haloperidol has been researched along with dizocilpine maleate in 227 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (3.52) | 18.7374 |
| 1990's | 116 (51.10) | 18.2507 |
| 2000's | 62 (27.31) | 29.6817 |
| 2010's | 37 (16.30) | 24.3611 |
| 2020's | 4 (1.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Bergander, K; Fabian, J; Köhler, J; Schepmann, D; Wünsch, B | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Bourgeois, C; Christoph, T; Englberger, W; Galla, F; Galla, HJ; Hüwel, S; Kögel, B; Lehmkuhl, K; Schepmann, D; Soeberdt, M; Straßburger, W; Torres-Gómez, H; Werfel, E; Wünsch, B | 1 |
| Behrens, S; Gattaz, WF | 1 |
| Dall'Olio, R; Gandolfi, O; Rimondini, R | 1 |
| Kretschmer, BD; Schmidt, WJ; Volz, L; Volz, TL; Zadow, B | 1 |
| Hudzik, TJ | 1 |
| Joshi, RS; Marco, LA | 1 |
| Hoffman, DC | 1 |
| Kulkarni, SK; Verma, A | 2 |
| Ding, XZ; Mocchetti, I | 1 |
| McCann, DJ; Su, TP | 1 |
| Berger, P; Butman, M; Graham, SH; Koistinaho, J; Longo, FM; Noble, L; Sagar, SM; Sharp, FR; Wang, S | 1 |
| Calder, LD; Karler, R | 1 |
| Maj, J; Rogóz, Z; Skuza, G; Sowińska, H | 1 |
| deCosta, BR; Hardwick, WC; McMillan, DE; Rice, KC | 1 |
| Bakker, MH; Foster, AC | 1 |
| Cory-Slechta, DA; Widzowski, DV | 1 |
| Brent, PJ | 1 |
| Geyer, MA; Keith, VA; Mansbach, RS | 1 |
| Geyer, MA; Lehmann-Masten, VD | 1 |
| Maj, J; Rogóz, Z; Skuza, G | 1 |
| Lipton, P; Lobner, D | 1 |
| Calder, LD; Chaudhry, IA; Karler, R; Turkanis, SA | 2 |
| Bowen, WD; de Costa, B; Jacobson, AE; Kim, CH; Monn, JA; Reid, AA; Rice, KC; Rothman, RB; Thurkauf, A | 1 |
| Dragunow, M; Faull, RL; Jansen, K; Robertson, GS; Robertson, HA | 1 |
| Bischoff, C; Schmidt, WJ; Tiedtke, PI | 1 |
| Itoh, J; Kameyama, T; Nabeshima, T | 1 |
| Hauber, W; Schmidt, WJ | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Kesingland, AC; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| Albertson, TE; Derlet, RW; Rice, P | 1 |
| Ceci, A; French, ED | 1 |
| Culp, SG; De Souza, EB; Wolfe, SA | 1 |
| Carlsson, A; Carlsson, M | 1 |
| Bubser, M; Schmidt, WJ | 1 |
| Martin, GE; Ortegón, ME; Raffa, RB; Robisch, DM | 1 |
| Ahlemeyer, B; Krieglstein, J | 1 |
| Colpaert, FC; Kamenka, JM; Koek, W; Woods, JH | 1 |
| Gibbens, H; Headley, PM; Magnago, TS; Parsons, CG | 1 |
| Bowyer, JF | 1 |
| Ali, SF; Bowyer, JF; Holson, W; Newport, RR; Slikker, W | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Ogita, K; Yamada, K; Yoneda, Y | 1 |
| Green, AR; Hewitt, KE | 1 |
| Christensen, JR; Flory, GS; Miller, DW; Rebec, GV; White, IM | 1 |
| Bourin, M; Bradwejn, J; Harro, J; Kõks, S; Lang, A; Männistö, PT; Oreland, L; Soosaar, A; Vasar, E; Volke, V | 1 |
| Larson, AA; Sun, X | 4 |
| Behrens, S; Gattaz, WF; Schummer, B | 1 |
| Goldstein, M; Ogren, SO | 1 |
| Hasegawa, T; Kameyama, T; Katsumata, Y; Kinoshita, H; Nabeshima, T; Yamamoto, I | 1 |
| Cassella, JV; Donovan, H; Hoffman, DC | 1 |
| Maurice, T; Nabeshima, T; Parish, DW; Privat, A; Su, TP | 1 |
| Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E; Zuck, L | 1 |
| Schmidt, WJ; Zadow, B | 1 |
| Nencini, P; Valeri, P | 1 |
| Janowsky, A; Meshul, CK; Stallbaumer, RK; Taylor, B | 1 |
| Starr, JB; Werling, LL | 1 |
| Kovács, KJ; Larson, AA | 1 |
| Hasegawa, T; Kameyama, T; Kinoshita, H; Nabeshima, T; Yamamoto, I | 1 |
| Kameyama, T; Kobayashi, T; Ukai, M | 1 |
| Krug, D; Kunko, PM; Mueller, K; Saponjic, RM | 1 |
| Andersen, R; Hauber, W | 1 |
| Bowyer, JF; Broening, HW; Davies, DL; Holson, RR; Newport, GD; Schmued, L; Slikker, W | 1 |
| Amalric, M; Nieoullon, A; Ouagazzal, A | 1 |
| Shi, GG; Xu, SF | 1 |
| Beilharz, E; Dragunow, M; Gluckman, P; Hughes, P; Lawlor, P; MacGibbon, G; Singleton, K; Sirimanne, E; Young, D | 1 |
| Awere, S; Blackman, A; Leander, JD; Moore, NA | 1 |
| Lannes, B; Micheletti, G; Warter, JM; Zwiller, J | 1 |
| Castrén, E; da Penha Berzaghi, M; Lindholm, D; Thoenen, H | 1 |
| Höllt, V; Ziólkowska, B | 1 |
| Cohen, JM; Deutsch, SI; Hitri, A; Keuler, DJ; O'Connor, DA | 1 |
| Deutsch, SI; Hitri, A | 1 |
| Berger, P; Butman, M; Graham, SH; Koistinaho, J; Longo, FM; Sagar, SM; Sharp, FR; Wang, S | 1 |
| Deutsch, SI; Koetzner, L; Mastropaolo, J; Morn, CB; Rosse, RB; Sussman, DM | 1 |
| Chen, X; Hurlbert, M; Joseph, DB; Kumar, KN; Michaelis, EK; Michaelis, ML | 1 |
| Banks, DA; Flory, GS; Hooper, KC; Rebec, GV; Speciale, J; White, IM | 1 |
| Höllt, V; Ziółkowska, B | 1 |
| Hauber, W | 1 |
| Amalric, M; Ouagazzal, A | 1 |
| Olds, ME | 1 |
| Cabib, S; Caccia, S; Castellano, C; Felici, A; Mele, A; Oliverio, A | 1 |
| Hasegawa, M; Hasegawa, T; Nabeshima, T; Yamada, K | 1 |
| Angulo, JA; Ledoux, M; Lucas, LR; McEwen, BS; Noailles, PA; Villegas, M | 1 |
| Ammassari-Teule, M; Mele, A; Roullet, P | 1 |
| Hauber, W; Münkle, M | 1 |
| McCoy, L; Richfield, EK | 1 |
| Gallagher, MJ; Lynch, DR | 1 |
| Allen, C; Bunker, GL; Janowsky, A; Mason, JN; Meshul, CK | 1 |
| Berger, SP; Ho, LB; Reid, MS; Tolliver, BK | 1 |
| Gnegy, ME; Hewlett, GH; Pimputkar, G | 1 |
| Baker, I; Masserano, JM; Natsukari, N; Wyatt, RJ | 1 |
| McAllister, KH | 1 |
| Junien, JL; Maurice, T; Privat, A | 1 |
| Duman, RS; Morinobu, S; Strausbaugh, H; Terwilliger, R | 1 |
| Maurice, T; Privat, A | 1 |
| Vanover, KE | 1 |
| Kaur, S; Ozer, H; Starr, M | 1 |
| Löscher, W; Richter, A | 1 |
| Curzon, P; Decker, MW | 1 |
| Gallagher, MJ; Huang, H; Lynch, DR | 1 |
| Jentsch, JD; Roth, RH; Taylor, JR | 1 |
| Baca, SM; Egan, MF; Hamid, EH; Hyde, TM | 1 |
| Campbell, IG; Feinberg, I | 1 |
| Aizenman, E; Brimecombe, JC; Gallagher, MJ; Lynch, DR | 1 |
| Fuwa, T; Miwa, H; Mizuno, Y; Nishi, K | 1 |
| Kulkarni, SK; Ninan, I | 1 |
| Argiolas, A; Melis, MR; Spano, MS; Succu, S | 1 |
| Cardwell, GP; Hicks, CA; O'Neill, MF; O'Neill, MJ; Parameswaran, T; Shaw, G | 1 |
| Konieczny, J; Lorenc-Koci, E; Ossowska, K; Wolfarth, S | 1 |
| Bittigau, P; Bosch, F; Dikranian, K; Ikonomidou, C; Miksa, M; Olney, JW; Stefovska, V; Tenkova, TI; Turski, L; Vöckler, J | 1 |
| de Groat, WC; Namiki, M; Yokoyama, O; Yoshiyama, M | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Nilsson, M; Sorensen, SM; Waters, N; Waters, S | 1 |
| Ahmed, MS; Enna, SJ; Mather, A | 1 |
| Katayama, S; Kohno, H; Ohkubo, Y; Ohuchi, Y | 1 |
| de Souza, IE; Meredith, GE | 1 |
| Nowak, G; Ossowska, K; Pietraszek, M; Wardas, J; Wolfarth, S | 1 |
| Caron, MG; Gainetdinov, RR; Koller, BH; Mohn, AR | 1 |
| Kretschmer, BD; Schmidt, WJ; Tzschentke, TM | 1 |
| Chartoff, EH; Dorsa, DM; Ward, RP | 1 |
| Feifel, D; Priebe, K | 1 |
| Baca, SM; Hyde, TM; Jaskiw, GE; Kleinman, JE; Murray, AM; Spurney, CF | 1 |
| Bradley, RJ; Dwyer, DS; Liu, Y | 1 |
| Barczak, A; Carlson, RR; Coyle, JT; Heckers, S; Huganir, RL; Kang, S; Konradi, C; Leveque, JC; Li, XM; Macías, W; Rajadhyaksha, A | 1 |
| Fujimura, M; Hashimoto, K; Yamagami, K | 1 |
| Fendt, M; Koch, M; Schwienbacher, I | 1 |
| Gmiro, VE; Gorbunova, LV; Lukomskaia, NIa; Rukoiatkina, NI | 1 |
