haloperidol has been researched along with neurotensin in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (21.60) | 18.7374 |
| 1990's | 59 (47.20) | 18.2507 |
| 2000's | 30 (24.00) | 29.6817 |
| 2010's | 9 (7.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Dix, TA; Hadden, MK; Lassetter, MR; Orwig, KS | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Bissette, G; Levant, B; Myers, B; Nemeroff, CB | 1 |
| Dobie, DJ; Dorsa, DM; Merchant, KM | 1 |
| Blaha, CD; Phillips, AG | 1 |
| Dobie, DJ; Dorsa, DM; Merchant, KM; Raskind, MA | 1 |
| Dobner, PR; Dorsa, DM; Merchant, KM | 1 |
| Zahm, DS | 1 |
| Levant, B; Nemeroff, CB | 1 |
| Marsden, CA; Rivest, R | 1 |
| Baldessarini, RJ; Bissette, G; Campbell, A; Kilts, CD; Levant, B; Nemeroff, CB | 1 |
| Bissette, G; Levant, B; Nemeroff, CB; Widerlöv, E | 1 |
| Jolicoeur, FB; Marsden, CA; Rivest, R | 1 |
| Bissette, G; Davis, MD; Heffner, TG; Levant, B; Nemeroff, CB | 1 |
| Campbell, AD; Erwin, VG; Jones, BC | 1 |
| Balaban, C; Kauffman, G; Seaton, J; Washington, J; Xing, LP | 1 |
| Hernandez, DE; Jennes, L | 1 |
| Amato, G; Calzà, L; Giardino, L; Piazza, PV; Zanni, M | 1 |
| Bunney, BS; Shi, WS | 1 |
| Bissette, G; Garver, DL; Nemeroff, CB; Yao, JK | 1 |
| Ashleigh, EA; Dorsa, DM; Merchant, KM; Miller, MA | 1 |
| Ford, AP; Marsden, CA | 1 |
| Beitz, AJ; Murtaugh, MP; Williams, FG | 1 |
| Barrett, JE; Brady, LS | 1 |
| Maigret, C; Van Wimersma Greidanus, TB | 1 |
| Bissette, G; Dauer, WT; Kilts, CD; Nemeroff, CB; O'Connor, L | 1 |
| Bush, LG; Gibb, JW; Hanson, GR; Merchant, KM | 1 |
| Berry, SA; Gudelsky, GA; Meltzer, HY | 1 |
| Beinfeld, MC; Bissette, G; Fibiger, HC; MacLennan, AJ; Nemeroff, CB; Radke, JM; Vincent, SR | 1 |
| Bissette, G; Levant, B; Nemeroff, CB | 1 |
| Colbern, DL; Twombly, DA | 1 |
| Arissen, SM; de Bruijckere, LM; de Koning, EJ; Donker, DK; Hulshof, RL; Pabst, PH; Ruesink, RW; van Berckel, BN; van de Brug, F; van Wimersma Greidanus, TB | 1 |
| Hernandez, DE; Melvin, JA; Prange, AJ; Stanley, DA | 1 |
| Furukawa, T; Shibata, K; Yamada, K | 1 |
| Krechting, B; Maigret, C; Van Wimersma Greidanus, TB | 1 |
| Colbern, DL; Maigret, C; Spruijt, BM; Ten Haaf, JA; van Wimersma Greidanus, TB | 1 |
| Henke, PG; Ray, A; Sullivan, RM | 1 |
| Eggerman, KW; Zahm, DS | 1 |
| Anderson, CM; Bissette, G; Ely, TD; Kilts, CD; Nemeroff, CB | 1 |
| Culling-Berglund, A; Davis, TP | 1 |
| Colbern, DL; Van Wimersma Greidanus, TJ; Van Zinnicq Bergmann, FF | 1 |
| Kalivas, PW | 1 |
| Simasko, SM; Weiland, GA | 1 |
| Nemeroff, CB | 1 |
| Costa, E; Govoni, S; Hong, JS; Yang, HY | 1 |
| Hernandez, DE; Nemeroff, CB; Orlando, RC; Prange, AJ | 1 |
| Burgess, SK; Kalivas, PW; Nemeroff, CB; Prange, AJ | 1 |
| Bissette, G; Breese, GR; Manberg, PJ; Nemeroff, CB; Osbahr, AJ; Prange, AJ | 1 |
| Birkemo, LS; Ervin, GN; Nemeroff, CB; Prange, AJ | 1 |
| Freedman, R; Hoffer, B; Marwaha, J | 1 |
| Bissette, G; Breslin, NA; Lowrimore, P; Nemeroff, CB; Suddath, RL; Weinberger, DR | 1 |
| Castel, MN; Dagerlind, A; Hökfelt, T; Morino, P | 1 |
| Fibiger, HC; Ikemoto, K; Maeda, T; Satoh, K | 1 |
| Kinkead, B; Nemeroff, CB; Owens, MJ | 2 |
| Diaz, J; Dimitriadou, V; Griffon, N; Lammers, CH; Levesque, D; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P | 1 |
| Gross, R; Kilts, CD; Lambert, PD; Nemeroff, CB | 1 |
| Bedard, A; Robertson, GS; St-Jean, M; Tetzlaff, W; Wigle, N | 1 |
| Keane, PE; Labie, C; Le Fur, G; Saubusse, P; Soubrié, P | 1 |
| Merchant, KM | 1 |
| Davis, TP; Konkoy, CS; Waters, SM | 1 |
| Gibb, JW; Gygi, SP; Hanson, GR | 1 |
| Merchant, KM; Miller, MA | 1 |
| Kinkead, B; Nemeroff, CB | 1 |
