; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1985 |
1-[3-(Diarylamino)propyl]piperidines and related compounds, potential antipsychotic agents with low cataleptogenic profiles.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Catalepsy; Corpus Striatum; Haloperidol; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Receptors, Dopamine; Self Stimulation; Structure-Activity Relationship | 1985 |
Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.
Topics: Animals; Binding, Competitive; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Female; Guinea Pigs; Haloperidol; Hippocampus; Histamine H2 Antagonists; In Vitro Techniques; Ketanserin; Kinetics; Male; Organ Specificity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1985 |
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex.
Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride | 1986 |
Typical and atypical antipsychotic occupancy of D2 and S2 receptors: an autoradiographic analysis in rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain; Caudate Nucleus; Haloperidol; Ketanserin; Kinetics; Male; Nucleus Accumbens; Olfactory Bulb; Piperidines; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone | 1986 |
Ifoxetine, a compound with atypical effects on serotonin uptake.
Topics: Animals; Blood Platelets; Brain Chemistry; Corpus Striatum; Haloperidol; In Vitro Techniques; Myocardium; Nalidixic Acid; Naphthyridines; Neurotransmitter Agents; Norepinephrine; Piperidines; Rats; Serotonin; Synaptosomes; Tryptophan; Tyramine; Tyrosine | 1986 |
Pharmacological specificity of some psychotomimetic and antipsychotic agents for the sigma and PCP binding sites.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Haloperidol; In Vitro Techniques; Male; Phenazocine; Phencyclidine; Piperidines; Psychotropic Drugs; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1988 |
Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat.
Topics: Animals; Apomorphine; Behavior, Animal; Betaxolol; Haloperidol; Ketanserin; Male; Pindolol; Piperidines; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Spiperone | 1985 |
[3H]vesamicol binding in brain: autoradiographic distribution, pharmacology, and effects of cholinergic lesions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Autoradiography; Brain; Cholinergic Fibers; Frontal Lobe; Haloperidol; Hippocampus; Image Processing, Computer-Assisted; Ketanserin; Male; Neural Pathways; Neurotransmitter Uptake Inhibitors; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains | 1988 |
A simple 'free 3H-ligand' assay for rapid screening of hybridoma monoclonal antibodies against neurotransmitter analogs and anti-idiotype antibodies.
Topics: Animals; Antibodies, Monoclonal; Haloperidol; Hybridomas; Immunoglobulin Idiotypes; Ketanserin; Mice; Pimozide; Piperidines; Receptors, Neurotransmitter | 1986 |
Studies on the antinociceptive effect of intrathecal salmon calcitonin.
Topics: Analgesics; Animals; Benzomorphans; Calcitonin; Enkephalin, Leucine; Haloperidol; Ketanserin; Male; Methysergide; Nociceptors; Phentolamine; Piperidines; Rats; Receptors, Opioid | 1985 |
Antagonist effects of the enantiomers of 3-PPP towards alpha 1-adrenoceptors coupled to inositol phospholipid breakdown in the rat cerebral cortex.
Topics: Animals; Antiparkinson Agents; Atropine; Carbachol; Cerebral Cortex; Haloperidol; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Phenoxybenzamine; Piperidines; Prazosin; Raclopride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salicylamides; Stereoisomerism; Sugar Phosphates | 1987 |
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior | 1987 |
Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Male; Methamphetamine; Methiothepin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1988 |
Changes of the striatal 3H-spiperone binding 3-6 weeks after nigrostriatal denervation and after two years.
Topics: Animals; Butyrophenones; Corpus Striatum; Denervation; Haloperidol; Hydroxydopamines; Ketanserin; Kinetics; Male; Oxidopamine; Piperidines; Rats; Rats, Inbred Strains; Spiperone; Substantia Nigra; Time Factors | 1985 |
Priapism and neuroleptics: a case report.
Topics: Biperiden; Drug Therapy, Combination; Haloperidol; Humans; Male; Middle Aged; Piperidines; Priapism; Schizophrenia, Paranoid | 1988 |
Drug-induced penile erections in rats: indications of serotonin1B receptor mediation.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Benserazide; Haloperidol; Male; Nialamide; Penile Erection; Piperidines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tranquilizing Agents | 1987 |
The behavioural effects of intravenously administered tryptamine in mice.
Topics: Animals; Behavior, Animal; Brain; Dopamine; Haloperidol; Indoleacetic Acids; Metergoline; Mice; Piperidines; Receptors, Serotonin; Serotonin; Tryptamines | 1987 |
Effects of raclopride on exploratory locomotor activity, treadmill locomotion, conditioned avoidance behaviour and catalepsy in rats: behavioural profile comparisons between raclopride, haloperidol and preclamol.
Topics: Animals; Avoidance Learning; Behavior, Animal; Catalepsy; Exploratory Behavior; Haloperidol; Male; Motor Activity; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Salicylamides; Scopolamine | 1987 |
Partial protection against hyperbaric oxygen induced convulsions by dopaminergic agents in mice: possible involvement of autoreceptors?
Topics: Animals; Antiparkinson Agents; Apomorphine; Body Temperature; Dose-Response Relationship, Drug; Haloperidol; Hyperbaric Oxygenation; Levodopa; Male; Mice; Mice, Inbred CBA; Piperidines; Reaction Time; Receptors, Dopamine; Respiration; Seizures | 1987 |
AGN 2979 [3(3-methoxyphenyl)-3-(3-dimethylaminopropyl)-4, 4-dimethylpiperidine-2,6-dione]. An inhibitor of the activation of tryptophan hydroxylase.
Topics: Animals; Brain Stem; Calmodulin; Enzyme Activation; Gallic Acid; Haloperidol; Male; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Xanthines | 1986 |
Discriminative properties of l-cathinone compared to dl- and d-cathinone.
Topics: Alkaloids; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Stereoisomerism; Time Factors | 1986 |
An automatic device for measuring speed of movement and time spent at rest: its application to testing dopaminergic drugs.
Topics: Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Haloperidol; Motor Activity; Neurophysiology; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1986 |
Electrophysiological effects of the enantiomers of 3-PPP on neurons in the locus coeruleus of the rat.
Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Injections, Intravenous; Iontophoresis; Locus Coeruleus; Male; Neurons; Piperidines; Prazosin; Rats; Rats, Inbred Strains; Stereoisomerism; Yohimbine | 1986 |
Evaluation of drug absorption and presystemic metabolism using an in situ intestinal preparation.
Topics: Animals; Electrolytes; Enzymes; Haloperidol; Intestinal Absorption; Jugular Veins; Male; Pharmaceutical Preparations; Piperidines; Portal Vein; Rats; Rats, Inbred Strains; Tolmetin | 1986 |
Haloperidol and biperiden plasma levels in a pregnant atypical psychotic woman and a neonate--a case report.
Topics: Adult; Biperiden; Female; Haloperidol; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Milk, Human; Piperidines; Pregnancy; Pregnancy Complications; Psychotic Disorders | 1985 |
Dopaminergic agents including 3-PPP and its enantiomers on medial septal self-stimulation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Appetite Depressants; Benzazepines; Dextroamphetamine; Drug Interactions; Haloperidol; Male; Nomifensine; Piperidines; Rats; Receptors, Dopamine; Self Stimulation; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes | 1985 |
Dopamine receptors mediating yawning: are they autoreceptors?
Topics: Animals; Domperidone; Drug Synergism; Haloperidol; Male; Methyltyrosines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reflex; Reserpine; Stereoisomerism; Sulpiride | 1986 |
Pridinolum mesylate and neuroleptic malignant syndrome.
Topics: Adult; Basal Ganglia Diseases; Delusions; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Parasympatholytics; Piperidines; Psychotic Disorders | 1985 |
[Malignant syndrome caused by neuroleptics. Rapid response to biperiden in a case of brief development].
Topics: Biperiden; Haloperidol; Humans; Male; Malignant Hyperthermia; Middle Aged; Piperidines | 1985 |
Behavioral aspects of serotonin-dopamine interaction in the monkey.
Topics: Animals; Chlorocebus aethiops; Cyproheptadine; Dextroamphetamine; Dopamine; Dyskinesia, Drug-Induced; Female; Haloperidol; Male; Mianserin; Motor Activity; Piperidines; Serotonin; Serotonin Antagonists | 1985 |
In vivo displacement by 3-PPP enantiomers of N,N-dipropyl-5,6-ADTN from dopamine receptor-binding sites in rat striatum.
Topics: Animals; Binding, Competitive; Brain; Cerebellum; Corpus Striatum; Haloperidol; Isomerism; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes | 1985 |
[Malignant neuroleptic syndrome and biperiden].
Topics: Biperiden; Haloperidol; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Piperidines | 1985 |
Simultaneous microdetermination of biperiden, haloperidol, and trihexyphenidyl in plasma and its application to pharmacokinetic analysis after concomitant intravenous administration of the drugs to rabbits.
Topics: Animals; Biperiden; Chromatography, Gas; Haloperidol; Injections, Intravenous; Kinetics; Piperidines; Rabbits; Trihexyphenidyl | 1985 |
New dystonic syndrome associated with butyrophenone therapy.
Topics: Amines; Antiparkinson Agents; Basal Ganglia; Butyrophenones; Dementia; Female; Gait; Haloperidol; Humans; Middle Aged; Movement Disorders; Phenothiazines; Piperidines; Posture | 1972 |
The effect of dopamine and noradrenaline antagonists on amphetamine induced locomotor activity in mice and rats.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Aza Compounds; Behavior, Animal; Depression, Chemical; Dopamine Antagonists; Dopamine beta-Hydroxylase; Ergotamine; Female; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Perphenazine; Phenoxybenzamine; Phenyl Ethers; Pimozide; Piperidines; Rats; Receptors, Drug; Spiro Compounds; Time Factors; Tranquilizing Agents; Trifluoperazine | 1973 |
Clinical differences among phenothiazines in schizophrenics. Introduction: specific indications for antipsychotics: elusive end of the rainbow.
Topics: Antipsychotic Agents; Depression; Haloperidol; Humans; Kinetics; Perphenazine; Phenothiazines; Piperazines; Piperidines; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia, Paranoid; Thiothixene; Trifluperidol | 1974 |
The nucleus amygdaloideus centralis and neuroleptic activity in the rat.
