haloperidol has been researched along with ketamine in 115 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (17.39) | 18.7374 |
| 1990's | 23 (20.00) | 18.2507 |
| 2000's | 25 (21.74) | 29.6817 |
| 2010's | 31 (26.96) | 24.3611 |
| 2020's | 16 (13.91) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Friedman, SJ; Skehan, P | 1 |
| Pierson, C; Quadri, SK; Spies, HG | 1 |
| Joshi, RS; Marco, LA | 1 |
| Berger, P; Butman, M; Graham, SH; Koistinaho, J; Longo, FM; Noble, L; Sagar, SM; Sharp, FR; Wang, S | 1 |
| Sagrillo, CA; Voogt, JL | 1 |
| Brent, PJ | 1 |
| Irifune, M; Nomoto, M; Shimizu, T | 1 |
| Di Scala, G; Kempf, E; Lannes, B; Micheletti, G; Warter, JM | 1 |
| Lipton, P; Lobner, D | 1 |
| Calder, LD; Chaudhry, IA; Karler, R; Turkanis, SA | 1 |
| Choudhary, AK; Gurtu, S; Mukherjee, D; Seth, S; Sinha, JN | 1 |
| Kovalev, GV; Kuleshova, IP; Sazhin, VA | 1 |
| Allikmets, LKh; Kharro, IaE; Lang, AE; Vasar, EE | 1 |
| Aldes, LD; Brigham, TE; Chronister, RB; Marco, LA; Pendleton, R; Reed, TF | 1 |
| Ahlemeyer, B; Krieglstein, J | 1 |
| Colpaert, FC; Kamenka, JM; Koek, W; Woods, JH | 1 |
| Fletcher, JE; Lizzo, FH; Rosenberg, H | 1 |
| Aldes, LD; Brown, CB; Chronister, RB; Marco, LA; Reed, TF; White, LE | 1 |
| Gibbens, H; Headley, PM; Magnago, TS; Parsons, CG | 1 |
| Johnson, KM; Snell, LD | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Allikmets, LKh; Soosaar, AKh; Vasar, EE | 1 |
| Aldes, LD; Chronister, RB; Marco, LA; Reed, TF | 1 |
| Morato, GS; Takahashi, RN | 1 |
| Benediktov, II; Blinov, PS | 1 |
| Davis, H | 1 |
| Gannon, RL; Johnson, KM; Mueller, ZL; Silverman, PB; Snell, LD | 1 |
| Cetina, J | 1 |
| Freedman, R; Hoffer, B; Marwaha, J; Palmer, M | 1 |
| Beani, L; Bianchi, C; Casamenti, F; Pepeu, G | 1 |
| Kulkarni, SK; Verma, A | 1 |
| Lannes, B; Micheletti, G; Warter, JM; Zwiller, J | 1 |
| Chiou, GC; Li, BH; Rohde, BH | 1 |
| Berger, P; Butman, M; Graham, SH; Koistinaho, J; Longo, FM; Sagar, SM; Sharp, FR; Wang, S | 1 |
| Koffel, B; Lahti, AC; LaPorte, D; Tamminga, CA | 1 |
| Chang, J; Nakki, R; Nickolenko, J; Sagar, SM; Sharp, FR | 1 |
| Gupta, MC; Singh, J | 1 |
| Conley, RR; Tamminga, CA | 1 |
| Duncan, GE; Leipzig, JN; Lieberman, JA; Mailman, RB | 1 |
| Bakshi, V; Geyer, MA; Swerdlow, NR; Taaid, N; Waikar, M | 1 |
| Abi-Dargham, A; Abi-Saab, D; Bennett, A; Bowers, MB; Cassello, K; Charney, DS; D'Souza, DC; Heninger, GR; Karper, LP; Krystal, JH; Vegso, S | 1 |
| Carpenter, WT | 1 |
| Hernández-Carrasquilla, M; Olmos-Carmona, ML | 1 |
| Condon, M; Giannini, AJ; Underwood, NA | 1 |
| Kumar, A; Singh, KI; Sobti, VK | 1 |
| Holcomb, HH; Lahti, AC; Medoff, DR; Tamminga, CA | 1 |
| Kambara, T; Masuzawa, M; Miyamoto, E; Nakao, S; Shingu, K | 1 |
| Breese, GR; Moy, SS | 1 |
| Franks, NP; Ma, D; Maze, M; Wilhelm, S | 1 |
| Gispen-de Wied, CC; Kahn, RS; Oranje, B; Verbaten, MN | 1 |
| Duncan, GE; Lieberman, JA; Miyamoto, S | 1 |
| Arima, K; Barr, AM; Dwork, AJ; Falkai, P; Honer, WG; Nakamura, M; Phillips, AG; Sawada, K; Young, CE | 1 |
| Guimarães, FS; Moreira, FA | 1 |
| Coimbra, NC; Cunha, AO; de Oliveira, L; Dos Santos, WF; Mortari, MR | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; López-Gil, X | 1 |
| Bosnyakova, D; Coenen, A; Gabova, A; Kuznetsova, G; Midzyanovskaya, I; Obukhov, Y; Salonin, D; Tuomisto, L; van Luijtelaar, G; van Rijn, C | 1 |
| Cromwell, HC; Woodward, DJ | 1 |
| Ehrlichman, RS; Hans, ML; Liang, Y; Lowman, AM; Maxwell, C; Metzger, K; Siegel, SJ | 1 |
| Cilia, J; Hatcher, P; Jones, DN; Reavill, C | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Akanmu, MA; Owolabi, AR; Ukponmwan, OE | 1 |
| Elsinga, PH; Kortekaas, R; Leenders, KL; Maguire, RP; van Waarde, A | 1 |
