haloperidol has been researched along with glutamic acid in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (15.34) | 18.7374 |
| 1990's | 57 (34.97) | 18.2507 |
| 2000's | 42 (25.77) | 29.6817 |
| 2010's | 36 (22.09) | 24.3611 |
| 2020's | 3 (1.84) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Meanwell, NA | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Baruah, S; Davidson, AT; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Harsing, LG; Vizi, ES | 1 |
| Fukushima, R; Kizu, A; Miyagishi, T; Ono, T; Yoshida, Y | 1 |
| Dowling, JE; Knapp, AG; Schmidt, KF | 1 |
| Mataga, N; Mitsushio, H; Takashima, M; Toru, M | 1 |
| de Vries, JB; Hofsteede, RM; Tuntler, J; Westerink, BH | 1 |
| Martin, GE; Ortegón, ME; Raffa, RB; Robisch, DM | 1 |
| Schultz, W; Toan, DL | 1 |
| Gebhart, GF; Ossipov, MH | 1 |
| Dusticier, N; Kerkerian, L; Nieoullon, A | 2 |
| Suzuki, S; Yamazaki, M | 1 |
| Trulson, ME; Trulson, TJ | 1 |
| Mott, J; Sherman, AD | 2 |
| Lindefors, N; Tossman, U; Ungerstedt, U | 1 |
| Akaike, A; Hara, M; Sasa, M; Takaori, S | 1 |
| McKenzie, GM; Murphy, M; Szerb, JC; Warenycia, MW | 1 |
| Akaike, A; Ohno, Y; Sasa, M; Takaori, S | 1 |
| Kirsch, M; Kohler, K; Wagner, HJ; Weiler, R | 1 |
| Curtis, SD; Rebec, GV | 1 |
| Bartholini, G; Lloyd, KG; Scatton, B; Worms, P; Zivkovic, B | 1 |
| Fleminger, S; Hall, MD; Jenner, P; Kerwin, R; Marsden, CD; Murugaiah, K; Rupniak, NM | 1 |
| Kaiya, H; Kondo, T; Namba, M; Okada, Y; Sanpei, F; Takeuchi, K; Yoshida, H | 1 |
| Hornykiewicz, O; Kish, SJ; Perry, TL; Shannak, KS | 1 |
| Jenner, P; Kerwin, RW; Marsden, CD; Rupniak, NM | 1 |
| Mott, J; Petty, F; Sherman, AD | 1 |
| Jähkel, M; Oehler, J; Schmidt, J | 1 |
| McKenzie, GM; Murphy, MG; Szerb, JC; Warenycia, MW | 1 |
| Bowyer, JF | 1 |
| Phend, KD; Rustioni, A; Weinberg, RJ | 1 |
| Bustos, G; Jerez, S; Labarca, R; Ogalde, C; Renterías, P; Ruiz, A; Silva, H | 1 |
| Banerjee, SP; Lidsky, TI; Schneider, JS; Yablonsky-Alter, E; Zuck, LG | 1 |
| Bustos, G; Gajardo, MI; Jerez, S; Labarca, R; Ruiz, A; Seguel, M; Silva, H | 1 |
| DeCoster, MA; Klette, KL; Knight, ES; Tortella, FC | 1 |
| Palaiologos, G; Svarna, R; Tzavara, E | 1 |
| Chapman, MA; See, RE | 1 |
| Meshul, CK; Tan, SE | 1 |
| Bedingfield, JB; Calder, LD; Karler, R | 1 |
| Cotman, CW; Nguyen, L; Ułas, J | 1 |
| Boardman, P; Danevic, C; Harris, B; Mione, MC; Parnavelas, JG | 1 |
| Nash, JF; Yamamoto, BK | 1 |
| Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E; Zuck, L | 1 |
| Exposito, I; Mora, F; Porras, A; Sanz, B | 1 |
| Cooperman, MA; Yamamoto, BK | 1 |
| Janowsky, A; Meshul, CK; Stallbaumer, RK; Taylor, B | 1 |
| Kovács, KJ; Larson, AA | 1 |
| Stephans, SE; Yamamoto, BK | 1 |
| Davies, JA; Ellis, Y | 1 |
| Dietze, S; Kleim, J; Kuschinsky, K; Welsch-Kunze, S | 1 |
| Daly, DA; Moghaddam, B | 1 |
| Bunney, BS; Moghaddam, B | 1 |
| Koffel, B; Lahti, AC; LaPorte, D; Tamminga, CA | 1 |
| Lynch, AM; See, RE | 1 |
| Allen, C; Meshul, CK; Stallbaumer, RK | 1 |
| Chen, X; Hurlbert, M; Joseph, DB; Kumar, KN; Michaelis, EK; Michaelis, ML | 1 |
| Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E; Zuck, LG | 1 |
| Allen, C; Andreassen, OA; Jørgensen, HA; Meshul, CK | 1 |
| Allen, C; Bunker, GL; Janowsky, A; Mason, JN; Meshul, CK | 1 |
| Floresco, SB; Phillips, AG; Seamans, JK | 1 |
| Furtado, JC; Garside, S; Mazurek, MF | 1 |
| Amano, T; Matsubayashi, H; Sasa, M | 1 |
| Baba, A; Goji, K; Kawai, N; Moroji, T; Yamamoto, H; Yamamoto, T; Yang, X | 1 |
| Gupta, MC; Singh, J | 1 |
| Kiyatkin, EA; Rebec, GV | 1 |
| Sabel, BA; Schroeder, H; Schroeder, U | 1 |
| Grayson, DR; Li, JH; Luo, JH; Vicini, S; Wang, JF; Wang, YH; Wolfe, BB; Zhu, WJ | 1 |
| Dalia, A; Uretsky, NJ; Wallace, LJ | 1 |
| Busel, BI; Sanzharovsky, AV; Storozhuk, VM | 1 |
| Aizenman, E; Brimecombe, JC; Gallagher, MJ; Lynch, DR | 1 |
| Kratzer, U; Kretschmer, BD; Schmidt, WJ | 1 |
| Bardgett, M; Csernansky, JG; Faull, KF; Faustman, WO; Pfefferbaum, A | 1 |
| de Groat, WC; Namiki, M; Yokoyama, O; Yoshiyama, M | 1 |
| Breier, A | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Nilsson, M; Sorensen, SM; Waters, N; Waters, S | 1 |
| Arnaiz, SL; Boveris, A; Coronel, MF | 1 |
| Caron, MG; Gainetdinov, RR; Koller, BH; Mohn, AR | 1 |
| Kretschmer, BD; Schmidt, WJ; Tzschentke, TM | 1 |
| De Souza, IE; McBean, GJ; Meredith, GE | 1 |
| Baca, SM; Hyde, TM; Jaskiw, GE; Kleinman, JE; Murray, AM; Spurney, CF | 1 |
| Choe, BK; Kim, SK; Kwon, GY; Shin, SW | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Bardgett, ME; Henry, JD | 1 |
| Akbar, M; Ishihara, K; Sasa, M | 1 |
| Desole, MS; Enrico, P; Esposito, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA; Zangani, D | 1 |
| Allen, C; Meshul, CK | 1 |
| Awad, H; Bradley, SR; Conn, PJ; Levey, AI; Marino, MJ; Rouse, ST; Wittmann, M | 1 |
| Sabel, BA; Schroeder, H; Schroeder, U; Schwegler, H | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Nishikawa, H | 1 |
| Aizenman, E; Blitzblau, RC; Du, S; Leszkiewicz, DN; Rosenberg, PA; Sinor, JD; Venneti, S | 1 |
| Rebec, GV; Teagarden, MA | 1 |
| Kulkarni, SK; Naidu, PS | 1 |
| Andreassen, OA; Jørgensen, HA; Meshul, CK; Moore, C | 1 |
| Adams, BW; Moghaddam, B | 1 |
| Carlsson, A; Carlsson, ML; Nilsson, M; Waters, N; Waters, S | 1 |
| Carta, M; Covey, DF; Meyer, DA; Partridge, LD; Valenzuela, CF | 1 |