Topics: Amygdala; Animals; Behavior; Benzoates; Butyrophenones; Catalepsy; Dextroamphetamine; Dibenzazepines; Dibenzothiazepines; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Humans; Male; Metoclopramide; Piperidines; Rats; Stereotyped Behavior; Time Factors; Tranquilizing Agents | 1974 |
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dioxanes; Dopamine Antagonists; Haloperidol; Heart Rate; Hemodynamics; Hypertension, Renal; Phentolamine; Piperidines; Thiazines; Time Factors; Xylazine | 1974 |
Effects of haloperidol and trifluperidol on the sleep cycle of the cat.
Topics: Animals; Antidepressive Agents; Butyrophenones; Cats; Cerebral Cortex; Fluorine; Haloperidol; Muscles; Piperidines; Sleep; Sleep Stages; Sleep, REM; Trifluperidol; Wakefulness | 1970 |
Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.
Topics: Acetamides; Action Potentials; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Butyrophenones; Catecholamines; Chlorpromazine; Dogs; Dopamine; Dose-Response Relationship, Drug; Ergonovine; Ganglia, Spinal; Haloperidol; Isoproterenol; Methane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Piperidines; Synapses; Synaptic Transmission; Vasodilator Agents | 1973 |
[On the influencing of food intake by psychotropic drugs].
Topics: Amitriptyline; Animals; Behavior, Animal; Body Weight; Central Nervous System; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Eating; Feeding and Eating Disorders; Female; Haloperidol; Humans; Imipramine; Nutritional Physiological Phenomena; Oxazepam; Oxazoles; Pemoline; Phenobarbital; Piperidines; Promethazine; Psychopharmacology; Rats; Reserpine; Thiazines | 1966 |
Influences of cholinergic mechanisms on the function and turnover of brain dopamine.
Topics: Animals; Apomorphine; Atropine; Basal Ganglia; Brain; Catalepsy; Cyclopentanes; Dopamine; Hallucinogens; Haloperidol; Humans; Mandelic Acids; Norepinephrine; Parasympatholytics; Piperidines; Rats; Scopolamine; Trihexyphenidyl | 1971 |
Clinical studies of dopaminergic mechanisms.
Topics: Antiparkinson Agents; Dioxoles; Dopamine; Drug Evaluation; Haloperidol; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Piperidines; Probenecid; Pyrimidines | 1974 |
Interaction between neuroleptic therapy and sociotherapeutic approach an investigation with penfluorid and haloperidol.
Topics: Haloperidol; Humans; Hydrocarbons, Halogenated; Intelligence; Interpersonal Relations; Occupational Therapy; Piperidines; Schizophrenia; Socioenvironmental Therapy; Toluene; Tranquilizing Agents | 1974 |
Synthesis and preliminary pharmacology of a novel butyrophenone derivative, ID-4708.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Butyrophenones; Catalepsy; Cats; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Electroencephalography; Epinephrine; Haloperidol; Hexobarbital; Humans; Hydrocarbons, Fluorinated; Imipramine; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Pain; Piperidines; Rats; Trifluperidol | 1974 |
A comparative study of the central muscle relaxant activity of butyrophenones.
Topics: Animals; Blood Pressure; Butyrophenones; Cats; Droperidol; Female; Haloperidol; Isonipecotic Acids; Leg; Male; Muscle Relaxants, Central; Muscles; Piperidines; Reflex; Synapses; Trifluperidol | 1974 |
Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine.
Topics: Animals; Apomorphine; Brain Chemistry; Clonidine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Drug Combinations; Glycolates; Haloperidol; Hydroxydopamines; Hypothermia; Male; Methysergide; Phenoxybenzamine; Pimozide; Piperidines; Propranolol; Pyrrolidines; Rats; Serotonin; Tyramine | 1972 |
Mesolimbic involvement with behavioural effects indicating antipsychotic activity.
Topics: Animals; Behavior, Animal; Catalepsy; Dextroamphetamine; Dibenzothiazepines; Dose-Response Relationship, Drug; Electrodes, Implanted; Fluphenazine; Haloperidol; Humans; Limbic System; Male; Metoclopramide; Morphine; Piperidines; Rats; Spiro Compounds; Stereotaxic Techniques; Stereotyped Behavior; Tranquilizing Agents | 1974 |
Intracranial self-stimulation in rats as a function of various stimulus parameters. II. Influence of haloperidol, pimozide and pipamperone on medial forebrain bundle stimulation with monopolar electrodes.
Topics: Animals; Electrodes, Implanted; Haloperidol; Hypothalamus; Isonipecotic Acids; Male; Pimozide; Piperidines; Rats; Self Stimulation; Tranquilizing Agents | 1972 |
[Use of haloperidol and promedol in combination with nitrous oxide in liver surgery].
Topics: Adolescent; Adult; Analgesics; Anesthesia; Child; Haloperidol; Humans; Liver Diseases; Middle Aged; Nitrous Oxide; Piperidines | 1973 |
The conformation of neuroleptic drugs.
Topics: Amines; Apomorphine; Benperidol; Butyrophenones; Chlorpromazine; Haloperidol; Hydrogen; Models, Structural; Molecular Conformation; Phenothiazines; Piperidines; Reserpine; Structure-Activity Relationship; Thiothixene; Thioxanthenes; Tranquilizing Agents; X-Ray Diffraction | 1974 |
Effect of drugs on visually controlled avoidance behavior in rhesus monkeys: a psychophysical analysis.
Topics: Anesthetics; Animals; Avoidance Learning; Caffeine; Chlorpromazine; Dextroamphetamine; Escape Reaction; Hallucinogens; Haloperidol; Haplorhini; Lysergic Acid Diethylamide; Male; Morphine; Parasympatholytics; Pentobarbital; Phencyclidine; Piperidines; Psychopharmacology; Size Perception; Strychnine; Visual Perception | 1967 |
Pimozide treatment of chronic schizophrenics as compared with haloperidol and penfluridol maintenance treatment. A multidisciplinary approach.
Topics: Adult; Attention; Benzimidazoles; Chronic Disease; Haloperidol; Humans; Hydrocarbons, Halogenated; Ketones; Male; Memory; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Schizophrenia; Social Behavior; Time Factors; Tranquilizing Agents | 1972 |
[Effect of some common piperidine derivatives on human chromosomes in vitro].
Topics: Benperidol; Chemical Phenomena; Chemistry; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Cyproheptadine; Fentanyl; Glutethimide; Haloperidol; Humans; Hypnotics and Sedatives; In Vitro Techniques; Isonipecotic Acids; Lymphocytes; Mitosis; Mutation; Piperidines; Pyridones; Time Factors; Tranquilizing Agents | 1971 |
Neuropharmacologic analysis of AHR-2277 a new psychotherapeutic agent.
Topics: Amygdala; Animals; Anticonvulsants; Avoidance Learning; Butyrophenones; Cats; Cerebral Cortex; Chlorpromazine; Crowding; Electroencephalography; Evoked Potentials; Female; Haloperidol; Hippocampus; Male; Mice; Piperidines; Tranquilizing Agents | 1971 |
[Neuroleptoanalgesia in emergency surgery].
Topics: Adult; Analgesics; Cholecystitis; Gastrointestinal Hemorrhage; Haloperidol; Humans; Intestinal Obstruction; Male; Neuroleptanalgesia; Nitrous Oxide; Peritonitis; Piperidines; Wounds and Injuries | 1970 |
Results of trifluperidol therapy.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Butyrophenones; Fluorine; Haloperidol; Humans; Mental Disorders; Middle Aged; Piperidines; Trifluperidol | 1969 |
The influence of various neuroleptic drugs on shock avoidance responding in rats. I. Nondiscriminated Sidman avoidance procedure.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Benzimidazoles; Butyrophenones; Chlorpromazine; Depression, Chemical; Electroshock; Escape Reaction; Female; Fluorine; Fluphenazine; Haloperidol; Isonipecotic Acids; Perphenazine; Piperidines; Promazine; Rats; Spiro Compounds; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1969 |
[Neuroleptoanalgesia with haloperidol and promedol].
Topics: Analgesics; Haloperidol; Humans; Neuroleptanalgesia; Piperidines | 1969 |
The influence of various neuroleptic drugs on shock avoidance responding in rats. II. Nondiscriminated Sidman avoidance procedure with alternate reinforcement and extinction periods and analysis of the interresponse times (IRT's).
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Catalepsy; Chlorpromazine; Depression, Chemical; Electroshock; Escape Reaction; Extinction, Psychological; Female; Fluorine; Haloperidol; Humans; Piperidines; Rats; Reinforcement, Psychology; Time Factors; Tranquilizing Agents; Trifluperidol | 1969 |
The influence of various neuroleptic drugs on shock avoidance responding in rats. 3. Amphetamine antagonism in the discriminated Sidman avoidance procedure.
Topics: Amphetamine; Animals; Avoidance Learning; Benzimidazoles; Butyrophenones; Chlorpromazine; Electroshock; Female; Haloperidol; Light; Piperidines; Rats; Sodium Chloride; Tranquilizing Agents | 1970 |
Aroylpiperidines and pyrrolidines. A new class of potent central nervous system depressants.
Topics: Action Potentials; Aggression; Alkylation; Animals; Butyrophenones; Central Nervous System; Chlorpromazine; Depression, Chemical; Electroencephalography; Haloperidol; Hippocampus; Humans; Isonipecotic Acids; Magnesium; Male; Methods; Mice; Nipecotic Acids; Piperidines; Pyrrolidines; Tranquilizing Agents | 1970 |
[Radioprotective properties of butyrophenone derivatives].
Topics: Animals; Antidepressive Agents; Benperidol; Butyrophenones; Fluorine; Haloperidol; Iron Isotopes; Male; Mice; Piperidines; Radiation Injuries, Experimental; Radiation Protection; Radiation-Protective Agents; Trifluperidol | 1970 |
[Elements of neuroleptanalgesia as a component of general anesthesia in high surgical risk patients].
Topics: Adult; Aged; Analgesics; Anesthesia, General; Electrocardiography; Haloperidol; Heart; Humans; Middle Aged; Neuroleptanalgesia; Piperidines | 1970 |
Choice of antipsychotic drugs.
