haloperidol and paroxetine

haloperidol has been researched along with paroxetine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.44)18.7374
1990's11 (26.83)18.2507
2000's17 (41.46)29.6817
2010's12 (29.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goodman, MM; Kabalka, GW; Kung, HF; Kung, MP; Switzer, R1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Dalvie, D; Loi, CM; Smith, DA1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Cooper, SM; Jackson, D; Loudon, JM; McClelland, GR; Raptopoulos, P1
Bruun, RD; Budman, CL; Sherling, M1
Bergeron, R; De Montigny, C; Debonnel, G1
Copolov, D; Dean, B; Hill, C; Keks, N; Naylor, L; Opeskin, K; Pavey, G1
König, F; Löble, M; Wolfersdorf, M1
Earley, B; Faherty, CJ; Leonard, BE1
Bøgesø, KP; Dannals, RF; Hatzidimitriou, G; Ravert, HT; Ricaurte, GA; Scheffel, UA; Suehiro, M; Wagner, HN1
Christenson, GA; Keuthen, NJ; Mansueto, CS; O'Sullivan, RL; Stein, DJ; Swedo, SE1
Colado, MI; Esteban, B; Granados, R; Green, AR; Martín, AB; O'Shea, E1
Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J1
Bottlender, R; Möller, HJ1
Bell, R; Campbell, C; Green, JF; King, DJ; McCartan, D; Pickering, A; Trimble, K1
Rehavi, M; Roz, N; Weizman, A1
König, F; Raape, J; Truöl, S; Von Hippel, C1
Gaisler-Salomon, I; Green, A; Joel, D; Schiller, D; Weiner, I1
Bonikovski, V; Futuro-Neto, HA; Pires, JG1
de Bruijn, ER; Hulstijn, W; Ruigt, GS; Sabbe, BG; Verkes, RJ1
Hulstijn, W; Morrens, M; Ruigt, GS; Sabbe, BG; Verkes, RJ; Wezenberg, E1
Alfirevic, Z; Degoricija, V; Vucicevic, Z; Vukicevic-Badouin, D1
Hasegawa, R; Ikeda, K; Karasawa, J; Tamura, K; Yamamoto, H; Yamamoto, T; Yasumoto, S1
Asukai, N; Haraguchi, A; Hori, T; Ikeda, K; Ogai, Y; Senoo, E1
Gurwitz, D; Morag, A; Oved, K1

Reviews

1 review(s) available for haloperidol and paroxetine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for haloperidol and paroxetine

ArticleYear
The psychomotor effects of paroxetine alone and in combination with haloperidol, amylobarbitone, oxazepam, or alcohol.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 350

    Topics: Adult; Amobarbital; Antidepressive Agents; Arousal; Double-Blind Method; Ethanol; Female; Haloperidol; Humans; Male; Middle Aged; Oxazepam; Paroxetine; Piperidines; Psychomotor Performance; Randomized Controlled Trials as Topic; Reaction Time; Serotonin Antagonists

1989
The differential effects of chlorpromazine and haloperidol on latent inhibition in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:2

    Topics: Acoustic Stimulation; Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Attention; Chlorpromazine; Cognition; Double-Blind Method; Haloperidol; Humans; Learning; Lorazepam; Male; Neuropsychological Tests; Paroxetine; Psychomotor Performance; Space Perception

2001
Effects of antipsychotic and antidepressant drugs on action monitoring in healthy volunteers.
    Brain research, 2006, Aug-11, Volume: 1105, Issue:1

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Brain Mapping; Contingent Negative Variation; Double-Blind Method; Electroencephalography; Female; Haloperidol; Humans; Linear Models; Male; Monitoring, Physiologic; Olanzapine; Paroxetine; Reaction Time

2006
Psychomotor and memory effects of haloperidol, olanzapine, and paroxetine in healthy subjects after short-term administration.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Memory; Olanzapine; Paroxetine; Psychomotor Performance; Reference Values

2007

Other Studies

36 other study(ies) available for haloperidol and paroxetine

ArticleYear
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
    Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tropanes

1994
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Combined pharmacotherapy risk.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:3

    Topics: Child; Drug Therapy, Combination; Haloperidol; Humans; Male; Obsessive-Compulsive Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors; Tourette Syndrome

1995
Modification of the N-methyl-D-aspartate response by antidepressant sigma receptor ligands.
    European journal of pharmacology, 1993, Aug-24, Volume: 240, Issue:2-3

    Topics: 1-Naphthylamine; Animals; Antidepressive Agents; Clorgyline; Electrophysiology; Haloperidol; Male; N-Methylaspartate; Paroxetine; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sertraline; Tranylcypromine

1993
Changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3H]paroxetine.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Binding, Competitive; Carrier Proteins; Female; Haloperidol; Hippocampus; Humans; Male; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Suicide; Tritium

1996
[Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis].
    Der Nervenarzt, 1996, Volume: 67, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzamides; Depressive Disorder; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuroleptic Malignant Syndrome; Neurologic Examination; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Syndrome; Trimipramine