| Becker, A; Grecksch, G; Hiemke, C; Ladstaetter, E; Schmitt, U; Zernig, G | 1 |
| Contreras, D; Ehrlichman, RS; Finkel, LH; Gandal, MJ; Lazarewicz, MT; Maxwell, CR; Siegel, SJ; Turetsky, BI | 1 |
| Gispen-de Wied, CC; Kahn, RS; Kemner, C; Oranje, B; Verbaten, MN; Westenberg, HG | 1 |
| Chatterjee, M; Ganguly, S; Palit, G; Srivastava, M | 1 |
| Carvalho, AF; de Araújo, FY; de Moraes, ME; de Moraes, MO; de Oliveira, GV; de Sousa, FC; Gomes, PX; Macêdo, DS; Silva, MI; Soares, MA; Vasconcelos, SM; Viana, GS | 1 |
| Anderson, P; Jones, NC; O'Brien, TJ; Pinault, D; Reddy, M; Salzberg, MR | 1 |
| Adzu, B; Chindo, BA; Gamaniel, KS; Yahaya, TA | 1 |
| Conway, MW; Francois, J; Gilmour, G; Huxter, J; Ishiwari, K; Li, J; Lowry, JP; Schwarz, AJ; Tricklebank, M | 1 |
| Deng, CM; Gao, YY; Li, Y; Mu, YL; Ou, BC; So, JH; Tan, ZB; Tang, M; Wang, YQ; Zhang, LQ; Zhu, ZR | 1 |
| Amato, D; Carey, RJ; de Souza Silva, MA; Groos, D; Huston, JP; Lauber, AC; Müller, CP; Pum, ME | 1 |
| Hunt, MJ; Kasicki, S; Olszewski, M; Piasecka, J; Whittington, MA | 1 |
| Antonio, CB; Barreiro, EJ; Betti, AH; Fraga, CA; Herzfeldt, V; Rates, SM | 1 |
| Newland, MC; Shen, AN | 1 |
| Eder, M; Hladky, F; Holsboer, F; Schmidt, MV; Stepan, J; Uribe, A | 1 |
| Hudson, MR; Jones, NC; O'Brien, TJ; Rind, G | 1 |
| Bache-Wiig, P; Cole, JB; Engebretsen, KM; Fryza, BJ; Ho, JD; Kornas, RL; Moore, JC; Nystrom, PC; O'Brien-Lambert, A; Orozco, BS; Steinberg, LW; Stellpflug, SJ | 1 |
| Avvisati, L; Buonaguro, EF; Chiodini, P; de Bartolomeis, A; Iasevoli, F; Latte, G; Marmo, F; Rossi, R; Tomasetti, C | 1 |
| Benowitz, NL; Horng, H; Smollin, CG; Vo, KT | 1 |
| Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K | 1 |
| Onaolapo, AY; Onaolapo, OJ; Paul, TB | 1 |
| Ademakinwa, OQ; Olalekan, TO; Onaolapo, AY; Onaolapo, OJ | 1 |
| Blum, A; Hollinger, A; Riegger, H; Seifert, B; Siegemund, M; Toft, K; Zehnder, T | 1 |
| Aderibigbe, AO; Ajayi, AM; Ben-Azu, B; Eneni, AO; Iwalewa, EO; Umukoro, S | 1 |
| Herrera-Ruiz, M; Jiménez-Ferrer, E; Román-Ramos, R; Santillán-Urquiza, MA; Tortoriello, J; Zamilpa, A | 1 |
| Andolfatto, G; Barbic, D; Barbic, SP; Grunau, B; Honer, WG; MacEwan, W; Scheuermeyer, FX; Wong, H | 1 |
| Abdolrazaghnejad, A; Akhlaghi, AA; Akhlaghi, N; Payandemehr, P; Yaseri, M | 1 |
| Lee, P; Murray, H | 1 |
| Agartz, I; Bohman, H; Curbo, S; Lundberg, M; Mansouri, S; Ögren, SO; Patrone, C | 1 |
| Calvo, R; Cannis, M; Figuerado, Y; Lee, J; Lin, J; Montgomery, A; Norton, VC; Sikand, H | 1 |
| Barletta, JF; Erstad, BL | 1 |
| Brügger, J; Gysi, B; Hollinger, A; Huber, J; Rentsch, K; Riegger, H; Rüst, CA; Schmid, HR; Siegemund, M; Steiner, L; Surbeck, M; Toft, K; Tran, F | 1 |
| Hunt, MJ; Jurkiewicz, G; Średniawa, W; Whittington, MA; Wójcik, DK; Wróbel, J; Żygierewicz, J | 1 |
| Aguiar-Geraldo, JM; Araujo, SL; Cararo, JH; Mastella, GA; Menegas, S; Possamai-Della, T; Quevedo, J; Valvassori, SS; Zugno, AI | 1 |
| Bosc, M; Kepecs, A; Ott, T; Schmack, K; Sturgill, JF | 1 |
| Bakker, IM; Kamphuis, J; Schoevers, RA; Smith-Apeldoorn, SY; Touw, DJ; Veraart, JKE; Visser, BAE | 1 |
| Andolfatto, G; Barbic, D; Barbic, SP; Grunau, B; Honer, WG; Macewan, B; Qian, H; Scheuermeyer, FX; Wong, H | 1 |
| Li, J; Liu, J; Yu, D | 1 |
| Austin, E; Kent, J; Nolan, B | 1 |
| Baratloo, A; Moradi, MM; Payandemehr, P; Safaie, A | 1 |
| Li, H; Li, P; Li, S; Wang, R | 1 |
| Adamek, P; Holubova, K; Horacek, J; Horka, P; Hubeny, J; Langova, V; Novak, T; Vales, K | 1 |
| da Rosa, RT; Dal-Pont, GC; Daminelli, T; Fries, GR; Mastella, GA; Quevedo, J; Valvassori, SS; Varela, RB; Zugno, AI | 1 |
6 review(s) available for haloperidol and ketamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The application of neuroimaging techniques to drug development.