Topics: Butyrophenones; Drug Synergism; Drug Tolerance; Haloperidol; Humans; Phenothiazines; Piperazines; Piperidines; Psychopharmacology; Psychotherapy; Psychotic Disorders; Thioridazine; Thiothixene; Tranquilizing Agents; Triflupromazine; Xanthenes | 1970 |
The influence of various neuroleptic drugs on noise escape response in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Catalepsy; Chlorpromazine; Escape Reaction; Female; Fluorine; Fluphenazine; Haloperidol; Humans; Noise; Perphenazine; Piperidines; Rats; Spiro Compounds; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine | 1970 |
[The effect of a combination of promedol and tranquilizers on the analgesic effect of local anesthetics].
Topics: Analgesics; Anesthesia, Local; Animals; Drug Synergism; Haloperidol; Male; Parasympatholytics; Piperidines; Procaine; Rabbits; Tranquilizing Agents | 1967 |
Haloperidol and trifluperidol in psychiatry.
Topics: Antidepressive Agents; Butyrophenones; Fluorine; Haloperidol; Humans; Piperidines; Psychotic Disorders; Trifluperidol | 1968 |
[Central and peripheral secondary effects of some butyrophenones].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Benperidol; Butyrophenones; Central Nervous System; Extrapyramidal Tracts; Female; Fluorine; Haloperidol; Humans; Male; Middle Aged; Movement Disorders; Peripheral Nerves; Piperidines; Sweating; Trifluperidol | 1969 |
Effects of haloperidol and trifluperidol on operant behavior in the rat.
Topics: Animals; Antidepressive Agents; Butyrophenones; Caffeine; Conditioning, Operant; Fluorine; Haloperidol; Male; Piperidines; Placebos; Rats; Transfer, Psychology; Trifluperidol | 1967 |
Psychotomimetic opiate receptors labeled and visualized with (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine.
Topics: Animals; Brain Mapping; Brain Stem; Cerebellum; Guinea Pigs; Haloperidol; Hypothalamus; Limbic System; Mesencephalon; Piperidines; Rats; Receptors, Dopamine; Receptors, Opioid; Stereoisomerism | 1984 |
Chlorpromazine, haloperidol, metoclopramide and domperidone release prolactin through dopamine antagonism at low concentrations but paradoxically inhibit prolactin release at high concentrations.
Topics: Animals; Antipsychotic Agents; Benzimidazoles; Cells, Cultured; Chlorpromazine; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Metoclopramide; Piperidines; Pituitary Gland, Anterior; Prolactin; Rats | 1980 |
Similarities between the binding of 3H-piflutixol and 3H-flupentixol to rat striatal dopamine receptors in vitro.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Flupenthixol; Half-Life; Haloperidol; Kinetics; Male; Piperidines; Rats; Receptors, Dopamine; Stereoisomerism; Thioxanthenes | 1981 |
The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol.
Topics: Analgesics; Analgesics, Opioid; Animals; Catalepsy; Cimetidine; Diphenhydramine; Drug Interactions; Female; Haloperidol; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains | 1983 |
Effects of apomorphine, TL-99 and 3-PPP on yawning in rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Behavior, Animal; Haloperidol; Male; Naphthalenes; Piperidines; Rats; Tetrahydronaphthalenes | 1984 |
Discriminative stimulus properties of lergotrile.
Topics: Animals; Apomorphine; Discrimination Learning; Dose-Response Relationship, Drug; Ergolines; Ergonovine; Haloperidol; Lisuride; Lysergic Acid Diethylamide; Male; Piperidines; Pizotyline; Quipazine; Rats; Rats, Inbred Strains; Sulpiride | 1984 |
The effects of SCH 23390, YM 09151-2, (+)- and (-)-3-PPP and some classical neuroleptics on D-1 and D-2 receptors in rat neostriatum in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Antipsychotic Agents; Aporphines; Benzamides; Benzazepines; Caudate Nucleus; Chlorpromazine; Clozapine; Flupenthixol; Haloperidol; In Vitro Techniques; Male; Piperidines; Potassium; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1984 |
[Effect of an imidazobenzodiazepine (RO 15-1788) on aggressive behavior in mice].
Topics: Aggression; Animals; Apomorphine; Benzodiazepinones; Brain; Catalepsy; Dose-Response Relationship, Drug; Flumazenil; Haloperidol; Humans; Hydroxyindoleacetic Acid; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1984 |
Autoradiographic mapping of spirodecanone binding-sites in the hippocampal region of the rat. Evidence for a localization on intrinsic neurons.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Mapping; Butyrophenones; Haloperidol; Hippocampus; Ketanserin; Male; Mianserin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Dopamine; Serotonin; Spiperone; Tetrahydronaphthalenes | 1984 |
Effects of (-)3-PPP on acquisition and retention of a conditioned avoidance response in the rat.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Discrimination Learning; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains | 1984 |
Serotoninergic modulation of mesolimbic and frontal cortical dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzofurans; Cerebral Cortex; Corpus Striatum; Dopamine; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Mianserin; Neurons; Organ Specificity; Piperidines; Rats; Serotonin | 1980 |
Antagonism by haloperidol of the suppression of exploratory locomotor activity induced by the local application of (-)3-(3-hydroxyphenyl)-N-n-propylpiperidine into the nucleus accumbens of the rat.
Topics: Animals; Exploratory Behavior; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Piperidines; Rats; Rats, Inbred Strains; Septal Nuclei | 1984 |
The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity.
Topics: Animals; Apomorphine; Drug Interactions; Haloperidol; Inhalation; Isomerism; Male; Models, Psychological; Penis; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Respiration; Sexual Behavior, Animal; Syndrome | 1984 |
Apomorphine and haloperidol-induced effects on male rat sexual behavior: no evidence for actions due to stimulation of central dopamine autoreceptors.
Topics: Animals; Apomorphine; Brain; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sexual Behavior, Animal | 1984 |
Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Haloperidol; Male; Methamphetamine; Motor Activity; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine; Tryptophan | 1983 |
Avoidance and ICSS behavioral models dissociate TL-99 and 3-PPP from dopamine receptor antagonists.
Topics: Animals; Avoidance Learning; Haloperidol; Male; Models, Psychological; Naphthalenes; Piperidines; Rats; Rats, Inbred F344; Receptors, Dopamine; Saimiri; Self Stimulation; Tetrahydronaphthalenes | 1983 |
Similarities of the effects of apomorphine and 3-PPP on serotonin neurons.
Topics: Animals; Apomorphine; Chromatography, High Pressure Liquid; Corpus Striatum; Haloperidol; Hippocampus; Male; Neurons; Piperidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Spectrometry, Fluorescence | 1983 |
Antidyskinetic action of 3-PPP, a selective dopaminergic autoreceptor agonist, in Cebus monkeys with persistent neuroleptic-induced dyskinesias.
Topics: Animals; Cebus; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Fluphenazine; Haloperidol; Male; Piperidines; Stereoisomerism | 1983 |
Stimulation of dopamine autoreceptors elicits "premature ejaculation" in rats.
Topics: Animals; Apomorphine; Copulation; Domperidone; Dopamine Antagonists; Ejaculation; Female; Haloperidol; Lisuride; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sexual Behavior, Animal | 1984 |
Clinical efficacy of haloperidol, pimozide, penfluridol, and clonidine in the treatment of tourette syndrome.
Topics: Child; Child, Preschool; Clonidine; Haloperidol; Humans; Penfluridol; Pimozide; Piperidines; Tourette Syndrome | 1982 |
Brain contribution to the haloperidol-induced increase in plasma homovanillic acid.
Topics: Animals; Benzimidazoles; Brain; Corpus Striatum; Debrisoquin; Domperidone; Haloperidol; Homovanillic Acid; Male; Phenylacetates; Piperidines; Rats; Receptors, Dopamine | 1981 |
Reduction in vulnerability to ventricular fibrillation by bromocriptine, a dopamine agonist.
Topics: Animals; Benzimidazoles; Bromocriptine; Dogs; Domperidone; Dopamine Antagonists; Female; Haloperidol; Male; Piperidines; Ventricular Fibrillation | 1981 |
Prolactin-releasing effect of a novel anti-dopaminergic drug, domperidone, in the rat.
Topics: Animals; Benzimidazoles; Bromocriptine; Caudate Nucleus; Corpus Striatum; Dopamine Antagonists; Haloperidol; Male; Piperidines; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Dopamine; Spiperone | 1980 |
A role for dopamine in growth hormone regulation in the dog.
Topics: Animals; Apomorphine; Atropine; Benzimidazoles; Dogs; Domperidone; Dopamine; Female; Growth Hormone; Haloperidol; Isoquinolines; Kinetics; Male; Nomifensine; Phentolamine; Pimozide; Piperidines | 1981 |
5-HT2 receptor antagonists do not reduce ethanol preference in Sardinian alcohol-preferring (sP) rats.
Topics: Alcohol Drinking; Animals; Antipsychotic Agents; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Risperidone; Ritanserin; Serotonin Antagonists | 1993 |
Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography.
Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Clozapine; Guinea Pigs; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Isoxazoles; Male; Mescaline; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone; Stereotyped Behavior | 1993 |
Pharmacological action of zotepine and other antipsychotics on central 5-hydroxytryptamine receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Clozapine; Dibenzothiepins; Exploratory Behavior; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs.
Topics: Action Potentials; Animals; Antipsychotic Agents; Bicuculline; Cerebral Cortex; Chlorpromazine; Clozapine; Electrophysiology; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Interneurons; Isoxazoles; Male; Membrane Potentials; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists | 1994 |
Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Butyrophenones; Dogs; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; In Vitro Techniques; Isoxazoles; Lysergic Acid Diethylamide; Motor Activity; Neostriatum; Oxygen Consumption; Piperidines; Rats; Risperidone; Schizophrenia; Serotonin Antagonists; Species Specificity; Tryptamines | 1994 |
In vivo dopamine-D2 and serotonin-5-HT2 receptor binding study of risperidone and haloperidol.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Cerebellum; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; In Vitro Techniques; Isoxazoles; Ketanserin; Ligands; Male; Neostriatum; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone | 1994 |
Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.
Topics: Animals; Antipsychotic Agents; Brain; Clone Cells; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; Humans; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 1994 |
Risperidone-induced neuroleptic malignant syndrome in young patient.