| Bast, T; Feldon, J; White, IM; Zhang, W | 1 |
| Flumerfelt, BA; Hussain, N; Rajakumar, N | 2 |
| Castrén, E; Korpi, ER; Lakso, M; Lindén, AM; Storvik, M; Väsänen, J; Wong, G | 1 |
| Corsini, G; Fumagalli, F; Gennarelli, M; Maggio, R; Molteni, R; Racagni, G; Riva, M; Roceri, M | 1 |
| Gallagher, MJ; Guttmann, RP; Kurapathi, S; Lynch, DR; Mutel, V; Seifert, KM; Shim, SS | 1 |
| Feifel, D; Priebe, K; Shilling, PD | 1 |
| Carlsson, A; Carlsson, ML; Nilsson, M; Waters, N; Waters, S | 1 |
| Breese, GR; Knapp, DJ; Moy, SS | 1 |
| Franks, NP; Ma, D; Maze, M; Wilhelm, S | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Minami, M; Nishikawa, H; Satoh, M; Taguchi, R | 1 |
| Gaisler-Salomon, I; Weiner, I | 1 |
| Bedogni, F; Fossati, C; Fumagalli, F; Gennarelli, M; Molteni, R; Racagni, G; Riva, MA; Roceri, M; Santero, R | 1 |
| Gmiro, VE; Gorbunova, LV; Lukomskaya, NY; Rukoyatkina, NI | 1 |
| Conway, MW; Heron-Maxwell, C; Monn, JA; O'Neill, MF; Ornstein, P | 1 |
| Lee, J; Rajakumar, N | 1 |
| France, CP; Koek, W; Sevak, RJ | 2 |
| Halim, ND; Lipska, BK; McClintock, BW; Weickert, CS; Weinberger, DR | 1 |
| Hashimoto, K; Hattori, K; Iyo, M; Yanahashi, S; Yuasa, S | 1 |
| Engel, JA; Klamer, D; Pålsson, E; Revesz, A; Svensson, L | 1 |
| Carlsson, A; Carlsson, ML; Gullme, M; Markinhuhta, KR; Nilsson, M; Pettersson, F; Sonesson, C | 1 |
| Dall'Igna, OP; de Oliveira, RV; Fett, P; Gomes, MW; Lara, DR; Mantese, CE; Schuh, J; Souza, DO; Tort, AB | 1 |
| Akbarian, S; Ferris, C; Guo, Y; Konradi, C; Li, J; Schmidt, TW; Schroeder, FA; Youngs, RM | 1 |
| Aru, GN; Bortolato, M; Casti, A; Fà, M; Frau, R; Gessa, GL; Luckey, GC; Mereu, G; Orrù, M; Salis, P | 1 |
| Bubeníková, V; Horácek, J; Höschl, C; Kozený, J; Pálenícek, T; Platilová, V; Závesická, L | 1 |
| Brotchie, JM; Fox, SH; Gomez-Ramirez, J; Johnston, TH; Lee, J | 1 |
| Chartoff, EH; Heusner, CL; Palmiter, RD | 1 |
| Carlsson, A; Carlsson, ML; Markinhuhta, KR; Rung, JP | 1 |
| Aru, GN; Bortolato, M; Fà, M; Frau, R; Gessa, GL; Manunta, M; Mereu, G; Orrù, M; Puddu, M | 1 |
| Dall'Igna, OP; Lara, DR; Souza, DO; Tort, AB | 1 |
| Bennett, S; Gronier, B | 2 |
| Ahmed, MM; Arif, M; Chikuma, T; Hoshino, H; Kato, T; Kumabe, Y | 1 |
| Burne, TH; Eyles, DW; Kesby, JP; McGrath, JJ | 1 |
| Homayoun, H; Moghaddam, B | 1 |
| Barbakadze, T; Mikeladze, DG; Natsvlishvili, N; Zhuravliova, E | 1 |
| Ahmed, MM; Arif, M; Chikuma, T; Kato, T; Yoshida, S | 1 |
| Blennow, K; Davidsson, P; Ljung, E; Martin, P; Paulson, L | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Babot, Z; López-Gil, X; Suñol, C | 1 |
| Anderson, GT; Barido, R; Bonhaus, DW; Brann, MR; Brunmark, P; Davis, RE; Dyssegaard, A; Gardell, LR; Hacksell, U; Johnson, RW; Pounds, L; Tabatabaei, A; Vanover, KE; Veinbergs, I | 1 |
| Bender, A; Braun, I; Genius, J; Grunze, H; Möller, HJ; Rujescu, D | 1 |
| Chaki, S; Hashimoto, K; Karasawa, J | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Bubenikova-Valesova, V; Bures, J; Stuchlik, A; Svoboda, J; Vales, K | 1 |
| Gmiro, VE; Serdyuk, SE | 1 |
| Agovic, MS; Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E | 1 |
| Belknap, J; Darakjian, P; Hitzemann, R; Malmanger, B; McWeeney, S | 1 |
| de Moura Linck, V; Elisabetsky, E; Goerck, GC; Herrmann, AP; Iwu, MM; Leal, MB; Okunji, CO | 1 |
| Heilig, M; Holmes, A; Karlsson, RM; Tanaka, K | 1 |
| Brown, AS; Butler, PD; Keegan, D; Palmer, AA; Rotrosen, J; Siska, LD; Susser, E | 1 |
| Arad, M; Barak, S; Black, MD; Boulay, D; De Levie, A; Griebel, G; Pichat, P; Varty, GB; Weiner, I | 1 |
| Chai, YG; Choi, J; Choi, MR; Kim, D; Kim, DJ; Kim, SH; Lee, JS; Park, YC; Roh, K; Roh, S; Yang, BH | 1 |
| Comery, TA; Graf, R; Grauer, SM; Huselton, C; Liu, Z; Logue, SF; Marquis, KL; Navarra, R; Rosenzweig-Lipson, S; Stack, G; Sung, A | 1 |
| Nishikawa, T; Takebayashi, H; Umino, A; Yamamoto, N | 1 |
| Carlezon, WA; Paine, TA | 1 |
| Chaki, S; Kaku, A; Shimazaki, T | 1 |
| Arrang, JM; Burban, A; Dumoulin, D; Frances, H; Le Pen, G; Rose, C; Sadakhom, C | 1 |
| Lin, PJ; Liu, YP; Tung, CS; Wan, FJ | 1 |
| Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P | 1 |
| Bubenikova-Valesova, V; Horacek, J; Sumiyoshi, T; Svoboda, J | 1 |
| Abekawa, T; Ito, K; Koyama, T; Nakagawa, S; Nakato, Y | 1 |
| Kulak, A; Riedinger, K; Schmidt, WJ; von Ameln-Mayerhofer, A | 1 |
| Bonan, CD; da Luz Oliveira, R; Rosemberg, DB; Savio, LE; Scherer, EB; Schmitz, F; Seibt, KJ; Wyse, AT | 1 |
| Bilge, U; Erol, K | 1 |
| Akhtar, M; Khanam, R; Mahmood, D; Pillai, KK | 1 |
| Benninghoff, J; Braun, I; Genius, J; Giegling, I; Hartmann, A; Möller, HJ; Reuter, N; Rujescu, D | 1 |
| Basar, K; Ertugrul, A; Ozdemir, H; Saka, E | 1 |
| Benninghoff, J; Dölzer, AL; Geiger, J; Genius, J; Giegling, I; Hartmann, AM; Möller, HJ; Rujescu, D | 1 |
| Fijał, K; Nikiforuk, A; Popik, P | 1 |
| Callahan, PM; Tehim, A; Terry, AV | 1 |
| Barbosa-Silva, RC; Medeiros, P; Melo-Thomas, L; Tonelli, LC; Viana, MB | 1 |
| Irifune, M; Kanematsu, T; Kikuchi, N; Morioka, N; Morita, K; Nakata, Y; Sakai, N; Shimizu, Y; Yoshida, K | 1 |
| Fang, Y; Xu, L; Zhang, C | 1 |
| Chaki, S; Hiyoshi, T; Kambe, D; Karasawa, J | 1 |
| Chaki, S; Hikichi, H; Kaku, A; Kambe, D; Karasawa, J; Kawaura, K; Kinoshita, K; Koike, H | 1 |
| Deng, CM; Gao, YY; Li, Y; Mu, YL; Ou, BC; So, JH; Tan, ZB; Tang, M; Wang, YQ; Zhang, LQ; Zhu, ZR | 1 |
| Habata, Y; Imaichi, S; Komatsu, H; Maruyama, M; Mori, M; Sakuma, K | 1 |
| Burke, DA; Hall, BJ; Larrauri, JA; Levin, ED | 1 |
| Hiekkalinna, T; Kuja-Panula, J; Kulesskaya, N; Lauri, SE; Liuhanen, J; Paunio, T; Peltola, MA; Piepponen, P; Rauvala, H; Suvisaari, J; Taira, T; Võikar, V | 1 |
| Hunt, MJ; Kasicki, S; Olszewski, M; Piasecka, J; Whittington, MA | 1 |
| Cao, WY; Dai, RP; Hu, ZL; Huang, FL; Kang, WJ; Li, CQ; Li, F; Wang, HT; Zhang, J; Zhang, JY; Zhong, XL; Zhou, XF | 1 |
| Hudson, MR; Jones, NC; O'Brien, TJ; Rind, G | 1 |
| Liu, D; Mao, S; Peng, Y; Qin, X; Zhang, R; Zhou, X | 1 |
| Castro, E; Ferrer, I; Pinacho, R; Prades, R; Ramos, B; Tarragó, T; Vila, E | 1 |
| Dehpour, AR; Imran Khan, M; Norouzi-Javidan, A; Ostadhadi, S | 1 |
| Aznar, S; Blázquez, G; Cañete, T; Corda, MG; Fernández-Teruel, A; Gerbolés, C; Giorgi, O; González-Maeso, J; Oliveras, I; Piludu, MA; Río-Alamos, C; Sampedro-Viana, D; Sánchez-González, A; Tobeña, A | 1 |
| Iha, HA; Inada, A; Ohno, Y; Shimizu, S; Sogabe, S; Yamanaka, M; Yanagisako, R | 1 |
| He, GF; He, GZ; Lei, K; Li, J; Li, XP; Liu, D; Liu, YN; Ren, XH; Zhang, CL | 1 |
| Ishihara, T; Kitamura, N; Matsumoto, Y; Murakami, S; Okamoto, M; Suemitsu, S; Takahashi, Y; Ueno, H; Wani, K | 1 |
| Balenovic, I; Blagaic, AB; Cilic, M; Drmic, D; Filipcic, I; Ilic, S; Kokot, A; Seiwerth, S; Sikiric, P; Strbe, S; Tvrdeic, A; Vukojevic, J; Zemba Cilic, A; Zemba, M; Zoricic, Z | 1 |
| Hamilton, J; Richardson, B; Thanos, P; Waldman, L | 1 |
| Buyukuysal, RL; Gul, Z; Gursoy, M | 1 |
