haloperidol has been researched along with dextromethorphan in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 15 (46.88) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| DeHaven-Hudkins, DL; Hudkins, RL; Mailman, RB | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lever, JR; Lever, SZ; Nahas, RI | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
| Peng, Y; Welsh, WJ; Zhang, Q | 1 |
| Hudzik, TJ | 1 |
| Calder, LD; Karler, R | 1 |
| Musacchio, JM; Zhou, GZ | 1 |
| Enna, SJ; Karbon, EW | 1 |
| Karbon, EW; Naper, K; Pontecorvo, MJ | 1 |
| Balestra, B; Candura, SM; Coccini, T; Costa, LG; Iapadre, N; Manzo, L; Tonini, M | 1 |
| Klein, M; Musacchio, J; Paturzo, JJ; Zhou, GZ | 1 |
| Klein, M; Musacchio, JM; Paturzo, JJ | 1 |
| Appleyard, SM; Chavkin, C; Connor, M; Patterson, TA | 1 |
| DeCoster, MA; Klette, KL; Knight, ES; Tortella, FC | 1 |
| Cooper, TB; Klein, M; Musacchio, JM | 1 |
| Shi, GG; Xu, SF | 1 |
| Hashimoto, K; Iyo, M; Minabe, Y; Narita, N; Yamazaki, K | 1 |
| Chang, WH; Deng, HC; Hu, OY; Jann, MW; Lane, HY; Lin, HN | 1 |
| Christie, MJ; Ingram, SL; Kassiou, M; Nguyen, VH | 1 |
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM | 1 |
| Chen, YC; Holmes, A | 1 |
| Kumar, V; Pandey, P; Prakash, A; Prasad, K | 1 |
| Doello, K; Mesas, C; Ortiz, R; Perazzoli, G; Quiñonero, F; Rama, AR; Vélez, C | 1 |
2 review(s) available for haloperidol and dextromethorphan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacological characterization of sigma binding sites in guinea pig brain membranes.
Topics: Animals; Brain; Dextromethorphan; Drug Synergism; Guinea Pigs; Haloperidol; Membranes; Phenytoin; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1991 |
30 other study(ies) available for haloperidol and dextromethorphan
| Article | Year |
|---|---|
Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds.
Topics: Animals; Binding Sites; Brain; Cyclopentanes; Guinea Pigs; Molecular Weight; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1994 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Synthesis and structure-activity relationships of N-(3-phenylpropyl)-N'-benzylpiperazines: Potent ligands for sigma1 and sigma2 receptors.
Topics: Combinatorial Chemistry Techniques; Ligands; Molecular Structure; Piperazines; Quantitative Structure-Activity Relationship; Receptors, sigma | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management.
Topics: Animals; Binding Sites; Blood-Brain Barrier; Drug Design; Guinea Pigs; Half-Life; Humans; Microsomes, Liver; Molecular Dynamics Simulation; Neuralgia; Pain Management; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship; Rats; Receptors, sigma; Sigma-1 Receptor; Triazoles | 2021 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Computer Simulation; Dextromethorphan; Guanidines; Guinea Pigs; Haloperidol; Kinetics; Male; Models, Biological; Piperidines; Receptors, Opioid; Receptors, sigma; Tritium | 1991 |
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Membranes; Phenazocine; Phenytoin; Piperidines; Receptors, Opioid; Receptors, sigma | 1991 |
Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Carbazoles; Dextromethorphan; Electric Stimulation; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Motor Neurons; Myenteric Plexus; Parasympathetic Nervous System; Phenazocine; Pyrimidines; Receptors, Opioid; Receptors, sigma | 1991 |
The effect of sigma ligands on dextromethorphan binding sites in the guinea pig.
Topics: Animals; Binding Sites; Dextromethorphan; Guinea Pigs; Hallucinogens; Haloperidol; In Vitro Techniques; Kinetics; Levorphanol; Piperidines; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
The effect of prototypic sigma ligands on the binding of [3H]dextromethorphan to guinea pig brain.