Topics: Adult; Antipsychotic Agents; Haloperidol; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Piperidines; Risperidone | 1994 |
Non-specific inhibition of dopamine receptor agonist-induced behaviour by the tachykinin NK1 receptor antagonist CP-99,994 in guinea-pigs.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Dopamine Agonists; Grooming; Guinea Pigs; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oxazines; Piperidines; Receptors, Neurokinin-1; Stereoisomerism; Substance P | 1994 |
Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.
Topics: Animals; Antipsychotic Agents; Autoradiography; Clozapine; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone | 1993 |
Effects of typical and atypical antipsychotic drugs on response decrement patterns in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Remoxipride; Risperidone; Serotonin Antagonists; Sulpiride | 1995 |
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Isoxazoles; Locomotion; Male; Phencyclidine; Piperidines; Random Allocation; Rats; Rats, Wistar; Risperidone; Ritanserin; Schizophrenia; Serotonin; Stereotyped Behavior | 1994 |
Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Drug Tolerance; Haloperidol; Isoxazoles; Male; Methamphetamine; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, Serotonin; Risperidone; Ritanserin | 1995 |
Schizophrenia and severe tardive dyskinesia responsive to risperidone.
Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Neurologic Examination; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Interaction of clozapine with the histamine H3 receptor in rat brain.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clozapine; Haloperidol; Histamine Antagonists; Histamine Release; Imidazoles; Isothiuronium; Methylhistamines; Piperidines; Rats; Receptors, Histamine H3 | 1995 |
Olanzapine, an atypical antipsychotic, increases rates of punished responding in pigeons.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Clozapine; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Olanzapine; Piperidines; Pirenzepine; Punishment; Risperidone | 1995 |
The pharmacological profile of iloperidone, a novel atypical antipsychotic agent.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Dopamine Antagonists; Haloperidol; Isoxazoles; Male; Mice; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Risperidone; Saimiri; Serotonin Antagonists | 1995 |
Functional and binding properties of sigma receptors in rat cerebellum.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclohexylamines; Female; Glycine; Haloperidol; Male; N-Methylaspartate; Norepinephrine; Pentazocine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stereoisomerism | 1995 |
In vivo labeling of sigma receptors in mouse brain with [3H]4-phenyl-1-(4-phenylbutyl)piperidine.
Topics: Animals; Binding, Competitive; Brain Chemistry; Haloperidol; Injections, Intravenous; Ligands; Male; Mice; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1995 |
Suppression of alcohol preference in rats induced by risperidone, a serotonin 5-HT2 and dopamine D2 receptor antagonist.
Topics: Alcohol Drinking; Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists | 1993 |
Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.
Topics: Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Haloperidol; Isoxazoles; Male; Piperidines; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Risperidone; Serotonin Antagonists | 1993 |
Effects of atypical antipsychotic agents on social behavior in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior | 1993 |
[Effects of risperidone on catalepsy and cerebral dopamine, serotonin and GABA metabolism in the rat: comparison with haloperidol].
Topics: Animals; Antipsychotic Agents; Brain; Catalepsy; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Serotonin | 1993 |
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain].
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1993 |
Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone | 1993 |
Characterization of a (+)-azidophenazocine-sensitive sigma receptor on splenic lymphocytes.
Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Female; Haloperidol; Interferons; Lymphocytes; Mice; Mice, Inbred C57BL; Phenazocine; Piperidines; Receptors, sigma; Spleen | 1993 |
Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site.
Topics: Animals; Binding Sites; Binding, Competitive; Carbazoles; Dextromethorphan; Female; Guanidines; Haloperidol; Liver; Mazindol; Oocytes; Pentazocine; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, sigma; Xenopus laevis; Zinc | 1994 |
Purification, pharmacological characterization and photoaffinity labeling of sigma receptors from rat and bovine brain.
Topics: Animals; Binding Sites; Cattle; Cerebellum; Dopamine Agonists; Haloperidol; Male; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures.
Topics: Animals; Calcium; Cells, Cultured; Cyclazocine; Cyclopentanes; Dextromethorphan; Glutamic Acid; Guanidines; Haloperidol; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Pentazocine; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Haloperidol treatment differentially regulates [3H]DTG and [3H](+)-3-PPP labeled sigma binding sites.
Topics: Animals; Antipsychotic Agents; Binding Sites; Brain; Dopamine Agents; Drug Administration Schedule; Guanidines; Guinea Pigs; Haloperidol; Male; Phenytoin; Piperidines; Receptors, sigma | 1993 |
The effects of sigma ligands on the release of glutamate from rat striatal slices.
Topics: Animals; Corpus Striatum; Female; Glutamic Acid; Haloperidol; In Vitro Techniques; Ligands; Neuropeptide Y; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, sigma | 1994 |
Effects of haloperidol and reduced haloperidol on binding to sigma sites.
Topics: Animals; Binding Sites; Brain; Dextromethorphan; Guinea Pigs; Haloperidol; Male; Oxidation-Reduction; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1994 |
Sigma receptor ligands modulate contractility, Ca++ influx and beating rate in cultured cardiac myocytes.
Topics: Animals; Calcium; Cells, Cultured; GTP-Binding Proteins; Guanidines; Haloperidol; Heart Rate; Myocardial Contraction; Pentazocine; Piperidines; Rats; Receptors, sigma; Sarcoplasmic Reticulum | 1994 |
(+)-[C-11]-cis-N-benzyl-normetazocine: a selective ligand for sigma receptors in vivo.
Topics: Animals; Binding, Competitive; Brain; Carbon Radioisotopes; Cyclazocine; Haloperidol; Kinetics; Ligands; Male; Mice; Organ Specificity; Pentazocine; Phencyclidine; Piperidines; Receptors, sigma; Spiperone; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed | 1994 |
Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Biogenic Monoamines; Clozapine; Dogs; Dopamine D2 Receptor Antagonists; Guinea Pigs; Haloperidol; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Neurotransmitter Uptake Inhibitors; Piperazines; Piperidines; Prosencephalon; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tritium | 1993 |
Comparative study of 2-(4-ethyl-1-piperazinyl)-4-(fluorophenyl)-5,6,7,8,9, 10-hexahydrocycloocta[b]pyridine (AD-5423) and haloperidol for their pharmacological activities related to antipsychotic efficacy and/or adverse side-effects.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Brain; Drug Synergism; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Dopamine; Veratrine | 1993 |
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol.
Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzothiazoles; Cebus; Disease Models, Animal; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Dystonia; Ergolines; Female; Haloperidol; Lisuride; Male; Piperidines; Pramipexole; Quinpirole; Raclopride; Salicylamides; Thiazoles | 1993 |
p-[18F]fluorobenzyltrozamicol ([18F]FBT): molecular decomposition- reconstitution approach to vesamicol receptor radioligands for positron emission tomography.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Fluorine Radioisotopes; Fluorobenzenes; Haloperidol; Hippocampus; Isotope Labeling; Male; Piperidines; Rats; Receptors, Cholinergic; Time Factors | 1994 |
Striatal D2/acetylcholine interactions: PET studies of the vesamicol receptor.
Topics: Acetylcholine; Animals; Autoradiography; Benzazepines; Brain; Corpus Striatum; Dopamine D2 Receptor Antagonists; Fluoroacetates; Haloperidol; Macaca fascicularis; Piperidines; Rats; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereoisomerism; Tomography, Emission-Computed | 1993 |
Multiplicity of [3H]1,3-di-o-tolylguanidine binding sites with low affinity for haloperidol in rat brain.
Topics: Animals; Binding Sites; Brain; Guanidines; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1993 |
Effects of the 5-HT receptor antagonists cyanopindolol, ICI 169,369, cisapride and granisetron on neuroleptic-induced catalepsy in mice.
Topics: Animals; Buspirone; Catalepsy; Cisapride; Female; Granisetron; Haloperidol; Male; Mice; Pindolol; Piperidines; Quinolines; Serotonin Antagonists; Time Factors | 1993 |
Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats.
Topics: Animals; Bromocriptine; Cocaine; Discrimination Learning; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 1993 |
Correlation between potentiation of neurogenic twitch contraction and benzomorphan sigma receptor binding potency in the mouse vas deferens.
Topics: Animals; Antiparkinson Agents; Brain; Drug Synergism; Guinea Pigs; Haloperidol; Ligands; Male; Mice; Phenazocine; Piperidines; Receptors, sigma; Spasm; Vas Deferens | 1993 |
Sigma receptor activation does not mediate fentanyl-induced attenuation of muscarinic coronary contraction.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Coronary Vessels; Cyclazocine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fentanyl; Guanidines; Haloperidol; Muscarine; Muscarinic Agonists; Narcotic Antagonists; Narcotics; Pentazocine; Phencyclidine; Piperidines; Potassium Channel Blockers; Receptors, Dopamine; Receptors, sigma; Signal Transduction; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Involvement of sigma-receptors in the increase in contraction of mouse vas deferens induced by exogenous ATP.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Carbazoles; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Haloperidol; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Pentazocine; Phenazocine; Piperidines; Receptors, sigma; Regression Analysis; Structure-Activity Relationship; Vas Deferens | 1996 |
Initial characterization and autoradiographic localization of a novel sigma/opioid binding site in immune tissues.
Topics: Animals; Anticonvulsants; Autoradiography; Binding Sites; Binding, Competitive; Brain Chemistry; Cytochrome P-450 Enzyme System; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Monoamine Oxidase; Naltrexone; Narcotic Antagonists; Narcotics; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spleen; Tritium | 1996 |
Determination of 4-(4-chlorophenyl)-4-hydroxypiperidine, a metabolite of haloperidol, by gas chromatography with electron-capture detection.
Topics: Animals; Chromatography, Gas; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 1996 |
5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100,907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats.
Topics: Amphetamines; Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Fenfluramine; Fluorobenzenes; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reflex, Startle; Serotonin Receptor Agonists | 1996 |
Age-related diminution of dopamine antagonist-stimulated vesamicol receptor binding.
Topics: Aging; Animals; Brain; Dopamine Antagonists; Haloperidol; Iodine Radioisotopes; Iodobenzenes; Male; Piperidines; Radionuclide Imaging; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Cholinergic; Salicylamides; Time Factors | 1996 |
Yeast sterol C8-C7 isomerase: identification and characterization of a high-affinity binding site for enzyme inhibitors.