| Gonzalez, LE; Hernández, L; Paredes, D; Rada, P; Reyes, E; Rossell, S; Tucci, S | 1 |
| Bijak, M; Gołembiowska, K; Ossowska, K; Pietraszek, M; Wolfarth, S | 1 |
| Enginar, N; Koyuncuoğlu, H; Nurten, A; Nurten, R; Yamantürk, P | 1 |
| Bedogni, F; Fossati, C; Fumagalli, F; Gennarelli, M; Molteni, R; Racagni, G; Riva, MA; Roceri, M; Santero, R | 1 |
| Abercrombie, ED; Cobb, WS | 1 |
| Abekawa, T; Honda, M; Ito, K; Koyama, T | 1 |
| Bock, J; Braun, K; Gruss, M | 1 |
| Carlsson, A; Carlsson, ML; Gullme, M; Markinhuhta, KR; Nilsson, M; Pettersson, F; Sonesson, C | 1 |
| Akbarian, S; Ferris, C; Guo, Y; Konradi, C; Li, J; Schmidt, TW; Schroeder, FA; Youngs, RM | 1 |
| Bianchi, C; Calò, G; Guerrini, R; Marti, M; Mela, F; Morari, M | 1 |
| Alves, A; Burger, ME; Callegari, L; Fachineto, R; Rocha, JB | 1 |
| Wang, SJ; Yang, TT | 1 |
| Engberg, G; Erhardt, S; Linderholm, KR; Nilsson, LK; Schwieler, L | 1 |
| MacDonald, CJ; Meck, WH | 1 |
| Barrow, R; Bolognani, F; Bustillo, J; Galloway, MP; Lauriello, J; Moore, GJ; Paz, R; Perrone-Bizzozero, N; Seraji-Bozorgzad, N; Tang, J | 1 |
| Giménez-Amaya, JM; Haroutunian, V; Huerta, I; McCullumsmith, RE; Meador-Woodruff, JH | 1 |
| Barbakadze, T; Mikeladze, DG; Natsvlishvili, N; Zhuravliova, E | 1 |
| Abekawa, T; Ito, K; Koyama, T | 1 |
| Konieczny, J; Kuter, K; Ossowska, K; Pilc, A; Wardas, J | 1 |
| Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Babot, Z; López-Gil, X; Suñol, C | 1 |
| Haynes, JM; Pouton, CW; Raye, WS; Tochon-Danguy, N | 1 |
| Hatzipetros, T; Raudensky, JG; Soghomonian, JJ; Yamamoto, BK | 1 |
| Cilia, J; Hatcher, P; Jones, DN; Reavill, C | 1 |
| de Magalhães, L; Hernandes, MS; Troncone, LR | 1 |
| Dirks, P; Feigenspan, A; Trümpler, J; Weiler, R | 1 |
| Hamaguchi, T; Matsumoto, T; Motomura, E; Nakagawa, M; Ohoyama, K; Okada, M; Shiroyama, T; Suzuki, D; Tanii, H; Yamamura, S | 1 |
| Arnt, J; Mørk, A; Witten, LM | 1 |
| Mabrouk, OS; Marti, M; Morari, M | 1 |
| Bambini-Junior, V; Bobermin, LD; Gottfried, C; Quincozes-Santos, A; Riesgo, R; Tonial, RP | 1 |
| Binas, B; Fukunaga, K; Owada, Y; Shioda, N; Watanabe, M; Yamamoto, Y | 1 |
| Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P | 1 |
| Calcagno, E; Carli, M; Invernizzi, RW; Mainini, E; Mainolfi, P | 1 |
| Cecil, KM; Dunn, RS; Lindquist, DM | 1 |
| Barbier, D; Barnych, B; Lin, JS; Marinesco, S; Maucler, C; Meiller, A; Pollegioni, L; Vasylieva, N | 1 |
| Falkai, P; Gruber, O; Schmitt, A; Yeganeh-Doost, P | 1 |
| Motomura, E; Nakagawa, M; Okada, M; Tanahashi, S; Yamamura, S | 1 |
| Jardemark, K; Malmerfelt, A; Marcus, MM; Shahid, M; Svensson, TH | 1 |
| Amalric, M; Blobaum, AL; Bode, J; Bridges, TM; Bubser, M; Conn, PJ; Daniels, JS; Dickerson, JW; Engers, DW; Hopkins, CR; Italiano, K; Jadhav, S; Jones, CK; Lindsley, CW; Morrison, RD; Niswender, CM; Thompson, AD; Turle-Lorenzo, N | 1 |
| Cao, WY; Dai, RP; Li, CQ; Li, F; Li, MB; Luo, XG; Xu, Y; Zhang, JW; Zhang, JY; Zhou, XF | 1 |
| Dias, QM; Fais, RS; Petronilho, A; Prado, WA; Reis, GM | 1 |
| Ballaz, S; Fuentes, A; Morales, I; Obeso, JA; Rodriguez, M | 1 |
| Ikarashi, Y; Kanno, H; Kase, Y; Sekiguchi, K; Yamaguchi, T | 1 |
| Drummond, JB; Haroutunian, V; Meador-Woodruff, JH; Simmons, M | 1 |
| Drummond, JB; Haroutunian, V; Lucas, EK; McCullumsmith, RE; Meador-Woodruff, JH; Shan, D | 1 |
| Barbier, D; Lieutaud, T; Marinesco, S; Maucler, C; Meiller, A; Vasylieva, N; Viscogliosi, H | 1 |
| Basu, AC; Bolo, NR; Coyle, JT; Konopaske, GT; Renshaw, PF | 1 |
| Benninghoff, J; Dölzer, AL; Geiger, J; Genius, J; Giegling, I; Hartmann, AM; Möller, HJ; Rujescu, D | 1 |
| Barbosa-Silva, RC; Medeiros, P; Melo-Thomas, L; Tonelli, LC; Viana, MB | 1 |
| Dale, E; Doller, D; Gubellini, P; Kerkerian-Le Goff, L; Melon, C | 1 |
| Cui, X; Li, G; Li, M; Li, Z; Liu, F; Liu, H; Peng, L; Qin, C; Sun, D; Sun, J; Wu, J; Xu, H; Yue, Q; Zhang, J; Zhang, X; Zhu, D | 1 |
| Griesmaier, E; Hermann, M; Kiechl-Kohlendorfer, U; Obermair, GJ; Posod, A; Stanika, RI; Urbanek, M; Wechselberger, K; Wegleiter, K | 1 |
| Chaki, S; Hiyoshi, T; Kambe, D; Karasawa, J | 1 |
| Hall, K; Lewitt, M; Melkersson, K | 1 |
| Czarnecka, A; Konieczny, J; Lenda, T | 1 |
| Blobaum, AL; Bubser, M; Conn, PJ; Daniels, JS; Engers, DW; Hopkins, CR; Javitch, JA; Jones, CK; Lin, X; Lindsley, CW; Loch, MT; Niswender, CM; Rodriguez, AL; Thompson Gray, A | 1 |
| Jain, R; Meena, CL; Pant, AB; Rajput, SK; Sharma, AK; Sharma, SS | 1 |
| Fujita, Y; Hashimoto, K; Iyo, M; Kanahara, N; Nakata, Y; Niitsu, T; Oda, Y; Oishi, K; Shirayama, Y; Takase, M | 1 |
| Melo-Thomas, L; Schwarting, R; Tonelli, LC; Wöhr, M | 1 |
| Kalinina, TS; Kiselev, AV; Sergienko, VI; Stovbun, IS; Vedenkin, AS | 1 |
| Heredi, J; Holderith, N; Kis, V; Nusser, Z | 1 |
| Bhattiprolu, AK; Brzustowicz, LM; Clarke, SG; Crosta, CM; Dudzinski, NR; Firestein, BL; Fu, AY; Hernandez, K; Moore, JC; Paradiso, KG | 1 |
| Bastiampillai, T; Chan, SKW; Gregory, KJ; Langmead, CJ; Nair, PC; Tibrewal, P | 1 |
2 review(s) available for haloperidol and glutamic acid
| Article | Year |
|---|---|
Cognitive deficit in schizophrenia and its neurochemical basis.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; N-Methylaspartate; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology | 1999 |
The role of the cerebellum in schizophrenia: from cognition to molecular pathways.