Topics: Antipsychotic Agents; Brain; Brain Chemistry; Carbon Radioisotopes; Cerebrovascular Circulation; Deoxyglucose; Diagnostic Imaging; Drug Industry; Drugs, Investigational; Fluorodeoxyglucose F18; Haloperidol; Humans; Ketamine; Magnetic Resonance Imaging; Mental Disorders; Neuropharmacology; Receptors, Dopamine; Spiperone; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 1997 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
Drug dosing in the critically ill obese patient-a focus on sedation, analgesia, and delirium.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Benzodiazepines; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Etomidate; Haloperidol; Humans; Ketamine; Obesity; Pain Management; Quetiapine Fumarate | 2020 |
Pharmacodynamic Interactions Between Ketamine and Psychiatric Medications Used in the Treatment of Depression: A Systematic Review.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depression; Drug Interactions; Female; Haloperidol; Humans; Ketamine; Lithium; Male; Olanzapine; Psychotropic Drugs; Risperidone; Schizophrenia; Treatment Outcome | 2021 |
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; Nefopam; Pain, Postoperative; Pregabalin; Tolterodine Tartrate; Tramadol; Urinary Bladder; Urinary Catheters | 2022 |
13 trial(s) available for haloperidol and ketamine
| Article | Year |
|---|---|
Subanesthetic doses of ketamine stimulate psychosis in schizophrenia.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glutamic Acid; Haloperidol; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Psychoses, Substance-Induced; Schizophrenia; Time Factors | 1995 |
Interactive effects of subanesthetic ketamine and haloperidol in healthy humans.
Topics: Adult; Anesthetics, Dissociative; Antipsychotic Agents; Cognition; Double-Blind Method; Drug Interactions; Female; Haloperidol; Humans; Hydrocortisone; Ketamine; Male; Prolactin; Receptors, N-Methyl-D-Aspartate; Sleep Stages | 1999 |
The schizophrenia ketamine challenge study debate.
Topics: Anesthetics, Dissociative; Anxiety; Bioethics; Brief Psychiatric Rating Scale; Consumer Product Safety; Haloperidol; Humans; Ketamine; Patient Advocacy; Psychoses, Substance-Induced; Research; Schizophrenia | 1999 |
Acute ketamine intoxication treated by haloperidol: a preliminary study.
Topics: Adult; Anesthetics, Dissociative; Antipsychotic Agents; Double-Blind Method; Haloperidol; Humans; Ketamine; Male; Psychoses, Substance-Induced | 2000 |
Modulating sensory gating in healthy volunteers: the effects of ketamine and haloperidol.
Topics: Adult; Antipsychotic Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electroencephalography; Electrooculography; Evoked Potentials; Excitatory Amino Acid Antagonists; Haloperidol; Heart Rate; Homovanillic Acid; Humans; Hydrocortisone; Ketamine; Male; Neurons, Afferent; Neurotransmitter Agents; Prolactin; Reflex, Startle; Schizophrenia | 2002 |
Haloperidol counteracts the ketamine-induced disruption of processing negativity, but not that of the P300 amplitude.
Topics: Acoustic Stimulation; Adult; Affect; Attention; Behavior; Blood Pressure; Contingent Negative Variation; Dopamine Antagonists; Double-Blind Method; Drug Interactions; Electroencephalography; Electrooculography; Event-Related Potentials, P300; Excitatory Amino Acid Antagonists; Haloperidol; Heart Rate; Homovanillic Acid; Humans; Ketamine; Male; Multivariate Analysis; Neuropsychological Tests; Prolactin; Psychiatric Status Rating Scales; Reaction Time; Time Factors; Young Adult | 2009 |
Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial (PRIDe): a phase IV multicenter, randomized, placebo-controlled, double-blind clinical trial of ketamine versus haloperidol for prevention of postoperative delirium.
Topics: Anesthetics, Dissociative; Antipsychotic Agents; Clinical Trials, Phase IV as Topic; Delirium; Double-Blind Method; Haloperidol; Humans; Incidence; Ketamine; Multicenter Studies as Topic; Postoperative Complications; Randomized Controlled Trials as Topic; Risk Factors; Switzerland; Time Factors; Treatment Outcome | 2018 |
Rapid agitation control with ketamine in the emergency department (RACKED): a randomized controlled trial protocol.
