haloperidol has been researched along with naloxone in 244 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 146 (59.84) | 18.7374 |
| 1990's | 53 (21.72) | 18.2507 |
| 2000's | 22 (9.02) | 29.6817 |
| 2010's | 22 (9.02) | 24.3611 |
| 2020's | 1 (0.41) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA | 1 |
| Foulon, C; Kung, HF; Kung, MP | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Ehret, A; Jackisch, R; Maier, CA; Predoiu, U; Soukara, S; Wünsch, B | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Weigl, M; Wünsch, B | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Englberger, W; Geiger, C; Lehmkuhl, K; Schepmann, D; Wünsch, B; Zelenka, C | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bourgeois, C; Christoph, T; Englberger, W; Galla, F; Galla, HJ; Hüwel, S; Kögel, B; Lehmkuhl, K; Schepmann, D; Soeberdt, M; Straßburger, W; Torres-Gómez, H; Werfel, E; Wünsch, B | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abels, C; Aerts, SN; Autar, R; Bolster, MG; Bouzanne des Mazery, R; Frehland, B; Huang, TY; Knie, U; Lai, CC; Lin, KY; Lotts, T; Metze, D; Molenveld, P; Schepmann, D; Soeberdt, M; Ständer, S; Sterk, GJ; Storcken, RP; Tangherlini, G; van Holst, FR; Wagner, C; Wegert, A; Wünsch, B | 1 |
| Che, T; Kalinin, DV; Loser, K; Mykicki, N; Schepmann, D; Ständer, S; Tangherlini, G; Wünsch, B | 1 |
| Aiello, D; Diana, P; Jonas, H; Schepmann, D; Wünsch, B | 1 |
| Bennett, JP; Burt, DR; Bylund, DB; Charness, ME; Creese, I; Enna, SJ; Simantov, R; Snyder, SH; Yamamura, HI | 1 |
| Gershon, S; Hine, B | 1 |
| Billingsley, ML; Goldstein, JM; Kubena, RK; Malick, JB | 1 |
| Hartley, EJ; McManus, C; Seeman, P | 1 |
| Segal, DS | 1 |
| Chesher, GB; Jackson, DM; Malor, R; Zaluzny, SG | 1 |
| Bruinvels, J; Moleman, P; Versluis, DJ | 1 |
| Extein, I; Gold, MS; Kleber, HD; Pottash, AL; Redmond, DE | 1 |
| Dzoljic, MR; van der Lely, AJ; von Mourik, JB | 1 |
| Quock, RM | 1 |
| Eidelberg, E; Erspamer, R | 1 |
| Durham, HD; Frank, GB; Marwaha, J | 1 |
| Chan, SH; Lee, CM; Wong, PC | 1 |
| Jacob, JJ; Ramabadran, K | 1 |
| Donabedian, RK; Gold, MS; Redmond, DE | 1 |
| Head, M; Lal, H; Mantione, C; Puri, S; Valentino, D | 1 |
| Dunn, AJ; Green, EJ; Isaacson, RL; Lanthorn, TH | 1 |
| Carrasco, MA; Dias, RD; Izquierdo, I; Souza, DO | 1 |
| Berge, OG; Bergslien, H; Hole, K; Jørgensen, HA; Reichelt, KL; Trygstad, OE | 1 |
| Extein, I; Goodwin, FK; Lo, C; Schoenfeld, RI | 1 |
| Rivier, C; Vale, W | 1 |
| Heinz, G; Jurna, I | 2 |
| Persson, SA | 1 |
| Iversen, SD; Joyce, EM | 1 |
| Lefebvre, RA; Willems, JL | 1 |
| Pert, A; Sivit, C | 1 |
| Kim, C; Van Loon, GR | 1 |
| Cowan, A; Dettmar, PW; Walter, DS | 2 |
| Muraki, T; Tokunaga, Y | 1 |
| Takemori, AE; Tulunay, FC; Yano, I | 1 |
| Carlson, KR; Eibergen, RD | 1 |
| Bloom, F; Browne, RG; Guillemin, R; Ling, N; Segal, DS | 1 |
| Colpaert, FC; Janssen, PA; Niemegeers, CJ | 1 |
| Freye, E; Kuschinsky, K | 1 |
| Brase, DA; Loh, HH; Tseng, LF | 1 |
| Brougham, LR; Clay, GA | 1 |
| Sparber, SB; Takemori, AE; Tulunay, FC | 1 |
| Pert, CB; Snyder, SH | 1 |
| Friedman, E; Gershon, S; Hine, B; Torrelio, M | 1 |
| Henderson, GL; Westkaemper, R | 1 |
| Bidzseranova, A; Telegdy, G; Várga, J | 1 |
| Borowski, TB; Kokkinidis, L | 1 |
| Austin, MC; Churchill, L; Kalivas, PW | 1 |
| Montastruc, JL; Montastruc, P; Rascol, O | 1 |
| Yanagita, T | 1 |
| Sagrillo, CA; Voogt, JL | 1 |
| Kulkarni, SK; Verma, A | 1 |
| Kornetsky, C; Pollock, J | 1 |
| Gokin, AP; Karpukhina, MV; Tikhomirov, NE | 1 |
| Krowicki, ZK | 1 |
| Bidzseranova, A; Penke, B; Telegdy, G; Tóth, G | 1 |
| Guo, SY; Sato, T; Takeshige, C; Tsuchiya, M | 1 |
| Choudhary, AK; Gurtu, S; Mukherjee, D; Seth, S; Sinha, JN | 1 |
| Hernandez, DE; Jennes, L | 1 |
| Datta, H; Saha, N; Sharma, PL | 1 |
| Kuribara, H; Tadokoro, S | 1 |
| Gubina, GI; Kadagidze, ZG; Kharkevich, DD | 1 |
| Defaux, JP; Junien, JL; Pascaud, X; Rozé, C | 1 |
| de la Cruz, F; Junquera, J; Russek, M | 1 |
| Funahashi, M; Hayashida, H; Hori, O; Kimura, H; Kohda, H | 1 |
| Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van de Buuse, M; van Wimersma Greidanus, TB | 1 |
| Maigret, C; Van Wimersma Greidanus, TB | 1 |
| Becú-Villalobos, D; Lacau-Mengido, IM; Libertun, C | 1 |
| Bullock, A; Dannals, RF; Frost, JF; Kuhar, MJ; Leonhardt, S; Lyon, RA; Price, DL; Rydelek, LT; Struble, RG; Titeler, M | 1 |
| Lang, IM; Marvig, J | 1 |
| Agarwal, RK; Dixit, KS; Pandey, US; Shukla, N; Singh, SK | 1 |
| Colbern, DL; Twombly, DA | 1 |
| Arissen, SM; de Bruijckere, LM; de Koning, EJ; Donker, DK; Hulshof, RL; Pabst, PH; Ruesink, RW; van Berckel, BN; van de Brug, F; van Wimersma Greidanus, TB | 1 |
| Glick, SD; Hough, LB; Su, K | 1 |
| Aihara, H; Araki, H | 1 |
| Gebhart, GF; Ossipov, MH | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Collu, M; Fratta, W; Gessa, GL; Martellotta, MC; Muntoni, F; Pichiri, M | 1 |
| Krechting, B; Maigret, C; Van Wimersma Greidanus, TB | 1 |
| Leung, MK; Martinez, EA; Murray, M; Stefano, GB | 1 |
| Chahl, LA; Corlis, A; Kavanagh, CA | 1 |
| Matsubara, K; Matsushita, A | 1 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Shearman, GT; Zeugner, H | 1 |
| Colbern, DL; Maigret, C; Spruijt, BM; Ten Haaf, JA; van Wimersma Greidanus, TB | 1 |
| Bagley, RB; Compton, DR; Katzen, JS; Martin, BR | 1 |
| Bouquet, Y; De Rycke, PH; Kennes, D; Odberg, FO | 1 |
| Bragin, EO | 1 |
| Buydens, P; Finné, E; Golstein, J; Vanhaelst, L; Velkeniers, B | 1 |
| Martínez, JA; Milanés, MV; Vargas, ML | 1 |
| Seifert, WF; van Ree, JM; van Wolfswinkel, L | 1 |
| Perry, DC | 1 |
| Allikmets, LKh; Soosaar, AKh; Vasar, EE | 1 |
| Carvey, P; Goetz, CG; Klawans, HL; Paulseth, JE | 1 |
| Duffy, P; Kalivas, PW; Latimer, LG | 1 |
| Amir, S | 1 |
| Király, I; Van Ree, JM | 1 |
| Baran, J; Kolasiewicz, W; Wolfarth, S | 1 |
| Caldwell, JD; Drago, F; Pedersen, CA; Prange, AJ | 1 |
| Havemann, U; Kuschinsky, K; Themann, P | 1 |
| Ben Natan, L; Costentin, J; Gonzales-Rios, F; Protais, P; Vlaiculescu, A | 1 |
| Flechter, S; Graff, E; Oberman, Z; Rabey, JM; Vardi, J | 1 |
| Bantutova, I; Iakimova, K; Koleva, E; Ovcharova, R | 1 |
| Berendsen, HH; Gower, AJ | 1 |
| Clark, RD; Katz, JL; Spealman, RD | 1 |
| Artalejo, AR; García, AG; Montiel, C; Sánchez-García, P | 1 |
| Colbern, DL; Van Wimersma Greidanus, TJ; Van Zinnicq Bergmann, FF | 1 |
| Holtzman, SG | 1 |
| Drago, F; Kovács, GL; Scapagnini, U; Szabo, G; Telegdy, G | 1 |
| Bell, RD; Cicero, TJ; Meyer, ER | 1 |
| Eades, CG; Flanary, HG; Martin, WR; Thompson, JA; Thompson, WO | 1 |
| Lal, H; Niemegeers, CJ; Wauquier, A | 1 |
| Moon, SL | 1 |
| Boublik, JH; Funder, JW | 1 |
| Herz, A; Osborne, H | 1 |