1 review(s) available for haloperidol and dizocilpine maleate
| Article | Year |
|---|---|
Integrative role for serotonergic and glutamatergic receptor mechanisms in the action of NMDA antagonists: potential relationships to antipsychotic drug actions on NMDA antagonist responsiveness.
Topics: Animals; Antipsychotic Agents; Behavior; Behavior, Animal; Brain; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Haloperidol; Humans; Phencyclidine; Psychoses, Substance-Induced; Receptors, Dopamine; Receptors, Glutamate; Receptors, Serotonin; Schizophrenia | 2002 |
226 other study(ies) available for haloperidol and dizocilpine maleate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Enantiomerically pure 1,3-dioxanes as highly selective NMDA and σ₁ receptor ligands.
Topics: Animals; Benzylamines; Binding Sites; Binding, Competitive; Cerebral Cortex; Dioxanes; Ethylamines; Guinea Pigs; Ligands; Phencyclidine; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stereoisomerism; Swine | 2012 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Blood-Brain Barrier; Brain; Endothelial Cells; Guinea Pigs; HEK293 Cells; Humans; Liver; Male; Mice; Models, Molecular; Pain Measurement; Permeability; Pyrrolidines; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship | 2014 |
MK-801 induced stereotypies in rats are decreased by haloperidol and increased by diazepam.
Topics: Animals; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Rats; Rats, Wistar; Stereotyped Behavior | 1992 |
The modulation of dopaminergic transmission in the striatum by MK-801 is independent of presynaptic mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Haloperidol; Male; Methamphetamine; Motor Activity; Nomifensine; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1992 |
The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Catalepsy; Cycloserine; Dizocilpine Maleate; Haloperidol; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
A ketamine-induced rat model of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Haloperidol; Ketamine; Metoclopramide; Pharynx; Rats; Rats, Inbred Strains; Stereotyped Behavior; Tongue | 1992 |
Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Salicylamides; Stereotyped Behavior | 1992 |
D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats.
Topics: Animals; Benzazepines; Catalepsy; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Drug Interactions; Female; Haloperidol; Male; Perphenazine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1992 |
Regulation of cholecystokinin mRNA content in rat striatum: a glutamatergic hypothesis.
Topics: Animals; Cholecystokinin; Corpus Striatum; Dizocilpine Maleate; DNA Probes; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; RNA Probes | 1992 |
Tris inhibits (+)-[3H]SKF-10,047 binding to sigma receptors.
Topics: Animals; Dizocilpine Maleate; Haloperidol; Liver; Male; Phenazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stereoisomerism; Tritium; Tromethamine | 1992 |
Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine.
Topics: Amygdala; Animals; Base Sequence; Carbazoles; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Gene Expression; Haloperidol; Heat-Shock Proteins; Humans; Immunohistochemistry; Ketamine; Kinetics; Microscopy, Electron; Molecular Sequence Data; Neurons; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Phencyclidine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reference Values; Restriction Mapping; RNA, Messenger | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Effects of MK-801 and antidepressant drugs in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Dizocilpine Maleate; Haloperidol; Imipramine; Male; Mianserin; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Swimming | 1992 |
Effects of drugs that bind to PCP and sigma receptors on punished responding.
Topics: Animals; Buspirone; Dizocilpine Maleate; Haloperidol; Learning; Male; Pentobarbital; Phenazocine; Phencyclidine; Punishment; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1991 |
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diazepam; Dizocilpine Maleate; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; Injections; Male; Nerve Degeneration; Pipecolic Acids; Piperazines; Piperidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Cocaine; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Dopamine Agents; Drug Synergism; Ergolines; Generalization, Psychological; Haloperidol; Lead; Male; Morphine; N-Methylaspartate; Pentobarbital; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle.
Topics: Animals; Arousal; Attention; Brain; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Loudness Perception; Male; Neural Inhibition; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Touch | 1991 |
Spatial and temporal patterning distinguishes the locomotor activating effects of dizocilpine and phencyclidine in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Exploratory Behavior; Haloperidol; Male; Motor Activity; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains | 1991 |
Antidepressant drugs increase the locomotor hyperactivity induced by MK-801 in rats.
Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Dizocilpine Maleate; Drug Interactions; Haloperidol; Imipramine; Male; Mianserin; Motor Activity; Prazosin; Rats; Rats, Inbred Strains | 1991 |
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate; Glutamates; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Ketamine; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1990 |
Amphetamine behavioral sensitization and the excitatory amino acids.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Cyproheptadine; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Ketamine; Male; Mice; Neuroeffector Junction; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1990 |
Wash-resistant inhibition of phencyclidine- and haloperidol-sensitive sigma receptor sites in guinea pig brain by putative affinity ligands: determination of selectivity.
Topics: Affinity Labels; Animals; Brain; Cerebellum; Dizocilpine Maleate; Guinea Pigs; Haloperidol; Kinetics; Ligands; Membranes; Phencyclidine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
D2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons.
Topics: Animals; Benzamides; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Guanidines; Haloperidol; Male; N-Methylaspartate; Neurons; Oncogene Proteins v-fos; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma | 1990 |
MK-801-induced stereotypy and its antagonism by neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzazepines; Dibenzocycloheptenes; Dizocilpine Maleate; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereotyped Behavior | 1990 |
Utility of an elevated plus-maze for dissociation of amnesic and behavioral effects of drugs in mice.