| Aravagiri, M; Dobie, DJ; Dorsa, DM; Filloux, FM; Merchant, KM; Totzke, M | 1 |
| Diaz, J; Griffon, N; Lammers, CH; Lévesque, D; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
| Banks, B; Bissette, G; Clement, R; Griff, D; Kitabgi, P; Nemeroff, C | 1 |
| Keane, PE; Labie, C; Le Fur, G; Soubrié, P | 1 |
| Dorsa, DM; Merchant, KM | 1 |
| Dorsa, DM; Hanson, GR; Merchant, KM | 1 |
| Dobie, DJ; Dorsa, DM; Dysken, MW; Hamblin, MW; Merchant, KM; Vatassery, GT | 1 |
| Bouchard, P; Dumont, Y; Fournier, A; Quirion, R; St-Pierre, S | 1 |
| Decker, KP; Merchant, KM; Roy-Byrne, PP | 1 |
| Aravagiri, M; Lynch, AM; Nemeroff, CB; Owens, MJ; See, RE | 1 |
| Brog, JS; Zahm, DS | 1 |
| Krause, JE; Poulad, D; Williams, ES; Zahm, DS | 1 |
| Bush, LG; Davis, K; Gibb, JW; Hanson, GR; Schmidt, CJ; Taylor, VL | 1 |
| Augood, SJ; Emson, PC; Westmore, K | 1 |
| Adams, MR; Dobie, DJ; Dorsa, DM; Merchant, KM; Unis, A | 1 |
| Shearman, LP; Weaver, DR | 1 |
| Hanson, GR; Huang, W | 1 |
| Adams, MR; Brandon, EP; Chartoff, EH; Dorsa, DM; Idzerda, RL; McKnight, GS | 1 |
| Cheung, S; Hentschel, K; Lookingland, KJ; Moore, KE | 1 |
| Krause, JE; Williams, ES; Zahm, DS | 1 |
| Nemeroff, CB; Owens, MJ; Radke, JM; Ritchie, JC | 1 |
| Grosu, DS; Krause, JE; Welch, MA; Williams, ES; Zahm, DS | 1 |
| Feldpaush, DL; Meng, ZH; Merchant, KM | 1 |
| Garimelli, B; Levant, B; Merchant, KM; Shafer, RA | 1 |
| Chartoff, EH; Dorsa, DM; Ward, RP | 1 |
| Boules, M; Cusack, B; Fauq, A; McCormick, DJ; Richelson, E; Tyler, BM | 1 |
| Beaudry, G; Langlois, MC; Lévesque, D; Rouillard, C; Weppe, I | 1 |
| Accili, D; Betancur, C; Cazillis, M; Fuchs, S; Lépée-Lorgeoux, I; Rostène, W | 1 |
| Binder, EB; Kilts, CD; Kinkead, B; Nemeroff, CB; Owens, MJ | 1 |
| Brun, P; Leonetti, M; Renaud, B; Sotty, F; Soubrié, P; Steinberg, R; Suaud-Chagny, MF | 1 |
| Carraway, RE; Deitemeyer, N; Deutch, AY; Dobner, PR; Fadel, J | 1 |
| Deitrich, RA; Erwin, VG; Radcliffe, R | 1 |
| Boules, M; Fauq, A; Jackson, J; McCormick, D; McMahon, B; Richelson, E; Stewart, J; Warrington, L | 1 |
| Gruber, SH; Mathé, AA; Nomikos, GG | 2 |
| Arnt, J; Hertel, P; Olsen, CK | 1 |
| Arrang, JM; Héron, A; Ortiz, J; Pillot, C; Ridray, S; Schwartz, JC | 1 |
| Khaing, ZZ; Lerman, DN; Lipska, BK; Weickert, CS; Weinberger, DR | 1 |
| Boules, M; Fauq, A; McCormick, D; McMahon, B; Richelson, E; Stewart, J; Wang, R; Warrington, L; Yerbury, S | 1 |
| Betancur, C; Giros, B; Hamon, M; Roubert, C; Soubrié, P; Spielewoy, C | 1 |
| Feifel, D; Melendez, G; Shilling, PD | 1 |
| Arvanitis, L; Bauer, D; Meltzer, HY; Rein, W | 1 |
| Chartoff, EH; Dorsa, DM; Palmiter, RD; Szczypka, MS | 1 |
| López Ordieres, MG; Rodríguez de Lores Arnaiz, G | 1 |
| Deitemeyer, N; Dobner, PR; Egnatashvili, V; Kinkead, B; Murray, T; Nemeroff, CB | 1 |
| Dix, TA; Hadden, MK; Kokko, KP; Mazella, J; Orwig, KS | 1 |
| Cohen, BM; Ma, J; Ye, N | 1 |
| Geisler, S; Zahm, DS | 1 |
| Chen, L; Cui, QL; Xie, JX; Xue, Y; Yung, WH | 1 |
| Feifel, D; Melendez, G; Priebe, K; Shilling, PD | 1 |
| Dai, J; Huang, M; Li, Z; Meltzer, HY; Prus, AJ | 1 |
| Kinkead, B; Nemeroff, CB; Owens, MJ; Yan, F | 1 |
| Boules, M; Briody, S; Fauq, I; Oliveros, A; Richelson, E | 1 |
| Chen, L; Xue, Y | 1 |
| Ebrecht, B; Holly, EN; Prus, AJ | 1 |
| Hillhouse, TM; LaCrosse, AL; Prus, AJ | 1 |
| Bédard, AM; Bouchard, C; Lévesque, D; Minogianis, EA; Rompré, PP; Samaha, AN; Servonnet, A | 1 |
3 review(s) available for haloperidol and neurotensin
| Article | Year |
|---|---|
Expression of the proneurotensin gene in the rat brain and its regulation by antipsychotic drugs.