Topics: Animals; Antitussive Agents; Binding, Competitive; Brain; Dextromethorphan; Guinea Pigs; Haloperidol; Levorphanol; Pentazocine; Receptors, Opioid; Receptors, Opioid, delta | 1989 |
Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site.
Topics: Animals; Binding Sites; Binding, Competitive; Carbazoles; Dextromethorphan; Female; Guanidines; Haloperidol; Liver; Mazindol; Oocytes; Pentazocine; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, sigma; Xenopus laevis; Zinc | 1994 |
Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures.
Topics: Animals; Calcium; Cells, Cultured; Cyclazocine; Cyclopentanes; Dextromethorphan; Glutamic Acid; Guanidines; Haloperidol; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Pentazocine; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Effects of haloperidol and reduced haloperidol on binding to sigma sites.
Topics: Animals; Binding Sites; Brain; Dextromethorphan; Guinea Pigs; Haloperidol; Male; Oxidation-Reduction; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1994 |
Effect of phencyclidine on contraction of porcine coronary vessel strips.
Topics: Animals; Biological Assay; Coronary Vessels; Dextromethorphan; Dizocilpine Maleate; Haloperidol; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Phenazocine; Phencyclidine; Receptors, Phencyclidine; Receptors, sigma; Swine | 1993 |
Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
Topics: Animals; Anisoles; Antitussive Agents; Cerebral Cortex; Dextromethorphan; Haloperidol; Hydroxyindoleacetic Acid; Ligands; Male; p-Chloroamphetamine; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Serotonin Agents | 1995 |
Dextromethorphan phenotyping and haloperidol disposition in schizophrenic patients.
Topics: Adult; Asian People; Basal Ganglia Diseases; Dextromethorphan; Female; Haloperidol; Humans; Male; Phenotype; Schizophrenia; White People | 1997 |
Sigma-binding site ligands inhibit K+ currents in rat locus coeruleus neurons in vitro.
Topics: Action Potentials; Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Cell Membrane; Dextromethorphan; Dopamine Antagonists; Enkephalin, Methionine; Excitatory Amino Acid Antagonists; Guanidines; Haloperidol; In Vitro Techniques; Ligands; Locus Coeruleus; Male; Narcotics; Neurons; Pentazocine; Potassium Channels; Rats; Rats, Sprague-Dawley | 1998 |
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
Effects of dextromethorphan on dopamine dependent behaviours in rats.
Topics: Animals; Antitussive Agents; Apomorphine; Behavior, Animal; Catalepsy; Dextroamphetamine; Dextromethorphan; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2007 |
Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: modulation by genetic strain and stress.
Topics: Alcoholic Intoxication; Animals; Ataxia; Carbamazepine; Central Nervous System Depressants; Conscious Sedation; Dextromethorphan; Ethanol; Excitatory Amino Acid Agents; Fructose; Haloperidol; Hypothermia; Lamotrigine; Male; Memantine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Oxcarbazepine; Species Specificity; Stress, Psychological; Topiramate; Triazines | 2009 |
Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis.
Topics: Binding Sites; Computer Simulation; Coronavirus Nucleocapsid Proteins; COVID-19; COVID-19 Drug Treatment; Dextromethorphan; Haloperidol; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Pandemics; Protein Binding; Protein Interaction Domains and Motifs; SARS-CoV-2 | 2020 |
Antitumor Effect of Traditional Drugs for Neurological Disorders: Preliminary Studies in Neural Tumor Cell Lines.
Topics: Adult; Apoptosis; Biperiden; Brain Neoplasms; Cell Line, Tumor; Dextromethorphan; Fingolimod Hydrochloride; Glioblastoma; Haloperidol; Humans; Levetiracetam; Methotrimeprazine; Valproic Acid | 2022 |