Topics: Amnesia; Animals; Behavior, Animal; Butylscopolammonium Bromide; Diazepam; Dizocilpine Maleate; Haloperidol; Male; Methamphetamine; Mice; Mice, Inbred Strains; Psychopharmacology; Scopolamine | 1991 |
The NMDA antagonist dizocilpine (MK-801) reverses haloperidol-induced movement initiation deficits.
Topics: Animals; Appetitive Behavior; Arousal; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Rats; Rats, Inbred Strains; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1990 |
Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.
Topics: Animals; Aspartic Acid; Baclofen; Bromocriptine; Catalepsy; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Haloperidol; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Scopolamine | 1990 |
Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).
Topics: Animals; Aspartic Acid; Binding, Competitive; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1990 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Haloperidol; Lethal Dose 50; Male; Methamphetamine; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Seizures | 1990 |
Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons.
Topics: Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Haloperidol; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1990 |
Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary.
Topics: Adrenal Glands; Animals; Autoradiography; Brain Chemistry; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Haloperidol; Hypophysectomy; Male; Ovary; Phencyclidine; Piperidines; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Testis; Tissue Distribution | 1989 |
The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice.
Topics: alpha-Methyltyrosine; Animals; Biogenic Monoamines; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reserpine | 1989 |
Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats.
Topics: Animals; Catalepsy; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
In vivo demonstration of the enhancement of MK-801 by L-glutamate.
Topics: Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutamates; Glutamic Acid; Haloperidol; Kinetics; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1989 |
Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801.
Topics: Amphetamine; Animals; Anticonvulsants; Cocaine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Haloperidol; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1989 |
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Flunarizine; Haloperidol; Imipramine; Ketamine; Lidocaine; Nafronyl; Neurons; Pyrithioxin; Telencephalon | 1989 |
The phencyclidine (PCP) analog N-[1-(2-benzo(B)thiophenyl) cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801.
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dextroamphetamine; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Haloperidol; Ketamine; Methylphenidate; Mice; Phencyclidine; Rats; Seizures; Structure-Activity Relationship | 1989 |
At which 'sigma' site are the spinal actions of ketamine mediated?
Topics: Action Potentials; Animals; Binding, Competitive; Dibenzocycloheptenes; Dizocilpine Maleate; Haloperidol; Ketamine; Male; Motor Neurons; Nociceptors; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1988 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
N-Methyl-D-aspartate receptor participation in Parkinson's disease, a neurodegenerative disorder.
Topics: Animals; Antiparkinson Agents; Apomorphine; Benzazepines; Catalepsy; Dizocilpine Maleate; Haloperidol; Ketamine; Mice; Neuroprotective Agents; Parkinson Disease, Secondary; Perphenazine; Rats; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
Low environmental temperatures or pharmacologic agents that produce hyperthermia decrease methamphetamine neurotoxicity in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cold Temperature; Corpus Striatum; Dizocilpine Maleate; Dopamine; Haloperidol; Homovanillic Acid; Hypothermia; Hypothermia, Induced; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neuroprotective Agents; Neurotoxins; Pentobarbital; Phenobarbital | 1995 |
Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Drug Tolerance; Haloperidol; Isoxazoles; Male; Methamphetamine; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, Serotonin; Risperidone; Ritanserin | 1995 |
Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats.
Topics: Animals; Chlormethiazole; Dizocilpine Maleate; Haloperidol; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin | 1994 |
Amphetamine, cocaine, and dizocilpine enhance performance on a lever-release, conditioned avoidance response task in rats.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1995 |
Role of N-methyl-D-aspartic acid and cholecystokinin receptors in apomorphine-induced aggressive behaviour in rats.
Topics: Aggression; Animals; Apomorphine; Benzodiazepinones; Brain Chemistry; Clozapine; Devazepide; Dizocilpine Maleate; Haloperidol; Male; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cholecystokinin; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1995 |
The amino-terminus of substance P mimics and MK-801 attenuates the effects of capsaicin on nociception and kainic acid-induced behavior in the mouse.
Topics: Analysis of Variance; Animals; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; Pain; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Substance P | 1993 |
MK-801 inhibits the effects of capsaicin in the adult mouse by an action involving phencyclidine (PCP) sites not linked to NMDA activity.
Topics: Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; Pain Measurement; Pain Threshold; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Substance P | 1993 |
Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: involvement of phencyclidine (PCP) sites not linked to N-methyl-D-aspartate (NMDA) activity.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Synergism; Guanidines; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord; Substance P; Up-Regulation | 1993 |
Effects of zotepine, haloperidol and clozapine on MK-801-induced stereotypy and locomotion in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Rats; Rats, Wistar; Stereotyped Behavior | 1994 |
Phencyclidine- and dizocilpine-induced hyperlocomotion are differentially mediated.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Ergolines; Haloperidol; Male; Motor Activity; Phencyclidine; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remoxipride; Salicylamides | 1994 |
Effect of dizocilpine (MK-801) on the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: Acetylcholine; Animals; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dronabinol; Haloperidol; Male; Mice; Oxotremorine; Parkinson Disease; Receptors, N-Methyl-D-Aspartate | 1994 |
The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801.
Topics: Acoustic Stimulation; Animals; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1993 |
PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Cholinergic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Morpholines; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 1994 |
Anti-glutamatergic effects of clozapine.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Humans; Membrane Potentials; Rats; Vibrissae | 1993 |
The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Drug Interactions; Ergolines; Haloperidol; Levodopa; Male; Pilot Projects; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
The role of opioid mechanisms in the anorectic effects of stimulants: U50,488H enhances amphetamine inhibition of free feeding in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamine; Animals; Appetite Depressants; Central Nervous System Stimulants; Diuresis; Dizocilpine Maleate; Dopamine; Drinking; Drug Synergism; Eating; Endorphins; Haloperidol; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Urodynamics | 1994 |
Haloperidol-induced morphological changes in striatum are associated with glutamate synapses.
Topics: Animals; Benzazepines; Dizocilpine Maleate; Glutamic Acid; Haloperidol; Immunohistochemistry; Injections; Male; Microscopy, Electron; Neostriatum; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Sigma-receptor regulation of [3H]arachidonic acid release from rat neonatal cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Arachidonic Acid; Binding, Competitive; Cell Membrane; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Haloperidol; Kinetics; Melitten; N-Methylaspartate; Neurons; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium | 1994 |
Density of NMDA-coupled and uncoupled 1-[1-(2-[3H]thienyl) cyclohexyl]piperidine recognition sites in the brain and spinal cord: differential effects of NMDA agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Dizocilpine Maleate; Glutamic Acid; Glycine; Haloperidol; Male; Mice; N-Methylaspartate; Phencyclidine; Spinal Cord; Tritium | 1994 |
Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amantadine; Amino Acids; Animals; Anticonvulsants; Catalepsy; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Ergolines; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Quinpirole; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1994 |
Effects of several amnesic drugs on the habituation of exploratory activity in mice as indexed by horizontal and vertical activities.
Topics: Amnesia; Animals; Behavior, Animal; Butylscopolammonium Bromide; Cycloheximide; Diazepam; Dizocilpine Maleate; Exploratory Behavior; Habituation, Psychophysiologic; Haloperidol; Male; Memory; Mice; Mice, Inbred Strains; Pirenzepine; Scopolamine | 1994 |
The effects of haloperidol, scopolamine, and MK-801 on amphetamine-induced increases in ascorbic and uric acid as determined by voltammetry in vivo.
Topics: Amphetamine; Animals; Ascorbic Acid; Caudate Nucleus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes; Haloperidol; Male; Rats; Rats, Wistar; Scopolamine; Uric Acid | 1994 |
MK-801 and phencyclidine act at phencyclidine sites that are not linked to N-methyl-D-aspartate activity to inhibit behavioral sensitization to kainate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; N-Methylaspartate; Nociceptors; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord | 1993 |
The non-NMDA glutamate receptor antagonist GYKI 52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Further studies of the role of hyperthermia in methamphetamine neurotoxicity.
Topics: Animals; Binding Sites; Corpus Striatum; Diazepam; Dizocilpine Maleate; Dopamine; Glial Fibrillary Acidic Protein; Haloperidol; Hyperthermia, Induced; Hypothermia, Induced; Immunohistochemistry; Interleukin-1; Male; Methamphetamine; Nervous System; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1994 |
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synapses | 1994 |
Effect of phencyclidine on contraction of porcine coronary vessel strips.
Topics: Animals; Biological Assay; Coronary Vessels; Dextromethorphan; Dizocilpine Maleate; Haloperidol; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Phenazocine; Phencyclidine; Receptors, Phencyclidine; Receptors, sigma; Swine | 1993 |
Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?