Topics: Adult; Anesthetics, Dissociative; British Columbia; Emergency Service, Hospital; Female; Haloperidol; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Ketamine; Male; Midazolam; Middle Aged; Prospective Studies; Psychomotor Agitation; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Violence; Young Adult | 2018 |
Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.
Topics: Administration, Intravenous; Adult; Anxiety; Conscious Sedation; Double-Blind Method; Emergency Service, Hospital; Female; Haloperidol; Humans; Ketamine; Male; Midazolam; Middle Aged; Premedication; Treatment Outcome; Young Adult | 2019 |
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Anti-Anxiety Agents; Antipsychotic Agents; Emergency Service, Hospital; Female; Haloperidol; Humans; Ketamine; Lorazepam; Male; Middle Aged; Pilot Projects; Prospective Studies; Psychomotor Agitation; United States | 2021 |
Ketamine vs. haloperidol for prevention of cognitive dysfunction and postoperative delirium: A phase IV multicentre randomised placebo-controlled double-blind clinical trial.
Topics: Adult; Cognitive Dysfunction; Delirium; Double-Blind Method; Haloperidol; Humans; Ketamine | 2021 |
Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial.
Topics: Adult; Anesthetics, Dissociative; Canada; Female; Haloperidol; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Ketamine; Male; Midazolam; Middle Aged; Psychomotor Agitation | 2021 |
Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Double-Blind Method; Emergency Service, Hospital; Fentanyl; Haloperidol; Humans; Ketamine | 2022 |
96 other study(ies) available for haloperidol and ketamine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
The inhibition of sterol synthesis by anesthetics.
Topics: Acetates; Anesthetics, Local; Animals; Cell Line; Chlorpromazine; Diphenylacetic Acids; Glioma; Haloperidol; Ketamine; Lidocaine; Lipids; Pentobarbital; Rats; Sterols; Tetracaine | 1979 |
Effects of centrally acting drugs on serum prolactin levels in rhesus monkeys.
Topics: Anesthetics; Animals; Estradiol; Female; Haloperidol; Halothane; Haplorhini; Immobilization; Ketamine; Lidocaine; Macaca mulatta; Pentobarbital; Phenoxybenzamine; Phentolamine; Prolactin; Propranolol; Sympatholytics | 1978 |
A ketamine-induced rat model of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Haloperidol; Ketamine; Metoclopramide; Pharynx; Rats; Rats, Inbred Strains; Stereotyped Behavior; Tongue | 1992 |
Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine.
Topics: Amygdala; Animals; Base Sequence; Carbazoles; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Gene Expression; Haloperidol; Heat-Shock Proteins; Humans; Immunohistochemistry; Ketamine; Kinetics; Microscopy, Electron; Molecular Sequence Data; Neurons; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Phencyclidine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reference Values; Restriction Mapping; RNA, Messenger | 1992 |
Mechanisms for the stimulatory effects of opioidergic and serotonergic input signals on prolactin in pregnant rats.
Topics: alpha-Methyltyrosine; Animals; beta-Endorphin; Bromocriptine; Circadian Rhythm; Dopamine; Female; Haloperidol; Ketamine; Methyltyrosines; Naloxone; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1992 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Ketamine-induced hyperlocomotion associated with alteration of presynaptic components of dopamine neurons in the nucleus accumbens of mice.
Topics: Anesthesia; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Haloperidol; Ketamine; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurons; Nucleus Accumbens; Oxidopamine; Phenoxybenzamine; Propranolol; Synapses | 1991 |
Behavioural, pharmacological and biochemical effects of acute and chronic administration of ketamine in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catalepsy; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Ketamine; Male; Methyltyrosines; Motor Activity; Rats; Stereotyped Behavior | 1991 |
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate; Glutamates; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Ketamine; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1990 |
Amphetamine behavioral sensitization and the excitatory amino acids.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Cyproheptadine; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Ketamine; Male; Mice; Neuroeffector Junction; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1990 |
Opioid and non-opioid central cardiovascular effects of ketamine.
Topics: Animals; Blood Pressure; Cats; Cisterna Magna; Dose-Response Relationship, Drug; Haloperidol; Heart Rate; Hemodynamics; Injections; Ketamine; Naloxone; Phencyclidine; Pimozide; Receptors, Opioid; Receptors, sigma | 1990 |
[Pharmacological correction of ketamine-impaired spatial memory of rats].
Topics: Amnesia; Animals; Aspartic Acid; Haloperidol; Hippocampus; Ketamine; Memory, Short-Term; Physostigmine; Rats; Spatial Behavior | 1990 |
[Adaptive changes in sigma and phencyclidine receptors during the long-term use of haloperidol and raclopride in rats].
Topics: Adaptation, Physiological; Animals; Apomorphine; Behavior, Animal; Drug Interactions; Haloperidol; Ketamine; Phenazocine; Phencyclidine; Raclopride; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Salicylamides; Time Factors; Tritium | 1989 |
Ketamine-induced tongue protrusions in rats.
Topics: Animals; Deglutition; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Hypoglossal Nerve; Ketamine; Rats; Rats, Inbred Strains; Tongue | 1989 |
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Flunarizine; Haloperidol; Imipramine; Ketamine; Lidocaine; Nafronyl; Neurons; Pyrithioxin; Telencephalon | 1989 |
The phencyclidine (PCP) analog N-[1-(2-benzo(B)thiophenyl) cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801.