| Eldridge, FL; Millhorn, DE; Waldrop, TG | 1 |
| Ristine, LA; Spear, LP | 1 |
| Dubinsky, B; Janssen, PA; McGuire, JL; McKenzie, BE; Niemegeers, CJ; Weintraub, HS | 1 |
| Milanés, MV; Puig, MM; Vargas, ML | 2 |
| Foong, FW; Satoh, M | 1 |
| Billington, CJ; Gerritsen, GC; Levine, AS; Morley, JE | 1 |
| Overstreet, D; Pilotto, R; Singer, G | 1 |
| Leysen, JE; Van Gompel, P | 1 |
| Borsy, J; Gráf, L; Király, I; Tapfer, M | 1 |
| Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van Ree, JM; van Wimersma Greidanus, TB | 1 |
| Carlson, KR; Seeger, TF | 1 |
| Berzétei, IP; Csaba, G; Dobozy, O; Kurgyis, J; Rónai, AZ | 1 |
| Graudenz, M; Izquierdo, I | 1 |
| Kovács, GL; Penke, B; Szabó, G; Telegdy, G | 1 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Murray, SS | 1 |
| Chan, HK; Chen, CF; Lin, MT; Teh, GW | 1 |
| Cowan, A; Gmerek, DE | 1 |
| Brakkee, JH; Gispen, WH; Hannigan, JH; Isaacson, RL | 1 |
| Chen, CF; Chuang, KS; Lin, MT | 1 |
| Johnson, KM; Leventer, SM | 1 |
| Balsara, JJ; Burte, NP; Chandorkar, AG; Jadhav, JH; Nandal, NV | 1 |
| Cianchetti, C; Giordano, G; Masala, C; Olivari, P | 1 |
| Assan, R; Gilbert, M; Helman, A; Pfister-Lemaire, N; Réach, G | 1 |
| Masters, DB; Tomie, A; Wagner, GC | 1 |
| Forman, LJ; Meites, J; Miki, N; Ramos, T; Sonntag, WE | 1 |
| Caccamo, G; Continella, G; Drago, F; Scapagnini, U | 1 |
| Sakakibara, S | 1 |
| Kameyama, T; Nagasaka, M | 1 |
| Dunbar, E; Swartz, CM | 1 |
| Forsling, ML; Williams, H | 1 |
| Franko, CM; Tomie, A; Wagner, GC | 1 |
| Boni, B; Casacchia, M; Cerbo, R; Cesarino, F; De Lena, C; Feliciani, M; Formisano, R; Meco, G | 1 |
| Shuster, L; Thompson, ML; Weiss, J | 1 |
| Cairnie, AB; Leach, KE | 1 |
| Dzoljic, MR; van der Poel-Heisterkamp, AL | 1 |
| Kummer, P; Stock, G | 1 |
| Barreca, T; Magnani, G; Marabini, A; Rolandi, E; Sannia, A | 1 |
| Baggio, G; Ferrari, F | 1 |
| Boschi, G; Launay, N; Rips, R | 1 |
| Berkowitz, BA; Hynes, MD | 1 |
| Gudelsky, GA | 1 |
| Levine, AS; Morley, JE | 1 |
| Carson, PE; Feigenbaum, JJ; Klawans, HL; Moon, BH | 1 |
| Cervo, L; Mennini, T; Poggesi, E; Rochat, C; Samanin, R | 1 |
| Broekkamp, CL; Dunstan, R; Lloyd, KG | 1 |
| Mintz, M; Myslobodsky, MS | 1 |
| Zetler, G | 1 |
| Schechter, MD | 1 |
| Kneip, J; Levine, AS; Morley, JE | 1 |
| Hynes, M; Lal, H; Shearman, GT | 1 |
| Booth, NH; Keith, JC; Kemppainen, RJ; Wilson, RC | 1 |
| Barden, N; Cusan, L; Dupont, A; Labrie, F; Mérand, Y; Vaudry, H | 1 |
| McMillen, BA | 1 |
| Gardner, EL; Nazzaro, JM; Seeger, TF | 1 |
| Deyashiki, Y; Hara, A; Matsuura, K; Miyabe, Y; Ohara, H | 1 |
| Chien, CC; Pasternak, GW | 1 |
| Misawa, M; Mori, T; Suzuki, T; Tsuji, M | 1 |
| Fukase, H; Fukuzaki, K; Koja, T; Lukas, SE; Nagata, R | 1 |
| Kreeger, JS; Larson, AA | 1 |
| Eyl, C; Hakan, RL; Hart, C | 1 |
| Morimoto, Y; Morio, Y; Tanimoto, H; Yakushiji, T | 1 |
| Shi, GG; Wei, DS; Xu, SF | 1 |
| Di Giannuario, A; Loizzo, A; Luzi, M; Pieretti, S | 1 |
| Josephy, M; Mudde, M; Spruijt, BM; Willemse, T | 1 |
| Borg, PJ; Taylor, DA | 1 |
| Havemann-Reinecke, U; Magnus-Ellenbroek, B | 1 |
| Egan, MF; Ferguson, JN; Hyde, TM | 1 |
| Chien, CC; Pasternak, GW; Ryan-Moro, J; Standifer, KM | 1 |
| Costentin, J; Florin, S; Meunier, JC; Suaudeau, C | 1 |
| Su, TP; Tsao, LI | 1 |
| Gupta, MC; Singh, J | 1 |
| Burden, HW; Davis, MC; Hodson, CA | 1 |
| Franco, AC; Prado, WA | 1 |
| Biró, E; Penke, B; Telegdy, G | 1 |
| Bittencourt, AL; Takahashi, RN | 1 |
| Forsling, ML; Yasin, SA | 1 |
| Chamorro, A; Vila, N | 1 |
| Arnsten, AF; Goldman-Rakic, PS | 1 |
| Ballard, TM; McAllister, KH | 1 |
| Kovács, A; Penke, B; Telegdy, G; Tóth, G | 1 |
| Besson, MJ; Mavridis, M | 1 |
| Miñarro, J; Pinazo, J; Rodríguez-Arias, M; Stinus, L | 1 |
| Besson, A; Eschalier, A; Fialip, J; Privat, AM | 1 |
| Gevaerd, MS; Sultowski, ET; Takahashi, RN | 1 |
| Ho, IK; Jang, C; Loh, HH; Ma, T; Park, Y; Tanaka, S | 1 |
| Adamik, A; Telegdy, G | 4 |
| Bujdosó, E; Farkas, J; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
| Dmitrieva, IG; Gamaleia, AA; Gamaleia, NB; Kuz'mina, TI; Shostak, OA | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Araki, H; Choshi, T; Gomita, Y; Hibino, S; Jin, C; Kawasaki, H; Kawasaki, Y; Shibata, K; Suemaru, K | 1 |
| Baeyens, JM; Cendán, CM; Portillo-Salido, E; Pujalte, JM | 1 |
| Chen, LK; Guo, SL; Huang, HH; Lin, CJ; Sun, WZ | 1 |
| Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
| Belyaeva, YA; Dobryakova, YV; Dubynin, VA; Kamenskii, AA; Stovolosov, IS | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH | 1 |
| Baeyens, JM; Cendán, CM; Cobos, EJ; Del Pozo, E; Entrena, JM; Nieto, FR | 1 |
| Becejac, T; Blagaic, V; Boban Blagaic, A; Dubovecak, M; Jelovac, N; Radic, B; Sikiric, P; Stancic Rokotov, D; Turcic, P; Zemba, M | 1 |
| Dias, QM; Fais, RS; Petronilho, A; Prado, WA; Reis, GM | 1 |
| Jászberényi, M; Telegdy, G | 1 |
| Batisti, AP; Carlesso, MG; Donatello, N; dos Santos, AR; Emer, AA; Martins, DF; Mazzardo-Martins, L; Micke, GA; Piovezan, AP; Pizzolatti, MG; Venzke, D | 1 |
| Chae, Y; Enck, P; Lee, B; Lee, IS; Olausson, H; Park, HJ | 1 |
| Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K | 1 |
| Jaimez, R; Ochoa-Aguilar, A; Plancarte-Sánchez, R; Rodríguez, R; Sotomayor-Sobrino, MA; Ventura-Martinez, R | 1 |
| Currie, PJ; Hackenberg, TD; Morales, I; Pastor, R | 1 |
8 review(s) available for haloperidol and naloxone
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Overview of the progress in drug dependence studies--mainly focussing on psychic dependence].
Topics: Animals; Benzodiazepines; Haloperidol; Humans; Limbic System; Methadone; Naloxone; Receptors, Dopamine; Substance-Related Disorders | 1992 |
Opioid and catecholaminergic mechanisms of different types of analgesia.
Topics: Acetates; Acetic Acid; Acupuncture Therapy; Analgesia; Animals; Electric Stimulation; Electroshock; Endorphins; Formaldehyde; Haloperidol; Hot Temperature; Hydroxydopamines; Naloxone; Oxidopamine; Pain; Potassium Chloride; Propranolol; Rats; Reserpine; Sensory Thresholds | 1986 |
Catalepsy induced by body pinch: relation to stress-induced analgesia.
Topics: Analgesia; Animals; Apomorphine; Catalepsy; Endorphins; Haloperidol; Mice; Naloxone; Pain; Receptors, Dopamine; Stress, Physiological | 1986 |
The time course of excessive grooming after neuropeptide administration.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Brain Mapping; Cerebral Cortex; Cosyntropin; Dopamine; Drug Tolerance; Grooming; Haloperidol; Hippocampus; Injections, Intraventricular; Morphine; Naloxone; Rats; Substantia Nigra | 1983 |
Tuberoinfundibular dopamine neurons and the regulation of prolactin secretion.