Topics: Animals; Apoptosis; Brain Ischemia; Dizocilpine Maleate; Genes, fos; Genes, jun; Haloperidol; Hypoxia, Brain; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Transcription, Genetic | 1993 |
NMDA receptor antagonists inhibit catalepsy induced by either dopamine D1 or D2 receptor antagonists.
Topics: Animals; Benzamides; Benzazepines; Catalepsy; Chlordiazepoxide; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Haloperidol; Isoquinolines; Male; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 1993 |
Evidence for NMDA/D2 receptor-receptor interactions in the rat striatum.
Topics: Animals; Apomorphine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Globus Pallidus; Haloperidol; Ketamine; Male; Neural Pathways; Rats; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei | 1993 |
Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Haloperidol; In Situ Hybridization; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution | 1993 |
The NMDA receptor antagonist MK-801 markedly reduces the induction of c-fos gene by haloperidol in the mouse striatum.
Topics: Animals; Blotting, Northern; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Haloperidol; In Situ Hybridization; Kinetics; Male; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; RNA Probes; RNA, Messenger | 1993 |
Differentiation between MK-801- and apomorphine-induced stereotyped behaviors in mice.
Topics: Analysis of Variance; Animals; Apomorphine; Clozapine; Dizocilpine Maleate; Haloperidol; Male; Mice; Stereotyped Behavior; Time Factors | 1993 |
Measurement of an explosive behavior in the mouse, induced by MK-801, a PCP analogue.
Topics: Analysis of Variance; Animals; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Receptors, Phencyclidine; Time Factors | 1993 |
Heat shock proteins used to show that haloperidol prevents neuronal injury produced by ketamine, MK801, and phencyclidine.
Topics: Animals; Biomarkers; Cell Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gyrus Cinguli; Haloperidol; Heat-Shock Proteins; Ketamine; Neurons; Neurotoxins; Phencyclidine; Rats | 1993 |
Computerized measurement of MK-801-elicited popping and hyperactivity in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred Strains | 1995 |
Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex.
Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Haloperidol; Illicit Drugs; Kinetics; Male; Membrane Proteins; N-Methylaspartate; Phencyclidine; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Spermidine; Synaptic Membranes; Tritium | 1996 |
Phencyclidine-induced increases in striatal neuron firing in behaving rats: reversal by haloperidol and clozapine.
Topics: Animals; Behavior, Animal; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Locomotion; Male; Membrane Potentials; Neurons; Phencyclidine; Rats; Rats, Sprague-Dawley | 1995 |
Fos is not involved in the regulation of the proenkephalin gene by haloperidol in the mouse striatum.
Topics: Analysis of Variance; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Mice; Mice, Inbred Strains; Protein Precursors | 1995 |
Impairments of movement initiation and execution induced by a blockade of dopamine D1 or D2 receptors are reversed by a blockade of N-methyl-D-aspartate receptors.
Topics: Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Locomotion; Male; Motor Activity; Movement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 1996 |
Competitive NMDA receptor antagonists do not produce locomotor hyperactivity by a dopamine-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Hyperkinesis; Injections; Male; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 1995 |
Dopaminergic basis for the facilitation of brain stimulation reward by the NMDA receptor antagonist, MK-801.
Topics: Amphetamine; Analysis of Variance; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Haloperidol; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Self Stimulation | 1996 |
Dopamine-N-methyl-D-aspartate interactions in the modulation of locomotor activity and memory consolidation in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Avoidance Learning; Benzazepines; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sulpiride | 1996 |
Role of dopaminergic neuronal system in dizocilpine-induced acetylcholine release in the rat brain.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Haloperidol; Hippocampus; Male; Methyltyrosines; Neostriatum; Parietal Lobe; Rats; Rats, Wistar; Receptors, Dopamine D1 | 1996 |
Acute treatment with the N-methyl-D-aspartate receptor antagonist MK-801: effect of concurrent administration of haloperidol or scopolamine on preproenkephalin mRNA levels of the striatum and nucleus accumbens of the rat brain.
Topics: Animals; Base Sequence; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Haloperidol; In Situ Hybridization; Male; Molecular Sequence Data; Muscarinic Antagonists; Neostriatum; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Scopolamine | 1996 |
Involvement of glutamatergic and dopaminergic systems in the reactivity of mice to spatial and non-spatial change.
Topics: Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; Mice; Motor Activity; Spatial Behavior | 1996 |
The adenosine receptor antagonist theophylline induces a monoamine-dependent increase of the anticataleptic effects of NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Theophylline | 1996 |
Chronic antipsychotic treatment alters glycine-stimulated NMDA receptor binding in rat brain.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain Chemistry; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Haloperidol; Male; Pimozide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Time Factors; Tritium | 1996 |
Inhibition of N-methyl-D-aspartate receptors by haloperidol: developmental and pharmacological characterization in native and recombinant receptors.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Haloperidol; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Recombinant Proteins; Spermidine | 1996 |
Effects of subchronic clozapine and haloperidol on striatal glutamatergic synapses.
Topics: Alternative Splicing; Animals; Base Sequence; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Genetic Variation; Glutamic Acid; Haloperidol; In Situ Hybridization; Ion Channels; Macromolecular Substances; Male; Microscopy, Immunoelectron; Nerve Endings; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA Probes; Synapses | 1996 |
Evidence for dissociable mechanisms of amphetamine- and stress-induced behavioral sensitization: effects of MK-801 and haloperidol pretreatment.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dizocilpine Maleate; Haloperidol; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Physiological | 1996 |
Haloperidol and MK-801 block increases in striatal calmodulin resulting from repeated amphetamine treatment.
Topics: Amphetamine; Animals; Calmodulin; Calmodulin-Binding Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Haloperidol; Rats; Rats, Sprague-Dawley | 1996 |
Chronic cocaine administration increases tyrosine hydroxylase activity in the ventral tegmental area through glutaminergic- and dopaminergic D2-receptor mechanisms.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glutamate; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 1996 |
The competitive NMDA receptor antagonist SDZ 220-581 reverses haloperidol-induced catalepsy in rats.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Biphenyl Compounds; Catalepsy; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Male; Molecular Structure; Neuroprotective Agents; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Structure-Activity Relationship | 1996 |
Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Injections, Subcutaneous; Learning Disabilities; Ligands; Male; Memory Disorders; Mice; Pyrimidines; Receptors, sigma | 1997 |
Regulation of c-Fos and NGF1-A by antidepressant treatments.
Topics: Adrenergic Antagonists; Animals; Antidepressive Agents; Benzazepines; Blotting, Western; Dizocilpine Maleate; DNA-Binding Proteins; Dopamine Antagonists; Early Growth Response Protein 1; Electroshock; Excitatory Amino Acid Antagonists; Frontal Lobe; Genes, fos; Genes, Immediate-Early; Haloperidol; Imipramine; Immediate-Early Proteins; Ketanserin; Male; Prazosin; Propranolol; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Transcription Factors; Transcription, Genetic; Tranylcypromine | 1997 |
SA4503, a novel cognitive enhancer with sigma1 receptor agonist properties, facilitates NMDA receptor-dependent learning in mice.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Cognition; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Maze Learning; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Progesterone; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spatial Behavior | 1997 |
Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dioxoles; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Locomotion; Male; Mice; Piperidines; Receptors, AMPA | 1997 |
MK 801 reverses haloperidol-induced catalepsy from both striatal and extrastriatal sites in the rat brain.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Globus Pallidus; Haloperidol; Male; Muscimol; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thalamus | 1997 |
MK-801 potentiates antidystonic effects of clozapine but not of haloperidol in mutant dystonic hamsters.
Topics: Animals; Anti-Dyskinesia Agents; Catalepsy; Clozapine; Cricetinae; Dizocilpine Maleate; Drug Synergism; Dystonia; Female; Haloperidol; Male; Mutation; Neuroprotective Agents | 1997 |
Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.
Topics: Acoustic Stimulation; Animals; Apomorphine; Clozapine; Dextroamphetamine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred Strains; Phencyclidine; Piperidines; Rats; Receptors, sigma; Reflex, Startle; Species Specificity | 1998 |
Modulation of the N-methyl-D-aspartate receptor by haloperidol: NR2B-specific interactions.
Topics: Amino Acid Sequence; Binding, Competitive; Chimera; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Mutagenesis, Site-Directed; Piperidines; Receptors, N-Methyl-D-Aspartate; Spermidine | 1998 |
Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Drug Administration Schedule; Haloperidol; Limbic System; Male; Motor Activity; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Stress, Psychological; Time Factors | 1998 |
Failure to down regulate NMDA receptors in the striatum and nucleus accumbens associated with neuroleptic-induced dyskinesia.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Dizocilpine Maleate; Down-Regulation; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Male; Mastication; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Haloperidol potentiates the EEG slowing of MK-801 despite blocking its motor effects: implications for the PCP model of schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Hallucinogens; Haloperidol; Male; Motor Activity; Phencyclidine; Rats; Rats, Sprague-Dawley; Schizophrenia; Sleep, REM | 1998 |
An NR2B point mutation affecting haloperidol and CP101,606 sensitivity of single recombinant N-methyl-D-aspartate receptors.