Topics: Animals; Antipsychotic Agents; Cerebellum; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2011 |
2 trial(s) available for haloperidol and glutamic acid
| Article | Year |
|---|---|
Subanesthetic doses of ketamine stimulate psychosis in schizophrenia.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glutamic Acid; Haloperidol; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Psychoses, Substance-Induced; Schizophrenia; Time Factors | 1995 |
Cerebrospinal fluid glutamate inversely correlates with positive symptom severity in unmedicated male schizophrenic/schizoaffective patients.
Topics: Adult; Antipsychotic Agents; Glutamic Acid; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology | 1999 |
159 other study(ies) available for haloperidol and glutamic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Evidence of glutamatergic deficiency in schizophrenia.
Topics: Aged; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Schizophrenia; Synaptosomes; Veratridine | 1991 |
Alpha 2-adrenoceptors are not involved in the regulation of striatal glutamate release: comparison to dopaminergic inhibition.
Topics: 4-Butyrolactone; Animals; Apomorphine; Berberine; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Glutamates; Glutamic Acid; Haloperidol; Hydrazines; Hydroxydopamines; Male; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Secretory Rate; Synaptic Transmission; Yohimbine | 1991 |
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1991 |
Dopamine modulates the kinetics of ion channels gated by excitatory amino acids in retinal horizontal cells.
Topics: Analysis of Variance; Animals; Cells, Cultured; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Ion Channels; Kainic Acid; Kinetics; Neurotransmitter Agents; Perches; Retina | 1990 |
Effects of chronic treatment with trihexyphenidyl and carbamazepine alone or in combination with haloperidol on substance P content in rat brain: a possible implication of substance P in affective disorders.
Topics: Animals; Body Weight; Brain Chemistry; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Lithium; Male; Mood Disorders; Rats; Rats, Inbred Strains; Serotonin; Substance P; Trihexyphenidyl | 1988 |
Use of calcium antagonism for the characterization of drug-evoked dopamine release from the brain of conscious rats determined by microdialysis.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Calcium; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Magnesium; Male; Nomifensine; Ouabain; Piperazines; Potassium; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
In vivo demonstration of the enhancement of MK-801 by L-glutamate.
Topics: Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutamates; Glutamic Acid; Haloperidol; Kinetics; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1989 |
Responses of rat pallidum cells to cortex stimulation and effects of altered dopaminergic activity.
Topics: Animals; Cerebral Cortex; Dopamine; Fluphenazine; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glutamic Acid; Haloperidol; Male; Neural Pathways; Periodicity; Rats; Substantia Nigra; Synaptic Transmission | 1985 |
Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus.
Topics: Animals; Atropine; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Haloperidol; Injections, Spinal; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Reflex; Reticular Formation; Spinal Cord; Yohimbine | 1986 |
Modulatory effect of dopamine on high-affinity glutamate uptake in the rat striatum.
Topics: alpha-Methyltyrosine; Animals; Apomorphine; Corpus Striatum; Dopamine; Drug Synergism; Electric Stimulation; Glutamates; Glutamic Acid; Haloperidol; Hydroxydopamines; Male; Methyltyrosines; Oxidopamine; Rats; Rats, Inbred Strains; Sodium; Substantia Nigra | 1987 |
Toxicology of tremorgenic mycotoxins, fumitremorgin A and B.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Haloperidol; Harmine; Indenes; Indoles; Lethal Dose 50; Male; Mice; Perphenazine; Posture; Reserpine; Seizures; Spiperone; Triflupromazine | 1986 |
Recording of mouse ventral tegmental area dopamine-containing neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Animals; Apomorphine; Dextroamphetamine; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Homovanillic Acid; In Vitro Techniques; Male; Methyltyrosines; Mice; Tegmentum Mesencephali | 1987 |
Effects of glutaminase inhibition on release of endogenous glutamic acid.
Topics: 2-Chloroadenosine; Adenosine; Amygdala; Animals; Aspartic Acid; Diazooxonorleucine; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutaminase; Glycine; Haloperidol; In Vitro Techniques; Rats; Serotonin; Synaptosomes | 1986 |
Subchronic haloperidol and sulpiride treatment induces region-specific changes in tissue levels of putative amino acid transmitters in rat brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Haloperidol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Sulpiride | 1987 |
Acute effects of methamphetamine applied microiontophoretically to nucleus accumbens neurons in rats.
Topics: Action Potentials; Animals; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Iontophoresis; Male; Methamphetamine; Neural Pathways; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reaction Time; Reserpine; Septal Nuclei; Tegmentum Mesencephali; Thalamus | 1987 |
The effects of cortical ablation on multiple unit activity in the striatum following dexamphetamine.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; Electrophysiology; Enkephalin, Methionine; Glutamates; Glutamic Acid; Haloperidol; Male; Nerve Degeneration; Neurons, Afferent; Rats | 1987 |
Excitatory and inhibitory effects of dopamine on neuronal activity of the caudate nucleus neurons in vitro.
Topics: Action Potentials; Animals; Benzazepines; Caudate Nucleus; Domperidone; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; In Vitro Techniques; Male; Membrane Potentials; Rats; Rats, Inbred Strains | 1987 |
Glutamate and dopamine modulate synaptic plasticity in horizontal cell dendrites of fish retina.
Topics: Animals; Carps; Cyprinidae; Dendrites; Dopamine; Glutamates; Glutamic Acid; Haloperidol; In Vitro Techniques; Kainic Acid; Lighting; Microscopy, Electron; Neuronal Plasticity; Retina; Synapses | 1988 |
Reciprocal zones of excitation and inhibition in the neostriatum.
Topics: Action Potentials; Animals; Corpus Striatum; Glutamates; Glutamic Acid; Haloperidol; Male; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Direct effect of neuroleptics on glutamate release.
