haloperidol has been researched along with norclozapine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Dorsey, J; Katz, T; Lawlor, E; Messer, WS; Nagy, PI; Rieman, M; Tejada, FR; Warrier, M; Wu, C; Xu, M | 1 |
| Jia, L; Sun, H | 1 |
| Giordanetto, F; Leach, AG; Zachariae, U | 1 |
| Sen, S; Sinha, N | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Albus, KE; Frazier, JA; Gordon, CT; Grothe, DR; McKenna, K; Piscitelli, SC; Rapoport, JL | 1 |
| Chang, WH; Jann, MW; Lin, SK; Liu, HC; Wei, FC | 1 |
| Hietala, J; Korpi, ER; Kuoppamäki, M; Lüddens, H; Syvälahti, E; Wong, G | 1 |
| Homayoun, H; Moghaddam, B | 1 |
| Barlow, KB; Kapur, S; Natesan, S; Nobrega, JN; Reckless, GE | 1 |
| Axelsson, S; Eriksson, AC; Hägg, S; Lindahl, TL; Whiss, PA | 1 |
| Bourguignon, JJ; Carnicella, S; Mongeot, A; Oberling, P | 1 |
| Meltzer, HY; Porter, JH; Vunck, SA; Wiebelhaus, JM | 1 |
1 trial(s) available for haloperidol and norclozapine
| Article | Year |
|---|---|
Plasma clozapine and haloperidol concentrations in adolescents with childhood-onset schizophrenia: association with response.
Topics: Adolescent; Age of Onset; Child; Clozapine; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenia, Childhood; Schizophrenic Psychology; Treatment Outcome | 1994 |
15 other study(ies) available for haloperidol and norclozapine
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Design and synthesis of novel derivatives of the muscarinic agonist tetra(ethylene glycol)(3-methoxy-1,2,5-thiadiazol-4-yl) [3-(1-methyl-1,2,5,6-tetrahydropyrid-3-yl)-1,2,5-thiadiazol-4-yl] ether (CDD-0304): effects of structural modifications on the bind
Topics: Animals; Antipsychotic Agents; Cell Line; Cyclic AMP; Drug Design; Humans; Hydrolysis; Ligands; Mice; Models, Molecular; Muscarinic Agonists; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositols; Piperidines; Radioligand Assay; Receptors, Muscarinic; Recombinant Fusion Proteins; Structure-Activity Relationship; Thiadiazoles | 2006 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Monitoring of plasma clozapine levels and its metabolites in refractory schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Female; Haloperidol; Humans; Male; Schizophrenia | 1996 |
Effects of clozapine metabolites and chronic clozapine treatment on rat brain GABAA receptors.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Drug Evaluation, Preclinical; GABA Antagonists; GABA-A Receptor Antagonists; Haloperidol; In Vitro Techniques; Logistic Models; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Fine-tuning of awake prefrontal cortex neurons by clozapine: comparison with haloperidol and N-desmethylclozapine.
Topics: Action Potentials; Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Male; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Wakefulness | 2007 |
Evaluation of N-desmethylclozapine as a potential antipsychotic--preclinical studies.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Avoidance Learning; Biomarkers; Brain; Brain Chemistry; Catalepsy; Clozapine; Dopamine Agonists; Drug Evaluation, Preclinical; Haloperidol; Male; Piperazines; Prolactin; Proto-Oncogene Proteins c-fos; Psychotic Disorders; Quinolones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Treatment Outcome | 2007 |
In vitro effects of antipsychotics on human platelet adhesion and aggregation and plasma coagulation.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Coagulation; Blood Platelets; Clozapine; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Olanzapine; Partial Thromboplastin Time; Platelet Adhesiveness; Platelet Aggregation; Prothrombin Time; Risperidone; Thromboembolism; Venous Thrombosis | 2007 |
Prefrontal cortex and reversion of atropine-induced disruption of the degraded contingency effect by antipsychotic agents and N-desmethylclozapine in rats.
Topics: Animals; Antipsychotic Agents; Atropine; Benzodiazepines; Clozapine; Conditioning, Classical; Drug Interactions; Haloperidol; Male; Muscarinic Antagonists; Olanzapine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2010 |
Discriminative stimulus properties of N-desmethylclozapine, the major active metabolite of the atypical antipsychotic clozapine, in C57BL/6 mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Mice; Mice, Inbred C57BL; Piperazines; Quinolones | 2012 |