Topics: Animals; Arginine; CHO Cells; Cricetinae; Dizocilpine Maleate; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Iodine Radioisotopes; Piperidines; Point Mutation; Receptors, N-Methyl-D-Aspartate | 1998 |
Postural effects of unilateral blockade of glutamatergic neurotransmission in the subthalamic nucleus on haloperidol-induced akinesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Anti-Dyskinesia Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Functional Laterality; Haloperidol; Male; Movement Disorders; Posture; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thalamic Nuclei | 1998 |
Preferential blockade by clozapine of hyperlocomotion induced by non-competitive NMDA antagonist MK-801.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzazepines; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Hyperkinesis; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Stereotyped Behavior; Sulpiride | 1998 |
Different effects of omega-conotoxin on penile erection, yawning and paraventricular nitric oxide in male rats.
Topics: Animals; Apomorphine; Calcium; Calcium Channel Blockers; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Nitrates; Nitric Oxide; omega-Conotoxin GVIA; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Peptides; Rats; Rats, Sprague-Dawley; Vasotocin; Yawning | 1998 |
Effects of 5-hydroxytryptamine2 receptor antagonism on the behavioral activation and immediate early gene expression induced by dizocilpine.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Haloperidol; HSP70 Heat-Shock Proteins; Immediate-Early Proteins; Immunohistochemistry; Ketanserin; Mice; Motor Activity; Proto-Oncogene Proteins c-fos; Ritanserin; Serotonin Antagonists | 1998 |
The role of striatal glutamate receptors in models of Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Haloperidol; Kynurenic Acid; Parkinson Disease; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate; Reserpine | 1998 |
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.
Topics: Animals; Apoptosis; Brain; Calcium Channel Blockers; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Haloperidol; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Muscarinic Antagonists; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1999 |
Glutamatergic and dopaminergic contributions to rat bladder hyperactivity after cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Benzazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Haloperidol; Rats; Rats, Sprague-Dawley; Sulpiride; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists | 1999 |
Binding of [3H]desglycinyl remacemide to rat brain membranes: association with the benzomorphan attachment site of the N-methyl-D-aspartic acid receptor channel.
Topics: Animals; Antipsychotic Agents; Benzomorphans; Binding Sites; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Male; Membrane Proteins; Neurons; Phenazocine; Phencyclidine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Tritium | 1999 |
Possible neural mechanisms involved in footshock stress-induced enhancement of exploratory behavior in mice.
Topics: Animals; Atropine; Central Nervous System; Diazepam; Dizocilpine Maleate; Electric Stimulation; Exploratory Behavior; Haloperidol; Male; Mianserin; Mice; Naltrexone; Phentolamine; Propranolol; Stress, Physiological | 1999 |
NMDA receptor blockade attenuates the haloperidol induction of Fos protein in the dorsal but not the ventral striatum.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Dizocilpine Maleate; Genes, fos; Haloperidol; Male; Neuroprotective Agents; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Chronic haloperidol and clozapine administration increases the number of cortical NMDA receptors in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antipsychotic Agents; Autoradiography; Cerebral Cortex; Clozapine; Corpus Striatum; Dizocilpine Maleate; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Spiperone; Tritium | 1999 |
Mice with reduced NMDA receptor expression display behaviors related to schizophrenia.
Topics: Animals; Antipsychotic Agents; Antisocial Personality Disorder; Behavior, Animal; Calcium Signaling; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Haloperidol; Male; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenic Psychology; Serotonin Antagonists; Sexual Behavior, Animal; Social Behavior; Stereotyped Behavior | 1999 |
State-dependent blockade of haloperidol-induced sensitization of catalepsy by MK-801.
Topics: Animals; Antipsychotic Agents; Catalepsy; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Role of adenosine and N-methyl-D-aspartate receptors in mediating haloperidol-induced gene expression and catalepsy.
Topics: Animals; Autoradiography; Catalepsy; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Genes, fos; Haloperidol; In Situ Hybridization; Male; Neuroprotective Agents; Neurotensin; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Purinergic P1 | 1999 |
The effects of subchronic haloperidol on intact and dizocilpine-disrupted sensorimotor gating.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1999 |
Differential effects of haloperidol and clozapine on ionotropic glutamate receptors in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Aspartic Acid; Binding Sites; Brain; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1999 |
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 1999 |
Intracellular modulation of NMDA receptor function by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Blotting, Northern; Cells, Cultured; Clozapine; Cycloserine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Neostriatum; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2000 |
Effects of antipsychotic drugs on neurotoxicity, expression of fos-like protein and c-fos mRNA in the retrosplenial cortex after administration of dizocilpine.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Haloperidol; Immunohistochemistry; In Situ Hybridization; Limbic System; Nervous System; Olanzapine; Pirenzepine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Risperidone; RNA, Messenger | 2000 |
Amygdaloid N-methyl-D-aspartate and gamma-aminobutyric acid(A) receptors regulate sensorimotor gating in a dopamine-dependent way in rats.
Topics: Amygdala; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Haloperidol; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia | 2000 |
[Glutamate receptor antagonists attenuate experimental catalepsy in rats].
Topics: Adamantane; Animals; Antipsychotic Agents; Ataxia; Catalepsy; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Stereotyped Behavior | 2000 |
Effects of MK801 and neuroleptics on prepulse inhibition: re-examination in two strains of rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Hippocampus; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Species Specificity | 2000 |
Glutamatergic regulation of haloperidol-induced c-fos expression in the rat striatum and nucleus accumbens.
Topics: Animals; Cell Nucleus; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Routes; Excitatory Amino Acid Antagonists; Haloperidol; Male; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2001 |
Uncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors alter the mRNA expression of proteins associated with the NMDA receptor complex.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Haloperidol; Image Processing, Computer-Assisted; In Situ Hybridization; Isoenzymes; Male; Membrane Proteins; Nerve Tissue Proteins; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; SAP90-PSD95 Associated Proteins | 2001 |
Stimulatory role of dopamine on fibroblast growth factor-2 expression in rat striatum.
Topics: Animals; Apomorphine; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fibroblast Growth Factor 2; Haloperidol; Male; Nicotine; Nicotinic Agonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stereoisomerism | 2001 |
Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Topics: Animals; Brain; Cell Line; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Kinetics; Mice; Mutation; Phenols; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Spermidine | 2001 |
Startle and sensorimotor gating in rats lacking CCK-A receptors.
Topics: Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Brain; Cholecystokinin; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Neural Inhibition; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Reflex, Startle | 2001 |
A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Piperidines; Risperidone; Serotonin Antagonists | 2001 |
Neuroprotective and neurotoxic properties of the 'inert' gas, xenon.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Biomarkers; Brain; Brain Injuries; Dizocilpine Maleate; Female; Gene Expression; Haloperidol; Ketamine; Models, Animal; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Xenon | 2002 |
Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glucose; Glutamates; Haloperidol; Neurons; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sodium Azide | 2002 |
Systemic administration of MK-801 produces an abnormally persistent latent inhibition which is reversed by clozapine but not haloperidol.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Conditioning, Psychological; Disease Models, Animal; Dizocilpine Maleate; Drinking Behavior; Haloperidol; Inhibition, Psychological; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology | 2003 |
Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Male; Neuronal Plasticity; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Transmission | 2003 |
The ability of new non-competitive glutamate receptor blockers to weaken motor disorders in animals.
Topics: Animals; Ataxia; Behavior, Animal; Catalepsy; Diamines; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Kainic Acid; Memantine; Mice; Mice, Inbred Strains; N-Methylaspartate; Quaternary Ammonium Compounds; Seizures; Structure-Activity Relationship; Time Factors | 2003 |
Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice.
Topics: Amino Acids; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluorobenzenes; Haloperidol; Hyperkinesis; Mice; Motor Activity; Piperidines; Receptors, Metabotropic Glutamate; Serotonin Antagonists; Time Factors; Xanthenes | 2003 |
Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens.
Topics: Animals; Cell Count; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Haloperidol; Immunohistochemistry; Nucleus Accumbens; Phenols; Piperidines; Proto-Oncogene Proteins c-fos; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
Neuroleptic-like effects of gamma-hydroxybutyrate: interactions with haloperidol and dizocilpine.
Topics: Animals; Antipsychotic Agents; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2004 |
Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Bromodeoxyuridine; Cell Count; Cell Division; Cell Survival; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Haloperidol; Hippocampus; Immunohistochemistry; Male; Phenotype; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley | 2004 |
Glutamatergic regulation of long-term grafts of fetal lateral ganglionic eminence in a rat model of Huntington's disease.
Topics: Animals; Brain Injuries; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Fetal Tissue Transplantation; Fluorescent Antibody Technique; Glutamine; Haloperidol; Huntington Disease; Immunohistochemistry; Male; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2004 |
Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Catalepsy; Cell Count; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Ethylenediamines; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Haloperidol; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Piperidines; Prazosin; Prosencephalon; Proto-Oncogene Proteins c-fos; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors | 2004 |
Habituation of acoustic startle is disrupted by psychotomimetic drugs: differential dependence on dopaminergic and nitric oxide modulatory mechanisms.
Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dextroamphetamine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Habituation, Psychophysiologic; Hallucinogens; Haloperidol; Male; Mice; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phencyclidine; Reflex, Startle | 2004 |
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.
Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Grooming; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Piperidines; Schizophrenia | 2004 |
Atypical antipsychotic profile of flunarizine in animal models.
Topics: Administration, Oral; Animals; Catalepsy; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flunarizine; Haloperidol; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Time Factors | 2005 |
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling.
Topics: Acetylation; Animals; Animals, Newborn; Blotting, Southern; Blotting, Western; Chromatin Assembly and Disassembly; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Genes, fos; Glial Fibrillary Acidic Protein; Glutamic Acid; Haloperidol; Histones; Immunohistochemistry; In Vitro Techniques; Indoles; Isoquinolines; Male; Methylation; Mice; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thionucleotides; Time Factors | 2004 |
Activation of D1, but not D2 receptors potentiates dizocilpine-mediated disruption of prepulse inhibition of the startle.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reflex, Startle | 2005 |
The effect of tryptophan depletion on the action of haloperidol in MK-801-treated rats.
Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Haloperidol; Male; Motor Activity; Rats; Rats, Wistar; Serotonin; Tryptophan | 2004 |
A simple rodent assay for the in vivo identification of agents with potential to reduce levodopa-induced dyskinesia in Parkinson's disease.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amantadine; Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Idazoxan; Levodopa; Male; Motor Activity; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reserpine | 2005 |
Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists.
Topics: Animals; Benzazepines; Cell Count; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Gene Expression; Genes, fos; Haloperidol; In Situ Hybridization; Mice; Mice, Knockout; Motor Activity; Phencyclidine; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
The dopaminergic stabilizers (-)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Schizophrenic Psychology; Social Behavior | 2005 |
Kappa opioid receptor activation disrupts prepulse inhibition of the acoustic startle in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acoustic Stimulation; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Inhibition, Psychological; Male; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, kappa; Reflex, Startle | 2005 |
Streptozotocin-induced diabetes differentially modifies haloperidol- and gamma-hydroxybutyric acid (GHB)-induced catalepsy.
Topics: Animals; Catalepsy; Diabetes Mellitus, Experimental; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Hydroxybutyrates; Male; Rats; Rats, Sprague-Dawley; Regression Analysis | 2005 |
Cinnarizine has an atypical antipsychotic profile in animal models of psychosis.
Topics: Amphetamine; Animals; Antipsychotic Agents; Calcium Channel Blockers; Catalepsy; Central Nervous System Stimulants; Cinnarizine; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Psychotic Disorders | 2005 |
Modulation of striatal dopamine release in vitro by agonists of the glycineB site of NMDA receptors; interaction with antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Haloperidol; Magnesium; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Salicylamides | 2005 |
Clozapine but not haloperidol suppresses the changes in the levels of neuropeptides in MK-801-treated rat brain regions.
Topics: Animals; Brain; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Haloperidol; Male; Neuropeptides; Rats; Rats, Wistar; Sex Factors | 2006 |
Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Haloperidol; Motor Activity; Neural Inhibition; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Vitamin D Deficiency | 2006 |
Fine-tuning of awake prefrontal cortex neurons by clozapine: comparison with haloperidol and N-desmethylclozapine.
Topics: Action Potentials; Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Male; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Wakefulness | 2007 |
Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity.
Topics: Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Dizocilpine Maleate; Glutamic Acid; Haloperidol; L-Lactate Dehydrogenase; Neuroglia; Neurons; Nitric Oxide Synthase Type I; ras-GRF1; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2007 |
Suppressive effect of clozapine but not haloperidol on the increases of neuropeptide-degrading enzymes and glial cells in MK-801-treated rat brain regions.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Haloperidol; Metalloendopeptidases; Neuroglia; Oligonucleotides; Prolyl Oligopeptidases; Rats; Rats, Wistar; Serine Endopeptidases | 2007 |
Proteome analysis after co-administration of clozapine or haloperidol to MK-801-treated rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; Haloperidol; Male; Proteome; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin Antagonists; Thalamus | 2007 |
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Schizophrenia; Serotonin; Synaptic Transmission | 2007 |
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Haloperidol; Head Movements; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperidines; Prolactin; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Urea | 2007 |
Effects of antipsychotic treatments and D-serine supplementation on the electrophysiological activation of midbrain dopamine neurons induced by the noncompetitive NMDA antagonist MK 801.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dizocilpine Maleate; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Haloperidol; Male; Mesencephalon; Microelectrodes; Neurons; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 2007 |
Alterations of hippocampal and prefrontal GABAergic interneurons in an animal model of psychosis induced by NMDA receptor antagonism.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; gamma-Aminobutyric Acid; Haloperidol; Hippocampus; Interneurons; Male; Neural Inhibition; Neurons; Prefrontal Cortex; Psychotic Disorders; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2007 |
D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Cognition; Cognition Disorders; Dizocilpine Maleate; Exploratory Behavior; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nootropic Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Serine; Statistics, Nonparametric | 2008 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Risperidone and ritanserin but not haloperidol block effect of dizocilpine on the active allothetic place avoidance task.
Topics: Animals; Avoidance Learning; Behavior, Animal; Dizocilpine Maleate; Haloperidol; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Time Factors | 2008 |
Epinephrine potentiates antipsychotic, but not cataleptogenic effect of haloperidol in rats.
Topics: Animals; Antipsychotic Agents; Catalepsy; Dizocilpine Maleate; Drug Synergism; Epinephrine; Haloperidol; Injections, Intramuscular; Male; Rats | 2007 |
Mechanisms for metoclopramide-mediated sensitization and haloperidol-induced catalepsy in rats.
Topics: Animals; Behavior, Animal; Binding, Competitive; Catalepsy; Cerebral Cortex; Dizocilpine Maleate; Dopamine Antagonists; Haloperidol; Male; Metoclopramide; Neostriatum; Rats; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Spiperone | 2008 |
Short-term selective breeding for high and low prepulse inhibition of the acoustic startle response; pharmacological characterization and QTL mapping in the selected lines.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Catalepsy; Central Nervous System Stimulants; Chromosome Mapping; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Genotype; Haloperidol; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Phenotype; Reflex, Startle; Species Specificity | 2008 |
The putative antipsychotic alstonine reverses social interaction withdrawal in mice.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Interpersonal Relations; Male; Mice; Motor Activity; Secologanin Tryptamine Alkaloids; Social Behavior Disorders; Sulpiride | 2008 |
Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist.
Topics: Amino Acids; Analysis of Variance; Animals; Anti-Dyskinesia Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Exploratory Behavior; Haloperidol; Hyperkinesis; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Metabotropic Glutamate | 2008 |
Prenatal protein deprivation alters dopamine-mediated behaviors and dopaminergic and glutamatergic receptor binding.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Haloperidol; Locomotion; Male; Pregnancy; Prenatal Nutritional Physiological Phenomena; Protein Binding; Protein Deficiency; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Glutamate; Sex Factors | 2008 |
Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Benzamides; Central Nervous System Stimulants; Cognition; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nitroarginine; Piperidines; Rats; Rats, Wistar; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 2009 |
Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells.
Topics: Animals; Cell Line, Tumor; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Gene Expression; Glioma; Haloperidol; HSP70 Heat-Shock Proteins; Linear Models; Rats; Risperidone; Time Factors | 2008 |
WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics.
Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Azepines; Catalepsy; Clozapine; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Haloperidol; Indoles; Male; Mice; Rats; Rats, Sprague-Dawley; Reflex, Startle; Serotonin 5-HT2 Receptor Agonists; Stereotyped Behavior | 2009 |
Developmentally regulated and thalamus-selective induction of leiomodin2 gene by a schizophrenomimetic, phencyclidine, in the rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cytoskeletal Proteins; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hallucinogens; Haloperidol; Male; Microfilament Proteins; Muscle Proteins; Myocardium; Oligonucleotide Array Sequence Analysis; Phencyclidine; Rats; Rats, Wistar; RNA, Messenger; Thalamus; Time Factors; Tropomodulin | 2009 |
Effects of antipsychotic drugs on MK-801-induced attentional and motivational deficits in rats.
Topics: Animals; Antipsychotic Agents; Attention; Clozapine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motivation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Reward | 2009 |
D-Serine and a glycine transporter-1 inhibitor enhance social memory in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Social Behavior; Time Factors | 2010 |
Modulation of prepulse inhibition and stereotypies in rodents: no evidence for antipsychotic-like properties of histamine H3-receptor inverse agonists.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzofurans; Dizocilpine Maleate; Drug Inverse Agonism; Haloperidol; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Male; Methamphetamine; Mice; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stereotyped Behavior | 2010 |
N-methyl d-aspartate receptors are involved in the induction, but not expression stage of amphetamine sensitization in schedule-induced polydipsia in rats.