Topics: Animals; Dopamine; Female; Haloperidol; Male; Morphine; Naloxone; Neurons; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Rats | 1981 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
2 trial(s) available for haloperidol and naloxone
| Article | Year |
|---|---|
Sleep pattern alterations by naloxone. Partial prevention by haloperidol.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Naloxone; Receptors, Dopamine; Sleep Stages | 1984 |
The effect of haloperidol and naloxone on excessive grooming behavior of cats.
Topics: Alopecia; Animals; Cat Diseases; Cats; Double-Blind Method; Female; Grooming; Haloperidol; Male; Naloxone; Stereotyped Behavior | 1994 |
234 other study(ies) available for haloperidol and naloxone
| Article | Year |
|---|---|
Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution | 1992 |
Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'- propenyl)-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand.
Topics: Binding Sites; Dopamine Agents; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Salicylamides; Stereoisomerism; Tetrahydronaphthalenes | 1993 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Methylated analogues of methyl (R)-4-(3,4-dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as highly potent kappa-receptor agonists: stereoselective synthesis, opioid-receptor affinity, receptor selectivity, and functio
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; Binding Sites; Brain; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Piperazines; Pyrrolidines; Rabbits; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2001 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Synthesis of bridged piperazines with sigma receptor affinity.
Topics: Cross-Linking Reagents; Molecular Structure; Piperazine; Piperazines; Receptors, sigma | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Conformationally constrained kappa receptor agonists: stereoselective synthesis and pharmacological evaluation of 6,8-diazabicyclo[3.2.2]nonane derivatives.
Topics: Animals; Azabicyclo Compounds; Cell Line; Guinea Pigs; Humans; In Vitro Techniques; Molecular Conformation; Radioligand Assay; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Blood-Brain Barrier; Brain; Endothelial Cells; Guinea Pigs; HEK293 Cells; Humans; Liver; Male; Mice; Models, Molecular; Pain Measurement; Permeability; Pyrrolidines; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship | 2014 |
Design and Synthesis of Enantiomerically Pure Decahydroquinoxalines as Potent and Selective κ-Opioid Receptor Agonists with Anti-Inflammatory Activity in Vivo.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis; Drug Design; Guinea Pigs; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Quinoxalines; Rats, Wistar; Receptors, Opioid, kappa; Skin | 2017 |
Development of Novel Quinoxaline-Based κ-Opioid Receptor Agonists for the Treatment of Neuroinflammation.
Topics: Animals; Antineoplastic Agents; Binding Sites; Encephalomyelitis, Autoimmune, Experimental; HEK293 Cells; Humans; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Docking Simulation; Protein Structure, Tertiary; Quinoxalines; Receptors, Opioid, kappa; Signal Transduction; Structure-Activity Relationship; Th1 Cells | 2019 |
Synthesis of 8-aminomorphans with high KOR affinity.
Topics: Molecular Conformation; Pyrrolidines; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship | 2022 |
Neurotransmitter receptor binding: regional distribution in human brain.
Topics: Alprenolol; Brain; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Haloperidol; Humans; Lysergic Acid Diethylamide; Naloxone; Neurotransmitter Agents; Quinuclidines; Receptors, Neurotransmitter; Serotonin | 1977 |
Haloperidol attenuation of morphine abstinence: synergistic effect of acute lithium administration.
Topics: Animals; Drug Synergism; Haloperidol; Humans; Lithium; Male; Methyltyrosines; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome | 1977 |
Evaluation of naloxone in laboratory tests predictive of clinical antipsychotic activity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Clozapine; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Mice; Naloxone; Rats; Schizophrenia; Species Specificity; Stereotyped Behavior | 1977 |
Increased binding of [3H]apomorphine in caudate membranes after dopamine pretreatment in vitro.
Topics: Animals; Apomorphine; Cattle; Caudate Nucleus; Dioxanes; Dopamine; Haloperidol; In Vitro Techniques; Membranes; Naloxone; Phenyl Ethers | 1978 |
Some considerations regarding the characterization and interpretation of neuropeptide-induced behavioral changes.
Topics: Animals; Behavior, Animal; Benzimidazoles; Dogs; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Injections, Intravenous; Injections, Intraventricular; Methadone; Mice; Morphine; Motor Activity; Naloxone; Peptides; Rats; Time Factors | 1978 |
The attenuation of delta 9-tetrahydrocannabinol and morphine of the quasi-morphine withdrawal syndrome in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Chlordiazepoxide; Dronabinol; Haloperidol; Humans; Male; Morphine; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome | 1979 |
Is morphine-induced catalepsy related to activation of dopaminergic neurones?
Topics: Animals; Apomorphine; Catalepsy; Dopamine; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Naloxone; Neurons; Rats; Stereotyped Behavior | 1978 |
Decrease in serum prolactin by naloxone: evidence against antidopamine and antipsychotic effects.
Topics: Animals; Haloperidol; Haplorhini; Humans; Macaca; Male; Methadone; Morphine; Naloxone; Opioid-Related Disorders; Prolactin; Psychotic Disorders; Receptors, Dopamine | 1979 |
Enkephalin-induced myoclonic twitches blocked by ergometrine and potentiated by haloperidol.
Topics: Animals; Drug Synergism; Endorphins; Enkephalins; Ergonovine; Female; Haloperidol; Male; Myoclonus; Naloxone; Rats; Time Factors | 1979 |
The potentiating effect of naloxone upon apomorphine-induced hyperthermia.
Topics: Animals; Apomorphine; Body Temperature; Cyproheptadine; Dextroamphetamine; Drug Synergism; Fenclonine; Haloperidol; Lysergic Acid Diethylamide; Male; Naloxone; Rabbits | 1977 |
Dopaminergic mechanisms of opiate actions in brain.
Topics: Analgesics; Animals; Brain; Dopamine; Drug Synergism; Drug Tolerance; Haloperidol; Humans; Levodopa; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Reaction Time; Synapses; Synaptic Transmission | 1975 |
Effects of antipsychotic drugs on action potential production in skeletal muscle. II. Haloperidol: nonspecific and opiate drug receptor mediated effects.
Topics: Action Potentials; Animals; Anura; Chlorpromazine; Electric Stimulation; Haloperidol; In Vitro Techniques; Muscles; Naloxone; Rana pipiens; Receptors, Opioid; Sodium; Time Factors | 1977 |
The involvement of dopaminergic neurotransmission in the inhibitory effect of morphine on caudate neurone activities.
Topics: Animals; Caudate Nucleus; Dopamine; Electric Stimulation; Haloperidol; Male; Microelectrodes; Morphine; Naloxone; Neurons; Pimozide; Rats; Substantia Nigra; Synaptic Transmission; Time Factors | 1977 |
Facilitatory effect of naloxone and involvement of specific ligand-opiate receptor system in the antinociceptive effects of non-opioid drugs.
Topics: Analgesics; Animals; Baclofen; Benperidol; Haloperidol; Levodopa; Male; Mice; Naloxone; Phosphodiesterase Inhibitors; Pimozide; Receptors, Opioid; Sympathomimetics | 1978 |
The effects of opiate agonist and antagonist on serum prolactin in primates: possible role for endorphins in prolactin regulation.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Endorphins; Haloperidol; Haplorhini; Macaca; Male; Morphine; Naloxone; Prolactin; Receptors, Opioid | 1979 |
Enhancement of morphine analgesia after acute and chronic haloperidol.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Morphine; Naloxone; Pain; Rats; Receptors, Opioid; Spiperone | 1979 |
Naloxone and haloperidol reduce grooming occurring as an aftereffect of novelty.
Topics: Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Grooming; Haloperidol; Male; Naloxone; Rats; Social Environment | 1979 |
Effect of naloxone, haloperidol and propranolol on cyclic 3',5'-adenosine monophosphate content of rat amygdala.
Topics: Amygdala; Animals; Caudate Nucleus; Cyclic AMP; Drug Interactions; Female; Haloperidol; Hippocampus; Hypothalamus; In Vitro Techniques; Naloxone; Nerve Tissue Proteins; Propranolol; Rats | 1979 |
A peptide-containing fraction in the urine of schizophrenic patients which stimulates opiate receptors and inhibits dopamine uptake.
Topics: Adult; Animals; Brain; Chromatography, Gel; Dopamine; Dopamine Antagonists; Drug Tolerance; Female; Haloperidol; Humans; Male; Motor Activity; Naloxone; Peptides; Phenoxybenzamine; Rats; Receptors, Opioid; Schizophrenia; Serotonin; Synaptosomes | 1979 |
Dopamine-mediated behavior produced by the enkephalin analogue FK 33-824.
Topics: Animals; Apomorphine; Chlorpromazine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Male; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid; Stereotyped Behavior | 1979 |
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat.
Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone | 1977 |
The anti-nociceptive effect of reserpine and haloperidol mediated by the nigro-striatal system: antagonism by naloxone.
Topics: Analgesics; Animals; Corpus Striatum; Female; Haloperidol; Morphine; Naloxone; Rats; Reaction Time; Reserpine; Substantia Nigra | 1979 |
Effect of morphine on the accumulation of DOPA after decarboxylase inhibition in the rat.
Topics: 4-Butyrolactone; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; DNA; Haloperidol; Male; Morphine; Naloxone; Rats; Receptors, Drug; Reserpine; Time Factors | 1979 |
Anti-nociceptive effect of morphine, opioid analgesics and haloperidol injected into the caudate nucleus of the rat.
Topics: Analgesics; Animals; Apomorphine; Caudate Nucleus; Female; Haloperidol; Injections; Male; Morphine; Naloxone; Narcotics; Rats | 1979 |
The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat.
Topics: Animals; Dopamine; Haloperidol; Male; Morphine; Motor Activity; Naloxone; Rats; Substantia Nigra; Tegmentum Mesencephali | 1979 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting | 1979 |
Neuroanatomical focus for morphine and enkephalin-induced hypermotility.
Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Enkephalins; Haloperidol; Humans; Hyperkinesis; Injections; Injections, Intraperitoneal; Male; Morphine; Naloxone; Olfactory Bulb; Oligopeptides; Rats; Stimulation, Chemical; Time Factors | 1977 |
Dopaminergic mediation of beta-endorphin-induced catalepsy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Catalepsy; Corpus Striatum; Dopamine; Drug Synergism; Endorphins; Haloperidol; Humans; Male; Naloxone; Rats | 1978 |
The antagonism by naloxone of agents that interact with dopaminergic neurones.
Topics: Animals; Brain; Buprenorphine; Dextroamphetamine; Dopamine; Haloperidol; Homovanillic Acid; Methyltyrosines; Morphine; Naloxone; Neurons; Norepinephrine; Rats | 1978 |
Effects of morphine on the serum prolactin levels of morphine-tolerant and nontolerant male rats and of the in vitro release of pituitary prolactin.
Topics: Animals; Apomorphine; Diphenhydramine; Dopamine; Drug Tolerance; Haloperidol; In Vitro Techniques; Male; Morphine; Naloxone; Pituitary Gland, Anterior; Prolactin; Rats | 1978 |
Enhanced naloxone potency and the development of narcotic tolerance.
Topics: Animals; Atropine; Biogenic Amines; Drug Tolerance; Haloperidol; Male; Mice; Morphine; Naloxone; Narcotics | 1979 |
Dyskinesias in monkeys: interaction of methamphetamine with prior methadone treatment.
Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methamphetamine; Naloxone; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Stereotyped Behavior | 1976 |
beta-Endorphin: endogenous opiate or neuroleptic?
Topics: Animals; Behavior, Animal; Brain; Endorphins; Haloperidol; Male; Motor Activity; Movement; Naloxone; Posture; Rats; Reflex | 1977 |
The effect of acute doses of buprenorphine on concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) in the rat forebrain [proceedings].
Topics: Animals; Brain; Cyclopropanes; Glycols; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Morphinans; Naloxone; Narcotic Antagonists; Phenylacetates; Rats | 1976 |
Fentanyl and apomorphine: asymmetrical generalization of discriminative stimulus properties.
Topics: Animals; Apomorphine; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Psychological; Haloperidol; Male; Naloxone; Rats; Receptors, Dopamine | 1976 |
Effects of fentanyl and droperidol on the dopamine metabolism of the rat striatum.
Topics: Animals; Catalepsy; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Haloperidol; Homovanillic Acid; Humans; Male; Naloxone; Rats | 1976 |
Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice.
Topics: Animals; Apomorphine; Brain; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Morphine Dependence; Motor Activity; Naloxone; Species Specificity; Substance Withdrawal Syndrome | 1976 |
Haloperidol binding to an opiate receptor site.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; In Vitro Techniques; Kinetics; Male; Morphine; Naloxone; Rats; Receptors, Drug; Sodium; Structure-Activity Relationship; Tritium | 1975 |
The effect of dopaminergic stimulation and blockade on the nociceptive and antinociceptive responses of mice.
Topics: Analgesics; Animals; Apomorphine; Depression, Chemical; Dopamine; Haloperidol; Levodopa; Male; Mice; Morphine; Naloxone; Pain; Pimozide; Reaction Time; Receptors, Drug; Stimulation, Chemical | 1975 |
Identification of opiate receptor binding in intact animals.
Topics: Animals; Binding Sites; Brain; Cerebellum; Cold Temperature; Corpus Striatum; Ether; Haloperidol; Male; Morphine; Nalorphine; Naloxone; Pentobarbital; Pimozide; Rats; Receptors, Drug; Sodium Chloride | 1975 |
Tetrahydrocannabinol-attenuated abstinence and induced rotation in morphine-dependent rats: possible involvement of dopamine.
Topics: Animals; Behavior; Cannabis; Dopamine; Dronabinol; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Promethazine; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1975 |
Stereotypy following acute administration of l-alpha-acetylmethadol (LAAM) in the rat.
Topics: Amphetamine; Animals; Apomorphine; Behavior; Drug Interactions; Haloperidol; Humans; Male; Methadone; Methadyl Acetate; Methyltyrosines; Naloxone; Rats; Stereotyped Behavior | 1975 |
The effects of receptor blockers on brain natriuretic peptide-32-induced action on passive avoidance behavior in rats.
Topics: Animals; Atropine; Avoidance Learning; Brain; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Naloxone; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Propranolol; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter | 1992 |
Long-term influence of d-amphetamine on mesolimbic brain-stimulation reward: comparison to chronic haloperidol and naloxone effects.
Topics: Animals; Dextroamphetamine; Discrimination Learning; Electric Stimulation; Haloperidol; Limbic System; Male; Naloxone; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome | 1992 |
Dopamine and endogenous opioid regulation of picrotoxin-induced locomotion in the ventral pallidum after dopamine depletion in the nucleus accumbens.
Topics: Animals; Dopamine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Globus Pallidus; Haloperidol; Male; Microinjections; Motor Activity; Naloxone; Nucleus Accumbens; Picrotoxin; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical | 1992 |
Naloxone or haloperidol but not yohimbine reverse apomorphine-induced respiratory depression.
Topics: Animals; Apomorphine; Dogs; Drug Interactions; Female; Haloperidol; Injections, Intravenous; Male; Naloxone; Respiratory Insufficiency; Vomiting; Yohimbine | 1992 |
Mechanisms for the stimulatory effects of opioidergic and serotonergic input signals on prolactin in pregnant rats.
Topics: alpha-Methyltyrosine; Animals; beta-Endorphin; Bromocriptine; Circadian Rhythm; Dopamine; Female; Haloperidol; Ketamine; Methyltyrosines; Naloxone; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1992 |
Alpha 2-adrenoceptor- and D2-dopamine receptor-mediated analgesic response of B-HT 920.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Azepines; Dopamine Agents; Female; Haloperidol; Male; Mice; Naloxone; Pain Measurement; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Dopamine D2 | 1991 |
Naloxone prevents and blocks the emergence of neuroleptic-mediated oral stereotypic behaviors.
Topics: Animals; Antipsychotic Agents; Dextroamphetamine; Dyskinesia, Drug-Induced; Haloperidol; Male; Nalidixic Acid; Naloxone; Naphthyridines; Rats; Rats, Inbred F344; Stereotyped Behavior | 1991 |
[The neurochemical mechanisms of the inhibitory influences of stimulation of the central gray substance on the high-threshold reflex activity of the reticular formation].
Topics: Animals; Dopamine; Haloperidol; Male; Mesencephalon; Methysergide; Microinjections; Naloxone; Neural Inhibition; Neurotransmitter Agents; Rats; Reflex; Reticular Formation; Serotonin | 1991 |
Dopamine receptor antagonists block the effect of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) on the opiate form of footshock-induced analgesia.
Topics: Amino Acid Sequence; Animals; Benzazepines; Dopamine Antagonists; Drug Synergism; Foot; Haloperidol; Hot Temperature; Male; Molecular Sequence Data; MSH Release-Inhibiting Hormone; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Transcutaneous Electric Nerve Stimulation | 1991 |
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Topics: Amnesia; Animals; Atrial Natriuretic Factor; Atropine; Avoidance Learning; Bicuculline; Electroshock; Haloperidol; Male; Memory; Methysergide; Naloxone; Phenoxybenzamine; Propranolol; Rats | 1991 |
Dopaminergic transmission in the hypothalamic arcuate nucleus to produce acupuncture analgesia in correlation with the pituitary gland.
Topics: Acupuncture Analgesia; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Denervation; Dopamine; Electric Stimulation; Haloperidol; Hypothalamo-Hypophyseal System; Male; Microinjections; Morphine; Naloxone; Neurons; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Transmission | 1991 |
Opioid and non-opioid central cardiovascular effects of ketamine.
Topics: Animals; Blood Pressure; Cats; Cisterna Magna; Dose-Response Relationship, Drug; Haloperidol; Heart Rate; Hemodynamics; Injections; Ketamine; Naloxone; Phencyclidine; Pimozide; Receptors, Opioid; Receptors, sigma | 1990 |
Inhibition of neurotensin-induced miosis by blockade of ocular dopamine pathways.
Topics: Animals; Atropine; Autonomic Nervous System; Desipramine; Dopamine; Dopamine Antagonists; Eye; Haloperidol; Hydroxydopamines; Iris; Miosis; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nerve Endings; Neurotensin; Neurotransmitter Agents; Oxidopamine; Rabbits; Receptors, Opioid, mu | 1990 |
Effects of morphine on memory: interactions with naloxone, propranolol and haloperidol.
Topics: Animals; Dopamine; Haloperidol; Male; Memory; Mice; Mice, Inbred ICR; Morphine; Naloxone; Propranolol; Sympathetic Nervous System | 1991 |
The ambulation-increasing effect of buprenorphine in mice: comparison with the effect of morphine.
Topics: Animals; Buprenorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Morphine; Naloxone; Pilocarpine; Scopolamine | 1991 |
[The sensitivity of the blood lymphocytes in stomach cancer patients to met-enkephalin, dopamine and serotonin].
Topics: Adult; Aged; Chemoreceptor Cells; Dopamine; Enkephalin, Methionine; Female; Haloperidol; Humans; Leukocyte Adherence Inhibition Test; Lymphocytes; Male; Methysergide; Middle Aged; Naloxone; Neoplasm Staging; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Serotonin; Stomach Neoplasms | 1990 |
Effect of selective sigma ligands on duodenal alkaline secretion in the rat.