Topics: Animals; Base Sequence; Binding Sites; DNA Primers; Enzyme Inhibitors; Ergosterol; Guinea Pigs; Haloperidol; Kinetics; Ligands; Mutation; Piperidines; Receptors, sigma; Saccharomyces cerevisiae; Steroid Isomerases; Trifluperidol | 1996 |
Comparison of neurotensin responses to MDL 100,907, a selective 5HT2A antagonist, with clozapine and haloperidol.
Topics: Animals; Caudate Nucleus; Clozapine; Fluorobenzenes; Globus Pallidus; Haloperidol; Male; Neurotensin; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 1997 |
Differential localization of three distinct binding sites for sigma receptor ligands in rat spleen.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Autoradiography; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Image Processing, Computer-Assisted; Ligands; Male; Naltrexone; Narcotic Antagonists; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Spleen; Tritium | 1997 |
BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats.
Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dystonia; Guanidines; Haloperidol; Male; Microinjections; Nerve Tissue Proteins; Perphenazine; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, sigma; Red Nucleus; Sulpiride; Torticollis | 1996 |
Characterization of haloperidol and trifluperidol as subtype-selective N-methyl-D-aspartate (NMDA) receptor antagonists using [3H]TCP and [3H]ifenprodil binding in rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Female; Haloperidol; Illicit Drugs; Kinetics; Oocytes; Phencyclidine; Piperidines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Trifluperidol; Xenopus | 1997 |
Possible interaction between cisapride and bromperidol.
Topics: Adult; Cisapride; Drug Interactions; Haloperidol; Humans; Male; Piperidines; Schizophrenia; Sympathomimetics | 1997 |
Behavioural effects of selective serotonin reuptake inhibitors following direct micro injection into the left red nucleus of the rat.
Topics: 1-Naphthylamine; Animals; Behavior, Animal; Chlorpromazine; Citalopram; Fluoxetine; Fluvoxamine; Guanidines; Haloperidol; Male; Microinjections; Motor Activity; Paroxetine; Piperidines; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Selective Serotonin Reuptake Inhibitors; Sertraline | 1997 |
Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes.
Topics: Animals; Excitatory Amino Acid Antagonists; Haloperidol; Hydrogen-Ion Concentration; Neuroprotective Agents; Nylidrin; Oocytes; Patch-Clamp Techniques; Piperidines; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1997 |
Multiple [3H]-nemonapride binding sites in calf brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Benzamides; Binding, Competitive; Brain; Cattle; Cerebellum; Cerebral Cortex; Corpus Striatum; Dioxanes; Dopamine Agonists; Dopamine Antagonists; Guanidines; Haloperidol; In Vitro Techniques; Isotope Labeling; Narcotic Antagonists; Pentazocine; Piperidines; Propylamines; Pyrrolidines; Receptors, Dopamine D2; Receptors, sigma; Sulpiride; Tritium | 1997 |
Differential modulation of NMDA-stimulated [3H]dopamine release from rat striatum by neuropeptide Y and sigma receptor ligands.
Topics: Analgesics; Animals; Corpus Striatum; Cyclohexylamines; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Haloperidol; Male; N-Methylaspartate; Neuropeptide Y; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1997 |
Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dioxoles; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Locomotion; Male; Mice; Piperidines; Receptors, AMPA | 1997 |
Disruption of latent inhibition in the rat by the 5-HT2 agonist DOI: effects of MDL 100,907, clozapine, risperidone and haloperidol.
Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Fluorobenzenes; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Reinforcement, Psychology; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
M100907, a selective 5-HT2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate-receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro.
Topics: Animals; Antipsychotic Agents; Clozapine; Fluorobenzenes; Haloperidol; Male; Patch-Clamp Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists | 1998 |
Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; Haloperidol; In Vitro Techniques; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1998 |
Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.
Topics: Acoustic Stimulation; Animals; Apomorphine; Clozapine; Dextroamphetamine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred Strains; Phencyclidine; Piperidines; Rats; Receptors, sigma; Reflex, Startle; Species Specificity | 1998 |
A novel computer-controlled conditioned avoidance apparatus for rats.
Topics: Amphetamines; Animals; Antipsychotic Agents; Avoidance Learning; Benzazepines; Clozapine; Computers; Cross-Over Studies; Dopamine Antagonists; Fluorobenzenes; Haloperidol; Male; Physical Conditioning, Animal; Piperidines; Raclopride; Rats; Rats, Sprague-Dawley; Salicylamides; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Modulation of the N-methyl-D-aspartate receptor by haloperidol: NR2B-specific interactions.
Topics: Amino Acid Sequence; Binding, Competitive; Chimera; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Mutagenesis, Site-Directed; Piperidines; Receptors, N-Methyl-D-Aspartate; Spermidine | 1998 |
M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice.
Topics: Animals; Antipsychotic Agents; Clozapine; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; In Vitro Techniques; Male; Patch-Clamp Techniques; Phencyclidine; Piperidines; Prefrontal Cortex; Pyramidal Cells; Raclopride; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Salicylamides; Serotonin Antagonists | 1998 |
Synthesis, in vitro binding, and tissue distribution of radioiodinated 2-[125I]N-(N-benzylpiperidin-4-yl)-2-iodo benzamide, 2-[125I]BP: a potential sigma receptor marker for human prostate tumors.
Topics: Animals; Benzamides; Binding, Competitive; Haloperidol; Humans; Indicators and Reagents; Iodine Radioisotopes; Kinetics; Male; Mice; Mice, Nude; Molecular Structure; Piperidines; Prostatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tissue Distribution; Tumor Cells, Cultured | 1998 |
Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Fluorobenzenes; Haloperidol; Male; Nucleus Accumbens; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors | 1998 |
An NR2B point mutation affecting haloperidol and CP101,606 sensitivity of single recombinant N-methyl-D-aspartate receptors.
Topics: Animals; Arginine; CHO Cells; Cricetinae; Dizocilpine Maleate; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Iodine Radioisotopes; Piperidines; Point Mutation; Receptors, N-Methyl-D-Aspartate | 1998 |
Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Carrier Proteins; Dopamine Antagonists; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Guinea Pigs; Haloperidol; Isoenzymes; Kinetics; Mice; Microsomes; Microsomes, Liver; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Tamoxifen; Tritium | 1998 |
[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses.
Topics: Acetylcholine; Animals; Autoradiography; Brain; Calibration; Carrier Proteins; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Female; Fluorine Radioisotopes; Haloperidol; Humans; Indans; Kinetics; Male; Membrane Transport Proteins; Mice; Organ Specificity; Piperidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synapses; Tissue Distribution; Tomography, Emission-Computed; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 1998 |
In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.
Topics: Adolescent; Adult; Aged; Child; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Isoenzymes; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Piperidines | 1998 |
Neuropharmacological assessment of potential dopamine D4 receptor-selective radioligands.
Topics: Aminopyridines; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Dopamine Agents; Dopamine Antagonists; Haloperidol; Humans; In Vitro Techniques; Ligands; Male; Piperidines; Prosencephalon; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4; Spiperone; Tritium | 1999 |
Synergistic interactions between ampakines and antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Catalepsy; Central Nervous System Stimulants; Dioxoles; Drug Synergism; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Haloperidol; Male; Methamphetamine; Motor Activity; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1999 |
Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist.
Topics: Animals; Binding, Competitive; Catalepsy; Cell Line; Dopamine Antagonists; Fluorobenzenes; Haloperidol; Humans; Indoles; Male; Piperidines; Quinolines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists | 1999 |
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists | 1999 |
Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo.
Topics: 3T3 Cells; Animals; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Dendrites; Fluorobenzenes; Haloperidol; Mianserin; Mice; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Risperidone; Ritanserin; Serotonin Antagonists; Transfection | 1999 |
Blockade of neurokinin3 receptors antagonizes drug-induced population response and depolarization block of midbrain dopamine neurons in guinea pigs.
Topics: Animals; Dopamine; Dopamine Antagonists; Electrophysiology; Guinea Pigs; Haloperidol; Male; Mesencephalon; Neurons; Piperidines; Receptors, Neurokinin-3 | 1999 |
Effects of NRA0045, NRA0160, and NRA0215 on regional Fos-like immunoreactivity in the rat brain.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Clozapine; Corpus Striatum; Haloperidol; Immunohistochemistry; Male; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Pyrrolidines; Rats; Rats, Wistar; Thiazoles | 1999 |
The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dopamine; Fluorobenzenes; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 2000 |
Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Catalepsy; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Haloperidol; Levodopa; Macaca mulatta; Male; Parkinson Disease, Secondary; Piperidines; Rats; Rats, Inbred F344; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2000 |
Sigma ligands inhibit the growth of small cell lung cancer cells.
Topics: Animals; Benzamides; Binding, Competitive; Carcinoma, Small Cell; Cell Division; Female; Guanidines; Haloperidol; Humans; Ligands; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Piperidines; Receptors, sigma; Tumor Cells, Cultured | 2000 |
Effects of oil intake in the conditioned place preference test in mice.
Topics: Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Conditioning, Psychological; Corn Oil; Dopamine Antagonists; Eating; Haloperidol; Indoles; Male; Mice; Piperidines; Receptors, Dopamine D1; Reward; Space Perception; Sulpiride | 2000 |
Separation and determination of haloperidol, parabens and some of their degradation products by micellar electrokinetic chromatography.
Topics: Benzoates; Calibration; Chromatography, Micellar Electrokinetic Capillary; Haloperidol; Parabens; Piperidines | 2000 |
Acute and repeated administration of the selective 5-HT(2A) receptor antagonist M100907 significantly alters the activity of midbrain dopamine neurons: an in vivo electrophysiological study.
Topics: Action Potentials; Animals; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluorobenzenes; Haloperidol; Injections, Intravenous; Male; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Substantia Nigra; Ventral Tegmental Area | 2001 |
Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Topics: Animals; Brain; Cell Line; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Kinetics; Mice; Mutation; Phenols; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Spermidine | 2001 |
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine | 2001 |
Antagonism at 5-HT(2A) receptors potentiates the effect of haloperidol in a conditioned avoidance response task in rats.
Topics: Animals; Avoidance Learning; Catalepsy; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Extrapyramidal Tracts; Fluorobenzenes; Haloperidol; Male; Piperidines; Raclopride; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists | 2001 |
NMDA receptor antagonists do not block the development of sensitization of catalepsy, but make its expression state-dependent.