Topics: Aging; Animals; Antipsychotic Agents; Brain; Caudate Nucleus; Cyclic AMP Response Element-Binding Protein; Gene Expression; Haloperidol; Neurotensin; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Putamen; Rats; Receptors, Dopamine; RNA, Messenger; Transcription, Genetic | 1992 |
Anatomy and mechanisms of neurotensin-dopamine interactions in the central nervous system.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Cyclic AMP; Dopamine; Haloperidol; Neurotensin; Pyrazoles; Quinolines; Receptors, Dopamine; Receptors, Neurotensin; Schizophrenia; Signal Transduction | 1995 |
The effects of typical and atypical antipsychotic drugs on neurotensin-containing neurons in the central nervous system.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Haloperidol; Humans; Neurotensin; Nucleus Accumbens; Rats; Receptors, Neurotensin; Schizophrenia | 1994 |
1 trial(s) available for haloperidol and neurotensin
| Article | Year |
|---|---|
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cannabinoids; Double-Blind Method; Drugs, Investigational; Female; Haloperidol; Humans; Male; Middle Aged; Neurotensin; Peptide Fragments; Piperidines; Placebos; Psychotic Disorders; Pyrazoles; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-3; Research Design; Rimonabant; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome | 2004 |
121 other study(ies) available for haloperidol and neurotensin
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy.
Topics: Aminopeptidases; Animals; Binding, Competitive; Body Temperature; Calcium; Cell Line; Humans; In Vitro Techniques; Intracellular Space; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Structure-Activity Relationship | 2009 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Pharmacological specificity of the increase in neurotensin concentrations after antipsychotic drug treatment.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Chlordiazepoxide; Desipramine; Diphenhydramine; Haloperidol; Male; Neurotensin; Rats; Rats, Inbred Strains | 1992 |
Pharmacological evidence for common mechanisms underlying the effects of neurotensin and neuroleptics on in vivo dopamine efflux in the rat nucleus accumbens.
Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Electrochemistry; Haloperidol; Kinetics; Male; Neurotensin; Nucleus Accumbens; Rats; Tetrodotoxin | 1992 |
Neurotensin mRNA expression in response to haloperidol is decreased in the dorsolateral striatum of aged rats.
Topics: Aging; Animals; Corpus Striatum; Gene Expression; Haloperidol; Male; Neurotensin; Peptide Fragments; Rats; RNA, Messenger | 1992 |
Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum.
Topics: Animals; Autoradiography; Cloning, Molecular; Clozapine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Male; Models, Genetic; Models, Neurological; Neurotensin; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Restriction Mapping; RNA, Messenger; Sulfur Radioisotopes; TATA Box; Transcription, Genetic | 1992 |
Subsets of neurotensin-immunoreactive neurons revealed following antagonism of the dopamine-mediated suppression of neurotensin immunoreactivity in the rat striatum.
Topics: Animals; Benzazepines; Calbindins; Caudate Nucleus; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Immunohistochemistry; Male; Neurons; Neurotensin; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; S100 Calcium Binding Protein G; Salicylamides | 1992 |
Further studies on the modulation of regional brain neurotensin concentrations by antipsychotic drugs: focus on haloperidol and BMY 14802.
Topics: Animals; Benzazepines; Brain; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Male; Neurotensin; Psychotropic Drugs; Pyrimidines; Rats; Rats, Inbred Strains; Sulpiride | 1992 |
Muscarinic antagonists attenuate neurotensin-stimulated accumbens and striatal dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Corpus Striatum; Dopamine; Electric Stimulation; Extracellular Space; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine | 1992 |
Effects of the isomers of N-n-propylnorapomorphine and haloperidol on regional concentrations of neurotensin in rat brain.
Topics: Animals; Apomorphine; Brain; Dopamine Agents; Haloperidol; Isomerism; Male; Neurotensin; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Alterations in regional brain neurotensin concentrations produced by atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzamides; Carbazoles; Caudate Nucleus; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Radioimmunoassay; Rats; Rats, Inbred Strains; Remoxipride; Sulpiride | 1991 |
Use of amfonelic acid to discriminate between classical and atypical neuroleptics and neurotensin: an in vivo voltammetric study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Cerebral Ventricles; Clozapine; Corpus Striatum; Electrochemistry; Haloperidol; Injections, Intraventricular; Male; Nalidixic Acid; Naphthyridines; Neurotensin; Perphenazine; Rats; Rats, Inbred Strains; Thioridazine | 1991 |
Effects of CI-943, a potential antipsychotic drug, and haloperidol on regional brain neurotensin concentrations.
Topics: Animals; Antipsychotic Agents; Brain; Haloperidol; Imidazoles; Male; Neurotensin; Osmolar Concentration; Pyrimidines; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
Regional characterization of brain neurotensin receptor subtypes in LS and SS mice.
Topics: Alcohol Drinking; Animals; Binding, Competitive; Brain; Chlorpheniramine; Haloperidol; Histamine H1 Antagonists; Male; Mice; Mice, Inbred Strains; Neurotensin; Piperidines; Receptors, Neurotensin; Receptors, Neurotransmitter; Sleep Stages; Species Specificity | 1991 |
Mesolimbic dopamine mediates gastric mucosal protection by central neurotensin.
Topics: Animals; Dopamine; Gastric Mucosa; Haloperidol; Hydroxydopamines; Limbic System; Male; Microinjections; Neurotensin; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Tegmentum Mesencephali | 1991 |
Inhibition of neurotensin-induced miosis by blockade of ocular dopamine pathways.
Topics: Animals; Atropine; Autonomic Nervous System; Desipramine; Dopamine; Dopamine Antagonists; Eye; Haloperidol; Hydroxydopamines; Iris; Miosis; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nerve Endings; Neurotensin; Neurotransmitter Agents; Oxidopamine; Rabbits; Receptors, Opioid, mu | 1990 |
DA2/NT receptor balance in the mesostriatal and mesolimbocortical systems after chronic treatment with typical and atypical neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Cerebral Cortex; Chlorpromazine; Clozapine; Corpus Striatum; Haloperidol; Limbic System; Male; Neurotensin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotensin; Receptors, Neurotransmitter; Thioridazine; Time Factors | 1990 |
Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons.
Topics: Animals; Cerebral Ventricles; Dopamine; Dopamine Agents; Ergolines; Haloperidol; Injections, Intraventricular; Male; Mesencephalon; Neurons; Neurotensin; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Substantia Nigra; Tegmentum Mesencephali | 1990 |
Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients.