Topics: Amygdala; Animals; Antipsychotic Agents; Atropine; Avoidance Learning; Butaclamol; Calcium; Chlorpromazine; Clozapine; Glutamates; Glutamic Acid; Glutamine; Haloperidol; In Vitro Techniques; Male; Rats; Synaptosomes | 1984 |
Interactions between GABA, dopamine, acetylcholine, and glutamate-containing neurons in the extrapyramidal and limbic systems.
Topics: Acetylcholine; Animals; Apomorphine; Cerebral Cortex; Corpus Striatum; Dopamine; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Kinetics; Limbic System; Muscimol; Neurons; Rats | 1981 |
Long-term adaptive changes in striatal dopamine function in response to chronic neuroleptic intake in rats.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Glutamates; Glutamic Acid; Haloperidol; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1983 |
Effects of subchronic treatment of methamphetamine haloperidol on the rat brain levels of GABA, glutamate and aspartate.
Topics: Animals; Brain Chemistry; Drug Interactions; Fluorometry; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Male; Methamphetamine; Rats; Rats, Inbred Strains | 1983 |
Neuronal [3H]benzodiazepine binding and levels of GABA, glutamate, and taurine are normal in Huntington's disease cerebellum.
Topics: Amino Acids; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Humans; Huntington Disease; Middle Aged; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
A comparison of the effects of acute and one year's continuous neuroleptic treatment on the release of [3H]glutamate and [3H]acetylcholine from rat striatal slices.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Calcium; Clozapine; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Haloperidol; In Vitro Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Sulpiride; Trifluoperazine | 1984 |
Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum.
Topics: Afferent Pathways; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Kinetics; Neural Inhibition; Rats; Receptors, Dopamine; Substantia Nigra; Synapses; Synaptic Transmission | 1983 |
Potential locus and mechanism of blockade of conditioned avoidance responding by neuroleptics.
Topics: Amygdala; Animals; Antipsychotic Agents; Avoidance Learning; Chlorpromazine; Glutamates; Glutamic Acid; Glutamine; Haloperidol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Thioridazine | 1984 |
[Development of tolerance to haloperidol in the rat striatum].
Topics: Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Glutamates; Glutamic Acid; Haloperidol; Male; Rats; Rats, Inbred Strains | 1984 |
Bilateral ablation of the corticostriatal projection: behavioral, biochemical and electrophysiological correlates.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; Electrophysiology; Glutamates; Glutamic Acid; Haloperidol; Male; Neural Pathways; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1984 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
An osmium-free method of epon embedment that preserves both ultrastructure and antigenicity for post-embedding immunocytochemistry.
Topics: Animals; Antigens; Brain; Calcitonin Gene-Related Peptide; Epoxy Resins; gamma-Aminobutyric Acid; Glutamic Acid; Glutaral; Histological Techniques; Male; Microscopy, Immunoelectron; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Osmium; Preservation, Biological; Rats; Rats, Sprague-Dawley; Substance P | 1995 |
Effects of haloperidol on CSF glutamate levels in drug-naive schizophrenic patients.
Topics: Adolescent; Adult; Dopamine Antagonists; Female; Glutamic Acid; Haloperidol; Humans; Male; Schizophrenia | 1995 |
Taurine prevents haloperidol-induced changes in striatal neurochemistry and behavior.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Drug Administration Schedule; Evaluation Studies as Topic; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Taurine | 1995 |
Effects of D-amphetamine administration on the release of endogenous excitatory amino acids in the rat nucleus accumbens.
Topics: Amphetamine; Animals; Aspartic Acid; Excitatory Amino Acids; Glutamic Acid; Haloperidol; Injections, Intravenous; Male; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1995 |
Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures.
Topics: Animals; Calcium; Cells, Cultured; Cyclazocine; Cyclopentanes; Dextromethorphan; Glutamic Acid; Guanidines; Haloperidol; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Pentazocine; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Haloperidol reduces K(+)-evoked Ca(2+)-dependent D-[3H]aspartate release from rat hippocampal slices.
Topics: Animals; Aspartic Acid; Calcium; Glutamic Acid; Haloperidol; Hippocampus; In Vitro Techniques; Male; Potassium; Rats; Rats, Wistar; Synaptic Transmission; Tritium | 1995 |
Chronic haloperidol, but not clozapine, produces altered oral movements and increased extracellular glutamate in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Behavior, Animal; Clozapine; Corpus Striatum; Electric Stimulation; Female; Fourier Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Image Processing, Computer-Assisted; Microdialysis; Motor Activity; Rats; Rats, Sprague-Dawley | 1994 |
Haloperidol-induced morphological alterations are associated with changes in calcium/calmodulin kinase II activity and glutamate immunoreactivity.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Caudate Nucleus; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Synapses | 1994 |
Cocaine behavioral sensitization and the excitatory amino acids.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Haloperidol; Male; Mice; Neuroeffector Junction; Receptors, GABA-A; Seizures; Stereotyped Behavior | 1994 |
Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex.
Topics: Analysis of Variance; Animals; Autoradiography; Glutamates; Glutamic Acid; Haloperidol; Male; Mice; Parietal Lobe; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1993 |
Lineage analysis reveals neurotransmitter (GABA or glutamate) but not calcium-binding protein homogeneity in clonally related cortical neurons.
Topics: Animals; Aspartic Acid; Calcium-Binding Proteins; Cell Line; Cerebral Cortex; Clone Cells; Epoxy Resins; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Immunohistochemistry; Neurons; Phthalic Anhydrides; Rats; Rats, Sprague-Dawley; Tissue Embedding | 1994 |
Effect of D-amphetamine on the extracellular concentrations of glutamate and dopamine in iprindole-treated rats.
Topics: alpha-Methyltyrosine; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Iprindole; Male; Methyltyrosines; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 1993 |
Anti-glutamatergic effects of clozapine.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Humans; Membrane Potentials; Rats; Vibrissae | 1993 |
Effects of apomorphine and L-methionine sulphoximine on the release of excitatory amino acid neurotransmitters and glutamine in the striatum of the conscious rat.
Topics: Analysis of Variance; Animals; Apomorphine; Aspartic Acid; Corpus Striatum; Glutamates; Glutamic Acid; Glutamine; Haloperidol; Kinetics; Male; Methionine Sulfoximine; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1994 |
Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Dopamine; Extracellular Space; Glutamates; Glutamic Acid; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Osmolar Concentration; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Haloperidol-induced morphological changes in striatum are associated with glutamate synapses.
Topics: Animals; Benzazepines; Dizocilpine Maleate; Glutamic Acid; Haloperidol; Immunohistochemistry; Injections; Male; Microscopy, Electron; Neostriatum; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Density of NMDA-coupled and uncoupled 1-[1-(2-[3H]thienyl) cyclohexyl]piperidine recognition sites in the brain and spinal cord: differential effects of NMDA agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Dizocilpine Maleate; Glutamic Acid; Glycine; Haloperidol; Male; Mice; N-Methylaspartate; Phencyclidine; Spinal Cord; Tritium | 1994 |
Methamphetamine-induced neurotoxicity: roles for glutamate and dopamine efflux.
Topics: Animals; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Extracellular Space; Glutamic Acid; Haloperidol; Male; Methamphetamine; Microdialysis; Nervous System Diseases; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley | 1994 |
The effects of sigma ligands on the release of glutamate from rat striatal slices.