Topics: Animals; Conditioning, Classical; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Male; Phenols; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate | 2001 |
Efficacy of antipsychotic agents at human 5-HT(1A) receptors determined by [3H]WAY100,635 binding affinity ratios: relationship to efficacy for G-protein activation.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Humans; Membranes; Piperazines; Piperidines; Pyridines; Pyrimidinones; Pyrrolidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Thiazoles; Thioridazine; Tritium | 2001 |
Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex.
Topics: Animals; Clozapine; Fluorobenzenes; Glutamic Acid; Haloperidol; Male; Microdialysis; Phencyclidine; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2001 |
A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Piperidines; Risperidone; Serotonin Antagonists | 2001 |
[Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies].
Topics: Aged; Donepezil; Drug Therapy, Combination; Hallucinations; Haloperidol; Humans; Indans; Lewy Body Disease; Male; Neuroleptic Malignant Syndrome; Nootropic Agents; Piperidines | 2001 |
Differential inhibition of T-type calcium channels by neuroleptics.
Topics: Antipsychotic Agents; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Line; Dose-Response Relationship, Drug; Flunarizine; Haloperidol; Humans; Ion Channel Gating; Kidney; Patch-Clamp Techniques; Penfluridol; Pimozide; Piperidines; Transfection | 2002 |
The effects of neuroleptics on the GABA-induced Cl- current in rat dorsal root ganglion neurons: differences between some neuroleptics.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Chloride Channel Agonists; Chloride Channels; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Haloperidol; Incidence; Membrane Potentials; Piperazines; Piperidines; Quetiapine Fumarate; Rats; Rats, Wistar; Seizures | 2002 |
Comparison of SSI with APCI as an interface of HPLC-mass spectrometry for analysis of a drug and its metabolites.
Topics: Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Haloperidol; Humans; Mass Spectrometry; Pharmaceutical Preparations; Piperidines; Ultrasonics | 2002 |
5-HT(1A) and 5-HT(2A) receptors minimally contribute to clozapine-induced acetylcholine release in rat medial prefrontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Clozapine; Corpus Striatum; Dopamine Antagonists; Fluorobenzenes; Haloperidol; Indophenol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2002 |
Muscarinic, adenosine A(2) and histamine H(3) receptor modulation of haloperidol-induced c-fos expression in the striatum and nucleus accumbens.
Topics: Animals; Cell Count; Cell Nucleus; Corpus Striatum; Dopamine Antagonists; Haloperidol; Histamine Antagonists; Male; Muscarinic Antagonists; Neurons; Nucleus Accumbens; Piperidines; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Receptors, Muscarinic; Receptors, Purinergic P1; Scopolamine; Tissue Distribution | 2002 |
Antipsychotic profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562) in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Thiazoles | 2002 |
5-HT(2A) receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner.
Topics: Animals; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Fluorobenzenes; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists | 2002 |
SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens.
Topics: Analysis of Variance; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Fluorobenzenes; Haloperidol; Male; Nucleus Accumbens; Phenols; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Telencephalon | 2002 |
In vitro and in vivo pharmacological profile of 4-(4-fluorobenzylidene)-1-[2-[5-(4-fluorophenyl)-1H-pyrazol-4-yl] ethyl] piperidine (NRA0161).
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Blood Pressure; Catalepsy; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperidines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Drug; Receptors, Serotonin; Risperidone; Stereotyped Behavior | 2002 |
Fully automated radioligand binding filtration assay for membrane-bound receptors.
Topics: Animals; Automation; Binding, Competitive; CHO Cells; Cricetinae; Filtration; Haloperidol; Indoles; Piperidines; Radioligand Assay; Receptors, Dopamine; Reproducibility of Results; Time Factors | 2002 |
Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glucose; Glutamates; Haloperidol; Neurons; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sodium Azide | 2002 |
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Dibenzothiazepines; Dopamine; Haloperidol; Isoxazoles; Male; Microdialysis; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 2002 |
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine | 2003 |
Effects of clozapine, haloperidol and iloperidone on neurotransmission and synaptic plasticity in prefrontal cortex and their accumulation in brain tissue: an in vitro study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Antipsychotic Agents; Brain Chemistry; Clozapine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Haloperidol; In Vitro Techniques; Isoxazoles; Magnesium; Male; Neuronal Plasticity; Patch-Clamp Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors | 2003 |
Influence of lipophilicity on the interactions of N-alkyl-4-phenyl-1,2,3,6-tetrahydropyridines and their positively charged N-alkyl-4-phenylpyridinium metabolites with cytochrome P450 2D6.
Topics: Catalysis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Haloperidol; Oxidation-Reduction; Piperidines; Pyridines; Pyridinium Compounds; Structure-Activity Relationship | 2003 |
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Camphanes; Cannabinoids; Carrageenan; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fibrosarcoma; Haloperidol; Hand Strength; Humerus; Hyperalgesia; Male; Mice; Mice, Inbred C3H; Morpholines; Myositis; Naphthalenes; Neoplasm Transplantation; Neoplasms; Pain; Piperidines; Psychomotor Performance; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Differential effects of iloperidone, clozapine, and haloperidol on working memory of rats in the delayed non-matching-to-position paradigm.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Choice Behavior; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Isoxazoles; Male; Memory, Short-Term; Muscarinic Antagonists; Nose; Piperidines; Rats; Reaction Time; Scopolamine; Time Factors | 2003 |
Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Chromatography, High Pressure Liquid; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Haloperidol; Male; Microdialysis; Motor Activity; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Stereotyped Behavior; Thiazoles; Time Factors | 2003 |
Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice.
Topics: Amino Acids; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluorobenzenes; Haloperidol; Hyperkinesis; Mice; Motor Activity; Piperidines; Receptors, Metabotropic Glutamate; Serotonin Antagonists; Time Factors; Xanthenes | 2003 |
Central nervous effects of neurolept-analgesia as induced by haloperidol and phenoperidine.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Electroencephalography; Haloperidol; Hypnotics and Sedatives; Pain Management; Phenoperidine; Piperidines | 1961 |
Problems in evaluation of R-1625.
Topics: Electroconvulsive Therapy; Haloperidol; Piperidines; Psychotherapy; Psychotic Disorders | 1959 |
[DRUGS ACTING ON THE NERVOUS SYSTEM. (2). WITH SPECIAL REFERENCE TO TRANQUILIZERS AND ANTIDEPRESSIVE AGENTS].
Topics: Amides; Amitriptyline; Antidepressive Agents; Benactyzine; Chemical Phenomena; Chemistry; Chlordiazepoxide; Desipramine; Diazepam; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Isocarboxazid; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nervous System; Nialamide; Pharmacology; Phenelzine; Piperidines; Tranquilizing Agents; Tranylcypromine; Tryptamines | 1963 |
[HUNTINGTON'S CHOREA, TEMPERAMENT DISORDERS OF MANIAC EXPRESSION. BENEFICIAL EFFECTS OF HALOPERIDOL (FLUORO-PHENYL-PIPERIDINE BUTYROPHENONE). ABSENCE OF THE THERAPEUTIC AKINETO-HYPERTONIC SYNDROME].
Topics: Bipolar Disorder; Butyrophenones; Chorea; Drug Therapy; Electromyography; Haloperidol; Humans; Huntington Disease; Mental Disorders; Movement Disorders; Piperidines; Psychotic Disorders; Temperament | 1964 |
ANALGESIA FOR SURGICAL PROCEDURES PERFORMED ON CONSCIOUS PATIENTS.
Topics: Analgesia; Anesthesia; Benperidol; Haloperidol; Humans; Narcotics; Piperidines; Stereotaxic Techniques; Tranquilizing Agents | 1965 |
[CLINICAL TRIAL OF A NEW NEUROLEPTIC IN LABOR. 4-(4-HYDROXY-4-PHENYL-PIPERIDINE)-BUTYROPHENONE].
Topics: Anesthesia; Anesthesia, Obstetrical; Antipsychotic Agents; Butyrophenones; Female; Haloperidol; Humans; Labor, Obstetric; Piperidines; Pregnancy | 1965 |
Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cyclopropanes; Dopamine; Dopamine Antagonists; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Microinjections; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 2003 |
Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens.
Topics: Animals; Cell Count; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Haloperidol; Immunohistochemistry; Nucleus Accumbens; Phenols; Piperidines; Proto-Oncogene Proteins c-fos; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species.
Topics: Animals; Azepines; Catalepsy; Clozapine; Drug Design; Haloperidol; Humans; In Vitro Techniques; Male; Mice; Piperidines; Quaternary Ammonium Compounds; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Dopamine D4; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship | 2004 |
Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluorobenzenes; Generalization, Stimulus; Haloperidol; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trihexyphenidyl | 2004 |
Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans.
Topics: Adult; Animals; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dogs; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Drug Interactions; Female; Haloperidol; Hepatocytes; Humans; Injections, Intravenous; Ketoconazole; Macaca fascicularis; Male; Metabolic Clearance Rate; Middle Aged; Piperidines; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfones | 2004 |
Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Catalepsy; Cell Count; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Ethylenediamines; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Haloperidol; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Piperidines; Prazosin; Prosencephalon; Proto-Oncogene Proteins c-fos; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors | 2004 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.
Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Grooming; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Piperidines; Schizophrenia | 2004 |
Effect of M2 muscarinic receptor blockade in rats with haloperidol-produced catatonic syndrome.
Topics: Animals; Catalepsy; Cyclopentanes; Diamines; Dopamine; Haloperidol; Male; Mandelic Acids; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M2; Syndrome; Trihexyphenidyl | 2004 |
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis.
Topics: Amphetamine; Amphetamines; Animals; Apomorphine; Behavior, Animal; Cues; Discrimination Learning; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Haloperidol; Indans; Injections, Intraperitoneal; Lysergic Acid Diethylamide; Male; Piperidines; Psychotic Disorders; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2005 |
Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo: role of 5-HT1A receptor activation.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Aripiprazole; Clozapine; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Agonists; Haloperidol; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Piperazines; Piperidines; Pyridines; Quinolones; Receptor, Serotonin, 5-HT1A; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Thiazoles | 2005 |
Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Binding, Competitive; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; DNA, Complementary; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Humans; Lisuride; Piperazines; Piperidines; Quinolones; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Risperidone; Transfection; Tritium | 2005 |
Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzofurans; Brain Chemistry; Cataplexy; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Synergism; Haloperidol; Histamine; Histamine Antagonists; Imidazoles; Ketoconazole; Male; Metabolic Clearance Rate; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Risperidone; Schizophrenia | 2005 |
The dopaminergic stabilizers (-)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Schizophrenic Psychology; Social Behavior | 2005 |
Effects of donepezil, nicotine and haloperidol on the central serotonergic system in mice: implications for Tourette's syndrome.
