haloperidol and idazoxan

haloperidol has been researched along with idazoxan in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's6 (23.08)18.2507
2000's8 (30.77)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Lookingland, KJ; Moore, KE; Tian, Y1
Boulat, O; Maitre, L; Waldmeier, P1
Hornykiewicz, O; Kobinger, W; Pichler, L; Pifl, C2
Cichini, G; Kraupp, O; Singer, EA; Valenta, B1
Bunney, BS; Chiodo, LA1
Engel, JA; Goldstein, M; Johannessen, K; Liljequist, S1
Clark, D; Eriksson, E; Svensson, K1
Kulkarni, SK; Sharma, A1
Novotney, S; Yamamoto, BK1
Chariot, J; Fu-Cheng, X; Rozé, C; Souli, A1
McAllister, KH; Rey, B1
Chariot, J; Presset, O; Rozé, C; Souli, A; Tsocas, A1
Devoto, P; Flore, G; Gessa, GL; Pani, L1
Garavaglia, C; Invernizzi, RW; Samanin, R1
Grottick, AJ; Herberg, LJ; Montgomery, AM1
Brotchie, JM; Fox, SH; Gomez-Ramirez, J; Johnston, TH; Lee, J1
Svensson, TH; Wadenberg, ML; Wiker, C1
Ball, GF; Castelino, CB; Cornil, CA1
Artigas, F; Bortolozzi, A; Masana, M1
Chau, DT; Dawson, R; Green, AI; Khokhar, JY1

Other Studies

26 other study(ies) available for haloperidol and idazoxan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Contribution of noradrenergic neurons to 3,4-dihydroxyphenylacetic acid concentrations in the regions of the rat brain containing incertohypothalamic dopaminergic neurons.
    Brain research, 1991, Jul-26, Volume: 555, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Apomorphine; Brain Chemistry; Dioxanes; Dopamine; Haloperidol; Hydrolysis; Hypothalamus; Idazoxan; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats

1991
3,4-Dihydroxyphenylacetic acid (DOPAC) as an index of noradrenaline turnover: effects of Hydergine and vincamine.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Cerebellum; Dihydroergotoxine; Dioxanes; Dopamine; Dopamine beta-Hydroxylase; Drug Interactions; Female; Haloperidol; Hippocampus; Idazoxan; Locus Coeruleus; Norepinephrine; Prazosin; Rats; Vincamine

1990
The dopamine autoreceptor agonist, B-HT 920, preferentially reduces brain dopamine release in vivo: biochemical indices of brain dopamine, noradrenaline and serotonin in ventriculocisternal perfusates in the cat.
    European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Animals; Azepines; Brain; Cats; Cerebral Ventricles; Cisterna Magna; Dioxanes; Dopamine; Dopamine Agents; Female; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Idazoxan; Male; Norepinephrine; Serotonin

1988
Effects of urapidil on catecholamine turnover and release in the central nervous system of the rat.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:3

    Topics: Animals; Blood Pressure; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Dioxanes; Dopamine; Electric Stimulation; Haloperidol; Idazoxan; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Inbred Strains

1989
Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:9

    Topics: Anesthetics; Animals; Antipsychotic Agents; Biomechanical Phenomena; Chloral Hydrate; Clozapine; Dibenzazepines; Dioxanes; Dopamine; Drug Combinations; Haloperidol; Idazoxan; Male; Mesencephalon; Neurons; Prazosin; Rats; Rats, Inbred Strains; Trihexyphenidyl

1985
The dopamine autoreceptor agonist B-HT 920 inhibits in vivo dopamine release into the cerebroventricular system of cats.
    European journal of pharmacology, 1987, Mar-17, Volume: 135, Issue:2

    Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Azepines; Cats; Cerebral Ventricles; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Receptors, Dopamine

1987
Activation of alpha 2-adrenoreceptors enhances haloperidol-induced suppression of operant behavior.
    Journal of neural transmission, 1986, Volume: 66, Issue:2

    Topics: Animals; Behavior, Animal; Brain Chemistry; Clonidine; Conditioning, Operant; Dihydroxyphenylalanine; Dioxanes; Drug Interactions; Haloperidol; Idazoxan; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1986
The putative dopamine autoreceptor agonist B-HT 920 decreases nigral dopamine cell firing rate and prolactin release in rat.
    Life sciences, 1985, May-13, Volume: 36, Issue:19