Topics: Adult; Female; Haloperidol; Homovanillic Acid; Humans; Lithium; Male; Middle Aged; Neurotensin; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Sex Factors | 1991 |
Haloperidol rapidly increases the number of neurotensin mRNA-expressing neurons in neostriatum of the rat brain.
Topics: Animals; Autoradiography; Corpus Striatum; Gene Expression; Haloperidol; Male; Neurons; Neurotensin; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Reference Values; RNA Probes; RNA, Messenger; Sulfur Radioisotopes | 1991 |
In vivo neurochemical and behavioural effects of intracerebrally administered neurotensin and D-Trp11-neurotensin on mesolimbic and nigrostriatal dopaminergic function in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Ventricles; Corpus Striatum; Dopamine; Haloperidol; Injections; Injections, Intraventricular; Male; Motor Activity; Neurotensin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Stereotaxic Techniques; Stereotyped Behavior; Substantia Nigra | 1990 |
The effect of acute haloperidol treatment on brain proneurotensin mRNA: in situ hybridization analyses using a novel fluorescence detection procedure.
Topics: Animals; Brain; Fluorescent Dyes; Gene Expression Regulation; Haloperidol; Male; Neurotensin; Nucleic Acid Hybridization; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1990 |
Neuropeptide modulation of the behavioral effects of drugs.
Topics: Animals; Chlordiazepoxide; Columbidae; Conditioning, Psychological; Drug Interactions; Electroshock; Haloperidol; Neurotensin; Pentobarbital; Rabbits; Reinforcement, Psychology; Saimiri; Substance P; Thiazolidines; Thyrotropin-Releasing Hormone | 1985 |
Grooming behavior induced by substance P.
Topics: Animals; Dose-Response Relationship, Drug; Grooming; Haloperidol; Injections, Intraventricular; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains; Substance P | 1988 |
The effect of the stereoisomers of butaclamol on neurotensin content in discrete regions of the rat brain.
Topics: Animals; Brain; Butaclamol; Dextroamphetamine; Dibenzocycloheptenes; Haloperidol; Male; Neurotensin; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Stereoisomerism; Structure-Activity Relationship | 1988 |
Dopamine D2 receptors exert tonic regulation over discrete neurotensin systems of the rat brain.
Topics: Animals; Corpus Striatum; Haloperidol; Hydroxydopamines; Male; Neurotensin; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Reserpine; Septal Nuclei; Sulpiride | 1989 |
Neurotensin activates tuberoinfundibular dopamine neurons and increases serum corticosterone concentrations in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Animals; Arcuate Nucleus of Hypothalamus; Corpus Striatum; Corticosterone; Dihydroxyphenylalanine; Dopamine; Haloperidol; Male; Neurons; Neurotensin; Rats; Rats, Inbred Strains | 1989 |
Effects of short- and long-term haloperidol administration and withdrawal on regional brain cholecystokinin and neurotensin concentrations in the rat.
Topics: Administration, Oral; Animals; Brain Chemistry; Cholecystokinin; Haloperidol; Male; Neurotensin; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Effects of anticholinergic drugs on regional brain neurotensin concentrations.
Topics: Animals; Atropine; Brain Chemistry; Drug Interactions; Haloperidol; Male; Neurotensin; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine | 1989 |
ACTH-induced grooming behaviors and body temperature. Temporal effects of neurotensin, naloxone, and haloperidol.
Topics: Adrenocorticotropic Hormone; Animal Husbandry; Animals; Behavior, Animal; Body Temperature; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Naloxone; Neurotensin; Sodium Chloride; Time Factors | 1988 |
Comparison of bombesin-, ACTH-, and beta-endorphin-induced grooming. Antagonism by haloperidol, naloxone, and neurotensin.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Bombesin; Brain; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Naloxone; Neurotensin | 1988 |
Role of brain neurotransmitters on neurotensin-induced gastric cytoprotection.
Topics: Animals; Brain Chemistry; Cisterna Magna; Cold Temperature; Haloperidol; Humans; Injections; Injections, Intraperitoneal; Injections, Intraventricular; Male; Neurotensin; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 1985 |
Possible neuronal mechanisms involved in neurotensin-induced catalepsy in mice.
Topics: Animals; Catalepsy; Drug Interactions; Haloperidol; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Neurons; Neurotensin | 1987 |
Excessive grooming induced by somatostatin or its analog SMS 201-995.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Grooming; Haloperidol; Injections, Intraventricular; Male; Naloxone; Neurotensin; Octreotide; Rats; Rats, Inbred Strains; Receptors, Opioid; Somatostatin | 1987 |
The influence of neurotensin, naloxone, and haloperidol on elements of excessive grooming behavior induced by ACTH.
Topics: Adrenocorticotropic Hormone; Animals; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains | 1986 |
The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine.
Topics: Amygdala; Animals; Cold Temperature; Dopamine; Haloperidol; Hydroxydopamines; Male; Neurotensin; Oxidopamine; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 1987 |
Numbers of neurotensin-immunoreactive neurons selectively increased in rat ventral striatum following acute haloperidol administration.
Topics: Animals; Corpus Striatum; Haloperidol; Immunoenzyme Techniques; Male; Neurons; Neurotensin; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei.
Topics: Animals; Brain; Brain Chemistry; Clozapine; Dibenzazepines; Haloperidol; Male; Neurotensin; Rats; Rats, Inbred Strains | 1988 |
Neuroleptic drug treatment alters in vitro central neurotensin metabolism.
Topics: Animals; Cell Membrane; Chlorpromazine; Chromatography, High Pressure Liquid; Haloperidol; In Vitro Techniques; Male; Neurotensin; Rats; Rats, Inbred Strains; Synaptosomes; Time Factors | 1987 |
Neurotensin diminishes grooming and stimulates paper shredding behavior induced by water immersion of rats.