Topics: Animals; Corpus Striatum; Female; Glutamic Acid; Haloperidol; In Vitro Techniques; Ligands; Neuropeptide Y; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, sigma | 1994 |
Recordings of extracellular glutamate and gamma-aminobutyric acid in the striatum of non-anesthetized rats. K(+)-stimulation, its Ca(2+)-dependence and lack of effects of drugs acting on dopamine receptors.
Topics: Animals; Apomorphine; Calcium; Corpus Striatum; Dialysis; Ergolines; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Male; Potassium; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Stimulation, Chemical | 1993 |
Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats.
Topics: Animals; Aspartic Acid; Clozapine; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley | 1993 |
Depolarization inactivation of dopamine neurons: terminal release characteristics.
Topics: Anesthesia, General; Animals; Aspartic Acid; Consciousness; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Male; Microdialysis; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Reference Values | 1993 |
Chronic haloperidol potentiates stimulated glutamate release in caudate putamen, but not prefrontal cortex.
Topics: Animals; Antipsychotic Agents; Basal Metabolism; Caudate Nucleus; Drug Implants; Drug Synergism; Female; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Microdialysis; Potassium; Prefrontal Cortex; Putamen; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1995 |
GM1 ganglioside administration partially counteracts the morphological changes associated with haloperidol treatment within the dorsal striatum of the rat.
Topics: Animals; Corpus Striatum; Gangliosides; Glutamic Acid; Haloperidol; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 1995 |
Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex.
Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Haloperidol; Illicit Drugs; Kinetics; Male; Membrane Proteins; N-Methylaspartate; Phencyclidine; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Spermidine; Synaptic Membranes; Tritium | 1996 |
Glutamate agonist activity: implications for antipsychotic drug action and schizophrenia.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Schizophrenia | 1995 |
Correlation of vacuous chewing movements with morphological changes in rats following 1-year treatment with haloperidol.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Caudate Nucleus; Dyskinesia, Drug-Induced; Female; Glutamic Acid; Haloperidol; Rats; Rats, Sprague-Dawley; Synapses | 1996 |
Effects of subchronic clozapine and haloperidol on striatal glutamatergic synapses.
Topics: Alternative Splicing; Animals; Base Sequence; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Genetic Variation; Glutamic Acid; Haloperidol; In Situ Hybridization; Ion Channels; Macromolecular Substances; Male; Microscopy, Immunoelectron; Nerve Endings; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA Probes; Synapses | 1996 |
A selective role for dopamine in the nucleus accumbens of the rat in random foraging but not delayed spatial win-shift-based foraging.
Topics: Animals; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Feeding Behavior; Glutamic Acid; Haloperidol; Male; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Space Perception | 1996 |
Dopamine-glutamate interactions in the striatum: behaviourally relevant modification of excitotoxicity by dopamine receptor-mediated mechanisms.
Topics: Analysis of Variance; Animals; Corpus Striatum; Dopamine; Functional Laterality; Glutamic Acid; Haloperidol; Male; Maze Learning; Motor Activity; Neurotoxins; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Substantia Nigra | 1996 |
Hypersensitivity of nucleus accumbens neurons to methamphetamine and dopamine following repeated administrations of methamphetamine.
Topics: Action Potentials; Animals; Dopamine; Glutamic Acid; Haloperidol; Iontophoresis; Methamphetamine; Neurons; Nucleus Accumbens; Rats; Rats, Wistar | 1996 |
Non-aminergic effects of amphetamine on the NMDA receptor in primary cultured cortical cells.
Topics: Amphetamines; Animals; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Haloperidol; Phencyclidine; Protein Kinases; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1996 |
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperature; Catalepsy; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Haloperidol; Hypothermia; Injections, Subcutaneous; Ketamine; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Reserpine; Trifluoperazine | 1997 |
Iontophoresis of amphetamine in the neostriatum and nucleus accumbens of awake, unrestrained rats.
Topics: Action Potentials; Amphetamine; Animals; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Glutamic Acid; Haloperidol; Iontophoresis; Male; Membrane Potentials; Neostriatum; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Regression Analysis; Wakefulness | 1997 |
The role of striatal glutamatergic system in haloperidol-induced dopamine receptor supersensitivity and effects of monosialoganglioside GM1.
Topics: Animals; Aspartic Acid; Dopamine Antagonists; G(M1) Ganglioside; Glutamic Acid; Haloperidol; Male; Neostriatum; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Glutamate; Spiperone | 1997 |
Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors.
Topics: Antibodies, Monoclonal; Antibody Specificity; Cell Line; Cysteic Acid; DNA, Complementary; Fluorescent Antibody Technique, Indirect; Genes, Reporter; Glutamic Acid; Haloperidol; Humans; Kidney; Membrane Potentials; Patch-Clamp Techniques; Protein Conformation; Protein Multimerization; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; RNA Splicing; Transfection | 1998 |
Dopaminergic agonists administered into the nucleus accumbens: effects on extracellular glutamate and on locomotor activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Benzazepines; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Dopamine Antagonists; Glutamic Acid; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Salicylamides | 1998 |
Interaction between dopamine and glutamate in the sensorimotor cortex during conditioned placing reaction.
Topics: Amphetamine; Animals; Behavior, Animal; Cats; Conditioning, Classical; Dopamine; Glutamic Acid; Haloperidol; Levodopa; Male; Neocortex | 1998 |
An NR2B point mutation affecting haloperidol and CP101,606 sensitivity of single recombinant N-methyl-D-aspartate receptors.
Topics: Animals; Arginine; CHO Cells; Cricetinae; Dizocilpine Maleate; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Iodine Radioisotopes; Piperidines; Point Mutation; Receptors, N-Methyl-D-Aspartate | 1998 |
Riluzole, a glutamate release inhibitor, and motor behavior.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Catalepsy; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Locomotion; Male; Motor Activity; N-Methylaspartate; Neuropsychological Tests; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Riluzole; Smell | 1998 |
Glutamatergic and dopaminergic contributions to rat bladder hyperactivity after cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Benzazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Haloperidol; Rats; Rats, Sprague-Dawley; Sulpiride; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists | 1999 |
Nitric oxide, superoxide, and hydrogen peroxide production in brain mitochondria after haloperidol treatment.
Topics: Animals; Brain; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Hydrogen Peroxide; Injections, Intraperitoneal; Kinetics; Malates; Mice; Mitochondria; Nitric Oxide; Oxygen Consumption; Submitochondrial Particles; Substrate Specificity; Succinates; Superoxides | 1999 |
Mice with reduced NMDA receptor expression display behaviors related to schizophrenia.
Topics: Animals; Antipsychotic Agents; Antisocial Personality Disorder; Behavior, Animal; Calcium Signaling; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Haloperidol; Male; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenic Psychology; Serotonin Antagonists; Sexual Behavior, Animal; Social Behavior; Stereotyped Behavior | 1999 |
State-dependent blockade of haloperidol-induced sensitization of catalepsy by MK-801.
Topics: Animals; Antipsychotic Agents; Catalepsy; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Chronic haloperidol treatment impairs glutamate transport in the rat striatum.