    Topics: Action Potentials; Animals; Azepines; Dioxanes; Dopamine; Haloperidol; Idazoxan; Iontophoresis; Male; Neurons; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Substantia Nigra; Trifluoperazine

1985
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine

1994
Regulation of extracellular dopamine by the norepinephrine transporter.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Carrier Proteins; Caudate Nucleus; Dopamine; Dopamine Antagonists; Extracellular Space; Haloperidol; Idazoxan; Indomethacin; Male; Microdialysis; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Symporters

1998
Antisecretory effect of peptide YY through neural receptors in the rat jejunum in vitro.
    Peptides, 1999, Volume: 20, Issue:8

    Topics: Animals; Atropine; Haloperidol; Hexamethonium; Idazoxan; In Vitro Techniques; Jejunum; Male; Peptide YY; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin

1999
Clozapine reversal of the deficits in coordinated movement induced by D2 receptor blockade does not depend upon antagonism of alpha2 adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:6

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Ataxia; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Idazoxan; Loxapine; Male; Muscarinic Antagonists; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Scopolamine; Yohimbine

1999
Neural mechanism of the antisecretory effect of peptide YY in the rat colon in vivo.
    Peptides, 2000, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Body Water; Colon; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Hexamethonium; Idazoxan; Intestinal Mucosa; Jejunum; Male; Nicotinic Antagonists; Peptide YY; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Vasoactive Intestinal Peptide

2000
Evidence for co-release of noradrenaline and dopamine from noradrenergic neurons in the cerebral cortex.
    Molecular psychiatry, 2001, Volume: 6, Issue:6

    Topics: 4-Butyrolactone; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebellum; Clonidine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Extracellular Space; Haloperidol; Idazoxan; Male; Microdialysis; Motor Cortex; Neurons; Norepinephrine; Prefrontal Cortex; Quinpirole; Rats; Rats, Sprague-Dawley; Solvents

2001
The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Catalepsy; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Idazoxan; Neurons; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin

2003
Alpha2-adrenoceptor antagonism is neither sufficient nor necessary for the distinctive action of atypical neuroleptics on intracranial self-stimulation in the rat.
    Behavioural pharmacology, 2003, Volume: 14, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Clonidine; Haloperidol; Idazoxan; Male; Motivation; Olanzapine; Pirenzepine; Rats; Receptors, Adrenergic, alpha-2; Self Stimulation

2003
A simple rodent assay for the in vivo identification of agents with potential to reduce levodopa-induced dyskinesia in Parkinson's disease.
    Experimental neurology, 2005, Volume: 191, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amantadine; Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Idazoxan; Levodopa; Male; Motor Activity; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reserpine

2005
Enhanced efficacy of both typical and atypical antipsychotic drugs by adjunctive alpha2 adrenoceptor blockade: experimental evidence.
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Dyskinesia, Drug-Induced; Haloperidol; Idazoxan; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Olanzapine; Prefrontal Cortex; Rats; Rats, Wistar

2007
Dopamine binds to alpha(2)-adrenergic receptors in the song control system of zebra finches (Taeniopygia guttata).
    Journal of chemical neuroanatomy, 2008, Volume: 35, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clozapine; Dopamine; Finches; Haloperidol; Homeostasis; Idazoxan; Male; Raclopride; Receptors, Adrenergic, alpha-2; Vocalization, Animal

2008
Selective enhancement of mesocortical dopaminergic transmission by noradrenergic drugs: therapeutic opportunities in schizophrenia.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:1

    Topics: Adrenergic Agents; Animals; Antipsychotic Agents; Cognition; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Haloperidol; Idazoxan; Male; Microdialysis; Molecular Targeted Therapy; Morpholines; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Reboxetine; Schizophrenia; Synaptic Transmission; Ventral Tegmental Area

2011
Clozapine reconstructed: Haloperidol's ability to reduce alcohol intake in the Syrian golden hamster can be enhanced through noradrenergic modulation by desipramine and idazoxan.
    Drug and alcohol dependence, 2015, Jul-01, Volume: 152

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Adult; Alcohol Drinking; Animals; Clozapine; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Eating; Female; Haloperidol; Humans; Idazoxan; Male; Mesocricetus; Receptors, Dopamine D2

2015