Topics: Animals; Grooming; Haloperidol; Humans; Immersion; Injections, Intraventricular; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1985 |
Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. II. Involvement of the mesolimbic dopamine system.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Corpus Striatum; Dopamine; Enkephalin, Methionine; Haloperidol; Injections, Intraventricular; Limbic System; Male; Motor Activity; Neurotensin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1985 |
Effect of neurotensin, substance P and TRH on the regulation of dopamine receptors in rat brain.
Topics: Animals; Brain; Haloperidol; In Vitro Techniques; Male; Neurotensin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Substance P; Thyrotropin-Releasing Hormone | 1984 |
Neurotensin: perchance an endogenous neuroleptic?
Topics: Analgesics; Animals; Antipsychotic Agents; Drug Synergism; Haloperidol; Humans; Hypothermia; Mice; Motor Activity; Muscle Relaxation; Neurotensin; Rats; Stereotyped Behavior | 1980 |
Increase of neurotensin content elicited by neuroleptics in nucleus accumbens.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Radioimmunoassay; Rats; Septal Nuclei | 1980 |
Cytoprotective effect of centrally administered neurotensin on stress-induced gastric ulcers.
Topics: Animals; Cimetidine; Cold Temperature; Food Deprivation; Gastric Mucosa; Haloperidol; Male; Neurotensin; Oxotremorine; Rats; Rats, Inbred Strains; Restraint, Physical; Somatostatin; Stomach Ulcer; Stress, Physiological | 1982 |
Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Microinjections; Motor Activity; Neurotensin; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1983 |
Neurotensin-induced hypothermia: evidence for an interaction with dopaminergic systems and the hypothalamic--pituitary--thyroid axis.
Topics: Animals; Body Temperature Regulation; Fenclonine; Haloperidol; Hydroxydopamines; Hypothalamo-Hypophyseal System; Male; Neurotensin; Rats; Receptors, Dopamine; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine | 1980 |
Neurotensin blocks certain amphetamine-induced behaviours.
Topics: Animals; Behavior, Animal; Caudate Nucleus; Dextroamphetamine; Dopamine; Haloperidol; Male; Motor Activity; Movement; Neurotensin; Nucleus Accumbens; Rats; Septal Nuclei | 1981 |
Electrophysiological actions of neurotensin in rat cerebellum.
Topics: Action Potentials; Animals; Haloperidol; Hydroxydopamines; Iontophoresis; Magnesium; Magnesium Chloride; Male; Neurons; Neurotensin; Pressure; Purkinje Cells; Rats; Stereoisomerism | 1980 |
CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates.
Topics: Adult; Female; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Neurotensin; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1994 |
Up-regulation of neurotensin mRNA in the rat striatum after acute methamphetamine treatment.
Topics: Animals; Autoradiography; Caffeine; Corpus Striatum; Gene Expression Regulation; Haloperidol; Male; Methamphetamine; Neurotensin; Olfactory Bulb; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Substance P; Sulfur Radioisotopes; Time Factors | 1994 |
Neurochemical heterogeneity of the primate nucleus accumbens.
Topics: Animals; Basal Ganglia; Brain Mapping; Dopamine; Female; Haloperidol; Immunohistochemistry; Macaca; Male; Neuropeptides; Neurotensin; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Substance P | 1995 |
Ontogeny of the effect of antipsychotic drug treatment on neurotensin concentrations in the rat brain.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Brain; Brain Chemistry; Female; Haloperidol; Male; Neurotensin; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1995 |
Novel dopamine receptor subtypes as targets for antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Bradykinin; Brain; Carbachol; Cell Division; Cyclic AMP; Dopamine; Dopamine Agonists; Ergolines; Gene Expression; Genes, fos; Haloperidol; Humans; Inositol Phosphates; Neurotensin; Oxidopamine; Quinpirole; Receptors, Dopamine; Second Messenger Systems; Signal Transduction; Virulence Factors, Bordetella | 1995 |
C-fos mediates antipsychotic-induced neurotensin gene expression in the rodent striatum.
Topics: Animals; Base Sequence; Biotin; Blotting, Northern; Gene Expression; Genes, fos; Haloperidol; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Molecular Sequence Data; Neostriatum; Neurotensin; Oligonucleotides, Antisense; Rats; Rats, Wistar; RNA, Messenger | 1995 |
Effects of the sigma receptor ligand SR 31742A on neurotensin biosynthesis in rat basal ganglia.
Topics: Animals; Autoradiography; Azepines; Basal Ganglia; Haloperidol; In Situ Hybridization; Ligands; Limbic System; Neuropeptides; Neurotensin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, sigma; RNA Probes; RNA, Messenger | 1995 |
c-fos antisense oligonucleotide specifically attenuates haloperidol-induced increases in neurotensin/neuromedin N mRNA expression in rat dorsal striatum.
Topics: Animals; Antipsychotic Agents; Base Sequence; Corpus Striatum; DNA, Antisense; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Molecular Sequence Data; Neurotensin; Peptide Fragments; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcriptional Activation | 1994 |
Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine Agents; Haloperidol; In Vitro Techniques; Male; Metalloendopeptidases; Neurotensin; Rats; Rats, Sprague-Dawley | 1994 |
Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Extrapyramidal Tracts; Globus Pallidus; Hallucinogens; Haloperidol; Limbic System; Male; Methamphetamine; Neurotensin; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1994 |
Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol.
Topics: Animals; Antipsychotic Agents; Gene Expression Regulation; Haloperidol; Male; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions.
Topics: Animals; Clozapine; Corpus Striatum; Genes, fos; Haloperidol; Male; Neurotensin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger | 1994 |
Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens.
Topics: Animals; Benzazepines; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sulpiride; Transcription, Genetic | 1994 |
Effects of haloperidol, quinelorane, and lithium on regional neurotensin/neuromedin N concentrations: further evidence for neurotensin/neuromedin N-dopamine interactions.
Topics: Animals; Brain; Dopamine; Dopamine Agonists; Haloperidol; Lithium; Male; Neurotensin; Osmolar Concentration; Peptide Fragments; Quinolines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1994 |
The sigma receptor ligand SR 31742A increases neurotensin in the nucleus accumbens but not in the caudate-putamen of the rat.