Topics: Animals; Aspartic Acid; Biological Transport; Corpus Striatum; Dopamine Antagonists; Glutamic Acid; Haloperidol; Male; Rats; Rats, Wistar; Synaptosomes; Tritium | 1999 |
Differential effects of haloperidol and clozapine on ionotropic glutamate receptors in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Aspartic Acid; Binding Sites; Brain; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1999 |
Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells.
Topics: Animals; Dopamine; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Haloperidol; Kainic Acid; Muscimol; Neuropeptide Y; Pentylenetetrazole; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
Locomotor activity and accumbens Fos expression driven by ventral hippocampal stimulation require D1 and D2 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Benzazepines; Brain Chemistry; Cycloleucine; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Agonists; Genes, Immediate-Early; Glutamic Acid; Haloperidol; Hippocampus; Kainic Acid; Lidocaine; Locomotion; Male; N-Methylaspartate; Neural Pathways; Neuroprotective Agents; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1999 |
[Effects of OPC-24439, a sigma ligand, on neuronal activities in the hippocampus].
Topics: Animals; Benzylamines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Antagonism; Glutamic Acid; Haloperidol; Hippocampus; In Vitro Techniques; Ligands; Male; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, sigma | 1999 |
On the mechanism of d-amphetamine-induced changes in glutamate, ascorbic acid and uric acid release in the striatum of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Dextroamphetamine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Glutamic Acid; Haloperidol; In Vitro Techniques; Injections; Male; Microdialysis; Motor Activity; Neostriatum; Oxidation-Reduction; Rats; Rats, Wistar; Stereotaxic Techniques; Stereotyped Behavior; Uric Acid | 2000 |
Haloperidol reverses the changes in striatal glutamatergic immunolabeling following a 6-OHDA lesion.
Topics: Animals; Apomorphine; Denervation; Dopamine Agonists; Dopamine Antagonists; Glutamic Acid; Haloperidol; Immunohistochemistry; Male; Motor Cortex; Neostriatum; Nerve Degeneration; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia Nigra pars reticulata.
Topics: Animals; Bridged Bicyclo Compounds; Catalepsy; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Haloperidol; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Substantia Nigra; Subthalamic Nucleus | 2000 |
Neuroleptics ameliorate phencyclidine-induced impairments of short-term memory.
Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Interneurons; Male; Memory Disorders; Memory, Short-Term; Phencyclidine; Rats; Risperidone; Schizophrenia; Spiperone | 2000 |
Involvement of direct inhibition of NMDA receptors in the effects of sigma-receptor ligands on glutamate neurotoxicity in vitro.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Haloperidol; Ligands; Neurons; Neuroprotective Agents; Phenazocine; Propylamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; RNA, Messenger | 2000 |
NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Cell Death; Cells, Cultured; Cerebral Cortex; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Intracellular Fluid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Effects of long-term haloperidol treatment on glutamate-evoked ascorbate release in rat striatum.
Topics: Animals; Ascorbic Acid; Corpus Striatum; Dopamine Antagonists; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors | 2001 |
Excitatory mechanisms in neuroleptic-induced vacuous chewing movements (VCMs): possible involvement of calcium and nitric oxide.
Topics: Animals; Antipsychotic Agents; Calcium; Dyskinesia, Drug-Induced; Glutamic Acid; Haloperidol; Male; Mastication; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Stereotyped Behavior | 2001 |
Oral dyskinesias and morphological changes in rat striatum during long-term haloperidol administration.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Dyskinesia, Drug-Induced; Female; Glutamic Acid; Haloperidol; Immunohistochemistry; Mastication; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Synapses | 2001 |
Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex.
Topics: Animals; Clozapine; Fluorobenzenes; Glutamic Acid; Haloperidol; Male; Microdialysis; Phencyclidine; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2001 |
A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Piperidines; Risperidone; Serotonin Antagonists | 2001 |
Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors.
Topics: Animals; Animals, Newborn; Binding Sites; Cells, Cultured; Central Nervous System; Chelating Agents; Egtazic Acid; Electrophysiology; Glutamic Acid; Haloperidol; Hippocampus; Neurons; Pertussis Toxin; Pregnenolone; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Steroids; Virulence Factors, Bordetella | 2002 |
Haloperidol abolished glutamate release evoked by photic stimulation of the visual cortex in rats.
Topics: Animals; Dopamine Antagonists; Electrophoresis; Extracellular Space; Glutamic Acid; Haloperidol; Male; Microdialysis; Photic Stimulation; Rats; Rats, Wistar; Visual Cortex | 2002 |
Differential effects of chronic haloperidol and clozapine administration on glutamatergic transmission in the fronto-parietal cortex in rats: microdialysis and electrophysiological studies.
Topics: Animals; Aspartic Acid; Clozapine; Electrophysiology; Frontal Lobe; Glutamic Acid; Haloperidol; Male; Microdialysis; Parietal Lobe; Rats; Rats, Wistar | 2002 |
Scopolamine-induced convulsions in fasted mice after food intake: determination of blood glucose levels, [3H]glutamate binding kinetics and antidopaminergic drug effects.
Topics: Animals; Blood Glucose; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Eating; Fasting; Glutamic Acid; Haloperidol; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Random Allocation; Reaction Time; Scopolamine; Seizures | 2003 |
Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Male; Neuronal Plasticity; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Transmission | 2003 |
Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent.
Topics: Animals; Dendrites; Dopamine; Dopamine Antagonists; Drug Synergism; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Haloperidol; Male; Microdialysis; Muscimol; Neural Inhibition; Neural Pathways; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission | 2003 |
Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Chromatography, High Pressure Liquid; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Haloperidol; Male; Microdialysis; Motor Activity; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Stereotyped Behavior; Thiazoles; Time Factors | 2003 |
Haloperidol impairs auditory filial imprinting and modulates monoaminergic neurotransmission in an imprinting-relevant forebrain area of the domestic chick.
Topics: Acoustic Stimulation; Amino Acids; Animals; Auditory Perception; Behavior, Animal; Biogenic Monoamines; Chickens; Discrimination, Psychological; Extracellular Fluid; Female; Glutamic Acid; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Imprinting, Psychological; Male; Microdialysis; N-Methylaspartate; Prosencephalon; Synaptic Transmission; Taurine | 2003 |
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.
Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Grooming; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Piperidines; Schizophrenia | 2004 |
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling.
Topics: Acetylation; Animals; Animals, Newborn; Blotting, Southern; Blotting, Western; Chromatin Assembly and Disassembly; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Genes, fos; Glial Fibrillary Acidic Protein; Glutamic Acid; Haloperidol; Histones; Immunohistochemistry; In Vitro Techniques; Indoles; Isoquinolines; Male; Methylation; Mice; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thionucleotides; Time Factors | 2004 |
Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release.
Topics: Animals; Dopamine Antagonists; Dyskinesia, Drug-Induced; Glutamic Acid; Haloperidol; Male; Microdialysis; Nociceptin; Opioid Peptides; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2004 |
Acute reserpine and subchronic haloperidol treatments change synaptosomal brain glutamate uptake and elicit orofacial dyskinesia in rats.
Topics: Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Drug Administration Schedule; Dyskinesia, Drug-Induced; Glutamic Acid; Haloperidol; Male; Mastication; Rats; Rats, Wistar; Reserpine; Synaptosomes; Tongue | 2005 |
Effects of haloperidol and clozapine on glutamate release from nerve terminals isolated from rat prefrontal cortex.