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dextroamphetamine; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Haloperidol; Ketamine; Methylphenidate; Mice; Phencyclidine; Rats; Seizures; Structure-Activity Relationship | 1989 |
Effects of droperidol, haloperidol and ketamine on halothane, succinylcholine and caffeine contractures: implications for malignant hyperthermia.
Topics: Animals; Caffeine; Contracture; Droperidol; Haloperidol; Halothane; Humans; Ketamine; Male; Malignant Hyperthermia; Rats; Rats, Inbred Strains; Succinylcholine | 1989 |
Cortical control of tongue contractility in the rat under ketamine anaesthesia.
Topics: Anesthesia; Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Haloperidol; Ketamine; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Tongue | 1989 |
At which 'sigma' site are the spinal actions of ketamine mediated?
Topics: Action Potentials; Animals; Binding, Competitive; Dibenzocycloheptenes; Dizocilpine Maleate; Haloperidol; Ketamine; Male; Motor Neurons; Nociceptors; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1988 |
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Involvement of opioid receptors in phencyclidine-induced enhancement of brain histamine turnover in mice.
Topics: Analgesics, Opioid; Animals; Brain; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Haloperidol; Histamine; Histidine Decarboxylase; Ketamine; Male; Methylhistidines; Mice; Naloxone; Pargyline; Phenazocine; Phencyclidine; Receptors, Opioid | 1987 |
[Antagonism of caerulein, a CCK-8 receptor agonist, to the behavioral effects of ketamine in mice and rats].
Topics: Amnesia; Animals; Ataxia; Behavior, Animal; Ceruletide; Haloperidol; Ketamine; Male; Mice; Motor Activity; Naloxone; Rats; Receptors, Cholecystokinin; Stereotyped Behavior | 1988 |
An electrographic characterization of ketamine-induced linguopharyngeal motor activity.
Topics: Animals; Deglutition; Dyskinesia, Drug-Induced; Electromyography; Female; Haloperidol; Ketamine; Rats; Rats, Inbred Strains; Tongue | 1988 |
Lack of the effect of ketamine on some dopaminergic behaviors in rats.
Topics: Animals; Apomorphine; Catalepsy; Haloperidol; Ketamine; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Yawning | 1986 |
[Methods of anesthesia in obstetric surgery].
Topics: Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Antipsychotic Agents; Atropine; Diphenhydramine; Droperidol; Female; Haloperidol; Halothane; Histamine H1 Antagonists; Humans; Ketamine; Lidocaine; Methoxyflurane; Parasympatholytics; Pregnancy; Pregnanediones; Promethazine; Trichloroethylene | 1974 |
Sedation of young children for electric response audiometry (ERA). Summary of a symposium.
Topics: Age Factors; Anesthesia, Inhalation; Audiometry; Barbiturates; Cerebral Cortex; Child; Child, Preschool; Chloral Hydrate; Chlorpromazine; Congresses as Topic; Diazepam; Diphenhydramine; Evoked Potentials; Haloperidol; Halothane; Humans; Hydroxybutyrates; Hydroxyzine; Hypnotics and Sedatives; Infant; Ketamine; Methaqualone; Nitrous Oxide; Promazine; Promethazine; Sleep | 1973 |
A comparison between classes of drugs having phencyclidine-like behavioral properties on dopamine efflux in vitro and dopamine metabolism in vivo.
Topics: Animals; Corpus Striatum; Dopamine; Haloperidol; In Vitro Techniques; Ketamine; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Phencyclidine; Structure-Activity Relationship | 1984 |
[Smooth induction of anaesthesia in children by means of oral or rectal ketamine-dehydrobenzperidol application (author's transl)].
Topics: Administration, Oral; Adolescent; Anesthesia; Atropine; Child; Child, Preschool; Droperidol; Female; Haloperidol; Humans; Infant; Ketamine; Male; Nitrous Oxide; Preanesthetic Medication; Rectum; Suppositories | 1982 |
Phencyclidine-induced depressions of cerebellar Purkinje neurons.
Topics: Animals; Electric Conductivity; Haloperidol; Ketamine; Male; Neurons; Phencyclidine; Purkinje Cells; Rats | 1980 |
Effect of haloperidol and pimozide on acetylcholine output from the cerebral cortex in rats and guinea pigs.
Topics: Acetylcholine; Acoustic Stimulation; Amphetamine; Anesthesia; Animals; Cerebral Cortex; Female; Guinea Pigs; Haloperidol; Ketamine; Male; Pimozide; Rats; Time Factors | 1980 |
N-Methyl-D-aspartate receptor participation in Parkinson's disease, a neurodegenerative disorder.
Topics: Animals; Antiparkinson Agents; Apomorphine; Benzazepines; Catalepsy; Dizocilpine Maleate; Haloperidol; Ketamine; Mice; Neuroprotective Agents; Parkinson Disease, Secondary; Perphenazine; Rats; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
Evidence for NMDA/D2 receptor-receptor interactions in the rat striatum.
Topics: Animals; Apomorphine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Globus Pallidus; Haloperidol; Ketamine; Male; Neural Pathways; Rats; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei | 1993 |
Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure.
