haloperidol and maprotiline

haloperidol has been researched along with maprotiline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.69)18.7374
1990's3 (10.34)18.2507
2000's12 (41.38)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Schmidt, WJ1
Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S1
Höffken, K; Kloke, M; Olbrich, H; Schmidt, CG1
Carboni, E; Di Chiara, G; Frau, R; Tanda, GL1
La Cascia, C; Mascarella, A; Migneco, G; Navetta, A; Tripi, S1
Gelbtuch, MH; Harris, JP; Phillipson, OT1
Calvert, JE; Gelbtuch, MH; Harris, JP; Phillipson, OT1
Binz, U; Herberger, B; Kissling, W; Möller, HJ; Spahn, H; Wendt, G1
König, F; Straub, R; Wolfersdorf, M1
Kanba, S; Miyaoka, H; Nakaki, T; Shintani, F; Suzuki, E1
Ginovart, N; Houle, S; Hussey, D; Meyer, JH; Wilson, AA1

Reviews

1 review(s) available for haloperidol and maprotiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for haloperidol and maprotiline

ArticleYear
Effects of haloperidol and nomifensine on the visual aftereffects of tilt and movement.
    Psychopharmacology, 1986, Volume: 89, Issue:2

    Topics: Adult; Afterimage; Arousal; Eye Movements; Female; Haloperidol; Humans; Male; Maprotiline; Motion; Movement; Nomifensine; Posture; Reaction Time; Sleep Stages; Visual Acuity

1986
Controlled trial on the possible advantages of a combined therapy with maprotiline and haloperidol in endogenous depression.
    Pharmacopsychiatry, 1986, Volume: 19, Issue:5

    Topics: Adult; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Maprotiline; Middle Aged

1986

Other Studies

26 other study(ies) available for haloperidol and maprotiline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of d-amphetamine, maprotiline, L-dopa, and haloperidol on the components of the predatory behavior of the ferret, Putorius furo L.
    Psychopharmacology, 1979, Volume: 64, Issue:3

    Topics: Animals; Anthracenes; Appetitive Behavior; Behavior, Animal; Carnivora; Dextroamphetamine; Ferrets; Haloperidol; Levodopa; Male; Maprotiline; Predatory Behavior; Time Factors

1979
[Behavior pharmacology of maprotiline, a new antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Catalepsy; Escape Reaction; Eyelids; Haloperidol; Humans; Imipramine; Levodopa; Maprotiline; Methamphetamine; Mice; Motor Activity; Oxotremorine; Physostigmine; Rats; Reserpine; Sleep; Tetrabenazine

1975
Anti-depressants and anti-convulsants for the treatment of neuropathic pain syndromes in cancer patients.
    Onkologie, 1991, Volume: 14, Issue:1

    Topics: Analgesics; Anticonvulsants; Antidepressive Agents; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Maprotiline; Neoplasm Metastasis; Neoplasms; Neuralgia; Pain Measurement

1991
Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: Animals; Caudate Nucleus; Desipramine; Dopamine; Drug Synergism; Extracellular Space; Frontal Lobe; Haloperidol; Hydroxydopamines; Male; Maprotiline; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains

1990
[Cytolytic episodes during cirrhosis].
    La Clinica terapeutica, 1986, Jul-31, Volume: 118, Issue:2

    Topics: Antipyrine; Anxiety Disorders; Barbiturates; Caffeine; Cholestasis; Drug Therapy, Combination; Female; Haloperidol; Humans; Liver Cirrhosis; Maprotiline; Middle Aged; Recurrence; Temazepam; Time Factors

1986
Modification of visual orientation illusions by drugs which influence dopamine and GABA neurones: differential effects on simultaneous and successive illusions.
    Psychopharmacology, 1986, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Dopamine; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Illusions; Lorazepam; Male; Maprotiline; Neurons; Nomifensine; Optical Illusions; Orientation

1986
Pharmacotherapy of delusional depression: experience with combinations of antidepressants with the neuroleptics zotepine and haloperidol.
    Neuropsychobiology, 1994, Volume: 29, Issue:4

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Delusions; Depressive Disorder; Dibenzothiepins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales

1994
Antipsychotic, antidepressant, anxiolytic, and anticonvulsant drugs induce type II nitric oxide synthase mRNA in rat brain.
    Neuroscience letters, 2002, Nov-29, Volume: 333, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Brain; Carbamazepine; Chlorpromazine; Diazepam; Fluvoxamine; Gene Expression; Haloperidol; Isoxazoles; Lithium; Male; Maprotiline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Zonisamide

2002
[11C]-DASB, a tool for in vivo measurement of SSRI-induced occupancy of the serotonin transporter: PET characterization and evaluation in cats.
    Synapse (New York, N.Y.), 2003, Volume: 47, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzylamines; Brain; Carrier Proteins; Cats; Citalopram; Dopamine Antagonists; Fluoxetine; Haloperidol; Maprotiline; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Tranylcypromine

2003