Topics: Animals; Antipsychotic Agents; Azepines; Caudate Nucleus; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraperitoneal; Neurotensin; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley | 1993 |
Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Benzazepines; Corpus Striatum; Ergolines; Gene Expression; Genes; Genes, fos; Haloperidol; In Situ Hybridization; Male; Neurons; Neurotensin; Nucleus Accumbens; Peptide Fragments; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger | 1993 |
Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: comparison with acute haloperidol effects.
Topics: Animals; Gene Expression Regulation; Haloperidol; Male; Methamphetamine; Neostriatum; Neurotensin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression.
Topics: Aging; Analysis of Variance; Animals; Autoradiography; Corpus Striatum; Gene Expression; Haloperidol; In Situ Hybridization; Male; Neurotensin; Rats; Rats, Inbred F344; Receptors, Dopamine D2; RNA, Messenger; Sulfur Radioisotopes | 1993 |
Evidence for in vivo interactions between neuropeptide Y-related peptides and sigma receptors in the mouse hippocampal formation.
Topics: Animals; Binding, Competitive; Epinephrine; Gastrointestinal Hormones; Haloperidol; Hippocampus; Kinetics; Male; Mice; Mice, Inbred Strains; Neuropeptide Y; Neurotensin; Peptide YY; Peptides; Phenazocine; Receptors, sigma; Vasoactive Intestinal Peptide | 1993 |
Effect of muscimol on haloperidol-induced alteration of neurotensin gene expression in the striatum and nucleus accumbens in the rat.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; GABA Agonists; Gene Expression Regulation; Haloperidol; Male; Muscimol; Neurotensin; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats.
Topics: Animals; Caudate Nucleus; Dopamine; Dopamine Antagonists; Female; Haloperidol; Microdialysis; Neurotensin; Potassium; Prefrontal Cortex; Putamen; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Morphologically distinct subpopulations of neurotensin-immunoreactive striatal neurons observed in rat following dopamine depletions and D2 receptor blockade project to the globus pallidus.
Topics: Animals; Axonal Transport; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Fluorescent Antibody Technique; Fluorescent Dyes; Globus Pallidus; Haloperidol; Male; Mesencephalon; Neurotensin; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine; Stilbamidines | 1996 |
Temporal dissociation of neurotensin/neuromedin N mRNA expression in topographically separate subsets of rat striatal neurons following administration of haloperidol.
Topics: Animals; Antipsychotic Agents; Brain Mapping; Corpus Striatum; Haloperidol; Histocytochemistry; In Situ Hybridization; Male; Neurons; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Comparison of neurotensin responses to MDL 100,907, a selective 5HT2A antagonist, with clozapine and haloperidol.
Topics: Animals; Caudate Nucleus; Clozapine; Fluorobenzenes; Globus Pallidus; Haloperidol; Male; Neurotensin; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 1997 |
Phenotypic characterization of neurotensin messenger RNA-expressing cells in the neuroleptic-treated rat striatum: a detailed cellular co-expression study.
Topics: Animals; Antipsychotic Agents; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Haloperidol; In Situ Hybridization; Male; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Nucleus Accumbens; Oligonucleotides; Phenotype; Phosphoproteins; Rats; Rats, Wistar; RNA, Messenger; Substance P | 1997 |
EEDQ reduces the striatal neurotensin mRNA response to haloperidol.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Dopamine Antagonists; Gene Expression Regulation; Haloperidol; Male; Neurotensin; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, sigma; RNA, Messenger | 1997 |
Haloperidol regulates neurotensin gene expression in striatum of c-fos-deficient mice.
Topics: Animals; Corpus Striatum; Gene Expression; Haloperidol; In Situ Hybridization; Mice; Mice, Knockout; Neurotensin; Proto-Oncogene Proteins c-fos | 1997 |
Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems.
Topics: Animals; Anti-Dyskinesia Agents; Extrapyramidal Tracts; Haloperidol; Immune System; Limbic System; Male; Neurotensin; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Ventral Tegmental Area; Visual Cortex | 1997 |
Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Corpus Striatum; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Haloperidol; Mice; Mice, Mutant Strains; Neurotensin; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D2; RNA, Messenger; Signal Transduction; Sulpiride; Transcription, Genetic; Transcriptional Activation | 1997 |
Pharmacological evidence that neurotensin mediates prolactin-induced activation of tuberoinfundibular dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arcuate Nucleus of Hypothalamus; Binding, Competitive; Dopamine; Dopamine Antagonists; Female; Haloperidol; Male; Median Eminence; Neurons; Neurotensin; Prolactin; Pyrazoles; Quinolines; Rats; Rats, Inbred Strains; Receptors, Neurotensin; Sex Factors | 1998 |
Desensitization and enhancement of neurotensin/neuromedin N mRNA responses in subsets of rat caudate-putamen neurons following multiple administrations of haloperidol.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Dopamine; Dopamine Antagonists; Gene Expression; Haloperidol; Neostriatum; Neurons; Neurotensin; Peptide Fragments; Rats; RNA, Messenger | 1998 |
Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Corpus Striatum; Haloperidol; Infusion Pumps; Male; Microdialysis; Neurotensin; Nucleus Accumbens; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Distinct and interactive effects of d-amphetamine and haloperidol on levels of neurotensin and its mRNA in subterritories in the dorsal and ventral striatum of the rat.
Topics: Animals; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Drug Interactions; Haloperidol; Immunohistochemistry; Male; Neurotensin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution | 1998 |
Clozapine and haloperidol block the induction of behavioral sensitization to amphetamine and associated genomic responses in rats.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Gene Expression Regulation; Genes, fos; Haloperidol; In Situ Hybridization; Injections, Subcutaneous; Male; Motor Activity; Neurotensin; Nucleus Accumbens; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Increased levels of proneurotensin/neuromedin N mRNA in rat striatum and nucleus accumbens induced by 7-OH-DPAT and nafadotride.