Topics: Animals; Atropine; Bicarbonates; Dose-Response Relationship, Drug; Duodenum; Guanidines; Haloperidol; Injections, Intravenous; Intestinal Mucosa; Intestinal Secretions; Male; Naloxone; Phenazocine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Yohimbine | 1990 |
Ontogeny of the endorphinergic and dopaminergic modulation on the immobility reflex elicited by clamping in rats.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Endorphins; Female; Haloperidol; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reflex | 1990 |
Potentiating effect of morphine upon d-methamphetamine-induced hyperthermia in mice. Effects of naloxone and haloperidol.
Topics: Animals; Body Temperature Regulation; Drug Synergism; Fever; Haloperidol; Male; Methamphetamine; Mice; Morphine; Motor Activity; Naloxone | 1990 |
The effect of gamma-type endorphins on alpha-MSH release in the rat.
Topics: Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; gamma-Endorphin; Haloperidol; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Naloxone; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains | 1985 |
Grooming behavior induced by substance P.
Topics: Animals; Dose-Response Relationship, Drug; Grooming; Haloperidol; Injections, Intraventricular; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains; Substance P | 1988 |
Developmental changes in FSH secretion induced by 5-hydroxytryptophan, naloxone and haloperidol in male and female rats.
Topics: 5-Hydroxytryptophan; Aging; Animals; Female; Follicle Stimulating Hormone; Haloperidol; Male; Naloxone; Rats; Rats, Inbred Strains | 1989 |
Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Diencephalon; Fentanyl; Haloperidol; Humans; In Vitro Techniques; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female; Gastrointestinal Motility; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Naloxone; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Sincalide; Vomiting | 1989 |
Role of dopaminergic system in opioid-induced cardiovascular responses in dogs.
Topics: Animals; Blood Pressure; Central Nervous System; Dogs; Female; Haloperidol; Male; Morphine; Naloxone; Receptors, Dopamine | 1989 |
ACTH-induced grooming behaviors and body temperature. Temporal effects of neurotensin, naloxone, and haloperidol.
Topics: Adrenocorticotropic Hormone; Animal Husbandry; Animals; Behavior, Animal; Body Temperature; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Naloxone; Neurotensin; Sodium Chloride; Time Factors | 1988 |
Comparison of bombesin-, ACTH-, and beta-endorphin-induced grooming. Antagonism by haloperidol, naloxone, and neurotensin.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Bombesin; Brain; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Naloxone; Neurotensin | 1988 |
A role for histamine and histamine H2-receptors in non-opiate footshock-induced analgesia.
Topics: Animals; Cimetidine; Electroshock; Haloperidol; Histamine; Histamine H2 Antagonists; Male; Naloxone; Pain; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H2 | 1985 |
Effects of morphine and neuroleptics on wet-dog shaking behavior elicited by hippocampal stimulation in rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, Drug; Electric Stimulation; Haloperidol; Hippocampus; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1985 |
Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus.
Topics: Animals; Atropine; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Haloperidol; Injections, Spinal; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Reflex; Reticular Formation; Spinal Cord; Yohimbine | 1986 |
Involvement of opioid receptors in phencyclidine-induced enhancement of brain histamine turnover in mice.
Topics: Analgesics, Opioid; Animals; Brain; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Haloperidol; Histamine; Histidine Decarboxylase; Ketamine; Male; Methylhistidines; Mice; Naloxone; Pargyline; Phenazocine; Phencyclidine; Receptors, Opioid | 1987 |
Stress-induced insomnia: opioid-dopamine interactions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Appetite Depressants; Benzazepines; gamma-Aminobutyric Acid; Haloperidol; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Sleep, REM; Stress, Psychological; Sulpiride | 1987 |
Excessive grooming induced by somatostatin or its analog SMS 201-995.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Grooming; Haloperidol; Injections, Intraventricular; Male; Naloxone; Neurotensin; Octreotide; Rats; Rats, Inbred Strains; Receptors, Opioid; Somatostatin | 1987 |
Evidence for dopaminergic and opioid involvement in the regulation of locomotor activity in the land crab Gecarcinus lateralis.
Topics: Animals; Brachyura; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Haloperidol; Motor Activity; Naloxone; Narcotics | 1988 |
Enhancement by haloperidol of the locomotor response induced by naloxone in morphine-treated guinea pigs.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Haloperidol; Male; Morphine; Motor Activity; Naloxone; Substance Withdrawal Syndrome; Time Factors | 1989 |
beta-Endorphin involvement in the antidopaminergic effect of caerulein.
Topics: Amphetamine; Animals; beta-Endorphin; Ceruletide; Endorphins; Haloperidol; Hypophysectomy; Injections, Intraventricular; Male; Motor Activity; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sincalide | 1986 |
The kappa opioid receptor and food intake.
Topics: Animals; Benzodiazepines; Benzomorphans; Butorphanol; Cyclazocine; Diprenorphine; Eating; Ethylketocyclazocine; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Time Factors | 1985 |
The influence of neurotensin, naloxone, and haloperidol on elements of excessive grooming behavior induced by ACTH.
Topics: Adrenocorticotropic Hormone; Animals; Grooming; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains | 1986 |
(+)- and (-)-N-allylnormetazocine binding sites in mouse brain: in vitro and in vivo characterization and regional distribution.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Ethylketocyclazocine; Haloperidol; In Vitro Techniques; Mice; Naloxone; Phenazocine; Phencyclidine; Receptors, Opioid; Receptors, sigma; Stereoisomerism | 1987 |
Changes in naloxone and haloperidol effects during the development of captivity-induced jumping stereotypy in bank voles.
Topics: Aging; Animals; Arvicolinae; Haloperidol; Naloxone; Stereotyped Behavior | 1988 |
Opioid modulation of thyrotropin releasing hormone induced prolactin secretion.
Topics: alpha-Methyltyrosine; Animals; Endorphins; Haloperidol; Male; Methyltyrosines; Naloxone; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1987 |
[Interaction of opioid peptides and the dopaminergic system in the myenteric plexus of the guniea pig ileum].
Topics: Animals; Apomorphine; Bromocriptine; Drug Interactions; Endorphins; Guinea Pigs; Haloperidol; Hydroxydopamines; Ileum; In Vitro Techniques; Myenteric Plexus; Naloxone; Oxidopamine; Receptors, Dopamine | 1987 |
Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward.
Topics: Animals; Catecholamines; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Haloperidol; Male; Mesencephalon; Naloxone; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1988 |
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
[Antagonism of caerulein, a CCK-8 receptor agonist, to the behavioral effects of ketamine in mice and rats].
Topics: Amnesia; Animals; Ataxia; Behavior, Animal; Ceruletide; Haloperidol; Ketamine; Male; Mice; Motor Activity; Naloxone; Rats; Receptors, Cholecystokinin; Stereotyped Behavior | 1988 |
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea Pigs; Haloperidol; Lisuride; Morphine; Myoclonus; Naloxone; Scopolamine; Tremorine | 1986 |
Neurochemical and behavioral effects of corticotropin-releasing factor in the ventral tegmental area of the rat.
Topics: Animals; Corticotropin-Releasing Hormone; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Haloperidol; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1987 |
Behavioral evidence for the involvement of endogenous opioids in the interaction between cholecystokinin and brain dopamine systems.
Topics: Animals; Apomorphine; Dopamine; Endorphins; Haloperidol; Male; Motor Activity; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sincalide | 1987 |
Mechanographic analysis of muscle rigidity after morphine and haloperidol: a new methodological approach.
Topics: Animals; Haloperidol; Male; Morphine; Muscle Rigidity; Muscle Tonus; Naloxone; Rats; Rats, Inbred Strains | 1987 |
Oxytocin potently enhances novelty-induced grooming behavior in the rat.
Topics: Animals; Female; Grooming; Haloperidol; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Oxytocin; Rats; Rats, Inbred Strains; Sex Characteristics; Time Factors | 1986 |
On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats.
Topics: Animals; Drug Tolerance; Haloperidol; Male; Morphine; Motor Activity; Muscle Rigidity; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Time Factors | 1986 |
Dissociated effects of apomorphine on various nociceptive responses in mice.
Topics: Analgesics; Animals; Apomorphine; Body Temperature; Domperidone; Dopamine; Haloperidol; Male; Mice; Naloxone; Pain Measurement; Sulpiride | 1986 |
Selective regional effect of various neuroactive drugs on bromocriptine concentration in the brain of rats.
Topics: Amantadine; Animals; Biperiden; Brain Chemistry; Bromocriptine; Carbidopa; Diazepam; Haloperidol; Levodopa; Methysergide; Naloxone; Rats | 1986 |
[Effect on morphine hyperthermia of dopaminergic agents].
Topics: Animals; Apomorphine; Body Temperature; Bromocriptine; Drug Interactions; Fever; Haloperidol; Male; Methotrimeprazine; Morphine; Naloxone; Rats; Rats, Inbred Strains; Rectum; Time Factors | 1985 |
Opiate-androgen interactions in drug-induced yawning and penile erections in the rat.
Topics: Animals; Dihydrotestosterone; Drug Interactions; Endorphins; Haloperidol; Male; Morphine; Naloxone; Orchiectomy; Penis; Rats; Rats, Inbred Strains; Reflex; Testosterone | 1986 |
Stereoselective behavioral effects of N-allylnormetazocine in pigeons and squirrel monkeys.
Topics: Animals; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Morphine; Naloxone; Phenazocine; Phencyclidine; Reinforcement Schedule; Saimiri; Stereoisomerism | 1985 |
A dopaminergic receptor modulates catecholamine release from the cat adrenal gland.
Topics: Adrenal Glands; Adrenal Medulla; Animals; Apomorphine; Benzamides; Catecholamines; Cats; Dopamine; Female; Haloperidol; Male; Naloxone; Nicotine; Phentolamine; Receptors, Dopamine | 1985 |
Neurotensin diminishes grooming and stimulates paper shredding behavior induced by water immersion of rats.
Topics: Animals; Grooming; Haloperidol; Humans; Immersion; Injections, Intraventricular; Male; Naloxone; Neurotensin; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1985 |
Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs.