Topics: Analgesics; Animals; Ciliary Body; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Haloperidol; Injections, Intravenous; Intraocular Pressure; Iris; Ketamine; Melatonin; Rabbits; Retina; Sclera; Veins; Xylazine | 1993 |
Heat shock proteins used to show that haloperidol prevents neuronal injury produced by ketamine, MK801, and phencyclidine.
Topics: Animals; Biomarkers; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gyrus Cinguli; Haloperidol; Heat-Shock Proteins; Ketamine; Neurons; Neurotoxins; Phencyclidine; Rats | 1993 |
Haloperidol prevents ketamine- and phencyclidine-induced HSP70 protein expression but not microglial activation.
Topics: Animals; Female; Gene Expression; Haloperidol; HSP70 Heat-Shock Proteins; Immunohistochemistry; Ketamine; Microglia; Phencyclidine; Rats; Rats, Sprague-Dawley | 1996 |
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine | 1997 |
Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation.
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Clozapine; Deoxyglucose; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Rats; Rats, Sprague-Dawley | 1998 |
Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Ketamine; Male; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 1998 |
Gas chromatographic-mass spectrometric analysis of veterinary tranquillizers in urine: evaluation of method performance.
Topics: Animals; Azaperone; Cattle; Gas Chromatography-Mass Spectrometry; Haloperidol; Ketamine; Phenothiazines; Piperazines; Pyridines; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Sheep; Swine; Tranquilizing Agents; Veterinary Medicine; Xylazine | 1999 |
Evaluation of haloperidol--ketamine mixture (1:1) anaesthesia in dogs.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Animals; Blood Cell Count; Blood Glucose; Dogs; Female; Haloperidol; Hemodynamics; Ketamine; Male; Reference Values; Reflex | 2001 |
Probing the human hippocampus using rCBF: contrasts in schizophrenia.
Topics: Acoustic Stimulation; Adult; Antipsychotic Agents; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Female; Haloperidol; Hippocampus; Humans; Ketamine; Magnetic Resonance Imaging; Male; Pitch Discrimination; Schizophrenia; Tomography, Emission-Computed | 2001 |
Ketamine-induced c-Fos expression in the mouse posterior cingulate and retrosplenial cortices is mediated not only via NMDA receptors but also via sigma receptors.
Topics: Animals; Anticonvulsants; Carbazoles; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Gyrus Cinguli; Haloperidol; Ketamine; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Presynaptic Terminals; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2002 |
Phencyclidine supersensitivity in rats with neonatal dopamine loss.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Benzazepines; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Haloperidol; Ketamine; Male; Motor Activity; Olanzapine; Oxidopamine; Phencyclidine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2002 |
Neuroprotective and neurotoxic properties of the 'inert' gas, xenon.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Biomarkers; Brain; Brain Injuries; Dizocilpine Maleate; Female; Gene Expression; Haloperidol; Ketamine; Models, Animal; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Xenon | 2002 |
Chronic administration of haloperidol and olanzapine attenuates ketamine-induced brain metabolic activation.
Topics: Analgesics; Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Brain; Clozapine; Deoxyglucose; Drug Interactions; Haloperidol; Ketamine; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley | 2003 |
Hippocampal complexin proteins and cognitive dysfunction in schizophrenia.
Topics: Adaptor Proteins, Vesicular Transport; Aged; Animals; Antipsychotic Agents; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Female; Haloperidol; Hippocampus; Humans; Immunohistochemistry; Ketamine; Male; Maze Learning; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Vesicular Glutamate Transport Protein 1; Vesicular Inhibitory Amino Acid Transport Proteins | 2005 |
Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Cannabidiol; Clozapine; Dextroamphetamine; Haloperidol; Injections, Intraperitoneal; Ketamine; Locomotion; Male; Mice; Sympathomimetics; Time Factors | 2005 |
Cataleptic activity of the denatured venom of the social wasp Agelaia vicina (Hymenoptera, Vespidae) in Rattus norvegicus (Rodentia, Muridae).
Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Freezing Reaction, Cataleptic; Haloperidol; Hymenoptera; Ketamine; Male; Mice; Microinjections; Motor Activity; Protein Denaturation; Psychomotor Performance; Rats; Rats, Wistar; Rotarod Performance Test; Theophylline; Time Factors; Vasodilator Agents; Wasp Venoms | 2006 |
Clozapine and olanzapine, but not haloperidol, suppress serotonin efflux in the medial prefrontal cortex elicited by phencyclidine and ketamine.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Microdialysis; Olanzapine; Phencyclidine; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Time Factors | 2006 |
Time-frequency analysis of spike-wave discharges using a modified wavelet transform.
Topics: Algorithms; Anesthetics, Dissociative; Animals; Anti-Allergic Agents; Anticonvulsants; Data Interpretation, Statistical; Dopamine Antagonists; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; Female; Fourier Analysis; Haloperidol; Ketamine; Male; Pyrilamine; Rats; Vigabatrin | 2006 |
Inhibitory gating of single unit activity in amygdala: effects of ketamine, haloperidol, or nicotine.
Topics: Acoustic Stimulation; Action Potentials; Amygdala; Animals; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Neural Inhibition; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2007 |
Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures.