Topics: Animals; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Gene Expression Regulation; Haloperidol; Male; Naphthalenes; Neurotensin; Nucleus Accumbens; Peptide Fragments; Protein Precursors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Transcription, Genetic | 1999 |
Role of adenosine and N-methyl-D-aspartate receptors in mediating haloperidol-induced gene expression and catalepsy.
Topics: Animals; Autoradiography; Catalepsy; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Genes, fos; Haloperidol; In Situ Hybridization; Male; Neuroprotective Agents; Neurotensin; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Purinergic P1 | 1999 |
Effects of a novel neurotensin peptide analog given extracranially on CNS behaviors mediated by apomorphine and haloperidol.
Topics: Animals; Apomorphine; Behavior, Animal; Body Temperature; Catalepsy; Clozapine; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Contrasting patterns and cellular specificity of transcriptional regulation of the nuclear receptor nerve growth factor-inducible B by haloperidol and clozapine in the rat forebrain.
Topics: Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; DNA-Binding Proteins; Drug Administration Schedule; Dynorphins; Enkephalins; Gene Expression Regulation; Haloperidol; In Situ Hybridization; Male; Neurons; Neurotensin; Nuclear Receptor Subfamily 4, Group A, Member 1; Nucleus Accumbens; Organ Specificity; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2000 |
The effects of acute antipsychotic drug administration on the neurotensin system of the developing rat brain.
Topics: Aging; Animals; Animals, Newborn; Antipsychotic Agents; Brain; Caudate Nucleus; Female; Haloperidol; Male; Neurotensin; Nucleus Accumbens; Osmolar Concentration; Peptide Fragments; Putamen; Rats; RNA, Messenger | 2000 |
Neurotensin gene expression and behavioral responses following administration of psychostimulants and antipsychotic drugs in dopamine D(3) receptor deficient mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Brain; Catalepsy; Cocaine; Dopamine Uptake Inhibitors; Female; Gene Expression; Haloperidol; Male; Mice; Mice, Mutant Strains; Motor Activity; Neurotensin; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger | 2001 |
Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.
Topics: Acoustic Stimulation; Adamantane; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Conditioning, Classical; Dibenzothiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Haloperidol; Imidazoles; Inhibition, Psychological; Neurotensin; Photic Stimulation; Psychomotor Performance; Quetiapine Fumarate; Rats; Rats, Long-Evans; Reaction Time; Receptors, Neurotensin; Reflex, Startle; RNA, Messenger; Schizophrenia; Social Isolation; Synaptic Transmission | 2001 |
Endogenous neurotensin down-regulates dopamine efflux in the nucleus accumbens as revealed by SR-142948A, a selective neurotensin receptor antagonist.
Topics: Adamantane; Animals; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Haloperidol; Imidazoles; Male; Neurotensin; Nucleus Accumbens; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Stimulation, Chemical | 2001 |
Neurotensin-deficient mice show altered responses to antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Catalepsy; Gene Deletion; Gene Targeting; Haloperidol; Mice; Molecular Sequence Data; Neurotensin | 2001 |
Neurotensin levels in specific brain regions and hypnotic sensitivity to ethanol and pentobarbital as a function of time after haloperidol administration in selectively bred rat lines.
Topics: Alcoholic Intoxication; Animals; Antipsychotic Agents; Brain Chemistry; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Haloperidol; Hypnotics and Sedatives; Neurotensin; Pentobarbital; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 2001 |
Neurotensin analog selective for hypothermia over antinociception and exhibiting atypical neuroleptic-like properties.
Topics: Analgesics; Animals; Antipsychotic Agents; Blood-Brain Barrier; Body Temperature; Catalepsy; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothermia; Injections, Intraperitoneal; Male; Neurotensin; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin | 2001 |
Effects of haloperidol and risperidone on neurotensin levels in brain regions and neurotensin efflux in the ventral striatum of the rat.
Topics: Animals; Antipsychotic Agents; Basal Ganglia; Brain; Central Nervous System Stimulants; Dextroamphetamine; Dialysis Solutions; Haloperidol; Male; Microdialysis; Neurotensin; Rats; Rats, Wistar; Risperidone; Tissue Distribution | 2002 |
Repeated administration of the neurotensin analogue NT69L induces tolerance to its suppressant effect on conditioned avoidance behaviour.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Haloperidol; Male; Neurotensin; Peptide Fragments; Rats; Rats, Wistar; Time Factors | 2002 |
Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, potentiates neurochemical and behavioral effects of haloperidol in the rat.
Topics: Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Catalepsy; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Enkephalins; gamma-Aminobutyric Acid; Haloperidol; Histamine Antagonists; Imidazoles; In Situ Hybridization; Ligands; Male; Motor Activity; Neurons; Neurotensin; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Histamine H3; RNA, Messenger; Up-Regulation | 2002 |
Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Brain; Clozapine; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; In Situ Hybridization; Isoenzymes; Male; Models, Animal; Neurotensin; Protein Precursors; Rats; Receptors, Dopamine; RNA, Messenger; Schizophrenia; Time Factors | 2003 |
Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood-brain barrier.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Blood-Brain Barrier; Body Temperature; Brain; Catalepsy; Cocaine; Drug Tolerance; Haloperidol; Hyperkinesis; Hypothermia; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Altered neurotensin mrna expression in mice lacking the dopamine transporter.
Topics: Amphetamine; Animals; Brain; Dopamine Agents; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Gene Expression; Haloperidol; In Situ Hybridization; Membrane Glycoproteins; Membrane Transport Proteins; Mental Disorders; Mice; Nerve Tissue Proteins; Neurotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Reversal of sensorimotor gating deficits in Brattleboro rats by acute administration of clozapine and a neurotensin agonist, but not haloperidol: a potential predictive model for novel antipsychotic effects.