Topics: Animals; Body Weight; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Stereoisomerism; Substance Withdrawal Syndrome | 1985 |
Effects of haloperidol on morphine-induced antinociception morphine tolerance and withdrawal in hyperprolactinaemic rats.
Topics: Animals; Drug Tolerance; Haloperidol; Male; Morphine; Naloxone; Nociceptors; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome | 1985 |
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Chemical; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Pentobarbital; Phenoxybenzamine; Phentolamine; Promethazine; Propranolol; Rats; Substance Withdrawal Syndrome; Time Factors | 1974 |
Morphine physical dependence in the dog.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dogs; Dose-Response Relationship, Drug; Haloperidol; Hot Temperature; Humans; Morphinans; Morphine; Morphine Dependence; Naloxone; Propranolol; Pulse; Pupil; Reflex; Respiration; Skin; Substance Withdrawal Syndrome; Time Factors | 1974 |
Differential antagonism by naloxone of inhibitory effects of haloperidol and morphine on brain self-stimulation.
Topics: Animals; Behavior, Animal; Blepharoptosis; Brain; Catalepsy; Catatonia; Electric Stimulation; Electrodes, Implanted; Exophthalmos; Haloperidol; Humans; Hypothalamus; Male; Morphine; Naloxone; Rats; Self Stimulation | 1974 |
Prenatal haloperidol alters striatal dopamine and opiate receptors.
Topics: Animals; Corpus Striatum; Female; Haloperidol; Maternal-Fetal Exchange; Naloxone; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Spiperone | 1984 |
Interaction of dopamine receptor ligands with subtypes of the opiate receptor.
Topics: Animals; Binding, Competitive; Brain; Bromocriptine; Dopamine Antagonists; Drug Interactions; Haloperidol; In Vitro Techniques; Ligands; Male; Membranes; Metoclopramide; Naloxone; Pimozide; Prochlorperazine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Tritium | 1984 |
K+-evoked release of met-enkephalin from rat striatum in vitro: effect of putative neurotransmitters and morphine.
Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Haloperidol; Hydroxydopamines; Male; Morphine; Naloxone; Neurotransmitter Agents; Potassium; Radioimmunoassay; Rats | 1980 |
Pharmacologic study of respiratory afterdischarge.
Topics: 5,7-Dihydroxytryptamine; Animals; Carotid Body; Cats; Endorphins; Evoked Potentials; Fenclonine; Haloperidol; Methyltyrosines; Methysergide; Naloxone; Neurotransmitter Agents; Phrenic Nerve; Respiration; Respiratory Center | 1981 |
Suckling behavior in neonatal rats: psychopharmacological investigations.
Topics: Animals; Animals, Newborn; Haloperidol; Metergoline; Methiothepin; Methysergide; Naloxone; Neurotransmitter Agents; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Scopolamine; Sucking Behavior | 1982 |
Bromperidol, a new butyrophenone neuroleptic: a review.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Biotransformation; Brain; Chlorpromazine; Dogs; Female; Half-Life; Haloperidol; Male; Mice; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid | 1982 |
Haloperidol treatment increases the biosynthesis and release of endorphins in guinea-pig ileum.
Topics: Animals; Cycloheximide; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Female; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Naloxone; Receptors, Dopamine | 1984 |
Neurotransmitter-blocking agents influence antinociceptive effects of carbamazepine, baclofen, pentazocine and morphine on bradykinin-induced trigeminal pain.
Topics: Analgesics; Animals; Atropine; Baclofen; Bicuculline; Bradykinin; Carbamazepine; Haloperidol; Male; Methysergide; Morphine; Naloxone; Neurotransmitter Agents; Pentazocine; Rats; Rats, Inbred Strains; Sympatholytics; Trigeminal Neuralgia; Trigeminal Nucleus, Spinal | 1984 |
Feeding systems in Chinese hamsters.
Topics: Animals; Brain; Calcitonin; Circadian Rhythm; Cricetinae; Cyclazocine; Diabetes Mellitus; Dynorphins; Eating; Endorphins; Ethylketocyclazocine; Feeding Behavior; Haloperidol; Mesocricetus; Naloxone; Peptide Fragments; Phenazocine; Sincalide; Starvation | 1984 |
Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Flumazenil; Haloperidol; Male; Naloxone; Rats; Receptors, Drug; Reinforcement Schedule; Self Administration | 1984 |
Kinetics of brain receptor binding inhibition by endogenous macromolecular substances [proceedings].
Topics: Animals; Apomorphine; Brain; Fentanyl; Haloperidol; Kinetics; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Receptors, Serotonin | 1980 |
Further evidence for the neuroleptic-like activity of gamma-endorphin.
Topics: Animals; Antipsychotic Agents; Bromocriptine; Dextroamphetamine; Endorphins; gamma-Endorphin; Haloperidol; Humans; Kinetics; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1981 |
The influence of beta-LPH fragments on alpha-MSH release: the involvement of a dopaminergic system.
Topics: alpha-Endorphin; Animals; Apomorphine; beta-Endorphin; Brain Chemistry; Dopamine; Endorphins; gamma-Endorphin; Haloperidol; Male; Melanocyte-Stimulating Hormones; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains | 1981 |
Interaction of opiates with dopamine receptors: receptor binding and behavioral assays.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butaclamol; Dibenzocycloheptenes; Haloperidol; Kinetics; Male; Methadone; Morphine; Naloxone; Rats; Receptors, Dopamine; Spiperone | 1982 |
The effect of neonatal treatment of mice with opioid and dopaminergic agents on the late responsiveness of vasa deferentia to opioids in vitro.
Topics: Animals; Animals, Newborn; Dopamine; Endorphins; Enkephalin, Methionine; Haloperidol; Male; Mice; Morphine; Naloxone; Piribedil; Sulpiride; Time Factors; Vas Deferens | 1984 |
Memory facilitation by naloxone is due to release of dopaminergic and beta-adrenergic systems from tonic inhibition.
Topics: Animals; Dextroamphetamine; Dopamine; Drug Interactions; Female; Haloperidol; Memory; Naloxone; Neural Inhibition; Nicotine; Phenoxybenzamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tolazoline | 1980 |
Effects of cholecystokinin octapeptide on striatal dopamine metabolism and on apomorphine-induced stereotyped cage-climbing in mice.
Topics: alpha-Methyltyrosine; Animals; Apomorphine; Cholecystokinin; Corpus Striatum; Dopamine; Drug Interactions; Haloperidol; Humans; Male; Methyltyrosines; Mice; Naloxone; Receptors, Dopamine; Sincalide; Stereotyped Behavior | 1981 |
Peptidergic regulation of stress-induced eating.
Topics: Animals; Appetite Depressants; Atropine; Bombesin; Carbachol; Cholecystokinin; Enkephalin, Methionine; Enkephalins; Feeding Behavior; Haloperidol; Humans; Isoproterenol; Male; Muscimol; Naloxone; Norepinephrine; Peptide Fragments; Peptides; Phentolamine; Quipazine; Rats; Rats, Inbred Strains; Sincalide; Stress, Psychological | 1982 |
Involvement of both opiate and catecholaminergic receptors in the behavioural excitation provoked by thyrotropin-releasing hormone: comparisons with amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Haloperidol; Humans; Hyperkinesis; Male; Naloxone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Thyrotropin-Releasing Hormone; Yohimbine | 1983 |
ACTH-(1-24) and RX 336-M induce excessive grooming in rats through different mechanisms.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Codeine; Cosyntropin; Drug Tolerance; Grooming; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Both dopaminergic and adrenergic receptors in the brain are involved in the behavioural excitation induced by dibutyryl 3',5'-adenosine monophosphate and aminophylline in the rat.
Topics: Aminophylline; Animals; Behavior, Animal; Brain; Bucladesine; Haloperidol; Injections, Intraventricular; Male; Naloxone; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Yohimbine | 1984 |
Phencyclidine-induced inhibition of striatal acetylcholine release: comparisons with mu, kappa, and sigma opiate agonists.
Topics: Acetylcholine; Animals; Corpus Striatum; Cyclazocine; Ethylketocyclazocine; Haloperidol; Male; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains | 1984 |
Effects of naloxone on methamphetamine and apomorphine stereotypy and on haloperidol catalepsy in rats.
Topics: Animals; Apomorphine; Catalepsy; Haloperidol; Humans; Male; Methamphetamine; Naloxone; Rats; Stereotyped Behavior | 1984 |
Glucagon and insulin secretion and their biological activities in hypothermic rats.
Topics: Animals; Arginine; Atropine; Blood Glucose; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Catecholamines; Glucagon; Haloperidol; Hydrogen-Ion Concentration; Hypothermia, Induced; Insulin; Insulin Secretion; Liver Circulation; Male; Naloxone; Oxygen; Partial Pressure; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1984 |
Effects of phencyclidine, haloperidol, and naloxone on fixed-interval performance in rats.
Topics: Animals; Conditioning, Operant; Haloperidol; Male; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Reinforcement Schedule | 1984 |
Comparison of the effects of central acting drugs on prolactin release in young and old male rats.
Topics: Age Factors; Animals; Haloperidol; Male; Methyldopa; Morphine; Naloxone; Prolactin; Quinolines; Quipazine; Radioimmunoassay; Rats | 1981 |
Amphetamine-induced analgesia does not involve brain opioids.
Topics: Amphetamine; Analgesics; Animals; Brain; Endorphins; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time | 1984 |
[Pharmacological action of eptazocine (l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine). Effects of eptazocine on spontaneous movements].
Topics: Analgesics; Animals; Apomorphine; Cyclazocine; Disulfiram; Haloperidol; Male; Morphine; Movement; Naloxone; Pentazocine; Rats; Rats, Inbred Strains | 1983 |
Effect of naloxone on a quickly learned conditioned suppression in rats following cessation of chronic haloperidol treatment.