Topics: Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Donepezil; Dose-Response Relationship, Drug; Frontal Lobe; Gene Expression; Haloperidol; Humans; Indans; Ketanserin; Male; Mesencephalon; Mice; Mice, Inbred ICR; Nicotine; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Antagonists; Tourette Syndrome | 2005 |
Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples.
Topics: Animals; Antipsychotic Agents; Aprepitant; Benzodiazepines; Brain; Chromatography, High Pressure Liquid; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Evaluation, Preclinical; Fluorobenzenes; Gerbillinae; Haloperidol; Male; Mass Spectrometry; Morpholines; Neurokinin-1 Receptor Antagonists; Olanzapine; Piperidines; Raclopride; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Neurokinin-1; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrazoles | 2005 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine | 2005 |
Fyn is required for haloperidol-induced catalepsy in mice.
Topics: Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Blotting, Western; Calcium; Catalepsy; Cells, Cultured; Dopamine; Genotype; Haloperidol; Immunoblotting; Immunohistochemistry; Immunoprecipitation; In Situ Hybridization; Indoles; Mice; Neurons; Phosphorylation; Piperidines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors; Tyrosine | 2006 |
Sensitive determination of 4-(4-chlorophenyl)-4-hydroxypiperidine, a metabolite of haloperidol, in a rat biological sample by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Chromatography, High Pressure Liquid; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2006 |
Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Topics: Allosteric Regulation; Amantadine; Animals; Antipsychotic Agents; Dextrorphan; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Haloperidol; Male; Phenols; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride | 2006 |
The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor sid
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Dihydroxyphenylalanine; Dopamine Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Immunohistochemistry; Male; Motor Activity; Neostriatum; Nucleus Accumbens; Piperidines; Prolactin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine | 2006 |
[123I]TPCNE--a novel SPET tracer for the sigma-1 receptor: first human studies and in vivo haloperidol challenge.
Topics: Adult; Binding, Competitive; Brain; Dopamine Antagonists; Drug Interactions; Female; Gyrus Cinguli; Haloperidol; Humans; Iodine Radioisotopes; Liver; Male; Metabolic Clearance Rate; Middle Aged; Piperidines; Radioactive Tracers; Radioligand Assay; Receptors, sigma; Schizophrenia; Sigma-1 Receptor; Time Factors; Tomography, Emission-Computed, Single-Photon | 2006 |
Blockade of 5-HT2a receptors reduces haloperidol-induced attenuation of reward.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature Regulation; Clozapine; Differential Threshold; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Extinction, Psychological; Fluorobenzenes; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Serotonin 5-HT2 Receptor Antagonists | 2007 |
Antipsychotics improve Delta9-tetrahydrocannabinol-induced impairment of the prepulse inhibition of the startle reflex in mice.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Dopamine; Dronabinol; Haloperidol; Inhibition, Psychological; Male; Mice; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Pyrazoles; Reflex, Startle; Rimonabant; Risperidone; Rotarod Performance Test | 2006 |
Antipsychotic-like profile of thioperamide, a selective H3-receptor antagonist in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Dose-Response Relationship, Drug; Haloperidol; Histamine Agonists; Histamine Antagonists; Methylhistamines; Mice; Models, Animal; Motor Activity; Piperidines; Receptors, Histamine H3; Schizophrenia; Stereotyped Behavior; Time Factors | 2006 |
Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Sensitivity and Specificity; Spectrometry, Fluorescence | 2006 |
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Haloperidol; Head Movements; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperidines; Prolactin; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Urea | 2007 |
Synthesis and evaluation of novel radioiodinated benzamides for malignant melanoma.
Topics: Acetanilides; Animals; Benzamides; Binding, Competitive; Haloperidol; Iodine Radioisotopes; Isotope Labeling; Ligands; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Piperidines; Radioligand Assay; Radiopharmaceuticals; Receptors, sigma; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2007 |
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Biological Availability; Brain; Cell Line; Cytoskeletal Proteins; Drinking; Haloperidol; Humans; Ligands; Male; Motor Activity; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Social Behavior | 2007 |
In vivo characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino] cyclohexanol as a potential sigma-1 receptor imaging agent.
Topics: Animals; Autoradiography; Biotransformation; Brain; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Cyclohexanols; Haloperidol; Iodine Radioisotopes; Isotope Labeling; Male; Narcotic Antagonists; Nootropic Agents; Pentazocine; Piperazines; Piperidines; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Tissue Distribution | 2007 |
Videomicroscopic extraction of specific information on cell proliferation and migration in vitro.
Topics: Animals; Benzamides; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Glioma; Haloperidol; Humans; Image Processing, Computer-Assisted; Microscopy, Phase-Contrast; Microscopy, Video; Piperidines; Reproducibility of Results | 2008 |
Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats.
Topics: Aging; Animals; Antipsychotic Agents; Cells, Cultured; CHO Cells; Clozapine; Cricetinae; Cricetulus; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Dronabinol; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Male; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Rimonabant; Sex Characteristics; Signal Transduction | 2008 |
Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Benzamides; Central Nervous System Stimulants; Cognition; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nitroarginine; Piperidines; Rats; Rats, Wistar; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 2009 |
Delta-9-tetrahydrocannabinol differently affects striatal c-Fos expression following haloperidol or clozapine administration.
Topics: Animals; Antipsychotic Agents; Blotting, Western; Clozapine; Dronabinol; Gene Expression; Genes, fos; Haloperidol; Immunohistochemistry; Male; Neostriatum; Neurons; Piperidines; Psychotropic Drugs; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant | 2008 |
Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies.
Topics: Animals; Antipsychotic Agents; Binding Sites; Buffers; Ethanolamines; Haloperidol; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Oligopeptides; Oocytes; Piperidines; Protein Binding; Protein Refolding; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus | 2008 |
Effects of the dopamine stabilizer, OSU-6162, on brain stimulation reward and on quinpirole-induced changes in reward and locomotion.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Conditioning, Operant; Deep Brain Stimulation; Dopamine Agents; Haloperidol; Locomotion; Male; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors | 2009 |
Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Dopamine; Dopamine D2 Receptor Antagonists; Drug Synergism; Extracellular Space; Fluorobenzenes; Glutamic Acid; Haloperidol; Imidazoles; Indoles; Male; Microdialysis; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Antagonists | 2009 |
Endogenous nociceptin/orphanin FQ (N/OFQ) contributes to haloperidol-induced changes of nigral amino acid transmission and parkinsonism: a combined microdialysis and behavioral study in naïve and nociceptin/orphanin FQ receptor knockout mice.
Topics: Animals; Antipsychotic Agents; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Narcotic Antagonists; Neuropharmacology; Nociceptin; Nociceptin Receptor; Opioid Peptides; Parkinsonian Disorders; Piperidines; Receptors, Opioid; Substantia Nigra; Synaptic Transmission | 2010 |
Modulation of prepulse inhibition and stereotypies in rodents: no evidence for antipsychotic-like properties of histamine H3-receptor inverse agonists.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzofurans; Dizocilpine Maleate; Drug Inverse Agonism; Haloperidol; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Male; Methamphetamine; Mice; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stereotyped Behavior | 2010 |
Atypical antipsychotic properties of blonanserin, a novel dopamine D2 and 5-HT2A antagonist.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Male; Mice; Mice, Inbred Strains; Nucleus Accumbens; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Serotonin 5-HT2 Receptor Antagonists | 2010 |
p-Hydroxyamphetamine causes prepulse inhibition disruptions in mice: contribution of dopamine neurotransmission.
Topics: Animals; Benzazepines; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Oxidopamine; p-Hydroxyamphetamine; Piperazines; Piperidines; Pyridines; Pyrroles; Reflex, Startle; Salicylamides; Sensory Gating; Sympathomimetics; Synaptic Transmission | 2010 |
Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
Topics: Animals; Behavior, Animal; beta-Cyclodextrins; Brain-Derived Neurotrophic Factor; Cholesterol; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dronabinol; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agents; Haloperidol; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward | 2010 |
Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization.
Topics: Animals; Apomorphine; Aripiprazole; Buffers; Catalepsy; Cell Membrane; Cerebral Cortex; Corpus Striatum; Domperidone; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Antagonism; Drug Partial Agonism; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Hippocampus; Male; Piperazines; Piperidines; Pyridines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Stereotyped Behavior; Up-Regulation | 2011 |
Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence.
Topics: Alkaloids; Analysis of Variance; Animals; Apoptosis; Behavior, Animal; Benzodioxoles; Caspase 3; Colorimetry; Curcumin; Cytokines; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Haloperidol; Inflammation; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotransmitter Agents; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Wistar; Statistics as Topic; Thiobarbituric Acid Reactive Substances | 2011 |
Effects of 5-HT(2A) and 5-HT(2C) receptor antagonists on acute and chronic dyskinetic effects induced by haloperidol in rats.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Brain Chemistry; Catalepsy; Dyskinesia, Drug-Induced; Fluorobenzenes; Gene Expression Regulation; Haloperidol; Immunohistochemistry; In Situ Hybridization; Indoles; Ketanserin; Male; Mouth; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Antagonists | 2011 |
Effects of the dopamine stabilizers (S)-(-)-OSU6162 and ACR16 on prolactin secretion in drug-naive and monoamine-depleted rats.
Topics: Animals; Aripiprazole; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Hyperprolactinemia; Lactotrophs; Male; Methyltyrosines; Piperazines; Piperidines; Prolactin; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine | 2011 |
A ¹⁸F-labeled fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET Imaging of sigma₁ receptors.
Topics: Animals; Autoradiography; Brain; Female; Fluorine Radioisotopes; Haloperidol; Isotope Labeling; Mice; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, sigma; Spiro Compounds; Tissue Distribution | 2011 |
Influence of GIRK channel inhibition on alcohol abstinence and relapse risk in Japanese alcohol-dependent outpatients.
