haloperidol and flunitrazepam

haloperidol has been researched along with flunitrazepam in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's6 (24.00)18.2507
2000's9 (36.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Machen, VL; Swaiman, KF1
Akaike, N; Kaneda, M; Oyama, Y; Wakamori, M1
Becker, D; Gavish, M; Tanne, Z; Weizman, R1
Komulainen, H; Tuomisto, J1
Horton, RW; Jenner, P; Marsden, CD; Prestwich, SA; Rupniak, NM1
Hornykiewicz, O; Kish, SJ; Perry, TL; Shannak, KS1
Ovtcharov, R; Petkov, VV1
Zharkovskaia, TA; Zharkovskiĭ, AM1
Mol, CA; Schinkel, AH; van Deemter, L; Wagenaar, E1
Blum, S; Brummer, G; Dubisz, N; Funk, W; Hannemann, L; Müller, C; Rommelspacher, H; Specht, M; Spies, CD; Striebel, HW1
Furukori, H; Hayashi, K; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Tokinaga, N; Yasui, N1
Aizenberg, D; Dorevitch, A; Katz, N; Weizman, A; Zemishlany, Z1
Lenzenhuber, E; Müller, C; Rommelspacher, H; Spies, C1
Asukai, N; Hatta, K; Matsuzaki, I; Nakamura, H; Takahashi, T; Yamashiro, H; Yonezawa, Y1
Hüske, B; Kox, WJ; Lenzenhuber, E; Neumann, T; Otter, HE; Rettig, J; Sellers, EM; Sinha, P; Spies, CD1
Abe, T; Kajii, E; Kato, S; Konno, T; Matsumoto, M; Tamba, K1
Watari, M1
Hinton, T; Johnston, GA; O'Reilly, JN; Skilbeck, KJ2
Furuta, K; Hamakawa, H; Hatta, K; Hirata, T; Kawabata, T; Nakamura, H; Nakamura, M; Nishimura, T; Sawa, Y; Usui, C; Wakejima, T; Yoshida, K1
Hara, N; Ishida, Y; Miyata, K; Saiki, I; Seta, N; Tomino, M; Uchino, H; Yara, M1

Trials

5 trial(s) available for haloperidol and flunitrazepam

ArticleYear
Prophylaxis of alcohol withdrawal syndrome in alcohol-dependent patients admitted to the intensive care unit after tumour resection.
    British journal of anaesthesia, 1995, Volume: 75, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Chlormethiazole; Clonidine; Critical Care; Digestive System Neoplasms; Dopamine Antagonists; Drug Combinations; Ethanol; Female; Flunitrazepam; GABA Modulators; Haloperidol; Humans; Length of Stay; Male; Middle Aged; Postoperative Care; Postoperative Complications; Prospective Studies; Substance Withdrawal Syndrome

1995
Effects of various factors including the CYP2D6 genotype and coadministration of flunitrazepam on the steady-state plasma concentrations of bromperidol and its reduced metabolite.
    Psychopharmacology, 1998, Volume: 135, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Anti-Anxiety Agents; Antipsychotic Agents; Biotransformation; Cytochrome P-450 CYP2D6; Female; Flunitrazepam; Genotype; Half-Life; Haloperidol; Humans; Male; Middle Aged; Oxidation-Reduction; Schizophrenia; Sex Characteristics; Smoking

1998
Intramuscular flunitrazepam versus intramuscular haloperidol in the emergency treatment of aggressive psychotic behavior.
    The American journal of psychiatry, 1999, Volume: 156, Issue:1

    Topics: Acute Disease; Adult; Aggression; Antipsychotic Agents; Brief Psychiatric Rating Scale; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Emergency Medical Services; Female; Flunitrazepam; Haloperidol; Hospitalization; Humans; Injections, Intramuscular; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Treatment Outcome

1999
[Gamma-hydroxybutyrate for treatment of alcohol withdrawal syndrome in intensive care patients. A comparison between with two symptom-oriented therapeutic concepts].
    Der Anaesthesist, 1999, Volume: 48, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Alkalosis, Respiratory; Anti-Anxiety Agents; Antipsychotic Agents; Clonidine; Critical Care; Ethanol; Female; Flunitrazepam; Haloperidol; Humans; Hypernatremia; Male; Middle Aged; Prospective Studies; Sodium Oxybate; Substance Withdrawal Syndrome

1999
Alcohol withdrawal severity is decreased by symptom-orientated adjusted bolus therapy in the ICU.
    Intensive care medicine, 2003, Volume: 29, Issue:12

    Topics: Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Antipsychotic Agents; Clonidine; Decision Trees; Double-Blind Method; Female; Flunitrazepam; Haloperidol; Humans; Infusions, Intravenous; Intensive Care Units; Length of Stay; Male; Middle Aged; Severity of Illness Index; Sympatholytics

2003

Other Studies

20 other study(ies) available for haloperidol and flunitrazepam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of ferric nitrilotriacetate on rostral mesencephalic cells.
    Neurochemical research, 1991, Volume: 16, Issue:12

    Topics: Animals; Cells, Cultured; Clonazepam; Dopamine; Ferric Compounds; Flunitrazepam; Glutamate-Ammonia Ligase; Haloperidol; Mesencephalon; Mice; Neuroglia; Neurons; Nitrilotriacetic Acid; Spiperone