Topics: Animals; Conditioning, Operant; Drug Antagonism; Electroshock; Haloperidol; Learning; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains | 1983 |
Postictal prolactin elevations in rats.
Topics: Animals; Atropine; Electric Stimulation; Haloperidol; Male; Naloxone; Prolactin; Rats; Rats, Inbred Strains; Seizures | 1983 |
[Effects of haloperidol pretreatment on the release of enkephalins by electrical stimulation in the isolated guinea pig ileum].
Topics: Animals; Electric Stimulation; Enkephalins; Female; Guinea Pigs; Haloperidol; Ileum; Male; Naloxone | 1983 |
Central effects of dopamine on vasopressin release in the normally hydrated and water-loaded rat.
Topics: Animals; Diuresis; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Microinjections; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Vasopressins; Water | 1984 |
Interactions of naloxone and haloperidol with phencyclidine: effects on milk intake.
Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Haloperidol; Male; Milk; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains | 1984 |
Naloxone-induced jumping activity in morphine-dependent mice: a pharmacological study on the role of DA2 receptors.
Topics: Animals; Drug Tolerance; Haloperidol; Lisuride; Male; Mice; Morphine; Motor Activity; Naloxone; Receptors, Dopamine; Tiapamil Hydrochloride | 1984 |
Effects of naloxone and naltrexone on drug-induced hypothermia in mice.
Topics: Animals; Apomorphine; Body Temperature; Body Temperature Regulation; Dopamine; Haloperidol; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotics; Pentobarbital | 1984 |
Dexamethasone: a potent blocker for radiation-induced taste aversion in rats.
Topics: Animals; Aspirin; Avoidance Learning; Cimetidine; Conditioning, Classical; Dexamethasone; Dimethyl Sulfoxide; Domperidone; Dose-Response Relationship, Radiation; Gamma Rays; Haloperidol; Insulin; Male; Naloxone; Rats; Rats, Inbred Strains; Taste | 1982 |
The role of the nucleus accumbens and nigrostriatum in enkephalin-induced myoclonus.
Topics: Animals; Brain; Corpus Striatum; Electroencephalography; Electromyography; Enkephalins; Epilepsies, Myoclonic; Haloperidol; Male; Naloxone; Nucleus Accumbens; Rats; Septal Nuclei; Substantia Nigra | 1980 |
Long-term application of haloperidol: effects on dopamine and acetylcholine receptors.
Topics: 4-Butyrolactone; Animals; Benztropine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Haloperidol; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Time Factors | 1981 |
Influence of low doses of naloxone on pituitary secretion in man.
Topics: Adult; Female; Haloperidol; Humans; Male; Naloxone; Pituitary Gland; Pituitary Hormones; Prolactin; Thyrotropin-Releasing Hormone; Time Factors | 1982 |
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Sulpiride | 1982 |
Induction of wet-dog shakes by intracerebral 'acid' TRH in rats.
Topics: Animals; Apomorphine; Cyproheptadine; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Movement Disorders; Naloxone; Phentolamine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1980 |
Catecholamine mechanisms in the stimulation of mouse locomotor activity by nitrous oxide and morphine.
Topics: alpha-Methyltyrosine; Animals; Catecholamines; Haloperidol; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Naloxone; Nitrous Oxide | 1983 |
Peptidergic control of insulin-induced feeding.
Topics: Animals; Atropine; Blood Glucose; Bombesin; Cholecystokinin; Feeding Behavior; Haloperidol; Insulin; Male; Naloxone; Peptides; Rats; Rats, Inbred Strains | 1981 |
The role of dopaminergic mechanisms in naloxone-induced inhibition of apomorphine-induced stereotyped behavior.
Topics: Animals; Apomorphine; Behavior; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Humans; Male; Naloxone; Rats; Stereotyped Behavior; Time Factors | 1980 |
Reduction in the number of serotonin receptors in the brainstem of morphine dependent rats: relation to blockade of naloxone precipitated jumping by serotonin agonists.
Topics: Animals; Behavior, Animal; Brain Stem; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Piperazines; Propranolol; Quipazine; Rats; Receptors, Serotonin; Serotonin; Substance Withdrawal Syndrome | 1980 |
Involvement of caudate nucleus, amygdala or reticular formation in neuroleptic and narcotic catalepsy.
Topics: Amygdala; Animals; Catalepsy; Caudate Nucleus; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Naloxone; Phentolamine; Rats; Reticular Formation | 1981 |
Postictal behavioral arrest in the rat: "catalepsy" or "catatonia"?
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Catatonia; Electric Stimulation; Female; Haloperidol; Humans; Naloxone; Rats; Seizures | 1981 |
Differential cataleptogenic and antistereotypic effects of caerulein and haloperidol.
Topics: Animals; Catalepsy; Ceruletide; Drug Interactions; Haloperidol; Humans; Male; Methylphenidate; Mice; Naloxone; Stereotyped Behavior | 1981 |
Lack of effect of choline and narcotic antagonists upon apomorphine discrimination.
Topics: Animals; Apomorphine; Choline; Discrimination Learning; Haloperidol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Dopamine | 1980 |
Muscimol induced feeding: a model to study the hypothalamic regulation of appetite.
Topics: Animals; Appetite; Atropine; Calcitonin; Dose-Response Relationship, Drug; Eating; Haloperidol; Hypothalamus; Male; Models, Biological; Muscimol; Naloxone; Oxazoles; Rats; Rats, Inbred Strains | 1981 |
Self-administration of clonidine by the rat.
Topics: Animals; Azaperone; Clonidine; Fentanyl; Haloperidol; Infusions, Parenteral; Male; Muridae; Naloxone; Reinforcement Schedule; Self Administration | 1981 |
Failure of naloxone to prevent the emetic activity of apomorphine in dogs.
Topics: Animals; Apomorphine; Dogs; Droperidol; Female; Fentanyl; Haloperidol; Injections, Intravenous; Male; Naloxone; Time Factors; Vomiting | 1981 |
beta-Endorphin and met-enkephalins: their distribution, modulation by estrogens and haloperidol, and role in neuroendocrine control.
Topics: Animals; Brain; Brain Chemistry; Castration; Endorphins; Enkephalins; Estrogens; Female; Growth Hormone; Haloperidol; Male; Naloxone; Prolactin; Rats; Secretory Rate | 1980 |
On the mechanism of morphine action on rat striatal dopamine metabolsim.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Haloperidol; In Vitro Techniques; Morphine; Naloxone; Rats | 1980 |
Selective inhibition of mesolimbic behavioral supersensitivity by naloxone.
Topics: Animals; Behavior, Animal; Dopamine; Haloperidol; Limbic System; Male; Morphine; Naloxone; Rats; Self Stimulation | 1980 |
Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Daunorubicin; Haloperidol; Humans; Hydrogen-Ion Concentration; Ketones; Kinetics; Liver; Naloxone; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pharmaceutical Preparations | 1995 |
Sigma antagonists potentiate opioid analgesia in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Drug Synergism; Haloperidol; Morphine; Naloxone; Narcotics; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sulpiride | 1995 |
Interaction between discriminative stimulus effects of cocaine and morphine.
Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred F344; Synaptic Transmission | 1995 |
Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys.
Topics: Animals; Behavior, Animal; Buprenorphine; Butorphanol; Haloperidol; Imipramine; Macaca fascicularis; Male; Morphine; Morphine Dependence; Naloxone; Psychotropic Drugs; Substance Withdrawal Syndrome | 1994 |
Altered N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine is mediated by sigma activity.
Topics: Animals; Behavior, Animal; Haloperidol; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Naloxone; Receptors, sigma; Spinal Cord | 1995 |
Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens.
Topics: Action Potentials; Animals; Dopamine; Electric Stimulation; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Naloxone; Neurons; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1993 |
Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells.
Topics: Animals; Antipsychotic Agents; Brain Neoplasms; Cricetinae; Electrophysiology; Haloperidol; Ligands; Membrane Potentials; Mice; Naloxone; Neuroblastoma; Potassium Channels; Receptors, sigma; Remoxipride; Tumor Cells, Cultured | 1994 |
[Effect of agonists of opioid receptor on coronary arterial strips in porcine].
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Coronary Vessels; Fentanyl; Haloperidol; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Pyrrolidines; Receptors, Opioid; Swine | 1994 |
Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit.
Topics: Animals; Behavior, Animal; beta-Endorphin; Electroencephalography; Endorphins; Haloperidol; Injections, Intraventricular; Male; Naloxone; Peptide Fragments; Rabbits; Seizures | 1994 |
Voluntary oral morphine self-administration in rats: effect of haloperidol or ondansetron.
Topics: Animals; Behavior, Animal; Defecation; Haloperidol; Injections, Intramuscular; Male; Morphine; Morphine Dependence; Naloxone; Ondansetron; Quinine; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome | 1994 |
Morphine-induced hyperactivity in rats--a rebound effect?
Topics: Animals; Haloperidol; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Wistar; Stereotyped Behavior; Stimulation, Chemical | 1993 |
Effects of chronic naloxone administration on vacuous chewing movements and catalepsy in rats treated with long-term haloperidol decanoate.
Topics: Animals; Anti-Dyskinesia Agents; Catalepsy; Dyskinesia, Drug-Induced; Grooming; Haloperidol; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome | 1995 |
Sigma binding in a human neuroblastoma cell line.
Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Binding, Competitive; Brain; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Haloperidol; Humans; Kinetics; Morphine; Naloxone; Neuroblastoma; Pentazocine; Phosphatidylinositols; Receptors, Opioid; Receptors, sigma; Trypsin; Tumor Cells, Cultured | 1996 |
Nociceptin stimulates locomotion and exploratory behaviour in mice.
Topics: Animals; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Exploratory Behavior; Haloperidol; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; Stimulation, Chemical | 1996 |
Naloxone-sensitive, haloperidol-sensitive, [3H](+)SKF-10047-binding protein partially purified from rat liver and rat brain membranes: an opioid/sigma receptor?