Topics: Animals; Dextroamphetamine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thirst | 2010 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Effect of tandospirone, a serotonin-1A receptor partial agonist, on information processing and locomotion in dizocilpine-treated rats.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Isoindoles; Male; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Schizophrenia; Sensory Gating; Serotonin Receptor Agonists | 2010 |
Effects of aripiprazole and haloperidol on progression to schizophrenia-like behavioural abnormalities and apoptosis in rodents.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antipsychotic Agents; Apoptosis; Aripiprazole; Behavioral Symptoms; Disease Models, Animal; Dizocilpine Maleate; Haloperidol; In Situ Nick-End Labeling; Inhibition, Psychological; Male; Methamphetamine; Microdialysis; Motor Activity; Neuroprotective Agents; Piperazines; Quinolones; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia | 2011 |
The role of NMDA and AMPA/Kainate receptors in the consolidation of catalepsy sensitization.
Topics: Analysis of Variance; Animals; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2011 |
MK-801 alters Na+, K+-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fluoresceins; Haloperidol; Lipid Peroxidation; Male; Membranes; Nerve Tissue Proteins; Olanzapine; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Sulpiride; Thiobarbituric Acid Reactive Substances; Zebrafish | 2012 |
Effects of sertraline on experimental mouse models of psychosis.
Topics: Animals; Antidepressive Agents; Apomorphine; Catalepsy; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Haloperidol; Mice; Motor Activity; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Time Factors | 2012 |
Reversal of oxidative stress by histamine H₃ receptor-ligands in experimental models of schizophrenia.
Topics: Amphetamine; Animals; Antioxidants; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain Chemistry; Catalase; Catalepsy; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutathione; Haloperidol; Histamine H3 Antagonists; Male; Mice; Motor Activity; Oxidative Stress; Rats; Schizophrenia; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Dysequilibrium of neuronal proliferation and apoptosis in a pharmacological animal model of psychosis.
Topics: Animals; Antigens, Nuclear; Apoptosis; Cell Nucleus; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Gene Expression Profiling; Gene Expression Regulation; Haloperidol; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Oligonucleotide Array Sequence Analysis; Proliferating Cell Nuclear Antigen; Psychoses, Substance-Induced; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2012 |
Differential effects of antipsychotics on hippocampal presynaptic protein expressions and recognition memory in a schizophrenia model in mice.
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Frontal Lobe; Haloperidol; Hippocampus; Male; Mice; Motor Activity; Presynaptic Terminals; Recognition, Psychology; Schizophrenia; Synaptophysin; Synaptosomal-Associated Protein 25 | 2012 |
Glutamatergic dysbalance and oxidative stress in in vivo and in vitro models of psychosis based on chronic NMDA receptor antagonism.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Hippocampus; Male; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tyrosine | 2013 |
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes | 2014 |
Effects of the nicotinic α7 receptor partial agonist GTS-21 on NMDA-glutamatergic receptor related deficits in sensorimotor gating and recognition memory in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Apomorphine; Benzylidene Compounds; Clozapine; Cognition; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; Haloperidol; Male; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Recognition, Psychology; Reflex, Startle; Sensory Gating | 2014 |
Glutamatergic neurotransmission in the inferior colliculus influences intrastriatal haloperidol-induced catalepsy.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; N-Methylaspartate; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2014 |
Selective blockade of N-methyl-D-aspartate channels in combination with dopamine receptor antagonism induces loss of the righting reflex in mice, but not immobility.
Topics: Animals; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Haloperidol; Immobilization; Male; Mice; Receptors, N-Methyl-D-Aspartate; Reflex, Righting | 2015 |
Glutamate receptor 1 phosphorylation at serine 845 contributes to the therapeutic effect of olanzapine on schizophrenia-like cognitive impairments.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Hippocampus; Male; Memory, Short-Term; Neuronal Plasticity; Olanzapine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Schizophrenia; Spatial Learning | 2014 |
Involvement of glutamatergic and GABAergic transmission in MK-801-increased gamma band oscillation power in rat cortical electroencephalograms.
Topics: Amino Acids; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Excitatory Amino Acid Antagonists; Fluorobenzenes; GABA Agents; Gamma Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Riluzole; Triazoles | 2014 |
Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Glycine; Glycine Plasma Membrane Transport Proteins; Haloperidol; Imipramine; Locomotion; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Serine; Swimming | 2015 |
Dopamine D2/D3 but not dopamine D1 receptors are involved in the rapid antidepressant-like effects of ketamine in the forced swim test.
Topics: Animals; Antidepressive Agents; Benzazepines; Benzothiazoles; Dizocilpine Maleate; Fluoxetine; Haloperidol; Ketamine; Male; Mice; Motor Activity; Pramipexole; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, N-Methyl-D-Aspartate; Swimming | 2015 |
Temporal and spatial transcriptional fingerprints by antipsychotic or propsychotic drugs in mouse brain.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Dizocilpine Maleate; Gene Expression Profiling; Gene Expression Regulation; Hallucinogens; Haloperidol; Methamphetamine; Mice; Olanzapine; Phencyclidine; Receptors, Dopamine D2 | 2015 |
Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats.
Topics: Acoustic Stimulation; Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Habenula; Haloperidol; Mecamylamine; Nicotine; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reflex, Startle; Sensory Gating | 2015 |
AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.
Topics: Adult; Animals; Antipsychotic Agents; Behavior, Animal; Blotting, Western; Brain; Cell Membrane; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; Haloperidol; Heat-Shock Proteins; Hippocampus; Humans; Immunohistochemistry; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Knockout; Middle Aged; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phenotype; Schizophrenia; Serotonin; Shab Potassium Channels; Young Adult | 2016 |
Effects of NMDA receptor antagonists and antipsychotics on high frequency oscillations recorded in the nucleus accumbens of freely moving mice.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Ketamine; Male; Mice; Nucleus Accumbens; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2015 |
Roles of NMDA and dopamine in food-foraging decision-making strategies of rats in the social setting.
Topics: Animals; Benzazepines; Competitive Behavior; Decision Making; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Food Preferences; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2016 |
Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine.
Topics: Amino Acids; Animals; Antipsychotic Agents; Benzodiazepines; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Haloperidol; Ketamine; Male; Olanzapine; Prepulse Inhibition; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia | 2016 |
Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Contamination; Drug Synergism; Glycine; Haloperidol; Male; Memory; Memory Disorders; Neuroprotective Agents; PQQ Cofactor; Rats; Rats, Sprague-Dawley; Serine; Social Behavior; Time Factors | 2016 |
The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia.
Topics: Aged; Animals; Antipsychotic Agents; Astrocytes; Cells, Cultured; Chronic Disease; Cohort Studies; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glycogen Phosphorylase; Haloperidol; Humans; Isoenzymes; Male; Mice, Inbred C57BL; Prefrontal Cortex; rac1 GTP-Binding Protein; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2016 |
Antidepressant effect of pramipexole in mice forced swimming test: A cross talk between dopamine receptor and NMDA/nitric oxide/cGMP pathway.
Topics: Animals; Antidepressive Agents; Arginine; Benzothiazoles; Cyclic GMP; Dizocilpine Maleate; Haloperidol; Immobilization; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pramipexole; Receptors, Dopamine; Signal Transduction; Sildenafil Citrate; Swimming | 2016 |
Differential effects of antipsychotic and propsychotic drugs on prepulse inhibition and locomotor activity in Roman high- (RHA) and low-avoidance (RLA) rats.
Topics: Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Locomotion; Male; Prepulse Inhibition; Rats; Receptor, Serotonin, 5-HT2A; Reflex, Startle; Schizophrenia; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists | 2017 |
Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway.
Topics: Animals; Binding Sites; Corpus Striatum; Cycloserine; Dizocilpine Maleate; Dopamine; Glycine; Haloperidol; Hypokinesia; Male; Mice; Microdialysis; Microinjections; Motor Disorders; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 2017 |
Investigation of the synergistic effects of haloperidol combined with Calculus Bovis Sativus in treating MK-801-induced schizophrenia in rats.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Biological Availability; Biological Products; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Haloperidol; Male; Phytotherapy; Rats, Sprague-Dawley; Schizophrenia | 2018 |
Effects of haloperidol inhalation on MK-801- and memantine-induced locomotion in mice.
Topics: Administration, Inhalation; Animals; Antipsychotic Agents; Behavior, Animal; Betahistine; Dizocilpine Maleate; Haloperidol; Injections, Intraperitoneal; Male; Memantine; Mice; Mice, Inbred C57BL; Motor Activity | 2020 |
Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling 'positive-like' symptoms of schizophrenia.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Schizophrenia | 2021 |
Chronic oral olanzapine treatment but not haloperidol decreases [
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Diet; Dizocilpine Maleate; Haloperidol; Male; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 2022 |
Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Hypoxia; Ligands; Nomifensine; Ouabain; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2022 |