Topics: Alcoholism; Analysis of Variance; Asian People; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Haloperidol; Humans; Middle Aged; Outpatients; Paroxetine; Piperidines; Retrospective Studies; Risk; Secondary Prevention; Treatment Outcome | 2011 |
Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.
Topics: Acoustic Stimulation; Animals; Benzimidazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Imidazoles; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Narcotic Antagonists; Nociceptin Receptor; Photic Stimulation; Piperidines; Receptors, Dopamine; Receptors, Opioid; Reflex, Startle; Sensory Gating; Spiro Compounds | 2012 |
Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Drug Synergism; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Membrane Potentials; Olanzapine; Oxadiazoles; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Synaptic Transmission; Tetrahydronaphthalenes | 2012 |
Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.
Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Dronabinol; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tropanes | 2012 |
Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Brain; Catalepsy; Cells, Cultured; CHO Cells; Cricetinae; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Humans; Ligands; Locomotion; Male; Olanzapine; Piperidines; Prolactin; Pyridazines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine D2; Schizophrenia; Serotonin | 2012 |
Induction of glucose intolerance by acute administration of rimonabant.
Topics: Administration, Oral; Animals; Benzoxazines; Blood Glucose; Dopamine Antagonists; Eating; Fenclonine; Glucose; Glucose Intolerance; Haloperidol; Hepatocytes; Infusions, Intraventricular; Insulin; Male; Mice; Morpholines; Naphthalenes; Ondansetron; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Dopamine; Receptors, Serotonin; Rimonabant; Serotonin Antagonists | 2012 |
Prevention of the phencyclidine-induced impairment in novel object recognition in female rats by co-administration of lurasidone or tandospirone, a 5-HT(1A) partial agonist.
Topics: Animals; Cognition Disorders; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Isoindoles; Lurasidone Hydrochloride; Phencyclidine; Piperazines; Piperidines; Pyridines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Thiazoles; Urea | 2012 |
Angioedema occurring in patient prescribed iloperidone and haloperidol: a cross-sensitivity reaction to antipsychotics from different chemical classes.
Topics: Adult; Angioedema; Antipsychotic Agents; Drug Hypersensitivity; Haloperidol; Humans; Isoxazoles; Male; Piperidines | 2012 |
Structure-based drug design for dopamine D3 receptor.
Topics: Animals; Combinatorial Chemistry Techniques; Drug Design; Haloperidol; Humans; Indoles; Mice; Models, Molecular; Molecular Structure; Piperazines; Piperidines; Pyrazoles; Pyridines; Receptors, Dopamine D3; Spiperone; Structure-Activity Relationship; Sulpiride; Thiophenes | 2012 |
Delayed onset and prolonged interictal delirium following electroconvulsive therapy.
Topics: Cholinesterase Inhibitors; Delirium; Depressive Disorder; Donepezil; Electroconvulsive Therapy; Follow-Up Studies; Haloperidol; Humans; Hypnotics and Sedatives; Indans; Lorazepam; Male; Middle Aged; Piperidines; Risk Factors; Time Factors | 2012 |
Dopaminergic modulation of effort-related choice behavior as assessed by a progressive ratio chow feeding choice task: pharmacological studies and the role of individual differences.
Topics: 3,3'-Diaminobenzidine; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Choice Behavior; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Feeding Behavior; Haloperidol; Immunohistochemistry; Individuality; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Xanthines | 2012 |
The dopaminergic stabilizer pridopidine increases neuronal activity of pyramidal neurons in the prefrontal cortex.
Topics: Animals; Benzazepines; Chromans; Data Interpretation, Statistical; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiological Phenomena; Haloperidol; Injections, Intravenous; Male; Neurons; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2013 |
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes | 2014 |
Effect of olanzapine on scopolamine induced deficits in differential reinforcement of low rate 72s (DRL-72s) schedule in rats: involvement of the serotonergic receptors in restoring the deficits.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Cholinesterase Inhibitors; Conditioning, Operant; Donepezil; Haloperidol; Impulsive Behavior; Indans; Male; Muscarinic Antagonists; Olanzapine; Piperidines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reinforcement, Psychology; Scopolamine; Serotonin Antagonists; Sulfones | 2013 |
Anandamide attenuates haloperidol-induced vacuous chewing movements in rats.
Topics: Animals; Antipsychotic Agents; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Endocannabinoids; Haloperidol; Male; Mastication; Movement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Treatment Outcome | 2014 |
The involvement of sigma1 receptors in donepezil-induced rescue of hippocampal LTP impaired by beta-amyloid peptide.
Topics: Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Cholinesterase Inhibitors; Donepezil; Haloperidol; Indans; Long-Term Potentiation; Male; Morpholines; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, sigma | 2014 |
Examining dopamine D3 receptor occupancy by antipsychotic drugs via [3H]7-OH-DPAT ex vivo autoradiography and its cross-validation via c-fos immunohistochemistry in the rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dopamine Antagonists; Haloperidol; Indoles; Islands of Calleja; Male; Nitriles; Olanzapine; Piperidines; Proto-Oncogene Proteins c-fos; Radiography; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2014 |
Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standard-chow diets.
Topics: Analysis of Variance; Animals; Area Under Curve; Cannabinoid Receptor Antagonists; Choice Behavior; Conditioning, Operant; Delay Discounting; Diet, High-Fat; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Rimonabant | 2014 |
Combined serotonin (5-HT)1A agonism, 5-HT(2A) and dopamine D₂ receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Haloperidol; Isoindoles; Memory Disorders; Phencyclidine; Piperazines; Piperidines; Pyrimidines; Random Allocation; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Recognition, Psychology; Schizophrenia; Schizophrenic Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Urea | 2015 |
The serotonin 5-HT₁A receptor agonist tandospirone improves executive function in common marmosets.
Topics: Animals; Antipsychotic Agents; Callithrix; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Executive Function; Haloperidol; Isoindoles; Male; Piperazines; Piperidines; Psychological Tests; Psychotropic Drugs; Pyrimidines; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D1; Risperidone; Serotonin 5-HT1 Receptor Agonists | 2015 |
Neuropharmacology of light-induced locomotor activation.
Topics: Animals; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Haloperidol; Indoles; Ketamine; Light; Male; Motor Activity; Naphthyridines; Phencyclidine; Photic Stimulation; Piperazines; Piperidines; Pyridines; Quinpirole; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serotonin Antagonists | 2015 |
Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice.
Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Galantamine; Haloperidol; Hypokinesia; Indans; Male; Mice, Inbred Strains; Nootropic Agents; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Muscarinic; Serotonin Agents | 2015 |
Differential Pharmacological Regulation of Sensorimotor Gating Deficit in CB1 Knockout Mice and Associated Neurochemical and Histological Alterations.
Topics: Animals; Cannabinoid Receptor Antagonists; Central Nervous System Agents; Cerebral Cortex; Cholecystokinin; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Immunohistochemistry; Male; Methylphenidate; Mice, Knockout; Neurons; Parvalbumins; Peptide Fragments; Piperidines; Prepulse Inhibition; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-2; Risperidone; Time Factors | 2015 |
NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain; Catalepsy; Disease Models, Animal; Drug Interactions; Dyskinesia, Drug-Induced; Female; Haloperidol; Levodopa; Movement; Neurotransmitter Agents; Oxidopamine; Piperidines; Psychomotor Performance; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin Syndrome; Swimming; Vocalization, Animal | 2015 |
Atypical antipsychotic properties of AD-6048, a primary metabolite of blonanserin.
Topics: Animals; Antipsychotic Agents; Apomorphine; Basal Ganglia Diseases; Behavior, Animal; Catalepsy; Corpus Striatum; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Injections, Subcutaneous; Male; Mice; Nucleus Accumbens; Oncogene Proteins v-fos; Piperazines; Piperidines; Pyridines | 2015 |
Dopamine D3 receptor antagonism contributes to blonanserin-induced cortical dopamine and acetylcholine efflux and cognitive improvement.
Topics: Acetylcholine; Animals; Benzopyrans; Brain Chemistry; Cerebral Cortex; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Fluorenes; Haloperidol; Male; Mice; Mice, Inbred C57BL; Nootropic Agents; Oxazines; Phencyclidine; Piperazines; Piperidines; Rats, Long-Evans; Receptors, Dopamine D3 | 2015 |
Contribution of the central histaminergic transmission in the cataleptic and neuroleptic effects of haloperidol.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Chlorpheniramine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Histamine; Histamine Agonists; Histidine; Infusions, Intraventricular; Male; Piperidines; Ranitidine; Rats; Receptors, Histamine; Synaptic Transmission | 2015 |
Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes.
Topics: Cardiotoxicity; Cell Differentiation; Drug Discovery; Haloperidol; Human Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Myocytes, Cardiac; Piperidines; Pyridines; Quinidine | 2017 |
Serotonin 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Brain Waves; Cortical Synchronization; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Fluorobenzenes; Gamma Rhythm; Haloperidol; Hippocampus; Locomotion; Mice; Neural Pathways; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 2019 |
The type rather than the daily dose or number of antipsychotics affects the incidence of hyperglycemic progression.
Topics: Adult; Antipsychotic Agents; Clozapine; Dibenzothiepins; Female; Haloperidol; Humans; Hyperglycemia; Incidence; Japan; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Schizophrenia | 2022 |
Improved response to electroconvulsive therapy after switching from haloperidol to blonanserin in a patient with treatment-resistant schizophrenia.
Topics: Antipsychotic Agents; Electroconvulsive Therapy; Haloperidol; Humans; Piperazines; Piperidines; Schizophrenia; Schizophrenia, Treatment-Resistant | 2022 |
Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Hypoxia; Ligands; Nomifensine; Ouabain; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2022 |
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands.
Topics: Haloperidol; Ligands; Piperidines; Quinolines; Receptors, sigma; Structure-Activity Relationship | 2022 |
Diphenylprolinol silyl ether as a catalyst in an enantioselective, catalytic, formal aza [3+3] cycloaddition reaction for the formation of enantioenriched piperidines.
Topics: Aldehydes; Aza Compounds; Carbamates; Catalysis; Cyclization; Ethers; Molecular Structure; Piperidines; Proline; Stereoisomerism | 2008 |