1991
Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons.
    Brain research, 1989, Aug-14, Volume: 494, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Flunitrazepam; Haloperidol; Hippocampus; In Vitro Techniques; Membrane Potentials; Phenytoin; Psychotropic Drugs; Rats; Sodium

1989
Effect of chronic haloperidol treatment on peripheral benzodiazepine binding sites in cerebral cortex of rats.
    Journal of neural transmission, 1988, Volume: 74, Issue:2

    Topics: Animals; Cerebral Cortex; Flunitrazepam; Haloperidol; Heart; Isoquinolines; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A

1988
3H-dopamine uptake and 3H-haloperidol binding in striatum after administration of methyl mercury to rats.
    Archives of toxicology, 1985, Volume: 57, Issue:4

    Topics: Animals; Cerebellum; Corpus Striatum; Dopamine; Flunitrazepam; Haloperidol; Hypothalamus; Male; Membranes; Methylmercury Compounds; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Serotonin

1985
Alterations in cerebral glutamic acid decarboxylase and 3H-flunitrazepam binding during continuous treatment of rats for up to 1 year with haloperidol, sulpiride or clozapine.
    Journal of neural transmission, 1987, Volume: 68, Issue:1-2

    Topics: Animals; Body Weight; Brain; Clozapine; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Haloperidol; Kinetics; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sulpiride; Time Factors

1987
Neuronal [3H]benzodiazepine binding and levels of GABA, glutamate, and taurine are normal in Huntington's disease cerebellum.
    Journal of neurochemistry, 1983, Volume: 41, Issue:5

    Topics: Amino Acids; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Humans; Huntington Disease; Middle Aged; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Taurine

1983
Effects of medazepam, flunitrazepam and bromocriptine on avoidance learning.
    Acta physiologica et pharmacologica Bulgarica, 1983, Volume: 9, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bromocriptine; Flunitrazepam; Haloperidol; Male; Medazepam; Rats; Rats, Inbred Strains

1983
[Changes in the number of benzodiazepine receptors in different parts of the brain of rats after neuroleptic withdrawal].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:10

    Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Flunitrazepam; Haloperidol; Humans; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance Withdrawal Syndrome; Sulpiride; Time Factors

1984
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Clozapine; Diffusion; Domperidone; Epithelium; Flunitrazepam; Haloperidol; Humans; Kidney; Kinetics; Loperamide; Male; Mice; Mice, Inbred Strains; Ondansetron; Phenytoin; Recombinant Proteins; Structure-Activity Relationship; Swine; Tissue Distribution; Transfection

1996
The association between intravenous haloperidol and prolonged QT interval.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Cohort Studies; Confidence Intervals; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Flunitrazepam; Haloperidol; Humans; Injections, Intravenous; Linear Models; Long QT Syndrome; Male; Middle Aged; Monitoring, Physiologic; Psychomotor Agitation; Statistics, Nonparametric; Tachycardia, Ventricular

2001
Two cases of deep vein thrombosis associated with antipsychotic drug use.
    Psychiatry and clinical neurosciences, 2004, Volume: 58, Issue:4

    Topics: Aged; Antipsychotic Agents; Chlorpromazine; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Overdose; Drug Therapy, Combination; Female; Flunitrazepam; Haloperidol; Humans; Middle Aged; Pulmonary Embolism; Risk; Schizophrenia; Venous Thrombosis

2004
[Comparison of emergency psychiatric services in Tokyo and Chiba prefecture].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:8

    Topics: Drug Utilization; Emergency Services, Psychiatric; Flunitrazepam; Haloperidol; Hospitalization; Hospitals, Psychiatric; Humans; Hypnotics and Sedatives; Japan; Mental Disorders; Practice Guidelines as Topic; Risk; Tokyo; Triage

2005
The effects of antipsychotic drugs on GABAA receptor binding depend on period of drug treatment and binding site examined.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding, Competitive; Flunitrazepam; GABA Agonists; GABA Modulators; Haloperidol; Humans; Long-Term Care; Male; Muscimol; Olanzapine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia

2007
Antipsychotic drug administration differentially affects [3H]muscimol and [3H]flunitrazepam GABA(A) receptor binding sites.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Densitometry; Flunitrazepam; Haloperidol; Hippocampus; Humans; Male; Muscimol; Olanzapine; Prefrontal Cortex; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Thalamus; Tissue Distribution; Tritium

2008
A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies: haloperidol versus flunitrazepam.
    Psychiatry research, 2010, Jun-30, Volume: 178, Issue:1

    Topics: Administration, Intravenous; Adult; Antipsychotic Agents; Drug Therapy, Combination; Electrocardiography; Female; Flunitrazepam; Haloperidol; Humans; Male; Mental Disorders; Middle Aged; Prospective Studies; Retrospective Studies; Treatment Outcome

2010
[Perioperative management of off-pump CABG for a 93-year-old man].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:10

    Topics: Aged, 80 and over; Anesthesia; Brain; Cerebrovascular Circulation; Consciousness Monitors; Coronary Artery Bypass, Off-Pump; Coronary Disease; Delirium; Flunitrazepam; Haloperidol; Humans; Intraoperative Care; Male; Monitoring, Intraoperative; Oxygen Consumption; Perioperative Care; Postoperative Complications; Treatment Outcome

2014