Topics: Animals; Anti-Dyskinesia Agents; Delayed-Action Preparations; Drug Delivery Systems; Dyskinesia, Drug-Induced; Dyskinesias; Haloperidol; Ketamine; Male; Mice; Mice, Inbred C57BL; Micelles; Polyesters; Polyethylene Glycols | 2007 |
(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Ketamine; Lamotrigine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone; Schizophrenia; Sulfonamides; Thiophenes; Triazines | 2007 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Functional reactivity of the dopaminergic system following acute and chronic ketamine treatments.
Topics: Amphetamine; Animals; Apomorphine; Catalepsy; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Locomotion; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior | 2008 |
Despite irreversible binding, PET tracer [11C]-SA5845 is suitable for imaging of drug competition at sigma receptors-the cases of ketamine and haloperidol.
Topics: Algorithms; Anesthesia; Anesthetics, Dissociative; Animals; Antipsychotic Agents; Binding, Competitive; Brain; Excitatory Amino Acid Antagonists; Half-Life; Haloperidol; Ketamine; Ligands; Macaca mulatta; Male; Models, Statistical; Piperazines; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, sigma; Whole-Body Counting | 2008 |
Haloperidol and risperidone have specific effects on altered pain sensitivity in the ketamine model of schizophrenia.
Topics: Analgesics, Opioid; Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Morphine; Motor Activity; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Schizophrenic Psychology | 2009 |
N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia.
Topics: Acoustic Stimulation; Amphetamine; Animals; Antipsychotic Agents; Biological Clocks; Central Nervous System Stimulants; Disease Models, Animal; Drug Interactions; Electroencephalography; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Mice; Mice, Inbred C57BL; Reaction Time; Risperidone; Schizophrenia | 2009 |
Effect of 'chronic' versus 'acute' ketamine administration and its 'withdrawal' effect on behavioural alterations in mice: implications for experimental psychosis.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Ketamine; Male; Mice; Motor Activity; Psychotic Disorders; Random Allocation; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Swimming | 2011 |
Inhibition of ketamine-induced hyperlocomotion in mice by the essential oil of Alpinia zerumbet: possible involvement of an antioxidant effect.
Topics: Alpinia; Animals; Antioxidants; Antipsychotic Agents; Glutathione; Haloperidol; Hypnotics and Sedatives; Ketamine; Lipid Peroxidation; Locomotion; Male; Mice; Motor Activity; Nitrites; Oils, Volatile; Oxidative Stress; Plant Extracts; Plant Leaves; Schizophrenia; Sleep | 2011 |
Acute administration of typical and atypical antipsychotics reduces EEG γ power, but only the preclinical compound LY379268 reduces the ketamine-induced rise in γ power.
Topics: Amino Acids; Animals; Antipsychotic Agents; Brain Waves; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clozapine; Drug Administration Schedule; Electrodes, Implanted; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2012 |
Ketamine-enhanced immobility in forced swim test: a possible animal model for the negative symptoms of schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Disease Models, Animal; Female; Haloperidol; Immobility Response, Tonic; Ketamine; Male; Motor Activity; Rats; Rats, Wistar; Reproducibility of Results; Risperidone; Schizophrenia; Swimming | 2012 |
Dissociable effects of antipsychotics on ketamine-induced changes in regional oxygenation and inter-regional coherence of low frequency oxygen fluctuations in the rat.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Area Under Curve; Brain; Clozapine; Disease Models, Animal; Dissociative Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Oxygen; Rats; Tissue Distribution | 2014 |
Dopamine D2/D3 but not dopamine D1 receptors are involved in the rapid antidepressant-like effects of ketamine in the forced swim test.
Topics: Animals; Antidepressive Agents; Benzazepines; Benzothiazoles; Dizocilpine Maleate; Fluoxetine; Haloperidol; Ketamine; Male; Mice; Motor Activity; Pramipexole; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, N-Methyl-D-Aspartate; Swimming | 2015 |
Neuropharmacology of light-induced locomotor activation.
Topics: Animals; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Haloperidol; Indoles; Ketamine; Light; Male; Motor Activity; Naphthyridines; Phencyclidine; Photic Stimulation; Piperazines; Piperidines; Pyridines; Quinpirole; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serotonin Antagonists | 2015 |
Effects of NMDA receptor antagonists and antipsychotics on high frequency oscillations recorded in the nucleus accumbens of freely moving mice.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Mice; Nucleus Accumbens; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2015 |
LASSBio-579, a prototype antipsychotic drug, and clozapine are effective in novel object recognition task, a recognition memory model.
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Haloperidol; Ketamine; Male; Memory, Long-Term; Memory, Short-Term; Mice; Piperazines; Recognition, Psychology; Schizophrenia; Time Factors | 2016 |
Examination of clozapine and haloperidol in improving ketamine-induced deficits in an incremental repeated acquisition procedure in BALB/c mice.
Topics: Algorithms; Animals; Antipsychotic Agents; Clozapine; Cognition; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Haloperidol; Ketamine; Male; Mice; Mice, Inbred BALB C; Psychomotor Performance | 2016 |
High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit.
Topics: Animals; Antidepressive Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Chronic Disease; Diazepam; Disease Models, Animal; Dominance-Subordination; Fluoxetine; Haloperidol; Hippocampus; Ketamine; Lithium Compounds; Male; Mice, Inbred C57BL; Neural Pathways; Stress, Psychological; Tissue Culture Techniques; Voltage-Sensitive Dye Imaging | 2015 |
Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine.
