haloperidol and l 741626

haloperidol has been researched along with l 741626 in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Baker, R; Broughton, HB; Curtis, NR; Emms, F; Freedman, SB; Kulagowski, JJ; Leeson, PD; Marwood, R; Mawer, IM; Patel, S; Ragan, CI; Ridgill, MP1
Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ablordeppey, SY; Altundas, R; Nkansah, NT; Roth, BL; Setola, V; Sikazwe, DM; Zhu, XY1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Babic, S; Calvin, W; Cui, J; Luedtke, RR; Mach, RH; Taylor, M; Vangveravong, S; Xu, J1
Barnaeva, E; Bryant-Genevier, M; Conroy, JL; Doyle, T; Dulcey, AE; Ferrer, M; Free, RB; Hu, X; Marugan, JJ; Miller, B; Sibley, DR; Southall, N; Taylor, MK; Titus, S; Xiao, J; Zheng, W1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Itkin, M; Kabir, M; Mathé, EA; Nguyễn, ÐT; Padilha, EC; Shah, P; Shinn, P; Siramshetty, V; Wang, AQ; Williams, J; Xu, X; Yu, KR; Zhao, T1
Fushiki, T; Imaizumi, M; Takeda, M1
Bergeron, J; Courtney, C; McConkey, M; Melch, M; Shrikhande, A; Smith, D; Wong, SK1
Hattori, K; Isosaka, T; Iyo, M; Kohsaka, S; Maekawa, M; Sato, T; Uchino, S; Yagi, T; Yuasa, S1
Arai, Y; Kikuchi, T; Mitazaki, S; Nakagawasai, O; Nakaya, K; Niijima, F; Onogi, H; Sato, A; Tadano, T; Tan-No, K1
Davoodi, N; Langlois, X; te Riele, P1

Reviews

1 review(s) available for haloperidol and l 741626

ArticleYear
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
    Bioorganic & medicinal chemistry, 2022, 02-15, Volume: 56

    Topics: Administration, Oral; Animals; Betamethasone; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Madin Darby Canine Kidney Cells; Mice; Molecular Structure; Neural Networks, Computer; Ranitidine; Rats; Structure-Activity Relationship; Verapamil

2022

Other Studies

15 other study(ies) available for haloperidol and l 741626

ArticleYear
3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.
    Journal of medicinal chemistry, 1996, May-10, Volume: 39, Issue:10

    Topics: Animals; Cell Line; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Pyridines; Pyrroles; Receptors, Dopamine D4

1996
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Antipsychotic Agents; Binding Sites; Butyrophenones; Haloperidol; Humans; Indoles; Kinetics; Ligands; Receptors, Dopamine D2; Structure-Activity Relationship

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626.
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Adenylyl Cyclases; Benzofurans; Cell Line; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Indoles; Protein Binding; Receptors, Dopamine D2; Thiophenes

2010
Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.
    Journal of medicinal chemistry, 2014, Apr-24, Volume: 57, Issue:8

    Topics: Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Discovery; HEK293 Cells; High-Throughput Screening Assays; Humans; Structure-Activity Relationship

2014
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Effects of oil intake in the conditioned place preference test in mice.
    Brain research, 2000, Jul-07, Volume: 870, Issue:1-2

    Topics: Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Conditioning, Psychological; Corn Oil; Dopamine Antagonists; Eating; Haloperidol; Indoles; Male; Mice; Piperidines; Receptors, Dopamine D1; Reward; Space Perception; Sulpiride

2000
Fully automated radioligand binding filtration assay for membrane-bound receptors.
    BioTechniques, 2002, Volume: 33, Issue:4

    Topics: Animals; Automation; Binding, Competitive; CHO Cells; Cricetinae; Filtration; Haloperidol; Indoles; Piperidines; Radioligand Assay; Receptors, Dopamine; Reproducibility of Results; Time Factors

2002
Fyn is required for haloperidol-induced catalepsy in mice.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Blotting, Western; Calcium; Catalepsy; Cells, Cultured; Dopamine; Genotype; Haloperidol; Immunoblotting; Immunohistochemistry; Immunoprecipitation; In Situ Hybridization; Indoles; Mice; Neurons; Phosphorylation; Piperidines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors; Tyrosine

2006
p-Hydroxyamphetamine causes prepulse inhibition disruptions in mice: contribution of dopamine neurotransmission.
    Behavioural brain research, 2010, Dec-25, Volume: 214, Issue:2

    Topics: Animals; Benzazepines; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Oxidopamine; p-Hydroxyamphetamine; Piperazines; Piperidines; Pyridines; Pyrroles; Reflex, Startle; Salicylamides; Sensory Gating; Sympathomimetics; Synaptic Transmission

2010
Examining dopamine D3 receptor occupancy by antipsychotic drugs via [3H]7-OH-DPAT ex vivo autoradiography and its cross-validation via c-fos immunohistochemistry in the rat brain.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dopamine Antagonists; Haloperidol; Indoles; Islands of Calleja; Male; Nitriles; Olanzapine; Piperidines; Proto-Oncogene Proteins c-fos; Radiography; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines; Tetrahydronaphthalenes

2014