Topics: Animals; Antipsychotic Agents; Brain; Haloperidol; Liver; Naloxone; Phenazocine; Radioligand Assay; Rats; Receptors, Opioid | 1997 |
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine | 1997 |
Effect of prior nicotine treatment on drug induced changes in serum LH concentrations in rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Gonadotropin-Releasing Hormone; Haloperidol; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1997 |
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists; Electric Stimulation; Haloperidol; Hypothalamic Area, Lateral; Male; Mecamylamine; Methysergide; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists | 1996 |
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA Antagonists; Haloperidol; Injections, Intraventricular; Male; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists; Sincalide | 1997 |
Mazindol and lidocaine are antinociceptives in the mouse formalin model: involvement of dopamine receptor.
Topics: Anesthetics, Local; Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; Lidocaine; Male; Mazindol; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Dopamine; Receptors, Opioid | 1997 |
Mechanisms of melatonin inhibition of neurohypophysial hormone release from the rat hypothalamus in vitro.
Topics: Animals; Atenolol; Atropine; Haloperidol; Hypothalamus; Ibuprofen; In Vitro Techniques; Male; Mecamylamine; Melatonin; Naloxone; Oxytocin; Phentolamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Reproducibility of Results; Vasopressins | 1998 |
Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.
Topics: Adult; Anti-Dyskinesia Agents; Basal Ganglia; Brain Ischemia; Coma; Corpus Striatum; Drug Overdose; Globus Pallidus; Haloperidol; Heroin; Humans; Magnetic Resonance Imaging; Male; Movement Disorders; Naloxone; Narcotic Antagonists; Substance Abuse, Intravenous; Tomography, X-Ray Computed | 1997 |
Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism.
Topics: Animals; Benzazepines; Clonidine; Cognition Disorders; Dopamine; Female; Haloperidol; Macaca mulatta; Male; Memory; Naloxone; Noise; Pattern Recognition, Visual; Prefrontal Cortex; Receptors, Dopamine; Stress, Psychological | 1998 |
Acutely administered clozapine does not modify naloxone-induced withdrawal jumping in morphine-dependent mice.
Topics: Analgesics; Animals; Antipsychotic Agents; Clonidine; Clozapine; Haloperidol; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome | 1999 |
Neurotransmitter-mediated open-field behavioral action of CGRP.
Topics: Animals; Atropine; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Exploratory Behavior; Grooming; Haloperidol; Injections, Intraventricular; Locomotion; Male; Methysergide; Motor Activity; Naloxone; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar | 1999 |
Dopamine-opiate interaction in the regulation of neostriatal and pallidal neuronal activity as assessed by opioid precursor peptides and glutamate decarboxylase messenger RNA expression.
Topics: Animals; Dopamine; Dopamine Antagonists; Dynorphins; Enkephalins; Globus Pallidus; Glutamate Decarboxylase; Haloperidol; Male; Naloxone; Narcotic Antagonists; Neostriatum; Neurons; Opioid Peptides; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, mu; RNA, Messenger | 1999 |
Effects of SCH 23390, raclopride, and haloperidol on morphine withdrawal-induced aggression in male mice.
Topics: Aggression; Animals; Antipsychotic Agents; Benzazepines; Dopamine Antagonists; Haloperidol; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Raclopride; Salicylamides; Social Behavior; Substance Withdrawal Syndrome | 1999 |
Dopaminergic and opioidergic mediations of tricyclic antidepressants in the learned helplessness paradigm.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Desipramine; Dibenzocycloheptenes; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Interactions; Escape Reaction; Haloperidol; Helplessness, Learned; Imipramine; Male; Motor Activity; Naloxone; Narcotic Antagonists; Opioid Peptides; Rats; Rats, Wistar | 1999 |
Combined effects of diethylpropion and alcohol on locomotor activity of mice: participation of the dopaminergic and opioid systems.
Topics: Animals; Appetite Depressants; Central Nervous System Depressants; Diethylpropion; Dopamine Antagonists; Drug Interactions; Ethanol; Haloperidol; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists | 1999 |
Involvement of mu-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: studies using mu-opioid receptor gene knockout mice.
Topics: Analgesics, Opioid; Animals; Apomorphine; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Haloperidol; Mice; Mice, Knockout; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu | 2000 |
The action of orexin A on passive avoidance learning. Involvement of transmitters.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Avoidance Learning; Bicuculline; Carrier Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neuropeptides; Neurotransmitter Agents; Nitric Oxide Synthase; Orexins; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar | 2002 |
Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Enkephalin, Methionine; Exploratory Behavior; Haloperidol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neostriatum; Organ Culture Techniques; Peptide Fragments; Pituitary-Adrenal System | 2003 |
[Method for determining dopamine and morphine binding sites in lymphocytes from human peripheral blood].
Topics: Alcohol Drinking; Binding Sites; Dopamine; Dopamine Antagonists; Ethanol; Haloperidol; Histocytochemistry; Humans; In Vitro Techniques; Ligands; Lymphocytes; Morphine; Naloxone; Receptors, Opioid, mu; Serum Albumin | 2003 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
Effects of pituitary adenylate cyclase polypeptide (PACAP) on extinction of active avoidance learning in rats: involvement of neurotransmitters.
Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Bicuculline; Dopamine Antagonists; Enzyme Inhibitors; GABA Antagonists; Haloperidol; Male; Naloxone; Narcotic Antagonists; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nitroarginine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar | 2005 |
Effect of glutamate receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
Topics: Animals; Avoidance Learning; Conditioning, Psychological; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley | 2005 |
Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice.
Topics: Analgesics; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Formaldehyde; Haloperidol; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Time Factors | 2005 |
Reversal of morphine with naloxone precipitates haloperidol-induced extrapyramidal side effects.
Topics: Adolescent; Analgesics, Opioid; Antipsychotic Agents; Basal Ganglia Diseases; Drug Interactions; Female; Haloperidol; Humans; Injections, Spinal; Morphine; Naloxone; Narcotic Antagonists; Neoplasms | 2006 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Activation of maternal behavior of albino rats after combined treatment with dopamine and opioid receptor antagonists in low doses.
Topics: Analysis of Variance; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Haloperidol; Maternal Behavior; Motor Activity; Naloxone; Narcotic Antagonists; Rats | 2006 |
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Dopamine Antagonists; Ethanol; Flumazenil; GABA Modulators; Haloperidol; Indoles; Naloxone; Narcotic Antagonists; Olanzapine; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin Receptor Agonists; Stress, Physiological; Substance Withdrawal Syndrome | 2007 |
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.
Topics: Analysis of Variance; Animals; Brain; Capsaicin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Hyperalgesia; Mice; Morpholines; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pentazocine; Physical Stimulation; Protein Binding; Radioligand Assay; Reaction Time; Receptors, sigma; Rotarod Performance Test; Sigma-1 Receptor; Tritium | 2009 |
Gastric pentadecapeptide BPC 157 counteracts morphine-induced analgesia in mice.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Haloperidol; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Peptide Fragments; Proteins; Random Allocation; Time Factors | 2009 |
Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Pain; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Subthalamic Nucleus; Subthalamus | 2012 |
Involvement of transmitters in the anxiolytic action of urocortin 3 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Atropine; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Maze Learning; Methysergide; Mice; Naloxone; Neurotransmitter Agents; Propranolol; Time Factors; Urocortins | 2013 |
Transmitter mediation of the anxiolytic action of apelin-13 in male mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Atropine; Bicuculline; Dopamine Antagonists; GABA-A Receptor Antagonists; Haloperidol; Intercellular Signaling Peptides and Proteins; Male; Maze Learning; Methysergide; Mice; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Phenoxybenzamine; Propranolol; Receptors, Neurotransmitter; Serotonin Antagonists | 2014 |
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats.
Topics: Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Anxiety; Arginine; Atropine; Bicuculline; Dopamine Antagonists; Exploratory Behavior; Haloperidol; Male; Maze Learning; Methysergide; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nitroso Compounds; Peptide Fragments; Phenoxybenzamine; Pituitary Adenylate Cyclase-Activating Polypeptide; Propranolol; Rats; Rats, Wistar; Receptors, GABA; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Analgesics; Animals; Behavior, Animal; Cedrus; Disease Models, Animal; Dopamine Antagonists; Fenclonine; Foot; Haloperidol; Hyperalgesia; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oils, Volatile; Pain, Postoperative; Phytotherapy; Serotonin Antagonists; Yohimbine | 2015 |
A new animal model of placebo analgesia: involvement of the dopaminergic system in reward learning.
Topics: Analgesia; Animals; Dopamine Antagonists; Gyrus Cinguli; Haloperidol; Immunohistochemistry; Male; Models, Animal; Naloxone; Narcotic Antagonists; Pain; Pain Threshold; Placebo Effect; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2015 |
Antiallodynic Activity of Ceftriaxone and Clavulanic Acid in Acute Administration is Associated with Serum TNF-α Modulation and Activation of Dopaminergic and Opioidergic Systems.
Topics: Animals; Ceftriaxone; Clavulanic Acid; Cold Temperature; Dopamine Antagonists; Gene Expression Regulation; Haloperidol; Hyperalgesia; Injections, Intraperitoneal; Male; Naloxone; Narcotic Antagonists; Rats; Touch; Tumor Necrosis Factor-alpha | 2017 |
Opioidergic and dopaminergic modulation of cost/benefit decision-making in Long Evans Rats.
Topics: Animals; Appetite; Decision Making; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Eating; Feeding and Eating Disorders; Feeding Behavior; Haloperidol; Male; Motivation; Naloxone; Narcotic Antagonists; Rats, Long-Evans; Receptors, Dopamine; Receptors, Opioid; Reinforcement, Psychology; Taste Perception | 2017 |