Topics: Amino Acids; Animals; Antipsychotic Agents; Benzodiazepines; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Haloperidol; Ketamine; Male; Olanzapine; Prepulse Inhibition; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia | 2016 |
A prospective study of ketamine versus haloperidol for severe prehospital agitation.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dose-Response Relationship, Drug; Emergency Service, Hospital; Female; Haloperidol; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Ketamine; Male; Middle Aged; Prospective Studies; Psychomotor Agitation; Young Adult | 2016 |
Postsynaptic density protein transcripts are differentially modulated by minocycline alone or in add-on to haloperidol: Implications for treatment resistant schizophrenia.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Drug Resistance; Gene Expression; Haloperidol; Homer Scaffolding Proteins; Intracellular Signaling Peptides and Proteins; Ketamine; Male; Membrane Proteins; Minocycline; Nerve Tissue Proteins; Post-Synaptic Density; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2017 |
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Lorazepam; Male; Midazolam; Propofol; Quetiapine Fumarate; Respiration, Artificial; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
Comparative effects of sertraline, haloperidol or olanzapine treatments on ketamine-induced changes in mouse behaviours.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Anxiety; Behavior, Animal; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Grooming; Haloperidol; Interpersonal Relations; Ketamine; Male; Memory Disorders; Memory, Short-Term; Mice; Motor Activity; Olanzapine; Sertraline | 2017 |
Ketamine-induced behavioural and brain oxidative changes in mice: an assessment of possible beneficial effects of zinc as mono- or adjunct therapy.
Topics: Anesthetics, Dissociative; Animals; Antioxidants; Antipsychotic Agents; Benzodiazepines; Brain; Drug Therapy, Combination; Haloperidol; Interpersonal Relations; Ketamine; Male; Maze Learning; Mice; Olanzapine; Oxidative Stress; Schizophrenia; Treatment Outcome; Zinc | 2017 |
Involvement of GABAergic, BDNF and Nox-2 mechanisms in the prevention and reversal of ketamine-induced schizophrenia-like behavior by morin in mice.
Topics: Animals; Antioxidants; Behavioral Symptoms; Brain; Brain-Derived Neurotrophic Factor; Catalase; Disease Models, Animal; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Flavonoids; Haloperidol; Ketamine; Male; Memory, Short-Term; Mice; NADPH Oxidases; Risperidone; Schizophrenia; Stereotyped Behavior; Superoxide Dismutase; Swimming | 2018 |
Pharmacological interaction of Galphimia glauca extract and natural galphimines with Ketamine and Haloperidol on different behavioral tests.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Catalepsy; Dose-Response Relationship, Drug; Galphimia; Haloperidol; Herb-Drug Interactions; Ketamine; Male; Mice, Inbred ICR; Plant Extracts; Swimming; Triterpenes | 2018 |
Midazolam or haloperidol premedication reduced ketamine-induced recovery agitation and increased ED recovery time.
Topics: Adult; Double-Blind Method; Haloperidol; Humans; Ketamine; Midazolam; Premedication | 2019 |
Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy.
Topics: Adult Stem Cells; Animals; Apoptosis; Autophagy; Caspase 3; Cells, Cultured; Clozapine; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Lateral Ventricles; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2020 |
Nasal respiration is necessary for ketamine-dependent high frequency network oscillations and behavioral hyperactivity in rats.
Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Motor Activity; Nose; Prefrontal Cortex; Rats; Rats, Wistar; Respiration; Theta Rhythm; Ventral Striatum | 2020 |
Haloperidol elicits oxidative damage in the brain of rats submitted to the ketamine-induced model of schizophrenia.
Topics: Animals; Antipsychotic Agents; Brain; Haloperidol; Ketamine; Male; Oxidative Stress; Rats; Rats, Wistar; Schizophrenia; Superoxide Dismutase | 2021 |
Striatal dopamine mediates hallucination-like perception in mice.
Topics: Animals; Auditory Perception; Corpus Striatum; Dopamine; Female; Hallucinations; Haloperidol; Humans; Ketamine; Male; Mice, Inbred C57BL; Models, Neurological; Perception; Psychotic Disorders; Rats; Reward; Ventral Striatum | 2021 |
Comment on:"Ketamine vs haloperidol for prevention of cognitive dysfunction and postoperative delirium: A phase IV multicentre randomised placebo-controlled double-blind clinical trial".
Topics: Cognitive Dysfunction; Delirium; Double-Blind Method; Haloperidol; Humans; Ketamine | 2022 |
Does ketamine provide a shorter time to sedation when compared to haloperidol and midazolam in the agitated ED patient?
Topics: Anesthetics, Dissociative; Haloperidol; Humans; Hypnotics and Sedatives; Ketamine; Midazolam | 2022 |
Ketamine disrupts locomotion and electrolocation in a novel model of schizophrenia, Gnathonemus petersii fish.
Topics: Animals; Electric Fish; Haloperidol; Ketamine; Locomotion; Schizophrenia | 2023 |
Haloperidol alters neurotrophic factors and epigenetic parameters in an animal model of schizophrenia induced by ketamine.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epigenesis, Genetic; Glial Cell Line-Derived Neurotrophic Factor; Haloperidol; Humans; Ketamine; Nerve Growth Factor; Rats; Schizophrenia | 2023 |