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Gait Disorders, Neurologic; Haloperidol; Inhibition, Psychological; Male; Neurotensin; Rats; Rats, Brattleboro; Rats, Long-Evans; Reflex, Startle; Schizophrenia; Species Specificity | 2004 |
Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy.
Topics: Age Factors; Animals; Behavior, Animal; Benzazepines; Carbidopa; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression; Haloperidol; In Situ Hybridization; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurotensin; Pyrazoles; Quinolines; Receptors, Neurotensin; RNA, Messenger; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
The inhibitory effect of neurotensin on synaptosomal membrane Na+, K+-ATPase is altered by antipsychotic administration.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Cerebral Cortex; Clozapine; Haloperidol; Male; Neurotensin; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Synaptosomes | 2005 |
Neurotensin-deficient mice have deficits in prepulse inhibition: restoration by clozapine but not haloperidol, olanzapine, or quetiapine.
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Body Weight; Clozapine; Dibenzothiazepines; Female; Haloperidol; Male; Mice; Mice, Inbred C57BL; Neurotensin; Olanzapine; Quetiapine Fumarate; Reflex; Reflex, Startle | 2005 |
Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues.
Topics: Animals; Antipsychotic Agents; Area Under Curve; Arginine; Biological Availability; Catalepsy; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Design; Haloperidol; Injections, Intraperitoneal; Lysine; Male; Motor Activity; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin | 2005 |
Effects of acute and subchronic d-amphetamine on ventral striatal concentrations of neurotensin and neuropeptide Y in rats treated with antipsychotic drugs.
Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Corpus Striatum; Drug Administration Schedule; Drug Interactions; Extracellular Fluid; Haloperidol; Male; Microdialysis; Neuropeptide Y; Neurotensin; Radioimmunoassay; Rats; Rats, Wistar; Risperidone; Time Factors | 2006 |
Typical and atypical antipsychotic drugs target dopamine and cyclic AMP-regulated phosphoprotein, 32 kDa and neurotensin-containing neurons, but not GABAergic interneurons in the shell of nucleus accumbens of ventral striatum.
Topics: Animals; Antipsychotic Agents; Calbindin 1; Calbindin 2; Calbindins; Cell Count; Clozapine; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Fluorescent Antibody Technique; Gene Expression; Haloperidol; Male; Neurons; Neurotensin; Nucleus Accumbens; Parvalbumins; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G | 2006 |
Neurotensin afferents of the ventral tegmental area in the rat: [1] re-examination of their origins and [2] responses to acute psychostimulant and antipsychotic drug administration.
Topics: Afferent Pathways; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Colchicine; Haloperidol; Immunohistochemistry; In Situ Hybridization; Male; Methamphetamine; Neurotensin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ventral Tegmental Area | 2006 |
Electrophysiological and behavioral effects of neurotensin in rat globus pallidus: an in vivo study.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Dystonia; Electrophysiology; Globus Pallidus; Haloperidol; Injections, Intraperitoneal; Male; Microinjections; Motor Activity; Neurons; Neurotensin; Osmolar Concentration; Peptide Fragments; Rats; Rats, Wistar; Receptors, Neurotensin | 2007 |
The effects of chronic administration of established and putative antipsychotics on natural prepulse inhibition deficits in Brattleboro rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Arginine Vasopressin; Clozapine; Deamino Arginine Vasopressin; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Habituation, Psychophysiologic; Haloperidol; Neural Inhibition; Neurotensin; Rats; Rats, Brattleboro; Rats, Long-Evans; Rats, Mutant Strains; Reflex, Startle; Risperidone; Schizophrenia; Statistics, Nonparametric | 2007 |
The neurotensin analog NT69L enhances medial prefrontal cortical dopamine and acetylcholine efflux: potentiation of risperidone-, but not haloperidol-, induced dopamine efflux.
Topics: Acetylcholine; Analysis of Variance; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Male; Microdialysis; Neurotensin; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone | 2007 |
Endogenous neurotensin is involved in estrous cycle related alterations in prepulse inhibition of the acoustic startle reflex in female rats.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antipsychotic Agents; Circadian Rhythm; Diestrus; Estrous Cycle; Female; Haloperidol; Inhibition, Psychological; Neural Inhibition; Neurotensin; Proestrus; Pyrazoles; Quinolines; Rats; Rats, Long-Evans; Reaction Time; Receptors, Neurotensin; Reflex, Startle; Sex Factors; Time Factors | 2008 |
Chronic NT69L potently prevents drug-induced disruption of prepulse inhibition without causing tolerance.
Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Haloperidol; Neurotensin; Peptide Fragments; Rats; Sensory Gating | 2010 |
Effects of pallidal neurotensin on haloperidol-induced parkinsonian catalepsy: behavioral and electrophysiological studies.
Topics: Animals; Antipsychotic Agents; Catalepsy; Disease Models, Animal; Dyskinesia, Drug-Induced; Globus Pallidus; Haloperidol; Male; Neurotensin; Parkinsonian Disorders; Rats; Rats, Wistar | 2010 |
The neurotensin-1 receptor agonist PD149163 inhibits conditioned avoidance responding without producing catalepsy in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Central Nervous System Stimulants; Clozapine; Conditioning, Classical; Dextroamphetamine; Drug Evaluation, Preclinical; Haloperidol; Male; Neurotensin; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin | 2011 |
Acute, but not repeated, administration of the neurotensin NTS1 receptor agonist PD149163 decreases conditioned footshock-induced ultrasonic vocalizations in rats.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Buspirone; Catalepsy; Conditioning, Psychological; Drug Tolerance; Electroshock; Fear; Haloperidol; Male; Neurotensin; Rats; Rats, Wistar; Receptors, Neurotensin; Vocalization, Animal | 2014 |
Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment.
Topics: Amphetamine; Animals; Antipsychotic Agents; Caudate Nucleus; Central Nervous System Stimulants; Dopamine; Haloperidol; Male; Movement; Neurotensin; Nucleus Accumbens; Putamen; Rats, Sprague-Dawley; Receptors, Neurotensin; RNA, Messenger | 2017 |