Topics: Animals; Clozapine; Dose-Response Relationship, Drug; Glutamic Acid; Haloperidol; Male; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley | 2005 |
Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms.
Topics: Action Potentials; Analysis of Variance; Animals; Antipsychotic Agents; Butyrates; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Kynurenic Acid; Locus Coeruleus; Male; Neurons; Norepinephrine; Quinolones; Rats; Rats, Sprague-Dawley | 2005 |
Differential effects of clozapine and haloperidol on interval timing in the supraseconds range.
Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Haloperidol; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin; Time Perception | 2005 |
Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Dopamine Antagonists; Drug Administration Schedule; Glutamic Acid; Glutamine; Haloperidol; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley | 2006 |
Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia.
Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Clozapine; COP9 Signalosome Complex; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Guanine Nucleotide Exchange Factors; Haloperidol; Heat-Shock Proteins; Humans; Image Processing, Computer-Assisted; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Male; Membrane Transport Proteins; Middle Aged; Rats; Rats, Sprague-Dawley; Rho Guanine Nucleotide Exchange Factors; RNA, Messenger; Schizophrenia; Thalamus; Transcription, Genetic | 2006 |
Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity.
Topics: Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Dizocilpine Maleate; Glutamic Acid; Haloperidol; L-Lactate Dehydrogenase; Neuroglia; Neurons; Nitric Oxide Synthase Type I; ras-GRF1; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2007 |
Role of the simultaneous enhancement of NMDA and dopamine D1 receptor-mediated neurotransmission in the effects of clozapine on phencyclidine-induced acute increases in glutamate levels in the rat medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Drug Resistance; Glutamic Acid; Haloperidol; Humans; Male; Microdialysis; Motor Activity; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2006 |
The influence of group III metabotropic glutamate receptor stimulation by (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid on the parkinsonian-like akinesia and striatal proenkephalin and prodynorphin mRNA expression in rats.
Topics: Animals; Corpus Striatum; Cyclopentanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Enkephalins; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glutamic Acid; Haloperidol; Male; Neural Pathways; Opioid Peptides; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger; Substantia Nigra; Synaptic Transmission; Tricarboxylic Acids; Up-Regulation | 2007 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Schizophrenia; Serotonin; Synaptic Transmission | 2007 |
Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Atropine; Calcium; Cell Differentiation; Cells, Cultured; Cholinergic Agents; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Embryonic Stem Cells; Fluorescent Dyes; Glutamic Acid; Haloperidol; Mice; Microtubule-Associated Proteins; Muscarinic Antagonists; Neurons; Norepinephrine; Phenotype; Tetrodotoxin; Tritium; Tyrosine 3-Monooxygenase | 2007 |
Haloperidol treatment after high-dose methamphetamine administration is excitotoxic to GABA cells in the substantia nigra pars reticulata.
Topics: Animals; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Methamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substantia Nigra; Time Factors | 2007 |
(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Ketamine; Lamotrigine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone; Schizophrenia; Sulfonamides; Thiophenes; Triazines | 2007 |
Glycine stimulates the release of labeled acetylcholine but not dopamine nor glutamate from superfused rat striatal tissue.
Topics: Acetylcholine; Analysis of Variance; Animals; Antipsychotic Agents; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Glycine Agents; Haloperidol; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Tritium | 2007 |
Ether-à-gogo-related gene (erg1) potassium channels shape the dark response of horizontal cells in the mammalian retina.
Topics: Animals; Axons; Cisapride; Darkness; Electrophysiological Phenomena; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Glutamic Acid; Haloperidol; Immunohistochemistry; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Retinal Horizontal Cells; Synapses; Terfenadine; Tetraethylammonium | 2009 |
Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex.
Topics: Action Potentials; Animals; Antipsychotic Agents; Biogenic Monoamines; Dibenzothiepins; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Locus Coeruleus; Male; Mediodorsal Thalamic Nucleus; Neurons; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2009 |
Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Dopamine; Dopamine D2 Receptor Antagonists; Drug Synergism; Extracellular Space; Fluorobenzenes; Glutamic Acid; Haloperidol; Imidazoles; Indoles; Male; Microdialysis; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Antagonists | 2009 |
Endogenous nociceptin/orphanin FQ (N/OFQ) contributes to haloperidol-induced changes of nigral amino acid transmission and parkinsonism: a combined microdialysis and behavioral study in naïve and nociceptin/orphanin FQ receptor knockout mice.
Topics: Animals; Antipsychotic Agents; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Narcotic Antagonists; Neuropharmacology; Nociceptin; Nociceptin Receptor; Opioid Peptides; Parkinsonian Disorders; Piperidines; Receptors, Opioid; Substantia Nigra; Synaptic Transmission | 2010 |
Effects of atypical (risperidone) and typical (haloperidol) antipsychotic agents on astroglial functions.
Topics: Animals; Antipsychotic Agents; Astrocytes; Brain Chemistry; Cell Line; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Haloperidol; Humans; Reactive Oxygen Species; Risperidone; Schizophrenia | 2010 |
Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain.
Topics: Acetylcholine; Animals; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Catalepsy; Cell Line, Tumor; Dopamine; Extracellular Signal-Regulated MAP Kinases; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Glutamic Acid; Haloperidol; Humans; Immunohistochemistry; Interneurons; Ligands; Methamphetamine; Mice; Mice, Knockout; Neostriatum; Phosphorylation; Protein Binding; Receptors, Dopamine D2; Synaptic Transmission | 2010 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines; Choice Behavior; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Impulsive Behavior; Male; Microdialysis; Neuropsychological Tests; Olanzapine; Piperazines; Prefrontal Cortex; Quinolones; Rats; Reaction Time; Schizophrenia; Serotonin; Time Factors | 2011 |
Long term antipsychotic treatment does not alter metabolite concentrations in rat striatum: an in vivo magnetic resonance spectroscopy study.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aspartic Acid; Choline; Clozapine; Corpus Striatum; Creatine; Dose-Response Relationship, Drug; Glutamic Acid; Haloperidol; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley | 2011 |
Covalent enzyme immobilization by poly(ethylene glycol) diglycidyl ether (PEGDE) for microelectrode biosensor preparation.
Topics: Amino Acid Oxidoreductases; Animals; Biosensing Techniques; Brain Chemistry; Cross-Linking Reagents; D-Amino-Acid Oxidase; Enzymes, Immobilized; Epoxy Resins; Fixatives; Glucose; Glucose Oxidase; Glutamic Acid; Glutaral; Male; Rats; Rats, Wistar; Serine | 2011 |
Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes.
Topics: Animals; Antipsychotic Agents; Astrocytes; Cells, Cultured; Citrates; Clozapine; Glutamic Acid; Haloperidol; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Tetanus Toxin; Tetrodotoxin | 2012 |
Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Drug Synergism; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Membrane Potentials; Olanzapine; Oxadiazoles; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Synaptic Transmission; Tetrahydronaphthalenes | 2012 |
The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Brain; Calcium Signaling; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Haloperidol; HEK293 Cells; Humans; Levodopa; Male; Monoamine Oxidase; Motor Neuron Disease; Oxidopamine; Parkinson Disease; Picolinic Acids; Protein Binding; Psychomotor Performance; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Substantia Nigra; Thallium; Transfection; Triazoles; Tyrosine 3-Monooxygenase | 2012 |
A simple method for detection of food foraging behavior in the rat: involvement of NMDA and dopamine receptors in the behavior.