1996
Behavioural effects of selective serotonin reuptake inhibitors following direct micro injection into the left red nucleus of the rat.
    Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:1

    Topics: 1-Naphthylamine; Animals; Behavior, Animal; Chlorpromazine; Citalopram; Fluoxetine; Fluvoxamine; Guanidines; Haloperidol; Male; Microinjections; Motor Activity; Paroxetine; Piperidines; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Selective Serotonin Reuptake Inhibitors; Sertraline

1997
Highly potent indanamine serotonin uptake blockers as radiotracers for imaging serotonin uptake sites.
    Nuclear medicine and biology, 1994, Volume: 21, Issue:8

    Topics: Animals; Autoradiography; Brain; Haloperidol; Indans; Mice; Paroxetine; Radiopharmaceuticals; Rats; Selective Serotonin Reuptake Inhibitors; Tissue Distribution

1994
Trichotillomania: behavioral symptom or clinical syndrome?
    The American journal of psychiatry, 1997, Volume: 154, Issue:10

    Topics: Adult; Behavior Therapy; Combined Modality Therapy; Female; Haloperidol; Humans; Paroxetine; Trichotillomania

1997
Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Animals; Body Temperature; Brain; Dopamine; Free Radicals; Haloperidol; Levodopa; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurodegenerative Diseases; Paroxetine; Rats; Serotonin

1999
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.
    Journal of neuroendocrinology, 1999, Volume: 11, Issue:11

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium

1999
Negative symptoms due to sleep apnea syndrome in a patient with a delusional disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Antimanic Agents; Antipsychotic Agents; Delusions; Haloperidol; Humans; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Risperidone; Severity of Illness Index; Sleep Apnea Syndromes

1999
Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:3

    Topics: Animals; Antipsychotic Agents; Binding Sites; Biological Transport; Brain; Brain Chemistry; Clozapine; Drug Administration Schedule; Fluoxetine; Haloperidol; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neuropeptides; Paroxetine; Piperazines; Rats; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2002
[Improvement of tardive dyskinesia after treatment with olanzapine].
    Psychiatrische Praxis, 2002, Volume: 29, Issue:6

    Topics: Affective Disorders, Psychotic; Aged; Benzodiazepines; Depressive Disorder, Major; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Neurologic Examination; Olanzapine; Paroxetine; Patient Admission; Pirenzepine

2002
A comparison of drug effects in latent inhibition and the forced swim test differentiates between the typical antipsychotic haloperidol, the atypical antipsychotics clozapine and olanzapine, and the antidepressants imipramine and paroxetine.
    Behavioural pharmacology, 2003, Volume: 14, Issue:3

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Clozapine; Conditioning, Psychological; Haloperidol; Imipramine; Inhibition, Psychological; Male; Models, Animal; Olanzapine; Paroxetine; Pirenzepine; Rats; Rats, Wistar; Swimming

2003
Acute effects of selective serotonin reuptake inhibitors on neuroleptic-induced catalepsy in mice.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2005, Volume: 38, Issue:12

    Topics: Animals; Anti-Dyskinesia Agents; Catalepsy; Disease Models, Animal; Female; Fluoxetine; Haloperidol; Male; Mice; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Factors; Time Factors

2005
Fatal hyponatremia and other metabolic disturbances associated with psychotropic drug polypharmacy.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:5

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain Edema; Fatal Outcome; Fluphenazine; Haloperidol; Heart Arrest; Humans; Hyperglycemia; Hyponatremia; Inappropriate ADH Syndrome; Male; Mental Disorders; Olanzapine; Pancreatitis; Paroxetine; Polypharmacy; Selective Serotonin Reuptake Inhibitors

2007
Inhibitory effect of selective serotonin reuptake inhibitors on the vesicular monoamine transporter 2.
    Neuroscience letters, 2009, May-01, Volume: 454, Issue:3

    Topics: Animals; Dopamine; Fluoxetine; Fluvoxamine; Haloperidol; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Wistar; Reserpine; Selective Serotonin Reuptake Inhibitors; Synaptic Vesicles; Vesicular Monoamine Transport Proteins

2009
Influence of GIRK channel inhibition on alcohol abstinence and relapse risk in Japanese alcohol-dependent outpatients.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2011, Volume: 31, Issue:2

    Topics: Alcoholism; Analysis of Variance; Asian People; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Haloperidol; Humans; Middle Aged; Outpatients; Paroxetine; Piperidines; Retrospective Studies; Risk; Secondary Prevention; Treatment Outcome

2011
Sex differences in human lymphoblastoid cells sensitivities to antipsychotic drugs.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:3

    Topics: Anti-Inflammatory Agents; Antidepressive Agents; Antineoplastic Agents; Antipsychotic Agents; Cell Division; Cell Survival; Cells, Cultured; Cytostatic Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Resistance; Dystonic Disorders; Female; Haloperidol; Humans; Lymphocytes; Male; Paroxetine; Risperidone; Schizophrenia; Sex Characteristics; Sex Distribution

2013