Compounds > haloperidol

haloperidol and osu 6162

haloperidol has been researched along with osu 6162 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlsson, A; Hansson, L; Lin, CH; Smith, MW; Sonesson, C; Svensson, K; Waters, N; Wikström, H1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW1
Pettersson, F; Pontén, H; Sonesson, C; Waters, N; Waters, S1
Carlsson, A; Carlsson, ML; Markinhuhta, KR; Rung, JP1
Barlow, KB; Johansson, AM; Kapur, S; Natesan, S; Nobrega, JN; Reckless, GE; Svensson, KA1
Benaliouad, F; Kapur, S; Natesan, S; Rompré, PP1
Carlsson, A; Carlsson, ML; Johansson, AM; Rung, E; Rung, JP; Svensson, K1

Other Studies

7 other study(ies) available for haloperidol and osu 6162

ArticleYear
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Animals; Benzazepines; Brain; CHO Cells; Cricetinae; Dihydroxyphenylalanine; Dopamine D2 Receptor Antagonists; Habituation, Psychophysiologic; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Motor Activity; Optical Rotation; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; Reserpine; Serotonin Antagonists; Spiperone; Structure-Activity Relationship; Transfection

1994
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results

2006
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Cell Line; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Ligands; Male; Models, Chemical; Molecular Structure; Motor Activity; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2

2010
The dopaminergic stabilizers (-)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:5

    Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Schizophrenic Psychology; Social Behavior

2005
The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor sid
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Dihydroxyphenylalanine; Dopamine Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Immunohistochemistry; Male; Motor Activity; Neostriatum; Nucleus Accumbens; Piperidines; Prolactin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine

2006
Effects of the dopamine stabilizer, OSU-6162, on brain stimulation reward and on quinpirole-induced changes in reward and locomotion.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:6

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Conditioning, Operant; Deep Brain Stimulation; Dopamine Agents; Haloperidol; Locomotion; Male; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors

2009
Effects of the dopamine stabilizers (S)-(-)-OSU6162 and ACR16 on prolactin secretion in drug-naive and monoamine-depleted rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1

    Topics: Animals; Aripiprazole; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Hyperprolactinemia; Lactotrophs; Male; Methyltyrosines; Piperazines; Piperidines; Prolactin; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine

2011