Topics: Animals; Behavior, Animal; Competitive Behavior; Dopamine; Dopamine Antagonists; Feeding Behavior; Female; Glutamic Acid; Haloperidol; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate | 2012 |
Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Pain; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Subthalamic Nucleus; Subthalamus | 2012 |
Striatal interaction among dopamine, glutamate and ascorbate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Ascorbic Acid; Basal Ganglia Diseases; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Dopamine Antagonists; Electrochemistry; Fluorometry; Glutamic Acid; Haloperidol; Levodopa; Male; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley | 2012 |
Ameliorative effect of yokukansan on vacuous chewing movement in haloperidol-induced rat tardive dyskinesia model and involvement of glutamatergic system.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Drugs, Chinese Herbal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Transporter 2; Glutamic Acid; Haloperidol; Humans; Male; Mastication; Movement; Rats; Rats, Wistar; Treatment Outcome | 2012 |
Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.
Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Egg Proteins; Female; Frontal Lobe; Gene Expression Regulation; Genetic Markers; Genetic Predisposition to Disease; Glutamic Acid; Haloperidol; Humans; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Prefrontal Cortex; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Schizophrenia; Synaptic Transmission; Up-Regulation | 2012 |
Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia.
Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Haloperidol; Hippocampus; Humans; Male; Rats; Rats, Sprague-Dawley; Schizophrenia; Temporal Lobe; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2; Vesicular Glutamate Transport Proteins | 2013 |
Immobilization method to preserve enzyme specificity in biosensors: consequences for brain glutamate detection.
Topics: Amino Acid Oxidoreductases; Animals; Biosensing Techniques; Brain; Enzymes, Immobilized; Epoxy Resins; Glucose Oxidase; Glutamic Acid; Male; Microelectrodes; Rats; Rats, Wistar; Substrate Specificity | 2013 |
Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain.
Topics: Animals; Antipsychotic Agents; Astrocytes; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Haloperidol; Homeostasis; Magnetic Resonance Spectroscopy; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Schizophrenia; Time Factors | 2013 |
Glutamatergic dysbalance and oxidative stress in in vivo and in vitro models of psychosis based on chronic NMDA receptor antagonism.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Hippocampus; Male; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tyrosine | 2013 |
Glutamatergic neurotransmission in the inferior colliculus influences intrastriatal haloperidol-induced catalepsy.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; N-Methylaspartate; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2014 |
Distinct effects of mGlu4 receptor positive allosteric modulators at corticostriatal vs. striatopallidal synapses may differentially contribute to their antiparkinsonian action.
Topics: Amino Acid Transport System X-AG; Anilides; Animals; Antiparkinson Agents; Brain; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dopamine Antagonists; Excitatory Amino Acid Agents; Globus Pallidus; Glutamic Acid; Haloperidol; Male; Oxidopamine; Parkinsonian Disorders; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tissue Culture Techniques | 2014 |
Paliperidone protects SK-N-SH cells against glutamate toxicity via Akt1/GSK3β signaling pathway.
Topics: Antipsychotic Agents; Apoptosis; Cell Enlargement; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Inhibitors; Gene Expression; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Haloperidol; Humans; Isoxazoles; L-Lactate Dehydrogenase; Morpholines; Neuroprotective Agents; Paliperidone Palmitate; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidines; Reactive Oxygen Species; RNA, Messenger; Signal Transduction | 2014 |
The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial membrane potential in vitro and inhibiting microglial activation in vivo.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Caspase 3; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glycoproteins; Haloperidol; Hippocampus; Ibotenic Acid; Membrane Potential, Mitochondrial; Mice; Microglia; Neurons; Receptors, sigma; Sigma-1 Receptor; Statistics, Nonparametric | 2014 |
Involvement of glutamatergic and GABAergic transmission in MK-801-increased gamma band oscillation power in rat cortical electroencephalograms.
Topics: Amino Acids; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Excitatory Amino Acid Antagonists; Fluorobenzenes; GABA Agents; Gamma Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Riluzole; Triazoles | 2014 |
Higher serum concentrations of tyrosine and glutamate in schizophrenia patients treated with clozapine, compared to in those treated with conventional antipsychotics.
Topics: Adult; Amino Acids; Antipsychotic Agents; Chromatography, Ion Exchange; Clopenthixol; Clozapine; Cohort Studies; Female; Glutamic Acid; Haloperidol; Humans; Insulin Resistance; Male; Middle Aged; Perphenazine; Prospective Studies; Psychotic Disorders; Schizophrenia; Thioridazine; Tyrosine | 2015 |
Early increase in dopamine release in the ipsilateral striatum after unilateral intranigral administration of lactacystin produces spontaneous contralateral rotations in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Amphetamine; Animals; Benzazepines; Central Nervous System Agents; Corpus Striatum; Dopamine; Dopamine Antagonists; Functional Laterality; Glutamic Acid; Haloperidol; Homovanillic Acid; Male; Movement; Parkinsonian Disorders; Rats, Wistar; Receptors, Dopamine; Rotation; Substantia Nigra | 2016 |
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers.
Topics: Allosteric Regulation; Animals; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Brain; Catalepsy; Disease Models, Animal; Dopamine Agonists; Forelimb; Glutamic Acid; Haloperidol; HEK293 Cells; Humans; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Transfection | 2016 |
Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Catalepsy; Cell Death; Disease Models, Animal; Glucose; Glutamic Acid; Haloperidol; Hippocampus; Inflammation Mediators; Lipid Peroxidation; Male; Memory Disorders; Mice; Models, Biological; Motor Activity; Neurons; Oxygen; PC12 Cells; Rats; Scopolamine; Thyrotropin-Releasing Hormone | 2016 |
Alterations in glutamatergic signaling in the brain of dopamine supersensitivity psychosis and non-supersensitivity psychosis model rats.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Haloperidol; Infusion Pumps, Implantable; Male; Psychotic Disorders; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2017 |
Paradoxical kinesia induced by appetitive 50-kHz ultrasonic vocalizations in rats depends on glutamatergic mechanisms in the inferior colliculus.
Topics: Animals; Appetitive Behavior; Catalepsy; Diazepam; Disease Models, Animal; GABA Modulators; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; N-Methylaspartate; Neurotransmitter Agents; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ultrasonics; Vocalization, Animal | 2018 |
Calcium Salt of N-(5-Hydroxynicotinoyl)-L-Glutamic Acid Weakens Depressive-Like Behavior and Parkinsonian Syndrome in Experiment on Rodents.
Topics: Animals; Antidepressive Agents; Calcium; Catalepsy; Depression; Glutamic Acid; Haloperidol; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders | 2019 |
A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses.
Topics: Animals; Epoxy Resins; Glutamic Acid; Humans; Immunohistochemistry; Microscopy, Confocal; Synapses | 2020 |
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis.
Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Clozapine; Dendrites; Drug Evaluation, Preclinical; Fluphenazine; Gene Expression Regulation; Glutamic Acid; Haloperidol; Humans; Induced Pluripotent Stem Cells; Ion Channels; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Isoforms; Schizophrenia; Serine | 2020 |
Does clozapine treat antipsychotic-induced behavioural supersensitivity through glutamate modulation within the striatum?
Topics: Antipsychotic Agents; Clozapine; Corpus Striatum; Glutamic Acid; Haloperidol | 2023 |